ライフサイエンスコーパス: single bond

1 ses a highly strained and hindered aryl-aryl single bond.

2 le bond and 0.5 when they are connected by a single bond.

3 to construct the central aryl carbon-carbon single bond.

4 6-, or 7-membered rings are joined by a C-C single bond.

5 r to that for rotation about a carbon-carbon single bond.

6 ntiaromatic fluorenyl cations connected by a single bond.

7 he alpha,beta-carbon=carbon double bond to a single bond.

8 active site that is s-trans about the =C-C=O single bond.

9 city arises from restricted rotation about a single bond.

10 a highly polarized, predominantly ionic Ge-O single bond.

11 pled motion of a double bond and an adjacent single bond.

12 nsaturated radical reactant to insert into a single bond.

13 uction of the barrier to rotation around the single bond.

14 between the two local conformations around a single bond.

15 ron donor and acceptor directly linked via a single bond.

16 the entropy associated with rotation about a single bond.

17 imerize rapidly with the formation of a MnMn single bond.

18 ion and functionalization of a carbon-carbon single bond.

19 ng ligands supporting the five indium-indium single bonds.

20 trogen-naphthalene and the nitrogen-carbonyl single bonds.

21 nvestigation of extremely long carbon-carbon single bonds.

22 he Ga-Ga bonds are significantly weaker than single bonds.

23 mplying that >80% of adhesive events involve single bonds.

24 n extended covalent solid with carbon-oxygen single bonds.

25 retinal) or C12-C13 (11,13-bridged retinal) single bonds.

26 ynes is unaffected by the rotation about the single bonds.

27 defined positions of alternating triple and single bonds.

28 by forming weak and long intermolecular C-C single bonds.

29 the electrophilic reactivity of C-H and C-C single bonds.

30 instead of one of the oxygen atoms with only single bonds.

31 nt four-membered "aromatic" rings linked by "single" bonds.

32 distances near 2.49 A, consistent with Ga-Ga single bonding.

33 xperiments that correlate (1)H and (15)N via single bond (1)J(NH) or multiple bond (2-3)J(NH) couplin

34 torsional angle of 59 degrees and a long C-C single bond (1.60 A) connecting them.

35 )-C(2) bond cleavage/rotation around the N-C single bond/1,6-cyclization" sequence.

36 s significantly affected by "adhesive type" (Single Bond 2 vs experimental antibacterial adhesive p =

37 omplex in this series contains a metal-metal single bond (2.29 A).

38 )(-)](2) show the formation of a Au-Au sigma single bond (2.66 A) in the triplet excimer, compared to

39 ing dehydrogenation in the conversion of the single-bonded 3-phenyl-2H-1,4-benzothiazine dimer 2 to t

40 per manufacturers' instructions, with either Single Bond (3M) or One-Step adhesive (Bisco).

41 The relative percent of Single Bond adhesive was < 50% throughout more than half

42 base model compound which contained only one single bond adjacent to two double bonds, we have found

43 Force-regulated single bonds akin to those of alphabetaTCRs but with mor

44 ar bispentalene cores with large double- and single-bond alternation in the pentalene units, characte

45 eaction-limited detachment rate k(off) for a single bond and also for multiple bonds.

46 nal atoms and an open-shell structure with a single bond and two lone electrons on each terminal atom

47 Surprisingly, a mixture of 10% single bonds and 90% dimeric bonds is sufficient to full

48 iomolecular interactions detected by AFM for single bonds and extend the discussion to multiple bonds

49 ls method, dissect pi effects from the sigma single bonds and lone pair influences.

50 gths of axial and equatorial P-O phosphorane single bonds and P-O single and double bonds in metaphos

51 structure and bonding, the activation of C-C single bonds and, thus, catalytic methods of C-C bond fo

52 eir two amide groups are connected via a N-N single bond, and as a result, these molecules can exist

53 ion (BC), two bonds are sacrificed to form a single bond, and the reaction progress is interrupted at

54 ca. 0.15 A shorter than a conventional Sn-Sn single bond, and the trans-bent structure indicate the p

55 g increasing binding energy from no bonds, a single bond, and two double bond steroids.

56 120 degrees intramolecular rotation around a single bond; another is a molecule capable of repetitive

57 e homolysis and reformation of carbon-carbon single bonds are involved.

58 ity arises from restricted rotation around a single bond, are atropisomers.

59 steroidal skeleton system containing a C3-C9 single bond as well as conditions to selectively ketaliz

60 ered rings separated by alkenes and flexible single bonds as the backbone, rather than conjugated aro

61 wo of the shortest and strongest known Hg-Hg single bonds as the two electronegative CN ligands withd

62 merization followed by rotation around a C-N single bond, as opposed to the more common rotation mech

63 have found that the stretch mode of this C-C single bond at 1232 cm-1 shifts up by 15 cm-1 and its in

64 uble bond with concomitant introduction of a single bond at C-11 piperidine resulted in compound 3 th

65 ow transition-metal-mediated cleavage of C-C single bonds at either the core or the periphery of synt

66 Single bond attachments between spacers and glycoluril m

67 the absence of singular stereogenic atoms or single bond axes of chirality.

68 S) with ~4.8 angstrom spatial resolution and single bond (B-O) sensitivity.

69 nsforms into a triplet biradical bearing one single bond between the addends.

70 is in part a result of the introduction of a single bond between the C2' and C6 carbon atoms of cis-r

71 to measure the force-dependent lifetimes of single bonds between a fibronectin fragment and an integ

72 Single bonds between carbon atoms are inherently challen

73 The kinetic parameters of single bonds between neural cell adhesion molecules were

74 which the C(60)O moieties are linked by two single bonds between sp(3)-hybridized carbon atoms adjac

75 trates, which exhibit two or three rotatable single bonds between the binding site and the reactive o

76 f single-molecule technologies, ranging from single bond breaking to complex chaperone machinery, alo

77 ater efficiency than for comparable cases of single bond breaking.

78 ighly distorted cavity, where the additional single-bond bridge imposes an extreme internal strain on

79 e experimentally indistinguishable from true single bonds, but which have considerable effects on the

80 The variability of carbon-carbon single bonds by steric and electronic effects is probed

81 h molecules, the activation of carbon-carbon single bonds (C-C bonds) in simple substrates is strateg

82 iants of HO-:C-OH contains two very short CO single bonds (ca. 1.32 A).

83 bis(boratabenzene) moiety with a boron-boron single bond can be viewed as a symmetric dimer of the pa

84 Transition-metal-mediated cleavage of C-C single bonds can enable entirely new retrosynthetic disc

85 are built of a previously unobserved anionic single-bonded carbon-nitrogen three-dimensional (3D) fra

86 trace the origin of the effect to increased single bond character for the C(carbonyl)-N bond due to

87 Here, we adapt recently developed single-bond chemistry techniques to study individual dis

88 fficiency of fragmentation was observed with single bond cleavage of alcohols and in six-member ring

89 reported from 1987 to 2019 that exploit C-C single bond cleavage of cyclopropylamine-based systems.

90 spects of key methodologies that exploit C-C single-bond cleavage of strained ring systems are highli

91 Analogous exchange reactions with the single-bonded (CO)(3)CpMo-MoCp(CO)(3) gave ArM-MoCp(CO)(

92 imum for Sn-Sn, is a relatively closed-shell single-bond configuration where LP and LP are nominally

93 consists of a 120 degrees rotation around a single bond connecting a three-bladed subunit to the bul

94 d that the conformation of the retinal C6-C7 single bond connecting the beta-ionone ring and the reti

95 tinuity of the pai delocalization at the C-C single bonds connecting the central six-membered rings t

96 h decreasing solvent viscosity, suggesting a single-bond decomposition mechanism.

97 rmational stability of the A1 domain and the single bond dissociation kinetics of the A1-GPIbalpha in

98 e fairly short, average 1.7 A, relative to a single bond distance of approximately 1.8 A and are coor

99 iently long-lived to rotate around the C2-C3 single bond during catalysis.

100 denote as TMA-OH2, containing a stable Al-O single bond emerged as the building block molecule.

101 res and alkenes separated by freely rotating single bonds, endowing it with a large bandgap of ~5 eV

102 kcal/mol binding energy, akin to typical M-M single-bond energies.

103 rom the 70 pN force quantum, we estimate the single bond energy to be approximately 4-5 kJ/mol, in re

104 atalytic process from the perspective of the single-bond energy using high-resolution scanning tunnel

105 CD44v-HA and CD44s-HA single bonds exhibit similar kinetic and micromechanical

106 n constants for L-selectin and P-selectin at single bond forces above 125 pN were considerably lower

107 At estimated single bond forces of 125 pN and below, all three select

108 addressin (PNAd) were compared at estimated single bond forces ranging from 37 to 250 pN.

109 ical binding probability on the detection of single-bond forces are examined systematically.

110 e crucial role of the initial reversible C-C single bond formation for the synthesis of crystalline 2

111 oranes, 9-BBN and Ph3 B, provide facile B-B' single bond formation.

112 measure the association and dissociation of single bonds formed between microsphere-bound CD16 antig

113 e data at different loading rates, using the single-bond full microscopic model, indicates that the b

114 eric nitrogen (cg-PN) with nitrogen-nitrogen single bonds has been synthesized together with a relate

115 by selective reduction of the triple bond to single bond have been utilized as the decisive steps to

116 ous 360 degrees directional rotation about a single bond have proved elusive, with previous designs l

117 deed only two complexes with thorium-arsenic single bonds have been structurally authenticated, refle

118 d cationic carbenes are known to insert into single bonds; however, this is the first observation of

119 C(sp(3))-O bonds, and the formation of three single bonds (i.e., exo-, endo-, and C-glycosidic bonds)

120 gy barrier for rotation around the aryl-aryl single bond in 3 is 31 kcal/mol.

121 .24 A, both of which indicate an iron-oxygen single bond in a ferryl-hydroxide, Fe(IV)OH, moiety.

122 demonstrate that the very small change of a single bond in CNC to a double bond in CeNC causes signi

123 As a result, the strongest single bond in organic chemistry can now be selectively

124 ange of a sulfur to an oxygen, scission of a single bond in P2'-cyclopropylaminobenzothiazole (or -ox

125 tional isomerization about the carbon-carbon single bond in simple ethane derivatives in room-tempera

126 of restricted rotation around Csp(3)-Csp(2) single bond in some tetrahydronaphthalene cycloadducts h

127 rom epsilonA by change of a double bond to a single bond in the 5-member exocyclic ring and are forme

128 double bond in 7-norbornenylidene (1) by the single bond in the endo-fused cyclopropane unit of carbe

129 We show how destabilization of a single bond in the front-runner product averts its forma

130 rier for rotation around the carbon-nitrogen single bond in the tetrahedral intermediate derived from

131 n enzyme VlmB in a reaction in which the N-N single bond in the VlmO/ForJ product is oxidized by four

132 eworks by the formation of new carbon-carbon single bonds in a regio- and stereoselective manner.

133 ovo enzyme templates for the cleavage of C-C single bonds in long-chain hydrocarbons, we analyzed pro

134 The C-F bond is one of the strongest single bonds in nature.

135 nes to their corresponding formal double and single bonds in nonaromatic systems.

136 Carbon-fluorine bonds are the strongest single bonds in organic chemistry, making activation and

137 are outside the range (2.88-2.97 A) of Tl-Tl single bonds in R(2)TlTlR(2) compounds.

138 The rearrangement of carbon-carbon (C-C) single bonds in readily available carbocyclic scaffolds

139 breach into the range of extremely stretched single bonds in terms of bond distances and binding ener

140 ncerted isomerization of C9'-C8' and C7'-C6' single bonds in the bicycle-pedal (s-BP) manner and stru

141 -rod conjugated polymers that do not contain single bonds in the main chain is reported.

142 hat the number of cis double bonds and s-cis single bonds in the polyene chain determine the topology

143 of transition-metal-mediated cleavage of C-C single bonds in total synthesis can be ascribed to a com

144 ectrons to the di-gallium unit to generate a single bond (in addition to the weak interaction in the

145 the polarity of the solvent, either complete single bond (in DMSO) or double bond (in cyclohexane) ro

146 d to the macrocyclic core structure by a C-C single bond, in place of the synthetically more demandin

147 The correlation and comparison with aryne single bond insertion chemistry will be discussed.

148 biomembrane force probe capable of measuring single bond interactions, we showed ICAM-1 binding to LF

149 omplexes (s-, d- and f-block) in which a C-C single bond interacts with a metal centre are discussed:

150 ysis of two covalent bonds, occurs through a single-bond intermediate.

151 bstituent and linked via three carbon-carbon single bonds into a three-dimensional random network of

152 ent nitrogen atoms that are connected with a single bond is highly structure dependent.

153 The catalytic cleavage of two C-C single bonds is achieved by treatment of the hydrocarbon

154 ization of unactivated carbon-hydrogen (C-H) single bonds is an efficient strategy for rapid generati

155 etathesis of kinetically less accessible C-C single bonds is extremely rare.

156 gher mechanical forces; thus, the rupture of single bonds is preferred over the rupture of double or

157 of molecules by cleaving inert carbon-carbon single bonds is regarded as a great synthetic challenge

158 r the activation of unstrained carbon-carbon single bonds is still limited.

159 ion FTIR and UV/Vis spectroscopy support the single bond isomerization of the carotenoid in the s-BP

160 pane carboxaldehyde above the barrier to C-C single-bond isomerization, we applied line-shape analysi

161 bridge-acceptor torsional motions about the single bonds joining them.

162 model is comparable to the binding energy of single bond ketone steroids.

163 monstrating the impact of force history with single-bond kinetic experiments involving selectins and

164 ocyte interface measured in probe tests with single-bond kinetics and the kinetics of cytoskeletal di

165 at longer bond lengths than their respective single bond lengths or their separations in (calculated)

166 Our work at the single bond level directly demonstrates that thiol/disul

167 der high voltage bias at the single molecule/single bond level using the scanning tunneling microscop

168 stry of binding with atomic precision at the single-bond level and tunable control over the binding c

169 d bond formation and characterization at the single-bond level probe chemistry at the spatial limit.

170 aking and formation of chemical bonds at the single-bond level, especially during catalytic reactions

171 chamber system mirrored the force-dependent single-bond lifetimes.

172 inside-out and outside-in signaling exhibit single-bond-like statistics for dissociation under force

173 The study of the reaction process at the single-bond limit is the key to understanding the cataly

174 he result of the rotation around the pivotal single bond linking two planar frameworks.

175 conjugated polymers that do not contain any single bonds linking monomer units along the backbone bu

176 inspire the development of more general C-C single-bond metathesis and orthogonal cross-coupling rea

177 report a ruthenium-catalysed reversible C-C single-bond metathesis reaction that allows redox- and p

178 monstrate the untapped potential of emerging single-bond metathesis reactions in the preparation of n

179 e regressed Bell parameters (consistent with single bond Monte Carlo simulation) were zero-stress off

180 fragmentation patterns at the carbon-carbon single bonds neighboring the double bonds.

181 ced energy barrier to rotation about the C-C single bonds next to either a trans or cis carbon double

182 xample of a material containing branched all-single-bonded nitrogen chains [N(5) (5-) ]( ) .

183 The rotational freedom of the carbon-carbon single bonds of 1,2-disubstituted ethanes affords the po

184 discriminating between the enantiotopic C-O single bonds of a gem-diacetate.

185 accommodated by a model in which many of the single bonds of suramin are unrestricted at room tempera

186 are not compatible with a model in which the single bonds of the linker are completely restricted whe

187 is observed and this suggests torsion around single bonds of the retinylidene chromophore.

188 sion is across the C(2)-C(3) cyclopentadiene single bond, only a single benzene is needed to bind an

189 ed either by bond reforming in the case of a single bond or by asynchronized rupture of multiple indi

190 display an alternating triple and very short single bond pattern, with the degree of bond alternation

191 TCR/pMHC couples in a cell-free system with single bond resolution.

192 ntact atomic force microscopy, we imaged the single-bond-resolved chemical structure of transient met

193 rbon--carbon double bonds and carbon--carbon single bonds, respectively.

194 g-zag lattice direction mediated either by a single bond rotation or through the loss of two carbon a

195 precedented photoreaction, a one-photon dual single-bond rotation.

196 of conformational entropy due to freezing of single bond rotations and the favorable burial of the hy

197 emical Hula-Twist isomerizations and thermal single-bond rotations.

198 By extending the single-bond rupture analysis to a multibond system of n

199 Experiments yielded median single-bond rupture forces from 25 to 44 pN for IgG from

200 Average single-bond rupture forces of -0.95 +/- 0.04 nN were obs

201 e tip and substrate and allows estimation of single-bond rupture forces.

202 ineralized, dehydrated, and infiltrated with Single Bond (SB) adhesive under optimum conditions; the

203 By virtue of the single-bond sensitivity of UHV-TERS to oxygen adatoms, w

204 with adjacent nitrogen atoms connected by a single bond should be abandoned.

205 ns linked to the outside of the complex by a single bond showed no inhibition whatsoever at any conce

206 A single bonding site for the iridium is identified on the

207 This single bond switch provides the peptides with a weak hel

208 t undergoes reversible activation of the C-C single bond that interacts with the metal center, establ

209 In effect, vibrational energy localized in single bonds that are critical for the reaction is redis

210 rmation of strongly stabilized localized O-O single bonds that explain the energy penalty required to

211 thus transforming all C=C double bonds into single bonds, the stability of the LiF inside was reduce

212 s of atropisomerism around C(sp(2))-C(sp(3)) single bonds through theoretical calculations.

213 to silicon quantum dots from a carbon-carbon single bond to a double bond, we access a strong couplin

214 The heme is linked to this protein through a single bond to the 1-methyl group.

215 arbon-fluorine bonds are the strongest known single bonds to carbon and as a consequence can prove ve

216 l motions within the cavity, implicating the single-bond torsion as an important contributor to inter

217 eight of rotational barriers around formally single bonds, UV-vis spectra and electrochemical behavio

218 Despite significant advances in forging a single bond via C-H activation in the past decade, one-s

219 double bond transformation to a Ti(3+)-O(1-) single bond via the individual atomic displacements of t

220 approximately 0.6 kcal/mol, equivalent to a single bond vibration).

221 e lifetimes near 10(-13) sec, the time for a single bond vibration.

222 Monte Carlo simulation indicates that only a single bond was probably involved in every adhesion even

223 As such, several thorium-oxygen single bonds were synthesized for comparison, including

224 consisting of three or more rotors linked by single bonds, whereby the two terminal rotors are static

225 nor and acceptor moieties are connected by a single bond, which could potentially be replaced by a fu

226 nto two or more fragments at central acyclic single bonds, while removing any core fragment structura

227 ying micromechanical properties adhered by a single bond with a constant kinetic off-rate.

228 ated to those of the corresponding CH3-XHn+1 single bonds with a slope of 2.5.

229 with benzenoid structures, which form ring-M single bonds with X = CN, CO2Me, CHO, C3HMeBF2O2, and NO

230 nd order from 2 to a value consistent with a single bond, with a concomitant change in the formal ura

231 is the primary determinant of cleavage of a single bond within the 5 nt strand of the internal loop.

232 ladium-catalyzed activation of carbon-carbon single bonds within triarylmethanols has led to a greate

233 eling, an initial phase is proposed in which single-bonded "Y-ladder" polymers rapidly elongate befor