ライフサイエンスコーパス: sorting signal

1 that targets proteins displaying a cell wall sorting signal.

2 elivered to the vacuole using ubiquitin as a sorting signal.

3 h carries an in-frame fusion of Ub as an MVB sorting signal.

4 signal peptide and a C-terminal LPXTG motif sorting signal.

5 llest essential component of its basolateral sorting signal.

6 ting their recognition of the ubiquitin (Ub) sorting signal.

7 threonine and the glycine of its NPKTG motif sorting signal.

8 ossesses a new distinct C-terminal cell wall sorting signal.

9 is hexapeptide acts as a sterol-regulated ER sorting signal.

10 it a nascent helix encompasses the lysosomal sorting signal.

11 effects of blocking the rhodopsin C-terminal sorting signal.

12 ct to binding of cargo with a tyrosine-based sorting signal.

13 strates that possess an LPXTG-type cell wall sorting signal.

14 immunoglobulin binding protein with an LPXTG sorting signal.

15 Sed5 molecules, as well as to the DxE cargo-sorting signal.

16 rd intracellular loop contains a basolateral sorting signal.

17 eraction motif and a putative tyrosine-based sorting signal.

18 xyl-terminal sequence, which encodes a novel sorting signal.

19 reorganization of the binding pocket for the sorting signal.

20 aid to N-linked glycosylation as a potential sorting signal.

21 transit peptide but has a distinct envelope sorting signal.

22 howed that this sequence acts as a recycling sorting signal.

23 wn function 1542) and a C-terminal cell wall sorting signal.

24 pace by proteolytic removal of a hydrophobic sorting signal.

25 nchors proteins bearing a noncanonical LPNTA sorting signal.

26 in discrete tER sites depends upon positive sorting signals.

27 ously unrecognized diversity among dileucine sorting signals.

28 afficking mechanisms of D/EXXXL[LI]-mediated sorting signals.

29 ernalization mediated by the dileucine-based sorting signals.

30 f most surface proteins containing cell wall sorting signals.

31 e proteins with different types of cell wall sorting signals.

32 s putative transmembrane regions and protein-sorting signals.

33 ng of AP-3 to Arf but not to dileucine-based sorting signals.

34 motes cargo sorting by recognizing recycling sorting signals.

35 ng N-terminal signal peptides and C-terminal sorting signals.

36 at allow for recognition of a diverse set of sorting signals.

37 cells typically requires cytoplasmic domain sorting signals.

38 sensus sequences for kinases, and post-Golgi sorting signals.

39 s, ESMI(623)LL and QVVA(635)LL, as candidate sorting signals.

40 ses of specifically defined membrane protein sorting signals.

41 protein that is known to interact with such sorting signals.

42 tivated PAR1 and recognize discrete receptor sorting signals.

43 ided in part by a tyrosine-based basolateral sorting signal, (318)YNQV(321).

44 oxyl-terminal fragment contains a di-leucine sorting signal ((495)DDISLL(500)) and a ubiquitination s

45 Two sorting signals, a PXXP motif and a 658LL659 motif, are

46 physically engaging peptide-based endocytic sorting signals, a subset of clathrin-dependent transmem

47 A pathway by at least two different types of sorting signals: acidic cluster-dileucine motifs and cov

48 cagon is directed into granules by intrinsic sorting signals after initial processing to glicentin an

49 Sequences containing the M(3) sorting signal also conferred basolateral targeting to M

50 e NMR structure of (Ba)SrtA bound to a LPXTG sorting signal analog.

51 within peroxisomal APX as an overlapping pER sorting signal and a membrane peroxisome targeting signa

52 T) and the glycine (G) residues of its LPXTG sorting signal and catalyzes formation of an amide bond

53 rom the ER through direct interaction with a sorting signal and COPII.

54 f an amide bond between threonine (T) of the sorting signal and lysine (K) in the YPKN motif of anoth

55 19-amino acid peptide representing the M(3) sorting signal and surrounding sequence was analyzed via

56 ) glycoprotein contained an intrinsic apical sorting signal and that N- and O-linked glycans can act

57 The nature of the specific sorting signal and the mechanism through which it is int

58 quence (50 amino acid residues), a cell wall sorting signal and two repeat regions.

59 sortase A is involved in the binding of both sorting signals and calcium.

60 me signals are referred to as tyrosine-based sorting signals and conform to the NPXY or YXXO consensu

61 sortase enzymes cleave precursor proteins at sorting signals and involve the side chain amino groups

62 sortase enzymes cleave precursor proteins at sorting signals and involve the side-chain amino groups

63 oroplast targeting sequence or other obvious sorting signals and is not imported into isolated chloro

64 shed new light on the hierarchy of polarized sorting signals and on the mechanisms by which newly syn

65 ortases A and B recognize unique features of sorting signals and peptidoglycan substrates to deposit

66 encode sortase and pilin subunit genes with sorting signals and pilin motifs.

67 encode sortase and pilin subunit genes with sorting signals and pilin motifs.

68 ized by SrtC proteins through a pentapeptide sorting signal, and while previous studies have sought t

69 nforming to well-characterized leucine-based sorting signals, and a second containing a polyproline c

70 (Arf-1)-guanosine triphosphate (GTP), cargo sorting signals, and phosphoinositides.

71 ant for cellular function, including lateral sorting, signaling, and trafficking.

72 Nevertheless, sorting signals are located in the cytoplasmic domain si

73 e generally cytoplasmically disposed, apical sorting signals are not typically accessible to the cyto

74 paA pilin precursor, the pilin motif and the sorting signal, are together sufficient to promote the p

75 and Val(281) comprise a novel dihydrophobic sorting signal as mutations of either residue singly or

76 dase appears to have at least three distinct sorting signals as follows: the light chain (L-BEK) dire

77 m requiring surface proteins with C-terminal sorting signals as well as sortase enzymes.

78 ndoplasmic reticulum to the vacuole requires sorting signals as well as specific transport mechanisms

79 ite cysteine of sortase C and an LPNTA motif sorting signal at the C-terminal end of the BasI precurs

80 ion is necessary for it to bind a prohormone sorting signal at the trans-Golgi network (TGN) to facil

81 cell wall of Gram-positive bacteria, cleaves sorting signals at the LPXTG motif.

82 aining the LPKTGGS and LPKTGGRS sequences as sorting signals at the peptide C-terminus were effective

83 ace depends on the presence of a basolateral sorting signal (BaSS) in their cytoplasmic domain.

84 f the presence or absence of the basolateral sorting signal, because apical delivery was also inhibit

85 eaved peptides encompassing LPXTG motif-type sorting signals between the threonine (T) and the glycin

86 in precursors bearing C-terminal LPXTG motif sorting signals between the threonine and glycine residu

87 This specificity is tuned by the sorting signal binding conformation in which the first t

88 ably, a SpaB mutant that lacks the cell wall sorting signal but contains a critical lysine residue is

89 ow that SrtA adaptively recognizes the LPXTG sorting signal by closing and immobilizing an active sit

90 nd the glycine of its C-terminal LPXTG motif sorting signal by the pilin-specific sortase D.

91 in glucagon and GLP-1, but not GLP-2, act as sorting signals by efficiently directing a heterologous

92 me coat polymerization to the recognition of sorting signals by the BBSome.

93 Recognition of Ub as a sorting signal can occur at the trans-Golgi network and

94 g reaction in which a surface protein with a sorting signal containing a LPXTG motif is cleaved betwe

95 These results identify a novel sorting signal controlling the endocytic trafficking iti

96 To investigate whether this sorting signal could be involved in presentation of mela

97 N, mediated by tyrosine- and dileucine-based sorting signals, could be a mechanism for functional seg

98 due K139 or truncation of the SpaB cell wall-sorting signal (CWSS) abolished assembly of the SpaBC he

99 All basolateral sorting signals described to date reside in the cytoplas

100 Specific sorting signals direct transmembrane proteins to the com

101 yeast Ggas also function by binding peptide-sorting signals directly.

102 on microscopy, cell fractionation, cell wall sorting signal domain swapping, and Western blotting, we

103 ncompasses the YPK pilin motif and the LPXTG sorting signal, each of which is absolutely required for

104 , we discovered a highly conserved dileucine sorting signal encoded within the cytoplasmic tail that

105 escription of tyrosine-dependent cytoplasmic sorting signal for a type III membrane protein, have sug

106 led that BapA1 possesses a typical cell wall-sorting signal for cell surface-anchored proteins from G

107 accumulation: phosphorylation of p75NTR is a sorting signal for delayed sequestering of p75NTR-bound

108 iquitination of cargo proteins serves as the sorting signal for downstream trafficking and relies on

109 1 subunit at multiple sites is the lysosomal sorting signal for GABAB receptors.

110 ests the possibility that it may represent a sorting signal for glycosylated Gag.

111 of AQP-1, implying that ubiquitination is a sorting signal for its release.

112 tachment to membrane proteins can serve as a sorting signal for lysosomal delivery.

113 n intrinsically disordered linker encode the sorting signal for recruiting the transport factors for

114 Sorting signals for apically destined proteins are highl

115 ns and clathrin for endocytosis and serve as sorting signals for internalized cargo.

116 Thus, this receptor subunit may use distinct sorting signals for its constitutive regulation and liga

117 So far, no sorting signals for membrane trafficking have been ident

118 Acidic clusters act as sorting signals for packaging cargo into clathrin-coated

119 elopment of the cell, obviating the need for sorting signals for proper packaging of their constituen

120 e inner envelope protein CemA indicates that sorting signals for the thylakoid and envelope membranes

121 ith each other, with membranes, and with the sorting signals found on cargo molecules.

122 distinct subsets of tyrosine-based (YXXphi) sorting signals found within the cytoplasmic domains of

123 eceptor, provide the first example of such a sorting signal functioning in a proximal portion of the

124 While plant vacuolar sorting signals have been well described for two decades

125 dentification of an adaptor protein-specific sorting signal in a t-SNARE protein, and suggest that AP

126 the cellular protein sorting machinery, the sorting signal in HIV-1 Nef has not been identified.

127 mutant form of HA (C560Y) with a basolateral sorting signal in its cytoplasmic domain.

128 ebrate evolution, was shown to act also as a sorting signal in mouse gp75, confirming that its sortin

129 These data indicate that a dileucine-based sorting signal in Nef is utilized to address the cellula

130 the GPI modification serves as a primary Pd sorting signal in plant cells.

131 ce protein ubiquitination is the predominant sorting signal in receptor endocytosis, we investigated

132 suggest a model in which the tyrosine-based sorting signal in RID plays a role in RID's ability to d

133 These results identify an LV-based sorting signal in the ALP cytoplasmic domain that direct

134 basolateral surface by a tyrosine-dependent sorting signal in the APP cytoplasmic tail.

135 Mutagenesis studies identified a YYXXF sorting signal in the C-terminal cytosolic domain of Van

136 e normal interactions between the di-leucine sorting signal in the CD4 cytoplasmic domain and AP-2, b

137 Mutation of a methionine-based sorting signal in the cytoplasmic domain of either Sncp

138 ning a mutation that eliminated an endocytic sorting signal in the envelope glycoprotein, increasing

139 three critical features that comprise an ART sorting signal in the Mup1 N-terminal cytosolic tail: 1)

140 ed mutagenesis of the acidic dileucine-based sorting signal in the pigment cell-specific protein OCA2

141 We have identified a sorting signal in the yeast cell fusion protein Fus1p th

142 To identify the lipoprotein-sorting signals in Borrelia burgdorferi, we generated ch

143 Here, we aimed to determine the sorting signals in HIV-1 Nef that were responsible for i

144 and hierarchy of known and newly identified sorting signals in KOR1 and how they affect KOR1 transpo

145 both of which are well-described trafficking/sorting signals in the cellular secretory pathway.

146 in targeting native molecules bearing these sorting signals in the context of HLA-DM and the invaria

147 -receptor complex can occur without specific sorting signals in the cytoplasmic region of ObR.

148 n of furin to the TGN is largely mediated by sorting signals in the cytosolic tail of the protein, we

149 t to occur at the TGN through recognition of sorting signals in the cytosolic tails of the cargos by

150 in an Arf-dependent fashion and to recognize sorting signals in the cytosolic tails of the transmembr

151 suggest the existence of a diverse array of sorting signals in the GPCR superfamily that mediate sub

152 eral sorting motifs, which are homologous to sorting signals in the low density lipoprotein receptor,

153 ted to lysosomes by virtue of tyrosine-based sorting signals in their cytosolic tails.

154 apical surface of the cell, guided by apical sorting signals in their transmembrane or cytoplasmic do

155 recycling and bind conserved Asn-Pro-Xaa-Tyr-sorting signals in transmembrane cargos via an atypical

156 suggest a new role for peptide precursors as sorting signals in vesicular transport.

157 hin the prohormone sequence does not act as "sorting signal" in late secretion; instead, it seems to

158 Cleavable vacuolar sorting signals include the NH(2)-terminal propeptide (N

159 the absence of this cytoplasmic basolateral sorting signal, information within the extracellular lig

160 pigmentosa alleles that affect the rhodopsin sorting signal interfere with interactions between ARF4

161 ubstitution of sequences containing the M(3) sorting signal into the homologous regions of M(2) was s

162 The PY and YXXphi motifs are canonical sorting signals involved in trafficking.

163 ations reveal a novel mode of recognition of sorting signals involving the gamma/delta and sigma subu

164 We show that a functionally similar ART sorting signal is also required for the endocytosis of a

165 ic domain, a motif that resembles a cellular sorting signal is critical for activity.

166 e results indicate that the M(3) basolateral sorting signal is dominant over apical signals in M(2) a

167 tion studies, bidirectional best BLAST hits, sorting signals, known databases and visualizers which w

168 d active site His-Cys-Arg triad that joins a sorting signal located at the C terminus of their protei

169 plex to the endocytic pathway, directed by a sorting signal located in the cytoplasmic tail.

170 rted example of a sequence-specific vacuolar sorting signal located within an internal propeptide.

171 y for presentation of a Snx4-Atg20-dependent sorting signal located within its juxtamembrane region.

172 Although the identity of certain sorting signals located in Ii's cytoplasmic tail is know

173 han (658)LL(659) at overriding strong apical sorting signals located in the same molecule.

174 gon fragment, leading to the hypothesis that sorting signals may be present in multiple domains.

175 identified, there are few examples of linear sorting signals mediating directed export of membrane pr

176 ng of COPII-coated proteins to a hexapeptide sorting signal (MELADL) in Scap, the SREBP-escort protei

177 hese mutations did not share a single common sorting signal, nor were proteins sharing a putative cla

178 here that sortase C (SrtC) cleaves the LPNTA sorting signal of BasH and BasI, thereby targeting both

179 ires sortase A, which also cleaves the LPXTG sorting signal of BcpA between its threonine and glycine

180 sortases A and D require only the C-terminal sorting signal of BcpA for substrate cleavage.

181 Here, we show that the IPNTG sorting signal of BcpB, the minor pilin, is cleaved by s

182 sorting signal of H2M or the dileucine-based sorting signal of CD3gamma, confirming a role for clathr

183 C2 requires the VPPTG motif in the cell wall-sorting signal of Cpa.

184 Inactivation of the cell wall sorting signal of fap1 also eliminated long fimbrial for

185 his process involves the pilin motif and the sorting signal of FimA as well as corynebacterial sortas

186 lecules containing either the tyrosine-based sorting signal of H2M or the dileucine-based sorting sig

187 ic route, and that cleavage of the lysosomal sorting signal of Ii by CatS can occur there in mature D

188 The sorting signal of IsdC is cleaved between threonine and

189 n N-terminal signal sequence with a putative sorting signal of L(P/T/S)X(T/N/D)G and two unique signa

190 s pattern of distribution requires the LPXTG sorting signal of protein A as well as sortase A, the tr

191 evere form mutations occur in the C-terminal sorting signal of rhodopsin, VXPX-COOH.

192 requires the pilin motif and the C-terminal sorting signal of SpaA, and is proposed to occur by a me

193 1) protein, carrying the endosomal/lysosomal sorting signal of the LAMP-1, are capable of stimulating

194 of Pseudomonas aeruginosa exotoxin A, or the sorting signal of the lysosome-associated membrane prote

195 heat shock protein 70, calreticulin, or the sorting signal of the lysosome-associated membrane prote

196 After cleavage of the LPXTG sorting signal of the major pilin, BcpA, sortase D forms

197 her show that the sequence-specific vacuolar sorting signals of both proricin and pro2SA bind in vitr

198 ur interest in understanding the basolateral sorting signals of CD147 in prototypic Madin-Darby canin

199 ar cargo receptor AtELP to interact with the sorting signals of heterologous and endogenous plant vac

200 All identified basolateral sorting signals of integral membrane proteins are cytopl

201 Thus, unique attributes of the sorting signals of minor pilins provide Gram-positive ba

202 ics simulations of each SrtC enzyme with the sorting signals of RrgA, RrgB, and RrgC to determine the

203 us assembly upon alteration of the cell wall sorting signals of the accessory subunit proteins.

204 We identified three canonical tyrosine-based sorting signals of the type "YXXPhi" in the Cx43 C-termi

205 ddition of the mannose 6-phosphate lysosomal sorting signal on acid hydrolases, exhibited extensive v

206 Endocytic protein trafficking is directed by sorting signals on cargo molecules that are recognized b

207 Sorting signals on cargo proteins are recognized by coat

208 ange is associated with increased binding to sorting signals on the cytoplasmic tails of cargo molecu

209 rm and in three liganded forms (bound with a sorting signal or calcium or both).

210 eins does not appear to involve N-glycans as sorting signals, or lectin sorters.

211 dered to ordered transition upon binding the sorting signal, potentially facilitating recognition of

212 Similarly, both the kinase activity and the sorting signal present in PI4KIIalpha are necessary to r

213 The molecular basis of transpeptidation and sorting signal recognition are not well understood, beca

214 This study shows that coatomer couples sorting signal recognition to the GTP hydrolysis reactio

215 dense granule proteins, we demonstrate that sorting signals recognized by adaptor protein-3 are nece

216 These mGluR sorting signals represent novel plasma membrane axon/den

217 The M(3) sorting signal represents a novel basolateral targeting

218 e caused by mutations in nef, this Tyr-based sorting signal represents a novel target for future mode

219 LAT palmitoylation functions primarily as a sorting signal required for its PM transport.

220 -leucine sequence that is closely related to sorting signals required for AP-3 adaptor-dependent tran

221 dependent on a novel bipartite juxtamembrane sorting signal residing between Gln-692 and Thr-701.

222 cargo receptor complex and that the primary sorting signals residing in the B domain direct the bind

223 rminates upon sortase A cleavage of the BcpA sorting signal, resulting in a covalent bond between Bcp

224 To identify the sorting signal(s) that direct trafficking of NKCCs, we g

225 ytoplasmic domain replaced by a constitutive sorting signal (Sec22b SNARE) retains stress-responsive

226 We also demonstrate that the endosomal sorting signal, secretion, and the C-terminal part of Ii

227 It is inferred that, in vivo, sorting signal selection is under kinetic control, with

228 proteins to the lysosomes using a conserved sorting signal similar to that used by yeast and mammali

229 imary sequence conservation suggest that the sorting signal-stabilized oxyanion hole is a universal f

230 conserved threonine residue within the bound sorting signal substrate facilitates construction of the

231 covalent complex with an analog of its NPQTN sorting signal substrate, revealing the structural basis

232 Ahp1p contains a peroxisomal sorting signal, suggesting a peroxisomal localization.

233 e capable of interacting with tyrosine-based sorting signals, suggesting that they are functionally e

234 blocked the ability of Ub to serve as an MVB sorting signal, supporting the idea that both the Vps27-

235 Distinct cytoplasmic sorting signals target integral membrane proteins to lat

236 This Leucine-Valine (LV)-based sorting signal targeted chimeric proteins and native ALP

237 results suggest a model in which this novel sorting signal targets A(F-->A)-ALP into clathrin/AP-1 v

238 duces Env expression on infected cells and a sorting signal that directs Env expression to the basola

239 In many cases, ubiquitin functions as a sorting signal that facilitates trafficking of mammalian

240 These data define a novel sorting signal that is both necessary and sufficient for

241 We suggest that IXTPK comprises a novel sorting signal that is recognized and bound by exomer le

242 main functions as a transplantable endocytic sorting signal that is sufficient to re-route endocytose

243 equence of YRSL conforms to a tyrosine-based sorting signal that mediates clathrin-dependent endocyto

244 f Tac-furin trafficking, acting as an active sorting signal that mediates the selective sorting of Ta

245 athways is regulated by a latent basolateral sorting signal that restores EGF receptor polarity in cy

246 Ubiquitin (Ub) is a sorting signal that targets integral membrane proteins t

247 The concept of competing sets of sorting signals that act positively and negatively durin

248 fferent cellular compartments is mediated by sorting signals that are recognized by coat proteins inv

249 e polarized protein distributions depends on sorting signals that designate the trafficking route and

250 The sorting signals that direct proteins to the apical surfa

251 VGLUT1 thus contains multiple sorting signals that engage distinct trafficking mechani

252 irus (CaMV) MP contains three tyrosine-based sorting signals that interact with an Arabidopsis (Arabi

253 To identify potential sorting signals that mediate mAChR targeting, we examine

254 using an artificial reporter lacking natural sorting signals that recapitulates the energy dependence

255 leucine motif, one of two well-characterized sorting signals that target membrane proteins to clathri

256 ) have two chaplin domains and a C-terminal "sorting signal" that targets them for covalent attachmen

257 in the YCK3 gene identify the Yck3p vacuolar sorting signal-the tetrapeptide YDSI, a perfect fit to t

258 study suggest that SrtA recognizes the LPXTG sorting signal through a lock-in-key mechanism in contra

259 The similarity of the ALP sorting signal to mammalian dileucine sorting motifs, an

260 tidases join proteins bearing an appropriate sorting signal to strategically positioned amino groups

261 f a sequence containing the M(3) basolateral sorting signal to the cytoplasmic tail of the interleuki

262 tes with binding via cytoplasmically exposed sorting signals to either heterotetrameric adaptor AP-1

263 mic domain of TfR that function as recycling sorting signals to promote its transport from the recycl

264 The fusion of cell wall sorting signals to reporter proteins bearing N-terminal

265 anchors surface proteins bearing LPXTG motif sorting signals to the cell wall envelope of vegetative

266 IsdC precursor with a C-terminal NPQTN motif sorting signal, to the cell wall envelope.

267 We demonstrate interaction of the protein sorting signal Ubiquitin with the Vps9-CUE, a Ubiquitin

268 a known EGF receptor leucine-based lysosomal sorting signal used during ligand-induced trafficking, w

269 udy, an essential 14-amino acid (aa 335-348) sorting signal was defined on the cytoplasmic tail of As

270 to the previously identified tyrosine-based sorting signal, we find two more important residues for

271 the accuracy of predicting membrane protein sorting signals, we developed a general methodology for

272 To identify additional MVB sorting signals, we examined the previously described ub

273 s between dileucine-based and tyrosine-based sorting signals, we have categorized the motif through w

274 Multiple new prokaryotic C-terminal protein-sorting signals were found that reprise the tripartite a

275 Two distant topological sorting signals were required for efficient nuclear impo

276 complexes reveal the molecular basis of the sorting signal which depends on the residues at the -1 a

277 proteins (or "cargoes") generally acts as a sorting signal, which is recognized, captured, and deliv

278 s in a previously described 679-LL lysosomal sorting signal, which restrict ligand-dependent receptor

279 nown to contain a sequence-specific vacuolar sorting signal whose functionality depends on the presen

280 This unusual basolateral sorting signal will be useful in unraveling the speciali

281 eptidation mechanism, requiring a C-terminal sorting signal with a conserved LPXTG motif.

282 all by a mechanism requiring a COOH-terminal sorting signal with a conserved LPXTG motif.

283 all by a mechanism requiring a COOH-terminal sorting signal with a conserved LPXTG motif.

284 glycan by a mechanism requiring a C-terminal sorting signal with a LPXTG motif.

285 velope by a mechanism requiring a C-terminal sorting signal with an LPXTG motif.

286 velope by a mechanism requiring a C-terminal sorting signal with an LPXTG motif.

287 glycan by a mechanism requiring a C-terminal sorting signal with an LPXTG motif.

288 inantly vesicular carriers by interaction of sorting signals with adaptor proteins, but proteins in t

289 envelope by a mechanism requiring C-terminal sorting signals with an LPXTG motif.

290 ifferent, functionally redundant basolateral sorting signals with distinct amino acid requirements: o

291 of a phaseolin variant lacking its vacuolar sorting signal, with the aim to target the protein for s

292 Finally, we characterized the sorting signal within the context of a reconstructed Stv

293 reaction that joins a highly conserved LPXTG sorting signal within their polypeptide substrate to the

294 ough membranes, MIPS genes were analyzed for sorting signals within primary structures and upstream o

295 This is because redundant sorting signals within the cytosolic domain of the Droso

296 nction non-redundantly by recognizing unique sorting signals within their protein substrates.

297 ssed at an unexpected site downstream of the sorting signal yet still associates with the bacterial s

298 pable of interacting with the tyrosine-based sorting signal YQRL from TGN38.

299 uronal form of L1 carries the tyrosine-based sorting signal YRSLE, which is critical for sorting L1 t

300 osine residue forms part of a tyrosine-based sorting signal (Yxxphi).