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1 future studies of doxorubicin in metastatic soft tissue sarcoma.
2 ved no prior systemic therapy for metastatic soft tissue sarcoma.
3 our institution for a surgical procedure for soft tissue sarcoma.
4 nes, as well as in tumors from patients with soft tissue sarcoma.
5 s trabectedin exhibited efficacy in advanced soft tissue sarcoma.
6 ry subunit of PP2A, is associated with human soft tissue sarcoma.
7 ination in children and adults with advanced soft tissue sarcoma.
8 el have activity in patients with metastatic soft tissue sarcoma.
9 ogenesis, we have generated a mouse model of soft tissue sarcoma.
10 epithelial cancer, but not in this model of soft tissue sarcoma.
11 eatment of choice for patients with advanced soft tissue sarcoma.
12 utrophils in an autochthonous mouse model of soft tissue sarcoma.
13 Liposarcoma is the most common soft tissue sarcoma.
14 ochthonous mouse model of Kras(G12D) -driven soft tissue sarcoma.
15 ositive association between this variant and soft tissue sarcoma.
16 n effective treatment strategy for childhood soft tissue sarcoma.
17 18 (41%) had bone sarcoma, and 26 (59%) had soft tissue sarcoma.
18 nerve sheath tumor (MPNST) is an aggressive soft tissue sarcoma.
19 nostic performance in detection of recurrent soft-tissue sarcoma.
20 esting a potential shift in the treatment of soft-tissue sarcoma.
21 lin could be a treatment option for advanced soft-tissue sarcoma.
22 bility of eribulin in advanced or metastatic soft-tissue sarcoma.
23 rcoma metastasis in a primary mouse model of soft-tissue sarcoma.
24 icin in patients with advanced or metastatic soft-tissue sarcoma.
25 llows reliable and accurate local staging of soft-tissue sarcoma.
26 newly diagnosed lymphoma, neuroblastoma, or soft-tissue sarcoma.
27 n profiles in 608 tumours across subtypes of soft-tissue sarcoma.
28 treatment option for patients with advanced soft-tissue sarcoma.
29 coma of the liver, or unclassified malignant soft-tissue sarcoma.
30 bdomyosarcoma, a highly aggressive pediatric soft-tissue sarcoma.
31 treatment in patients with locally advanced soft-tissue sarcoma.
32 treatment for locally advanced or metastatic soft-tissue sarcoma.
33 arcoma (RMS) is the most prevalent pediatric soft-tissue sarcoma.
34 ne treatment for most patients with advanced soft-tissue sarcoma.
35 st-line treatment for advanced or metastatic soft-tissue sarcoma.
36 peripheral nerve sheath tumor, an aggressive soft-tissue sarcoma.
37 ary thyroid carcinoma, and 13% for secondary soft-tissue sarcoma.
38 on and metastasis of many cancers, including soft tissue sarcomas.
39 amous cell carcinomas, mast cell tumors, and soft tissue sarcomas.
40 inical trial involving localized, high-risk, soft tissue sarcomas.
41 tromal tumors (GISTs) are rare but treatable soft tissue sarcomas.
42 apy on survival has been minimal in advanced soft tissue sarcomas.
43 nd may be confused with nonmyogenic, non-RMS soft tissue sarcomas.
44 remains the standard treatment for advanced soft tissue sarcomas.
45 ive chemotherapy for patients with localized soft tissue sarcomas.
46 in tumorigenesis and may aid in diagnosis of soft tissue sarcomas.
47 or types including testicular carcinomas and soft tissue sarcomas.
48 man sarcoma cell lines derived from bone and soft tissue sarcomas.
49 neuroblastoma, Wilms' tumours, and bone and soft tissue sarcomas.
50 trated to be more active compared with other soft tissue sarcomas.
51 S FDA approved for the treatment of advanced soft tissue sarcomas.
52 curative for primary nonmetastatic extremity soft tissue sarcomas.
53 sarcoma (UPS) are highly genetically complex soft tissue sarcomas.
54 maging for determining treatment response in soft-tissue sarcomas.
55 l proliferation/tumorigenesis in a subset of soft-tissue sarcomas.
56 ant fatty tumors, are the second most common soft-tissue sarcomas.
57 ebo plus cisplatin in patients with advanced soft-tissue sarcomas.
58 ment of tumour vascular-disrupting drugs for soft-tissue sarcomas.
59 val in patients after resection of high-risk soft-tissue sarcomas.
60 efit in T-staging of primary bone tumors and soft-tissue sarcomas.
61 ated efficacy in nonleiomyosarcoma histology soft-tissue sarcomas.
62 might improve the treatment and prognosis of soft-tissue sarcomas.
63 topathologic tumor response in patients with soft-tissue sarcomas.
64 factor fusions (TFFs) are present in ~30% of soft-tissue sarcomas.
65 peripheral-nerve tumours, skin cancers, and soft-tissue sarcomas.
66 xorubicin as first-line therapy for advanced soft-tissue sarcomas.
67 ty patients with locally advanced high-grade soft-tissue sarcoma (10 men and 10 women; mean age, 49 +
70 homa (hazard ratio [95% CI], 3.5 [1.7-7.1]); soft-tissue sarcoma (2.8 [2.1-3.9]); breast carcinoma (2
71 ere Ewing sarcoma family tumors (54%), other soft tissue sarcomas (21%), osteosarcoma (11%), rhabdomy
72 7), breast cancer (4.6; 95% CI, 3.5 to 6.0), soft-tissue sarcoma (3.4; 95% CI, 1.9 to 5.7), thyroid c
73 ostoperative surveillance after resection of soft-tissue sarcoma (35 with high-grade sarcoma) were st
74 geted therapies currently in development for soft tissue sarcomas, a better understanding of the mole
75 tients with chemotherapy-refractory bone and soft-tissue sarcomas according to IGF-1R expression by i
76 It represents the most frequent malignant soft tissue sarcoma affecting the pediatric population a
77 olar rhabdomyosarcomas (ARMS) are aggressive soft-tissue sarcomas affecting children and young adults
79 nced, unresectable, or metastatic high-grade soft-tissue sarcoma, age 18-60 years with a WHO performa
80 rationalizes clinical studies in humans with soft tissue sarcoma, an indication with a notably high u
81 ents aged 18 years and older with metastatic soft-tissue sarcomas, an Eastern Cooperative Oncology Gr
82 orrelated with clinical outcomes in Ewing's, soft tissue sarcomas and gastrointestinal stromal tumor.
83 [standard deviation], 45 men) with recurrent soft-tissue sarcoma and 63 age-, sex-, and tumor-matched
84 rapy is beneficial in pre-clinical models of soft-tissue sarcoma and deserves further exploration in
86 tandard of care for patients with metastatic soft-tissue sarcoma and median overall survival for thos
88 nscriptomic marker that identifies high-risk soft-tissue sarcomas and is associated with high metasta
89 ocally advanced, unresectable, or metastatic soft-tissue sarcomas and so this combination cannot be r
91 on-Hodgkin lymphoma, acute myeloid leukemia, soft-tissue sarcoma, and central nervous system cancer.
92 onfirms the immune subtypes in patients with soft-tissue sarcoma, and unravels the potential of B-cel
93 fficient details to encompass the variety of soft-tissue sarcomas, and available prognostic methods n
94 a, CNS tumours, neuroblastoma, Wilms tumour, soft-tissue sarcomas, and bone cancer) by comparing both
95 en in advanced uterine leiomyosarcoma, other soft-tissue sarcomas, and pediatric sarcomas is discusse
96 tcomes for children and adults with advanced soft tissue sarcoma are poor with traditional therapy.
98 ing the preoperative management of extremity soft tissue sarcomas are continuing in an attempt to opt
101 in patients with unresectable or metastatic soft-tissue sarcoma at 16 clinical sites in the USA.
102 croscopically resected, Trojani grade II-III soft-tissue sarcomas at any site, no metastases, perform
103 ative incidence for all SCs combined and for soft tissue sarcomas, bone cancers, and melanoma were ca
104 Liposarcomas are the most common type of soft tissue sarcoma but their genetics are poorly define
105 nse to preoperative treatment in adults with soft-tissue sarcoma can be achieved in only a few patien
107 ubsets with different outcomes, allowing the Soft Tissue Sarcoma Committee of the Children's Oncology
108 improves survival of patients with advanced soft-tissue sarcoma compared with doxorubicin alone.
111 ard to the management of these patients with soft tissue sarcomas: delays in diagnosis, trial availab
112 habdomyosarcoma, synovial sarcoma, and adult soft tissue sarcomas diagnosed in adolescents and young
114 ancer, and in a mouse model of autochthonous soft-tissue sarcoma driven by a G12D mutation in KRAS an
115 therapeutic options are needed for bone and soft tissue sarcomas, especially for patients with metas
116 Angiosarcoma (AS) is a rare understudied soft tissue sarcoma exhibiting endothelial cell differen
117 and ifosfamide-which have been used to treat soft-tissue sarcoma for more than 30 years-still have an
119 Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma found in children and young adults.
120 gradual migration in the local treatment of soft tissue sarcomas from amputation and similar radical
122 17 of 54 patients in the IGF-1R-positive soft-tissue sarcoma group (31%; one-sided 95% CI lower b
124 e additional patients in the IGF-1R-positive soft-tissue sarcoma group (total of 57 patients) and nin
125 the bone sarcoma group and four [10%] in the soft-tissue sarcoma group) had treatment-emergent seriou
126 e of three treatment groups: IGF-1R-positive soft-tissue sarcoma (group A), IGF-1R-positive bone sarc
132 omyosarcoma (RMS), the most common pediatric soft-tissue sarcoma, has two major histological subtypes
133 osensitive tumors compared to other types of soft tissue sarcomas, however, prognosis for advanced re
134 erexpression of MMP-1 and MMP-8 in the human soft tissue sarcoma HSTS26T leads to a significant deple
135 (LMS) is one of the most common subtypes of soft tissue sarcoma in adults and can occur in almost an
136 S/DDLS) account for approximately 13% of all soft tissue sarcoma in adults and cause substantial morb
137 Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and represents a high-gr
138 Rhabdomyosarcoma (RMS) is the most frequent soft tissue sarcoma in children that shares many feature
143 Rhabdomyosarcoma (RMS) is the commonest soft-tissue sarcoma in childhood and is characterized by
145 habdomyosarcomas (RMS) are the most frequent soft-tissue sarcoma in children and characteristically s
149 therapy options for patients with metastatic soft-tissue sarcomas in the United States, after a gap o
150 I, 2.3% to 4.8%), whereas body and extremity soft-tissue sarcoma incidence was rare until age 30, whe
151 also highly unstable in three of eight ALT+ soft tissue sarcomas, indicating that somatic destabiliz
152 oblastomas (IRR = 2.34, 95% CI: 1.21, 4.16), soft-tissue sarcomas (IRR = 2.12, 95% CI: 1.09, 3.79), a
159 for adolescent and young adult patients with soft tissue sarcomas lag behind those of children diagno
160 on (R0, R1) of abdominal and retroperitoneal soft-tissue sarcomas (median diameter 10 cm, G2 48.3%, G
162 b with doxorubicin in patients with advanced soft-tissue sarcoma met its predefined primary endpoint
164 ee, and overall survival among patients with soft-tissue sarcoma, most of whom had received at least
165 diagnosis of locally advanced or metastatic soft-tissue sarcoma not previously treated with an anthr
166 t outcome in paediatric non-rhabdomyosarcoma soft-tissue sarcoma (NRSTS), but no risk stratification
167 e conducted analyses separately for bone and soft-tissue sarcomas occurring in the head and neck (in/
170 omyosarcoma (ARMS) is one of the most common soft tissue sarcoma of childhood, yet the outcome for th
172 Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of skeletal muscle origin in childre
173 chymally transformed breast cancer cells and soft tissue sarcomas of diverse histological subtypes.
174 Guided Preoperative Radiotherapy for Primary Soft Tissue Sarcomas of the Extremity) study are appropr
177 ults (aged >=18 years) with locally advanced soft-tissue sarcoma of the extremity or trunk wall, of a
178 produce excellent results, such as bone and soft-tissue sarcoma of the skull base, head and neck, an
179 lly confirmed locally advanced or metastatic soft-tissue sarcoma of Trojani grade 2 or 3, disease pro
181 is of an advanced unresectable or metastatic soft-tissue sarcoma, of intermediate or high grade, for
182 t among survivors of CNS tumors and bone and soft tissue sarcomas on strength testing (score +/- SD:
183 el, phase 2 study, we enrolled patients with soft-tissue sarcoma or bone sarcoma from 12 academic cen
185 hese three groups contained either recurrent soft-tissue sarcomas or positive postoperative findings
186 dgkin lymphoma, kidney tumor, neuroblastoma, soft-tissue sarcoma, or malignant bone tumor before the
187 ; colorectal; non-Hodgkin lymphoma; thyroid; soft-tissue sarcoma; ovarian; bladder; other female geni
188 ially increased risks of subsequent bone and soft-tissue sarcomas, particularly after radiotherapy.
189 a defective p53 response, we found that male soft tissue sarcoma patients carrying the minor T allele
191 vide modest benefit overall to nonadipocytic soft tissue sarcoma patients, but we have yet to identif
192 We present data from a pilot study in 10 soft-tissue sarcoma patients imaged with (11)C-thymidine
194 e of histologic type in radiation-associated soft tissue sarcomas (RASs) and determine whether RASs a
195 total of 53 patients with advanced non-GIST soft tissue sarcomas received sunitinib 37.5 mg daily.
196 sion-free survival of patients with advanced soft tissue sarcoma receiving either regimen of standard
202 hat the Hippo pathway is deregulated in many soft-tissue sarcomas, resulting in elevated expression o
204 the conventional staging of retroperitoneal soft tissue sarcomas (RPS) is essential in providing eff
205 o investigate the genetic basis for bone and soft-tissue sarcoma seen in routine clinical practice.
206 with doxorubicin and ifosfamide in resected soft-tissue sarcoma showed no benefit in relapse-free su
207 and neck carcinoma occurred in survivors of soft tissue sarcoma (SIR = 22.6), neuroblastoma (SIR = 2
209 renal cancer (SIR, 3.9; 95% CI, 2.0 to 7.5), soft tissue sarcoma (SIR, 2.6; 95% CI, 1.5 to 4.4), and
210 to 2,873 v SIR, 169; 95% CI, 115 to 239) and soft-tissue sarcomas (SIR, 542; 95% CI, 418 to 692 v SIR
212 In this presumed first prospective trial of soft tissue sarcoma spanning nearly the entire age spect
213 We applied this approach to 52 childhood soft tissue sarcoma specimens in an attempt to identify
216 to guide the multidisciplinary management of soft tissue sarcoma (STS) of the extremities, controvers
217 radiation therapy (IMRT) in the treatment of soft tissue sarcoma (STS) of the extremity is increasing
219 he American Joint Committee on Cancer (AJCC) soft tissue sarcoma (STS) staging system is more accurat
220 therapy in patients with first-line advanced soft tissue sarcoma (STS) to assess progression-free sur
221 s late toxicities in patients with extremity soft tissue sarcoma (STS) treated with preoperative imag
222 n (9-NC) in patients with advanced chordoma, soft tissue sarcoma (STS), and gastrointestinal stromal
223 Here, in a study of 18 canine patients with soft tissue sarcoma (STS), CIVO captured complex, patien
224 lung, such as renal cell carcinoma (RCC) and soft tissue sarcoma (STS), have an inherent capacity to
234 nocortical carcinomas (ACC), CNS tumors, and soft tissue sarcomas (STS) observed in 30%, 27%, 26%, an
235 in and pathogenesis of the majority of adult soft tissue sarcomas (STS) remains poorly understood.
236 currence rates for selected patients with T1 soft tissue sarcomas (STS) treated by surgery alone.
239 ET and CT response criteria in patients with soft-tissue sarcoma (STS) after combined chemotherapy pl
243 r predicting the histopathologic response of soft-tissue sarcoma (STS) to neoadjuvant isolated limb p
245 Unresectable metastatic bone sarcoma and soft-tissue sarcomas (STS) are incurable due to the inab
249 the activity of BMS-247550 in patients with soft tissue sarcomas (STSs) who had not received prior c
251 ally engineered autochthonous mouse model of soft-tissue sarcomas (STSs) to determine NG2/CSPG4's rol
252 therlands, who were enrolled in the European Soft Tissue Sarcoma Study Group (E pSSG) RMS 2005 study.
257 ion reduced tumor burden in a mouse model of soft-tissue sarcoma, suggesting that p53 strongly inhibi
259 (TILs) in leiomyosarcoma (LMS), a subtype of soft tissue sarcoma that exhibits histological heterogen
261 e in a genetically engineered mouse model of soft tissue sarcoma that loss of GCN2 has no effect on t
262 peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas that arise in connective tissue sur
263 ve sheath tumors (MPNST) are highly invasive soft tissue sarcomas that arise within the peripheral ne
264 LOH analysis of 160 cases of RMS and non-RMS soft tissue sarcomas that is at variance with convention
265 of care for adults who have the subtypes of soft tissue sarcomas that typically occur in pediatric p
267 Alveolar soft-part sarcoma (ASPS) is a rare soft-tissue sarcoma that is unresponsive to chemotherapy
268 habdomyosarcomas (ARMS) are highly malignant soft-tissue sarcomas that arise in children, adolescents
269 peripheral nerve sheath tumors (MPNSTs) are soft-tissue sarcomas that frequently arise in patients w
270 NSTs) represent a group of highly aggressive soft-tissue sarcomas that may occur sporadically, in ass
274 ologic response of osteosarcoma, Ewing's and soft tissue sarcomas to chemotherapy, and has correlated
275 t clinical benefit in patients with advanced soft-tissue sarcomas to support its use as a therapeutic
276 toperative Radiotherapy in Curable Extremity Soft Tissue Sarcoma) trial receiving preoperative radiat
277 in and ifosfamide for palliation of advanced soft-tissue sarcoma unless the specific goal is tumour s
278 t malignant neoplasms, particularly bone and soft tissue sarcomas, uterine leiomyosarcoma, melanomas,
280 , and T1-weighted MRI) from 51 patients with soft-tissue sarcoma was used to prospectively assess rep
281 clinical outcome of patients with metastatic soft tissue sarcomas, we compared a fixed dose rate infu
285 ive radiotherapy for patients with extremity soft tissue sarcomas were recently presented at the 2004
286 istologically confirmed diagnosis of bone or soft-tissue sarcoma were allocated on the basis of IGF-1
289 eterogeneity, and peritumoral enhancement of soft-tissue sarcomas were associated with grade III tumo
291 rential diagnosis of liposarcomas from other soft tissue sarcomas, whereas perilipin 2 correlates neg
292 ed trunk or extremity chemotherapy-sensitive soft tissue sarcoma, which were larger than 5 cm in diam
294 us tissue damage, in patients with extremity soft tissue sarcomas who receive once-daily preoperative
295 ival in patients with advanced or metastatic soft-tissue sarcoma who received eribulin with that in p
296 MR imaging examinations in 23 patients with soft-tissue sarcomas who had undergone neoadjuvant thera
300 habdomyosarcoma is the most common childhood soft-tissue sarcoma, yet patients with metastatic or rec