ライフサイエンスコーパス: small interfering RNA

1 or diphenylene iodonium and a DUOX2-specific small interfering RNA.

2 een developed-antisense oligonucleotides and small interfering RNA.

3 ial cells in which ORMDL3 was inhibited with small interfering RNA.

4 with CRF(2)-overexpressing plasmid or CRF(2) small interfering RNA.

5 ith pharmacological agonists, inhibitors, or small interfering RNAs.

6 pharmacologic inhibitors or transfected with small interfering RNAs.

7 oteins were knocked down in cell lines using small interfering RNAs.

8 Transcript levels were decreased by small interfering RNAs.

9 (IkBa) was knocked down in Caco-2 cells with small interfering RNAs.

10 62) were knocked down in HCT-116 cells using small interfering RNAs.

11 -related lncRNAs and studied their link with small interfering RNAs.

12 Knockdown of IL-1alpha using small interfering RNA abolished IL-1beta-induced pro-IL-

13 G6PD inhibition and gene silencing (small interfering RNA) abolished the beneficial effects

14 enhanced the expression of ARHGEF1, while a small interfering RNA against ARHGEF1 and a RhoGEF inhib

15 e incorporation to glycogen was unaltered by small interfering RNA against DAPK3, palmitate oxidation

16 olon biopsy supernatants, histamine, PGE2, a small interfering RNA against EP2, or an agonist of F2R

17 MN-siPDL1 incorporates small interfering RNA against PD-L1 (siPDL1) conjugated

18 Treatment with EPZ5676 or DOT1L small interfering RNA also inhibited TGF-beta1 and serum

19 ts and 5-HT release were inhibited by Piezo2 small interfering RNA and antagonists (Gd(3+) and D-GsMT

20 ZO-1 small interfering RNA and cDNA transfection experiments

21 lastoma (NB), we undertook chromatin-focused small interfering RNA and chemical screens to uncover ep

22 sed molecular products such as modified RNA, small interfering RNA and RNA mimics/inhibitors for the

23 Small interfering RNA and small hairpin RNA interference

24 of Ash1l, Ezh2, Kdm5b, and Kdm6b by specific small interfering RNA and Vivo-Morpholino, as well as in

25 s of transposable element accumulation, more small interfering RNAs and DNA methylation around genes,

26 enes in a human liver cell line (HuH7) using small-interfering RNA and then measuring F7 messenger RN

27 peat (CRISPR)-Cas9 technology, gene-specific small interfering RNAs, and a newly developed luciferase

28 ibited by transfection of primary ASMCs with small interfering RNAs, and the effect on ASMC phenotype

29 ogenous IKKepsilon was downregulated using a small interfering RNA approach, SPL's anti-influenza vir

30 By using ADP-ribosylation factor 6 (ARF6) small interfering RNA, ARF6 dominant-negative mutant ARF

31 expression of these genes is ablated by p63 small interfering RNA as well.

32 Using small interfering RNA-based library screening in interfe

33 We have therefore generated a series of small-interfering-RNAs, capable of targeting four p53 ho

34 ene silencing specifically in hepatocytes by small interfering RNAs conjugated to triantennary N-acet

35 Depletion of the SIRT6 protein using small interfering RNA could not directly reactivate KSHV

36 e hypothesized that a mutant allele-specific small interfering RNA could rescue the cellular phenotyp

37 BP-1 by using specific inhibitors as well as small interfering RNA decreased TNFalpha-induced AATF ex

38 cell angiogenesis, and knockdown of VEGF by small-interfering RNA decreased endothelial cell prolife

39 ein complex -immunoprecipitation assays, and small interfering RNA dependency studies revealed that m

40 is alleviated by antioxidant administration, small interfering RNA depletion, or inhibition of OGG1 b

41 EP4 knockdown using gene-specific small interfering RNA did not affect the rapid phase of

42 Treatment of the NAT1 knockout cells with small interfering RNA directed toward HIF1-alpha mRNA in

43 CcnE1-siRNA (small interfering RNA) efficiently inhibited CcnE1 gene

44 e-expressed small RNAs, including endogenous small interfering RNAs (endo-siRNAs) and Piwi-interactin

45 elegans contains several types of endogenous small interfering RNAs (endo-siRNAs) produced by RNA-dep

46 ome-wide examination of heritable endogenous small interfering RNAs (endo-siRNAs) revealed that endo-

47 egulation of CD31 expression in monocytes by small interfering RNA enhanced FcgammaR-mediated phagocy

48 CLIP170 in C57BL/6 mice by CLIP170-specific small interfering RNA enhanced LPS-induced IL-6 and TNF-

49 ted with scrambled or protein kinase B (Akt) small interfering RNA following A2AR activation.

50 ation of desmoglein-1 and filaggrin, whereas small interfering RNA for KLK6, KLK13, and KLK14 partial

51 iosynthesis, for osteoblastogenesis, and for small interfering RNA for megalin (si-Meg) and control (

52 parison of the molecular events initiated by small interfering RNA for TPL2 (siTPL2) +/- TNFalpha in

53 Selective inhibitors and small interfering RNAs for NOX5 indicated that NOX5 cont

54 (2) reduced accumulation of phased secondary small interfering RNAs from two genomic loci; (3) altere

55 We then performed small interfering RNA gene knockdown experiments targeti

56 ctivity was altered by overexpression and by small interfering RNA gene knockdown.

57 ial responses to supplemental PEMFs, whereas small interfering RNA gene silencing of TRPM7 did not, c

58 by adeno-associated viral anti-TASK-1-siRNA (small interfering RNA) gene transfer.

59 RNA interference (RNAi) by topically applied small interfering RNA has potential applications for pla

60 , and SHP-2 down-regulation via silencing of small interfering RNA in endothelial cells enhanced neut

61 zation of miR2275 and a 24-nucleotide phased small interfering RNA in maize anther tapetal and arches

62 knockout of PKC-delta or knockdown of p62 by small interfering RNA in MCF-7 cells abrogates Vps34-dep

63 Conversely, reduction of FLT3L with small interfering RNA in MSCs abolishes the up-regulatio

64 tem for the potential use of allele-specific small interfering RNA in treating KID syndrome and other

65 om transfected plasmids or knocked down with small interfering RNAs in BE cells and analyzed by immun

66 Such PROMPTs are sources of small interfering RNAs in exosome-deficient mutants, per

67 w of the antiviral activity of virus-derived small interfering RNAs in fungi, plants, invertebrates a

68 adenovirus (both in vivo and in vitro), and small interfering RNAs (in vitro) to study its function

69 -4-binding RNA aptamer linked to a K3-siRNA (small interfering RNA) in CTLA-4(+) LSCs in vivo, which

70 Nrf2 knockdown (small interfering RNA) in cultured human hair follicles

71 In contrast, transfection of AP-2alpha small interfering RNA increased TACE promoter luciferase

72 Inhibition of G6PD with small interfering RNA induced podocyte apoptosis.

73 ed in human pulmonary endothelial cells with small interfering RNA-induced knockdown of LXA4 formyl p

74 production and depletion of PAT1 by specific small interfering RNA inhibited this process.

75 (dofetilide) in rats had similar effect, and small interfering RNA inhibition of hERG in beta and L c

76 Intraluminal delivery of thrombospondin-2 small interfering RNA inhibits the vascular response to

77 uantitative real-time PCR, Western blotting, small interfering RNA interference, and kinase inhibitor

78 articles, called carbon dots, for delivering small interfering RNA into the model plants Nicotiana be

79 In eukaryotes, RNA silencing, mediated by small interfering RNAs, is an evolutionarily widespread

80 Small interfering RNA knockdown of beta-arrestin 2 demon

81 Small interfering RNA knockdown of beta2-microglobulin r

82 Small interfering RNA knockdown of CAPN12 in three-dimen

83 Small interfering RNA knockdown of KAT2A or H3K9ac inhib

84 Chemical inhibition and small interfering RNA knockdown of NLRP3 in primary huma

85 ease; however, pharmacological inhibition or small interfering RNA knockdown of PAD2 within PAD4(-/-)

86 MP signaling pathway and was diminished upon small interfering RNA knockdown of sGCbeta1 or upon over

87 Small interfering RNA knockdown of Tim-3 increased IFN-a

88 h the inhibition of VIFs with acrylamide and small interfering RNA knockdown of vimentin significantl

89 h diethyl maleate, with and without anti-xCT small interfering RNA knockdown, in vitro uptake studies

90 monstrated by chromatin immunoprecipitation, small interfering RNA knockdown, PCR, immunolabeling, an

91 based on immunohistochemistry, and by using small interfering RNA knockdown, we illustrated that PIT

92 Isoform-specific small interfering RNA knockdowns and isoform-selective P

93 Using small interfering RNA knockdowns and peptide-blocking st

94 OL1 protein to APOL1-induced cell death with small interfering RNA knockdowns, pharmacologic inhibito

95 In vitro treatment with allele-specific small interfering RNA led to robust inhibition of the mu

96 GCs, including use of arrayed, whole-genome, small interfering RNA libraries.

97 Conversely, small interfering RNA-mediated depletion of eIF4E in hum

98 In contrast, genetic deficiency in, and small interfering RNA-mediated depletion of, coagulation

99 sted by using chromatin immunoprecipitation, small interfering RNA-mediated downregulation, and pharm

100 Small interfering RNA-mediated EHD2 silencing affected t

101 Small interfering RNA-mediated HIF2alpha knockdown in Be

102 Small interfering RNA-mediated knockdown (k/d) of eIF4E-

103 bitor of endosome-mediated recycling, and by small interfering RNA-mediated knockdown (KD) of FIP3.

104 Small interfering RNA-mediated knockdown of DUSP10 ident

105 Lastly, selective small interfering RNA-mediated knockdown of FcRn in the

106 sts compared with control treated cells, and small interfering RNA-mediated knockdown of PCSK6 in car

107 Small interfering RNA-mediated knockdown of TRIM28 strik

108 More importantly, small interfering RNA-mediated knockdown of VEGFR-1 expr

109 nked kinase or protein kinase C mu either by small interfering RNA-mediated knockdown or pharmacologi

110 down-modulated NKp30, that was prevented by small interfering RNA-mediated knockdown, suggesting a r

111 autophagosome accumulation after genetic or small interfering RNA-mediated LepR downregulation.

112 Small interfering RNA-mediated PPARalpha silencing and P

113 Specific small interfering RNA-mediated silencing highlighted tha

114 ZIP7 phosphorylation and were suppressed by small interfering RNA-mediated silencing of CK2alpha.

115 MC1568 treatment or small interfering RNA-mediated silencing of HDAC4 also s

116 Small interfering RNA-mediated silencing of parathyroid

117 Small interfering RNA-mediated silencing of SOCS1 and SO

118 ure genes, at mRNA and protein levels, after small interfering RNA-mediated silencing of YAP in Sk-He

119 Small interfering RNA-mediated TET2 knockdown (KD) incre

120 ined by cellular dielectric spectroscopy and small interfering RNA methods.

121 Natural antisense transcript-derived small interfering RNAs (nat-siRNAs) are a class of funct

122 us of amygdala and infused with either Kdm6b small interfering RNA or an antisense locked nucleic aci

123 Inhibition of CDK9 by small interfering RNA or CDK9 inhibitor functionally sup

124 experiments using concurrent treatment with small interfering RNA or inhibitor of chemokine receptor

125 that inhibition of Sirt1 deacetylase through small interfering RNA or selective inhibitor Ex527 great

126 sistent with in vivo data, IL-6 knockdown by small interfering RNA or the blockade of IL-6R signaling

127 ediated deletion or silencing of MANTIS with small interfering RNAs or GapmeRs inhibited angiogenic s

128 f specific miRNAs or proteins in cells using small interfering RNAs or genome editing.

129 guanine nucleotide exchange factor, ARNO, by small, interfering RNA or pharmacological inhibitors led

130 pon treatment with BRD4 inhibitors and c-MYC small interfering RNA (P < 0.01-0.001 for responding cel

131 So far, these two small interfering RNA pathways are considered to involve

132 nucleotides [nt]) and meiotic (24-nt) phased small interfering RNAs (phasiRNAs) and their patterns of

133 In grasses, two types of phased, small interfering RNAs (phasiRNAs) are expressed largely

134 Plant phased small interfering RNAs (phasiRNAs) contribute to robust

135 to generate diverse 24-nt phased, secondary small interfering RNAs (phasiRNAs), which are exceptiona

136 , TEs are controlled by the Piwi-interacting small interfering RNA (piRNA) pathway in gonads, while t

137 Transfection of Sirtuin-1 small interfering RNA prevented hnRNP F stimulation of F

138 airway SM tissues using short hairpin RNA or small interfering RNA prevented NM myosin II polymerizat

139 EV71 release, whereas depletion of PinX1 by small interfering RNA promoted apoptosis induced by etop

140 tocyte-specific nanoparticle-delivered AEG-1 small interfering RNA provided marked protection from HF

141 Indeed, transfection of CLL cells with Wnt5a small interfering RNA reduced Wnt5a mRNA and protein lev

142 Inhibition of Hsc70 by small interfering RNAs reduced RRV's ability to infect c

143 suppression of endogenous Ku70 expression by small interfering RNA reduces BER efficiency and leads t

144 Here, we report the development of small interfering RNA-releasing poly(amine-co-ester) nan

145 Moreover, down-regulation of AP4 by small interfering RNA resulted in a significant decrease

146 Here a genome-wide small interfering RNA screen and reporter assay were use

147 A small interfering RNA screen of 258 lipid-modifying enzy

148 VS and evades degradation, a high-throughput small interfering RNA screen targeting membrane traffick

149 We performed a small interfering RNA screen to identify targets for cut

150 We subsequently reported a whole-genome small interfering RNA screening for factors involved in

151 By combining mass spectrometry analysis with small interfering RNA screening, we identify the polarit

152 In experimental systems, depletion of G9a by small interfering RNA/short hairpin RNA or inhibition of

153 siRNA-1, a bacteria-induced plant endogenous small interfering RNA, silences the AtRAP gene, which en

154 for these KLKs in keratinocytes by targeted small interfering RNA silencing before S. aureus exposur

155 ted by inhibition of TGFBR2 kinase activity, small interfering RNA silencing of Tgfbr2 expression, or

156 d-repeat transposable element (MITE)-derived small interfering RNA (siRNA) (here referred to as siR10

157 Treatment with small interfering RNA (siRNA) against C5, which is forme

158 hages either by chemical inhibitor GW4869 or small interfering RNA (siRNA) against SMPD3 results in d

159 silencing activity of Lipoplex, a complex of small interfering RNA (siRNA) and cationic liposomes.

160 essential for HIV replication in genome-wide small interfering RNA (siRNA) and clustered regularly in

161 reactions that account for channeling in the small interfering RNA (siRNA) biogenesis phase of the Ar

162 e F1 hybrids showed that the majority of the small interfering RNA (siRNA) clusters had a higher expr

163 We demonstrated using small interfering RNA (siRNA) depletion and inhibitor st

164 dification Altriol Nucleic Acid (ANA) within small interfering RNA (siRNA) duplexes that were otherwi

165 When made with modified small interfering RNA (siRNA) duplexes, SNAs act as sing

166 Small interfering RNA (siRNA) holds inherent advantages

167 Clinical translation of therapies based on small interfering RNA (siRNA) is hampered by siRNA's com

168 Specifically, we observed that small interfering RNA (siRNA) knockdown of a mechanosens

169 3 (GSK3) performed using a Wnt inhibitor and small interfering RNA (siRNA) knockdown of critical comp

170 Small interfering RNA (siRNA) knockdown of endogenous BK

171 Moreover, small interfering RNA (siRNA) knockdown of topoisomerase

172 In addition, small interfering RNA (siRNA) knockdown studies suggeste

173 ropism in human cancer cells, we performed a small interfering RNA (siRNA) library screen targeting t

174 tumours, suggesting that its inhibition via small interfering RNA (siRNA) may be an amenable approac

175 f Raptor, the defining subunit of mTORC1, by small interfering RNA (siRNA) negatively affects ZIKV pr

176 y pathway in HL-1 cardiomyocytes with either small interfering RNA (siRNA) or Mdivi-1 caused marked r

177 or to regulate intracellular trafficking of small interfering RNA (siRNA) or microRNA (miRNA).

178 We previously demonstrated that the small interfering RNA (siRNA) pathway and siRNA from a f

179 ing RNA (piRNA) pathway in gonads, while the small interfering RNA (siRNA) pathway is dedicated to TE

180 Transfection of p44/42 MAPK or hnRNP F small interfering RNA (siRNA) prevented insulin inhibiti

181 In this study, we performed a large-scale small interfering RNA (siRNA) screen targeting host kina

182 Downregulation of ROCK1 by small interfering RNA (siRNA) selectively reduced the co

183 Small interfering RNA (siRNA) silencing of DNMT3A expres

184 re bleeding, we hypothesized that a suitable small interfering RNA (siRNA) targeting hepatic FXIII-B

185 Small interfering RNA (siRNA) targeting of E2 reversed t

186 Here, we propose using small interfering RNA (siRNA) therapeutics to directly t

187 We therefore used small interfering RNA (siRNA) to knock down the essentia

188 try was unaltered in both cells treated with small interfering RNA (siRNA) to Rab5 or Rab7 and cells

189 oride (CoCl2), 2-methoxyestradiol (2-MeOE2), small interfering RNA (siRNA) transfection and adenoviru

190 Chemical inhibitors and small interfering RNA (siRNA) were used to confirm the r

191 ed in hCAECs when ILF3 is knocked down using small interfering RNA (siRNA), but are significantly inc

192 ed lipid-polymer nanoparticles encapsulating small interfering RNA (siRNA), for the silencing of gene

193 ooth muscle cells using inhibitor screening, small interfering RNA (siRNA), immunoprecipitation (IP),

194 d in vivo assays were utilized; IRF5 or IRF4 small interfering RNA (siRNA), lentivirus, and condition

195 This process was disrupted by small interfering RNA (siRNA)-based down-regulation of a

196 In this study, small interfering RNA (siRNA)-based screening of approxi

197 Small interfering RNA (siRNA)-based therapies are provin

198 Herein, we report an small interfering RNA (siRNA)-based vesicle (siRNAsome),

199 n between fission yeast PAF1 repressing AGO1/small interfering RNA (siRNA)-directed silencing [13, 14

200 at HDAC5 decreased LSD1 protein acetylation, small interfering RNA (siRNA)-mediated HDAC5 knockdown d

201 romosome conformation data in keratinocytes, small interfering RNA (siRNA)-mediated knockdown in skin

202 Interestingly, small interfering RNA (siRNA)-mediated knockdown of GPR6

203 Importantly, small interfering RNA (siRNA)-mediated knockdown of NAP1

204 junction with pharmacologic PLK1 inhibitors, small interfering RNA (siRNA)-mediated knockdown, and ov

205 sociated, and newly synthesized mu1, we used small interfering RNA (siRNA)-mediated knockdown.

206 functions in regulating necroptosis, we used small interfering RNA (siRNA)-mediated knockdown.

207 In nsp1beta-overexpressing cells or small interfering RNA (siRNA)-mediated Nup62 knockdown c

208 Using single-guide RNA (sgRNA)/dCas9 and small interfering RNA (siRNA)-mediated protein knockdown

209 Small interfering RNA (siRNA)-mediated silencing of KLF2

210 target AXL is to silence its expression with small interfering RNA (siRNA).

211 TGF-beta was further verified using specific small interfering RNA (siRNA).

212 by 3MA or autophagy-related protein 7 (Atg7) small interfering RNA (siRNA).

213 tagonist AA92593, or after OPN4 knockdown by small interfering RNA (siRNA).

214 luminal delivery of thrombospondin-2 (TSP-2) small interfering RNA (siRNA).

215 y by suppressing allele-specific genes using small interfering RNA (siRNA).

216 he intercellular and systemic trafficking of small interfering RNA (siRNA)/microRNA (miRNA) is a cent

217 Model predictions were validated using small interfering RNA (siRNA)/short hairpin RNA (shRNA)

218 promising avenue for drug development, with small interfering RNAs (siRNA) and microRNAs gaining tra

219 kemia (AML), we performed small-molecule and small-interfering RNA (siRNA) screens of primary AML pat

220 glucan-coated particles (glucan-encapsulated small interfering RNA [siRNA] particles [GeRPs]) were al

221 2B knockdown with RNA interference for MUC4 (small interfering RNA [siRNA]-MUC4) was used to analyze

222 lexes in the nucleus, and using inhibitor or small interfering RNAs (siRNAs) against caveolin-1 or Ti

223 h as nonsteroidal anti-inflammatory drugs or small interfering RNAs (siRNAs) against COX-1 and COX-2,

224 in ectopic CHG methylation, as well as 24-nt small interfering RNAs (siRNAs) and histone H3 lysine di

225 f transgenes involves abundant 21-nucleotide small interfering RNAs (siRNAs) and low-abundance 22-nuc

226 have been identified that enhance potency of small interfering RNAs (siRNAs) and that reduce off-targ

227 Piwi-interacting RNAs (piRNAs) and small interfering RNAs (siRNAs) are distinct classes of

228 Small interfering RNAs (siRNAs) derived from RNAi-5x wer

229 -infected plants accumulate 21-24 nucleotide small interfering RNAs (siRNAs) derived from viral RNA (

230 RNAit, which can be used to design a pool of small interfering RNAs (siRNAs) for highly effective, sp

231 e proteins loaded with microRNAs (miRNAs) or small interfering RNAs (siRNAs) form the RNA-induced sil

232 ted by 21- to 22-nucleotide or 24-nucleotide small interfering RNAs (siRNAs) generated from previousl

233 f gene expression throughout the brain using small interfering RNAs (siRNAs) has not been achieved.

234 Small interfering RNAs (siRNAs) have revolutionized the

235 Delivery of therapeutic small interfering RNAs (siRNAs) in an effective dose to

236 d interplay between Global Genome Repair and small interfering RNAs (siRNAs) in the recognition of DN

237 Small interfering RNAs (siRNAs) promote RNA degradation

238 that small-molecule FEN1 inhibitors and FEN1 small interfering RNAs (siRNAs) selectively killed BRCA1

239 leles, which inhibit seed color by producing small interfering RNAs (siRNAs) targeting chalcone synth

240 of total coding space can precisely generate small interfering RNAs (siRNAs) that are active in the R

241 as previously thought, but rather secondary small interfering RNAs (siRNAs) that are produced by RNA

242 processed by DICER-LIKE3 into 24-nucleotide small interfering RNAs (siRNAs) that guide RNA-directed

243 nthesizes double-stranded RNA precursors for small interfering RNAs (siRNAs) that guide TE methylatio

244 abidopsis seed development involves maternal small interfering RNAs (siRNAs) that induce RNA-directed

245 Small interfering RNAs (siRNAs) that silence genes of in

246 In addition, we found that treatment with small interfering RNAs (siRNAs) that target DDB1 or HBx

247 on of circ-MDM2 Knocking down circ-MDM2 with small interfering RNAs (siRNAs) that targeted circ-MDM2

248 ery processes viral double-stranded RNA into small interfering RNAs (siRNAs) to suppress viral replic

249 In studies using small interfering RNAs (siRNAs), responses to AR were si

250 in vivo, it also associates with endogenous small interfering RNAs (siRNAs).

251 s tissue accumulation and cellular uptake of small interfering RNAs (siRNAs).

252 nsporting gene-modulating molecules, such as small interfering RNAs (siRNAs).

253 hey are distinct from microRNAs (miRNAs) and small interfering RNAs (siRNAs).

254 d RNAs (pUG RNAs) as templates to synthesize small interfering RNAs (siRNAs).

255 ctive tissues, especially 24-nucleotide (nt) small interfering RNAs (siRNAs).

256 ed production of a diverse pool of secondary small interfering RNAs (siRNAs).

257 NAs in plants include microRNAs (miRNAs) and small interfering RNAs (siRNAs); sRNAs are known to trav

258 Lipid-conjugated small-interfering RNAs (siRNAs) exhibit accumulation and

259 r-Cas9-mediated deletion of Mm47, as well as small interfering RNA studies in mice primary macrophage

260 cyclosporine A or knockdown of NFATc4 using small interfering RNA suppressed ET-1-induced TRPC6 up-r

261 In hASMCs, an ARHGEF1 small interfering RNA suppressed the effects of BK and T

262 RORalpha knockdown using small interfering RNAs suppressed CYP2B6 mRNAs in HPH, w

263 combinant IL-1RA, or IL-1 receptor-targeting small interfering RNA suppresses MKalpha3(+) conditioned

264 the biogenesis of TAS3-derived trans-acting small interfering RNA (ta-siRNA), which represses ARF3 e

265 ng them, microRNAs (miRNAs) and trans-acting small interfering RNAs (ta-siRNAs) mainly inhibit gene e

266 articles (LNP) loaded with a Dicer substrate small interfering RNA targeting catenin beta 1 (CTNNB1;

267 We show that a single transfection of small interfering RNA targeting class II transactivator

268 In cultured tubular cells, MAP3K14 small interfering RNA targeting decreased inflammation a

269 and Col1a1 in PTH1R-VKO VSM was inhibited by small interfering RNA targeting Mkl1 and by treatment wi

270 ajor histocompatibility complex molecules by small interfering RNA targeting of class II transactivat

271 estigate the potential of topically applying small interfering RNA targeting Pcsk9 as a psoriasis tre

272 t Toll-like receptor (TLR)1/TLR2, as well as small interfering RNA targeting TLR1/TLR2, reduced the e

273 hanced pLTF via intrathecal (C4) delivery of small interfering RNAs targeting BDNF or TrkB mRNA, and

274 on of HCV, were transfected these cells with small interfering RNAs targeting inhibitory SMADs to ana

275 Transfection of small interfering RNAs targeting YAP/TAZ blocked the mig

276 lncRNAs that produce trans-acting or phased small-interfering RNA (tasiRNA/phasiRNAs).

277 blotting, receptor binding, gene expression, small interfering RNA technology, reporter activity, and

278 Cells were transfected with small interfering RNAs that knock down PFKFB3 or CPEB4.

279 ncing by 20~23-nucleotide (nt) microRNAs and small interfering RNAs that recruit Argonaute proteins t

280 imination of an anti-viral host factor using small interfering RNA, thus obviating the need for a com

281 Using small interfering RNA to deplete a subset of phosphoryla

282 Use of small interfering RNA to knock down AW112010 expression

283 s targeting tissue factor pathway inhibitor, small interfering RNA to reduce antithrombin expression

284 h LTB receptor agonist, and transfected with small interfering RNAs to knock down RELB.

285 cyclic AMP production by control and OR10G7 small interfering RNA-transfected keratinocytes in respo

286 This response was abolished in OR10G7 small interfering RNA-transfected keratinocytes.

287 Either alpha3 or gamma1 subunit silencing by small interfering RNA transfection changed the GABA-resp

288 erative modification of endothelial cells by small interfering RNA transfection could shape the natur

289 egeneration, whereas ES treatment after FIG4-small interfering RNA transfection enhanced neural diffe

290 more susceptible to bacterial infection, and small interfering RNA treated-macrophages showed reducti

291 riatic reactions in Pcsk9-knockout and Pcsk9 small interfering RNA-treated mice, and we also used cul

292 Notably, allele-specific small interfering RNA treatment caused only low-level of

293 ressors of RNAi, many of which inhibit viral small interfering RNA (vsiRNA) production.

294 can trigger the biogenesis of virus-derived small interfering RNAs (vsiRNAs), we show that features

295 Small interfering RNA was used to decrease transcript le

296 l, a twice-yearly injection of inclisiran, a small interfering RNA, was shown to inhibit hepatic synt

297 Using small interfering RNA, well-studied age-related factors

298 Interestingly, 24-nt small interfering RNAs were enriched in the 5' and 3' fl

299 ing of infected mosquitoes showed that viral small-interfering RNAs were elevated upon ZIKVDeltaSF1 a

300 rombin (Serpinc1) and protein C (Proc) using small interfering RNA without additional triggers also r