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1 DNA helicase), or RPA2 (a protein that binds single-stranded DNA).
2 ry likely to lower the affinity of SSBP1 for single-strand DNA.
3 rogression, resulting in the accumulation of single stranded DNA.
4 cific (HMCES) as a sensor of abasic sites in single-stranded DNA.
5 ish this task, RAD51 must be loaded onto the single-stranded DNA.
6 hnique centered around the directionality of single-stranded DNA.
7 s comprise an RNA/DNA hybrid and a displaced single-stranded DNA.
8 ation of transcription from both double- and single-stranded DNA.
9 TPase that forms a nucleoprotein filament on single-stranded DNA.
10 by facilitating RAD51 filament formation on single-stranded DNA.
11 -methyladenine is preferentially repaired in single-stranded DNA.
12 omoting error-free repair of abasic sites in single-stranded DNA.
13 NA efficiently integrates into the genome as single-stranded DNA, (2) that the resulting heteroduplex
15 on associated with increased accumulation of single-stranded DNA, a substrate of APOBEC3A, triggering
17 ed through pH-assisted thiol-gold bonding of single stranded DNA and salt aging, with preconjugated b
18 telomeric G-quadruplex DNA to complementary single stranded DNA and to telomere binding protein POT1
19 RPA-like complex that associates with G-rich single-strand DNA and helps resolve replication problems
20 le-stranded DNA-binding proteins (SSBs) bind single-stranded DNA and help to recruit heterologous pro
22 e Pif1, which tracks in a 5'-3' direction on single-stranded DNA and plays a role in genome maintenan
23 lyzed, radical reaction process that cleaves single-stranded DNA and requires only redox-inactive met
24 nzymes, dimerization enables processivity on single-stranded DNA and results in higher levels of muta
25 f iminosulfur oxydifluorides to amine-tagged single-stranded DNA and to BSA protein demonstrate the p
26 BV DNA polymerase inhibitor, at the stage of single-stranded DNA and was followed by removal of PFA t
27 tional R-loops (RNA/DNA duplex and displaced single-stranded DNA) and DNA double-strand breaks (DSBs)
28 ES acts at replication forks, binds PCNA and single-stranded DNA, and generates a DNA-protein crossli
29 NA) could be used as a magnified analogue of single-stranded DNA, and that two meta-DNAs that contain
30 bustly with specific sequences of unmodified single-stranded DNA, and we have identified five tags th
32 ted to a handful of microorganisms for which single-stranded DNA-annealing proteins (SSAPs) that prom
37 es comprising a DNA:RNA hybrid and displaced single-stranded DNA, are important drivers of damage ari
39 Here the authors show that APOBEC3G binds single-stranded DNA as an active deaminase monomer, subs
42 We propose that the presence of persistent single-stranded DNA, as a consequence of transcription-r
43 nthetic sequence that mimics freshly unwound single-stranded DNA at replication fork showed that RPA
45 can covalently cross-link to abasic sites in single-stranded DNA at stalled replication forks to prev
46 ving deoxyribozymes (DNAzymes) are synthetic single-stranded DNA-based catalytic molecules that can b
52 t are unable to form t-loops or complex with single-strand DNA binding proteins, raising the question
54 when recombinantly expressed had the general single-stranded DNA binding activity of RPA complexes, u
56 hannel in hPIF1 that we show is critical for single-stranded DNA binding during unwinding, but not th
57 ralogous to the large subunit of the general single-stranded DNA binding heterotrimer replication pro
59 lambda Orf, a protein that binds to E. coli single-stranded DNA binding protein (SSB) to function as
61 The nascent DNA colocalized with the VACV single-stranded DNA binding protein I3 in multiple punct
62 hairpin RNA (shRNA) screening, we identified single-stranded DNA binding protein replication protein
63 factor IIH prevented the accumulation of the single-stranded DNA binding protein replication protein
64 with the in vivo occupancy of mitochondrial single-stranded DNA binding protein reported previously
65 n replication protein A and Escherichia coli single-stranded DNA binding protein that the magnitude o
66 ivity, which is alleviated by binding of the single-stranded DNA binding protein, RPA, to the exclude
71 CST (CTC1-STN1-TEN1) proteins, which form a single-stranded DNA-binding complex, localize at stalled
72 on between Escherichia coli RNase HI and the single-stranded DNA-binding protein (SSB) in this proces
74 o investigate the prion-forming potential of single-stranded DNA-binding protein (SSB) of Campylobact
75 of core subunits of LMO2 and LDB1 as well as single-stranded DNA-binding protein (SSBP) cofactors and
76 The Chip/LIM-domain binding protein (LDB)-single-stranded DNA-binding protein (SSDP) (ChiLS) compl
77 1) transcription factor and the co-regulator single-stranded DNA-binding protein 3 (SSBP3) regulates
78 ethods, this amplification requires only the single-stranded DNA-binding protein gp32 from bacterioph
79 overcome by the DNA-binding activity of the single-stranded DNA-binding protein RPA, efficient DNA r
80 nal proteins, including the telomeric repeat single-stranded DNA-binding protein Teb1 and its heterot
82 107Q amino acid changes in the mitochondrial single-stranded DNA-binding protein, a crucial protein i
85 d of telomeric sequence-specific double- and single-stranded DNA-binding proteins, Taz1 and Pot1, res
87 ic target sites and report that simultaneous single-stranded DNA break formation at donor and accepto
90 measure the kinetics of translocation along single-stranded DNA by the helicase Hel308 from Thermoco
91 aN substrates modified with thiolated ssDNA (single stranded DNA) can be successfully used in the ana
93 slocates sequentially hand-over-hand along a single-stranded DNA coil, akin to the way AAA+ ATPases (
94 oligonucleotide-based FISH probes with long, single-stranded DNA concatemers that aggregate a multitu
95 nt R-loops (RNA-DNA hybrids with a displaced single-stranded DNA) create DNA damage and lead to genom
96 J and RAP80 exposed to MMC are attributed to single-stranded DNA created by Mre11 and CtIP nucleases.
97 s, as well as numerous circular Rep-encoding single-stranded DNA (CRESS DNA) viral genomes, were iden
98 e, and Iflaviridae and circular Rep-encoding single-stranded DNA (CRESS-DNA) virus, were also detecte
101 ate immune response is the APOBEC3 family of single-stranded DNA cytosine deaminases, which inhibits
103 erfacial potential changes were measured for single-stranded DNA detection with an unprecedented zept
105 -CRISPR), a targeting strategy in which long single-stranded DNA donors are injected with pre-assembl
107 A double-strand breaks (DSBs) to generate 3'-single-stranded DNA facilitates DSB repair via error-fre
108 ki2-like nucleic acid helicase that provides single-stranded DNA for alkylation damage repair by the
109 DNA excision by Exo1, which causes increased single-strand DNA formation, RPA exhaustion, DNA breaks,
110 E2Ct, fail to induce RPA phosphorylation and single-stranded DNA formation, leading to defects in PCN
111 The separation and partitioning of large single-stranded DNA fragments of the homologous chromoso
112 We demonstrated that Brca2 protein prevents single-stranded DNA gap accumulation at replication fork
113 nthesis downstream of the lesion, creating a single-stranded DNA gap that is repaired primarily in an
114 tions arise through the aberrant repair of a single-stranded DNA gap, in a process that is dependent
118 vely charged DNA binding protein J guide the single-stranded DNA genome into the icosahedral capsid.
119 tructures of Pf4 with and without its linear single-stranded DNA genome, and studied Pf4 assembly int
120 are structurally simple viruses with linear single-stranded DNA genomes and nonenveloped icosahedral
121 geminiviruses (plant viruses with circular, single-stranded DNA genomes) are the major group of emer
123 determine how they contribute to duplex and single-stranded DNA handling, and test the cellular cons
124 vimetric analytical techniques, we find that single-stranded DNA has a significant flame-retardant ef
125 ded binding proteins both protect and expose single-stranded DNA has important implications for our u
126 an essential replisome component that binds single-stranded DNA, has a role in replication-coupled n
127 trol the translocation speed of helicases on single-stranded DNA, however the cause of these effects
128 They exhibit 5' exonuclease activity on single-stranded DNA, hydrolyzing it at the acidic pH ass
129 which long distance binding (25 angstrom) of single-stranded DNA in an allosteric site primes the act
131 unequivocally establishes the existence of a single-stranded DNA incorporation pathway in human cells
134 nded sites and also at AT-rich regions where single-stranded DNA is exposed during origin opening.
135 sversion substitutions; results suggest that single-stranded DNA is formed during the genesis of the
136 ude that ROS contribute to TLD by converting single-stranded DNA lesions into double-stranded DNA bre
137 o three hexanucleotide repeats resulted in a single-stranded DNA-like mechanical behavior under all c
138 NA hybridized to the complementary DNA and a single-stranded DNA loop, are formed in switch regions o
139 molecular Fe(II)(4)L(4) tetrahedron binds to single stranded DNA, mismatched DNA base pairs, and thre
141 pose that these contigs correspond to linear single-stranded DNA molecules that fold onto themselves
142 our analysis to study the kinetics of human single-strand DNA nuclease TREX2, DNA polymerases, RNA,
143 olecule arrays by electrostatically adhering single-stranded DNA of gene-like length onto positively
144 ce receptor of interest is conjugated with a single-stranded DNA oligonucleotide, which hybridizes to
146 application for precise genome editing using single strand DNA oligonucleotides and show that an effi
148 and diffusion constants of several different single-stranded DNA oligonucleotides trapped in an MspA
152 In this regard, aptamers, as artificial single-stranded DNA or RNA oligonucleotides with catalyt
154 choice is determined by the generation of 3 single-strand DNA overhangs at the break that are initia
156 nvolves introducing multiple, short pairs of single-stranded DNA overhangs to components of the struc
158 fficient covalent immobilization of purified single-stranded DNA probe oligomers on cleaned gold micr
160 nthesized oligonucleotides or amplicon-based single-stranded DNA probes and validated the technique o
161 relies on the immobilization on a surface of single-stranded DNA probes that bind complementary targe
162 or annealing activities limit the amount of single-stranded DNA product that Pif1 can generate, lead
163 nd that the Cas4-Cas1-Cas2 complex processes single-stranded DNA provided in cis or in trans with a d
165 egrases innovated from double-strand- toward single-strand-DNA recombination through the acquisition
167 ine starvation leads to accumulation of both single-stranded DNA regions and intracellular ROS, and i
168 ination with paper-based electrodes, using a single strand DNA relative to H1047R (A3140G) missense m
169 ocesses after cisplatin treatment, including single-strand DNA repair and Fanconi anemia pathways, su
170 ivery of CRISPR/Cpf1 ribonucleoproteins with single-stranded DNA repair templates results in precise
171 stranded MLPA products and subsequently to a single stranded DNA reporter probe bearing a HRP molecul
172 d complex thereafter nonspecifically cleaves single-stranded DNA reporter probes labeled with a fluor
173 ng of layered rGO and rGO/gold nanoparticles/single stranded DNA (rGO/AuNPs/ssDNA) composites over PE
175 nduced by CRISPR/Cas9, as well as individual single-strand DNA scissions induced by the nickase versi
176 lthough a UvrD monomer can translocate along single-stranded DNA, self-assembly or interaction with a
179 eavage can be rapidly digested by a 3' to 5' single-stranded DNA-specific exonuclease, indicating Cas
180 educed graphene oxide aerogel labeled with a single strand DNA (ss-HSDNA/rGOae) modified on a rotatin
181 de experimental evidence that ComFA binds to single stranded DNA (ssDNA) and has ssDNA-dependent ATPa
183 ine nucleotides, generating deoxyuridine, in single stranded DNA (ssDNA) intermediates produced durin
184 ipment and facilitates the immobilization of single stranded DNA (ssDNA) probe sequences on a wide va
185 becomes activated and degrades a fluorescent single stranded DNA (ssDNA) reporter present in the assa
186 hanistic understanding of Sgs1 activities on single stranded DNA (ssDNA), which is a central intermed
189 red in several cancer genomes were linked to single-strand DNA (ssDNA) intermediates in various proce
190 lex DNAs before and after cleavage of the 5' single-strand DNA (ssDNA) tail by the AdnA nuclease.
191 one Zf-GRF motif mediating interaction with single-strand DNA (ssDNA), whereas the major AP endonucl
192 eation rate of ScDmc1 results from its lower single-stranded DNA (ssDNA) affinity, compared to that o
194 ate-free synthesis of high-molecular-weight, single-stranded DNA (ssDNA) and demonstrate that it proc
195 by hyperphosphorylation of RPA, a sensor of single-stranded DNA (ssDNA) and DNA replication stress.
197 nnealase, a protein that binds complementary single-stranded DNA (ssDNA) and facilitates its annealin
198 A orchestrates these processes by binding to single-stranded DNA (ssDNA) and interacting with several
200 he AID/APOBEC enzymes deaminate cytosines in single-stranded DNA (ssDNA) and play key roles in innate
202 replication by excising oxidized bases from single-stranded DNA (ssDNA) and unhooking interstrand cr
203 ere, three different methods that can detect single-stranded DNA (ssDNA) are utilized to identify the
205 loading of Redbeta directly onto the initial single-stranded DNA (ssDNA) at a 3'-overhang, and second
206 The XPA protein functions together with the single-stranded DNA (ssDNA) binding protein RPA as the c
207 d-specific excision that begins at a distant single-stranded DNA (ssDNA) break and proceeds back past
208 ing that Exo1 can digest a randomly selected single-stranded DNA (ssDNA) but not a poly(dT) oligonucl
209 hemically, human RAD51 polymerises faster on single-stranded DNA (ssDNA) compared to double-stranded
213 atalytic polypeptide-like (APOBEC) family of single-stranded DNA (ssDNA) cytosine deaminases provides
214 iency virus type 1 (HIV-1) infectivity, is a single-stranded DNA (ssDNA) deoxycytidine deaminase with
215 luorescent sensor array made of aptamers and single-stranded DNA (ssDNA) dyes for multiplexed detecti
216 f a DSB, controlling the formation of the 3' single-stranded DNA (ssDNA) filament needed for recombin
217 through the cell cytoplasm, and deliver the single-stranded DNA (ssDNA) genome to the nucleus, where
219 dimeric protein that potentially binds with single-stranded DNA (ssDNA) in a manner similar to human
220 n is a highly dynamic process that generates single-stranded DNA (ssDNA) in the genome as 'transcript
222 induces the generation of large stretches of single-stranded DNA (ssDNA) intermediates that are rapid
223 mportant DNA metabolic events by stabilizing single-stranded DNA (ssDNA) intermediates, activating th
226 coupled with a gold substrate can resolve a single-stranded DNA (ssDNA) molecule with a spatial reso
229 epsilon has greater contact with the nascent single-stranded DNA (ssDNA) of the leading strand on act
230 nds of linear chromosomes and terminate in a single-stranded DNA (ssDNA) overhang recognized by POT1-
232 In the marine environment, only a few lytic single-stranded DNA (ssDNA) phages have been isolated an
233 in models containing up to 1-kb inserts when single-stranded DNA (ssDNA) repair templates are supplie
235 ceeds via binding of RPA, RAD51, and DMC1 to single-stranded DNA (ssDNA) substrates created after for
236 often begins with creation of initiating 3' single-stranded DNA (ssDNA) tails on each side of a doub
239 tly, we find no evidence for BLM activity on single-stranded DNA (ssDNA) that is bound by replication
240 and lagging strands leads to accumulation of single-stranded DNA (ssDNA) that promotes mutation.
242 helicase activity, ScPif1 is also known as a single-stranded DNA (ssDNA) translocase, while how ScPif
244 tion and genomic substitution rates, RNA and single-stranded DNA (ssDNA) viruses may be important con
246 gle-stranded DNA binding protein (SSB) wraps single-stranded DNA (ssDNA) with high affinity to protec
249 ate containing RNA:DNA hybrids and displaced single-stranded DNA (ssDNA), has emerged as a major sour
250 t of DNA-RNA hybridization and the displaced single-stranded DNA (ssDNA), have been identified in bac
251 ) for the label-free electrical detection of single-stranded DNA (ssDNA), in-solution- and on-chip-hy
252 on of the DNA damage signal, accumulation of single-stranded DNA (ssDNA), sensitivity to replication
253 ins engineered for large-scale production of single-stranded DNA (ssDNA), we probed the substrate spe
254 py structure of human CST bound to telomeric single-stranded DNA (ssDNA), which assembles as a decame
255 sitive coactivator of transcription (PC4), a single-stranded DNA (ssDNA)-binding protein, as a novel
259 is a bifunctional enzyme that contains both single-stranded DNA (ssDNA)-specific nuclease and motor
266 PF and ERCC-XPF and show that the binding to single-stranded DNA (ssDNA)/dsDNA junctions is dependent
267 SCNT decreased in order with the binding of single-stranded DNA (SSDNA, probe DNA) and double-strand
268 ch is able to detect hybridization of probe (single stranded DNA-ssDNA) and hybrid (double stranded D
270 , AddAB or AdnAB) generates the requisite 3' single-strand DNA substrate for RecA-mediated strand inv
272 esection of broken ends to generate long, 3' single-stranded DNA tails, annealing of complementary se
273 ial signal was generated by hybridization of single stranded DNA targets to immobilized recognition p
274 gents, to prime second strand synthesis of a single-stranded DNA template and generate millions of pa
275 he absence of dNTPs, this leads to excessive single-strand DNA that exceeds the protective capacity o
276 res formed by an RNA:DNA hybrid and unpaired single-stranded DNA that represent a source of genomic i
278 rial strategies (1) , especially small lytic single-stranded DNA (the microviruses) and RNA phages (t
281 OBEC3A, an enzyme that converts cytosines in single-stranded DNA to uracil, and mutations in a variet
283 hannel of the N-tier and the unwound leading single-strand DNA traverses the channel through the N-ti
284 the entropy associated with straightening of single-strand DNA upon nucleoprotein filament formation.
285 In the case of the ubiquitous human circular single-stranded DNA virus family Anelloviridae, there is
286 s endocytose Pf, and internalization of this single-stranded DNA virus results in phage RNA productio
287 ) and Minute Virus of Mice (MVM), both T = 1 single stranded DNA viruses, and Bromo Mosaic Virus (BMV
290 19) uncover a previously undefined family of single-stranded DNA viruses, Redondoviridae, in human or
293 ore, the measurements of thermally denatured single-stranded DNA were carried out and the value of (G
295 an entry site for Exo1 in vitro to generate single-stranded DNA, which would be susceptible to both
296 eir destinations allows for a simple robot a single-stranded DNA with one leg and two foot domains fo
298 for deaminating cytosine bases to uracil in single-stranded DNA, with characteristic sequence prefer
299 Here, we present a study of surfactant and single-stranded DNA-wrapped SWNTs suspended in aqueous s
300 A Polymerase Cofactor), preferentially binds single-stranded DNA, yet contains a structural fold dist