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1 of early-stage East African trypanosomiasis (sleeping sickness).
2 hagas disease), and African trypanosomiasis (sleeping sickness).
3 iasis, visceral leishmaniasis, and gambiense sleeping sickness).
4  human African trypanosomiasis (HAT; African sleeping sickness).
5  compounds to treat Chagas disease and human sleeping sickness.
6 panosomal infection and protect from African sleeping sickness.
7 flagellum, is the causative agent of African sleeping sickness.
8 of such an approach for treatment of African sleeping sickness.
9 use the fatal human disease known as African sleeping sickness.
10 eneration of diamidines for the treatment of sleeping sickness.
11 lular protozoan parasite that causes African sleeping sickness.
12 and reduce the high mortality resulting from sleeping sickness.
13 thway as a drug target against African human sleeping sickness.
14 lyses trypanosomes, protecting against human sleeping sickness.
15 a brucei is the etiological agent of African sleeping sickness.
16 opment of novel therapeutics against African sleeping sickness.
17 osoma brucei, the causative agent of African sleeping sickness.
18 ODC is a proven drug target to treat African sleeping sickness.
19 volved with restocking was a risk factor for sleeping sickness.
20 ven drug target for the treatment of African sleeping sickness.
21 m Trypanosoma brucei, the causative agent of sleeping sickness.
22 hould be considered to prevent the spread of sleeping sickness.
23 osoma brucei, the causative agent of African sleeping sickness.
24 m Trypanosoma brucei, the causative agent of sleeping sickness.
25 e kinetoplastid parasite that causes African sleeping sickness.
26 Human African Trypanosomiasis, also known as sleeping sickness.
27  African trypanosomiasis, otherwise known as sleeping sickness.
28 osoma brucei is the causative agent of human sleeping sickness.
29 idin is a promising lead to treat late-stage sleeping sickness.
30 t for human African trypanosomiasis (HAT) or sleeping sickness.
31 t pathogenic trypanosomes that cause African sleeping sickness.
32 cei is an extracellular parasite that causes sleeping sickness.
33 ally explain the weight loss associated with sleeping sickness.
34 n disease called African trypanosomiasis, or sleeping sickness.
35 asite that causes the deadly disease African sleeping sickness.
36 seases, including malaria, dengue fever, and sleeping sickness.
37 ucei rhodesiense, the cause of acute African sleeping sickness.
38 n trypanosomiasis (HAT), also called African sleeping sickness.
39 panosoma brucei, the causal agent of African sleeping sickness.
40 fforts to develop new treatments for African sleeping sickness.
41 ed by the tsetse fly and that causes African sleeping sickness.
42  the future therapeutic treatment of African sleeping sickness.
43 an African trypanosomiasis (HAT), or African sleeping sickness.
44 trypanosomiasis (HAT), also known as African sleeping sickness.
45 is a parasitic protozoan that causes African sleeping sickness.
46 osoma brucei, the causative agent of African sleeping sickness.
47 isease and human African trypanosomiasis, or sleeping sickness.
48 ambiense Human African Trypanosomiasis (HAT, sleeping sickness), a disease that has often been consid
49 oma brucei is the causative agent of African sleeping sickness, a devastating disease endemic to sub-
50            Trypanosoma brucei causes African sleeping sickness, a disease for which existing chemothe
51 ing target to develop new treatments against sleeping sickness, a fatal disease caused by this protoz
52 t and Southern Africa are foci for Rhodesian sleeping sickness, a fatal zoonotic disease caused by tr
53 nicellular parasite Trypanosoma brucei cause sleeping sickness, a neglected tropical disease affectin
54  animal trypanosomiases, including Rhodesian sleeping sickness, a zoonosis associated with wilderness
55 auses human African trypanosomiasis (HAT) or sleeping sickness, accumulates in the meningeal spaces,
56 e Trypanosoma brucei, the causative agent of sleeping sickness across sub-Saharan Africa, depends on
57 rucei causes human African trypanosomiasis ("sleeping sickness") across sub-Saharan Africa and is a m
58            Chagas disease, leishmaniasis and sleeping sickness affect 20 million people worldwide and
59 , leishmaniasis, Chagas disease, and African sleeping sickness affect hundreds of millions of people
60               Human African trypanosomiasis (sleeping sickness) affects up to half a million people e
61 Human African trypanosomiasis, also known as sleeping sickness, affects the CNS at the late stage of
62 here is little hope of a vaccine for African sleeping sickness and a desperate need for modern drug t
63 cei, which is the parasite that causes human sleeping sickness and is also partially responsible for
64 oma brucei is the causative agent of African sleeping sickness and is known for its unique RNA proces
65 a promising drug target for diseases such as sleeping sickness and leishmaniasis.
66             African trypanosomes cause human sleeping sickness and livestock trypanosomiasis in sub-S
67 vities against diseases that include African sleeping sickness and malaria.
68 ors by parasitic protozoa that cause African sleeping sickness and malaria.
69 cei, the causative pathogen of human African sleeping sickness and nagana in domestic animals, myo-in
70 anosoma brucei is a protist parasite causing sleeping sickness and nagana in sub-Saharan Africa.
71 ia mexicana, the causative agents of African sleeping sickness and one form of leishmaniasis, respect
72 at includes the causative agents for African sleeping sickness and other devastating tropical and sub
73         The case-finding diseases (gambiense sleeping sickness and visceral leishmaniasis) are likely
74 ma brucei (the causative organism of African sleeping sickness) and cytotoxic effect against U937 hum
75 osoma brucei, the causative agent of African sleeping sickness, and GlcNAc-PI de-N-acetylase has prev
76 or such human pathologies as Chagas disease, sleeping sickness, and leishmaniasis.
77 ive, T. b. rhodesiense, which causes African sleeping sickness, and the non-human infective T. b. bru
78 osoma brucei, the causative agent of African sleeping sickness; and Plasmodium spp., the causative ag
79 ponsible for various human diseases, such as sleeping sickness, animal trypanosomiasis, or cutaneous
80 trends in the development of diagnostics for sleeping sickness are considered and progress towards a
81 a brucei, causative agent of the fatal human sleeping sickness, are essential for the parasite.
82 ere reported to have originated from endemic sleeping sickness areas.
83 soma brucei rhodesiense causes human African sleeping sickness because it has evolved an inhibitor of
84  APOL1 gene variants (G1/G2) protect against sleeping sickness but increase the risk of kidney diseas
85 ovide different levels of protection against sleeping sickness, but this comes with an increased risk
86 very that may undermine efforts to eliminate sleeping sickness by 2020.
87 en argued that the risk for trypanosomiasis (sleeping sickness), carried by tsetse flies in bushy env
88    We investigated the spatial clustering of sleeping sickness cases at the start of the outbreak.
89 ->G mutation, which protects against African sleeping sickness caused by Trypanosoma brucei gambiense
90                             The expansion of sleeping sickness caused by Trypanosoma brucei rhodesien
91                                Patients with sleeping sickness, caused by the parasite Trypanosoma br
92                                      African sleeping sickness, caused by the protozoan parasite Tryp
93 s a drug target for the treatment of African sleeping sickness, caused by Trypanosoma brucei.
94  is a recognized drug target against African sleeping sickness, caused by Trypanosoma brucei.
95                                              Sleeping sickness, caused by two trypanosome subspecies,
96 atids cause the neglected tropical diseases, sleeping sickness, Chagas disease and the leishmaniases.
97 evastating tropical diseases such as African sleeping sickness, Chagas' disease and leishmaniasis.
98 mania major, the causative agents of African sleeping sickness, Chagas' disease, and leishmaniasis.
99 rful approach to rational design of new anti-sleeping sickness chemotherapeutic drugs.
100 anosoma brucei, a causative agent of African Sleeping Sickness, constantly changes its dense variant
101                                              Sleeping sickness continues to be controlled by crisis m
102 Trypanosoma brucei, the parasite that causes sleeping sickness, cycles between an insect and a mammal
103 e Trypanosoma brucei, the causative agent of sleeping sickness, cycles between an insect and a mammal
104 osoma brucei, the etiologic agent of African Sleeping Sickness, deploys an RNA pol II that contains a
105 osoma brucei, the causative agent of African sleeping sickness, differs from its human host in severa
106 osoma brucei, the causative agent of African sleeping sickness, evades the host immune response by fr
107 ected from cattle in villages within the new sleeping sickness focus in Soroti District, Uganda.
108 ense imported to the market from the endemic sleeping sickness focus.
109            Trypanosoma brucei causes African sleeping sickness for which no vaccine exists and availa
110  in the Indian sub-continent (VL), gambiense sleeping sickness (gHAT), and Chagas disease and use it
111     Gambiense human African trypanosomiasis (sleeping sickness, gHAT) is a disease targeted for elimi
112 anosoma brucei, the causative agent of human sleeping sickness, has an intrinsic circadian clock that
113                                Human African sleeping sickness (HAT) is caused by the parasitic proto
114 sible for drug-resistant malaria and African sleeping sickness; however, efforts to develop their the
115  century witnessed an alarming resurgence in sleeping sickness (human African trypanosomiasis).
116   Trypanosoma brucei, the causative agent of sleeping sickness (Human African Trypanosomiasis, HAT),
117 orcement of surveillance, for the control of sleeping sickness (human African trypanosomiasis, HAT).
118   Trypanosoma brucei, the causative agent of sleeping sickness in Africa, undergoes antigenic variati
119 , a protozoan parasite responsible for human sleeping sickness in Africa.
120 thereby reducing the public-health burden of sleeping sickness in east Africa.
121 e epidemic of Trypanosoma brucei rhodesiense sleeping sickness in eastern Uganda, which began in 1998
122 oma brucei is the causative agent of African sleeping sickness in humans and contributes to the debil
123   Trypanosoma brucei, the causative agent of sleeping sickness in humans and livestock, expresses at
124 , the protozoan parasite that causes African sleeping sickness in humans and nagana in cattle.
125                   African trypanosomes cause sleeping sickness in humans and nagana in cattle.
126 cei causes African trypanosomiasis, known as sleeping sickness in humans and nagana in domestic anima
127 the diseases caused by African trypanosomes: sleeping sickness in humans and Nagana in livestock.
128 oma brucei is the causative agent of African sleeping sickness in humans and one of the causes of nag
129 ican trypanosome, Trypanosoma brucei, causes sleeping sickness in humans in sub-Saharan Africa.
130                     African trypanosomiasis, sleeping sickness in humans or nagana in animals, is a p
131 panosomes are protozoan parasites that cause sleeping sickness in humans through a tsetse fly vector.
132                   African trypanosomes cause sleeping sickness in humans, a disease that is typically
133 atidae and a lethal parasite causing African Sleeping Sickness in humans.
134 When they infect mammals, they cause African sleeping sickness in humans.
135 lated protozoan parasite that causes African sleeping sickness in humans.
136 te African trypanosomes, the agents of human sleeping sickness in sub-Saharan Africa.
137 present in all 29 samples from patients with sleeping sickness in Tororo District.
138 oms, in this study, we used a mouse model of sleeping sickness in which the acute infection was treat
139 itted trypanosomes (Trypanosoma spp.) cause "sleeping sickness' in man and have a serious impact on l
140 diseases, including African trypanosomiasis (sleeping sickness) in humans and nagana in economically
141 mbiense human African trypanosomiasis (gHAT, sleeping sickness) in the last two decades has led to a
142 ma brucei rhodesiense (agent of east African sleeping sickness), including a multidrug resistant clon
143             Human African trypanosomiasis or sleeping sickness is a deadly disease endemic in sub-Sah
144                                      African sleeping sickness is a disease caused by Trypanosoma bru
145                                              Sleeping sickness is a fatal disease caused by the proto
146 c adenosine signaling.SIGNIFICANCE STATEMENT Sleeping sickness is a fatal disease that disrupts the c
147                                      African sleeping sickness is a fatal disease that is caused by t
148 e disease away from the market suggests that sleeping sickness is becoming established in this new fo
149       Human African trypanosomiasis (HAT) or sleeping sickness is caused by two subspecies of Trypano
150 biense human African trypanosomiasis ([gHAT] sleeping sickness) is a vector-borne disease that is typ
151 mbiense human African trypanosomiasis (gHAT, sleeping sickness) is one of several neglected tropical
152 an African trypanosomiasis (HAT), or African sleeping sickness, is a fatal disease found throughout s
153 African trypanosomiasis (HAT), also known as sleeping sickness, is a major cause of mortality and mor
154      Human African trypanosomiasis (HAT), or sleeping sickness, is a major threat to human health thr
155 Human African trypanosomiasis, also known as sleeping sickness, is a neglected disease, and it contin
156            Human African trypanosomiasis, or sleeping sickness, is caused by infection with parasites
157            Human African trypanosomiasis, or sleeping sickness, is caused by the protozoan parasite T
158      Human African trypanosomiasis (HAT), or sleeping sickness, is caused by the protozoan parasite T
159            Human African trypanosomiasis, or sleeping sickness, is caused by the protozoan parasites
160 osoma brucei, the protozoan parasite causing sleeping sickness, is transmitted by a tsetse fly vector
161 osoma brucei, the causative agent of African sleeping sickness, is transmitted to its mammalian host
162 , which cause such human diseases as African sleeping sickness, leishmaniasis and Chagas disease.
163     Trypanosomatids, the etiologic agents of sleeping sickness, leishmaniasis, and Chagas' disease, c
164 Trypanosoma brucei, the etiological agent of sleeping sickness, localized its replication origins to
165  modelling on several NTDs, namely gambiense sleeping sickness, lymphatic filariasis, onchocerciasis,
166 he parasitic trypanosomes that cause African sleeping sickness, mating occurs during transmission by
167 d, our findings suggest that the symptoms of sleeping sickness may be because of alterations in homeo
168           African trypanosomes, the cause of sleeping sickness, need massive amounts of myristate to
169 orm Trypanosoma brucei, the agent of African sleeping sickness, normally requires mitochondrial gene
170                                      African sleeping sickness or human African trypanosomiasis, caus
171 copeia for human African trypanosomiasis (or sleeping sickness), orally dosed fexinidazole stands poi
172 port on a recent outbreak of T b rhodesiense sleeping sickness outside the established south-east Uga
173 ket was a highly significant risk factor for sleeping sickness (p<0.001) and that there was a signifi
174 evelopmental events in the life-cycle of the sleeping sickness parasite comprise integrated changes i
175 e-3-phosphate dehydrogenase (GAPDH) from the sleeping sickness parasite Trypanosoma brucei is a ratio
176            In the mammalian bloodstream, the sleeping sickness parasite Trypanosoma brucei is held po
177                 Trypanosomatids, such as the sleeping sickness parasite Trypanosoma brucei, contain a
178                         Here, we show in the sleeping sickness parasite Trypanosoma brucei, that FAP1
179                                       In the sleeping sickness parasite Trypanosoma brucei, the kinet
180                              Motility of the sleeping sickness parasite, Trypanosoma brucei, impacts
181  this model, we evaluated the effects of the sleeping sickness parasite, Trypanosoma brucei, on sleep
182                                          The sleeping sickness parasite, Trypanosoma brucei, uses quo
183           Although similar to T. brucei, the sleeping-sickness parasite, these trypanosomes do not cy
184                            The strategy that sleeping sickness parasites use to evade the mammalian i
185 ction of rare cell types in blood (including sleeping sickness parasites), and has the potential to e
186              Protozoan parasites such as the sleeping sickness pathogen Trypanosoma brucei adapt to d
187 me infection in both murine models and human sleeping sickness patients.
188                                              Sleeping sickness presents clinically as two distinct di
189 oma brucei is the causative agent of African sleeping sickness, putting at risk up to 50 million peop
190 osoma brucei, the causative agent of African sleeping sickness, relies on glycolysis as its sole ener
191 , such as anaplasmosis, relapsing fever, and sleeping sickness, remains untested.
192                                        Thus, sleeping sickness represents an attractive model to stud
193 sites that cause Chagas' disease and African sleeping sickness, respectively.
194                The parasites causing African sleeping sickness respond to citrate or cis-aconitate (C
195 tance against Trypanosoma that cause African sleeping sickness, resulting in positive selection of th
196 ite Trypanosoma brucei, which causes African sleeping sickness, TbISWI down-regulates RNA polymerase
197 osoma brucei (the causative agent of African sleeping sickness) the glycosylphosphatidylinositol (GPI
198 osomes, protozoan parasites that cause human sleeping sickness, the increased levels of IFN-gamma do
199 s the only example of cross-resistance among sleeping sickness therapies.
200 ons like malaria (Plasmodium falciparum) and sleeping sickness (Trypanosoma brucei) have driven genet
201  occurs in the protozoan that causes African sleeping sickness (Trypanosoma brucei), and the protein
202 agas disease (Trypanosoma cruzi) and African sleeping sickness (Trypanosoma brucei).
203 s typified by the causative agent of African sleeping sickness, Trypanosoma brucei In mitochondria of
204  energy metabolism in the causative agent of sleeping sickness, Trypanosoma brucei, with that of huma
205                                    The human sleeping-sickness trypanosome, Trypanosoma brucei rhodes
206                                          The sleeping sickness trypanosomes Trypanosoma brucei rhodes
207 de that one mechanism of resistance of human sleeping-sickness trypanosomes to human serum is decreas
208 e the causative agents of Chagas disease and sleeping sickness, two neglected tropical diseases where
209 can trypanosomes, parasites that cause human sleeping sickness, undergo a density-dependent different
210                 Trypanosomes causing African sleeping sickness use quorum-sensing (QS) to generate tr
211 cei, a eukaryotic human parasite that causes sleeping sickness, uses three elongases instead of type
212 f Trypanosoma brucei rhodesiense (Rhodesian) sleeping sickness, which is a fatal zoonotic disease tha
213 tive agent of Human African Trypanosomiasis (sleeping sickness), yet little is known about which PKs

 
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