ライフサイエンスコーパス: sizeable

1 e recipient through adoptive transfer, and a sizeable abscopal effect on distant, untreated lesions c

2 whereas other regions are more refractory to sizeable amino acid losses.

3 ranean diet in stroke prevention seemed more sizeable among males.

4 ption of mango (Mangifera indica) generate a sizeable amount of kernel waste with enormous and largel

5 lands in ten Midwestern US states to produce sizeable amounts of biomass and concurrently mitigate GH

6 een partially challenged by the isolation of sizeable amounts of protease-sensitive PrP(Sc) isoforms

7 ly, condensin typically reels in DNA in very sizeable amounts with ~200 bp on average per single extr

8 The macroeconomic burden of road injuries is sizeable and distributed unequally across countries and

9 l, the absolute number within a clone can be sizeable and is contained primarily within the CD38(+) f

10 AOMs that appear capable of safely achieving sizeable and sustained body weight loss.

11 ocalized observational data to constrain the sizeable and variable emissions from these arid, agricul

12 current and TTX-sensitive current were both sizeable at subthreshold voltages between spikes.

13 us is a two-dimensional semiconductor with a sizeable band gap.

14 electron mobility, ready electron transport, sizeable band gaps and ease of hybridisation, they are s

15 se reflectance spectroscopy, GaSI displays a sizeable bandgap of 3.69 eV, owing tostrong covalent int

16 semi-metallic graphene, layered TMDCs have a sizeable bandgap.

17 chalcogenides and buckled nanomaterials with sizeable bandgaps.

18 nflict areas' where road building could have sizeable benefits for agriculture but with serious envir

19 A sizeable body of evidence has recently emerged to sugges

20 Over the last decade, a sizeable body of literature has examined its effects on

21 el provides structural rationalization for a sizeable body of Taxol structure-activity relationship d

22 These findings suggest a sizeable burden of CHE in people seeking care for chroni

23 highest for PCV31, with PCV21 also targeting sizeable burdens of adult disease.

24 n of minimally invasive surgery may have had sizeable but overlooked effects on medical expenditures

25 ted with wealth beyond age 65 years remained sizeable but was much smaller than the smoking different

26 g function of temperature, and indicate that sizeable, but hitherto unobserved, TRAIL affinity differ

27 rior is a widespread mechanism to distribute sizeable cargos within prokaryotic cells.

28 ructures is a crucial prerequisite to obtain sizeable CD signals.

29 In addition to CD8alphabeta T cells, two sizeable CD8alpha(+)beta(-) non-T cell populations were

30 udy provides carbon isotope constraints on a sizeable, centennial-scale CO(2) jump at the onset of Ma

31 st-principles calculations which indicates a sizeable charge transfer of electrons (0.4-0.6 e) from 1

32 ents with subthreshold amblyopia represent a sizeable cohort in real-world amblyopia practice.

33 er combined voluntary exercise training in a sizeable cohort of female mice (n = 7-10 per group and a

34 future treatments that can lower IOP in the sizeable cohort of hypertensive glaucoma patients that r

35 Importantly, a sizeable cohort of species are self-sterile despite the

36 MRI-derived radiomic features derived from a sizeable cohort.

37 at the OmpR is responsible for controlling a sizeable component of the transcriptional programme to a

38 We obtained a sizeable conflict adaptation effect (measured as the mod

39 ac repolarization and polygenic risk, with a sizeable contribution from polygenic risk.

40 in periolivary nuclei ipsilaterally, with a sizeable contribution from the contralateral ventral nuc

41 nal bone mineral status sufficient to make a sizeable contribution to maternal and fetal calcium econ

42 Romanian Eneolithic sample with a minor, but sizeable, contribution from Anatolian farmers, suggestin

43 Significant and sizeable correlations were obtained in 12 of 15 behavior

44 The sizeable costs of a COVID-19 response in the health sect

45 est that the dinosaurian defecators consumed sizeable crustaceans that sheltered in rotting logs.

46 pressed as a viral minigene product formed a sizeable cytosolic pool continuously presented for hours

47 as been a significant effort to employ these sizeable data in the investigation of rare disease.

48 s needed on pancreatic cancer, which shows a sizeable decline for young men only.

49 dults, a low-dose cocaine challenge evokes a sizeable decrease in myocardial perfusion.

50 A sizeable decrement in FGU in response to glucose feeding

51 oward more expanded states for cases where a sizeable difference in solvent-accessible surface area e

52 r VF sensitivities, it is unlikely to make a sizeable difference to improving the time to detect VF p

53 poor prognosis with high mortality but with sizeable differences depending on additional baseline an

54 The effect is similar across sites, despite sizeable differences in culture and ethnic composition.

55 ome of these proteins form dense droplets of sizeable dimensions already below the critical concentra

56 unique region flanked at each terminus by a sizeable direct repeat.

57 s disease, suggesting that it might confer a sizeable disease risk when present on only one allele.

58 iment to another, and that there may also be sizeable disparities between batches within an experimen

59 ented cases of acute MI (group A) revealed a sizeable distribution of apoptotic cells visible on gros

60 A sizeable distribution of apoptotic cells, similar to tha

61 t lineage of STEC O157:H7 in England, with a sizeable domestic reservoir.

62 We also measured a sizeable doping-induced mass renormalization driven by t

63 oundings, may be highly vulnerable to future sizeable earthquakes when accumulated elastic strain ene

64 Considering that sizeable effects have been already observed at routinely

65 s occupancy and habitat use models, we found sizeable effects of coyote habitat use on that of red fo

66 There were sizeable effects of tumor-node-metastasis (TNM) stage an

67 Sizeable electronic coupling in A and B opens, on one ha

68 Although the acute disease burden is sizeable, emerging data suggest norovirus may be associa

69 terstrand hydrogen bonding sites, along with sizeable energy changes, indicating the potentially seri

70 troscopy can track these states by measuring sizeable energy gaps and Floquet band formation on femto

71 This measurement bias is sizeable enough to be relevant for researchers and clini

72 The effect is sizeable even at low surface ligand density.

73 titis C (CHC) infection is associated with a sizeable excess mortality risk.

74 (quantum yield ~1%) drives requirements for sizeable excitation doses (~1-10 kW/cm(2)) that are sign

75 state in the upper atmosphere, allowing for sizeable expansion and escape of neutral hydrogen gas.

76 Based on the sizeable experience of past decades, the key features of

77 nd, predominantly due to non-availability of sizeable families.

78 or geodetic observations while producing the sizeable far-field tsunami.

79 A sizeable, feedforward, GABAergic projection exists from

80 its control is sufficiently high to achieve sizeable flux increases over less than 20% of the space.

81 The effect was sizeable for the aspect ratio task but substantially sma

82 tely reveal a set of genes responsible for a sizeable fraction of AMD.

83 ssion but has restricted gene evolution in a sizeable fraction of barley's genes.

84 A sizeable fraction of both sequence motifs and TF-gene in

85 he APC, KRAS, and p53 genes-are mutated in a sizeable fraction of CRCs, and a larger collection of ge

86 ification procedure, by which we find that a sizeable fraction of Doa4 copurifies with the protease.

87 imate that all possible single mutants and a sizeable fraction of double mutants are generated during

88 A sizeable fraction of eukaryotic proteins contain intrins

89 hod to make accurate predictions despite the sizeable fraction of false positives that are known to e

90 On the other hand, a sizeable fraction of in-frame indels at the BRCT domain

91 LN) and upregulate MHC-II, as evidenced by a sizeable fraction of mouse DNT cells in Peyer's patches

92 A sizeable fraction of multiple myeloma (MM) is expected t

93 lation stroke, and to show that it affects a sizeable fraction of patients and has the predicted nega

94 proximately 1 year, this approach excludes a sizeable fraction of patients dying before such a landma

95 itis C virus (HCV) infection fails to cure a sizeable fraction of patients treated.

96 ease-resistant MBP TCR Tg mice also harbor a sizeable fraction of peripheral CD4(+) T cells lacking s

97 peptides bound to self-MHC molecules, but a sizeable fraction of peripheral T cells can also respond

98 Also, achenes were found to contribute a sizeable fraction of phenolic acids and hydrolysable tan

99 emonstrate in the hippocampus in vivo that a sizeable fraction of postnatal NG2+ progenitor cells are

100 Nevertheless, a sizeable fraction of proteins remain difficult targets d

101 Remarkably, a sizeable fraction of resting T cells was stably transduc

102 This ARMC5 checkpoint normally curtails a sizeable fraction of RNAPII transcription, and ARMC5 kno

103 After reinfection, a sizeable fraction of secondary memory T cells in the cir

104 and stable in somatic cells, representing a sizeable fraction of silent genes.

105 ial became sufficiently negative to remove a sizeable fraction of the inactivation (half inactivation

106 at the outburst was prematurely ended when a sizeable fraction of the outer disk was depleted by the

107 through distinct gene pools, thus scanning a sizeable fraction of the overall repertoire of promiscuo

108 , we describe Robo3 mouse mutants in which a sizeable fraction of the trigemino-thalamic inputs proje

109 the eddy heat and salt transports both are a sizeable fraction of their respective total transports.

110 multiple signs of elevated TCR signaling, a sizeable fraction of them escaped deletion to selectivel

111 ained and functionally competent; however, a sizeable fraction of these memory T cells are short-live

112 A sizeable fraction of these variants are predicted to be

113 in the 1- to 29-year age group meant that a sizeable fraction of women of reproductive age received

114 epresenting union and intersection between a sizeable fractions of individual networks, respectively.

115 These SNPs explained sizeable fractions of metabolite heritabilities when con

116 rs, and are not separated from each other by sizeable free energy barriers.

117 taceous placental mammal and reinforcing the sizeable gap between molecular and fossil divergence tim

118 ganisms in the Opisthokonta clade, leaving a sizeable gap in our understanding of flagella evolution

119 The sizeable genetic distance between DRC60 and ZR59 directl

120 as designed to perform batch annotation on a sizeable genomic region.

121 Despite the sizeable global burden of hearing loss, cochlear implant

122 cell disease, a genetic disorder affecting a sizeable global demographic, manifests in sickle red blo

123 In summary, a sizeable group of clinically diagnosed ADD and aMCI pati

124 We find that sizeable H2-M3-restricted T cell responses, occurring ea

125 areer or community often are associated with sizeable health benefits.

126 Heart failure carries a sizeable health burden.

127 Ongoing tobacco tax increases deliver sizeable health gains and health sector cost savings and

128 ), and Marburg virus (MARV) have also caused sizeable human outbreaks.

129 own syntaxin family proteins in possessing a sizeable hydrophilic domain of 63 amino acids that is C-

130 ted towards first-time mothers, would have a sizeable impact upon maternal and infant health in almos

131 TKA is associated with sizeable improvements in 3 levels of physical functionin

132 49]) and creativity (0.22, [-0.14, 0.58]) to sizeable improvements in rigour of methodology (0.99, [0

133 lage and those in the control group, despite sizeable improvements in walkability and neighbourhood p

134 ignalling pathways is probably necessary for sizeable improvements to reverse the progression of thes

135 s from MCs, A 61603 (30 nm-1 muM) produced a sizeable increase in the frequency of spontaneous and mi

136 nd behavioural risk factors, juxtaposed with sizeable increases in DALYs attributable to metabolic ri

137 ted in lower total ADHD medication spending, sizeable increases in out-of-pocket expenditures for fam

138 There were sizeable individual differences in cone packing density

139 important to note, however, that there were sizeable individual differences-the judgments of half of

140 These results demonstrate a sizeable inefficiency in abdominal organ allocation asso

141 e-living organisms on Earth, and they have a sizeable influence across ecosystems.

142 ization of 1.5 +/- 0.2 kcal/mol, revealing a sizeable influence of lipid composition on TM complex st

143 Firstly it contains two sizeable insertions compared to the non-cardiac isoforms

144 -state quasi-particles with a light mass and sizeable interactions.

145 Sizeable inverse associations with stroke and respirator

146 d purchase mRNA covid-19 vaccines, including sizeable investments in the three decades before the pan

147 tion in Purkinje neurons is accompanied by a sizeable ionic current.

148 T cells (Tregs) for treating autoimmunity, a sizeable knowledge gap exists regarding Treg fate in hum

149 A sizeable lag in selecting feature information is seen wh

150 resents a previously unidentified and likely sizeable link in both the marine carbon and sulfur cycle

151 ogenesis, however, remain obscure, despite a sizeable literature exploring the links between alterati

152 We summarized the sizeable literature in resource-rich settings as well as

153 Indeed, a sizeable literature now links a wide range of stressors

154 ly two decades ago and has since generated a sizeable literature.

155 ed early after AMI can accurately identify a sizeable low-risk group who have a <2% death and reinfar

156 nized mice, resulting in the generation of a sizeable melanoma-specific naive CD8(+) T-cell populatio

157 y seems to be maintained by small numbers of sizeable micrometastases that escape from growth restric

158 would not consider an altruistic stranger, a sizeable minority (38%) would.

159 Second, however, a sizeable minority of exons show strong differences betwe

160 Previous studies have found that a sizeable minority of newly disabled older persons recove

161 t in late adolescence or early adult life, a sizeable minority of patients first become ill in middle

162 Intriguingly, a sizeable minority of patients under TNFi therapy develop

163 Even at specialty cancer centers, a sizeable minority of patients with rectal cancer treated

164 (PCWP) are correlated in heart failure, in a sizeable minority of patients, the RAP and PCWP are not

165 A sizeable minority of strokes occur in hospitalized patie

166 ever, surveys have consistently found that a sizeable minority of US residents do not plan to get a C

167 most participants, more than additive for a sizeable minority, and competitive in very few.

168 A sizeable minority, however, prefer decision-making deleg

169 is non-negligible essentially when there is sizeable mobility from a high prevalence country or coun

170 On the basis of this rationale, sizeable mono-chirality topological stripe is readily ac

171 This high burden of disease, which incurs sizeable morbidity, may be worsening with the proportion

172 bad prognosis of cholangiocarcinoma and the sizeable morbidity-mortality after LT, timely indication

173 e recombinant system is based also contained sizeable mutant subpopulations, whose presence was confi

174 with referent women provided evidence for a sizeable neuroprotective effect of estrogen before age 5

175 ward rapid and efficient resequencing of any sizeable, non-repeat portion of the human genome.

176 ly packed; there are no introns and only one sizeable noncoding, or control, region containing key ci

177 rinciple reveals all genetic variants, their sizeable number and poorer annotation make prioritizatio

178 Vasospasm occurs in a sizeable number of children with moderate and severe tra

179 Such a change is likely to affect a sizeable number of drug-dosing decisions.

180 n be molded by natural selection to create a sizeable number of novel phenotypes.

181 SARS-CoV-2 carries a sizeable number of proteins that are accessory to replic

182 A sizeable number of studies have implicated the default n

183 es as a more evolutionarily real unit, but a sizeable number still felt that genera were more evoluti

184 rial China when climate conditions sustained sizeable oases in the region.

185 sion, but some unfortunate exposures causing sizeable onward transmission.

186 ansmission response can be obtained within a sizeable optical isolation region of ~210 mW.

187 network via Donnan equilibrium and creates a sizeable osmotic pressure to enlarge the free volume and

188 ite varicella vaccination coverage of 80%, a sizeable outbreak occurred.

189 e results demonstrate that the presence of a sizeable parasite greatly reduces the ability of RBCs to

190 lping to accommodate parts of the epitope in sizeable paratope gullies.

191 such measures is hampered by the fact that a sizeable part of the population fails to see their need.

192 d inform long-term health management in this sizeable patient population.

193 ials have received increasing attention, and sizeable PBGs have been reported in quasi-crystalline st

194 Our results demonstrate the existence of sizeable PBGs in these disordered structures and provide

195 ging results, research also indicates that a sizeable percentage of couples fail to achieve significa

196 Notably, a sizeable percentage of elderly HF patients have cardiac

197 stal adenoma would result in not detecting a sizeable percentage of the prevalent advanced proximal a

198 er, Clades VII and subcluster "5.3" formed a sizeable percentage of the Synechococcus community in Ma

199 (61% LKD programs and 73% LLD programs), and sizeable percentages (31% LKD and 37% LLD) endorsed 5 ye

200 We achieve a sizeable performance boost compared to our previously pu

201 ability of a minimally invasive approach for sizeable pheochromocytomas.

202 apy in patients with acute heart failure and sizeable pleural effusion.

203 minute subset of their binding sites from a sizeable pool of putative sites in large mammalian genom

204 f sequenced genomes has expanded the already sizeable population of cysteine peptidases from parasite

205 f infiltrating CD4(+) and CD8(+) cells and a sizeable population of immunoglobulin A (IgA)- and IgG-s

206 embles into predominantly T=4 capsids with a sizeable population of larger, nonicosahedral structures

207 of the C2B domain contacts the membrane in a sizeable population of molecules of both membrane-bound

208 pacemaker activity is a latent property of a sizeable population of SDH cells during early life.

209 table in mouse and not detected in humans, a sizeable population of uILC3s is found in human endometr

210 In most connective tissues, sizeable populations of fetal-derived mast cells persist

211 In two sizeable populations with CKD, a proteomic risk model fo

212 microbes beneath the MOR may be consuming a sizeable portion (at least ~30%) of all produced H(2), s

213 nefficient at the TCRalpha locus, allowing a sizeable portion of T cells to carry two functional TCRs

214 We found that a sizeable portion of Th17 cells express HIV coreceptor CC

215 ically understudied populations that carry a sizeable portion of the heart failure burden.

216 ggesting that it affects sleep behavior in a sizeable portion of the human population.

217 Dissolved organic matter (DOM) comprises a sizeable portion of the redox-active constituents in the

218 Modest sets of SNPs (n = 1-23) explained sizeable portions of genetic effects for many metabolite

219 Massive simulations over sizeable portions of the cortex with feature resolution

220 A sizeable posterior occipital cortical area (BA 17/18) ex

221 ency enhancement in NA activity assays but a sizeable potency increase in a 4-day cytopathic effect a

222 retrospective birth location data, showing a sizeable probability of misreporting, with 28% of birth

223 oves the management and quality of life of a sizeable proportion of aHUS patients while reducing the

224 (CHIP) is a preclinical condition wherein a sizeable proportion of an individual's circulating blood

225 uble immunogold labeling demonstrated that a sizeable proportion of bone sialoprotein particles were

226 Gene mutations are responsible for a sizeable proportion of cases of heart failure.

227 However, a sizeable proportion of food products bear no label, and

228 ovel competing risk analysis suggests that a sizeable proportion of HF risk may not be associated wit

229 The current analysis using UAD2 identified a sizeable proportion of hospitalized adult CAP associated

230 the identification of 166 genes for which a sizeable proportion of humans are homozygous for predict

231 itude of the school-aged child population, a sizeable proportion of influenza virus transmission even

232 A sizeable proportion of late-stage PDACs were detected du

233 cognition that dynamic effects account for a sizeable proportion of mass-balance changes observed in

234 In this study, we show that a sizeable proportion of mature CD4(+)CD8(-) (CD4SP) thymo

235 A sizeable proportion of medically controlled glaucoma pat

236 anic/Latino adults of diverse backgrounds, a sizeable proportion of men and women had adverse major r

237 s less definitive in patients with NASH as a sizeable proportion of NASH patients with HCC do not hav

238 mmon while optic disc edema is present, with sizeable proportion of patients experiencing dramatic vi

239 , costs and unresponsiveness to therapy in a sizeable proportion of patients limit their use, making

240 However, a sizeable proportion of patients presents with an impaire

241 A sizeable proportion of patients with advanced cancer con

242 In conclusion, in a sizeable proportion of patients with advanced HCV, LADR

243 o 90% of patients with polycythemia and in a sizeable proportion of patients with other myeloprolifer

244 Yet, in a sizeable proportion of patients, primary percutaneous co

245 ity and clinical trials settings; however, a sizeable proportion of subjects had conflicting biomarke

246 A sizeable proportion of SUDEP cases have clinically relev

247 l and neonatal factors appeared to mediate a sizeable proportion of the aforementioned association be

248 d with age, telomere length (TL) explained a sizeable proportion of the variance in volume of the hip

249 th exhibit significant strengths; however, a sizeable proportion of these families appear to be strug

250 revealed that microglial cells constitute a sizeable proportion of ventricular zone cells during lat

251 of adolescents, young adults, and adults, a sizeable proportion reported having used nonnicotine e-c

252 nal groups have used this approach to create sizeable public cell line repositories available to the

253 ause of gastroenteritis worldwide and thus a sizeable public health burden.

254 This appears to originate from sizeable quantum corrections to the magnetoresistance.

255 e weak intermolecular hydrogen bonds and the sizeable quantum motion of the light hydrogen ions (prot

256 absorption wavelength from 330 to 394 nm, a sizeable red shift in the maximum emission wavelength fr

257 i in the electron transport chain can induce sizeable redox shifts in the oxidative or reductive dire

258 ally, we show that our approach results in a sizeable reduction in bias when estimating both absolute

259 A sizeable reduction in FGU occurs in just 24 h of IMM, wh

260 Mexico achieved sizeable reductions in burden due to several causes, suc

261 In addition, phytochrome loss leads to sizeable reductions in overall growth, dry weight, total

262 een reported in an alphaherpesvirus), (iv) a sizeable region of the genome is not required for viral

263 veys, we find that the human genome contains sizeable regions (stretching over tens of thousands of b

264 rred in bursts and propagated rapidly across sizeable regions of the LM layer and were blocked by hep

265 This is largely due to a sizeable reservoir of latently infected individuals, who

266 that fibrin monomers must be able to undergo sizeable, reversible structural changes and that deforma

267 The sizeable right-asymmetry increase reported here may be a

268 3-dimensional biofilm architecture displays sizeable S. mutans microcolonies surrounded by fungal ce

269 al advances, but negative trials also have a sizeable scientific impact by generating important scien

270 network, including gossip, which comprises a sizeable share of daily conversation.

271 ICUs are used in a sizeable share of hospitalizations.

272 , and economic marginalization account for a sizeable share of the EJ gap.

273 The sizeable shift in transition temperature scales with cur

274 ealth Workforce Simulation Model forecasts a sizeable shortage of ophthalmology supply relative to de

275 trial carbon sink without accounting for the sizeable sink due to forest demography.

276 Many languages have sizeable smell lexicons - smell is even grammaticalized.

277 Here we report sizeable spin-orbit torques in IrMn/CoFeB/MgO structures

278 Together with sizeable spin-orbit torques, these features make antifer

279 ew chiral perovskites reported here couple a sizeable spin-splitting with chiral degrees of freedom a

280 imensional icosahedral quasicrystals exhibit sizeable stop gaps and, despite their quasiperiodicity,

281 Overall, this protein group is a more sizeable, structure-based, histidine-ligated heme-depend

282 By contrast, a sizeable subgroup developed lasting clinical levels of a

283 engage and sustain viral suppression among a sizeable subgroup of people living with HIV who initiate

284 Because migraine worsens in a sizeable subgroup of sufferers, but not in most, identif

285 Nevertheless, a sizeable subset (about 1/3) having relatively realistic

286 risk profiling are essential to identify the sizeable subset at increased risk of sudden cardiac deat

287 Thus, MK defines a sizeable subset of patients with unfavorable cytogenetic

288 however, vulnerabilities and risks may be so sizeable that they require transformational rather than

289 dition, CD4-Cre x dnmt1(fl/fl) mice harbored sizeable thymic and peripheral populations of CD8(+)Foxp

290 e intermediate are very stable and introduce sizeable topological or energetic frustration that needs

291 Most often, a sizeable tumor cell subpopulation survives and remains q

292 oven difficult, in large part because of the sizeable uncertainty inherent in estimating or measuring

293 The sizeable unique environmental influence on beverage pref

294 This flexibility resulted in sizeable variation in the results of hypothesis tests, e

295 sults confirm that 20S proteasomes produce a sizeable variety of cis-spliced peptides, whereas trans-

296 oups with the highest extinction risk of any sizeable vertebrate group.

297 In fully adjusted models, there was still a sizeable wealth disparity in mortality after age 65 year

298 g a national survey experiment, we find that sizeable White presence at racial justice protests incre

299 In addition, the extent of mutation can be sizeable with approximately 32% of the IgM+ cases and ap

300 Thus, early in gestation, a sizeable yet underdeveloped organism requires circulatin