ライフサイエンスコーパス: skin substitute

1 the response to injury of a human bilayered skin substitute.

2 was observed with meshing of human bilayered skin substitute.

3 nfluence the subsequent functionality of the skin substitute.

4 required for hair development in engineered skin substitutes.

5 ts a massive influence on gene expression in skin substitutes.

6 eneic human cadaver skin grafts or synthetic skin substitutes.

7 an keratinocytes and fibroblasts in cultured skin substitutes.

8 ring healing of wounds treated with cultured skin substitutes.

9 rated adipose-derived mesenchymal cells into skin substitutes and found that adipose-derived mesenchy

10 nges in cultured melanocytes, modified human skin substitutes, and ex vivo skin.

11 No artificial skin substitutes are functionally equivalent to autologo

12 ry support, the early excision of burns, and skin substitutes are improving survival from massive bur

13 Skin substitutes are increasingly being used in the trea

14 The costs to Medicare for skin substitutes are inflated by reimbursement models th

15 We conclude that human bilayered skin substitute, as a prototypic bilayered skin substitu

16 were similar to the insulin-treated cultured skin substitutes at day 14, but by day 28 had deteriorat

17 lues similar to the insulin-treated cultured skin substitutes at day 14, but were significantly lower

18 s a promising alternative method to generate skin substitutes because it can replicate the structural

19 Bioengineered skin substitutes can facilitate wound closure in severel

20 ut because they contain only two cell types, skin substitutes cannot replace all of the functions of

21 s or Langerhans cells present in StrataGraft skin substitute compared to cadaver allograft, the stand

22 howed that the epidermal and dermal cultured skin substitute components express insulin-like growth f

23 Cultured skin substitutes consisting of collagen-glycosaminoglyca

24 Comparison of cultured skin substitutes (CSS) and split-thickness skin autograf

25 Cultured skin substitutes (CSS) consisting of autologous fibrobla

26 pacitance (SEC) of the epidermis in cultured skin substitutes (CSS) in vitro and after grafting to at

27 Cultured skin substitutes (CSS), prepared using keratinocytes, fi

28 Importantly, exposure to StrataGraft skin substitute did not induce the proliferation of pati

29 ised concerns about the costs to Medicare of skin substitutes, documenting pervasive fraudulent billi

30 igmented and prevascularized dermo-epidermal skin substitute (EarSkin) tested in immunocompromised ra

31 like growth factor I exhibited poor cultured skin substitute epidermal morphology throughout the expe

32 enitors can be utilized to vascularize human skin substitutes even in the setting of compromised host

33 Currently available skin grafts and skin substitutes for healing following third-degree burn

34 In this study, neonatal murine-only skin substitutes formed external hairs and sebaceous gla

35 irs without sebaceous glands, and human-only skin substitutes formed no follicles or glands.

36 xternal hairs and sebaceous glands, chimeric skin substitutes formed pigmented hairs without sebaceou

37 For example, in vivo-healed skin substitutes gained the expression of many native sk

38 d epidermal compartments, chimeric composite skin substitutes generated using up to 90% GFP-labeled N

39 Subsequently, cultured skin substitute grafts consisting of cultured human kera

40 y agreed with MTT data showing that cultured skin substitutes grown with insulin media had multiple l

41 Generation of skin appendages in engineered skin substitutes has been limited by lack of trichogenic

42 Cultured skin substitutes have become useful as adjunctive treatm

43 ts for excised, full-thickness burns, but no skin substitutes have the anatomy and physiology of nati

44 In contrast, the cultured skin substitutes in 50 ng per ml insulin-like growth fac

45 results suggest that incubation of cultured skin substitutes in medium containing vitamin C extends

46 The data show that incubation of cultured skin substitutes in medium containing vitamin C results

47 in human skin cultured ex vivo and in human skin substitutes in vitro were substantially diminished

48 Cultured skin substitutes incubated in 50 ng per ml insulin-like

49 owed significantly higher values in cultured skin substitutes incubated with insulin at incubation da

50 Cultured skin substitute inserts were evaluated at 2 and 5 wk for

51 by keratinocytes and fibroblasts in cultured skin substitutes is not sufficient to fully replace the

52 d skin substitute, as a prototypic bilayered skin substitute, is a truly dynamic living tissue, capab

53 Clinical efficacy of cultured skin substitutes may be increased if their carbohydrate

54 at 0.0, 0.01, 0.1, and 1.0 mM in a cultured skin substitute model on filter inserts.

55 Cultured skin substitutes (n = 3 per group) were evaluated in vit

56 Chimeric autologous/allogeneic bioengineered skin substitutes offer an innovative regenerative medici

57 ts greater physiologic stability in cultured skin substitutes over time, and that expression of insul

58 Furthermore, chimeric human skin substitutes stably engrafted in an in vivo mouse mo

59 e use of human DP cells in tissue-engineered skin substitutes (TESS).

60 Improved anatomy and physiology of cultured skin substitutes that result from nutritional factors in

61 would produce a fully stratified engineered skin substitute tissue and serve to deliver autologous k

62 for the formation of bioengineered chimeric skin substitute tissues, providing immediate formal woun

63 red keratinocytes, cultured fibroblasts, and skin substitutes using Affymetrix gene chip microarrays.

64 higher for 5 microg per ml insulin cultured skin substitutes versus all other treatment groups.

65 y 12 h, however, the wounded human bilayered skin substitute was healed by day 3, and a stratum corne

66 Cultured skin substitutes were grafted on full-thickness wounds i

67 Cultured skin substitutes were grafted to full-thickness wounds i

68 Cultured skin substitutes were prepared and incubated at the air-

69 Vascularized skin substitutes were prepared by seeding Bcl-2-transduc

70 limitation of hair regeneration, engineered skin substitutes were prepared with chimeric populations

71 These skin substitutes were transplanted onto C.B-17 SCID/beig

72 We seeded tissue engineered human skin substitutes with endothelial cells (EC) differentia

73 After grafting, cultured skin substitutes with vitamin C developed functional epi