ライフサイエンスコーパス: sleep disruption

1 y, as well as pan-metabolome consequences of sleep disruption.

2 nsolidation before subjecting them to 6-h of sleep disruption.

3 ely studied patient-reported factors causing sleep disruption.

4 y contributing to circadian misalignment and sleep disruption.

5 n the completeness of recovery after chronic sleep disruption.

6 reathing instability and respiratory-related sleep disruption.

7 le measured hyperarousal symptoms, including sleep disruption.

8 assessment for restless leg syndrome-related sleep disruption.

9 gitation/sedation, delirium, immobility, and sleep disruption.

10 (US) and two nights of forced awakening (FA) sleep disruption.

11 efore arousals suggests its participation in sleep disruption.

12 e potential to cause per se narcoleptic-like sleep disruption.

13 acterized by recurrent nocturnal hypoxia and sleep disruption.

14 leep associated with oxygen desaturation and sleep disruption.

15 e, bowel/bladder and sexual dysfunction, and sleep disruption.

16 termine the effect of environmental noise on sleep disruption.

17 elated epileptic activity is associated with sleep disruption.

18 neously addressing comorbid symptoms such as sleep disruption.

19 regulate stress-induced memory deficits and sleep disruptions.

20 hey generally suggest modest and nonspecific sleep disruptions.

21 g neural mechanisms that explain age-related sleep disruption?

22 re reported: 1) patient-reported reasons for sleep disruption, 2) patient-reported ratings of potenti

23 anisms linking non-rapid-eye-movement (NREM) sleep disruption, Abeta, and AD; (ii) a role for NREM sl

24 ical findings to humans by examining whether sleep disruption alters morphine's analgesic and hedonic

25 Although a clinical association between sleep disruption and AD has long been appreciated, emerg

26 C1 cell activation likely contributes to the sleep disruption and adverse autonomic consequences of s

27 Despite the co-occurrence of sleep disruption and anxiety disorders, the impact of sl

28 e and central types of sleep apnea result in sleep disruption and arterial oxyhemoglobin desaturation

29 Sleep disruption and arterial oxyhemoglobin desaturation

30 echanisms underlying the interaction between sleep disruption and behavior remain poorly understood.

31 striatal DA release and the extent to which sleep disruption and behavioral maladaptation manifest d

32 , and offer a mechanism for the link between sleep disruption and blood glucose dysregulation in type

33 sis of a direct pathological role of PLMS in sleep disruption and can be important for the discussion

34 athways of injury common to various forms of sleep disruption and consider the implications of this i

35 often accompanied by severe encephalopathy, sleep disruption and delirium that strongly correlate wi

36 ffect size indicating an association between sleep disruption and depressive symptoms in children and

37 onfused about the time of day and experience sleep disruption and fatigue.

38 Comorbid medical problems, such as sleep disruption and growth suppression, continue to be

39 logy with both non-rapid eye movement (NREM) sleep disruption and memory impairment in older adults.

40 latonin supplementation for the treatment of sleep disruption and other neurological diseases such as

41 g evidence of a possible association between sleep disruption and the neurodegenerative process sugge

42 Here, we summarize the human response to sleep disruption and then discuss recent findings in ani

43 xplored cross-sectional associations between sleep disruption and tryptophan-kynurenine (T/K) pathway

44 cancer-associated changes in behavior (e.g., sleep disruption) and physiology (e.g., glucocorticoid d

45 topic dermatitis (AD) experience significant sleep disruption, and clinically, the disease is noted t

46 dverse effects, including movement problems, sleep disruption, and gastrointestinal problems (eg, nau

47 arly-onset patients had more energy, minimal sleep disruption, and greater suicidality, while typical

48 eriod for the mice, slow-wave EEG dominance, sleep disruption, and hypersensitivity to auditory stimu

49 Inability to communicate, sleep disruption, and limitations on visiting were parti

50 eexperiencing trauma, anxiety, hyperarousal, sleep disruption, and nightmares have been reported.

51 nologic consequences of circadian rhythm and sleep disruption, and persisting knowledge gaps in the f

52 ysfunction as a potential link between mTBI, sleep disruption, and posttraumatic morbidity.

53 han 40 million Americans suffer from chronic sleep disruption, and the development of effective treat

54 han 40 million Americans suffer from chronic sleep disruption, and the development of effective treat

55 Sleep disruption appears to be a core component of Alzhe

56 ovascular disease, traumatic CNS injury, and sleep disruption are established and emerging risk facto

57 mechanisms that control prolonged effects of sleep disruption are not understood.

58 Sleep disruptions are among the most commonly reported s

59 By reframing adolescent sleep disruption as a key factor in psychiatric morbidit

60 with impaired NREM SWA, these data implicate sleep disruption as a mechanistic pathway through which

61 ii) the potential diagnostic utility of NREM sleep disruption as a new biomarker of AD; and (iv) the

62 ruption, Abeta, and AD; (ii) a role for NREM sleep disruption as a novel factor linking cortical Abet

63 ed in many atopic diseases that can underlie sleep disruptions as a consequence of the presence of no

64 ear during tests conducted immediately after sleep disruption, as well as 24 h later.

65 Clinicians need to consider that the chronic sleep disruption associated with nightmares may affect t

66 promised mental health could be a marker for sleep disruption at the post-COVID period.

67 These data demonstrate that sleep disruption attenuates morphine analgesia in humans

68 adequate interventions to prevent and treat sleep disruption because of their high relevance to our

69 survivors suffering from moderate or greater sleep disruption between 2 and 24 months after surgery,

70 For cancer, cannabinoids improved sleep disruption, but had gastrointestinal adverse event

71 t from normalization of chronic pain-related sleep disruption by KOR antagonism.

72 idates conceptual networks of knowledge, how sleep disruption can signal suicidal tendencies a month

73 ine a model where glymphatic dysfunction and sleep disruption caused by mTBI may have an additive eff

74 mproved with sleeping drugs, suggesting that sleep disruption contributes to their neurological decli

75 and clinical evidence suggests that chronic sleep disruption (CSD) leads to heightened pain sensitiv

76 Chronic sleep disruption (CSD), from insufficient or fragmented

77 Nocturnal sleep disruption develops in Alzheimer disease (AD) owin

78 quality of life caused by intense pruritus, sleep disruption, dietary and nutritional concerns, and

79 Preclinical studies demonstrate that sleep disruption diminishes morphine analgesia and modul

80 evels of depression, anxiety, fatigue, pain, sleep disruption, dissociation and obsessiveness.

81 Patients reported less sleep disruptions due to urination and fewer episodes of

82 tion and those with more negative affect and sleep disruption during marijuana withdrawal were more l

83 Pain disrupts sleep and conversely, sleep disruption enhances pain, but the underlying mecha

84 r the functional consequences of age-related sleep disruption, focusing on memory impairment as an ex

85 Persistent sleep disruptions following withdrawal from abused drugs

86 the MICU appeared to be more susceptible to sleep disruptions from environmental factors than patien

87 hoea (2.25 (1.33 to 3.81)), had no effect on sleep disruption (GRADE=high), reduced seizures across d

88 Sleep disruption has deleterious effects, even in normal

89 observed for depression, anger, anxiety, and sleep disruption (Hedges g = 0.3-0.5; all P < .03).

90 rat model is associated with large long-term sleep disruption, however, the vehicle, DMSO/PEG had as

91 with PTCHD1 deletion show symptoms of ADHD, sleep disruption, hypotonia, aggression, ASD, and ID.

92 urst; however, the effects of other forms of sleep disruption (i.e. spontaneous arousals and apnoea-i

93 e, and delirium were factors associated with sleep disruption identified in available studies.

94 Interestingly, there are reports that sleep disruption immediately after a traumatic experienc

95 elopmental function of sleep and reveals how sleep disruption impacts key aspects of brain developmen

96 CU exposures were used to describe causes of sleep disruption in a PICU.

97 ent factors associated with sound levels and sleep disruption in a range of representative ICUs.

98 Itch was thought to predominantly drive sleep disruption in AD.

99 gitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU.

100 gitation/sedation, delirium, immobility, and sleep disruption in adults admitted to the ICU.

101 Moreover, early life sleep disruption in animal models causes long-lasting ch

102 Numerous risk factors for sleep disruption in critically ill adults have been desc

103 ynchrony, a characteristic of shift work and sleep disruption in humans, also leads to metabolic path

104 ght (12-h) mechanical stimulation or chronic sleep disruption in insomniac mutants, broadly elevates

105 sleep loss, we quantified a new procedure of sleep disruption in mice by a week of consecutive sleep

106 the CO(2) -arousal reflex is associated with sleep disruption in obstructive sleep apnoea.

107 The etiology of sleep disruption in patients in intensive care units (IC

108 With aging, there is evidence for sleep disruption in PS19 mice, characterized by reduced

109 nderstanding the neural mechanism underlying sleep disruption in response to environmental perturbati

110 Such findings suggest that sleep disruption in the elderly, mediated by structural

111 nts; and (2) the environmental etiologies of sleep disruption in the ICU are multifactorial.

112 c review of all risk factors associated with sleep disruption in the ICU setting.

113 ted, and ICU-related factors associated with sleep disruption in the ICU.

114 zure activity, rapid sleep onset and reduced sleep disruption in the other recording.

115 mental health, and the rising prevalence of sleep disruption in vulnerable populations.

116 dings may help identify treatments to reduce sleep disruption in WWH by targeting residual inflammati

117 r understanding of the mechanisms underlying sleep disruptions in AS.

118 sability (ID), pervasive seizures and severe sleep disruption, including recurring hospitalizations.

119 delayed or incomplete recovery after chronic sleep disruption, including sustained vigilance and epis

120 APPswe/PS1dE9 (APP) mice exhibit sleep disruptions, including reductions in non-rapid eye

121 ion, mediation analyses further defined that sleep disruption independently contributes to inflammati

122 anation for these findings is that immediate sleep disruption interferes with consolidation of fear m

123 exposed to high sound levels and substantial sleep disruption irrespective of factors including previ

124 Sleep disruption is a core feature of PTSD supporting th

125 Sleep disruption is a recognized feature of all anxiety

126 In model organisms, sleep disruption is associated with pericyte dysfunction

127 ENT In the light of increasing evidence that sleep disruption is crucially involved in the progressio

128 Sleep disruption is prevalent in patients with cancer an

129 er emerging studies suggest that age-related sleep disruption may be one key factor that renders the

130 a support a neuropathological model in which sleep disruption may contribute to the maintenance and/o

131 ing that like many other stressors, extended sleep disruption may lead to a state of sustained microg

132 Sleep disruption measures were standardized, and estimat

133 In cross-sectional models, actigraphic sleep-disruption measures (wake after sleep onset, fragm

134 Actigraphic sleep-disruption measures were also associated with odds

135 s in circadian rhythms may contribute to the sleep disruption observed in older adults.

136 Circadian rhythm and sleep disruptions occur frequently in individuals with a

137 EMENT Alzheimer's disease is associated with sleep disruption, often before significant memory declin

138 The APOE genotype modulates the effect of sleep disruption on AD risk, suggesting a possible link

139 d education, the detrimental consequences of sleep disruption on mental health, and the rising preval

140 strategies to reduce the adverse effects of sleep disruption on metabolic health are provided and fu

141 Objectives: In this study (SLEEWE [Effect of Sleep Disruption on the Outcome of Weaning from Mechanic

142 In parallel, sleep disruption or hyperlipidemia and cardiometabolic s

143 e to daily differences in physical activity, sleep disruption, or core body temperature (CBT).

144 Sleep disruptions promote increases of amyloid B (AB) an

145 This sleep disruption regimen also increased levels of mRNA e

146 possibility that the effects of our delayed sleep disruption regimen are not due to disruption of me

147 We find that sleep disruptions resulting in energy deficit through in

148 Potential ICU sleep disruption risk factors were categorized into thre

149 Here, we show that in mice, sleep disruption (SD) in adolescence, but not in adultho

150 Here, we investigated the impact of acute sleep disruption (SD) on brain cancer-related pathways i

151 rimental studies of these different forms of sleep disruption show deranged physiology from subcellul

152 dation is more susceptible to the effects of sleep disruption than is the acquisition (learning) of s

153 hildren undergoing polysomnography, had less sleep disruption than those in a PICU despite sleeping i

154 may affect the degree of hypoxic stress and sleep disruption that occurs in response to upper airway

155 Though stress causes complex sleep disruptions that are different in females and male

156 ICANCE STATEMENT Several studies have linked sleep disruption to the progression of Alzheimer's disea

157 Overall sleep disruption was not different across four PICUs or

158 Level of sleep disruption was scored by Likert scale, with higher

159 Total hyperarousal symptoms and sleep disruption were not significantly associated with

160 We used a phase advance model of sleep disruption where sleep initiation is scheduled in

161 rceived dietary quality at work (p = 0.003), sleep disruptions which impacted their consumption of a

162 ral dementia are associated with substantial sleep disruption, which may accelerate cognitive decline