ライフサイエンスコーパス: since

1 ceous (100 to 110 Ma) and remained high ever since.

2 lchicine belongs to the oldest drugs (in use since 1500 BC), its pharmacological potential as a lead

3 (N) to the environment has increased 10-fold since 1860 and is expected to increase by a further ~75%

4 The rate of global-mean sea-level rise since 1900 has varied over time, but the contributing fa

5 d a mean vertebrate decline of more than 50% since 1970 (Living Planet Index(2)).

6 Obesity has tripled worldwide since 1975 as environments are becoming more obesogenic.

7 iruses (IAVs) have caused seasonal epidemics since 1977.

8 ds has reduced ('short-staying') by ~38 days since 1989.

9 synthesis (S phase) inhibitor, has been used since 1991 for outpatient treatment of women with stable

10 hospitalizations and prescription medication since 1994.

11 This article reviews progress since 1997 relevant to TBM and other candidate morphogen

12 Despite this, since 1997, dollars invested in PDAC research produced a

13 stration's share of U.S. health expenditures since 1999, 2.4 percentage points was due to growth in p

14 A systematic review of published literature since 2000 on the use of omentoplasty during APR for can

15 Since 2002, a global epidemic of acute hepatitis C virus

16 rons stable and O. taurus increasing by 800% since 2003.

17 nal study of pediatric BAV patients followed since 2004 was performed.

18 white race), and more recent entry to care (since 2005 compared with 1994-2004).

19 s have circulated continuously in Bangladesh since 2007, and active surveillance has detected viral e

20 early diagnosis of PDAC has decreased by 19% since 2007.

21 -47.1 per mille to -47.3 per mille observed since 2008, has been attributed to increased emissions f

22 ia of primary qualitative research published since 2010 and focussing on the UK as the host country.

23 n of protected areas by national governments since 2010 has had limited success in increasing the cov

24 related IDU or substance use disorder terms since 2011.

25 .30 million), representing an 11.4% increase since 2012 (16.0% increase in LC deaths; 8.7% increase i

26 d optometry practices have increased rapidly since 2012, with some platform companies having already

27 care, with an emphasis on articles published since 2014.

28 breaks of urethritis in multiple U.S. cities since 2015, other mucosal infections, and cases of invas

29 Since 2017, CARD has expanded through extensive curation

30 Since 2017, there has been a global slowdown in the redu

31 ificant progress made on this series of MOFs since 2018 is summarized and an update on the current st

32 This review highlights the work accomplished since 2018 which focuses on using Raman spectroscopy and

33 COVID-19 has spread worldwide since 2019 and is now a severe threat to public health.

34 the University of California, San Francisco since 2019.

35 documenting deep-ocean delta(13)C evolution since 35 million years ago (Ma).

36 of thermal damage in the UHPH-treated musts, since 5-hydroxymethylfurfural was not detected.

37 drought was the second driest 19-year period since 800 CE, exceeded only by a late-1500s megadrought.

38 lants have a narrow range of grana diameters since a larger diffusion distance for plastocyanin would

39 /L level was safety for oral administration, since a minor number of dead cells were found in red col

40 ta fusion and PARADISe presented advantages, since a more comprehensive understanding of the relation

41 reat importance for archaeological sciences, since a predominantly European haplogroup has been ident

42 Since a wide variety of metal-specific DNAzymes can be o

43 rterly study visits, symptoms that developed since acute EVD were recorded and blood was collected fo

44 Yet since AF is often asymptomatic, many individuals with AF

45 Since Akt can activate beta-catenin, inhibiting this int

46 tions in the missing hand regardless of time since amputation or level of amputation.

47 showed E148Q heterozygous mutation in exon 2.Since an adult case of PFAPA syndrome is likely to be ma

48 Since ancient times it is known that melancholia and sle

49 has been valued as a powerful antimicrobial since ancient times.

50 ids (QSLs) have continually been of interest since Anderson's 1973 ground-breaking idea.

51 alternative antigen for vaccine development, since antibodies to NS1 do not bind to the virion, there

52 rmal primary care diagnoses was a limitation since ascertaining depression and ADHD from prescription

53 rd to make landfall on the Florida panhandle since at least 1851 CE (Common Era), and it resulted in

54 a model with nearly constant crustal silica since at least the early Archean.

55 Since ATI showed a broad range of optimal thresholds, ex

56 Since bacterial translation is often modulated by enhanc

57 2 (SARS-CoV-2), emerged in late 2019 and has since become a global pandemic.

58 However, the original site has since been completely quarried away, and-although the cr

59 l infection control campaign, but rates have since been static.

60 mental delay and medical refractory seizures since birth most recently presented with continuous simp

61 unique approach to managing such infections since both direct microbial pathogens killing and matrix

62 Since C3G has no or very low toxicity, it could be poten

63 Since catalase is a key enzyme for the dismutation of vi

64 er toxicological investigation, particularly since catechol metabolites are likely reactive and toxic

65 Since chemotherapy represents the established backbone o

66 s status may represent persistent infection, since Chlamydia genomes proliferated in the same tissues

67 Since cures are currently unavailable, major efforts in

68 Since cybrid cell lines with 73% m.3243A > G heteroplasm

69 Since dark web marketplaces are unregulated, they do not

70 air bundle establishment or positions of HCs since daughter HCs are known to switch positions with ea

71 ntial for the direct analysis of DBS samples since DBS elution and HF-LPME are performed simultaneous

72 The association varied according to time since diagnosis with an adjusted IRR for 1 to 3 months o

73 nguish patients that lived for over 10 years since diagnosis, from those who did not survive at least

74 limited, suggesting extensive rearrangements since divergence.

75 Since DS slides are not standard clinical practice, we a

76 Since dynamic programing enables the detection one step

77 induced FGR, with relevance to human disease since dysregulation of placental Htra1 and placental oxi

78 s (Cav(L)) and anoctamin 1 (ANO1) was tested since each is essential for SW and tone generation.

79 re than 1800 urine samples in our laboratory since early 2019.

80 Since ELS effects are often sexually dimorphic and amygd

81 angstrom precision is, however, challenging, since epitaxially grown 2D layers exhibit complex restru

82 iratory network is far from being understood since experimental tools that measure neural activity ac

83 r designable structures remains a challenge, since few existing metrics capture high-level structural

84 ection for inherent suppressors, is critical since field release studies are in progress.

85 Since firing in bursts has been associated to neuropepti

86 unger age at Fontan surgery, and longer time since Fontan procedure (P<0.05).

87 Also, since formaldehyde is the byproduct of biochemical react

88 This principle applies more broadly since genomic analysis indicates suboptimal canonical mi

89 Since graphene, a variety of 2D materials have been fabr

90 Since herpesviruses are experts at coopting cellular fun

91 opathies, it is a diagnosis not to be missed since high-dose riboflavin per oral supplementation is o

92 Since HIV-1 fusion inhibitor peptides need to be embedde

93 Since HMGA1 proteins also carry multiple "AT-hook" DNA-b

94 In addition, since human skin proteins were also identified, this met

95 Since Igf1r deletion allows the evasion of early develop

96 Since IL-10 suppresses T cell function, this suggests th

97 ect costs per case of enteric fever incurred since illness onset by phone after enrollment and 6 week

98 Since immune cells display oscillations in numbers and f

99 synaptic contacts support such coordination since incoming action potentials would depolarize the de

100 -CoV-2) in an older population is important, since increased incidences of illness and death from cor

101 ience as a measure of costs of reproduction, since initial detections are often associated with first

102 Since ion transfer is diffusion-limited, by changing the

103 Imaging is an extremely intriguing tool since it assumes a follow up to treatments to survey the

104 a central role in Alzheimer's disease (AD), since it drives the cognitive decline.

105 he fate of plastic waste is a pressing issue since it forms a visible and long-lived reminder of the

106 This is a critical issue since it has been shown that post-mortem time delay and

107 Since it is related to the generic perceptual inference

108 Since it is unknown whether influenza vaccine is leaky,

109 reatment was considered the best formulation since it presented the highest fatty acid retention (68.

110 r, SERS can be unreliable for biomedical use since it sacrifices reproducibility, uniformity, biocomp

111 differs essentially from other condensates, since it takes place simultaneously at +/- k(min).

112 Since its detection in swine, influenza D virus (IDV) ha

113 Since its discovery 150 years ago, the neural crest has

114 Since its emergence, the novel coronavirus has rapidly a

115 This process has remained enigmatic since its initial discovery >50 yr ago, but our understa

116 Since its release in 2019, we have produced a number of

117 aper, we analyse a global dataset of flights since July 2016.

118 rve to predict the post-HAA selectivity, and since KED is affected by the free energy of reaction and

119 Since l-argininosuccinic acid (ASA) is the characteristi

120 Since LAMA2-CMD patients are often diagnosed after advan

121 rtality were consistent irrespective of time since last PCI.

122 Since LINbase leverages the concept of Life Identificati

123 te the prevalence of 9 care states over time since linkage with respect to ART initiation, retention

124 Since lupus patients are prone to infections, groups of

125 Improving this practice is challenging since many clinicians did not train where CM is frequent

126 Since many phytoplankton species are elongated, these re

127 om temperature remain mysterious, especially since many tolerance-factor-based approaches predict CsP

128 Since March 2020, the national unemployment rate has inc

129 y for this disease presents inherent hurdles since MECP2 is expressed throughout the brain and its du

130 uded gender, calendar year, geography, years since medical school graduation, and subspecialty.

131 ds in medically relevant materials research, since microbial colonization of medical implants and dev

132 f microhomology-mediated end joining mostly, since microhomologies between human and BKPyV genomes we

133 as likely below one in each Australian state since mid-March and forecast that clinical demand would

134 Wnk1 is highly expressed in thymocytes, and since migration is important for thymocyte maturation, w

135 d, we find evidence of a segregation effect, since mobility contraction is stronger in municipalities

136 gic discontinuation in patients on treatment since more than 6 months and not infected with severe ac

137 Since most dramatic changes in genomic architectures are

138 Since multiple hemodynamic variables can simultaneously

139 anotechnology benefits modern vaccine design since nanomaterials are ideal for antigen delivery, as a

140 Since neural KynA levels dampen learning capacity, KynA

141 However, since neurogenesis declines dramatically with age, it is

142 A*01:01pos could benefit from such products, since no T cells recognizing any EBV-derived peptide in

143 Since NO(-) production is strongly associated with host

144 Since nonapoptotic membrane blebbing is now recognized a

145 vestigation of preschool asthma is important since not all children outgrow their illness during this

146 a major challenge to chemists and the focus since now has mostly been on the synthesis of NH(3).

147 Since nuclear envelope breakdown occurs during mitosis i

148 er, metabolic conditions are highly variable since nutrient uptake is not a uniform process.

149 ficantly associated with viral load was time since onset of symptoms.

150 Since optimality is accepted as a physical principle, th

151 is a method to be considered and recommended since outperforms other methods in proportional and non-

152 entify and ligate accessory pancreatic ducts since persistence of accessory ducts will lead to mainte

153 ependent on L. murinus-produced lactic acid, since pH neutralization of the conditioned medium aborte

154 Fe sources in Gram-positive human pathogens, since PiuA functions in the same way as SstD from Staphy

155 Since plant growth is intimately related to the effectiv

156 Since polyadenylation occurs co-transcriptionally, and s

157 The median time since polycythaemia vera diagnosis was 8.2 years (IQR 3.

158 of continuous online monitoring of propofol since polymerization of the surface produces sensor drif

159 Since potential strain differences could exist in A1 org

160 Since reactions in upper layers of the hierarchy impose

161 Since reactive oxygen species (ROS) is vitally involved

162 ved IL-13 was sufficient for RSV-driven AHR, since reconstitution of wild-type ILC2 rescued RSV-drive

163 ing the accuracy and reliability of results, since repeatability has been a problem in studies utiliz

164 Since RNA elements guide function in most RNA viruses, a

165 Since RNA secondary structures have only been defined fo

166 Since segregation-induced banded microstructures commonl

167 Since sestrin also protected muscles against aging-induc

168 addition, she reported progressive back pain since she was 5 years old.

169 B1 is shown to be a positive regulator of HR since silencing of VuPOB1 expression in transgenic B301

170 has advantages over conventional approaches, since simple modifications can be applied to recover a b

171 This result is particularly interesting since simplicity is crucial for the development of ECG-b

172 CD154 expression was TCR-mediated since single clones could be specifically restimulated.

173 Since SMI-32 antibody is considered to be a putative mar

174 Since spironolactone causes degradation of xeroderma pig

175 reservoir of influenza A viruses (IAVs) has since spurred decades of waterfowl surveillance efforts

176 -92) and related the thalamus volume to time since stroke, gender, intracortical volume, age, and les

177 Since surfaces are the interface between a material and

178 heteromers also applied to the steady-state, since sustained Btnl expression is required to maintain

179 The association of viral load with days since symptom onset was examined in a multivariable regr

180 pically requires a contiguous cell layer but since teeth penetrate the oral epithelium, a modified ba

181 Since tetrazines are important tools to the field of bio

182 disease prevention, detection, and treatment since that time have modified this association.

183 Since that time, RGD has expanded to include a wealth of

184 Since the 1840s, physicians have observed inflammation i

185 e molecular phenomena that have been studied since the 1960s.

186 cohol oxidation by NiOOH has been understood since the 1970s to proceed through a hydrogen atom trans

187 Since the 1970s, however, a significant rising trend in

188 of tree growth from rising air temperatures since the 1970s.

189 inventory has been done by local authorities since the 1990s.

190 s following numerous reverse zoonosis events since the 2009 pandemic.

191 Since the 2012-2013 school year, CVE percentages have in

192 Despite the decrease in ZIKV cases since the 2015-2016 epidemic, questions concerning the p

193 Since the advent of additive manufacturing, known common

194 Since the advent of protein crystallography, atomic-leve

195 reased concentrations of MMP-8 and -9 in GCF since the beginning of pregnancy (P = 0.0381; P = 0.0302

196 these events have been recorded sporadically since the beginning of the 20th century, a systematic ap

197 of experimental research has changed greatly since the Belmont Report.

198 sirable multifunctional effective properties since the best properties of different materials can be

199 Since the birth of biotechnology, hundreds of biotherape

200 Since the Ca(2+) mini-sensor and XIP sequences are also

201 Since the characterization of mRNA in 1961, our understa

202 lish a model of spurge chromosome evolution, since the common paleopolyploid event occurred before th

203 Since the coronoid process provides an insertion site fo

204 In Iceland, since the detection of the first macrolide-resistant iso

205 Since the development of single-hybrid maize breeding pr

206 Risks varied according to the time since the diagnosis of a mental disorder.

207 Since the discovery of functionally competent, energy-co

208 Since the discovery of ocular dominance plasticity, neur

209 Since the discovery of the pioneering bimetallic {MnII4[

210 In the three decades since the discovery of the Wallerian degeneration slow (

211 M) from an indefinite to a 12-month deferral since the donor last had sex with a man.

212 spite extensive studies on mesoporous silica since the early 1990s, the synthesis of two-dimensional

213 cidence has nearly doubled in younger adults since the early 1990s.

214 Since the early 2000s, anti-tumour necrosis factor (TNF)

215 Since the early days of the genome era, the scientific c

216 Since the emergence of deadly pathogens and multidrug-re

217 Since the endogenous ERbeta ligand, 3beta-Adiol, is lost

218 Since the EPR:CR co-activation with hypoxia potentiates

219 anges of ATAAD repair at Stanford University since the establishment of the aortic dissection classif

220 V-2) has spread rapidly throughout the world since the first cases of coronavirus disease 2019 (COVID

221 R-Cas9 gene editing has been eagerly awaited since the first description of the technique in 2013.

222 isease, with each having the chain structure since the first node is one specific SNP (Single Nucleot

223 Since the fluorescent reagent N-(1-pyrene)iodoacetamide

224 odiversity conservation is of key importance since the fungal pathogen Batrachochytrium dendrobatidis

225 on DNA-binding domain expanding in metazoans since the fungi human split.

226 Since the greenhouse gas (GHG) emissions associated with

227 Since the groundbreaking discovery in 2018 that the synt

228 Since the holobiont concept came into the limelight ten

229 Since the improvement of LF patients on facial profile a

230 Since the initial release of miRPathDB, tremendous progr

231 Since the initial report in 2000, metal-ProPhenol cataly

232 Since the interaction between Abeta and fibrinogen incre

233 Since the isolation of morphine from the opium poppy ove

234 om these integrative, multi-omics approaches since the kidney biopsy, blood and urine samples used to

235 aintained if less than 16 weeks have elapsed since the last anti-VEGF injection.

236 ber (SO), making it the most inactive period since the late 1970s.

237 Since the latter are mostly based on quantum chemistry c

238 Since the majority of ASD risk genes are broadly express

239 Accumulated evidence since the mid to late 1990s, however, indicates that low

240 other bacteria hint at additional functions, since the most conserved Y RNA contains a domain that is

241 mained an unresolved enigma in palaeontology since the nineteenth century(2-4).

242 Since the number of bins can be substantially smaller th

243 Since the offspring of smokers are more likely to smoke

244 Since the onset of coronavirus disease 2019, the potenti

245 Since the original description of "dacryadenoma" by Jako

246 ting target IOP, and change in visual acuity since the original trabeculectomy.

247 Since the original work on Bose-Einstein condensation(1,

248 the treatment and had stopped the medication since the past 2 months.

249 Since the phenomenon does not rely on a physical rearran

250 nique opportunities to tune these properties since the pore size and shape can be controlled by the a

251 inty space in phenotype prediction problems, since the probabilistic parameterization of the uncertai

252 Since the publication of that statement, evidence linkin

253 Since the publication of the last American Heart Associa

254 ian 82 years (range: 57-96)) is not critical since the quality of the corneae depends on the number o

255 ely a conserved feature of the metazoan SAC, since the relevant PLK1 and PP2A-B56 binding motifs have

256 Since the start of commercial plastics production in the

257 Since the susceptibility of the human population can be

258 Since the term "empathy" is used to refer to a range of

259 Since the timing of disease is similar in humans and AGM

260 Since the tissue is not disaggregated, the location of c

261 Since the TOP 5-year interim analysis (December 2012), c

262 his release mainly occurs through wastewater since the treatments applied in many wastewater treatmen

263 s when estimating the scaling law parameters since the two types of cities tend to display different

264 Since the ultra-high loading and high-efficiency release

265 Since the value of Target Hazard Quotient was higher tha

266 Since the Yucca Mountain project in the U.S. was defunde

267 onal ensembles of IDPs is of great interest, since their conformational ensembles are the link betwee

268 Since their discovery in 2007(1), much effort has been d

269 the molecular mechanism has remained unknown since their discovery nearly 30 years ago despite the po

270 Since their discovery, giant viruses have expanded our u

271 stem that have preserved primitive materials since their formation approximately 4.6 billion years ag

272 in the field of small fluorocarbon synthesis since their invention in the early 1930s by Thomas Midgl

273 Since then DORA has evolved into an active initiative th

274 Since then, centromeres have been identified in >60 fung

275 Since then, in addition to the four PX existing members

276 Since then, significant evidence has emerged to support

277 Since then, similar enduring effects of early testostero

278 Since then, viperin has been shown to possess activity a

279 Since there is bidirectional transport of BDNF through t

280 n and sensory quality is extremely important since these data may contribute to the launching of new

281 Since these discrepancies could compromise downstream an

282 lenging in the present best CQD solar cells, since these employ a p-type hole-transport layer (HTL) i

283 Since these T cells can influence lytic/latent decisions

284 Solanum cheesmaniae and Solanum galapagense Since these tomatoes grow well despite being constantly

285 cific functional impairments of each subject since these variables can markedly affect therapeutic ef

286 (PTMs) are key events in signal transduction since they affect protein function by regulating their a

287 , current measurement techniques are limited since they are assessed intermittently at non-physiologi

288 on SA synthesis and SA perception pathways, since they are lost in isochorismate synthase1/salicylic

289 have been widely used in rheumatic diseases since they became available over 60 years ago.

290 ial markets in extreme conditions, partially since they disregarded complex interactions within the s

291 Since this case, any patient with severe disease (eg, AR

292 Since this growth-rate dependent regulation of motility

293 Since this nucleic acid fraction originates mainly in ap

294 Score, postgraduate training year, and days since training occurred.

295 d Iran who arrived in Greece as UAMs but had since transitioned into adulthood.

296 onstrated that this pathway is GC-responsive since treating mice with dexamethasone resulted in reduc

297 The effects of age at BCG and time since vaccination were also explored.

298 Since vaccine formulations are given to healthy populati

299 Since water supply was highly correlated with rural resi

300 Since Wigner predicted the dissociation and metallizatio