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1 DNA helicase), or RPA2 (a protein that binds single-stranded DNA).
2 rogression, resulting in the accumulation of single stranded DNA.
3 cific (HMCES) as a sensor of abasic sites in single-stranded DNA.
4 ish this task, RAD51 must be loaded onto the single-stranded DNA.
5 hnique centered around the directionality of single-stranded DNA.
6 s comprise an RNA/DNA hybrid and a displaced single-stranded DNA.
7 ation of transcription from both double- and single-stranded DNA.
8 TPase that forms a nucleoprotein filament on single-stranded DNA.
9 First, we modified a glass surface with single-stranded DNA.
10 by facilitating RAD51 filament formation on single-stranded DNA.
11 -methyladenine is preferentially repaired in single-stranded DNA.
12 omoting error-free repair of abasic sites in single-stranded DNA.
13 NA efficiently integrates into the genome as single-stranded DNA, (2) that the resulting heteroduplex
15 on associated with increased accumulation of single-stranded DNA, a substrate of APOBEC3A, triggering
18 ed through pH-assisted thiol-gold bonding of single stranded DNA and salt aging, with preconjugated b
19 telomeric G-quadruplex DNA to complementary single stranded DNA and to telomere binding protein POT1
20 le-stranded DNA-binding proteins (SSBs) bind single-stranded DNA and help to recruit heterologous pro
22 e Pif1, which tracks in a 5'-3' direction on single-stranded DNA and plays a role in genome maintenan
23 lyzed, radical reaction process that cleaves single-stranded DNA and requires only redox-inactive met
24 nzymes, dimerization enables processivity on single-stranded DNA and results in higher levels of muta
25 f iminosulfur oxydifluorides to amine-tagged single-stranded DNA and to BSA protein demonstrate the p
26 BV DNA polymerase inhibitor, at the stage of single-stranded DNA and was followed by removal of PFA t
27 tional R-loops (RNA/DNA duplex and displaced single-stranded DNA) and DNA double-strand breaks (DSBs)
28 ES acts at replication forks, binds PCNA and single-stranded DNA, and generates a DNA-protein crossli
29 NA) could be used as a magnified analogue of single-stranded DNA, and that two meta-DNAs that contain
30 bustly with specific sequences of unmodified single-stranded DNA, and we have identified five tags th
31 ted to a handful of microorganisms for which single-stranded DNA-annealing proteins (SSAPs) that prom
34 exed, expanded proteomic technique that uses single-stranded DNA aptamers to assay 4783 human protein
37 es comprising a DNA:RNA hybrid and displaced single-stranded DNA, are important drivers of damage ari
39 Here the authors show that APOBEC3G binds single-stranded DNA as an active deaminase monomer, subs
42 We propose that the presence of persistent single-stranded DNA, as a consequence of transcription-r
43 nthetic sequence that mimics freshly unwound single-stranded DNA at replication fork showed that RPA
45 can covalently cross-link to abasic sites in single-stranded DNA at stalled replication forks to prev
46 ving deoxyribozymes (DNAzymes) are synthetic single-stranded DNA-based catalytic molecules that can b
49 when recombinantly expressed had the general single-stranded DNA binding activity of RPA complexes, u
51 hannel in hPIF1 that we show is critical for single-stranded DNA binding during unwinding, but not th
52 ralogous to the large subunit of the general single-stranded DNA binding heterotrimer replication pro
55 lambda Orf, a protein that binds to E. coli single-stranded DNA binding protein (SSB) to function as
57 The nascent DNA colocalized with the VACV single-stranded DNA binding protein I3 in multiple punct
59 hairpin RNA (shRNA) screening, we identified single-stranded DNA binding protein replication protein
60 factor IIH prevented the accumulation of the single-stranded DNA binding protein replication protein
61 with the in vivo occupancy of mitochondrial single-stranded DNA binding protein reported previously
62 n replication protein A and Escherichia coli single-stranded DNA binding protein that the magnitude o
63 ivity, which is alleviated by binding of the single-stranded DNA binding protein, RPA, to the exclude
70 CST (CTC1-STN1-TEN1) proteins, which form a single-stranded DNA-binding complex, localize at stalled
71 on between Escherichia coli RNase HI and the single-stranded DNA-binding protein (SSB) in this proces
73 o investigate the prion-forming potential of single-stranded DNA-binding protein (SSB) of Campylobact
74 of core subunits of LMO2 and LDB1 as well as single-stranded DNA-binding protein (SSBP) cofactors and
75 The Chip/LIM-domain binding protein (LDB)-single-stranded DNA-binding protein (SSDP) (ChiLS) compl
76 1) transcription factor and the co-regulator single-stranded DNA-binding protein 3 (SSBP3) regulates
77 ethods, this amplification requires only the single-stranded DNA-binding protein gp32 from bacterioph
78 overcome by the DNA-binding activity of the single-stranded DNA-binding protein RPA, efficient DNA r
79 nal proteins, including the telomeric repeat single-stranded DNA-binding protein Teb1 and its heterot
82 107Q amino acid changes in the mitochondrial single-stranded DNA-binding protein, a crucial protein i
85 d of telomeric sequence-specific double- and single-stranded DNA-binding proteins, Taz1 and Pot1, res
86 ic target sites and report that simultaneous single-stranded DNA break formation at donor and accepto
87 measure the kinetics of translocation along single-stranded DNA by the helicase Hel308 from Thermoco
88 aN substrates modified with thiolated ssDNA (single stranded DNA) can be successfully used in the ana
90 slocates sequentially hand-over-hand along a single-stranded DNA coil, akin to the way AAA+ ATPases (
91 oligonucleotide-based FISH probes with long, single-stranded DNA concatemers that aggregate a multitu
92 nt R-loops (RNA-DNA hybrids with a displaced single-stranded DNA) create DNA damage and lead to genom
93 J and RAP80 exposed to MMC are attributed to single-stranded DNA created by Mre11 and CtIP nucleases.
94 s, as well as numerous circular Rep-encoding single-stranded DNA (CRESS DNA) viral genomes, were iden
95 e, and Iflaviridae and circular Rep-encoding single-stranded DNA (CRESS-DNA) virus, were also detecte
98 ate immune response is the APOBEC3 family of single-stranded DNA cytosine deaminases, which inhibits
99 erfacial potential changes were measured for single-stranded DNA detection with an unprecedented zept
101 -CRISPR), a targeting strategy in which long single-stranded DNA donors are injected with pre-assembl
103 A double-strand breaks (DSBs) to generate 3'-single-stranded DNA facilitates DSB repair via error-fre
104 ki2-like nucleic acid helicase that provides single-stranded DNA for alkylation damage repair by the
105 E2Ct, fail to induce RPA phosphorylation and single-stranded DNA formation, leading to defects in PCN
106 The separation and partitioning of large single-stranded DNA fragments of the homologous chromoso
107 We demonstrated that Brca2 protein prevents single-stranded DNA gap accumulation at replication fork
108 nthesis downstream of the lesion, creating a single-stranded DNA gap that is repaired primarily in an
109 tions arise through the aberrant repair of a single-stranded DNA gap, in a process that is dependent
113 phosphate, and also for cytosine residues in single-stranded DNA generated from a phagemid, in which
115 vely charged DNA binding protein J guide the single-stranded DNA genome into the icosahedral capsid.
116 tructures of Pf4 with and without its linear single-stranded DNA genome, and studied Pf4 assembly int
117 are structurally simple viruses with linear single-stranded DNA genomes and nonenveloped icosahedral
118 geminiviruses (plant viruses with circular, single-stranded DNA genomes) are the major group of emer
120 determine how they contribute to duplex and single-stranded DNA handling, and test the cellular cons
121 vimetric analytical techniques, we find that single-stranded DNA has a significant flame-retardant ef
122 ded binding proteins both protect and expose single-stranded DNA has important implications for our u
123 an essential replisome component that binds single-stranded DNA, has a role in replication-coupled n
124 trol the translocation speed of helicases on single-stranded DNA, however the cause of these effects
125 They exhibit 5' exonuclease activity on single-stranded DNA, hydrolyzing it at the acidic pH ass
126 which long distance binding (25 angstrom) of single-stranded DNA in an allosteric site primes the act
128 unequivocally establishes the existence of a single-stranded DNA incorporation pathway in human cells
130 nded sites and also at AT-rich regions where single-stranded DNA is exposed during origin opening.
131 sversion substitutions; results suggest that single-stranded DNA is formed during the genesis of the
132 ude that ROS contribute to TLD by converting single-stranded DNA lesions into double-stranded DNA bre
133 o three hexanucleotide repeats resulted in a single-stranded DNA-like mechanical behavior under all c
134 NA hybridized to the complementary DNA and a single-stranded DNA loop, are formed in switch regions o
135 molecular Fe(II)(4)L(4) tetrahedron binds to single stranded DNA, mismatched DNA base pairs, and thre
137 pose that these contigs correspond to linear single-stranded DNA molecules that fold onto themselves
138 olecule arrays by electrostatically adhering single-stranded DNA of gene-like length onto positively
140 ce receptor of interest is conjugated with a single-stranded DNA oligonucleotide, which hybridizes to
143 ins for Proteomics) is an approach that uses single-stranded DNA oligonucleotides to capture specific
144 and diffusion constants of several different single-stranded DNA oligonucleotides trapped in an MspA
148 In this regard, aptamers, as artificial single-stranded DNA or RNA oligonucleotides with catalyt
150 nvolves introducing multiple, short pairs of single-stranded DNA overhangs to components of the struc
151 sequence, the proteinosome payload (dextran, single-stranded DNA, platinum nanoparticles) is traffick
153 which is able to detect the hybridization of single stranded DNA probe with its complementary target
154 fficient covalent immobilization of purified single-stranded DNA probe oligomers on cleaned gold micr
156 nthesized oligonucleotides or amplicon-based single-stranded DNA probes and validated the technique o
157 relies on the immobilization on a surface of single-stranded DNA probes that bind complementary targe
158 or annealing activities limit the amount of single-stranded DNA product that Pif1 can generate, lead
159 nd that the Cas4-Cas1-Cas2 complex processes single-stranded DNA provided in cis or in trans with a d
161 ine starvation leads to accumulation of both single-stranded DNA regions and intracellular ROS, and i
162 ivery of CRISPR/Cpf1 ribonucleoproteins with single-stranded DNA repair templates results in precise
163 stranded MLPA products and subsequently to a single stranded DNA reporter probe bearing a HRP molecul
164 d complex thereafter nonspecifically cleaves single-stranded DNA reporter probes labeled with a fluor
165 nd resection, which generates long tracts of single-stranded DNA required for checkpoint activation a
166 ng of layered rGO and rGO/gold nanoparticles/single stranded DNA (rGO/AuNPs/ssDNA) composites over PE
169 lthough a UvrD monomer can translocate along single-stranded DNA, self-assembly or interaction with a
172 eavage can be rapidly digested by a 3' to 5' single-stranded DNA-specific exonuclease, indicating Cas
173 de experimental evidence that ComFA binds to single stranded DNA (ssDNA) and has ssDNA-dependent ATPa
175 ine nucleotides, generating deoxyuridine, in single stranded DNA (ssDNA) intermediates produced durin
176 ipment and facilitates the immobilization of single stranded DNA (ssDNA) probe sequences on a wide va
177 becomes activated and degrades a fluorescent single stranded DNA (ssDNA) reporter present in the assa
178 hanistic understanding of Sgs1 activities on single stranded DNA (ssDNA), which is a central intermed
180 eation rate of ScDmc1 results from its lower single-stranded DNA (ssDNA) affinity, compared to that o
182 ich forms helical nucleoprotein filaments on single-stranded DNA (ssDNA) and catalyzes strand invasio
183 ate-free synthesis of high-molecular-weight, single-stranded DNA (ssDNA) and demonstrate that it proc
184 by hyperphosphorylation of RPA, a sensor of single-stranded DNA (ssDNA) and DNA replication stress.
186 nnealase, a protein that binds complementary single-stranded DNA (ssDNA) and facilitates its annealin
187 A orchestrates these processes by binding to single-stranded DNA (ssDNA) and interacting with several
189 he AID/APOBEC enzymes deaminate cytosines in single-stranded DNA (ssDNA) and play key roles in innate
191 replication by excising oxidized bases from single-stranded DNA (ssDNA) and unhooking interstrand cr
192 ere, three different methods that can detect single-stranded DNA (ssDNA) are utilized to identify the
194 loading of Redbeta directly onto the initial single-stranded DNA (ssDNA) at a 3'-overhang, and second
195 The XPA protein functions together with the single-stranded DNA (ssDNA) binding protein RPA as the c
198 d-specific excision that begins at a distant single-stranded DNA (ssDNA) break and proceeds back past
199 ing that Exo1 can digest a randomly selected single-stranded DNA (ssDNA) but not a poly(dT) oligonucl
200 hemically, human RAD51 polymerises faster on single-stranded DNA (ssDNA) compared to double-stranded
204 atalytic polypeptide-like (APOBEC) family of single-stranded DNA (ssDNA) cytosine deaminases provides
205 iency virus type 1 (HIV-1) infectivity, is a single-stranded DNA (ssDNA) deoxycytidine deaminase with
206 luorescent sensor array made of aptamers and single-stranded DNA (ssDNA) dyes for multiplexed detecti
207 f a DSB, controlling the formation of the 3' single-stranded DNA (ssDNA) filament needed for recombin
209 through the cell cytoplasm, and deliver the single-stranded DNA (ssDNA) genome to the nucleus, where
211 dimeric protein that potentially binds with single-stranded DNA (ssDNA) in a manner similar to human
212 n is a highly dynamic process that generates single-stranded DNA (ssDNA) in the genome as 'transcript
214 induces the generation of large stretches of single-stranded DNA (ssDNA) intermediates that are rapid
215 mportant DNA metabolic events by stabilizing single-stranded DNA (ssDNA) intermediates, activating th
218 coupled with a gold substrate can resolve a single-stranded DNA (ssDNA) molecule with a spatial reso
221 epsilon has greater contact with the nascent single-stranded DNA (ssDNA) of the leading strand on act
222 nds of linear chromosomes and terminate in a single-stranded DNA (ssDNA) overhang recognized by POT1-
223 nerated DSB ends are processed to yield long single-stranded DNA (ssDNA) overhangs, which are quickly
225 In the marine environment, only a few lytic single-stranded DNA (ssDNA) phages have been isolated an
226 her hand, BLM and RECQ5 demonstrated similar single-stranded DNA (ssDNA) reeling activities that were
227 in models containing up to 1-kb inserts when single-stranded DNA (ssDNA) repair templates are supplie
229 ceeds via binding of RPA, RAD51, and DMC1 to single-stranded DNA (ssDNA) substrates created after for
230 often begins with creation of initiating 3' single-stranded DNA (ssDNA) tails on each side of a doub
233 te of cytosine deamination is much higher in single-stranded DNA (ssDNA) than in double-stranded DNA,
234 tly, we find no evidence for BLM activity on single-stranded DNA (ssDNA) that is bound by replication
235 and lagging strands leads to accumulation of single-stranded DNA (ssDNA) that promotes mutation.
236 egy relies on the preferential adsorption of single-stranded DNA (ssDNA) to GO over aptamer-target co
238 helicase activity, ScPif1 is also known as a single-stranded DNA (ssDNA) translocase, while how ScPif
240 tion and genomic substitution rates, RNA and single-stranded DNA (ssDNA) viruses may be important con
242 gle-stranded DNA binding protein (SSB) wraps single-stranded DNA (ssDNA) with high affinity to protec
243 (AFM) to show that Ver preferentially binds single-stranded DNA (ssDNA) with no sequence specificity
246 ate containing RNA:DNA hybrids and displaced single-stranded DNA (ssDNA), has emerged as a major sour
247 t of DNA-RNA hybridization and the displaced single-stranded DNA (ssDNA), have been identified in bac
248 ) for the label-free electrical detection of single-stranded DNA (ssDNA), in-solution- and on-chip-hy
249 on of the DNA damage signal, accumulation of single-stranded DNA (ssDNA), sensitivity to replication
250 ins engineered for large-scale production of single-stranded DNA (ssDNA), we probed the substrate spe
251 py structure of human CST bound to telomeric single-stranded DNA (ssDNA), which assembles as a decame
252 or the detections of metal ion, dopamine and single-stranded DNA (ssDNA), with detection limits of 1.
253 sitive coactivator of transcription (PC4), a single-stranded DNA (ssDNA)-binding protein, as a novel
257 is a bifunctional enzyme that contains both single-stranded DNA (ssDNA)-specific nuclease and motor
264 PF and ERCC-XPF and show that the binding to single-stranded DNA (ssDNA)/dsDNA junctions is dependent
265 SCNT decreased in order with the binding of single-stranded DNA (SSDNA, probe DNA) and double-strand
266 ch is able to detect hybridization of probe (single stranded DNA-ssDNA) and hybrid (double stranded D
268 ese mutants compared with wild type DnaC for single-stranded DNA, suggesting that the substitutions a
269 esection of broken ends to generate long, 3' single-stranded DNA tails, annealing of complementary se
271 ial signal was generated by hybridization of single stranded DNA targets to immobilized recognition p
272 gents, to prime second strand synthesis of a single-stranded DNA template and generate millions of pa
273 res formed by an RNA:DNA hybrid and unpaired single-stranded DNA that represent a source of genomic i
275 rial strategies (1) , especially small lytic single-stranded DNA (the microviruses) and RNA phages (t
278 OBEC3A, an enzyme that converts cytosines in single-stranded DNA to uracil, and mutations in a variet
279 D/APOBEC family enzymes convert cytosines in single-stranded DNA to uracils, causing base substitutio
281 In the case of the ubiquitous human circular single-stranded DNA virus family Anelloviridae, there is
282 s endocytose Pf, and internalization of this single-stranded DNA virus results in phage RNA productio
283 ) and Minute Virus of Mice (MVM), both T = 1 single stranded DNA viruses, and Bromo Mosaic Virus (BMV
286 19) uncover a previously undefined family of single-stranded DNA viruses, Redondoviridae, in human or
290 ore, the measurements of thermally denatured single-stranded DNA were carried out and the value of (G
292 uble-strand breaks creates long stretches of single-stranded DNA, which are rapidly bound by replicat
293 tides, called staple strands, to fold a long single-stranded DNA, which is called a scaffold strand,
294 an entry site for Exo1 in vitro to generate single-stranded DNA, which would be susceptible to both
295 eir destinations allows for a simple robot a single-stranded DNA with one leg and two foot domains fo
297 reaction (PER) cascades, which grow nascent single-stranded DNA with user-specified sequences follow
298 for deaminating cytosine bases to uracil in single-stranded DNA, with characteristic sequence prefer
299 Here, we present a study of surfactant and single-stranded DNA-wrapped SWNTs suspended in aqueous s
300 A Polymerase Cofactor), preferentially binds single-stranded DNA, yet contains a structural fold dist