ライフサイエンスコーパス: specific immune response

1 , which was sufficient to trigger an antigen-specific immune response.

2 the activation of a clinically relevant AML-specific immune response.

3 col chitosan produced the most effective flu-specific immune response.

4 checkpoint of agonist quality necessary for specific immune response.

5 hanges that suggest modulation of the peanut-specific immune response.

6 e of gammadelta T cells in the mycobacterial-specific immune response.

7 s to that found following an influenza-virus-specific immune response.

8 the improved efficacy was a result of a Trp2-specific immune response.

9 encoding ovalbumin (MVA-OVA) on the allergen-specific immune response.

10 ed with the incomplete Ag OVA leads to an Ag-specific immune response.

11 ated the role of IL-10 in modulating the RSV-specific immune response.

12 of an rNDV vector to induce a potent antigen-specific immune response.

13 by using TLR synergy to enhance the parasite-specific immune response.

14 ing APC recruitment, activation, and antigen-specific immune response.

15 of glycolysis was sufficient to induce this specific immune response.

16 has been seen as a by-product of the myelin-specific immune response.

17 cells (MBCs) in the context of the influenza-specific immune response.

18 in C57BL/6) was used to evaluate the antigen-specific immune response.

19 antially depends on an individual's leukemia-specific immune response.

20 distant tumours by inducing a strong tumour-specific immune response.

21 hat sense danger signals and in turn trigger specific immune responses.

22 rived heat shock proteins can generate tumor-specific immune responses.

23 e system and evaluated the resulting antigen-specific immune responses.

24 ated with T-cell activation but not with CMV-specific immune responses.

25 y, despite eliciting strong and stable virus-specific immune responses.

26 al products to subvert production of antigen-specific immune responses.

27 chinery necessary to activate potent antigen-specific immune responses.

28 ith a considerable risk to transfer allergen-specific immune responses.

29 CD279), resulting in dis-inhibition of tumor-specific immune responses.

30 pedition (CHE), as activators of ICS1 during specific immune responses.

31 al symptoms of the disease and mounted virus-specific immune responses.

32 ften associated with rapid viral escape from specific immune responses.

33 seq technology we identify genes involved in specific immune responses.

34 activation and with absent to minimal HIV-1-specific immune responses.

35 urs independently of T-cell-mediated antigen-specific immune responses.

36 e survival overall survival, and rate of CEA-specific immune responses.

37 ction as immunological adjuvants for antigen-specific immune responses.

38 ed toxins can be administered to mount toxin-specific immune responses.

39 ection in the context of quantifying antigen-specific immune responses.

40 n AMA1 were the targets of protective allele-specific immune responses.

41 tive jawless vertebrates capable of mounting specific immune responses.

42 t it contributes to the induction of antigen-specific immune responses.

43 bioactive cytokines and to initiate pathogen-specific immune responses.

44 ed on the evidence that Tregs suppress virus-specific immune responses.

45 eptional plasticity that characterizes virus-specific immune responses.

46 portant antigens that induce T cell-mediated specific immune responses.

47 ll proliferation, and attenuation of antigen-specific immune responses.

48 nsors are required for induction of pathogen-specific immune responses.

49 ation of adaptive serum and local chlamydial specific immune responses.

50 that can trigger inflammation and induce Ag-specific immune responses.

51 r (GM-CSF) induces follicular lymphoma (FL) -specific immune responses.

52 osuppressive neutrophils and restoring tumor-specific immune responses.

53 ntibody production to induce primary antigen-specific immune responses.

54 irus antigens might prevent induction of HBV-specific immune responses.

55 ssary for the durable suppression of antigen-specific immune responses.

56 een, and brain and induced bacterial antigen-specific immune responses.

57 We next tested candidate-specific immune responses.

58 valence countries as well as on long-term TB-specific immune responses.

59 that express the NKG2C receptor mediate CMV-specific immune responses.

60 studies involving subjects with active HSV-2-specific immune responses.

61 n and a thorough understanding of early xeno-specific immune responses.

62 conventional dendritic cells can enhance Ag-specific immune responses.

63 ial utility of DNA vaccines in generating Ag-specific immune responses.

64 mphoma cells and its ability to induce tumor-specific immune responses, 11 has the potential to be us

65 Regarding CD8(+) T cell-mediated Ag-specific immune responses, a heterogeneous pattern of re

66 he vaccinated patients, the development of a specific immune response after vaccination was associate

67 We have elicited local genital antigen-specific immune responses after topical application of a

68 PDT can induce a potent antigen- and epitope-specific immune response against a naturally occurring m

69 en challenges, mainly in the form of a human-specific immune response against the vector that poses a

70 se mice become infected with HCV, generate a specific immune response against the virus, and develop

71 e infection we observe what is potentially a specific immune response against the virus; a non-synony

72 ngs suggest that dysregulation of macrophage-specific immune responses against an otherwise harmless

73 d evaluate their abilities to induce antigen-specific immune responses against CHIKV.

74 Specific immune responses against EBV-infected B cells w

75 xpressing the relevant VEGFR-2 CARs mediated specific immune responses against VEGFR-2 protein as wel

76 rate, the strength and efficiency of the non-specific immune response and characteristics affecting t

77 8(+) T cells is a hallmark of an adaptive Ag-specific immune response and constitutes a critical comp

78 that malignancy may initiate the scleroderma-specific immune response and drive disease in a subset o

79 in overdrive at the expense of the pathogen-specific immune response and is likely to underlie the m

80 egress that allows the development of a CNS-specific immune response and the classical pathological

81 nderlying the modulation of both the malaria-specific immune response and the course of clinical mala

82 mors regardless of the potent systemic tumor-specific immune response and the increases of tumor infi

83 o data demonstrate the emergence of pathogen-specific immune responses and a concomitant rise in plas

84 vailable on the relationship between antigen-specific immune responses and COVID-19 disease severity.

85 y of these vaccines to induce functional HCV-specific immune responses and determine T-cell cross-rea

86 Strong Ag-specific immune responses and homeostatic expansion of h

87 How these isolates drive specific immune responses and how this affects fungally

88 onses evoked by helminths may modify malaria-specific immune responses and increase the risk of malar

89 t this combination significantly enhances Ag-specific immune responses and leads to complete eradicat

90 l unit was further characterized by helminth-specific immune responses and microarray analyses.

91 nnate and human immunodeficiency virus (HIV)-specific immune responses and of the generalized inflamm

92 ish cf-mt-DNA release, thereby dampening age-specific immune responses and prolonging the survival of

93 iFT immune complexes, enhances F. tularensis-specific immune responses and protection against F. tula

94 summarise the current understanding of liver-specific immune responses and provide an outlook on futu

95 d LLO(91-99)/CD8(+)- and LLO(189-201)/CD4(+)-specific immune responses and recruited mature dendritic

96 nti-idiotype antibody to monitor a patient's specific immune responses and suggest routes for the imp

97 cine is structurally stable which can induce specific immune responses and thus, can be a potential v

98 of defective genomes, strong cellular HIV-1-specific immune response, and a high poly-functionality

99 Triplex elicited and amplified CMV-specific immune responses, and fewer Triplex-vaccinated

100 s linked with IgG2c isotype switching, virus-specific immune responses, and humoral autoimmunity.

101 ion, <2 copies/mL), T-cell activation, HIV-1-specific immune responses, and the persistence of cells

102 animals are able to develop efficient virus-specific immune responses, and thus can be employed for

103 of viral antigen expression, inadequate HBV-specific immune responses, and treatment regimens that r

104 ges for immunotherapy, measurement of tumour-specific immune responses, and understanding the associa

105 VIN elicited a statistically significant VZV-specific immune response approximately 28 days post-dose

106 d and elicited statistically significant VZV-specific immune responses approximately 28 days post-dos

107 Organ- and cell-specific immune responses are associated with the outcom

108 l IL-10 production and regulation of antigen-specific immune responses are controlled in vivo without

109 immunological factors that initiate the lung-specific immune responses are unclear.

110 of interventions targeting suppression of Ag-specific immune responses as a component of HIV cure str

111 We propose sequence coverage by HIV Gag-specific immune responses as a possible correlate of pro

112 Secondary endpoints were chikungunya virus-specific immune responses assessed by ELISA and neutrali

113 ystemic reaction that includes an acute, non-specific, immune response associated, paradoxically, wit

114 these individuals indicated a strong person-specific immune response at baseline, with little change

115 lished EAMG, and that the MDSCs inhibit AChR-specific immune responses at least partially in an Ag-sp

116 its and risks of inducing high levels of SIV-specific immune responses at mucosal sites prior to SIV

117 First, specific immune responses become exhausted if they are s

118 uding the magnitude and quality of influenza-specific immune responses before vaccination.

119 Prior to a detectable virus-specific immune response (before day 5), the estimated h

120 demonstrated better cellular uptake and OVA-specific immune response both in vitro and in vivo.

121 vants and found that they elicited unique Ag-specific immune responses both in vitro and in vivo.

122 es not only need to induce a robust tumor Ag-specific immune response but also need to overcome the t

123 human immunodeficiency virus type 1 (HIV-1)-specific immune responses but cannot control immune acti

124 characteristic modifications in the allergen-specific immune response, but a detailed synthesis of OI

125 helminths can not only downregulate parasite-specific immune responses, but also modulate autoimmune

126 Patients with celiac disease have gluten-specific immune responses, but the contribution of non-g

127 tain chemotherapeutic drugs stimulate cancer-specific immune responses by inducing immunogenic cell d

128 status does not affect the generation of GP-specific immune responses by these vaccines.

129 duction of robust and long-lasting transgene-specific immune responses by these vectors.

130 In this report we demonstrate that the Gag-specific immune response can be further enhanced by the

131 The types and magnitude of Ag-specific immune responses can be determined by the funct

132 cterized by the emergence of efficient virus-specific immune responses capable of restraining mutatio

133 despite CD8+ T cell- and B cell-mediated SIV-specific immune responses comparable to those observed i

134 The ovalbumin-specific immune response correlated with clinical respon

135 Impaired T. pallidum-specific immune responses could contribute to difference

136 T), HIV loads and frequencies of HIV epitope-specific immune responses decrease.

137 egardless of the level of total glycoprotein-specific immune response detected after vaccination, all

138 we report that the particularly strong virus-specific immune response during acute primary infection

139 nged mice survival, and the strong antitumor-specific immune response elicited upon poly A:U administ

140 (IRF) 3 and 7 in type I IFN induction and Ag-specific immune responses elicited by DNA vaccination.

141 We further demonstrated that such Ag-specific immune responses elicited by skin LCs were grea

142 ) play a critical role in modulating antigen-specific immune responses elicited by T cells via engage

143 human immunodeficiency virus type 1 (HIV-1)-specific immune responses elicited through vaccination a

144 developed attenuated lesions and reduced Ag-specific immune responses following infection with Leish

145 sed with AGS-004, no uniform increase in HIV-specific immune responses following vaccination was obse

146 immune regulatory pathways to enhance tumor-specific immune responses for the treatment of cancer ha

147 We compared the HIV-1-specific immune responses generated by targeting HIV-1 e

148 us clinical data, AGS-004 did not induce HIV-specific immune responses greater than those measured at

149 owledge of the gut microbiome's influence on specific immune responses has increased rapidly, also du

150 immunocompetent individuals.IMPORTANCE HCMV-specific immune responses have been extensively document

151 rofiles that affect their ability to mediate specific immune responses, here we generated IL-9-skewed

152 y reduced the LNP's ability to boost DEN-80E specific immune responses, highlighting the crucial role

153 e polymorphic nature of PvDBP induces strain-specific immune responses, however, and the epitopes of

154 t PrEP may also allow for development of HIV-specific immune responses, hypothesized to result from a

155 phospholipids and/or sterols, elicit a lung-specific immune response in Abcg1(-/-) mice.

156 (HIV) and hepatitis C virus (HCV) on the HCV-specific immune response in acute HCV infection are limi

157 OIT favorably modified the peanut-specific immune response in all subjects completing the

158 T-OVA showed limited cellular uptake and OVA specific immune response in contrast to short MWNT-OVA d

159 sciatic nerve and to terminate the P0106-125-specific immune response in EAN.

160 ation and specifically CARD11 in the antigen-specific immune response in human subjects.

161 whether PrEP affects the development of HIV-specific immune response in humans.

162 elicited a balanced cellular and humoral GP-specific immune response in mice.

163 ts of oral uptake of Mal d 1 on the allergen-specific immune response in patients with birch pollen a

164 this network in evoking a protective antigen-specific immune response in the brain remains unclear.

165 ver, the impact of chemotherapy on the tumor-specific immune response in the context of the tumor mic

166 r compounds from pollen enhance the allergen specific immune response in the skin and nose.

167 T-lymphocytes were used to study the antigen-specific immune response in vitro and in vivo.

168 limiting bystander cell injury during an Ag-specific immune response in vivo are largely unknown.

169 ation, viral population structure, and virus-specific immune responses in a longitudinal cohort of 15

170 m abscess formation, and stimulated pathogen-specific immune responses in a mouse model of staphyloco

171 to elicit potent systemic and mucosal virus-specific immune responses in adult nonhuman primates and

172 a (MVA) as a vaccine model, we characterized specific immune responses in all compartments of the FRT

173 ll intrinsic mechanism of evading metastasis-specific immune responses in breast cancer.

174 ic) T cell receptor (TCR) may supplement HBV-specific immune responses in chronic HBV patients and fa

175 ights the importance of understanding tissue-specific immune responses in disease pathogenesis.

176 ers either the frequency or magnitude of HIV-specific immune responses in HIV-1-exposed seronegative

177 Studies of influenza-specific immune responses in humans have largely assesse

178 onses at steady-state and on M. tuberculosis-specific immune responses in latent TB (LTB), we examine

179 FRs as important targets for enhancing tumor-specific immune responses in mice and man.

180 We addressed this question by assessing OVA-specific immune responses in mice following hepatocyte t

181 bility of HIV/SIV strategies to induce virus-specific immune responses in milk has not been studied.

182 Enhancement of mucosal HIV-specific immune responses in milk of HIV-infected mother

183 hat the vaccine is capable of inducing virus-specific immune responses in mouse models of acute and c

184 e expansion, HBV antigen expression, and HBV-specific immune responses in patients in the immune-tole

185 their potential for inducing robust antigen-specific immune responses in people with prior exposure

186 s by initiating, controlling, and driving Ag-specific immune responses in RA.

187 rotocols that elicited similar levels of Gag-specific immune responses in rhesus macaques.

188 , Konrad et al. present an example of fungus-specific immune responses in social ants that lead to th

189 steps of B and T cells and started to define specific immune responses in terms of the binding profil

190 es with disease course and evidence of HHV-6-specific immune responses in the CNS provide compelling

191 organism, Lactococcus lactis, to elicit HIV-specific immune responses in the mucosal and systemic co

192 with coincident DM, we examined mycobacteria-specific immune responses in the whole blood of individu

193 responses were common but did not impair Env-specific immune responses in this study.

194 o had diminished ability to induce bacterium-specific immune responses in vivo, as shown by immunoglo

195 caque skin are capable of inducing antiviral-specific immune responses in vivo.

196 ightens the intensity and breadth of antigen-specific immune responses in young and aged mice through

197 er immunotherapeutic approaches induce tumor-specific immune responses, in particular CTL responses,

198 fferent strategies to mount an efficient JCV-specific immune response including TCR bias, HLA cross-r

199 ) T cells are detectable among human antigen-specific immune responses, including pathogens such as i

200 pG-Stat3 siRNA generate potent tumor antigen-specific immune responses, increase the ratio of tumor-i

201 The fetal-specific immune response increased during pregnancy and

202 e a proper reflection of the M. tuberculosis-specific immune responses induced at the local site of i

203 HIV-1-specific immune responses induced by a dendritic cell (D

204 y reduces Mycobacterium tuberculosis antigen-specific immune responses, induces apoptosis in activate

205 s (HBV) infection persists because the virus-specific immune response is dysfunctional.

206 infectious virus from the CNS, and the virus-specific immune response is implicated as a mediator of

207 cells feedback to APCs to sustain an antigen-specific immune response is not completely clear.

208 A CML-specific immune response is thought to contribute to the

209 ur ability to monitor and manipulate antigen-specific immune responses is in its infancy.

210 comparison of infecting genotype and antigen-specific immune responses is possible.

211 tanding about the function of AAb in disease-specific immune responses is required in order to suppor

212 allograft steatosis influences post-OLT HCV-specific immune responses leading to an IL-17 T-helper r

213 samples were collected and analyzed for HBV-specific immune responses, liver damage, and viral param

214 t target immune activation and improve virus-specific immune responses may be needed.

215 Host SHIV-specific immune responses may play a role in the viremia

216 s was that ZVIN would elicit significant VZV-specific immune responses, measured by gpELISA or ELISPO

217 athology, they should not be used to predict specific immune responses occurring in lymphoid organs.

218 We sought to assess the functional, serotype-specific immune response of 12-month-old infants after i

219 Bet v 1-specific immune responses of 16 patients with birch poll

220 osal vaccination often induces serum antigen-specific immune responses of lower magnitude than those

221 cation of gp120 glycopeptide-induced, T cell-specific immune responses offers a foundation for develo

222 the effect of erythrocyte polymorphisms and specific immune responses on half-life variation.

223 duration over which control is maintained by specific immune responses open the door to rational desi

224 However, little is known about HIV-1-specific immune responses or inflammation in foreskin.

225 te the ability to generate pathogenic myelin-specific immune responses peripherally, MIF-deficient mi

226 Tissue-specific immune responses play an important role in the

227 We found that SasX induced a specific immune response predominantly based on IgG1 ant

228 e necessary signals to promote tumor antigen-specific immune responses, priming T cells that can be u

229 ng activated T cells to suppression of tumor-specific immune responses, providing a conceptual advanc

230 n heart valve bioprostheses, recipient graft-specific immune responses remain a significant cause of

231 -lymphoid tertiary organs and sustain tissue-specific immune responses remain undefined.

232 Identification of specific immune responses responsible for pathogen prote

233 evolving viral reservoir along with an HIV-1-specific immune response seems to be key for the spontan

234 sis antigen 85B significantly enhanced r30ML-specific immune responses, substantially more so than bo

235 g inflammation, but it can be detrimental in specific immune responses, such as sepsis and antitumor

236 concurrent approaches to favor tumor antigen-specific immune responses, such as vaccines or adoptive

237 ticles elicited significantly higher antigen-specific immune response than "out" nanoparticles and fr

238 he surrounding stroma reflects an anti-tumor-specific immune response that can be altered by stress.

239 not only kills CSCs but also elicits a tumor-specific immune response that converts dying CSCs into a

240 study to demonstrate a pre-infection dengue-specific immune response that correlates specifically wi

241 have the potential to induce a conformation-specific immune response that has a function-enhancing r

242 T-II CD4 T cells to track an in vivo antigen-specific immune response that was induced during the cou

243 vaccines may be explained in part by allele-specific immune responses that are directed against poly

244 hat the human airway epithelium mounts virus-specific immune responses that are likely to determine t

245 CD8(+) T cells mediate antigen-specific immune responses that can induce rejection of s

246 ory mediators and initiate adaptive, antigen-specific immune responses that collectively damage glome

247 2F5-epitope scaffolds showed levels of graft-specific immune responses that correlated with graft fle

248 ficacy depends upon the promotion of antigen-specific immune responses that inhibit reactivation or r

249 Alterations in other HIV-specific immune responses that may assist in eliminating

250 ur results show that this vector elicits HBV-specific immune responses that prevent the establishment

251 logy using sortase A mutants, raised antigen-specific immune responses that protected leukopenic mice

252 g bacteria stimulates systemic tumor-antigen-specific immune responses that reduce the growth of untr

253 thus a great need to define measures of DENV-specific immune responses that reliably indicate when im

254 V-1 prophylactic vaccine elicited robust HIV-specific immune responses that were similar to responses

255 al trials as cancer vaccines to induce tumor-specific immune responses that will improve clinical out

256 lasts in the blood may contribute to the HIV-specific immune response, the majority of these cells ar

257 In order to generate specific immune responses, the peptides chaperoned by HS

258 Although clinical cows expressed antigen-specific immune responses, the profile for subclinical c

259 Although Tregs inhibit specific immune responses, their inhibition of HIV repli

260 lso contribute to the regulation of allergen-specific immune responses through other mechanisms such

261 ponsible for orchestrating diverse, pathogen-specific immune responses through their differentiation

262 icity that is instrumental in shaping the Ag-specific immune response to DNA vaccines.

263 mong birds in the effectiveness of their non-specific immune response to MG, and that the host and pa

264 in determining the magnitude of the antigen specific immune response to vaccination with MVA85A in h

265 Antigen (Ag)-specific immune responses to chronic infections, such as

266 cluding efficient small RNA delivery and non-specific immune responses to dsRNA.

267 small-animal model with which to study human-specific immune responses to HIV would greatly facilitat

268 t these antigens to generate faster and more specific immune responses to minimize the P. vivax infec

269 allelic exclusion, is fundamental for highly specific immune responses to pathogens.

270 Since the potential of HIV-specific immune responses to provide protection against

271 Characterization of virus-specific immune responses to severe acute respiratory co

272 nd the effect of RIG-I activation on antigen-specific immune responses to the encoded antigen was det

273 T cells generate antigen-specific immune responses to their cognate antigen as a

274 While EBOV-specific immune responses to this candidate vaccine have

275 HMGN1 promoted antigen-specific immune response upon co-administration with ant

276 including APCs in mice, and promoted antigen-specific immune responses upon coadministration with an

277 Here, we studied the EBNA-1-specific immune response using the EBV-homologous rhesus

278 To measure varicella-zoster virus (VZV)-specific immune responses using glycoprotein enzyme-link

279 MHV68) infection, the generation of an MHV68-specific immune response was altered in the absence of A

280 A specific immune response was detected in the bone marrow

281 ability of Hmgn1(-/-) mice to mount antigen-specific immune responses was accompanied by both defici

282 e TB, but the capacity of D-Mtb to stimulate specific immune responses was not investigated.

283 assess the diagnostic potential of pathogen-specific immune responses, we characterized the local re

284 Cytomegalovirus-specific immune responses were boosted after each admini

285 Herein, we investigated whether specific immune responses were correlated with such symp

286 Measles-specific immune responses were evaluated in 70 children

287 Tumor-specific immune responses were induced with dendritic ce

288 HIV-1 reservoirs indicated that their HIV-1-specific immune responses were insufficient to effective

289 High levels of M2e specific immune responses were observed in the 4M2e-tFli

290 HIV and vector-specific immune responses were quantified post-boost vac

291 Peanut-specific immune responses were serially analyzed.

292 es, HBsAg transgenic mice, which show no HBV-specific immune response, were crossed to animals with h

293 such as cytomegalovirus generate huge virus-specific immune responses, which are further expanded in

294 Serotype-specific immune responses, which could promote diversity

295 inistration, we followed the endogenous ChgA-specific immune response with specific tetramers.

296 A paucity of data exist comparing xeno-specific immune responses with alloislet (AI) responses

297 ility and the preferential induction of type-specific immune responses with limited potency against h

298 cal coexistence of spontaneous tumor antigen-specific immune responses with progressive disease in ca

299 nctions as a weak but effective adjuvant for specific immune responses, with preferential effects on

300 vaccines based on alpha-Gal epitopes, human-specific immune responses, xenotransplantation studies,