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1 e in the levels of regulatory ncRNAs such as small nuclear and nucleolar RNAs (snRNAs and snoRNAs).
5 of lemurs employed limited mitochondrial or small nuclear data sets, with many relationships poorly
6 viduals, a few of them have been extended to small nuclear families, but none can be applied to large
7 at co-segregates with a disease phenotype in small nuclear families, from genome-wide oligonucleotide
8 ter irradiation, CENP-A is found in multiple small nuclear foci that are mutually exclusive to gammaH
9 In contrast, many unicellular organisms with small nuclear genomes seem to have lost entirely the RNA
10 sformation of European kinship, by promoting small, nuclear households, weak family ties, and residen
13 croRNAs (miRNAs), Piwi-interacting (piRNAs), small nuclear, nucleolar, cytoplasmic (sn-, sno-, scRNAs
14 ed with highly expressed histone genes and U small nuclear or nucleolar RNA (sn/snoRNA) loci that for
17 phase and causes dramatic disorganization of small nuclear ribonuclear protein and serine-arginine ri
19 ned that RBM20 interacts with both U1 and U2 small nuclear ribonucleic particles (snRNPs) and suggest
20 ibute to a better understanding of Gemin5 in small nuclear ribonucleic protein (snRNP) biogenesis as
21 he present study, we characterized U1-70-kDa small nuclear ribonucleoprotein (70-kDa) autoantigen-spe
25 scovered an RNA motif that recognizes the U1 small nuclear ribonucleoprotein (snRNP) and is essential
26 issense mutants can rescue iMEF survival and small nuclear ribonucleoprotein (snRNP) assembly, demons
33 urney to the spliceosome.The mechanism of U6 small nuclear ribonucleoprotein (snRNP) biogenesis is no
36 Interestingly, canonical CB foci and coilin/small nuclear ribonucleoprotein (snRNP) co-localization
37 eoli and bound what we believe to be a novel small nuclear ribonucleoprotein (snRNP) complex composed
38 essential gene encoding a subunit of the U5 small nuclear ribonucleoprotein (snRNP) complex of the s
39 binds 7SK RNA and, as a component of the 7SK small nuclear ribonucleoprotein (snRNP) complex, is recr
43 many splicing factors, including the key U2 small nuclear ribonucleoprotein (snRNP) component SF3B1
44 spliceostatin A, sudemycin E binds to the U2 small nuclear ribonucleoprotein (snRNP) component SF3B1.
45 7, 251, 261 and 271 residues of MoSNP1, a U1 small nuclear ribonucleoprotein (snRNP) component, likel
49 licing factor Tat-SF1 associates with the U2 small nuclear ribonucleoprotein (snRNP) of the spliceoso
50 ous nuclear ribonucleoproteins (hnRNPs), and small nuclear ribonucleoprotein (snRNP) particles throug
52 novo motif analysis shows PAS signals and U1 small nuclear ribonucleoprotein (snRNP) recognition site
54 olecular recognition of tau pre-mRNA by a U1 small nuclear ribonucleoprotein (snRNP) splicing factor.
55 nisms that regulate P-TEFb involving the 7SK small nuclear ribonucleoprotein (snRNP), factors that co
56 is inhibited by HEXIM1 or HEXIM2 in the 7SK small nuclear ribonucleoprotein (snRNP), which contains,
57 Both the BBR and BPS interact with the U2 small nuclear ribonucleoprotein (snRNP)-associated SF3b
61 he early spliceosome assembly begins with U1 small nuclear ribonucleoprotein (U1 snRNP) binding to th
62 n the disease, including U1-70K and other U1 small nuclear ribonucleoprotein (U1 snRNP) spliceosome c
63 the U1 small nuclear RNA component of the U1 small nuclear ribonucleoprotein (U1 snRNP) splicing fact
69 t is characterized by high levels of anti-U1 small nuclear ribonucleoprotein 70k autoantibodies and a
71 raised against the main MCTD autoantigen U1 small nuclear ribonucleoprotein 70k were found in nearly
72 r messenger RNAs (pre-mRNAs) contains the U7 small nuclear ribonucleoprotein and shares the key cleav
73 to understand the mechanism of SMN-assisted small nuclear ribonucleoprotein assembly and the underly
74 Here we show that GEMIN2, a spliceosomal small nuclear ribonucleoprotein assembly factor conserve
75 pICln, SMN and Gemin5, which are involved in small nuclear ribonucleoprotein assembly, have an import
77 hanced complex A formation and binding of U2 small nuclear ribonucleoprotein auxiliary factor 65 kDa
78 d splicing regulatory proteins, including u2 small nuclear ribonucleoprotein auxiliary factor 65-kDa
80 PID in the liberation of P-TEFb from the 7SK small nuclear ribonucleoprotein complex (7SK snPNP).
81 ibitor (PSI) and its interaction with the U1 small nuclear ribonucleoprotein complex (snRNP) control
82 luded diverse components of the U4/U6.U5 tri-small nuclear ribonucleoprotein complex and several spli
83 clin T1 and CDK9 are incorporated in the 7SK small nuclear ribonucleoprotein complex containing the i
85 ncode core components of the spliceosomal U6 small nuclear ribonucleoprotein complex, regulate circad
86 plicing complex Bact consisting of the three small nuclear ribonucleoprotein complexes (snRNPs) U2, U
88 ckdown of proteins associated with different small nuclear ribonucleoprotein complexes and by using t
89 tein complex with the methylosome components small nuclear ribonucleoprotein D3b (SmD3b) and protein
90 Brr2 enzyme, which is essential for U4/U6 di-small nuclear ribonucleoprotein disruption during splice
91 of PWS carrying a paternal (p) deletion from small nuclear ribonucleoprotein N (Snrpn (S)) to ubiquit
92 x, SF3B3 and SF3B5, that form part of the U2 small nuclear ribonucleoprotein particle (snRNP) are als
94 he 5' splice site, and a component of the U2 small nuclear ribonucleoprotein particle (snRNP) complex
95 k9-cyclin T modules from large, inactive 7SK small nuclear ribonucleoprotein particle (snRNP) complex
97 ) domain of spliceosomal A protein of the U1 small nuclear ribonucleoprotein particle (U1A) interacti
98 esidues 885-2413) in complex with Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor
99 hat SmD1, a core component of the Drosophila small nuclear ribonucleoprotein particle implicated in s
100 ceosome assembly within the mature U2 snRNP (small nuclear ribonucleoprotein particle), and its displ
104 r messenger RNA substrate bound to U1 and U2 small nuclear ribonucleoprotein particles (snRNPs), and
107 of Sm core structures of spliceosomal U-rich small nuclear ribonucleoprotein particles (UsnRNPs) requ
108 he U12-type spliceosomes, large complexes of small nuclear ribonucleoprotein particles and associated
109 LIP, which immunoprecipitates SmB along with small nuclear ribonucleoprotein particles and auxiliary
110 autoreactive B cells that recognize self-Ag small nuclear ribonucleoprotein particles with activated
111 important for the biogenesis of spliceosomal small nuclear ribonucleoprotein particles, but downstrea
112 d the spliceosome, which is composed of five small nuclear ribonucleoprotein particles, U1, U2, U4/U6
113 3), insulin-like growth factor 2 (IGF2), and small nuclear ribonucleoprotein polypeptide N, and the l
115 nts, FLICE-associated huge protein, Mute, U7 small nuclear ribonucleoprotein, and MPM-2 phosphoepitop
116 mic acid, which releases P-TEFb from the 7SK small nuclear ribonucleoprotein, they turned green.
117 the latter, it is incorporated into the 7SK small nuclear ribonucleoprotein, which contains hexameth
118 -COP protein co-immunoprecipitates with SMN, small nuclear ribonucleoprotein-associated assembly fact
120 nal transcribed allele of the imprinted gene Small nuclear ribonucleoprotein-associated polypeptide N
121 at sequential addition of the U4/U6 proteins small nuclear ribonucleoprotein-associated protein 1 (Sn
123 spliceosome is a complex machine composed of small nuclear ribonucleoproteins (snRNPs) and accessory
124 dynamic RNA-protein machinery consisting of small nuclear ribonucleoproteins (snRNPs) and non-snRNP
125 The prespliceosome, comprising U1 and U2 small nuclear ribonucleoproteins (snRNPs) bound to the p
126 5), which are required for the biogenesis of small nuclear ribonucleoproteins (snRNPs) involved in mR
128 sequential recruitment and rearrangement of small nuclear ribonucleoproteins (snRNPs) on a pre-mRNA
129 rected cross-linking with in vitro assembled small nuclear ribonucleoproteins (snRNPs) or spliceosome
130 lear domains important for the biogenesis of small nuclear ribonucleoproteins (snRNPs) which function
131 onents of the spliceosome, U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), contain seven
135 uclear domain important to the biogenesis of small nuclear ribonucleoproteins and telomerase, complex
136 evidence indicates that U1-70K and other U1 small nuclear ribonucleoproteins are Sarkosyl-insoluble
138 erlying the conversion of soluble nuclear U1 small nuclear ribonucleoproteins into insoluble cytoplas
139 proteins found in the U1 and U2 spliceosomal small nuclear ribonucleoproteins is highly conserved.
140 ormation of aberrant U11- and U12-containing small nuclear ribonucleoproteins that impair the efficie
141 me proteins associated with the uridine-rich small nuclear ribonucleoproteins U2, U5, and U6 and the
147 rt that LARP7, BCDIN3, and the noncoding 7SK small nuclear RNA (7SK) are vital for the formation and
152 with U1 and U2 gene loci, which produce the small nuclear RNA (snRNA) component of the respective sn
155 re highly enriched at RNA Pol II-transcribed small nuclear RNA (snRNA) genes, and the loss of LEC res
158 We probe the structure of low-abundance U12 small nuclear RNA (snRNA) in Arabidopsis thaliana and pr
161 for the endonucleolytic cleavage of primary small nuclear RNA (snRNA) transcripts within the nucleus
162 se to the catalytic Mg(2+) site in the U2/U6 small nuclear RNA (snRNA) triplex, and the 5'-phosphate
163 vivo association between coilin and rRNA, U small nuclear RNA (snRNA), and human telomerase RNA, whi
164 cleosides from the 3' end of spliceosomal U6 small nuclear RNA (snRNA), directly catalyzing terminal
165 assembled spliceosomal complex comprising U5 small nuclear RNA (snRNA), extensively base-paired U4/U6
166 all nuclear RNP (snRNP), composed of the 7SK small nuclear RNA (snRNA), MePCE, and Larp7, regulates t
167 RNAP II-transcribed cellular RNAs, including small nuclear RNA (snRNA), small nucleolar RNA (snoRNA),
168 , U-rich sequence called the Sm site in each small nuclear RNA (snRNA), to form the core domain of th
169 the survival motor neuron (SMN) protein, U2 small nuclear RNA (snRNA), U5 snRNA, and the small CB-sp
178 f noncoding RNAs, including the uridine-rich small nuclear RNA (UsnRNA) and enhancer RNA (eRNA), and
179 iation of the large inactive P-TEFb:7SK RNP (small nuclear RNA 7SK ribonucleoprotein) complex and the
180 pecially dependent on a functional U2 snRNP (small nuclear RNA [snRNA] plus associated proteins), as
181 no oligonucleotide [MO] and an engineered U7 small nuclear RNA [snRNA]) to correct this splicing defe
182 roRNA [miRNA], small nucleolar RNA [snoRNA], small nuclear RNA [snRNA], small Cajal body-specific RNA
183 mal sequence element (PSE) recognized by the small nuclear RNA activating protein complex (SNAPc).
184 C-4, the Myb-like DNA-binding subunit of the small nuclear RNA activating protein complex, binds piRN
185 ~160-nt-long RNAs, including spliceosomal U6 small nuclear RNA and a cyclic-di-AMP binding riboswitch
187 partmentalization by fluorophore-labeling U1 small nuclear RNA and observing its distribution in the
189 tein particles (snRNPs), which consist of U1 small nuclear RNA and ten proteins, recognize the 5' spl
190 pression of IRAK4-L is mediated by mutant U2 small nuclear RNA auxiliary factor 1 (U2AF1) and is asso
192 exon and a 'U1 domain' that binds to the U1 small nuclear RNA component of the U1 small nuclear ribo
194 lex SNAP(c) is required for transcription of small nuclear RNA genes and binds to a proximal sequence
197 te snoRNA, small Cajal body RNA (scaRNA) and small nuclear RNA in human and mouse cells by convention
199 sequesters the 5'ss residues involved in U1 small nuclear RNA interactions, thereby inhibiting excis
201 ibonucleoprotein (U1-snRNP) that includes U1-small nuclear RNA is a highly conserved intranuclear mol
203 inding protein La recognizes UUU-3'OH on its small nuclear RNA ligands and stabilizes them against 3'
207 th and without the association of 7SK RNA, a small nuclear RNA that is bound to approximately 50% of
209 two ncRNAs implicated in RNA processing: U1 small nuclear RNA, a component of the spliceosome, and M
210 damage to noncoding RNAs such as rRNA, tRNA, small nuclear RNA, and small nucleolar RNA is likely to
211 nucleolar RNA, natural antisense transcript, small nuclear RNA, and small RNA using published dataset
212 neuronal identity requires upregulation of a small nuclear RNA, RN7SK, which induces accessibilities
213 tes' most abundant non-coding (spliceosomal) small nuclear RNA, silences proximal PASs and its inhibi
215 te the suppression of 3' end formation by U1 small nuclear RNA, which is known to bind pre-mRNA at th
218 n a unique transcription factor known as the small nuclear RNA-activating protein complex (SNAPc).
220 A, TFIIB, and TFIIH which, together with the small nuclear RNA-activating protein complex, form a tra
221 The Brr2 RNA helicase disrupts the U4/U6 di-small nuclear RNA-protein complex (di-snRNP) during spli
225 l of motor neuron (SMN) complex delivers pre-small nuclear RNAs (pre-snRNAs) to the heptameric Sm rin
228 , conditional production of 3'-extensions of small nuclear RNAs (snRNAs) and biogenesis of novel tran
232 ng genes requiring RNAPII for transcription, small nuclear RNAs (snRNAs) display a further requiremen
233 otspot mutations (r.3A>G) of U1 spliceosomal small nuclear RNAs (snRNAs) in about 50% of Sonic hedgeh
234 risingly, we found that TOE1 associated with small nuclear RNAs (snRNAs) incompletely processed splic
236 Cross-links identified in the U4 and U6 small nuclear RNAs (snRNAs) suggest U4/U6 stem I as a Br
237 lass of ubiquitously expressed, uridine-rich small nuclear RNAs (snRNAs) transcribed by RNA polymeras
240 natching of numerous host RNAs, particularly small nuclear RNAs (snRNAs), and avoidance of host trans
242 the cytoplasm, precursors to specific tRNAs, small nuclear RNAs (snRNAs), and small nucleolar RNAs (s
243 ell-established role in 3' end processing of small nuclear RNAs (snRNAs), attenuates MtnA transcripti
244 mitations, we previously proposed the use of small nuclear RNAs (snRNAs), especially U7snRNA to shutt
245 As (miRNAs), small nucleolar RNAs (snoRNAs), small nuclear RNAs (snRNAs), piwi-associated RNAs (piRNA
248 e assembly of heptameric Sm protein rings on small nuclear RNAs (snRNAs), which are essential for snR
249 of pseudouridines (Psis) on the spliceosomal small nuclear RNAs (snRNAs), which may enable growth at
250 es (CBs)-subnuclear compartments enriched in small nuclear RNAs (snRNAs)-and promotes efficient splic
256 ent within snatched fragments and found that small nuclear RNAs and small nucleolar RNAs contributed
257 results in the misexpression of a variety of small nuclear RNAs and small nucleolar RNAs, an effect t
262 for catalysis by unwinding base-paired U4/U6 small nuclear RNAs, a step that must be precisely timed.
263 an intricate network formed by U5, U2 and U6 small nuclear RNAs, and a pre-messenger-RNA substrate.
264 particular spliceosome components, including small nuclear RNAs, cause reproducible uniquely distribu
265 uide chemical modifications of ribosomal and small nuclear RNAs, functions that are carried out in th
266 show that a base-paired complex of U6 and U2 small nuclear RNAs, in the absence of the approximately
268 ed abundant small, noncoding RNAs, including small nuclear RNAs, small nucleolar RNAs (snoRNAs), cryp
275 increases the levels of spliceosomal and U7 small-nuclear RNAs and corrects RNA processing defects i
276 FLASH (Flice-associated huge protein) and U7 small nuclear RNP (snRNP) are HLB components that partic
277 ufficient for trans-splicing, which binds U1 small nuclear RNP (snRNP) through strong base-pairing wi
279 ine methyltransferase, methylates Snp1, a U1 small nuclear RNP (snRNP)-specific protein, and that the
280 mice were immunized with 50 mug of U1-70-kd small nuclear RNP fusion protein and 50 mug of U1 RNA ad
281 9-1 associates with the core component of U1 small nuclear RNP in P. patens Genome-wide analyses demo
282 ion, in which the D, E, F, and G proteins of small nuclear RNPs (snRNP) but without other components
283 autoantibody ICs containing apoptotic cells, small nuclear RNPs (snRNPs), or DNA, or directly with TL
287 or the biogenesis of ribosomes, spliceosomal small nuclear RNPs, microRNAs and the telomerase RNP.
288 ore show that mediator is a basal factor for small nuclear SL RNA gene transcription in trypanosomes
289 RNA--protein complexes (RNPs), spliceosomal small nuclear (sn), and small CB-specific (sca)RNPs.
291 A pseudouridine-modified region of the U2 small nuclear (sn)RNA anneals with the intronic branchpo
292 ereas transcription of small nucleolar (sno)/small nuclear (sn)RNA genes is terminated by the RNA-bin
297 denylase TOE1 in distinguishing the fates of small nuclear (sn)RNAs of the spliceosome from unstable
300 phomas in non-natural hosts, expresses seven small nuclear uracil-rich non-coding RNAs (called HSURs)