ライフサイエンスコーパス: span

1 ve, affiliative interactions over their life span.

2 le mouse models, prolonging the healthy life span.

3 nescence, resulting in reduced residual life span.

4 OD1 levels and significant extension of life span.

5 rt morphologic phenotype throughout the life span.

6 n healthy subjects across a seven-decade age span.

7 osition in all brain regions across the life span.

8 e available to support the reproductive life span.

9 ce and developmental changes across the life span.

10 gh-risk HPV18 E7 to extend keratinocyte life span.

11 system jointly determines longevity and life span.

12 with two pore-loops and eight transmembrane spans.

13 avioral state change over short or long time spans.

14 ollected photographic capture-recapture data spanning 1,139 individual adult female Masai giraffes in

15 96 cognitively healthy individuals with ages spanning 100 years, as well as 67 adult individuals diag

16 cies exhibit homologous divergent haplotypes spanning 11 Mbp on chromosome 3.

17 wavelength range of 3.17-5.13 um (frequency span 1200 cm(-1), sampling point spacing 13-21 MHz), via

18 l results and analysis of SELEX publications spanning 13 years implicate the alkaline denaturation st

19 d mQTL was localized to a chromosomal region spanning 14 genes, including a previously defined steroi

20 727 peripheral and nervous system cell types spanning 17 mouse organs with body mass index (BMI) geno

21 27 recurrent non-reference unique insertions spanning 18,048,877 bp, some of which disrupt exons and

22 ous ancestry increased by an average of ~20% spanning 1940s-1990s in Mexican Americans.

23 isolation coincided with a migratory divide spanning 20 degrees of latitude.

24 s as they explore Wikipedia for over 5 hours spanning 21 days.

25 method and applied it to 500 cell lines(1,2) spanning 21 types of solid tumour.

26 in vivo a dataset of 91,534 toehold switches spanning 23 viral genomes and 906 human transcription fa

27 a large spatial variability with Cl contents spanning 3 orders of magnitude.

28 A total of 2434 admissions spanning 3 years pre- and 2 years postimplementation wer

29 ycling shifts along an Amazon-Andes transect spanning 3.5 km in elevation and 16 degrees C in mean an

30 Using an exceptional camera-trap dataset spanning 32 protected areas across southern Africa, we f

31 nodes and internodes of varying length that span 4-5 m and account for approximately 84% of harveste

32 ution (30 m) satellite imagery over a region spanning 4.7 x 10(6) km(2) in Alaska and northwestern Ca

33 labeling every voxel with a brain structure spanning 43 isocortical areas and their layers, 329 subc

34 Asian elephants from timber camps in Myanmar spanning 45 years (1970-2014).

35 Here, microcombs of more than two-octave span (450 nm to 2,008 nm) is demonstrated through chi((2

36 al pharmaceuticals/degradates were detected, spanning 5 orders of magnitude from 0.28 to 13 500 ng/L,

37 tomolar detection limits and a dynamic range spanning 5 orders of magnitude, comparable to photomulti

38 of BA curves differed by sex across the age span (50-90 years).

39 lteration, to an STIC, followed by a shorter span (6 years) for progression to an HGSC.

40 io between the two surfactants, Tween 20 and Span 60, in terms of entrapment efficiency and antioxida

41 atabase for tetrapod vertebrates in Uruguay (spanning 664 species) assembled to date, to identify hot

42 ing genes as well as 229,001 genomic regions spanning 72 species.

43 ons of infiltration in a panCNS tumor cohort spanning 80 subtypes.

44 Data collection spanned 98 separate nights of ad libitum sleep from five

45 , and to test to which extent these patterns span a continuum of neurofunctional alterations between

46 Third, our independent observations span a distance of more than 1,700 km, suggesting that o

47 nge of prior reported values themselves only span a factor of 4 (i.e., 0.1-0.4 Wm(-1) K(-1) ).

48 of such processes in several peatlands that span a gradient from hemiboreal to tropical ecozones and

49 Earth System Models (ESMs), and is found to span a large range even at 2 degrees C of global warming

50 The models span a range of TNBC subtypes and exhibit a diverse set

51 information in the dark states, they need to span a space with a dimensionality larger than one, so d

52 for a suite of biomass-burning phenols that span a wide range of air-water partitioning coefficients

53 Molecules are seen in environments that span a wide range of physical and chemical conditions an

54 M sensitivity of hippocampal CaMKII variants spanning a broad range of linker lengths and composition

55 ete resonances, generalizes both to a sample spanning a continuous period-ratio range, as well as to

56 we track individual coral colonies at sites spanning a gradient of local anthropogenic disturbance t

57 family with ~800 perfumery-related odorants spanning a range of chemical scaffolds and functional gr

58 Bioactivity of extracts from five wells spanning a range of DOC was tested using an in vitro mul

59 ngly, there must be a variety of chemistries-spanning a spectrum of rates and other features-to choos

60 samples belonging to 10 mammalian orders and spanning a temporal range from ~9.5 Ma to ~12 ky.

61 res of signal autocorrelation, and the other spanning a unimodal-transmodal axis and dominated by mea

62 spatial gradients of intrinsic dynamics, one spanning a ventromedial-dorsolateral axis and dominated

63 apid generation of block copolymer libraries spanning a wide range of compositions starting from a si

64 s across tropical to boreal forests in China spanning a wide range of latitudes (18 degrees 16' to 51

65 o strong to generate a family of models that spans a continuum from critical dynamics to asynchronous

66 eleration in one direction or the other that spans a remarkable 6 orders of magnitude.

67 ecular polymers is an intricate process that spans a wide range of length scales.

68 R), which positively affects health and life span across species, leads to metabolic reprogramming th

69 The most recent applications, now spanning across materials science, nanotechnology, biolo

70 anscripts are naturally occurring phenomenon spanning across the health-disease continuum, and likely

71 263 blocks fusion by binding an epitope that spans across E1 and E2 and locks the heterodimer togethe

72 Analysis of data from 469 sites spanning Alaska, USA, to Baja California, Mexico, and 37

73 tpiA with orthologous DNA from donor species spanning all domains of life, from humans to hyperthermo

74 In contrast, SOS LASSO uncovers a network spanning all four lobes of the brain.

75 north-south transect across European Russia, spanning all major forest types in the northern hemisphe

76 nimidyl sulfoxide, inter-protein cross-links spanning all MSC constituents were observed, including c

77 of fresh, forming skeletons from six species spanning all reef-forming coral morphologies: Branching,

78 lly growing systems are prevalent in nature, spanning all scales from biochemical reaction networks i

79 a global set of measurements from 112 sites spanning all terrestrial biomes.

80 e HSV-1 genome, repress numerous viral genes spanning all three kinetic classes, and suppress product

81 His career spanned almost five decades, resulting in more than 870

82 s 3-5-kb long kinetochore-bound regions that span an AT-rich core and are depleted of the canonical h

83 Viruses span an impressive size range, with genome length varyin

84 e to helical unwinding, the RNA triple helix spans an average of 12 base triples per turn.

85 Combined, these facilities span and are degrading 886 PAs, 749 KBAs and 40 distinct

86 rNMPs on mtDNA stability over the mouse life span and found that the mtDNA rNMP content increased dur

87 However, strategies to extend health span and life span require understanding of interindivid

88 may guide strategies to maintain its health span and provide a permissive milieu for neurogenesis.

89 tion has been associated with increased life span and reduced aging-related disorders and reduces fib

90 plicate novel candidate genes affecting life span and suggest that variation for life span may be mai

91 ost-replication remethylation rate constants span approximately two orders of magnitude, with half-li

92 n-recombining region between the X and the Y spans approximately 17.5 Mb on the X chromosome.

93 rsely, the favorable effects of CR on health span are mitigated by elevating ambient temperature to t

94 cycles after accounting for anovulatory time spans-are at lower risk for these inflammation-related c

95 e assessed for SRNI during at least 5 visits spanning at least 2.5 years in 2013-2017.

96 ecialists, with some generalist species that span both biomes.

97 exhibit widespread, late patterning defects spanning both axes.

98 ht current applications with select examples spanning both materials and life sciences.

99 f the G protein-coupling seven-transmembrane-spanning bundle.

100 ld upon our previous report of a beta-strand spanned by residues 30-42, which arranges into an antipa

101 More interestingly, a state-space spanned by such constellations shows that only correct o

102 in proteolytically cleaved form, as membrane-spanning C-terminal fragments of the proteins.

103 came from 3 neuroimaging samples (N = 2423), spanning childhood or adolescence to middle age, with pr

104 ends both replicative and chronological life span (CLS).

105 photosynthetic rates, and shorter leaf life span compared to non-wetland plants.

106 greatest risk of death and decrease in life span compared with other combinations.

107 nce that dynorphin-expressing neurons, which span cytoarchitecturally distinct domains of the lPBN, a

108 unopathogenesis of rheumatoid arthritis (RA) spans decades, beginning with the production of autoanti

109 productive Ag encounter and have finite life spans dependent on survival signals propagated by the BC

110 y of EPL against four phytobacterial species spanning different classes within the Gram-negative phyl

111 interaction profiles of 28 different GPCRs, spanning different levels of classification and conforma

112 The vineyards span distances which range from several hundred meters t

113 Rare inherited forms of CKD frequently span diverse phenotypes, reflecting genetic phenomena in

114 ocated in the loop region of CFTR's membrane-spanning domain.

115 challenges, both regulatory and logistical, spanning donor eligibility, donor recruitment, collectio

116 In recent decades, life expectancy and life span equality have occasionally moved in opposite direct

117 framework to study life expectancy and life span equality over time, relying on concepts about the p

118 elationship between life expectancy and life span equality with reliable data from the Human Mortalit

119 h likely contributes to the health- and life-span extending effect of IIS pathway downregulation.

120 knockout of PTPN14 rescued keratinocyte life span extension in the presence of the PTPN14 binding-def

121 Axons span extreme distances and are subject to significant st

122 at undergo internal motions with time scales spanning femtoseconds to milliseconds.

123 man genomic variation developed from samples spanning five continents.

124 ased on a global dataset with flower biomass spanning five orders of magnitude, we show that heavier

125 mong a panel of 108 maize (Zea mays) samples spanning five tissues from eight inbred parents and 12 h

126 In total, this corpus spans five US cities and consists of 19.8 h of audio mat

127 datrae) on hundreds of amphibian populations spanning four native species.

128 ssion, with each glacial-interglacial period spanning four or five cycles of ~20,000 years.

129 l modification with pleiotropic effects that span from regulation of transcription to metabolic proce

130 ng interest owing to its relevance in fields spanning from biomineralization to the rational design o

131 udy of schizophrenia with 2,137 observations spanning from childhood to 20 years after first admissio

132 he perspective of engineered in vitro models spanning from conventional planar, static monolayer cult

133 ncover dozens of kinase-disease associations spanning from genetic disorders to complex diseases, inc

134 lements is an important goal for many fields spanning from genomics to antisense therapy and diagnost

135 ecent microplasma applications are examined, spanning from high-throughput, printing-technology-compa

136 Diverse assays spanning from immunohistochemistry (IHC), to microarrays

137 In joint performances spanning from jazz improvisation to soccer, expert perfo

138 a wide band of the electromagnetic spectrum, spanning from microwaves to infrared light, and is a par

139 The final list of 20 issues includes topics spanning from the political (the regulation of genomic d

140 mall molecules that are included in the EML, spanning from their origin, to their stereochemistry and

141 the importance of establishing open networks spanning geographical boundaries.

142 actors; and then proposes a set of solutions spanning health system innovation, policy, and research

143 helix organisation, composed of one membrane-spanning helix (TM) and another that penetrates the inne

144 we show that KCNE3 tucks its single-membrane-spanning helix against KCNQ1, at a location that appears

145 light-matter interactions, with applications spanning high-efficiency on-chip lasing, frequency comb

146 millisecond time scale dynamic pathway that spans HNH from the region interfacing the adjacent RuvC

147 d gradient boosting models and register data spanning hospitalizations, drug prescriptions and contac

148 ical spectra at high resolution over a broad span in almost complete darkness.

149 ronic high-Pi diet which also shortened life span in the BK/BK;kl/kl mice.

150 orie restriction and rapamycin extended life span in virtually all genotypes but through different ge

151 veals 35 million deletions (~ 470,000 unique spans) in skeletal muscle from 22 individuals with and 1

152 on and function depend on the seven-membrane-spanning inactive rhomboid-like proteins 1 and 2 (iRhom1

153 Additionally, SpAn infers the emergent network biology of tumor microe

154 As a result, species with ranges that span international borders-which include 53.8% of terres

155 ct, we provide a set of recommendations that span investments in sectors that have sustained direct a

156 cant contributions that appeared in the time span January 2015-August 2019, describing the sustainabl

157 g surface, which is centered on a short loop spanning K61 to I72 and flanked by longer alpha-helices

158 datasets delineate gene expression profiles spanning key differentiation events in human thymopoiesi

159 te matter, intracortical, subpial and cortex-spanning lesions, respectively).

160 ching manifolds, which constitute strategies spanning life in different habitats and hosts.

161 The analysis involved 14 countries spanning low-income to high-income settings, and cost-ef

162 ir eyes respond to the changes in brightness spanning many orders of magnitude, associated with their

163 Reported data span March 21 to June 16, 2020 for hospitalized pregnant

164 ife span and suggest that variation for life span may be maintained by variable allelic effects in he

165 ing assembly to minimize misfolding of multi-spanning membrane proteins and maintain cellular protein

166 ntrast, very little is known about how multi-spanning membrane proteins with several TMDs are assembl

167 ex show reduced biogenesis of numerous multi-spanning membrane proteins.

168 systems, involving siderophores and membrane-spanning metal importers, and the biological specificity

169 ial taperings of respiratory depth typically spanning minutes at a time, are more common in males.

170 Research Database Issue contains 148 papers spanning molecular biology.

171 hole genome sequences representing 21 orders spanning more than 500 million years of arthropod evolut

172 have evaded characterization despite efforts spanning more than half a century.

173 This complex spanned most of central Europe and exhibits demographic

174 Therefore, disease signals likely span multiple biological domains, including genes, prote

175 gions of concordant differential methylation spanning multiple CpG sites (differentially methylated r

176 investigate a wide range of dynamical events spanning multiple spatial and temporal scales.

177 e resurrected historic propagules of Daphnia spanning multiple species and lakes in Wisconsin followi

178 ch interactions are inherently multivariate, spanning multiple time and size scales, cell types, and

179 The exposome spans multiple domains from population to molecular leve

180 finely resolved stratigraphic sequence that spans nearly 17,000 years.

181 2416/TENM2 in lung), and expression of genes spanning nicotine dependence-associated variants is enri

182 flanking regions or the entire genomic block spanning Nppa-Nppb, respectively, were deleted from the

183 sual cortex, and higher-order visual regions spanning occipital and temporal cortex.

184 ide by unit and by drug for an 8-year period spanning October 2010 to October 2018.

185 rption of over 90% in the visible wavelength span of 400-750 nm.

186 ate middle age (8 months apart, similar to a span of 5-6 years in humans).

187 sed this model to project the effective life span of antibiotics and the number of gonorrhea cases ex

188 s strategy could increase the effective life span of antibiotics by 0.94 years, which is equivalent t

189 enation free energies and shows that a large span of aromatic properties, from highly antiaromatic to

190 pared with Atg7 (Delta/Delta) mice, the life span of Atg7 (Delta/Delta) p53 (Delta/Delta) mice was ex

191 this is not sufficient to calibrate the full span of detection channels, ranging from yttrium (89 amu

192 exotic and six native Osmia species over the span of fifteen years (2003-2017) to estimate abundance

193 pH reduction in their drinking water over a span of more than 20 years, the City of Newark, New Jers

194 ty as no difference was observed in the life span of mosquitoes with different genotypes (chi(2) = 1.

195 and diamine/diol, respectively, in a shorter span of reaction time.

196 inate the timing of germination and the life span of seedbanks.

197 A new study shows that the pregrasp span of the hand of an individual with such a lesion rem

198 pinal cord, and a significantly shorter life-span of the mice.

199 ls, HCMV must subvert the natural short life-span of these blood cells by inducing a distinct activat

200 Gene therapy increased the life span of treated animals, rescued the lethal neurodegener

201 alternative strategies on the effective life spans of antibiotics and the overall burden of gonorrhea

202 ology to calcium imaging of entire dendritic spans of neurons as well as neural ensembles within mult

203 aperiodic fluctuations in species abundance spanning orders of magnitude in scale, which have vast e

204 h within species and across nematode species spanning over 100 million years of evolution.

205 A typical hand muscle spans over 3 degrees of freedom (DOF), wrapping over com

206 the chemical sciences(1), with applications spanning pharmaceuticals, agrochemicals and functional m

207 Here, we report a comprehensive analysis spanning prediction tasks from ulcerative colitis, atopi

208 We show that SpAn predicts the 5-year risk of CRC recurrence with a m

209 Research suggests that neural activity spanning prefrontal, parietal, temporal, and visual area

210 s of ~10,000 testicular cells from four boys spanning puberty and compared them to those of infants a

211 RNA-seq data based on back-splicing junction-spanning reads, computational tools to identify critical

212 r, strategies to extend health span and life span require understanding of interindividual difference

213 at women who have a longer reproductive life span-roughly determined as the period from menarche to m

214 surveillance and provided blood at intervals spanning RTPCR-confirmed transmission.

215 interferon-gamma-based assays with peptides spanning SARS-CoV-2 except ORF1.

216 mectic river networks correlated over system spanning scales.

217 A new study of African fossils spanning seven million years shows that ancient large-he

218 th severe chronic inflammatory diseases that span several organ systems(3-6).

219 Prominent actin cables, spanning several cells, are abundant both in cultured ag

220 ctral measures to quantify this condensation spanning several dynamical systems.

221 ojecting serotonergic neuron (the CSDn) that spans several olfactory regions.

222 omes of eukaryotic cells can be dramatic and spans several orders of magnitude.

223 the most widely used imaging modalities that spans several scientific and technological fields.

224 nhibited quiescence, which explains the life span shortening.

225 Within a relatively short time span, social media have transformed the way humans inter

226 inding at this site blocks the transmembrane-spanning sodium ion translocation pathway, providing a m

227 late more primitive transcriptional programs spanning stem-like to regenerative pulmonary epithelial

228 n = 938) carriers of 0.8-2.5 Mb duplications spanning STS, and non-carrier male (n = 192, 826) and fe

229 oduction under natural illuminances that can span ten orders of magnitude.

230 uncovered a network of RNA-RNA interactions spanning tens of thousands of nucleotides.

231 a novel structure, with seven transmembrane spans that form a large water-filled membrane chamber wh

232 tive plant eudicot and monocot families that span the angiosperm phylogeny.

233 in a subset of cholecystokinin neurons which span the area postrema and the nucleus of the tractus so

234 ees C at the Piccard hydrothermal field that span the canonical 122 degrees C limit to life, and thus

235 s form dynamic intracellular networks, which span the entire cytoplasm and provide mechanical strengt

236 alibration sets have large sample numbers to span the expected sample matrix variations.

237 We detected homologous segments that span the first betaalphabeta motif of both lineages, inc

238 ly on inference from short reads that do not span the full length of the isoform.

239 nerate broadband power-law spectra, that may span the gap between petawatt-class infrared laser facil

240 ntial mechanical vulnerability of axons that span the gray-white tissue interface.

241 Continuous water columns that span the indentation were determined to be on-path trans

242 Bi(1-x)In(x)AgCl(6) HDP solid solutions that span the indirect to direct band-gap modification which

243 esolved bottom water delta(13)C records that span the interglacials of the last 0.5 million years to

244 anes can organize into patterned arrays that span the membrane's lateral size.

245 ore complexes are multiprotein channels that span the nuclear envelope, which connects the nucleus to

246 tral hydrophobic tunnel sufficiently long to span the periplasm.

247 novel targets and therapeutic molecules and span the range from primitive model organisms such as Sa

248 d operates with irradiation wavelengths that span the ultraviolet to the red/near-infrared.

249 Dendritic arbors spanned the length and/or width of vLGN and were often a

250 Brain regions sensitive to daylength spanned the socioemotional brain circuits, where MOR ava

251 Using a 32-microelectrode array spanning the depth of cortex, electrophysiological recor

252 of absolute Raman scattering cross sections spanning the frequency range of 500-4000 cm(-1) for cycl

253 boundary response, and a further enhancement spanning the full extent of the figure region that is dr

254 of C. elegans Taking advantage of long reads spanning the full length of mRNA transcripts, we provide

255 of the series of interacting protein rings, spanning the inner and outer membranes to form the ~45-5

256 cords of anthropogenic atmospheric lead (Pb) spanning the last 4000 years, an effective indirect prox

257 compilation of subfossil chironomid records spanning the last glacial-interglacial transition (~15,0

258 -resolved and absolutely dated marine record spanning the last millennium, and the Paleoclimate Model

259 residues lysine 274 to glutamate 380 of tau, spanning the last residue of the R1 repeat, the whole of

260 ort evidence for long-term human occupation, spanning the last ~80 thousand years, at the site of Dha

261 sis revealed twenty-two polymorphic variants spanning the length of this gene, including two nonsynon

262 e relationship between load and contact area spanning the limits of non-adhesive normal contact to ad

263 identified in 3% to 5% of bacterial genomes, spanning the majority of phyla.

264 the sequence of near-coast geological events spanning the Northeast Atlantic inception of an Ice Age.

265 ct interaction of E2A-PBX1, through a region spanning the PBX1 homeodomain, with RUNX1.

266 loops of VP2 and the BC and HI loops of VP3 spanning the region around the 3-fold axis.

267 ase 3 Last Millennium climate model ensemble spanning the same time period, to examine the influence

268 of gene dosage variation triggered by a CNV spanning the SEC10 gene on SEC10 expression at both the

269 evelopmental time points (P10, P15, and P20) spanning the tonotopic critical period.

270 and content mixing stimulated by a fragment spanning the two C(2) domains of synaptotagmin-1, or by

271 ins of synaptotagmin-1, or by a peptide that spans the C-terminal half of the synaptobrevin SNARE mot

272 ent of a multilevel mechanistic account that spans the cognitive, systems, network, and even cellular

273 One DNA duplex spans the diameter of the hexamer and passes over the ur

274 pansion in a class of dispersal models which spans the extremes of local (effectively short-ranged) a

275 Our structure shows that COMPASS spans the face of the nucleosome, recognizing ubiquitin

276 idge that includes an actin-like protein and spans the gamma-TuRC lumen.

277 tion mechanism involving an active site that spans the interface between two dimers, sandwiching the

278 e stratigraphy at Bacho Kiro Cave, Bulgaria, spans the Middle to Upper Palaeolithic transition, inclu

279 The LINC complex spans the nuclear envelope and mediates nuclear mechanot

280 rminal regulatory domain (CTD); a carotenoid spans the two domains.

281 Calorie restriction (CR) enhances health span (the length of time that an organism remains health

282 displacement that lasted several months and spanned thousands of kilometres.

283 These approaches span three domains: (a) social, economic, and environmen

284 The finds span three separate archaeological deposits, suggesting

285 dult mice causes liver damage, shortens life span to 3 mo due to neurodegeneration, and is lethal upo

286 ale and are weak, with vein density, minimum spanning tree ratio, and circularity ratio linked to mec

287 ircularity ratios, vein density, and minimum spanning tree ratios.

288 lasma-driven undulator radiation with octave-spanning tuneability at discrete wavelengths reaching fr

289 MS platforms among 13 different laboratories spanning two continents.

290 of species) with only five functional groups spanning two essential trade-offs-the growth-survival an

291 We generated 268 epigenomic datasets spanning two state transitions-from normal prostate epit

292 Interventions across the developmental span, varying risk levels, and service contexts (e.g.,co

293 hyperpolarization is sensed by the membrane-spanning voltage sensor domain (VSD), and the cNMP-depen

294 12 conifers and three oaks along a transect spanning warm dry foothills (500 m above sea level) to c

295 s systemic heparin group, median filter life span was 47 hours (interquartile range [IQR], 19-70 hour

296 rse species will respond to weather extremes spanning weeks to months.

297 of fingolimod on twitching behavior and life span were also demonstrated.

298 ding S. aureus, yet they have a limited life span with replacement by bone marrow derived monocytes.

299 ing CD19-Cre, female mice have a normal life span without obvious illness.

300 ncy virus (HIV) to live a near expected life span, without progressing to AIDS or transmitting HIV to