ライフサイエンスコーパス: sleep disturbance

1 , implementing nighttime routines to address sleep disturbances).

2 tumor growth, malaria, hypoxia, stress, and sleep disturbances).

3 centrating, irritability, muscle tension, or sleep disturbances).

4 sordered temperature regulation, and induces sleep disturbance.

5 er such association is related to fatigue or sleep disturbance.

6 mor and symptoms of fatigue, depression, and sleep disturbance.

7 delay or intellectual disability, and severe sleep disturbance.

8 able to a positive energy balance because of sleep disturbance.

9 life, an association not explained by VMS or sleep disturbance.

10 ain, poor nutrition, sensory impairment, and sleep disturbance.

11 oth the subjective and objective measures of sleep disturbance.

12 The PPND kindred showed severe sleep disturbance.

13 None had a history of depression or sleep disturbance.

14 nce of a prior depressive episode along with sleep disturbance.

15 silience at work compared with those without sleep disturbance.

16 L and self-reported usual sleep duration and sleep disturbance.

17 cial status, social support, neuroticism, or sleep disturbance.

18 on, anxiety, functional status, fatigue, and sleep disturbance.

19 ) have impaired receptor function and showed sleep disturbances.

20 to new treatment strategies for a variety of sleep disturbances.

21 ay, motor dysfunction, autistic features and sleep disturbances.

22 e disease accompanied by atopy, fatigue, and sleep disturbances.

23 al disorder whose non-motor symptoms include sleep disturbances.

24 (ISI), a validated instrument for assessing sleep disturbances.

25 with normal sleep-wake regulation and cause sleep disturbances.

26 earliest abnormalities in premanifest HD is sleep disturbances.

27 accompanied by fatigue, memory problems, and sleep disturbances.

28 traffic noise is associated with stress and sleep disturbances.

29 a questionnaire including information about sleep disturbances.

30 attention deficits, affective disorders, and sleep disturbances.

31 ikely substrate for some of these persistent sleep disturbances.

32 culoskeletal injuries, anxiety disorders and sleep disturbances.

33 retardation, loss of motor coordination, and sleep disturbances.

34 about sensory and motor symptoms leading to sleep disturbances.

35 associated with annoyance and, potentially, sleep disturbances.

36 arthritis, would be expected to show similar sleep disturbances.

37 fatigue or somnolence (35 patients [41.1%]), sleep disturbance (12 [14.1%]), and urinary symptoms (8

38 research and has been regarded as a typical sleep disturbance [2-4].

39 s high as 76.2% of the women reported global sleep disturbance, 30.6% endorsed snoring, 24.3% sleep <

40 n, 51.4) and cervical cancer (anxiety, 53.2; sleep disturbance, 53.4).

41 t symptoms/signs were radicular pain (100%), sleep disturbances (75.3%), erythema migrans (59.7%), he

42 mood (219 [47%]), catatonia (137 [30%]), and sleep disturbance (97 [21%]).

43 l disabilities, behavioral abnormalities and sleep disturbances, a majority of children with SMS also

44 ncluded positive symptoms, bizarre thinking, sleep disturbances, a schizotypal disorder, level of fun

45 Here we show that chronic REM sleep disturbance, achieved in mice by chronic sleep fra

46 o sensory abnormality, attention deficit and sleep disturbance across multiple neurodevelopmental dis

47 This study is the first to demonstrate that sleep disturbance acts as an independent risk factor for

48 ple mechanisms have been identified by which sleep disturbances adversely affect cardiovascular struc

49 ext day in healthy subjects, suggesting that sleep disturbances alone may worsen pain, and experiment

50 Sleep disturbances, alterations of sleep architecture, a

51 associated with circadian dysregulation and sleep disturbances, although a causal relationship canno

52 his study identified two distinct classes of sleep disturbance among novice nurses during the first 2

53 o identify latent classes of trajectories of sleep disturbance among novice nurses during the first 2

54 nd insomnia and to identify risk factors for sleep disturbance among patients with asthma, in a large

55 lth workers may consider routinely assessing sleep disturbances among HIV-infected patients, especial

56 oved understanding of the mechanisms linking sleep disturbance and Alzheimer's disease risk could fac

57 ence of a bidirectional relationship between sleep disturbance and anxiety-related disorders, and pro

58 While sleep disturbance and circadian dysregulation are critic

59 Sleep disturbance and fatigue are commonly reported amon

60 Treatment options for sleep disturbance and future directions for research are

61 e and autonomic neural underpinnings linking sleep disturbance and immunity and the reciprocal links

62 l melatonin were found to be associated with sleep disturbance and increased disease severity in chil

63 n of targets for prevention, given that both sleep disturbance and inflammatory activation might be m

64 Sleep disturbance and long sleep duration, but not short

65 e events such as weight gain, skin thinning, sleep disturbance and neuropsychiatric disorders may occ

66 emerge regarding the pervasive link between sleep disturbance and psychiatric conditions, including

67 Eczema is associated with high rates of sleep disturbance and quality-of-life impairment.

68 A users may be related, at least in part, to sleep disturbance and suggest that cognitive deficits in

69 ge, suggesting a causal relationship between sleep disturbance and symptomatic progression in the neu

70 r and their FCs experience similar levels of sleep disturbance and that both groups could benefit fro

71 ied the association between adult eczema and sleep disturbance and their impact on overall health and

72 ogic study has examined the relation between sleep disturbance and thyroid cancer risk.

73 primary research articles that characterized sleep disturbance and/or sleep duration or performed exp

74 regiver stress can lead to psychological and sleep disturbances and changes in caregivers' physical h

75 presents a range of premotor signs, such as sleep disturbances and cognitive decline, which are key

76 inical studies suggest a correlation between sleep disturbances and cognitive dysfunction in patients

77 Sleep disturbances and cognitive impairment are common i

78 rapies to treat and potentially prevent both sleep disturbances and cognitive impairment.

79 Parkinson's disease (PD) display significant sleep disturbances and daytime sleepiness.

80 ated VS activity increases, the link between sleep disturbances and depression decreases.

81 S activity increased the association between sleep disturbances and depressive symptoms decreased.

82 These children also displayed more frequent sleep disturbances and episodes of aggression.

83 the management of chronic pain comorbid with sleep disturbances and for the management of postoperati

84 ent fish consumption is associated with less sleep disturbances and higher IQ scores in schoolchildre

85 However, it is not known whether sleep disturbances and metabolic abnormalities underlyin

86 robust evidence for the relationship between sleep disturbances and psychiatric outcomes and symptoms

87 hronic inflammatory disorder associated with sleep disturbances and quality-of-life impairment.

88 tudies have examined the association between sleep disturbances and semen quality.

89 the first study to find associations between sleep disturbances and semen quality.

90 Positive associations between sleep disturbances and SPD were generally stronger among

91 ssion spectrum, psychosis spectrum, anxiety, sleep disturbances and stress) across community-dwelling

92 Despite a clear link between sleep disturbances and subsequent disturbances in mood,

93 chanisms underlying the relationship between sleep disturbances and suicide.

94 The interaction between sleep disturbances and VS activity was robust to the inc

95 terest-muscle-related, erectile dysfunction, sleep disturbance, and cognitive impairment-and analysed

96 Results also suggest that fatigue, sleep disturbance, and depression may stem from distinct

97 increased craving for sweet foods, increased sleep disturbance, and had worsening bodily pain.

98 igher levels of depression, morning fatigue, sleep disturbance, and lower levels of evening fatigue r

99 essure (BP), including chronic inflammation, sleep disturbance, and mental health comorbidity.

100 Headache, gastrointestinal upset, sleep disturbance, and sympathetic nervous system arousa

101 , asthma), major quality-of-life impairment, sleep disturbance, and the use of potent topical and som

102 sion, depression recurrence was predicted by sleep disturbance, and this association was independent

103 Major exposures were depressive, anxiety, sleep disturbance, and vasomotor symptoms and menopause

104 The authors found that depressive, anxiety, sleep disturbance, and vasomotor symptoms did not accoun

105 followed by baseline anxiety level, baseline sleep disturbance, and--for a minority of patients--the

106 used and identified five classes of fatigue, sleep disturbances, and allergic disorders.

107 an association between short sleep duration, sleep disturbances, and circadian desynchronisation of s

108 lterations that include depression, fatigue, sleep disturbances, and cognitive dysfunction.

109 more than just pain; depression and anxiety, sleep disturbances, and decision-making abnormalities al

110 to explore associations between chronotype, sleep disturbances, and metabolic components.

111 erms of more severe nighttime coughing, more sleep disturbances, and more days with runny nose (all P

112 musculoskeletal pain and associated fatigue, sleep disturbances, and other cognitive and somatic symp

113 ytime sleepiness (EDS), cataplexy, nighttime sleep disturbances, and REM-sleep-related phenomena (sle

114 SD have yielded mixed findings regarding REM sleep disturbances, and they generally suggest modest an

115 r patients age 65 to 84 years reported lower sleep disturbance, anxiety, and depression, and better c

116 , but still positive, therapeutic benefit on sleep disturbance, anxiety, appetite loss, physical symp

117 res, delayed language and motor development, sleep disturbances, anxiety-like behaviour, severe cogni

118 ss, headache, cognitive processing speed and sleep disturbance are associated with tinnitus.

119 Fatigue, depression, and sleep disturbance are common adverse effects of cancer t

120 Nurses with sleep disturbance are more vulnerable to stressful stimu

121 e risk for depression.SIGNIFICANCE STATEMENT Sleep disturbances are a common risk factor for depressi

122 ms such as repetitive speech, wandering, and sleep disturbances are a core clinical feature of Alzhei

123 Prompt diagnosis and treatment of sleep disturbances are advocated and may improve quality

124 However, sleep disturbances are associated with a wide range of p

125 Sleep disturbances are associated with hormonal imbalanc

126 Prior research suggests that sleep disturbances are associated with increased risk of

127 Sleep disturbances are associated with poor health outco

128 Sleep disturbances are common maladies associated with h

129 Although sleep disturbances are commonly cited as critical risk f

130 Sleep disturbances are commonly found in trauma-exposed

131 Sleep disturbances are increasingly recognized as a comm

132 Sleep disturbances are recognized as a common nonmotor c

133 Sleep disturbances are reportedly common among persons i

134 Our results indicated that sleep disturbances are statistically significant, yet we

135 The hypothesis that rapid eye movement (REM) sleep disturbances are the hallmark of posttraumatic str

136 estions about the practicality of relying on sleep disturbances as warning signs for imminent suicide

137 leep, abnormal sleep-wake transition and non-sleep disturbances as well as lab tests in Chinese fatal

138 all adults older than 60 years of age report sleep disturbance, as characterised either by reports of

139 ry treatment with corticosteroids, pain, and sleep disturbance, as well as psychosocial factors inclu

140 ute to phenotypes such as memory defects and sleep disturbance associated with FXS.

141 Chronic sleep disturbances, associated with cardiometabolic dise

142 nd 24 months, by loss of sexual interest and sleep disturbance at 6 months, and by vaginal dryness up

143 asurement point tended to report more severe sleep disturbance at prior measurements.

144 e measures of the occurrence and severity of sleep disturbance at the initiation of RT.

145 ease progresses and cognitive changes ensue, sleep disturbances become even more debilitating.

146 Despite sleep disturbance being a common complaint in individual

147 currence of clinically significant levels of sleep disturbance between patients and their FCs that ra

148 PH and Alzheimer's disease (AD) both exhibit sleep disturbances, build-up of brain metabolic wastes a

149 Sleep disturbance, but not VMS, was independently associ

150 tion to routine and systematic assessment of sleep disturbance by oncology clinicians, interventions

151 Mouse models for human sleep disturbances can be powerful due to the accessibil

152 ms of opiate withdrawal are well-documented, sleep disturbances caused by chronic opioid exposure and

153 eep measures are needed to determine whether sleep disturbance causes or accelerates Alzheimer diseas

154 eading to a neurodevelopmental syndrome with sleep disturbance, cerebellar atrophy, and facial dysmor

155 cient times it is known that melancholia and sleep disturbances co-occur.

156 e in women when vasomotor symptoms (VMS) and sleep disturbance commonly disrupt QOL.

157 culoskeletal injuries, anxiety disorders and sleep disturbances compared to less healthy work environ

158 and behaviours, it is unclear to what degree sleep disturbances confer risk for suicide.

159 Accumulating evidence shows that sleep disturbance contributes to cognitive decline and m

160 elopmental delays, behavioral abnormalities, sleep disturbance, craniofacial and skeletal abnormaliti

161 cluding 7 clinical features (breathlessness, sleep disturbance, cyanosis, venous dilatation, paresthe

162 l sequelae of breast cancer, namely fatigue, sleep disturbance, depression, and cognitive impairment.

163 endpoints including cardiovascular disease, sleep disturbance, depression, and psychosocial stress.

164 Older adults have high rates of sleep disturbance, die by suicide at disproportionately

165 se events (self-reported breathing problems, sleep disturbances, drowsiness or tiredness, nausea, swe

166 Nonocular risk factors included sleep disturbances (eg, sleep apnea and insomnia), menta

167 articipants self-reported sleep duration and sleep disturbances (eg, trouble falling and staying asle

168 with the nonmotor symptoms of PD, including sleep disturbances, emotional changes such as anxiety an

169 Brain abnormalities, behavioral problems, sleep disturbance, epilepsy, hypotonia, visual problems,

170 Untreated sleep disturbances following TBI can lead to serious con

171 gy mechanisms underscore the implications of sleep disturbance for inflammatory disease risk, and pro

172 amined various sleep parameters ranging from sleep disturbances (general, perceived sleep quality, sl

173 a, loss of appetite, depression, anxiety, or sleep disturbance) >/= 4 of 10 on the Edmonton Symptom A

174 rch over the past decade has documented that sleep disturbance has a powerful influence on the risk o

175 Sleep disturbance has been found to be associated with n

176 Sleep disturbances have been shown to cause headaches in

177 depression and emotional lability, fatigue, sleep disturbance, head drop, prevention of deep venous

178 kinson's disease, global polyuria, insomnia, sleep disturbances, heart failure, anxiety, and depressi

179 of a college degree, higher anxiety, greater sleep disturbance, heavy alcohol use, current tobacco us

180 o probe biological phenotypes of PTSD (e.g., sleep disturbances, hippocampal and fear-circuit dysfunc

181 is associated with subjective and objective sleep disturbances; however, it is not known whether str

182 d the prevalence and factors associated with sleep disturbance in a large cohort of HIV-infected pati

183 public health problem and is the most common sleep disturbance in both adults and children.

184 occurrence rates for and severity ratings of sleep disturbance in patient-family caregiver (FC) dyads

185 er, appropriate evaluation and management of sleep disturbance in patients with bipolar illness is fu

186 current report provides an updated review of sleep disturbance in posttraumatic stress disorder and a

187 study aims to characterize the nature of the sleep disturbance in PPND and compare these findings to

188 haracteristics and physiological features of sleep disturbance in specific DSM anxiety-related disord

189 Tests of mediation implicated baseline sleep disturbance in the cognitive decline seen during s

190 polysomnography, we found that the temporary sleep disturbance in the first sleep experimental sessio

191 l and longitudinal analyses, as well as with sleep disturbances in cross-sectional analyses.

192 social threats can drive the development of sleep disturbances in humans, which can contribute to th

193 Sleep disturbances in Huntington's disease may be delete

194 promote increased sleep drive may alleviate sleep disturbances in individuals with AS.

195 ty and a potential mechanism contributing to sleep disturbances in Parkinson's disease.

196 Sleep disturbances in people living with SCI are associa

197 duration, motor severity and complications, sleep disturbances, in particular excessive daytime somn

198 ociated symptom (pains, dizziness, headache, sleep disturbance, inability to relax, irritability) tha

199 Sleep disturbances including insomnia independently cont

200 o are abstinent long-term present persistent sleep disturbances, including a longer latency to fall a

201 inical manifestations in all 5 patients were sleep disturbances, including insomnia, laryngeal strido

202 upported by advances in our understanding of sleep disturbance-induced increases in systemic inflamma

203 zard ratios and 95% confidence intervals for sleep disturbance (insomnia and sleep duration) and risk

204 Sleep disturbances interact with common mental disorders

205 lead to more severe prodromal symptoms (e.g. sleep disturbance, irritability etc.).

206 Sleep disturbance is associated with activation of syste

207 Sleep disturbance is associated with inflammatory diseas

208 Sleep disturbance is common in bipolar disorder.

209 Sleep disturbance is common in children with atopic derm

210 relationship between alcohol consumption and sleep disturbance is complex.

211 Prevalence of sleep disturbance is high in this large Chinese cohort.

212 Sleep disturbance is important because it impairs qualit

213 Clinical and animal studies suggest that sleep disturbance is significantly associated with disru

214 Sleep disturbance is strongly associated with diabetes,

215 However, the underlying cause of these sleep disturbances is not well understood.

216 Limited recovery of sleep disturbances is seen in AUD within the first 30 da

217 ults not only demonstrate that selective REM sleep disturbance leads to hyperactivity of mHb ChNs, bu

218 The type of sleep disturbance may also vary according to the number

219 a key molecular substrate through which REM sleep disturbance may alter affect regulation.

220 For the depression-alone group, sleep disturbance may partially explain the negative imp

221 Similarly, treatment of sleep disturbance may serve as both a target of treatmen

222 spindle, and ripple events, indicating that sleep disturbances may be associated with state-dependen

223 n patients with Parkinson's disease but that sleep disturbances may first need to be corrected.

224 e medication (RR 3.46; 95% CI 2.79 to 4.30), sleep disturbance (MD -7.29; 95% CI -8.23 to -6.35) and

225 operative ileus, anxiety/mood disorders, and sleep disturbance) met all inclusion criteria.

226 astrointestinal upset/diarrhea, restlessness/sleep disturbances, minor wheezing, and cold extremities

227 The founder mutants exhibited sleep disturbances, motor deficits and increased repetit

228 Sleep disturbances negatively impact numerous functions

229 Neither sleep disturbances nor sleep duration was associated wit

230 insight into epigenetic-based regulation of sleep disturbances observed in neurodegenerative disease

231 Paradoxically, headache, facial pain, and sleep disturbance occurred significantly more frequently

232 Sleep disturbance occurs in most patients with delusions

233 ted VS activity would moderate the effect of sleep disturbances on depression in a large cohort of yo

234 e increasingly points to the large impact of sleep disturbances on public health.

235 ects model to analyse the overall effects of sleep disturbances on suicidal ideation, attempts, and d

236 ther symptoms, for symptoms such as profound sleep disturbance or psychotic symptoms may dominate the

237 es would also be helpful to identify whether sleep disturbances (or improvement of sleep quality) can

238 In acute sleep disturbance, oral administration of glycine-induce

239 the development of nonspecific symptoms and sleep disturbances over time.

240 CPM levels might be attributed, in part, to sleep disturbance (P=0.04).

241 rom observational studies support a role for sleep disturbances (particularly for sleep duration, sle

242 Sleep disturbance, particularly REM sleep disturbance, p

243 s converge in demonstrating a broad range of sleep disturbances, particularly longer duration and var

244 interference, fatigue, anxiety, depression, sleep disturbance, physical function, ability to partici

245 by examining the inter-relationships between sleep disturbance, physical symptoms, emotional problems

246 ent study sought to test the hypothesis that sleep disturbance plays a role in cognitive deficits in

247 with prior depression, it is unclear whether sleep disturbance predicts depression recurrence indepen

248 Sleep disturbance, particularly REM sleep disturbance, profoundly impacts emotion regulation

249 Mild sleep disturbance reduced sleep and increased c-fos expr

250 Sleep disturbance remains an independent correlate of lo

251 were two-fold: 1) to describe the pattern of sleep disturbances reported in a large sample of childre

252 tributing to the increased susceptibility to sleep disturbances reported in women.

253 ics were used to characterize the pattern of sleep disturbances reported, while structural equation m

254 Sleep disturbances represent one risk factor for depress

255 Spasticity can cause pain, fatigue and sleep disturbances; restrict daily activities such as wa

256 h Sleep Quality Index (PSQI) and the General Sleep Disturbance Scale (GSDS) and wore wrist actigraphs

257 p disturbance was assessed using the General Sleep Disturbance Scale.

258 Men with a high level of sleep disturbance (score >50) had a 29% (95% confidence

259 Sleep disturbances (SD) are the most impactful and commo

260 -analysis was to clarify the extent to which sleep disturbances serve as risk factors (i.e., longitud

261 Further, these sleep disturbances should be mitigated by analgesic ther

262 Sleep disturbances showed an inverse U-shaped associatio

263 men (2008-2011), Jensen et al. reported that sleep disturbances showed inverse U-shaped associations

264 t several hours later generates a pattern of sleep disturbances similar to that observed in stress-in

265 s a numerically greater incidence of nausea, sleep disturbance, skin reactions, constipation, and dep

266 Here, we assess global evidence linking sleep disturbance, sleep duration, and inflammation in a

267 unity, with consideration of the dynamics of sleep disturbance, sleep restriction, and insomnia on (a

268 significant interactions between eczema and sleep disturbances such that eczema associated with fati

269 in the LH and ameliorated the ppDIO-induced sleep disturbances, suggesting the therapeutic potential

270 ia, problems with gastrointestinal motility, sleep disturbances, sympathetic denervation, anxiety, an

271 esia in intensive care units associated with sleep disturbances, tachycardia, pulmonary complications

272 essive phase of bipolar illness is marked by sleep disturbance that may be amenable to somatic therap

273 onstrated to be associated with insomnia and sleep disturbances that affect perception of pain, produ

274 the states of sleep is responsible for those sleep disturbances that arise as a consequence of hypoxi

275 However, little is known about the sleep disturbances that occur in adult eczema.

276 Finally, we review the latest literature on sleep disturbances that persist or develop after critica

277 dividuals with Angelman syndrome (AS) suffer sleep disturbances that severely impair quality of life.

278 After adjustment for VMS and sleep disturbance, the comorbid group continued to have

279 ty Index) were used to assess sleep quality, sleep disturbances, time asleep, and time in bed.

280 ch include discussion of the contribution of sleep disturbance to depression and especially inflammat

281 and anxiety tend to lump different forms of sleep disturbance together.

282 ep duration, and examined joint effects with sleep disturbance traits and a coronary artery disease g

283 Other common symptoms such as mood changes, sleep disturbances, urinary incontinence, cognitive chan

284 Sleep disturbance was assessed using the General Sleep D

285 Sleep disturbance was associated with higher levels of C

286 Sleep disturbance was more frequently reported by CD sub

287 Sleep disturbance was not associated with LTL in our stu

288 The rate of reports of sleep disturbance was significantly lower among particip

289 The 2-year trajectories of sleep disturbance were classified into two distinct grou

290 ability (anger), concentration deficits, and sleep disturbance were found.

291 l; 6 = very much), nonspecific symptoms, and sleep disturbances were assessed by questionnaire.

292 Sleep disturbances were assessed on the basis of a modif

293 Sleep disturbances were associated with several factors

294 Sleep disturbances were observed in 43.1% of patients.

295 es of alcohol craving and mood, anxiety, and sleep disturbances, which are predictive of poor treatme

296 lating evidence indicates that circadian and sleep disturbances, which have long been considered symp

297 Core symptoms include pain, depression, and sleep disturbances with high comorbidity, suggesting alt

298 FFI is manifested by sleep disturbances with insomnia, autonomic disorders an

299 arousal, fear generalization, avoidance, and sleep disturbance, with comorbid ethanol intake, in a se

300 That sleep disturbance would be a candidate risk factor for A