ライフサイエンスコーパス: so many

1 eventing a disease that touches the lives of so many.

2 xoribonucleases, raising the question of why so many activities are present in the complex.

3 cataracts are also relatively easy to treat, so many adults with impaired vision caused by cataract c

4 le reason why a single drug is indicated for so many age-related diseases is that it inhibits the agi

5 With so many agents available for the treatment of indolent l

6 H) are distinct, but converge when there are so many alleles that traits fluctuate close to their exp

7 f the tendency of this disease to present in so many and diverse patterns.

8 ed activated in a number of cancers in which so many antagonists are surrounded.

9 le explanation as to why plants have evolved so many anthocyanin repressors.

10 osmolarity, but we lack explanations for why so many antiporters are needed and for the value added b

11 notypes persist after they arise, and why do so many aposematic species exhibit intrapopulation signa

12 , these theories largely fail to explain why so many apparently distinct cognitive activities implica

13 Furthermore, the availability of so many approved treatments raises questions about the e

14 tanding of how most of them function and why so many are required.

15 However, as in so many areas of molecular biology, the advent of archae

16 chemical science and for its applications in so many aspects of everyday life.

17 ht on the mechanisms that have given rise to so many bacterial and viral ORFans.

18 Being the first woman to break through so many barriers in a totally male-dominated science mak

19 effects, questions remain, particularly why so many birds in North America do not occupy climaticall

20 nly a short period during the lytic cascade, so many cells with HHV-8 in the lytic phase responded to

21 However, little is known about how so many cellular clocks within and across brain circuits

22 Even so, many challenges relating to the implementation of ex

23 er before have cardiologists been faced with so many choices of stent, each with its own unique desig

24 The fact that so many clearing protocols exist suggests there is no on

25 st a possible structural explanation for how so many commonly used medications block HERG but not oth

26 ups of items and working-memory capacity for so many computed centroids.

27 actors are channel capacity for representing so many concurrently presented groups of items and worki

28 Why do brains have so many connections?

29 known about why insulin resistance occurs in so many contexts.

30 ediate states and accounts for why there are so many controversies about intermediates versus compact

31 ding its role in cell biology: why are there so many copies of Ter, why are they distributed over suc

32 amily evolution and clues about the need for so many CPR genes.

33 Current mapping algorithms cannot handle so many data without building hierarchies of framework m

34 rmogenesis in brown fat has been studied for so many decades that one would think there is nothing le

35 The role of ethylene in so many deficiencies suggests that, to confer specificit

36 concerned citizens seeking to understand why so many democracies are eroding and how to stop this pro

37 That SB co-occurs with so many diagnoses reinforces the need to assess current

38 How does auxin affect so many different aspects of plant growth and developmen

39 gs that identify a single reliable change in so many different cancers.

40 h identical DNA sequences differentiate into so many different cell types.

41 intermingling of corticospinal outputs from so many different cortical regions must represent an org

42 consistency between mass balance results on so many different days and in two different seasons, ena

43 nations of transcription factors can silence so many different donor programs.

44 g question of how a single gene can manifest so many different effects.

45 for the ability of HNP-1 to HNP-3 to inhibit so many different exotoxins is proposed.

46 taxias suggest a rational hypothesis for how so many different genes lead to predominantly cerebellar

47 However, there are so many different hydrogen bonding patterns that a descr

48 tly been incriminated, and it is unclear how so many different infections may play a role.

49 pective, I explain why quantum chemistry has so many different methods and why researchers should und

50 ions, how the activation and localization of so many different molecules are spatiotemporally orchest

51 The fact that APC is an integral part of so many different pathways makes it an ideal target for

52 The fact that so many different primary transforming events give rise

53 this small domain play such a large role for so many different proteins?

54 training regimen may induce improvements in so many different skills is notable because the majority

55 logy, but also raises the question as to why so many different solutions to the same biosynthetic pro

56 l surface receptors which allow infection of so many different species and cell types are still incom

57 s, and that the BAM catalyst is able to fold so many different substrates because it addresses these

58 y explain why trait exaggeration has evolved so many different times in the context of sexual selecti

59 eries of neuroscience is why neurons express so many different types of ion channels with such wide-r

60 tools that helped the discipline develop in so many different ways began to appear in the late thirt

61 oubled by a technology that causes Europeans so many difficulties?

62 ever, exactly how LRP1 functions to regulate so many distinct and specific processes is still not ful

63 volve high affinity, selective receptors for so many distinct chemical structures.

64 asts, chemoreceptors), but perhaps none show so many distinct patterns in terms of number and localiz

65 n a single lipid in a fluid bilayer regulate so many distinct physiological processes?

66 The concordance of this defect among so many diverse autoimmune-prone strains suggests that t

67 ils, as well as a kinetic explanation of why so many diverse distrust movements are now emerging acro

68 our knowledge, this is the first case where so many diverse morphologic forms were manifested in a s

69 Because PP2A is involved in so many diverse processes, it is highly regulated by bot

70 roblem of how a master regulator can control so many diverse receptors.

71 the reasons that might justify the need for so many DNA polymerases, describe their function and mod

72 itration of any soluble reductants involving so many electrons.

73 pain mechanisms within and between patients, so many experts consider pain classification as a contin

74 It is not clear why so many extracellular domains need to be evolved through

75 Thus, unlike so many facets of modern cardiovascular practice and CAD

76 nally progressed beyond phase 2 trials after so many failures on other targets.

77 ILC1s are developmentally distinct but share so many features that they are difficult to distinguish,

78 r amine groups are able to be derivatized by so many fluorogenic reagents.

79 fundamental process and has been studied by so many for so long that skeptics might ask what more th

80 However, the question remains why so many functional domains cluster together in one relat

81 How this single motor protein performs so many functions has remained a major outstanding quest

82 hy nature endowed this specific protein with so many functions may remain a mystery.

83 n important issue in parametric modeling for so many gene expression levels is the control of the num

84 onent, not least of which is why plants have so many genes for the cellulose synthase catalytic subun

85 es, raises the question of why bacteria need so many GGDEF enzymes.

86 The presence of so many highly related signaling proteins in individual

87 ilure to focus efforts on the IFIs that kill so many HIV patients has led to fundamental flaws in the

88 Here, we analyze why so many HIV-1 vaccines have failed, summarize the outcom

89 bsence of reported males, why bdelloids have so many horizontally acquired genes, and how their remar

90 How it avoids innate immune defenses in so many hosts is not understood.

91 ndard Rapid Response Team activation and did so many hours in advance.

92 or safe water or clean cooking are unused by so many households that could benefit from them.

93 The two chlorine dioxide treatments each had so many HPC counts of 0 that a meaningful statistical di

94 o predict how a law of such complexity, with so many human variables, will work out in the end.

95 one reason for the conservation of Ile51 in so many Ig VH.

96 euroscientists because it is associated with so many important cognitive functions.

97 Over the past two decades or so, many improved catalysts have been introduced, allowi

98 r terrestrial genus of animals has sponsored so many independent aquatic invasions, and no other inse

99 w to appropriately care for, and respond to, so many individuals and families coping with the exigenc

100 Because so many individuals die from starvation, disease and pre

101 t, natal dispersal is limited and sex-biased so many individuals, especially males, recruit as breede

102 We are grateful to have received so many insightful commentaries from interested colleagu

103 With so many interesting papers presented, it is impossible t

104 se I did not expect that varphi29 would give so many interesting results, but I worked hard, with a l

105 hat recognize zebrafish proteins are sparse, so many investigators use transgenic, lymphocyte-specifi

106 is finding provides an explanation as to why so many large proteins, without a signal peptide sequenc

107 The late Pleistocene extinction of so many large-bodied vertebrates has been variously attr

108 The observation of so many long-range interactions in a small, rigid system

109 rt period variability values between groups, so many LSI patients could be incorrectly classified as

110 In this review, we show that having so many materials allows us to use big-data methods as a

111 How and why so many materials choose dramatic non-crystallographic d

112 The fact that we have so many materials opens many exciting avenues but also c

113 ght to understand why gestating parents have so many mates and such high incidences of successful mul

114 f gain control, but we do not understand why so many mechanisms are needed or how they interact.

115 ental variables that follow a random walk or so many mechanisms were affecting these variables, in di

116 Even so, many medical school-based radiology departments have

117 Even so, many members of the public currently underestimate t

118 in phospholipid structure and why there are so many membrane lipids.

119 oduce syndromes like bipolar disorder or why so many mental illnesses co-occur together.

120 level of EGFR expression is investigated by so many methods in a liquid and solid biopsy.

121 Actually, during the last two decades or so, many methods in this regard have been established in

122 microbial recovery yet the real reasons why so many microbes do not grow on artificial media remain

123 e in transendothelial migration and asks why so many molecules seem to be involved.

124 It is unclear why there are so many more neurons in sensory cortex than in the senso

125 out the same number of genes as mice and not so many more than worm, what makes us more complex?

126 to origins, providing an explanation for why so many mutants in DNA replication show checkpoint defec

127 career path are seen as being outweighed by so many negative factors, as to prompt the question, "Is

128 nature of this network helps to explain why so many neurological conditions produce dysphagia.

129 concept and spatial representations and why so many neurons are needed for robust performance at the

130 pled receptors will lead to the discovery of so many new neuropeptides that it may well double their

131 Over the past decade, so many new optical biometers, formulas, and methods (wh

132 The finding of so many new plant viruses that do not cause any obvious

133 have improved survival for premature babies, so many now present as adolescents and adults to compreh

134 ural vegetation soils, it is surprising that so many of the key components of a soil community develo

135 e two routes to exaggeration and suggest why so many of the most exaggerated insect structures scale

136 auto-catalytic and cross-catalytic nature of so many of the putative processes associated with self-r

137 Our extraordinary ability to retrieve so many of them at a later time is due in no small part

138 cterizing RXLR-EER effectors and discuss why so many of these rapidly evolving proteins are encoded b

139 of free integrins on the cell surface since so many of these receptors are bound to the surface liga

140 Even more importantly, there are so many open, exciting questions to ask.

141 m may explain why they are still retained in so many organisms.

142 diseases is its ability to infect and affect so many other family members, not just the child.

143 m nuclear physics, analytical chemistry, and so many other fields, all in one document.

144 laser that is not specific to the molecule, so many other molecular ions, including polyatomic speci

145 man and environmental health for which, like so many other small molecules, no suitable biorecognitio

146 transport of tubulin has eluded detection in so many other studies.

147 My path, like those of so many others, had too many idiosyncratic twists and tu

148 ing the 1950s, and his influence on me-as on so many others-has persisted ever since.

149 termed 2-oxoglutarate) as a co-substrate in so many oxidation reactions throughout much of nature is

150 How a single type of lipid regulates so many parallel processes is unclear.

151 Most importantly, because so many parents are unaware of the potential risk of ina

152 hat we call "the macrophage paradox:" why do so many pathogenic bacteria replicate in the very cells

153 question of why vitamin A deficiency causes so many pathologies that are independent of retinoic aci

154 eir ability to diagnose stent complications, so many patients require chest computed tomography (CT)

155 A question is why, with so many people consuming contaminated raw oysters, the i

156 The fact that so many people currently underestimate how conservative

157 With so many people infected, the overall number of neurologi

158 able, we need to consider the paradox of why so many people of color are dying from the disease yet c

159 But so many people, especially younger scientists, want to k

160 rget activation and modulation nor involving so many peptides that combinatorial explosion can occur.

161 it would not be possible to sustain herds if so many pocket Bibles were produced from fetal skins, ar

162 Even with so many possibilities for the use of carnauba wax in foo

163 Biological networks have so many possible states that exhaustive sampling is impo

164 Never before have so many potential targets been studied.

165 Why so many precursor types are needed to produce neurons ha

166 Because of the importance of tarsiers in so many primatological problems, there has been particul

167 iding translational research is fraught with so many problems that the validity of research conclusio

168 So why is the m6A writer complex composed of so many proteins?

169 of a cilium could be one of the reasons why so many receptors are located on cilia.

170 Why does calcium have so many regulatory functions?

171 t increase in politicians' willingness to do so, many remain hesitant.

172 With so many research groups generating their own data, the a

173 A broader goal is to illustrate why so many researchers are enthusiastic about the SEM appro

174 ible for the oceanic anoxia that has puzzled so many researchers for so many years.

175 As so many sepsis survivors succumb later to persistent, re

176 nalities of a replicase complex in producing so many sgRNAs, we examined initiating nucleotides of th

177 cations for how such a tiny protein can send so many signals.

178 The discrepancies between so many simulations and subsequent experimental testing

179 sources and to dominate them may explain how so many species apparently dependent on similar resource

180 some groups of organisms, like beetles, have so many species, and others, like the tuataras, so few?

181 his apparently ubiquitous system to initiate so many specific and appropriate end responses.

182 I am grateful to have received so many stimulating commentaries from interested colleag

183 seful in disease association studies because so many STR elements manifest multiallelic polymorphism.

184 It is unclear why so many structurally diverse compounds block HERG channe

185 osed motion of IgE-Fc(3-4) was possible with so many structures, and the new structures allow a more

186 size 2-5(A), the reason for the existence of so many synthetase isozymes is unclear.

187 Because cI is used in so many synthetic biology projects, the new set of varia

188 With so many therapeutic options in sight and the ongoing elu

189 hington's medical history has been recounted so many times and with such consistency that it seems th

190 Why are there so many transmitters?

191 Ecology cannot yet fully explain why so many tree species coexist in natural communities such

192 undation for the cognitive modeling embodies so many underlying implications that the subject is far

193 are more computationally costly and may have so many unknown parameters that their results are not as

194 sons provided clues toward understanding how so many variants of these multigenic loci could have evo

195 elucidate how bats serve as a reservoir for so many viruses.

196 f synapses organically permeate the brain in so many ways as a good practice of its intrinsic physiol

197 Why do cells have so many ways to die?

198 However, why bacteria carry so many weapons, and why they are so often used, remains

199 lable for both these common cancers, yet for so many women access to these is beyond reach.

200 ntion and provision of surgical treatment to so many women will need coordinated efforts, planning, a

201 One might wonder after so many years of detailed poking at such a seemingly sim

202 xia that has puzzled so many researchers for so many years.

203 r biological functions, have been hidden for so many years.

204 ains 13 ZFs, but it is unknown why Miz-1 has so many ZFs and whether they recognize and bind DNA sequ