ライフサイエンスコーパス: spark

1 plex genome analysis application to ADAM and Spark.

2 rray partition method by key-value format in Spark.

3 alcium transients, and intracellular calcium sparks.

4 surface, and yielded longer duration Ca(2+) sparks.

5 sed amplitude compared with diastolic Ca(2+) sparks.

6 ing to a different spatial firing pattern of sparks.

7 efractoriness and other properties of Ca(2+) sparks.

8 f RyR open probability favoring long-lasting sparks.

9 nsient amplitude, and suppressed late Ca(2+) sparks.

10 piezoelectric materials and microsystems can spark a new age in the field of medicine.

11 immunologically novel to humans, they could spark a pandemic when adapted to transmit between humans

12 Attacks on health care have sparked a large-scale exodus of experienced health worke

13 ian cancer, high-grade serous carcinoma, has sparked a major effort within the research community to

14 vere pain, but their addictive potential has sparked a misuse epidemic.

15 bial community-the Plastisphere-has recently sparked a multitude of scientific inquiries and generate

16 These findings have sparked a new field of exploration in sensory neurobiolo

17 dividual genes, transcriptomic analyses have sparked a new wave of discoveries.

18 This sparked a period of methodological reflection that we re

19 from patients treated with these drugs, have sparked a renewed enthusiasm in the study of KRAS and it

20 The advent of biosimilars has sparked a renewed interest in immunogenicity that has re

21 Recent studies have sparked a renewed interest in phase variation mediated t

22 high-throughput DNA sequencing technologies sparked a revolution in the field of genomics that has r

23 micro-nano-sized particles and fibers, have sparked a tremendous interest to utilize cellulose's int

24 Initial reports on magnetogenetics have sparked a vigorous debate on the plausibility of physica

25 Resultant Ca(2+) sparks activate plasma membrane Ca(2+) -activated K(+) (

26 ough RyR2s, but it did nearly abolish Ca(2+) spark-activated, large-conductance, Ca(2+)-activated K(+

27 Therapeutic control of late Ca(2+) spark activity may provide an additional approach for tr

28 100 nmol/L) promoted spontaneous Ca wave and spark activity, a cellular phenotype of ryanodine recept

29 f overlap-driven actinyl bond covalency will spark activity, and extend to numerous applications of R

30 stocysts positively correlated with the zinc spark amplitude (R = 0.9209).

31 Advances in mammography have sparked an exponential increase in the detection of earl

32 This has sparked an increased interest into the application of ad

33 Accordingly, Ca(2+)-spark analysis in isolated TG cardiomyocytes revealed re

34 y an underlying API implemented using Apache Spark and Giggle-based genomic indexing.

35 h CaMKIIdelta inhibition, CST reduced Ca(2+) spark and wave frequency, reduced Ca(2+) spark dimension

36 asmic reticulum, and the frequency of Ca(2+) sparks and arrhythmogenic Ca(2+) waves remains low.

37 , which showed diminished spontaneous Ca(2+) sparks and BK channel activity in bladder and urethra SM

38 nalyzed and repetitive Ca(2+) events (Ca(2+) sparks and Ca(2+) puffs) originating from clusters of Ca

39 altered Ca(2+) release dynamics (i.e. Ca(2+) sparks and Ca(2+) waves), how NOX2 is activated by and r

40 ith this, injured A/J fibres produced Ca(2+) sparks and Ca(2+) waves.

41 hannels are transiently activated by calcium sparks and calcium influx during action potentials and c

42 oxygen species signals that regulate calcium sparks and calcium influx pathways.

43 oscopy (line scan confocal imaging of Ca(2+) sparks and dual-tilt electron tomography) and dSTORM ima

44 hearts and myocytes, but enhances SR Ca(2+) sparks and leak on confocal microscopy.

45 nnels were activated by intracellular Ca(2+) sparks and mediated spontaneous transient outward curren

46 nhanced elementary Ca release measured by Ca sparks and promoted RyR2 (ryanodine receptor) structural

47 ich membrane depolarization increases Ca(2+) sparks and subsequent STOC production.

48 nt of current generated by these late Ca(2+) sparks and their (subsequent) spatiotemporal summation i

49 her localized Ca(2+) release, such as Ca(2+) sparks and waves, can cause local sarcomere contraction.

50 release of SR Ca(2+) through RyR2s ("Ca(2+) sparks") and corresponding Ca(2+)-activated K(+) channel

51 sarcoplasmic reticulum (SR) Ca releases (Ca sparks) and arrhythmogenic Ca waves.

52 Impact, spark, and friction sensitivity measurements, computatio

53 ADAM and Apache Spark are a performant and productive platform for imple

54 Calcium (Ca) sparks are elementary events of biological Ca signaling.

55 ABSTRACT: Ca(2+) sparks are generated in a voltage-dependent manner to in

56 Ca(2+) sparks are generated in a voltage-dependent manner to in

57 Calcium (Ca) sparks are the fundamental sarcoplasmic reticulum (SR) C

58 ons for zinc dynamics and establish the zinc spark as an extracellular marker of early human developm

59 s detailed, using a simple model of calcium 'sparks' as a testbed.

60 So Spark-based distributed parallel computing framework can

61 We report Spark-based INFERence of the molecular mechanisms of NOn

62 Here we describe an Apache Spark-based scalable sequence clustering application, Sp

63 ility experiments showed that loss of Ca(2+) spark-BK channel signaling in Mcoln1 (-/-) mice rendered

64 CRISPR-based homing gene drives have sparked both enthusiasm and deep concerns due to their p

65 Single-atom catalysts (SACs) have sparked broad interest recently while the low metal load

66 showed a larger cytosolic amplitude (Ca(2+) sparks) but smaller depletion (Ca(2+) blinks) than relea

67 which the economic and public health crises sparked by COVID-19 might increase food insecurity and c

68 evidence confirm that anaerobic respiration, sparked by labile organic matter, mobilizes P in this se

69 by a year and that the ensuing outbreak was sparked by long-lived lineages of Zika virus from other

70 zation reactions have undergone a resurgence sparked by recent discoveries in the field of catalytic

71 Consider the 60-year controversy sparked by Seaborg and co-workers when it was proposed t

72 This revolution has been sparked by technological advances that enable capture of

73 This interest is sparked by the combination of the inherent bioactivity o

74 PIs) are receiving increasing interest, much sparked by the realization that they represent druggable

75 ty counter-intuitively promotes long-lasting sparks by decreasing spark frequency.

76 g RyR open probability promotes long-lasting sparks by potentiating Ca-induced Ca release (CICR).

77 probability further suppresses long-lasting sparks by weakening CICR.

78 shed from synchronized leak (in long-lasting sparks) by larger Peierls contour lengths, an output par

79 t the transition from normal to long-lasting sparks can occur when ryanodine receptor (RyR) open prob

80 Zinc sparks can thus serve as an early biomarker of zygote qu

81 ar use of dedicated light-sensitive somatic 'spark' cells.

82 stributed onto multiple workers based on the Spark cloud computing platform.

83 XHMM), 12.7 min using 10 executor cores on a Spark cluster (18.8x speedup vs. XHMM), and 9.8 min usin

84 les in 292 min using 640 executor cores on a Spark cluster.

85 ed memory computers and large shared-nothing Spark clusters.

86 Transitions between modes are said to spark concerted changes in the morphology, physiology, b

87 AIDS 90-90-90 goals over the last decade has sparked considerable debate as to whether universal test

88 ered intermetallic nanoparticles (iNPs) have sparked considerable interest in fuel cell applications

89 wo-chromosome arrangement in V. cholerae has sparked considerable research interest since its discove

90 of Europe's most important fisheries and has sparked considerable scientific inquiry, most recently o

91 systems-wherein energy is not conserved-has sparked considerable theoretical advances.

92 yeast species in every subphylum of Dikarya) sparked curiosity but necessitated further efforts to ob

93 ata repository and private data, GsmPlot can spark data-driven ideas and hence promote the epigenetic

94 Recent work sparked debate over whether single-trial LIP spike train

95 sms and conditions that produce long-lasting sparks, demonstrating the existence of an optimal range

96 2+) spark and wave frequency, reduced Ca(2+) spark dimensions, increased sarcoplasmic reticulum Ca(2+

97 SPARK directly models spatial count data through general

98 Spark discharge (SD) and glow discharge (GD), as previou

99 nanoparticles (NPs) are fabricated by using spark discharge and manipulating the electric field.

100 es, which were generated using a Miller-Urey spark discharge apparatus with either a reducing or neut

101 The spectra acquired using a spark discharge coupled to the LIBS system were used for

102 A simple, fast, and efficient spark discharge-laser-induced breakdown spectroscopy (SD

103 om two PDOs were analyzed by LIBS coupled to spark discharge.

104 deuterated gases and reagents to compare the spark-discharge products of a "deuterated world" with th

105 ellular Ca(2+) release events ("late" Ca(2+) sparks) during phase 2-3 of the action potential.

106 an unmeasured trait drives LES covariation, sparking efforts to identify the latent physiological tr

107 ically and computationally that long-lasting sparks emerge as a collective dynamical behavior of the

108 Combined with FACS, SPARK enabled 51 fold enrichment of PPI-positive over PP

109 Racetrack memory (RM) has sparked enormous interest thanks to its outstanding pote

110 aterials naturally possessing a band gap has sparked enormous interest.

111 al (TWS), a new state of quantum matter, has sparked enormous research interest recently.

112 A new study by Sparks et al. now reports a small molecule that appears

113 ing infectious, result in more long-distance sparking events and less predictable disease trajectorie

114 er scanning confocal imaging captured Ca(2+) sparks evoked by voltage steps.

115 all cell types, including those in the lung, sparking exploration of clocks in lung disease pathophys

116 ABSTARCT: Graphene has sparked extensive research interest for its excellent ph

117 cal resolution evaluation algorithm based on Spark fine-grained 3D array partition has a magnitude ch

118 rpretation of experimental data or provide a spark for the discovery of a new function.

119 Here we present a statistical method, SPARK, for identifying spatial expression patterns of ge

120 Further, these changes affect Ca(2+) spark formation.

121 pipeline that is built on top of the Apache Spark framework, and is designed for fast real-time prof

122 We found that the spark frequency and amplitude increase nonlinearly with

123 yR inhibition, SN treatment decreased Ca(2+) spark frequency and dimensions in cardiomyocytes during

124 both increased sarcoplasmic reticulum Ca(2+) spark frequency and disrupted JMC integrity.

125 plasm produced a non-significant increase in spark frequency and reduced the P(i) effects on this par

126 ses in HF, when there is also an increase in spark frequency and spark-mediated Ca(2+) leak.

127 In HF there was an increase in spark frequency and spark-mediated Ca(2+) leak.

128 ) ](SR) confirmed a decrease correlated with spark frequency at high [P(i) ].

129 ed with isoform 3 of the RyR channel, Ca(2+) spark frequency is correlated with the Ca(2+) load of th

130 sed the effects of P(i) on [Ca(2+) ](SR) and spark frequency up to 55 mm [P(i) ].

131 ng experiments showed that postpacing Ca(2+) spark frequency was highest in intact CPVT PCs, but such

132 tion on mitochondrial Ca(2+) cycling, Ca(2+) spark frequency, and Ca(2+) amplitude, which agree well

133 vasive hemodynamics, without altering Ca(2+) spark frequency.

134 y promotes long-lasting sparks by decreasing spark frequency.

135 egrees C, cells at higher voltages exhibited sparks, fumes and fire.

136 These findings may spark further quality improvement efforts.

137 interest in these intermediates which might spark further research into their untapped potential for

138 ion surrounding stereotype threat while also sparking further research and debate.

139 This work may spark future investigations of topological states with c

140 amplitude, or kinetics of spontaneous Ca(2+) sparks generated by transient release of Ca(2+) from the

141 lyst systems; Fe nanoparticles from a plasma spark generator and cobaltocene and nickelocene precurso

142 ted electrochemical cell (SPC) based on iron-sparked graphite working electrode modified with glucose

143 roducing orexins (also known as hypocretins) sparked great advances in the field.

144 fforts to improve rigor and reliability have sparked great enthusiasm.

145 cannabis for a wide range of conditions has sparked great interest in other uses of CBD, in ethical

146 The growing human enterprise has sparked greater interest in identifying ecological thres

147 A normal Ca spark has a brief duration in the range of 10 to 100 ms,

148 Due to its high specificity and sensitivity, SPARK has the potential to advance PPI analysis and disc

149 ed to improve control over tumor growth have sparked hope that long-lived control of cancer through s

150 organic compounds (VOCs) for a wide range of spark ignition gasoline vehicles meeting varying levels

151 t (RD), residual oil (RO), diesel (DIE), and spark ignition vehicle emissions (GAS).

152 he filtration experiments was sampled from a spark-ignition direct-injection (SIDI) gasoline engine.

153 he code base, as the stepping stone toward a Spark implementation.

154 ects of solute-solvent interactions has been sparked in the field of supramolecular chemistry in gene

155 cal Ca signals known as puffs in neurons and sparks in muscle cells.

156 es with ryanodine receptors to induce Ca(2+) sparks in native arterial myocytes.

157 We studied the effects of P(i) on Ca(2+) sparks in permeabilized fibres of the frog.

158 PML1 is crucial for the initiation of Ca(2+) sparks in SMCs and the regulation of vascular contractil

159 orbiting double stars at close distances has sparked increasing scientific interest in determining wh

160 ocalized Ca(2+) release events (i.e., Ca(2+) sparks) independently of action potentials.

161 evelopment of a refractory period for Ca(2+) spark initiation after Ca(2+) release in cardiac myocyte

162 e lower SR Ca release threshold for local Ca spark initiation and exhibit steeper SR Ca release versu

163 zation of the semantic space of emotion-have sparked intense debate.

164 The Zika pandemic sparked intense interest in whether immune interactions

165 ophic event was considered unprecedented and sparked intense investigations to test this claim.

166 ich physical phenomena at the interface, has sparked intensive research on multiferroic heterostructu

167 nd water and ion transport in C1C2, and will spark interest in further experimental studies on the ch

168 We anticipate that these results will spark interest in this field and enable the replacement

169 al therapies, and its remarkable success has sparked interest in expanding checkpoint inhibitor thera

170 genome-wide association studies (GWASs) have sparked interest in gene cataloguing in the context of a

171 as a key regulator of energy expenditure has sparked interest in identifying novel soluble factors ca

172 cadian clocks on mammalian transcription has sparked interest in the interregulation of transcription

173 the neurotropic potential of SARS-CoV-2 has sparked interest in the role of the nervous system in re

174 child to the index environmental insult has sparked interest in transgenerational inheritance.

175 Recent research advances in photonics have sparked interest in using a network of coupled degenerat

176 ype 108 presented promising characteristics, sparking interest in its national and international comm

177 Synthetic cells spark intriguing questions about the nature of life.

178 ly higher sensitivity of the presented laser-spark ionization technique.

179 hich is based on penalized quasi-likelihood, SPARK is also scalable to datasets with tens of thousand

180 otic event termed the "zinc spark." The zinc spark is dependent on and occurs coordinately with intra

181 nism underlying these extremely prolonged Ca sparks is not understood.

182 We previously reported SPARK (Kim et al., 2017), a transcription factor that is

183 e blocked by tetracaine or ruthenium red, Ca sparks lasting hundreds of milliseconds have been observ

184 o investigate the possibility of late Ca(2+) spark (LCS) activity in intact isolated cardiac myocytes

185 This hypothesis has sparked major initiatives focusing on whole-genome and/o

186 the frequency, spread, amplitude and Ca(2+) spark mass relative to control, while the tomograms reve

187 T CT/GC amplified DNA assay (BD Diagnostics, Sparks, MD).

188 MD) and the Onclarity assay (BD Diagnostics, Sparks, MD).

189 France), and CHROMagar MRSA (BD Diagnostics, Sparks, MD).

190 using the Onclarity assay (Becton Dickinson, Sparks, MD).

191 e is also an increase in spark frequency and spark-mediated Ca(2+) leak.

192 there was an increase in spark frequency and spark-mediated Ca(2+) leak.

193 Iron-spark modification increases the response of the sensor

194 cured component of the global virosphere may spark new avenues for microbial manipulation approaches

195 As epidemiologists spark new conversations (e.g., see Kawachi (Am J Epidemi

196 ts a major reservoir of viruses, which could spark new epidemics in disease free countries or vaccina

197 ochemiluminescence (ECL) with nanotechnology sparked new analytical applications, in particular for i

198 heir potent in vitro antiplasmodial activity sparked new endeavors to synthesize members of this fami

199 ted by a series of recent studies which have sparked new hypotheses regarding the function of claustr

200 on single-atom catalysts (SACs), which have sparked new interests in electrocatalysis because of the

201 atively established discipline, has recently sparked numerous exciting findings on microglia, the res

202 We show that normal sparks occur when the CRU network is monostable and exci

203 monostable and excitable, while long-lasting sparks occur when the network dynamics possesses multipl

204 emporally overlapping events (e.g., a Ca(2+) spark occurring during the decaying phase of a Ca(2+) wa

205 The sparking of cut grape hemispheres in a household microwa

206 ong-range transmission events, half of which sparked onward transmission.

207 fferences in CRU size and complexity, Ca(2+) sparks originating from internal CRUs were of longer dur

208 and aggregation of human populations, which spark outbreaks and sustain transmission, respectively,

209 new pathway for fabricating WCu alloys using spark plasma infiltrating sintering of copper-coated gra

210 alpha-AlB(12) and B powders were reactively spark plasma sintered at 1800 degrees C.

211 this paper, the crystallization mechanism in spark plasma sintered Fe(48)Cr(15)Mo(14)Y(2)C(15)B(6) me

212 Cathodes were composed of spark plasma sintered Fe3O4 or alpha-Fe2O3 or field-extr

213 The mechanism of crystallization in this spark plasma sintered iron based metallic glass was esta

214 Here, a Flash Spark Plasma Sintering (FSPS) process has been applied t

215 The idea of flash spark plasma sintering (or flash hot pressing - FHP) ste

216 us ceramic/metal composites were obtained by spark plasma sintering (SPS) using ZrO2 and lamellar met

217 ther reduced to 0.7 W/m.K by Sb alloying and spark plasma sintering (SPS), which introduce additional

218 d by a simple hydrothermal route followed by spark plasma sintering (SPS).

219 A new ultra-rapid process of flash spark plasma sintering is developed.

220 A new flash (ultra-rapid) spark plasma sintering method applicable to various mate

221 Sintering was carried out via spark plasma sintering, during which the perovskite phas

222 f ND (2 - 10 vol.%) were synthesized here by spark plasma sintering.

223 manufacturing processes such as alloying and spark plasma sintering.

224 graphene foams with pre-ceramic polymers and spark plasma sintering.

225 fabricated via high-energy ball milling and spark plasma sintering.

226 c precursors in nitrogen and consolidated by spark plasma sintering.

227 pplied for holographic imaging through laser-spark plasma-generated shock-waves and to enable three-d

228 e strength and slip behaviour of grains of a spark-plasma sintered (Hf-Ta-Zr-Nb)C high-entropy carbid

229 restacking of the exfoliated layers via the spark-plasma-sintering technique (SPS).

230 imental observations illustrated that Ca(2+) spark production is intimately tied to the activity of b

231 ive selection of embryos based on their zinc spark profile significantly improved developmental outco

232 Moreover, the zinc spark profile was also associated with embryo quality as

233 Retrospective analysis of zinc spark profiles revealed that parthenotes and zygotes tha

234 spark builds upon the open source Hadoop and Spark projects, bringing domain-specific features for bi

235 These late Ca(2+) sparks prolong the Ca(2+) transient that activates contr

236 used to highlight the criticality in calcium spark propagation in relation to inter-dyad distances.

237 ential repolarization shows that late Ca(2+) sparks provide a mechanism for EAD initiation.

238 tbreak in the Federated States of Micronesia sparked public health concern.

239 ine ventricular myocytes increased diastolic spark rate and prolonged AP duration.

240 of AP duration and reduced diastolic Ca(2+) spark rate.

241 STIM1 expression also increased spark rates and induced spontaneous APs.

242 We anticipate that our results will spark renewed investigation in modulating the function o

243 While recent studies have sparked renewed interest in colour processing in Drosoph

244 with excellent potency and selectivity have sparked renewed interest in the selective targeting of S

245 These cells have recently sparked renewed interest, facilitated through the develo

246 eneration sequencing experiments, and Apache Spark represents a cost-effective solution with rapid de

247 Thus, we hypothesized that the zinc spark represents an early extracellular physicochemical

248 ng honey bees (Apis mellifera), has recently sparked research interests regarding pollinator health.

249 ." The ability of the gamete to mount a zinc spark response was meiotic-stage dependent.

250 Flint takes advantage of Spark's built-in parallelism and streaming engine archit

251 thmic optimizations and careful attention to Spark's configuration parameters.

252 This has sparked scientific debate on how to achieve natural clim

253 at TRPML1 is critically important for Ca(2+) spark signaling, and thus regulation of contractility an

254 The use of gene drives has sparked significant enthusiasm for genetic control of mo

255 entally, we measured RyR cluster sizes at Ca spark sites in rat ventricular myocytes and further test

256 nomic inequality in contemporary society can spark skepticism about the existence of economic opportu

257 We have developed SPARK (Specific Protein Association tool giving transcri

258 work in a coordinated manner to grade Ca(2+) spark/spontaneous transient outward currents (STOCs) in

259 work in a coordinated manner to grade Ca(2+) spark/spontaneous transient outward currents (STOCs) in

260 Thus, Spark SQL can replace existing practices to retrieve gen

261 With this modification, Spark SQL serves such joins more than 50x faster than it

262 e to this challenge is a modified version of Spark SQL, a distributed SQL execution engine, that hand

263 ration enables smooth muscle to grade Ca(2+) spark/STOC production and thus precisely tune negative e

264 ontribution of each Ca(2+) channel to Ca(2+) spark/STOC production depends upon their biophysical pro

265 t the voltage-dependent triggering of Ca(2+) sparks/STOCs is not tied to a single conductance but rat

266 ganization in transcriptional regulation has sparked substantial interest in the molecular mechanisms

267 ry of emergent phenomena in 2D materials has sparked substantial research efforts in the materials co

268 reservoir species, a tiny fraction of which spark sustained transmission in humans.

269 Since a long-lasting spark terminates via the Kramers' escape process over a

270 ts the Ca store depletion level required for spark termination for each cluster size.

271 lgorithm using the ADAM framework and Apache Spark that incorporates novel algorithmic optimizations

272 ncourage experienced doctors to rekindle the spark that initially motivated them to become physicians

273 atial-resolution model of the cardiac Ca(2+) spark that requires supercomputing resources for executi

274 ates localized elevations of Ca(2+) ("Ca(2+) sparks") that activate plasmalemmal large-conductance Ca

275 itive-functional linguists that we hope will spark the cross-disciplinary discussion necessary to pro

276 chemistry since 2015, and also endeavors to spark the curiosity of investigators who might enter thi

277 as viral infections or environmental toxins, spark the disease process in the brain and/or peripheral

278 These structures can spark the improved design of GM1 mimics, either alone or

279 Next-generation sequencing has sparked the exploration of cancer genomes, with the aim

280 agic-angle twisted bilayer graphene(4-8) has sparked the exploration of correlated electron states in

281 math (STEM) fields in the United States has sparked the formation of grassroots advocacy groups to e

282 Bicyclo[1.1.1]pentanes (BCPs) have sparked the interest of medicinal chemists due to their

283 the extracellular space in a prominent "zinc spark." The ability of the gamete to mount a zinc spark

284 ions in an exocytotic event termed the "zinc spark." The zinc spark is dependent on and occurs coordi

285 at The Children's Hospital of Philadelphia, Spark Therapeutics, US National Institutes of Health, Fo

286 hich implements parallel processing based on Spark to increase the speed and efficiency of performing

287 ed fine-grained 3D array partition method in Spark to parallel calculating 3D FSC for getting a 3D lo

288 uction of exome sequencing in the clinic has sparked tremendous optimism for the future of rare disea

289 his study should serve as a beacon that will spark up strategic planning, comprehensive water resourc

290 with a strong family history of pancreatitis sparked us to reexamine a large kindred originally repor

291 SPARK was used to detect 12 different PPIs in mammalian

292 ) signaling events spanning multiple pixels (sparks, waves, puffs, transients, etc.), from which spat

293 ially resolved transcriptomic datasets using SPARK, we show it can be up to ten times more powerful t

294 of spontaneous BKCa currents, but not Ca(2+) sparks were lower in cells from diabetic patients.

295 proposed framework was implemented on Apache Spark, which allows for easy and efficient utilization o

296 These new laws have sparked widespread debate, but we lack evidence on the t

297 sification of environmental disturbances has sparked widespread decline and compositional shifts in f

298 ipotent stem cells (iPSCs) over a decade ago sparked widespread enthusiasm for the development of new

299 n a new study by Muto et al., MDS stem cells sparked with TRAF6-activated innate immune signaling wer

300 the range of 10 to 100 ms, but long-lasting sparks with durations of several hundred milliseconds to

301 ovince, China and spread globally in months, sparking worldwide concern.