ライフサイエンスコーパス: sleep deprivation

1 fy participants' vulnerability to subsequent sleep deprivation.

2 olfactory mechanisms alter food intake after sleep deprivation.

3 cally induced neuronal activity and physical sleep deprivation.

4 eir number of PVT lapses during one night of sleep deprivation.

5 behavioral adjustment to a novel task after sleep deprivation.

6 arousal in flies counteracts the effects of sleep deprivation.

7 s a reward processing hub sensitive to acute sleep deprivation.

8 in phagocytosis, are upregulated after acute sleep deprivation.

9 cting visual attention defects brought on by sleep deprivation.

10 g, whereas this was not observed after acute sleep deprivation.

11 ssions, including a session after full-night sleep deprivation.

12 izing and loss of dendritic spines following sleep deprivation.

13 m potentiation (LTP) due to saturation after sleep deprivation.

14 naptic plasticity phenotypes associated with sleep deprivation.

15 o reaction to increased sleep need following sleep deprivation.

16 aling and cognitive deficits associated with sleep deprivation.

17 account for the increase in SWA that follows sleep deprivation.

18 evoked potential and memory formation) after sleep deprivation.

19 TP-like plasticity in humans after sleep and sleep deprivation.

20 trocytes impairs the homeostatic response to sleep deprivation.

21 nitive susceptibility to, and recovery from, sleep deprivation.

22 nd impairments in long-term memory caused by sleep deprivation.

23 ignore neutral distracting information after sleep deprivation.

24 during sleep, wake, and after short or long sleep deprivation.

25 s the elevated Abeta accumulation induced by sleep deprivation.

26 inhibition and antisaccades-that occur after sleep deprivation.

27 heir active period and in response to forced sleep deprivation.

28 bserved with respect to both time of day and sleep deprivation.

29 ants and also in wild type animals following sleep deprivation.

30 IP cannot recover sleep after the night-time sleep deprivation.

31 restriction, and following subsequent acute sleep deprivation.

32 pus-dependent learning tasks associated with sleep deprivation.

33 e for the memory impairments associated with sleep deprivation.

34 r their membrane excitability in response to sleep deprivation.

35 elevated arousal threshold and resistance to sleep deprivation.

36 s wake, chronic sleep restriction, and acute sleep deprivation.

37 istal segments on apical dendrites following sleep deprivation.

38 activity, and food, during a period of total sleep deprivation.

39 Both involve short-term sleep deprivation.

40 ferent from those observed after acute total sleep deprivation.

41 gnificantly reduced after total sleep or REM sleep deprivation.

42 mmunity, during hospital bedrest, and during sleep deprivation.

43 r homeostatic regulation of sleep need after sleep deprivation.

44 contagion, but not mimicry, was affected by sleep deprivation.

45 to emotional faces or sensitivity to partial sleep deprivation.

46 to spend more money on food items only after sleep deprivation.

47 sleep depth, and the homeostatic response to sleep deprivation.

48 ypothalamic coupling after a single night of sleep deprivation.

49 individual differences in performance during sleep deprivation.

50 ypothalamic coupling after a single night of sleep deprivation.

51 ith increased sleep pressure following a 4-h sleep deprivation.

52 relative attentional vulnerability to total sleep deprivation.

53 relative attentional vulnerability to total sleep deprivation.

54 s to pay increased for food items only after sleep deprivation.

55 estricted sleep (n = 13) or 1 night of total sleep deprivation (24 hours of wakefulness) (n = 13).

56 During sleep deprivation, 27 metabolites (tryptophan, serotonin

57 Participants underwent partial sleep deprivation (3 h sleep opportunity at the end of n

58 Furthermore, the response to acute sleep deprivation (6 h) was significantly attenuated in

59 had a reduced homeostatic sleep response to sleep deprivation, a response modulated by the adenosine

60 human cerebrospinal fluid (CSF) and chronic sleep deprivation accelerates the spread of tau protein

61 This study investigated how a night of sleep deprivation affected performance during multiple t

62 We asked if sleep deprivation affects advice taking.

63 motion processing, but it is unclear whether sleep deprivation affects emotional mimicry and contagio

64 Sleep deprivation affects phosphorylation of regulatory

65 Several studies suggest that sleep deprivation affects risky decision making.

66 sleep and disturbances in delta power after sleep deprivation, all without observable changes in anx

67 Total sleep or REM sleep deprivation also prevented MD- and FC-induced redu

68 EG and fMRI tasks, we were able to show that sleep deprivation alters emotional reactivity by trigger

69 ice electrophysiology, we measured how acute sleep deprivation alters transmission at BLAp-NAc synaps

70 Here, we demonstrate that acute sleep deprivation amplifies pain reactivity within human

71 /or sleep duration or performed experimental sleep deprivation and assessed inflammation by levels of

72 Both sleep deprivation and caffeine treatment potentiated lig

73 Both sleep deprivation and caffeine treatment potentiated lig

74 Contrary to nocturnal rodents, both sleep deprivation and caffeine-induced arousal potentiat

75 The effects of sleep deprivation and certain medications can also affec

76 irst of metabolic profiling during sleep and sleep deprivation and characterization of 24 h rhythms u

77 ffect"), which has been partly attributed to sleep deprivation and circadian misalignment [1-6].

78 during the day and its deterioration during sleep deprivation and circadian misalignment.

79 nvestigations have focused on the effects of sleep deprivation and circadian time, little is known ab

80 nipulation of glymphatic activity, including sleep deprivation and cisternotomy, suppressed or elimin

81 y explain the antidepressive effect of acute sleep deprivation and deserve further study.

82 Sleep deprivation and disorders are linked to reduced DM

83 th peanut allergy and examined the effect of sleep deprivation and exercise.

84 adjusts cortical clock-gene expression after sleep deprivation and expedites REM-sleep recovery.

85 Here, we provide direct evidence linking sleep deprivation and false confessions.

86 Sleep deprivation and fatigue are common subjective comp

87 lity in 15 healthy male adults after 52 h of sleep deprivation and following 14 h of recovery sleep.

88 Here, we tested the association between sleep deprivation and food cue processing in a repeated-

89 we rigorously tested the association between sleep deprivation and food cue processing using high-res

90 ep-promoting MB microcircuit is increased by sleep deprivation and is necessary for homeostatic rebou

91 nue is the study of chrono-medical timing of sleep deprivation and light exposure for their positive

92 Additionally, the association between sleep deprivation and metabolic disorders such as diabet

93 ed to irregular sleep schedules resulting in sleep deprivation and misalignment of circadian rhythms,

94 ribute to the brain's coping mechanisms with sleep deprivation and point to a novel target to improve

95 Vigilant attention is impaired by sleep deprivation and restored after rest breaks and (mo

96 is upregulated already after a few hours of sleep deprivation and shows a further significant increa

97 ehavioral manifestations of sleep, wake, and sleep deprivation and specific measurable changes in the

98 f altered metabolic signaling in response to sleep deprivation and suggest that these signaling pathw

99 nscriptome data were collected under normal, sleep-deprivation and abnormal sleep-timing conditions t

100 econdary causes of weight gain (medications, sleep deprivation), and solicit patient motivation for w

101 M transitions, hindered recovery sleep after sleep deprivation, and impaired memory.

102 gnaling transmits changes in aggression upon sleep deprivation, and reduced aggression places sleep-d

103 well-established negative health outcomes of sleep deprivation, and the suggestion that availability

104 ermine brain mechanisms of action underlying sleep deprivations antidepressant effects, we examined i

105 ether the cognitive deficits associated with sleep deprivation are caused by attenuated cAMP signalin

106 sual or hearing impairment, dehydration, and sleep deprivation are effective for delirium prevention

107 ence or absence of sleep and the response to sleep deprivation are highly relevant when identifying b

108 processes restore learning ability following sleep deprivation are similarly unknown.

109 underlying altered pain processing following sleep deprivation are unknown.

110 he single neuron level, we find that chronic sleep deprivation, as well as Abeta expression, enhances

111 ed during non-rapid eye movement sleep after sleep deprivation at the network and single-cell level.

112 Moreover, sleep deprivation brings about vehicle accidents and med

113 ROS are not just correlates of sleep deprivation but drivers of death: their neutraliza

114 lects every-day sleep loss better than acute sleep deprivation, but its effects and particularly the

115 port non-specific triggers such as stress or sleep deprivation, but only rarely do seizures occur as

116 Moreover, sleep deprivation by gentle handling was reported to pro

117 Rationale: Sleep deprivation can alter endurance of skeletal muscle

118 ila melanogaster males, sleep pressure after sleep deprivation can be counteracted by raising their s

119 predictions of attentional performance when sleep deprivation cannot be avoided.

120 Partial sleep deprivation caused decreased activation in fusifor

121 sely fit group-average PVT data during acute sleep deprivation, chronic sleep restriction, and recove

122 sleep restriction and after 1 night of acute sleep deprivation compared to a regular sleep condition

123 ghrelin concentrations were increased after sleep deprivation compared with habitual sleep.

124 t metabolites significantly increased during sleep deprivation compared with sleep (taurine, formate,

125 Together, these findings establish that sleep deprivation compromises the faithful signaling of,

126 ial amplitude was significantly lower in the sleep-deprivation condition (4.5 muV [IQR, 2.5-6.4] vs.

127 In the sleep-deprivation condition, preinspiratory motor potent

128 , and homeostatic sleep-pressure response to sleep deprivation correlated negatively with the decreas

129 g/mL (95% CI [0.94, 49.6], P = .04), whereas sleep deprivation counteracted this decrease.

130 3 consecutive days, the second day being the sleep deprivation day.

131 In mice, we find that five hours of sleep deprivation decreases dendritic spine numbers sele

132 Five hours of total sleep deprivation directly following training impaired t

133 We demonstrate that sleep deprivation downregulates the expression of microR

134 Sleep deprivation during the night facilitates MIP secre

135 Exercise and sleep deprivation each significantly reduce the threshol

136 We show that sleep deprivation enhances pain responsivity within the

137 tered neural signature, we further show that sleep deprivation expands the temperature range for clas

138 esting state human EEG data during a 40-hour sleep deprivation experiment by evaluating the decay in

139 ates of sleep homeostasis in sheep through a sleep deprivation experiment.

140 of genes that responded to subsequent total sleep deprivation from 122 to 856.

141 ne or two nights of recovery sleep following sleep deprivation fully restores brain and cognitive fun

142 vicanthis ansorgei, were aroused at night by sleep deprivation (gentle handling) or caffeine treatmen

143 was shown between the unrestricted sleep and sleep deprivation group (95% CI [3.4, 148.4], P = .04).

144 In the sleep deprivation group, BMI and central distribution of

145 differed between the unrestricted sleep and sleep deprivation groups (P = .04) in contrast to stable

146 Moreover, the adolescents with sleep deprivation had a lower median (interquartile rang

147 xposure to irregular light-dark patterns and sleep deprivation has been associated with beta amyloid

148 Sleep deprivation has been shown recently to alter emoti

149 Sleep deprivation has long been known to impair cognitio

150 Sleep deprivation has marked effects on food intake, shi

151 During sleep deprivation, homeostatic and circadian processes i

152 or delirium, including cognitive impairment, sleep deprivation, immobility and visual and hearing imp

153 Here, we demonstrate in humans that sleep deprivation impairs both viscerosensory brain (ant

154 Although previous work has indicated that sleep deprivation impairs hippocampal cAMP signaling, it

155 Sleep deprivation impairs the formation of new memories.

156 TyrRII levels rise following sleep deprivation in a Ca(2+)-dependent manner, promotin

157 full night of habitual sleep and a night of sleep deprivation in a repeated-measures crossover desig

158 Sleep deprivation in early night, but not late night, po

159 eview data on the psychotomimetic effects of sleep deprivation in healthy human beings and provide ev

160 nces alone may worsen pain, and experimental sleep deprivation in humans supports this claim.

161 urpose of duty-hour regulations is to reduce sleep deprivation in medical trainees, but their effects

162 iurnal rodent, the Grass rat, indicates that sleep deprivation in the early rest period induces phase

163 he model-builder was sleep deprived, whereas sleep deprivation in the instruction-giver predicted an

164 1 neurons are still activated in response to sleep deprivation in these mice but, in the absence of n

165 cific Nlg1 transcript variants is changed by sleep deprivation in three mouse strains.

166 Acute sleep deprivation increased sucrose self-administration

167 induced increase in alpha power by means of sleep deprivation increased the average duration of indi

168 reduced and fragmented sleep, while chronic sleep deprivation increases Abeta burden.

169 for a scientific commentary on this article.Sleep deprivation increases amyloid-beta, suggesting tha

170 We hypothesize that chronic sleep deprivation increases cerebral Abeta42 levels, whi

171 ew findings from our group reveal that acute sleep deprivation increases levels of tau in mouse brain

172 Using RNA-seq we show that sleep deprivation increases the differences in prefronta

173 Sleep deprivation increases the excitability of dorsal F

174 Lack of CIRBP indeed blunted the sleep-deprivation incurred changes in cortical expressio

175 ry pressures, and the deleterious effects of sleep deprivation, indicate that sleep serves a function

176 n of GS and innexin2 are increased following sleep deprivation, indicating that GS and innexin2 genes

177 Sleep deprivation induced a global increase in mGluR5 bi

178 Early night, but not late night, sleep deprivation induced a significant phase shift.

179 results suggest a possibility of normalizing sleep deprivation-induced abnormal reward seeking by tar

180 s at understanding the mechanisms underlying sleep deprivation-induced enhancement of reward seeking.

181 Finally, the sleep deprivation-induced increase in well established n

182 IMK-cofilin activation-signaling pathway for sleep deprivation-induced memory disruption and reductio

183 Conversely, mimicking sleep deprivation-induced reduction of rBLAp-vlNAc trans

184 bp knock-out (KO) mice to exhibit attenuated sleep-deprivation-induced changes in clock-gene expressi

185 Sleep deprivation induces changes in brain metabolism an

186 Sleep deprivation is a major source of morbidity with wi

187 However, sleep deprivation is an independent factor that also red

188 The sleep following sleep deprivation is longer and deeper, with an increase

189 Sleep deprivation is proposed to inhibit top-down-contro

190 ough it does not involve circadian shifts or sleep deprivation, it markedly alters feeding behaviors

191 the clinic: electroconvulsive shock therapy, sleep deprivation, ketamine, scopolamine, GLYX-13 and pi

192 Here we show, using flies and mice, that sleep deprivation leads to accumulation of reactive oxyg

193 The results suggest that sleep deprivation leads to changes in communicative perf

194 Sleep deprivation leads to increased hippocampal express

195 In unaffected sheep, sleep deprivation led to increased EEG delta (0.5-4 Hz)

196 Sleep deprivation (<8 hours of sleep per night) is assoc

197 e population into 2 groups: adolescents with sleep deprivation (<8 hours/night) and adolescents with

198 s in some frequency bands over the course of sleep deprivation may falsely indicate LRTC changes that

199 Furthermore, after sleep deprivation, mice with lesioned VTA(Vgat) neurons

200 ated, preventable circadian misalignment and sleep deprivation might underlie MVA risk increases.

201 These data support the use of the sleep deprivation model in combination with biomarkers w

202 These findings suggest that prolonged sleep deprivation modifies inflammatory and cholesterol

203 The adolescents with sleep deprivation (n = 257) compared with those with ade

204 Neither experimental sleep deprivation nor sleep restriction was associated w

205 Both sleep deprivation of at least 2 h/day (B = -0.96, 95% co

206 Sleep deprivation of HD model flies results in exacerbat

207 t frequent reasons for wanting to leave were sleep deprivation on a specific rotation (50.0%), an und

208 experimental study to examine the effects of sleep deprivation on advice taking in an estimation task

209 However, a clear effect of sleep deprivation on aggressive behaviors remains unclea

210 The Stockholm sleepy brain study: effects of sleep deprivation on cognitive and emotional processing

211 may underlie some of the negative effects of sleep deprivation on cognitive performance and is consis

212 We wanted to determine the effect of sleep deprivation on dendritic spines of hippocampal CA1

213 e, we examine the impact of brief periods of sleep deprivation on dendritic structure.

214 , we aimed to investigate effects of partial sleep deprivation on emotional contagion and mimicry in

215 extremes of sleep duration, and experimental sleep deprivation on genomic, cellular, and systemic mar

216 lecular mechanisms underlying the effects of sleep deprivation on HSCs, emphasizing the potentially c

217 and conversely, resilience) to the impact of sleep deprivation on memory formation.

218 while crucial to understanding the impact of sleep deprivation on performance in safety-critical task

219 metabolomics to examine the effect of acute sleep deprivation on plasma metabolite rhythms.

220 Objectives: We aimed to assess the effect of sleep deprivation on respiratory motor output and inspir

221 Recent studies on the effects of sleep deprivation on synaptic plasticity have yielded di

222 Therefore, we explored the influence of sleep deprivation on the human brain using two different

223 ise time-of-day variation and the effects of sleep deprivation on urinary metabolite profiles.

224 hanges in cognitive performance during acute sleep deprivation (one prolonged wake episode), chronic

225 then randomised to either one night of total sleep deprivation or a fourth night with 8-9 hours in be

226 uated the acute increase in sleep induced by sleep deprivation or bacterial infection.

227 odents, behavioral arousal induced either by sleep deprivation or caffeine during the sleeping period

228 ntions with a rapid onset of action--such as sleep deprivation or intravenous drugs (e.g., ketamine o

229 gain to disturbed endocrine parameters after sleep deprivation or restriction, neuroimaging studies r

230 Sleep deprivation, or prolonged wakefulness, interferes

231 lignment using a constant routine 24-h acute sleep-deprivation paradigm.

232 mouse model of CSR where mice underwent 18-h sleep deprivation per day for 5 consecutive days, we per

233 erving spontaneous eyelid closures following sleep deprivation permits nonintrusive arousal monitorin

234 m order: with exercise after each dose, with sleep deprivation preceding challenge, and with no inter

235 in hippocampal neurons during the course of sleep deprivation prevented these memory consolidation d

236 er transiently increasing cAMP levels during sleep deprivation prevents memory consolidation deficits

237 We find that acute sleep deprivation profoundly suppresses aggressive behav

238 ind with both measures that LRTCs decline as sleep deprivation progresses.

239 ocedures, new medications, sensory overload, sleep deprivation, prolonged bed rest, malnourishment, a

240 of TMS-evoked responses recorded over a 29 h sleep deprivation protocol conducted in young and health

241 We combined a partial sleep-deprivation protocol, pattern-based olfactory neur

242 al-sleep condition.Conclusions: One night of sleep deprivation reduces respiratory motor output by al

243 Here we show in mice that donor sleep deprivation reduces the ability of its haematopoie

244 imates and rodents it was found that, during sleep deprivation, regional 'sleep-like' slow and theta

245 nd sex in the multivariate regression model, sleep deprivation remained an independent predictor for

246 ein, we argue that experimentally controlled sleep deprivation represents a translational model syste

247 % CI, 22% to 62%; P = .001) for exercise and sleep deprivation, respectively.

248 Recovery of sleep after sleep deprivation restored the reconstitution potential

249 g behavioral impairments under conditions of sleep deprivation/restriction.

250 Sleep deprivation resulted in a higher A1AR availability

251 As a consequence, sleep deprivation resulted in similar processing of neut

252 However, only sleep deprivation resulting from activation of cholinerg

253 In contrast, sleep deprivation resulting from activation of octopamin

254 Sleep deprivation results in a sleep rebound.

255 Drug administration was preceded by 6 h of sleep deprivation (SD) ('high sleep pressure') or undist

256 Sleep deprivation (SD) affects cognitive functions such

257 x after 6-8 h of sleep, spontaneous wake, or sleep deprivation (SD) and after chronic ( approximately

258 Acute sleep deprivation (SD) can trigger or exacerbate psychos

259 Furthermore, chronic sleep deprivation (SD) increases Abeta plaques.

260 Sleep deprivation (SD) interferes with hippocampal struc

261 Sleep deprivation (SD) might be such a model as it has p

262 x of mice over a 3-d period, including a 6-h sleep deprivation (SD) on day 2.

263 Yet the effect of sleep deprivation (SD) on decision making and performanc

264 ersely, changes in behavioral state, such as sleep deprivation (SD) or arousal, can phase shift the c

265 ssant strategies, low-dose ketamine (KT) and sleep deprivation (SD) therapies, dramatically reduce de

266 ressant interventions, low-dose ketamine and sleep deprivation (SD) therapy, act within hours to robu

267 that whereas Hcrt(ko/ko) mice respond to 6-h sleep deprivation (SD) with a slow-wave sleep (SWS) EEG

268 Although different studies associated sleep deprivation (SD) with systemic inflammatory change

269 tary polyphenols promote memory in models of sleep deprivation (SD), stress, and neurodegeneration.

270 ice during undisturbed 24 h, and after a 6-h sleep deprivation (SD).

271 e resistant to the antidepressant effects of sleep deprivation (SD).

272 ers at baseline and during and after 12 h of sleep deprivation (SD).

273 of serotonin and dopamine in the brain upon sleep deprivation (SD).

274 s at understanding the mechanisms underlying sleep deprivation (SDe)-induced enhancement of reward se

275 Moreover, sleep deprivation significantly degrades the normally re

276 Sleep deprivation significantly impairs a range of cogni

277 tivity within somatosensory cortex following sleep deprivation significantly predicts this expansion

278 eating insomnia and suggests that laboratory sleep deprivation studies could serve to document the ef

279 By contrast, sleep deprivation studies using approaches avoiding nove

280 Sleep deprivation studies using novelty exposure as a me

281 cognitive deficits, that typically accompany sleep deprivation, such as the loss of mental flexibilit

282 task failure was significantly shorter after sleep deprivation than after normal sleep: (30 min [inte

283 -gain promoting high-calorie foods following sleep deprivation, the extent of which is predicted by t

284 as some sleep pressure correlates respond to sleep deprivation, the strongest electroencephalogram (E

285 homeostasis: in the recovery sleep following sleep deprivation there is a diminished increase in delt

286 for an individual's chronotype and degree of sleep deprivation to answer these questions.

287 ompared participants with one night of total sleep deprivation to participants with a night of regula

288 Total sleep deprivation (TSD) exerts strong modulatory effects

289 memory deficits following one night of total sleep deprivation (TSD) in 39 healthy adults in a contro

290 is context, we used a laboratory-based total sleep deprivation (TSD) paradigm to investigate psychomo

291 table with repeated exposures to acute total sleep deprivation (TSD) within a short-time interval (we

292 and neurocognitive performance during total sleep deprivation (TSD).

293 Recovery from sleep deprivation was associated with a decrease in A1AR

294 In addition, the homeostatic response to sleep deprivation was greatly attenuated with disease pr

295 participants who underwent a night of total sleep deprivation were replicated in an independent data

296 This becomes particularly evident during sleep deprivation, when the interplay between these stat

297 ness and impairs the homeostatic response to sleep deprivation, whereas tonic optogenetic stimulation

298 igh-density EEG after normal sleep and after sleep deprivation while participants observed a Necker c

299 sion is selectively weakened following acute sleep deprivation, whose restoration normalizes reward s

300 We conducted a 2 (sleep deprivation: yes vs. no) x2 (competency of advisor