ライフサイエンスコーパス: soluble protein

1 ither chelating salt produced high levels of soluble protein.

2 le to synthesize 32, 20 of which resulted in soluble protein.

3 nd swelling capacity, and a 609% increase in soluble protein.

4 red state of ubiquitin, a small prototypical soluble protein.

5 n of membrane-embedded cholesterol and water-soluble proteins.

6 hand, resulted in moderate lipid binding to soluble proteins.

7 ainst one another is distinctive relative to soluble proteins.

8 distinguishable from that of the surrounding soluble proteins.

9 te the interactions of integral membrane and soluble proteins.

10 nalytical approaches than those employed for soluble proteins.

11 applicable within the field of poorly water-soluble proteins.

12 hese inclusions grow in size and incorporate soluble proteins.

13 l two-state model as found for many globular soluble proteins.

14 y associated membrane proteins are outwardly soluble proteins.

15 KR that is selectively defective for ERAD of soluble proteins.

16 thus far the method has been applied only to soluble proteins.

17 fe was the new incorporation of domains from soluble proteins.

18 recruit and structurally convert additional soluble proteins.

19 ensory proteins (CSPs) are a family of small soluble proteins.

20 amount role in the structure and function of soluble proteins.

21 acterizing the binding of small molecules to soluble proteins.

22 2D IR spectra relationships established from soluble proteins.

23 legumes that contain water- and dilute salt-soluble proteins.

24 abel-free fashion, the binding of ligands to soluble proteins.

25 e process), contrary to the behavior of most soluble proteins.

26 ually made with programs designed for use on soluble proteins.

27 sing techniques normally applicable only for soluble proteins.

28 function of membrane proteins, as it can for soluble proteins.

29 r the identification of cofactors for poorly soluble proteins.

30 stability, structure, and dynamics of water-soluble proteins.

31 proaches have been developed using globular, soluble proteins.

32 ion of membrane proteins lags behind that of soluble proteins.

33 sation and liquid-liquid phase separation of soluble proteins.

34 higher diffraction anisotropy than those of soluble proteins.

35 d and make use of existing functionality for soluble proteins.

36 ith extra membranous domains or fusions with soluble proteins.

37 ding inappropriate use of tools designed for soluble proteins.

38 least three different pools: (1) as unbound, soluble protein; (2) bound to presynaptic vesicles; and

39 he integral membrane protein NapA shows that soluble proteins acquire fewer lipid adducts.

40 olecular machines are utilized to move water-soluble proteins across these barriers.

41 anscription units encoding both membrane and soluble proteins adds to the evidence that the removal o

42 utcompeted in splenic GC responses against a soluble protein Ag and in mesenteric lymph node GC respo

43 s known about the assembly pathways by which soluble proteins aggregate into dense microdroplets.

44 n numerous medical conditions where normally soluble proteins aggregate into fibers [3, 4].

45 wNMR was sensitive to an increase in soluble protein aggregates in the range of <1.0%.

46 d different levels of C-terminal truncation, soluble protein aggregates, and glycation that all likel

47 inked to genotype, but with the advantage of soluble protein also being produced without the requirem

48 , a Lactobacillus rhamnosus GG (LGG)-derived soluble protein, ameliorates intestinal injury and colit

49 rotenoids content and low total phenolic and soluble protein amounts (p < 0.05).

50 ating different cytotoxic mechanisms between soluble protein and amyloid aggregates.

51 any drugs in blood, was used as both a model soluble protein and as an immobilized binding agent in a

52 ctivity in nanodiscs was higher than that of soluble protein and comparable with other heterologously

53 Each P. aeruginosa LT was expressed as a soluble protein and evaluated with a panel of substrates

54 Soluble protein and external aggregates are internalized

55 e concentration and enzyme treatment time on soluble protein and major allergenic proteins (Ara h 1 a

56 , SOD, POD, PPO, CAT activity, free proline, soluble protein and MDA contents fluctuated in response

57 e cheese and resulted in a higher content of soluble protein and release of amino acids at the 1st da

58 mutants show greatly decreased expression of soluble protein and/or increased aggregation.

59 ring high-resolution characterization of the soluble protein and/or its conformational dynamics, sugg

60 Out of 1736 soluble proteins and 2187 membrane-associated proteins i

61 We have studied the internalization of AL soluble proteins and amyloid fibrils into human AC16 car

62 tlas," a comprehensive proteomic database of soluble proteins and exosomal cargo SASP factors origina

63 differentiation by influencing secretion of soluble proteins and identify a molecular route that may

64 The soluble proteins and malondialdehyde (MDA) contents were

65 d to enrich for membrane proteins and remove soluble proteins and matrix interference.

66 analysis encompassed 38 myofibrillar and 46 soluble proteins and the rates of change in abundance, s

67 lar PDL1, such as on exosomes or as a freely soluble protein, and have shown that PDL1-expressing exo

68 t yeast prions are amyloid forms of normally soluble proteins, and a single protein sequence can have

69 ticles, ciliary gating for both membrane and soluble proteins, and axoneme assembly.

70 nant mechanism for artifactual inhibition of soluble proteins, and controls against it are now widely

71 amics, folding pathways, and interactions of soluble proteins, and is complementary to the high resol

72 itectures has long been recognized for water-soluble proteins, and this propensity has been rationali

73 onse so that in adult animals, codelivery of soluble protein antigens induces robust humoral, cellula

74 Concentration gradients of soluble proteins are believed to be responsible for cont

75 Approximately 10% of water-soluble proteins are considered kinetically stable with

76 Although molecular weights of water-soluble proteins are reliably determined from their SDS/

77 Cytokines and other secreted soluble proteins are routinely assayed as fluorescence i

78 At the TGN, soluble proteins are sorted based on the instructions ca

79 array of the trypanosome cytoskeleton while soluble proteins are washed away.

80 obial rhodopsin mimic, created using a small soluble protein as a template, that specifically photois

81 esults highlight the mammalian-expressed M2e soluble proteins as a promising vaccine development plat

82 architectural scaffolds and of membrane and soluble proteins as functional elements.

83 cation of CM inhibitors (chloroform/methanol soluble proteins) as main contributors of trypsin inhibi

84 ontrols the abundance of membrane-associated soluble proteins, as shown for abscisic acid (ABA) recep

85 ophylls, carotenoids, phenolic compounds and soluble proteins, as well as colour analysis, were evalu

86 The study of intact soluble protein assemblies by means of mass spectrometry

87 <0.05) over a range of pH's, exhibiting >30% soluble protein at pH 3 and 7 and 50-90% at alkaline pH,

88 g capacity, foaming density, and quantity of soluble proteins at pH 7.0 were observed.

89 on of poly ribosomes dominates at faster and soluble proteins at slower growth rates.

90 t of the effectors is controlled by a set of soluble proteins at the cytosolic interface of the membr

91 ogous expression platform that can produce a soluble protein-based vaccine in a manner compliant with

92 ing protein hydrogel triggered by mixing two soluble protein block copolymers, each containing one ha

93 h accumulation levels of around 10% of total soluble protein, but strikingly, another significant par

94 have made possible extensive engineering of soluble proteins, but designed beta-barrel membrane prot

95 e employed the high-throughput Expression of Soluble Proteins by Random Incremental Truncation (ESPRI

96 Here we applied ESPRIT (expression of soluble proteins by random incremental truncation), an i

97 Membrane proteins are distinguished from soluble proteins by their insertion into biological memb

98 ndoribonuclease L-PSP (Liver-Perchloric acid-soluble protein) by shotgun mass spectrometry analysis a

99 he in vivo mechanisms spiders use to convert soluble proteins, called spidroins, into insoluble fiber

100 processes: conformational changes within the soluble protein calmodulin, ligand binding to a G protei

101 for a lysosomal transport complex by which a soluble protein can target another protein for degradati

102 Certain soluble proteins can form amyloid-like prion aggregates.

103 We elucidate a mechanism of soluble protein cargo sorting into secretory vesicles wi

104 A mechanistic description for how soluble protein cargos are sorted into distinct vesicle

105 ples, with the following recoveries based on soluble protein: casein, 95-107%; soy protein, 92-97%, a

106 and reproducibly introduce sample containing soluble proteins/cells to the sensor.

107 more dynamic in the ps-ns timescale than any soluble protein characterized to date.

108 acterized systems, the fluorescently labeled soluble proteins cholera toxin B subunit-Alexa 647 and s

109 We measured their effects on a soluble protein complex, a membrane protein complex in d

110 Mass spectrometry (MS) of intact soluble protein complexes has emerged as a powerful tech

111 es that stabilize and direct the assembly of soluble protein complexes, but the mechanisms by which t

112 oniae, yielding 443 and 116 heteromultimeric soluble protein complexes, respectively.

113 A recombinant soluble protein comprising the ectodomain of Apo2 ligand

114 The soluble protein concentration did not vary between group

115 suppression by mouse tumor cells and that a soluble protein consisting of the extracellular domains

116 earning (DL) method originally developed for soluble protein contact prediction, which has been offic

117 The surface selectivity of CFH, a soluble protein containing 20 complement-control protein

118 Water-soluble protein content (WSPC) is a critical factor in b

119 The soluble protein content was expectedly lowered significa

120 significant reduction by 30-75% in the total soluble protein content, peptide content, and in-vitro p

121 Meanwhile, HT significantly increased soluble protein content, proline and malondialdehyde (MD

122 The GSH treatment remarkably improved soluble protein content, proline content, antioxidant en

123 icantly increased belowground biomass, total soluble protein content, transgene methylation levels in

124 idation of the molecular mechanisms by which soluble proteins convert into their amyloid forms is a f

125 ow that removing JDBD from JBP1 results in a soluble protein (Delta-JDBD) with the N- and C-terminal

126 ime, growth, Fv/Fm, tissue water content and soluble protein depletion occurred in comparison with NO

127 rements of dynamic light scattering, CD, and soluble protein depletion, the new analytical tools are

128 Although soluble protein design has advanced, membrane protein de

129 complete formation, peroxisomes import their soluble proteins directly from the cytosol using the new

130 sident protein anterior gradient-2 (AGR2), a soluble protein-disulfide isomerase involved in ER prote

131 Munc18-1 is a soluble protein essential for synaptic transmission.

132 5-fold in lysate; kcat increased >2.7-fold), soluble protein expression levels (up 60%), and thermost

133 The concentration of soluble proteins extracted by all the buffers from proce

134 multiwavelength electrophoretic profiles of soluble protein extracts from different quinoa grain var

135 accumulation of l-isoaspartate within water-soluble protein extracts primarily to crystallin peptide

136 Immunoblot analyses of soluble protein extracts revealed that ATR and other cel

137 Compared with chaperones that promote soluble protein folding, membrane protein chaperones req

138 effective strategy to help the production of soluble proteins for academic and industrial purposes.

139 lar APC-like phenotype and readily processed soluble proteins for cross-presentation of antigenic pep

140 Chaperone-mediated autophagy (CMA) targets soluble proteins for lysosomal degradation.

141 ortion of CD163 circulates in the blood as a soluble protein, for which no physiological function has

142 live Yersinia enterocolitica bacteria these soluble proteins form complexes both at the injectisome

143 Odorant binding proteins (OBPs) are small soluble proteins found in olfactory systems that are cap

144 the distribution of selenium in the aqueous soluble protein fraction and the detection of selenoamin

145 Perchlorate was removed by the soluble protein fraction at higher rates than nitrate.

146 However, the soluble protein fraction did not exhibit the same altere

147 myofibrillar fractions as well as in the non-soluble protein fraction due to the HP treatment, indica

148 and circular dichroism spectroscopy for the soluble protein fraction.

149 fractions of Azospira oryzae PS, as well as soluble protein fractions encapsulated in lipid and poly

150 Soluble protein fractions had activities of 15 400 to 29

151 as investigated using crude cell lysates and soluble protein fractions of Azospira oryzae PS, as well

152 eduction in terms of immunoreactivity within soluble protein fractions, up to 100%, which could be me

153 Globulin and albumin were the predominant soluble protein fractions.

154 sibility to perform the measurements just on soluble protein fractions.

155 added during the cell lysis stage can yield soluble protein from insoluble protein previously screen

156 le depots at neutral pH, efficiently release soluble protein from these depots when irradiated, and l

157 The concentration of total soluble proteins from heat treated shrimp increased sign

158 rehensive top down study of 152 IMPs and 277 soluble proteins from human H1299 cells including 11 087

159 ution was employed in order to extract water-soluble proteins from seed samples of oat, wheat and soy

160 alpha-klotho (KL), a transmembrane or soluble protein, functions as a co-receptor for Fibrobla

161 We recently demonstrated that a soluble protein, Gas6, can facilitate viral entry by bri

162 he effects on cell viability, the release of soluble proteins, glucidic colloids and amino acids in w

163 s (CyoB, CydB, MdlB, YidC, and LepI) and one soluble protein (GST), each fused to GFP, was examined.

164 s with site-directed spin labeling (SDSL) in soluble proteins has been well established.

165 tent with that previously observed for water-soluble proteins having comparable differences in solven

166 weight 16 kDa) is one of several small acid-soluble proteins highly expressed in medium spiny neuron

167 most all of this effort has focused on water-soluble proteins, however, leaving membrane proteins lar

168 wever, make expression of high quantities of soluble protein in bacterial systems difficult.

169 dicated partial membrane association of this soluble protein in both the leaves and internodes.

170 on their progressive ability to (1) produce soluble protein in Escherichia coli and (2) yield stable

171 tein fusions yield up to eight times more of soluble protein in Escherichia coli than fusions with se

172 ta define a mechanism of a probiotic-derived soluble protein in modulating intestinal epithelial cell

173 tag at the N-terminus and expressed it as a soluble protein in the cytoplasm of E. coli.

174 olds, compared with conventional delivery of soluble protein in vitro and in vivo.

175 hat initiates the aggregation of this highly soluble protein in vivo remains largely unanswered.

176 mational ensembles are enriched across water-soluble proteins in general, suggesting protein sequence

177 to investigate the light-induced response of soluble proteins in living bacterial cells.

178 ndicate RPGR regulates entry or retention of soluble proteins in photoreceptor cilia but spares the t

179 amic stabilities have been mostly limited to soluble proteins in purified systems.

180 tions in the levels of high molecular weight soluble proteins in Rpgr(ko) PSC.

181 s of interactions between membrane bound and soluble proteins in solution.

182 gy were identified for integral membrane and soluble proteins, indicating potential differences in as

183 Additionally, caspase assays revealed soluble protein induces apoptosis, demonstrating differe

184 hich together allow multiplexed screening of soluble protein interactions with lipid and membrane-emb

185 diseases are associated with conversion of a soluble protein into amyloid deposits, but how this is c

186 ecular basis and enables rapid conversion of soluble protein into fibrils.

187 can be used to convert natural and designed soluble proteins into allosteric molecular switches usef

188 The misassembly of soluble proteins into toxic aggregates, including amyloi

189 The ZIKV and DENV E protein expressed as a soluble protein is mainly a monomer that does not displa

190 Because the binding constant of soluble proteins is readily accessible in experiments, o

191 Although OCP is a soluble protein, it is able to quench the singlet oxygen

192 e bacterium Bordetella pertussis Secreted as soluble protein, it targets myeloid cells expressing the

193 ffect or modestly affected the level of most soluble proteins, it dramatically reduced the level of a

194 Although widely employed to study soluble proteins, its use remains negligible for membran

195 MP-associated MPO was enhanced compared with soluble protein, leading to potent inhibition of wound c

196 We validated our approach using three soluble protein-ligand systems (maltose binding protein,

197 , guaiacol peroxidase, superoxide dismutase, soluble protein, lignin, chlorophyll, and electric condu

198 on methods mainly focus on the extraction of soluble proteins, like rubisco protein, leaving more tha

199 e precise mechanism by which calreticulin, a soluble protein, localizes to the outer surface of the p

200 ent in three of the five ERMES subunits--the soluble protein Mdm12, the endoplasmic reticulum (ER)-re

201 -1, one approach involves using recombinant, soluble protein mimics of the native trimer.

202 cally accelerate the aggregation of normally soluble protein molecules into amyloid fibrils and alter

203 rlying kinetic basis for a classic cytosolic/soluble protein moving in slow axonal transport and reve

204 ecombinant C. tepidum BchC was purified as a soluble protein-NAD(+) complex.

205 t-lesional AAV-assisted co-expression of two soluble proteins, namely insulin-like growth factor 1 (I

206 de facto analyzer for solution and membrane-soluble protein native mass spectrometry (MS) studies; t

207 embrane protein Niemann-Pick C1 (NPC1) and a soluble protein, Niemann-Pick C2 (NPC2).

208 Human L-ficolin is a soluble protein of the innate immune system able to sens

209 n proteins of different sizes and found that soluble proteins of 150 kDa and membrane proteins with a

210 sm), and isoelectric focusing (IEF) of water-soluble proteins of fish fillet were applied successfull

211 ions is approximately 30% lower than that of soluble proteins of similar mass.

212 ies we have identified FKBP20-2 and CYP38 as soluble proteins of the chloroplast thylakoid lumen that

213 y, we apply these EPR methods to small water-soluble proteins, of the type for which the existence of

214 ept by detecting femtomoles (10(-15) mol) of soluble protein oligomers prefractionated by size exclus

215 e II diabetes share common features of toxic soluble protein oligomers.

216 high irradiance or storage of N in leaves as soluble protein or amino acids.

217 cell lysates and extracellularly, either as soluble proteins or in lymphocyte-derived extracellular

218 sets, immunoactivation markers, inflammatory soluble proteins, or cellular markers of latently infect

219 oads and measuring the plasma levels of >600 soluble proteins, our data highlight the importance of T

220 Further, even if trained mostly by soluble proteins, our deep learning method works very we

221 (+) of CD8(+)) compared to immunization with soluble protein, ovalbumin and polymer mixture, and the

222 l other distinct PC-expressing bacteria or a soluble, protein-PC conjugate.

223 es, a large family of highly versatile small soluble proteins, play crucial roles in defining innate

224 d dramatically enhance the solubilization of soluble proteins (PN), polysaccharides (PS), nucleic aci

225 ds in one day, a speed equivalent to that of soluble protein production.

226 This 35 kDa water-soluble protein provides specific environment for blue-g

227 membrane-bound were distinguished from water-soluble proteins (Q2 = 87% +/- 1).

228 Immunological analyses of 23 soluble proteins related to chemotaxis and inflammation

229 crease in TNF-alpha message, mRNA stability, soluble protein release, and membrane expression in ADAM

230 ry structure determination for transmembrane/soluble proteins requires a reliable computational proto

231 function with diverse substrates: the yeast soluble proteins Rpn10 and Rvs167, and the human recepto

232 anded cottonseed meal, respectively, and one soluble protein samples (Gd-P) in a pilot scale from gla

233 measured antioxidant activities of two water soluble protein samples (Gl-L and Gd-L) isolated in a la

234 ocated in the spore core known as small acid-soluble proteins (SASP).

235 , we engineered the EL1 and EL2 loops onto a soluble protein scaffold, mapping specific ligand and lo

236 tions reveal the dynamic mechanisms by which soluble proteins self-organize into condensed microdropl

237 ct ESI-MS comparison of lipid binding to the soluble protein serum albumin and to the integral membra

238 Mucilage (M) and soluble protein (SP) extracted from chia seed and flaxse

239 Amyloid formation involves the conversion of soluble protein species to an aggregated state.

240 Spider silk fibers are produced from soluble proteins (spidroins) under ambient conditions in

241 gulated limits (30-35 mg/100 g muscle), salt-soluble protein (SSP) decreased systematically and total

242 Salt-soluble protein (SSP) significantly decreased when chopp

243 on strategies employ unfolded or native-like soluble protein standards with masses and mobilities com

244 io methods for low-resolution restoration of soluble protein structure from small-angle scattering da

245 ere developed using information derived from soluble protein structures.

246 proteins, such as IgM natural antibodies and soluble proteins, such as C-reactive protein and complem

247 hat exogenously added lipids did not bind to soluble proteins, suggesting that lipids have a low prop

248 Salt-soluble protein, surface reactive sulfhydryl content, an

249 Although it is known that cytosolic/soluble proteins synthesized in cell bodies are transpor

250 ength, thus bearing a greater resemblance to soluble proteins than previously recognized.

251 NPC2 is a 16-kDa soluble protein that binds cholesterol in a 1:1 stoichio

252 e Orange Carotenoid Protein (OCP) is a water-soluble protein that governs photoprotection in many cya

253 n-induced cytidine deaminase (AID), a poorly soluble protein that is essential for antibody diversifi

254 Tau is normally a soluble protein that stabilizes microtubules, with splic

255 age from sub-10-mum crystals of membrane and soluble proteins that are difficult to crystallize, whil

256 n Mycobacterium tuberculosis emphasize water-soluble proteins that are secreted into the extracellula

257 Cytokines are a large class of soluble proteins that dimerize transmembrane receptors i

258 components, including membrane proteins and soluble proteins that interact with ligands or receptors

259 location, immune activation, and presence of soluble proteins, that modulate the hepatic cytokine env

260 dy are comparable to those observed in water-soluble proteins, the H-segment of the leader peptidase

261 Because BamD and LptE are both soluble proteins, the simplest model consistent with the

262 , M-CSFM and three variants were produced as soluble proteins; their affinity and structure were anal

263 For soluble proteins, these complexes arise from nonspecific

264 Given that MICB*002 is a low expresser of soluble proteins, these data indicate that surface expre

265 hat lysine is favoured over arginine in more soluble proteins, this suggests that individual domains

266 ulated very high GUS levels (up to 10% total soluble protein) throughout the plant, within 3 d of a 1

267 000 phytase activity units (FTU) per gram of soluble protein, thus demonstrating the feasibility of d

268 c and induced hPS cell lines when added as a soluble protein to the medium at seeding.

269 otein, and (3) on the ability of the stable, soluble proteins to adopt the target fold.

270 en that S-acylation facilitates anchoring of soluble proteins to cell membranes, our findings suggest

271 mixtures of glycolipids (GLs) against water-soluble proteins to detect specific interactions.

272 he processes that influence binding of water-soluble proteins to GLs incorporated into NDs and to exp

273 g whether amyloid deposition causes normally soluble proteins to misfold.

274 ed from standard calibration protocols using soluble proteins, to values measured using an RF-confine

275 compartmentalized signaling; however, unlike soluble protein trafficking, processes targeting integra

276 We show that these soluble proteins traverse the Golgi much faster than pro

277 the cells and act as a recruitment point for soluble protein, triggering the amyloid fibril elongatio

278 This small, soluble protein triggers a host of biological effects up

279 BvLz accumulation reached 1.4% of total soluble protein (TSP) (10.0 mg BvLz/kg culm mass) in sta

280 produced and yields are up to 1.8% of total soluble protein (TSP) in transformed rice cells.

281 the minutes to hours timeframe observed for soluble proteins under the same culture conditions.

282 We report the expression of a soluble protein V that exists in monomer-dimer equilibri

283 also demonstrate direct interaction between soluble proteins V and VI, thereby revealing the bridgin

284 Following infusion of soluble protein, various cell types were imaged ingestin

285 rophosphatases (PPase), also called vacuolar soluble proteins (VSPs), which are localized to its acid

286 Purification of EVs from soluble protein was determined by calculating the ratio

287 Soluble protein was extracted from wheat flour, and glut

288 ysicochemical properties of the minces (salt-soluble proteins, water holding capacity, structural wat

289 Furthermore, the soluble proteins were exposed to remarkable structural c

290 Soluble proteins were extracted from common wheat flour

291 The current work demonstrates that water soluble proteins were used to substantially increase the

292 nant peptide accumulation of up to 1 % total soluble protein when the Os.hb2 promoter was used.

293 tion experiments demonstrated that CtsE is a soluble protein while CtsP is membrane associated in C.

294 erminant receptors (GRs), while SpoVAEa is a soluble protein with no obvious signals to allow its pas

295 Amyloid fibrils formed from initially soluble proteins with diverse sequences are associated w

296 and consequences of the association of water-soluble proteins with membranes is fundamental to unders

297 tion with beclin 1 was competed for by other soluble proteins with polyQ tracts in a length-dependent

298 Interactions of soluble proteins with the cell membrane are critical wit

299 teins, along with 163 membrane-associated or soluble proteins, with a median q value of 3 x 10(-10).

300 is a modification sufficient for trafficking soluble proteins within the phagocytic/endocytic network