ライフサイエンスコーパス: sparing

1 ddle-retinal opacification with periarterial sparing.

2 -mediated immunity, and promote antigen dose sparing.

3 tural productivity appears to be mainly land-sparing.

4 soluble drug, representing a seven-fold dose sparing.

5 habitat are protected, consistent with land sparing.

6 f the laser therapy on white and gray matter sparing.

7 pregnancy outcomes interventions need to be sparing.

8 bles likely to influence the success of land sparing.

9 id not translate to significant in vivo dose sparing.

10 typical, limbic-predominant, or hippocampal-sparing.

11 g/h and results in a large intravenous fluid sparing.

12 is correlated to STGD1, later AO, and foveal sparing.

13 cal and multilobar, possibly with subpleural sparing.

14 stopathologic features was 100% with macular sparing (7/7; 95% CI, 47%-100%), optic nerve visibility

15 to those of penetrating keratoplasty, while sparing a healthy endothelial graft.

16 to HEPAVIR and HIV cirrhosis criteria while sparing a significant number of EGD, thus improving reso

17 to HEPAVIR and HIV cirrhosis criteria while sparing a significant number of EGDs, thus improving res

18 Instead, it may have insulin-sparing action, which seems to reduce the need for insul

19 solone, suggesting the potential for steroid sparing activity.

20 trongest evidence to date of an intellectual sparing advantage with PRT in the treatment of pediatric

21 The remarkable normal tissue sparing afforded by FLASH may someday provide heretofore

22 for improving functional recovery and tissue sparing after SCI.

23 atment with prednisone and/or glucocorticoid-sparing agents.

24 ommunity simulations, we also show that land-sparing agriculture conserves greater functional diversi

25 ctivated poliovirus vaccine (fIPV) is a dose-sparing alternative to the intramuscular full dose.

26 ase inhibitor-sparing and protease inhibitor-sparing alternative to three-drug regimens that reduces

27 GA lesion enlargement due to possible foveal sparing, alternative assessments are being explored to c

28 es that prevent respiratory depression while sparing analgesia.

29 A major component ERAS pathways is opioid-sparing analgesia; however, the effect on postoperative

30 as to outline important components of opioid-sparing analgesic regimens.

31 l acetaminophen and other potentially opioid-sparing analgesics, on the incidence of postoperative de

32 ogic features with time, and relative foveal sparing and also has a peripheral retinal location in L-

33 t highest risk of death may be an antibiotic-sparing and cost-effective, or even cost-saving, strateg

34 arch into the contrasting strategies of land sparing and land sharing has suggested that land sparing

35 Subpleural sparing and pleural effusion were seen approximately in

36 Subpleural sparing and pleural effusion were seen in approximately

37 a nucleoside reverse transcriptase inhibitor-sparing and protease inhibitor-sparing alternative to th

38 Hippocampal-sparing and the no atrophy group showed less aggressive

39 on-memory cognitive functions in hippocampal-sparing and the no atrophy group.

40 NSAIDs have analgesic, opioid-sparing, and anti-inflammatory effects.

41 clude therapies that are oral, anthracycline sparing, and deliverable in resource-limited settings.

42 combination of intracellular delivery, dose sparing, and extended release in treating chronic bacter

43 enhanced immune responses, was antigen dose-sparing, and induced a T helper 1 (Th1) response.

44 acrophages enhances NG2 cell responses, axon sparing, and sprouting of serotonergic axons.

45 e physiological functions such as anesthetic sparing, and working memory enhancement.

46 T to identify potential commensal microbiota-sparing antibiotics.

47 le antinociceptive effects, and offer opioid-sparing antinociceptive effects in myriad preclinical in

48 vivo modeling system, clinically used valve-sparing aortic root replacement conduit configurations h

49 configurations are clinically used for valve-sparing aortic root replacement, some specifically focus

50 tion identified as good candidates, a tissue-sparing approach may result in fewer complications.

51 rnal mammary artery graft is done by sternal-sparing approaches or by robotic-assisted, endoscopic su

52 usly published cases confirmed peripapillary sparing as consistent feature on fundus autofluorescence

53 hila peripheral nervous system exhibit organ sparing at the level of arbor growth: Under nutrient str

54 more diffuse lesions with only periarterial sparing at the most severe end of the spectrum.

55 tal layer 13 and other tectal related areas, sparing auditory, and trigeminal ones.

56 y developed a bronchial-arterial-circulation-sparing (BACS) lung preservation approach and tested whe

57 bearing large-animal model while selectively sparing blood vessels and collagen.

58 tivation of ML impaired face detection while sparing body and object detection.

59 st considerable benefit in terms of toxicity sparing, but this has only recently been confirmed by su

60 ibited CGG RAN translation, while relatively sparing canonical translation.

61 ced viability of CD138(+) plasma cells while sparing CD138(-) cells derived from bone marrows of newl

62 rons in the RMTg significantly while largely sparing cells in neighboring regions.

63 inhibitory tone to iBAT represents an energy-sparing circuit that integrates environmental food cues

64 ing and land sharing has suggested that land sparing-combining high-yield agriculture with the protec

65 The identification of antibiotics sparing commensal bacteria remains an ongoing challenge.

66 ptive and maladaptive neuroplasticity: i.e., sparing contextual memory, but affecting working memory

67 eration and resistance to apoptosis in vitro sparing control cells.

68 Primary outcome was corticosteroid-sparing control of inflammation at 5 and 6 months.

69 steroids were able to achieve corticosteroid-sparing control of inflammation by 6 months.

70 ne resolved, and 88% achieved corticosteroid-sparing control of inflammation.

71 atory therapies for achieving corticosteroid-sparing control of noninfectious uveitis, but there is u

72 cannot be synthesized in single-phase form, sparing costly and time-consuming synthesis efforts.

73 mproved clinical outcome, and postulate that sparing desynchronizing regions may further be beneficia

74 ivates enhancer regenerative activity, while sparing developmental activity.

75 Here we report the development of a brain-sparing DT, termed BRAINSPAReDT, for tissue-specific gen

76 cer; pylorus-preserving approach of pancreas-sparing duodenectomy (PSD) is preferred.

77 Although the tissue-sparing effect (TSE) in response to non-uniform radiatio

78 ds, thus allowing for a major corticosteroid-sparing effect and a halved number of adverse events rel

79 PC nanogel as a vaccine adjuvant had a dose-sparing effect and significantly enhanced the long-lasti

80 The safety profile and steroid-sparing effect favoured the combination of prednisone pl

81 in previously BCG-vaccinated mice had a dose-sparing effect for subsequent vaccination with fusion pr

82 study shows, for the first time, the steroid sparing effect of cetirizine and montelukast in addition

83 ted visual acuity (BCVA), and corticosteroid-sparing effect were also analyzed.

84 char saved 91 tonnes of CO(2)eq through land sparing effect, 13 tonnes of CO(2)eq sequestered in the

85 1070 and Darbepoetin alfa resulted in an EPO-sparing effect.

86 at the endocannabinoid system promote opioid-sparing effects in the treatment of pain reflects an imp

87 gricultural expansion, thus eroding the land-sparing effects of increasing productivity.

88 hat promise to provide better corticosteroid sparing effects than standard treatments and can even in

89 rat osteoporosis model demonstrates its bone-sparing efficacy.

90 and thromboxane A2 receptor (TP) (11) while sparing EP2, EP3, and prostaglandin I2 receptors (IPs);

91 ablated ErbB-hyperactive cancer cells while sparing ErbB-normal cells.

92 d be ideal for treating these pathologies by sparing essential JAK2 functions.

93 tion only of slow-twitch muscles and largely sparing fast-twitch muscles.

94 The preceding RRD was macula-sparing for 6 of 9 patients; all of them involved the ri

95 The benefits of land sparing for both biodiversity and carbon storage suggest

96 of which was identified as potentially land-sparing for solar energy development.

97 geographic atrophy (GA) and residual foveal sparing (FS), and to identify the minimum FS and maximum

98 inactive heterodimers of BTB proteins while sparing functional homodimers.

99 r unhindered reading in patients with foveal-sparing GA.

100 onsuming fatty acid metabolism toward oxygen-sparing glycolysis and glucose oxidation and to increase

101 limited toxicity to normal CXCR4(+) tissues, sparing haematopoietic stem cells and progenitors.

102 uced stronger antibody responses than a dose-sparing half-dose boost, although the magnitude of T cel

103 nic B-lymphocytic leukemia tumor cells while sparing healthy B cells.

104 the specific targeting of cancer cells while sparing healthy cells.

105 eukemia cell lines and patient samples while sparing healthy cells.

106 ic target for eradicating cancer cells while sparing healthy cells.

107 and preferential DNA delivery to HCC cells, sparing healthy hepatocytes.

108 ignificantly reduced neovascular tufts while sparing healthy retinal vessels, thereby demonstrating t

109 ol drug activation at specific tissues while sparing healthy tissues remains a major challenge.

110 t only degraded elastin in vasculature while sparing healthy tissues.

111 therapeutic activity at the site of disease, sparing healthy tissues.

112 Nonanatomical tissue-sparing hepatectomies are associated with worse DFS in p

113 eir photothermally heating capacity, thereby sparing hepatocyte from thermal damage induced by the la

114 7 and iNKT17 cell function while selectively sparing IL-22(+) subsets.

115 y more than 90% and 60%, respectively, while sparing immune and cardiac functions.

116 irus replication while maintaining allograft-sparing immune suppression.

117 gic testing for CRMP5 IgG to expedite vision-sparing immunosuppressant therapy and a targeted search

118 ninfectious uveitis requiring corticosteroid-sparing immunosuppressive therapy from 9 referral eye ce

119 nt inflammation necessitating corticosteroid-sparing immunosuppressive therapy.

120 omotor recovery and spinal cord white matter sparing in Bmal1(-/-) mice after T9 contusive spinal cor

121 Medial temporal sparing in non-amnestic Alzheimer's disease may thus be

122 Notably, the functional sparing in SOD1-G93A mice at 12 weeks was paralleled by

123 ne, a functional group that is conspicuously sparing in the sequences of mussel proteins, exhibit rev

124 ansion (Jevons paradox) or contraction (land-sparing) in 10 Latin American countries over 1990-2010.

125 ctions of a simple, more tolerable, and dose-sparing intradermal administration followed by electropo

126 potential advantages over ferredoxin by (i) sparing iron for abundant iron-sulfur proteins essential

127 In ARB patients, peripapillary sparing is a consistent feature on fundus autofluorescen

128 p53-deficient cells with camptothecin while sparing isogenic p53-positive cells.

129 trating agriculture on existing farmland and sparing land for nature is well-established, but the spa

130 SCC for reduced radiation dose as a means of sparing late sequelae.

131 ) is a transcatheter mimic of surgical chord-sparing leaflet resection.

132 ted controls and those with selective, fiber-sparing lesions of either the OFC or VLPFC.

133 To test this premise, the effects of axon-sparing lesions of the RMTg were assessed on LHb-induced

134 Here, we show that axon-sparing lesions of the rostromedial tegmentum attenuate

135 n of effective and safe dosage is the key to sparing local therapy.

136 4020, which is a noncovalent, wild-type EGFR sparing, macrocyclic TKI.

137 e simple, fast, and both solvent- and sample-sparing, making it an attractive tool for drug developme

138 on (IBBR) after receiving either: (1) nipple-sparing mastectomy (NSM) or (2) simple mastectomy with s

139 enes who are eligible for mastectomy, nipple-sparing mastectomy is a reasonable approach.

140 onserving surgery and nipple-sparing or skin-sparing mastectomy with immediate breast reconstruction,

141 reconstruction after nipple-sparing or skin-sparing mastectomy with planned radiotherapy should be a

142 n, recommended the 1-drop strategy as a dose-sparing measure if mOPV2 supplies deteriorate further.

143 nd safety of mechanical adjuvants in mucosal-sparing, mechanical endoscopic dacryocystorhinostomy (MM

144 e media analysis provides an effective, skin-sparing method for preclinical assessment of novel drug

145 There is little evidence that CNI-sparing/minimization strategies, steroid minimization or

146 limbic-predominant (n = 33), or hippocampal-sparing (n = 35) by using the Scheltens' scale for media

147 Selective inhibition of Na(V)1.6, while sparing Na(V)1.1, is anticipated to provide a more effec

148 ly and epicardially though fat while acutely sparing nearby the coronary arteries.

149 esents the leading cause of death worldwide, sparing no nation, ethnicity, or economic stratum.

150 thesia blocks consciousness and memory while sparing non-conscious brain activities.

151 oss of exhausted T cells within tumors while sparing nonmalignant tissues.

152 Effects were selective, sparing nontaste papillae.

153 e and time-dependent apoptosis in CLL cells, sparing normal B lymphocytes.

154 iminate pathological neovascular tufts while sparing normal blood vessels are needed.

155 new approach to effectively kill ERPC cells sparing normal cells and suggest that development of a l

156 I438K expression is tolerated in adult mice, sparing normal cells but allowing for an enhanced p53 re

157 ells and/or virally infected cells, although sparing normal cells, and has been implicated in the pat

158 c effect in PIK3CA-mutant cancer cells while sparing normal cells.

159 RAILR2/DR5 in a wide range of cancers, while sparing normal cells.

160 ectively trigger cancer cell apoptosis while sparing normal cells.

161 xtensive apoptosis in carcinoma cells, while sparing normal epithelial cells.

162 ated selective eradication of R/R LSCs while sparing normal hematopoietic stem/progenitor cells.

163 ently target all GBM molecular classes while sparing normal human astrocytes.

164 vely replicate and destroy tumor cells while sparing normal ones.

165 nd selectively targeted leukemia cells while sparing normal progenitor cells.

166 Cancer-specific targeting sparing normal tissues would significantly enhance cance

167 ng acquired resistance more difficult, while sparing normal tissues.

168 potential for treating micrometastases while sparing normal tissues.

169 better target dose distribution and similar sparing of critical structures.

170 s a superior strategy to address DSA via the sparing of CTLA-4 and more potent targeting of Tfh cells

171 fields, the hilus of the dentate gyrus (with sparing of granule cells), and the entorhinal cortex.

172 l GABAergic projection neurons with relative sparing of interneurons accompanied with astrogliosis.

173 rHD1, but not in rHD7, suggesting a relative sparing of interneurons over projection neurons in the s

174 eation with capacity for fat penetration and sparing of nearby coronary arteries because of cooling e

175 delivery of tumoricidal radiation doses with sparing of nearby organs at risk.

176 were safe and efficacious with demonstrable sparing of nerves and venous tissue.

177 ed to highly accurate targeting of tumor and sparing of normal tissue; however, in the pelvic region

178 etabolism on (18)F-FDG PET, whereas relative sparing of posterior cingulate metabolism compared with

179 a 'reversed' temporal gradient with relative sparing of recent memories.

180 e found commonly in the macula with relative sparing of the fovea and also were identified in the per

181 r PAMM illustrating a fern-like pattern with sparing of the periarteriolar area in all cases.

182 ions of the ICP and DCP in RP, with relative sparing of the SVC.

183 hinning and autofluorescence showed relative sparing of the temporal sector.

184 Presence of macular sparing, optic nerve visibility, less than 1 quadrant of

185 The mPEG carrier alone did not have bone-sparing or anti-inflammatory properties.

186 rsisted in adulthood, indicating very little sparing or recovery of function.

187 owever, a key unanswered question is whether sparing or sharing farming would best conserve functiona

188 plastic breast-conserving surgery and nipple-sparing or skin-sparing mastectomy with immediate breast

189 pe and timing of reconstruction after nipple-sparing or skin-sparing mastectomy with planned radiothe

190 h intensification of existing farmland (land sparing), or elevating biodiversity within the agricultu

191 mor mass loaded with high Z materials, while sparing other cells.

192 depolarization may affect some cristae while sparing others.

193 a substantial clinical advance, potentially sparing patients from the risks associated with surgical

194 od for identifying municipalities where land-sparing policies are most likely to succeed, and those w

195 The potential neurologic sparing, possibly via reduced volume of chronic inflamma

196 We also assessed the lymphocyte sparing potential in cardiac and splenic irradiation mod

197 Here, we evaluate the land sparing potential of solar energy development across fou

198 ets tissue rich in dendritic cells, has dose-sparing potential, and allows needle-free delivery.

199 nt with active surveillance (n = 363), nerve-sparing prostatectomy (n = 675), external beam radiation

200 n with favorable-risk prostate cancer, nerve-sparing prostatectomy was associated with worse urinary

201 eliminate pathogenic autoimmune cells while sparing protective immunity, but feasible strategies for

202 f the cavernous nerve (CN) network for nerve-sparing radical prostatectomy using near-infrared cyanin

203 me, functional imaging guidance during nerve-sparing radical prostatectomy.

204 on of treatment, participants receiving dose-sparing regimen.

205 city and may help prioritize patients for AG-sparing regimens in clinical settings where access is li

206 ding access to tenofovir disoproxil fumarate-sparing regimens in resource-limited settings.

207 g with the general preference for carbapenem-sparing regimens, suggests using ceftazidime or piperaci

208 In Drosophila, such brain sparing relies on a glia-derived growth factor to sustai

209 status in response to CRE, whereas the brain-sparing remodelling of the fetal circulation resulting f

210 te intense interest into how the fetal brain sparing response may be affected by adverse intrauterine

211 chronic loss of binocular dLGN inputs while sparing response strength and spatial acuity.

212 rd, as iron levels decline further, an "iron-sparing" response (fsrA, fbpAB, and fbpC) is induced to

213 ing in association cortices while relatively sparing responses in PAC, opening new avenues for future

214 tive lymphocytes in vitro and in vivo, while sparing resting lymphocytes.

215 ese data identify therapeutic and antibiotic sparing roles for vaginal immunomodulatory agents that s

216 ding aortic root replacement, Ross, or valve-sparing root operations (29% versus 45%; P<0.001).

217 cludes genes encoding Zn import (adcABC), Zn sparing (rpsN.2), and Zn scavenging systems (adcAII, pht

218 eous features at baseline, efficacy, steroid-sparing, safety, and relapses were recorded.

219 The MHV was resected in 6 patients, always sparing segments 4i and 5.

220 related to higher frequency of consciousness-sparing seizures (p < 0.02, Spearman's rho).

221 nical potential (TWh year(-1)) of these land sparing sites and test the degree to which projected ele

222 d in a young woman and affected the stomach, sparing small intestine and colon.

223 cking this pathway represents a coagulopathy-sparing, specific and novel therapy in acute liver failu

224 mics approach for core biopsies using tissue-sparing specimen processing and microscaled proteomics.

225 OCS-sparing strategies are extremely important to improve pa

226 levodopa, which led to misconceived levodopa-sparing strategies, have been largely mitigated by the o

227 placed with follow-up or less invasive organ-sparing strategies.

228 or subsequent CKD for early, proactive renal sparing strategies.

229 fIPV appears to be an effective dose-sparing strategy for routine immunisation and outbreak r

230 ursued to explore fIPV im as option for dose-sparing strategy in countries reluctant to use fIPV id d

231 ramuscular route and offers a potential dose-sparing strategy to stretch the limited global IPV suppl

232 faster than MTX in achieving corticosteroid-sparing success in ocular inflammatory diseases.

233 The onset of corticosteroid-sparing success took more than 3 months for most patient

234 rative interactions that underlie the energy-sparing super-relaxed (SRX) state, which are not seen us

235 n treating this group of patients, fertility sparing surgery and decrease of acute and long-term toxi

236 measuring bowel dysfunction after sphincter sparing surgery for rectal cancer.

237 Adrenal-sparing surgery is feasible in multiple endocrine neopla

238 Sphincter sparing surgery is oftentimes associated with bowel dysf

239 e, the addition of radiotherapy (RT) to limb-sparing surgery may result in higher local control rates

240 Adrenal-sparing surgery was done in 31 patients: three (10%) of

241 views all these aspects, in addition to limb-sparing surgery.

242 Tissue-sparing surgical techniques and carbon dioxide laser tre

243 Scaling was selective, sparing synapses that were large and lacked recycling en

244 event thrombotic complications of HIT, while sparing systemic hemostatic pathways.

245 T results in clinically meaningful cognitive sparing that significantly exceeds that of modern XRT pr

246 pattern of calcifications: small, symmetric, sparing the basal ganglia, and a stepping stone appearan

247 of the immunoproteasome beta5i subunit while sparing the constitutive beta5c subunit.

248 FA) can be myocardium selective, potentially sparing the esophagus during left atrial ablation.

249 , potentially direct pathway component while sparing the excitatory, potentially indirect pathway com

250 ar first in the perifoveal macula, initially sparing the foveal center, and over time often expand an

251 tive effect on all used in vitro cell-lines, sparing the highly differentiated podocytes in lower con

252 ible mechanism for attacking the virus while sparing the host cell.

253 T cells in treated and distant tumors, while sparing the intervening draining lymph node and spleen.

254 s lateral oscillations of the anterior body, sparing the need for 'action selection'.

255 homa cells from fresh biopsy specimens while sparing the normal lymphoid cells in the tumor microenvi

256 in other TORCH infections, while relatively sparing the other organ systems.

257 site by at least one prediction tool, while sparing the residues previously shown to be phosphorylat

258 etely to diseased cells while simultaneously sparing the surrounding healthy tissue.

259 ons have been observed in infarcts initially sparing the thalamus but interrupting thalamo-cortical o

260 ssue, 172 patients with an infarct initially sparing the thalamus were prospectively evaluated clinic

261 ncurrent radiosensitizing treatment, thereby sparing the urinary bladder.

262 4) and with a group with frontal lobe damage sparing the VMF (N = 12).

263 o selectively suppress the mutant gene while sparing the wild-type counterparts.

264 diphosphate (GDP)-bound form of KRAS(G12C), sparing the wild-type protein.

265 recruitment to the CNS-draining lymph nodes, sparing their liver-draining counterparts.

266 nd enhance targeting of CML stem cells while sparing their normal counterparts.

267 ication towards pathogen-specific antibiotic-sparing therapeutics that target core determinants of ba

268 a, subgroups for highly effective carbapenem-sparing therapy can be defined.

269 was also effective as an oral glucocorticoid-sparing therapy in patients relying on oral glucocortico

270 to the regions and 21% (21/100) of patients sparing these regions.

271 s various treatment options, including organ-sparing TMT.

272 T provided the optimal dose distribution and sparing to heart.

273 S: The First-line Antimetabolites as Steroid-sparing Treatment (FAST) uveitis trial screened 265 adul

274 disease eradication and might offer a kidney-sparing treatment alternative for these patients.

275 th methotrexate as first-line corticosteroid-sparing treatment did not result in superior control of

276 aT supplements as a complementary or steroid-sparing treatment for asthma.

277 adiation (CRT) regimen for selective bladder-sparing treatment of muscle-invasive bladder cancer.

278 ent duration and the need to compare steroid-sparing treatments to pericardiectomy.

279 s a viable targetable biomarker for podocyte-sparing treatments.

280 n shown to suppress peripheral T cells while sparing Treg cells expressing wild-type FOXP3, thereby p

281 resents a potential aGVHD therapeutic target sparing Tregs.

282 vel data from the Phase III benralizumab OCS-sparing trial, ZONDA, were weighted to match treatment e

283 r cancer (MIBC), radiotherapy-based, bladder-sparing trimodal therapy (TMT) that combines transurethr

284 it through anabolic activity in muscle while sparing undesired effects of benign prostate hyperplasia

285 cells, driving local tumour clearance while sparing uninjected tumours in immunodeficient mice.

286 f miR-345 and GEM, thereby facilitating dose-sparing use of GEM.

287 and factors related to, glaucoma after lens-sparing vitrectomy (LSV) surgery in advanced retinopathy

288 ad a higher incidence of glaucoma after lens-sparing vitrectomy.

289 and 787 nm light by macular pigment, foveal sparing was more readily demonstrable by green/UWF-AF an

290 No steroid sparing was observed in group 2.

291 At CT, subpleural sparing was seen in 11 of 14 (79%) and a reversed halo s

292 Steroid sparing was significant.

293 sified into the DWF and Willisian collateral sparing (WCS) groups.

294 affected poorly positioned nucleosomes while sparing well-positioned nucleosomes flanking the enhance

295 inimum urine output target is safe and fluid sparing when compared with the standard target.

296 lower vaccination costs through antigen dose-sparing, which is especially relevant in underserved cou

297 ely to enable both antigen and adjuvant dose sparing while retaining efficacy.

298 egy would selectively lower mutant HTT while sparing wild-type.

299 interdependent land uses, we found that land sparing would allow larger estimated populations of most

300 A fovea-sparing yellow subthreshold laser was safe and effective