ライフサイエンスコーパス: solute

1 with a quantum mechanical description of the solute.

2 ach carrying a small amount of the delivered solute.

3 osed to high concentrations of extracellular solute.

4 a halochloris is limited to using compatible solutes.

5 xtrapolating beyond the subset of considered solutes.

6 n important role in the transient storage of solutes.

7 ontrolling their retention compared to small solutes.

8 ve or long-range diffusion of substitutional solutes.

9 ter, whilst wider channels permit passage of solutes.

10 iated distribution of nanoparticles or other solutes.

11 nnected and communicate through this pool of solutes.

12 cy arteriolar oscillations drive drainage of solutes.

13 nd how this affects the retention of several solutes.

14 re pores to achieve high selectivity between solutes.

15 res for precise separation of ions and small solutes.

16 ed Coulomb interactions only between charged solutes.

17 have focused on the crystallization of pure solutes(6,7) and the effects of single growth modifiers(

18 However, solute accumulation at the heating interface has severel

19 a high affinity for a wide range of organic solutes, achieving >95% encapsulation efficiency for hyd

20 operties from bulk soil, affecting water and solute acquisition by plants.

21 dynamics simulations, we are able to screen solutes across a wide range of chemistries and polaritie

22 that mediate the selective translocation of solutes across biological membranes.

23 ions and controls the selective transport of solutes across it and associated lymphoid tissues that p

24 e to molecular-mechanics calculations on the solute alone; as such, they can be incorporated into MD

25 as to probe the concentration profile of the solute and analyze the impact of operating parameters, s

26 her are similar in strength to those between solute and solvent.

27 e developed the first computational model of solute and water transport from Bowman space to the papi

28 ents were performed for a total of 12 single solutes and 55 bisolutes onto two widely used resins (MN

29 on to the host vasculature to exhaust water, solutes and carbohydrates.

30 Here, we determine the source of major solutes and carbon to Lake Untersee, evaluate the carbon

31 e interstitial fluid space rapidly transport solutes and clear waste from brain.

32 n revealed that EcYfdC can transport neutral solutes and could possibly be involved in the transport

33 Here, we investigate the influence of small solutes and lipid bilayers, both constituents of all bio

34 ole in preventing the backflow of reabsorbed solutes and water to the tubular lumen, as well as in co

35 nonstructural carbohydrates, photosynthesis, solute, and water potential were measured, and carbon ex

36 include exclusion of colloidal and molecular solutes, and characteristic light absorbance at 270 nm.

37 endothelial sieving, and transport of fluid, solutes, and particulates complicate interpretations in

38 ntioxidants, gut microbiome products, uremic solutes, and uremic toxins.

39 high producers is a constitutive compatible solute; and (2) DMSP production in low producers is a fi

40 Interactions between solvents and solutes are a cornerstone of physical organic chemistry

41 ce of advection in neuropil is contested and solutes are claimed to be transported by diffusion only.

42 teractions between the droplet and enzymatic solutes are important to achieve certain functions.

43 Classically, solutes are modeled using reaction-advection-diffusion k

44 e passively permeable to various hydrophilic solutes as large as 40 kDa, in contrast to synthetic gia

45 entrations of endogenous candidate secretory solutes at baseline, using targeted liquid chromatograph

46 fied by the segregation enthalpy spectrum-of solute atoms at GB sites in polycrystals, based solely o

47 The segregation of solute atoms at grain boundaries (GBs) can profoundly im

48 e dynamic interplay between dislocations and solute atoms.

49 ng process that results in the clustering of solute atoms.

50 nsitive in frozen soils, as liquid water and solute availability decrease rapidly with declining temp

51 ClO(4), it was found that the diffusivity of solute becomes positively correlated to the average mesh

52 Here we show that the solute binding lipoprotein PiuA from the piu Fe acquisit

53 consistent with recent descriptions of other solute binding proteins of type II ABC transporters.

54 ng an l,d-transpeptidase, an ABC transporter solute-binding protein, and a methionine sulfoxide reduc

55 , and they are functionally categorized into solute-binding proteins, oxidoreductases, cell envelope

56 ding but decreases with solution crowding by solutes, both of which we confirm with molecular dynamic

57 Under unsaturated conditions, the solute breakthrough curves show early arrivals and very

58 e, sodium fluorescein, and ~ 120% for larger solutes, BSA and Dex-70k.

59 not only the polarity and the volume of the solutes but also their HB-accepting ability, the main fa

60 f the oil phase and allows concentrating the solute by altering relative lengths of the sender and re

61 The secretion of organic solutes by the proximal tubules is an essential intrinsi

62 precipitates from just miniscule amounts of solute can invoke simultaneous high strength and ductili

63 n the background electrolyte and an injected solute can limit or enhance the reactant delivery, cause

64 ting NTO reduction rate, and illustrates how solutes can shift the LFER by interacting with either ir

65 are affected, including those controlled by solute carrier (SLC) and ATP-binding cassette (ABC) tran

66 A plasma membrane transporter, the solute carrier (SLC) human multidrug and toxin extrusion

67 multiple amino acids and their transporters, solute carrier (SLC) members.

68 With more than 400 members, the solute carrier (SLC) membrane transport proteins are the

69 roup of membrane proteins that belong to the solute carrier (SLC) superfamily.

70 OATP2B1, a member of the solute carrier (SLC) transporter family, is an important

71 n to develop prodrug molecules, which hijack solute carrier (SLC) transporters for active transport i

72 There are over 420 human solute carrier (SLC) transporters from 65 families that

73 peptidyl-prolyl cis-trans isomerase (PPIF), solute carrier 15 (SLC15), solute carrier family 43 memb

74 Members of the solute carrier 15 family (SLC15) transport di- and tripe

75 The solute carrier 16 (SLC16) family represents a diverse gr

76 Members of the solute carrier 17 (SLC17) family use divergent mechanism

77 The human solute carrier 22A (SLC22A) family consists of 23 member

78 on electrochemical gradient, as found in the solute carrier 36 family of proton-coupled amino acid tr

79 ZIP14 (encoded by the solute carrier 39 family member 14 (SLC39A14) gene) is a

80 esults reveal the principles of glycoprotein-solute carrier assembly and provide templates for improv

81 reabsorbed through the concerted actions of solute carrier channels and aquaporins at various positi

82 The neutral amino acid transporter solute carrier family 1 member 5 (SLC1A5 or ASCT2) is ov

83 The solute carrier family 13 (slc13) transporters mediate tr

84 n 1 protein (EPAS1, also called HIF2A), CA9, solute carrier family 16 member 4 (SLC16A4, also called

85 Solute Carrier Family 19 Member 2 (SLC19A2) encodes thia

86 ICI and the neighboring protein-coding gene, solute carrier family 2 member 3 (SLC2A3) which encodes

87 glucose transporter 1 (Glut1), also known as solute carrier family 2, facilitated glucose transporter

88 requency (MAF) = 25-44%; P < 3 x 10(-14)) of solute carrier family 2, member 9 (SLC2A9) and rs4148145

89 Solute carrier family 20 member 2 (SLC20A2) and xenotrop

90 In mice, the gene encoding Mfrn1, solute carrier family 25 member 37 (Slc25a37), is highly

91 he mitochondrial fusion-fission-related gene solute carrier family 25 member 46 (Slc25a46) and treate

92 The anion-conducting transporter solute carrier family 26 member 9 (SLC26A9) is a promisi

93 -acetylneuraminic acid synthetase (Cmas) and solute carrier family 35 member A1 (Slc35a1), promote si

94 ulfate proteoglycan synthesis encoded by the solute carrier family 35 member B2 gene (SLC35B2).

95 the cytoplasmic tail of the human lysosomal solute carrier family 38 member 9 (SLC38A9) destabilizes

96 We studied the functions of the solute carrier family 39 member 4 (SLC39A4, also called

97 f this is a single-nucleotide variant in the Solute Carrier Family 39 Member 8 (SLC39A8) gene encodin

98 work in our laboratory has revealed that the solute carrier family 39 member A2 (SLC39A2/ZIP2) increa

99 Significant downregulation of solute carrier family 43 A3 (SLC43A3), an equilibrative

100 isomerase (PPIF), solute carrier 15 (SLC15), solute carrier family 43 member 1 (SLC43A1), and solute

101 the angiotensin I-converting enzyme 2 (ACE2)-solute carrier family 6 member 19 (SLC6A19) dimer.

102 ed the functions of the creatine transporter solute carrier family 6 member 8 (SLC6A8, also called CR

103 te carrier family 43 member 1 (SLC43A1), and solute carrier family 7 member 11 (SLC7A11).

104 AD(P)H quinone dehydrogenase 1) and SLC7A11 (solute carrier family 7 member 11), decreased the GSH/GS

105 Solute carrier family 7 member 2 (SLC7A2, also known as

106 Pathogenic mutations in the solute carrier family 7 member 5 (SLC7A5) gene, which en

107 x/WD repeat-containing protein 7 (Fbxw7) and solute carrier family 9 member 3 (Slc9a3).

108 dentified numerous variants of the endosomal solute carrier family 9 member A6 (SLC9A6)/(Na(+),K(+))/

109 id transporter 1 (LAT1), which is encoded by solute carrier transporter 7a5 (Slc7a5), plays a crucial

110 Solute carriers (SLC) and ABC transporters represented a

111 In eukaryotes the SLC35 family of solute carriers are responsible for their selective upta

112 ce has highlighted the importance of various solute carriers to the toxicity of anticancer drugs, the

113 These proteins comprise several solute carriers, such as the ATP/ADP antiporter nucleoti

114 to significant changes in the expression of solute carriers, such as the urea transporters encoded b

115 d Lake Untersee largely determines the major solute chemistry of the oxic water column with plagiocla

116 activities, indicating that the presence of solutes (citric acid and NaCl) after 27 kJ/cm(3) reduced

117 Secretory solute clearance measurements can predict kidney drug cl

118 regression to test associations of secretory-solute clearances with CKD progression and mortality, ad

119 score as the scaled average of the secretory solute clearances.

120 olution strengthening, another one mimicking solute cloud formation, and a third one where dislocatio

121 formation, and a third one where dislocation/solute coevolution leads to jerky flow as a precursor of

122 silica particles; the partitioning of model solutes compares favorably to that in lipid vesicle memb

123 Ectoine is a solute compatible with the physiologies of both prokaryo

124 ontent of biological secretions, their small-solute composition impacts the potency of antiviral micr

125 an be associated with alterations in urinary solute composition including hypercalciuria.

126 the spontaneous Raman spectra, and the total solute concentration from the refractive index retrieved

127 mic conditions, and feed temperature, on the solute concentration profile in the boundary layer.

128 ff)) was determined from the spatio-temporal solute concentration profiles using an unsteady diffusio

129 nterfacial tension which was affected by the solute concentration was responsible for the velocity di

130 produced, while imaging the evolution of the solute concentration with time at any given point within

131 ayers exhibits a quadratic dependence on the solute concentration, characteristic of the second-order

132 ese dependences enable quantification of the solute concentration.

133 exposure to decreased pH combined with high solute concentrations in the unfrozen water of frozen me

134 f culture media and the resulting changes in solute concentrations over time; as water evaporates fro

135 Animals tightly regulate blood volume and solute concentrations.

136 es the interplay between strong short-ranged solute core interactions, local hydrogen-bond configurat

137 R) and related methods may be used to obtain solute-correlated spectra revealing solute-induced pertu

138 oupling FN to RAST and requiring only single-solute data was proposed.

139 transport of biocidal metal cations and soil solutes, degradation and loss of crystallinity of cellul

140 uid chromatography (SFC), the retention of a solute depends on the temperature, density, pressure, an

141 Partition coefficients of solutes differing in hydrodynamic radius were consistent

142 The effective solute diffusion coefficient of brain tissue (D(eff)) wa

143 t (solute-network) H-bonding contribution to solute diffusion from the indirect contribution arising

144 nder load, which depends on metabolic rates, solute diffusion, and disc morphometry, remains unknown.

145 entally determined TMJ disc metabolic rates, solute diffusivities, and disc morphometry, and through

146 Modulation of solute diffusivity and ECS could explain diverse outcome

147 ne crystals, an inversion centre, emerges in solute dimers extant in solution prior to crystallizatio

148 n microstructures, concurrent precipitation, solute drag, grain growth and texture evolution are disc

149 the case of a charged particle and an ionic solute (e.g., table salt, NaCl), previous studies have p

150 icular elution mechanism observed with large solutes (e.g., proteins) in liquid chromatography, colum

151 ny bacterial cells accumulate the compatible solute ectoine and its derivative 5-hydroxyectoine.

152 the absorption and disposition of a range of solutes, eight SLC22A family members remain classified a

153 ps and very short steep gradient segments at solute elution allows one to set the selectivity as desi

154 nner bubble pressure, which defines a bubble solute exchange with ambient porewaters.

155 provided >=1 24-h urine sample, and urinary solute excretion was analyzed.

156 However, despite the continuously elevated solute excretion, long-term osmotic diuresis does not oc

157 AFFF are similar to rates observed in single-solute experiments.

158 ntries such as Brazil) due to retardation in solute flow associated with the fine root system and the

159 aize increased nitrate loss through enhanced solute flow bypassing the soil matrix.

160 oss these scales are what ultimately control solute flux to the Arctic Ocean.

161 t membranes to selectively separate a single solute from a mixture of solutes is limited.

162 barrier (BBB) tightly regulates the entry of solutes from blood into the brain and is disrupted in se

163 energy required for constant reclamation of solutes from crude blood filtrate.

164 (2020) show that elimination of solutes from the brain along arterial walls is driven by

165 The flux of solutes from the chemical weathering of the continental

166 are at the core of processes for separating solutes from water, such as water purification and desal

167 In addition, several compatible solutes (glycerol, Pro, and Suc) accumulated to high lev

168 Small solutes have been shown to alter the lateral organizatio

169 cess electrons in liquids-archetypal quantum solutes-have been largely restricted to very dilute elec

170 ce of kynurenic acid, a highly protein-bound solute, having the strongest association.

171 quired to maintain neuronal activity-related solute homeostasis at the axon-myelin interface, and the

172 robe the competing energetics of inserting a solute in different membrane environments by means of th

173 ferential partitioning behavior of the model solute in two-layer gels, providing insight into the tra

174 an force between ionic or apolar hydrophobic solutes in dilute aqueous solutions described by standar

175 ly, we quantified eight endogenous secretory solutes in plasma and urine using liquid chromatography-

176 aphy (TRLC) allows for separation of organic solutes in purely aqueous mobile phases whereby retentio

177 to the on/off mechanism observed with large solutes in RPLC (S values were higher than 100 for intac

178 oefficients of various fluorescently labeled solutes in single-layer and multilayer open hydrogels.

179 e for the ventricles as a source or sink for solutes in the brain.

180 aracterized by the accumulation of water and solutes in the enlarging cells of parenchymatous tissues

181 embranous compartments that separate reduced solutes in the external medium from an encapsulated acce

182 es that actively alter the concentrations of solutes in the extracellular space.

183 We reveal that solutes in the solution, pH value of the solution and th

184 ibuted in the reference material (e.g., many solutes in thermodynamic equilibrium).

185 ergy (in the form of glucose) and additional solutes (in the form of Na(+) and its accompanying anion

186 est that channel gating involves a change in solute-inaccessible volume in the CTD of ~1,900 angstrom

187 Paravascular drainage of solutes, including beta-amyloid (Abeta), appears to be a

188 nd that lipid bilayers, in contrast to small solutes, increase the rate of cavitation, which remains

189 o obtain solute-correlated spectra revealing solute-induced perturbations of water structure, such as

190 ilic/psychrotolerant bacteria under diverse, solute-induced stresses (Brochothrix thermosphacta, Ente

191 r stress including low water activity, other solute-induced stresses, and dehydration-rehydration cyc

192 ss rat brain tissue of fluorescently-labeled solutes injected through the carotid artery after tDCS.

193 onsidering a dynamic material, we scrutinize solute interactions with a UV photoactive polyacrylamide

194 dodermis to direct the movement of water and solutes into and out of the vascular system in roots.

195 stripping or ion exchange if the proper draw solute is chosen.

196 pirically observed that the diffusion of the solute is counter to that of the solvent i.e. there is s

197 FO applications where a limited use of draw solute is necessary.

198 y separate a single solute from a mixture of solutes is limited.

199 the kidney's clearance of tubular secretory solutes is uncertain.

200 r adjustment, lower kidney clearances of six solutes-kynurenic acid, pyridoxic acid, indoxyl sulfate,

201 generated along the solid boundary as dense, solute-laden fluid descends under gravity.

202 reduced appressorial adhesion, which led to solute leakage.

203 Thermodynamic partitioning dictates solute loading and release from a hydrogel.

204 lvent fluctuations in the solvation shell of solute molecules attaching to the crystal surface.

205 zation to obtain high resolution between the solute molecules of interest.

206 ive activation energy values for the various solute molecules.

207 c theory is proposed to separate the direct (solute-network) H-bonding contribution to solute diffusi

208 centrated SSs apart from traditional solvent-solute ones.

209 Instead, we track a bolus of solutes or nanoparticles using particle tracking based p

210 iruses is governed by the cumulative dose of solutes or the product of concentration and time, as in

211 Groundwater solutes originates from various sources such as atmosphe

212 s in acyl-chain structure (disordering) with solute partitioning.

213 gnificant in the case in which an immiscible solute (pentane) was mixed with H(2)O.

214 We show accurate prediction of solute permeabilities at physiological temperature using

215 e characterized for water permeability ( A), solute permeability ( B), and structural parameter ( S).

216 d type 2 diabetes-induced glomerular albumin solute permeability (Ps'alb).

217 at maintains brain homeostasis and regulates solute permeability into brain tissue.

218 R) selectivity filter, is thought to control solute permeability: previous studies on single represen

219 PAH[4]'s unique properties of a high water/solute permselectivity via cooperative water-wire format

220 The crystallizing solute phase was characterized by low temperature powder

221 Solid- and solute-phase geochemical analyses combined with modeled

222 me-catalysis-induced positive chemotaxis and solute-phospholipid-based negative chemotaxis.

223 ic biomass surfaces so as to match the local solute polarity.

224 liquid phase separation into solute-rich and solute-poor phases is a fundamental step leading to the

225 s depends on a complex interplay between the solute, pore size, and polarity, and that using single w

226 tein nanopores, aquaporins and related polar solute pores, and a number of different classes of ion c

227 ations are linked to decreased levels of key solute processing and transporting factors in the brush

228 ne the intestinal tract, are specialized for solute processing and uptake.

229 suggests that tubular clearance of secretory solutes provides additional information about kidney hea

230 score (24.1%); MPEs for individual secretory solutes ranged from 27.3% to 48.0%.

231 ng the water permeance while maintaining the solute rejection of a nanofiltration (NF) membrane can p

232 novel mode of inhibitor binding and show how solutes release is coupled to protein conformational cha

233 sodium in 2 hours with negligible off-target solute removal and overall stable serum electrolytes.

234 e concentrations were stable, and off-target solute removal was negligible.

235 quantities of sodium with limited off-target solute removal.

236 The robustness of the solute retention was lowest when operating the systems a

237 how that liquid-liquid phase separation into solute-rich and solute-poor phases is a fundamental step

238 zzling, mesoscopically sized inclusions of a solute-rich liquid, well outside the region of stability

239 well outside the region of stability of the solute-rich phase.

240 a limited understanding of the variation of solute segregation tendencies across the full, multidime

241 ns-in theory-just broaden the peaks of large solutes since a great part of the column only acts as vo

242 ngle X-ray scattering, which is sensitive to solute size and shape and has millisecond temporal resol

243 w rejection to near-perfect rejection over a solute size range smaller than half Angstrom.

244 tDCS, D(eff) increased by ~ 10% for a small solute, sodium fluorescein, and ~ 120% for larger solute

245 Herein, we demonstrate that precise solute-solute separation can be achieved using polyamide

246 S) model, with truncated solvent-solvent and solute-solvent Coulomb interactions and long-ranged but

247 leads to the possibility of amplifying these solute-solvent effects and will shed light on extremely

248 Nevertheless, the solute-solvent interactions associated with their highly

249 a renewed interest in fundamental aspects of solute-solvent interactions has been sparked in the fiel

250 olecular polymers offer to gain insight into solute-solvent interactions have become clear relatively

251 As a result, many exciting effects of solute-solvent interactions in modern physical organic c

252 e, and the PE/PPE proteins apparently act as solute-specific channels.

253 an perspective of GS transport revealed that solute speed was faster in CSF compared to grey and whit

254 demonstrated 2-fold differences in regional solute speed within the brain.

255 ossible with single-molecule observations of solute-stationary phase interactions.

256 We find that the high solute strength of the aerosol particles significantly e

257 ilute aqueous solutions, and not at the high solute strengths of atmospheric aerosol particles.

258 The accumulation of organic compatible solutes such as glycine betaine does not perturb the fun

259 time; as water evaporates from the droplets, solutes such as sodium chloride in the media become more

260 osmolytes such as KCl and membrane-permeable solutes such as weak acids.

261 rticular location to pollution from reactive solutes, such as nitrate, is determined by the interplay

262 aled reduced abundances of foliar compatible solutes, such as sugars and sugar alcohols, whereas nitr

263 Osmolytes are organic solutes that change the protein folding landscape shifti

264 These processes are perturbed by solutes that interact with these atoms differently than

265 adhesion and dysfunction of the movement of solutes through the paracellular spaces in the neurovasc

266 er kidney clearances of endogenous secretory solutes to be associated with CKD progression and all-ca

267 hering contributing < 5% of the Ca(2+)-Na(+) solutes to the lake.

268 al porin proteins for the transport of small solutes to the periplasm.

269 n the thermodynamic equilibrium state of the solutes toward the gel phase.

270 Solute transfer was measured while simultaneously monito

271 Water and solute transport across epithelia can occur via the tran

272 ly, attentions should be paid when modelling solute transport by the classical advection-diffusion eq

273 eeking to represent lateral and longitudinal solute transport in rapidly changing Arctic landscapes.

274 del of cerebral small vessel disease (cSVD), solute transport in the perivascular spaces (PVS) and PV

275 Solute transport in unsaturated porous materials is a co

276 Solute transport modelling further demonstrates how incr

277 yet needs to be included in the Darcy-scale solute transport models.

278 either essential for signal transduction and solute transport or function as scaffold structures.

279 in this work systematically investigate the solute transport process in a simple porous medium model

280 l tubule for many commonly studied water and solute transport proteins and metabolic enzymes matched

281 hy (sCT) we obtained detailed information on solute transport through a glass bead packing at differe

282 nisms that contribute to energy barriers for solute transport through subnanometre pores.

283 fully coupled model of flow, heat transport, solute transport, and the geochemical reaction network t

284 port, pexophagy, matrix protein degradation, solute transport, signaling, redox homeostasis and vario

285 ately, the core kidney function of selective solute transport.

286 ocholate cotransporting polypeptide, organic solute transporter alpha/beta) in several cell lines [Hu

287 ructures, we propose that Rv1819c is a multi-solute transporter for hydrophilic molecules, analogous

288 protein (IBABP) and then released by organic solute transporter OSTalpha/beta.

289 iona`l codes driving regional specification, solute transporter program activation and terminal diffe

290 nsisting of tfap2b, irx1a and genes encoding solute transporters that dictate the specialized metabol

291 nts each expressing a distinct repertoire of solute transporters.

292 Solute transporting epithelial cells build arrays of mic

293 rgency release valve discharging cytoplasmic solutes upon osmotic stress.

294 itical for epithelial homeostasis, including solute uptake and host defense.

295 to the atomic scale diffusion mechanisms of solute-vacancy clusters.

296 grade biopolymers into bio-available smaller solutes, while oligotrophic bacteria usually cannot.

297 nally efficient proxy to establish whether a solute will stabilize or destabilize domain phase separa

298 height without solvent-based focusing for a solute with modest retention enthalpy.

299 lood) osmolality (i.e., its concentration of solutes), with bacterial growth being slower in protein-

300 IP exhibits highly size-dependent sieving of solutes, yielding a step-wise transition from low reject