ライフサイエンスコーパス: speculative

1 asome is activated in adipose tissue remains speculative.

2 whether the event is reported as negated or speculative.

3 m of how these associations interact remains speculative.

4 the long-term prognosis of psychosis remain speculative.

5 explain the underlying mechanisms have been speculative.

6 in sex determination in plants has been only speculative.

7 -equilibrium topology simplification remains speculative.

8 ecades of research, the cause of LCH remains speculative.

9 ll poorly understood and risk factors remain speculative.

10 , heritable disease, and oncogenesis remains speculative.

11 developed, their mechanism of action remains speculative.

12 erapeutic failure with l-asparaginase remain speculative.

13 A's role in post-nuclear entry steps remains speculative.

14 ole for P. jirovecii in pathogenesis remains speculative.

15 echanistic role in neurodegeneration remains speculative.

16 role in fructose-induced hypertension remain speculative.

17 choreography of steps that follow is largely speculative.

18 ne and schizoaffective disorder has remained speculative.

19 The mechanism of the hypoxia action remained speculative.

20 force, in the past and/or currently, remains speculative.

21 sitivity and the development of BCRL remains speculative.

22 netic code have been largely qualitative and speculative.

23 e mutations cause pancreatic disease remains speculative.

24 a-mediated cancer cell proliferation remains speculative.

25 that our understanding of visfatin is still speculative.

26 reduce triglyceride levels in humans remains speculative.

27 obial agents and primary vasculitides remain speculative.

28 its regulation by second messengers remains speculative.

29 ins, their contribution to cell loss remains speculative.

30 f GSTP1 in colorectal cancer biology remains speculative.

31 key genes or proteins have remained largely speculative.

32 The nature of this link remains speculative.

33 the brain in chronic pain conditions remains speculative.

34 hanistic explanations for HGTs have remained speculative.

35 ntributes to autoimmune pathogenesis remains speculative.

36 f the bioactive hormone is increased remains speculative.

37 rinary) significance of this finding remains speculative.

38 e precise role of transcription has remained speculative.

39 al differences between rods and cones remain speculative.

40 se two processes occur simultaneously remain speculative.

41 rimary pulmonary hypertension (PPH) has been speculative.

42 ution, for example natural selection, remain speculative.

43 ytotoxic cell granule-mediated death remains speculative.

44 ts in dendrites of pyramidal neurons remains speculative.

45 th this CD20 B-cell-directed therapy remains speculative.

46 changes on cure and/or complications remain speculative.

47 ate groups, yet their roles in vision remain speculative.

48 d cell death, yet the mechanism has remained speculative.

49 the time when colonization occurred remains speculative.

50 echanism of ssDNA binding in eukarya remains speculative.

51 eurotransmitters in vertebrates has remained speculative.

52 ion and mast cell (MC) degranulation remains speculative.

53 m, although a causative role in vivo remains speculative.

54 ausative or a secondary complication remains speculative.

55 tential mechanisms of such a relation remain speculative.

56 gene, however, this suggestion has remained speculative.

57 that supports a similar role in skin remains speculative.

58 are populations in the United States remains speculative.

59 The basis of this association remains speculative.

60 or this graft-versus-leukemia effect remains speculative.

61 s phosphatidylethanolamine (PE)/PC, is still speculative.

62 h, but their molecular pathogenesis is still speculative.

63 uitment to the central nervous system remain speculative.

64 molecular genetics of Down syndrome remains speculative.

65 but its intracellular function has remained speculative.

66 quantitative aspects of these methods remain speculative.

67 us vasodilator, such as NO, but this remains speculative.

68 on in neural coding, however, remain largely speculative.

69 ying the disease association of BRD1 remains speculative.

70 elta32)) can cure HIV, yet mechanisms remain speculative.

71 and proposed structures of these R-loops are speculative.

72 articles, links to specific eruptions remain speculative.

73 ng the evolutionary late amino acids remains speculative.

74 ts and hosts in deep time have long remained speculative.

75 o evidence, its role in vivo remains largely speculative.

76 to climate change, however, remains largely speculative.

77 encountered have, however, remained largely speculative.

78 erence means our understanding of drivers is speculative.

79 ctrophile binding sites and the pore remains speculative.

80 on of the cytoplasmic droplet have long been speculative.

81 never experimentally evaluated and remained speculative.

82 ectrical potential in the cleft has remained speculative.

83 ons to the primary motor cortex (M1) remains speculative.

84 al mechanisms involved in this effect remain speculative.

85 d origin of this Cl-bearing mineral remained speculative.

86 w the complex fulfills its function remained speculative.

87 ation to other national contexts must remain speculative.

88 ng molecule(s) in TSC cyst epithelia remains speculative.

89 fluctuations in microbial composition remain speculative.

90 these postoperative changes remains thus far speculative.

91 V outbreak in 2023 in Kerala, India, remains speculative.

92 This issue, however, has remained speculative.

93 lear and potential underlying mechanisms are speculative.

94 ading to patient phenotypes has been largely speculative.

95 cise explanation of this observation remains speculative.

96 egalized, widespread, or continued usage are speculative.

97 ar dynamics and gas exchange remains largely speculative.

98 examples in this popular field of study are speculative.

99 analogous to modern birds are intriguing but speculative.

100 potential role in bumble bee decline remain speculative.

101 owever, the source of those T cells has been speculative.

102 nd whose detailed wrapping topologies remain speculative.

103 its biological function has remained largely speculative.

104 ryas, approximately 12,800 years ago, remain speculative.

105 natural gas in the decline therefore remains speculative.

106 ontribute to the perception of touch remains speculative.

107 elanoma, though its role in melanoma remains speculative.

108 ty or constitute therapeutic targets remains speculative.

109 outcome of host-pathogen interactions remain speculative.

110 nt of central auditory circuits has remained speculative.

111 here and cloud formation remains essentially speculative.

112 een proposed but the mechanisms often remain speculative.

113 s leading to viral uncoating remains largely speculative.

114 anisms such as ion exchange reactions remain speculative.

115 c exposure and developmental outcome remains speculative.

116 effect of immunosuppressive therapy remains speculative.

117 for these calorie-independent effects remain speculative.

118 unknown, and the transport mechanism remains speculative.

119 limination from the circulation remain to be speculative.

120 tion of tandem genes in yeast remain largely speculative.

121 nd mechanistic basis of their action remains speculative.

122 g, yet its impact on memory function remains speculative.

123 ich subsequently impact on diabetes, remains speculative.

124 rom endogenous causes, although this remains speculative.

125 linical relevance of Blastocystis is at best speculative.

126 egulation by the various LOX isoforms remain speculative.

127 While such binding was speculative 20 years ago, it has now been established th

128 Although the role of Pg in RA remains speculative, a causative role for periodontitis as a chr

129 We suggest a speculative algorithm as to how these might be used in r

130 The biologic roles of these proteins remain speculative, although several features of THSD7A suggest

131 impacts of beef, pork, poultry, and another speculative analysis of cultured biomass.

132 ound species and elementary reactions remain speculative and based on organometallic chemistry.

133 existence of conformational epitopes remains speculative and controversial, and PrP transformation is

134 mechanism of pathogen movement is currently speculative and controversial.

135 isms for these associations, however, remain speculative and deserve further study.

136 ve, are of great interest but are inherently speculative and difficult to prove.

137 Although the pathogenesis of IBS remains speculative and is probably multifactorial, a prevailing

138 m of valve disease induced by these drugs is speculative and may be related to their serotonergic eff

139 echanisms of these apparent functions remain speculative and much work on the mechanism of selenoprot

140 In this speculative and opinionated discussion, we explore these

141 eneration and termination of VF in humans is speculative and remains to be determined.

142 This has led to speculative and sometimes conflicting models describing

143 rrently, however, treatment success is often speculative and subjective, and is rarely based on skin'

144 Ideal goals are useful but speculative and subjective.

145 ed underlying cognitive mechanism is largely speculative and that a reverse, more motivational, path

146 ial fluid uptake into the lymphatics remains speculative and unresolved.

147 other vertebrate group, its function remains speculative, and no study has identified its cellular ba

148 mately the manual analysis is also partially speculative, and therefore is not an absolute measure of

149 This speculative application of analogue study is exemplified

150 nal vasculitis is the most recent example of speculative application of the term to complex and rare

151 vefronts, and describes newly established or speculative applications and combinations of the two.

152 e apparent that gene transfer is no longer a speculative approach for treating malignancies.

153 In this speculative article, I argue that the expansion of econo

154 In this speculative article, I suggest that the TDP may represen

155 ange interactions is still controversial and speculative, as there is no direct evidence that distant

156 From preliminary, speculative associations to well characterized biochemic

157 they reflect known physical laws rather than speculative assumptions for thought experiments.

158 eatures of EV and the untested hypotheses or speculative assumptions that await experimental proof.

159 le in risk stratification/disease prediction speculative at best.

160 Thus, while speculative at this point and contingent on the transpla

161 e regional hippocampal vulnerability remains speculative at this time.

162 However, its evolutionary origins remain speculative because few studies have investigated the ex

163 However, these estimates are necessarily speculative because relevant data are scarce.

164 s contributions from resuspension events are speculative because they did not include direct load mea

165 portance of inverse agonist ligands is still speculative because this work is founded almost exclusiv

166 ind" endoscopic procedures with "random" or "speculative" biopsy.

167 anges of information among individuals cause speculative bubbles, behavioral cascades, and other corr

168 At least when they are driven by speculative bubbles, market prices for food staples (and

169 The latter approach is the most speculative, but also the most promising in terms of tra

170 The effects of the new policy are inevitably speculative, but predictions can be made based on recent

171 Their origin is still speculative, but since their counterparts in the bone ma

172 A speculative, but testable, model for the maintenance of

173 velopment of Guillain-Barre syndrome remains speculative, but the possibility of molecular mimicry be

174 His speculative claims manifest a form of fundamental attrib

175 the FrzZ-RpoE1 interaction therefore remains speculative, cloning and sequencing of the region surrou

176 Dark matter, proposed decades ago as a speculative component of the universe, is now known to b

177 We conclude with a speculative conceptual model for the stepwise emergence

178 kes both comparison of their functions and a speculative consideration of the intriguing possibility

179 This perspective begins with a speculative consideration of the properties of the earli

180 clinical manifestations provided ground for speculative debate.

181 nes into public health practice by resolving speculative debates about practical costs and benefits.

182 sms and potential causal links have remained speculative despite decades of research.

183 ical understanding of these bacteria remains speculative despite the availability of substantial geno

184 arison of self to others), and bipedalism (a speculative developmental hypothesis about the neurologi

185 thers the artists' depiction only supports a speculative differential diagnosis.

186 l present a somewhat biased and occasionally speculative discussion of the current and future signifi

187 Finally, we conclude with a speculative discussion of what future informatics develo

188 This chemistry remains speculative due to a lack of detailed information concer

189 on's formation and timing of incision remain speculative due to a lack of direct constraints and geom

190 idate loci, however, this hypothesis remains speculative due to the current lack of methodologies for

191 red at the cancer site; the second is a more speculative, dynamic variant in which agents themselves

192 yubiquitin chains are formed remains largely speculative, especially for RING-based ligases.

193 This speculative Essay explores the consequences of the imagi

194 Additional speculative estimates of years of remaining life expecta

195 n reduce this problem by limiting the use of speculative evidence, integrating existing knowledge int

196 Although speculative, expression of HPV45 and/or the PIK3CA mutat

197 equences of learning and memory to a largely speculative extent.

198 Speculative fiction examines the leading edge of science

199 ed by lack of replication, small studies and speculative findings.

200 In a speculative forward look at the theoretical biology of c

201 A speculative function in polarization sensitivity is disc

202 The speculative function of this CDP in the carbohydrate met

203 le in immune host defense of the CNS remains speculative, given the immune privilege of this organ.

204 ploid - the first of these issues being more speculative, given the status of the field.

205 hock synthesis of diamond and lonsdaleite, a speculative hexagonal carbon polymorph with unique hardn

206 y of using OER at seawater RO plants remains speculative, however attractive.

207 in systems neuroscience neglect to test new speculative hypotheses against benchmark empirical facts

208 We end with a speculative hypothesis reconciling the striking differen

209 heory" or "quantum theory," and to suggest a speculative hypothesis, often relying on mathematical an

210 theory was formulated but was discarded as a speculative idea without any chance of empirical confirm

211 In this review, we describe speculative ideas and early stage research concerning th

212 onfer health benefits has its origins in the speculative ideas that are more than a century old, yet

213 A speculative illustration was proposed for possible modes

214 s of this counter-regulatory cytokine remain speculative in many disease models.

215 nsity of transmission to mosquitoes, is more speculative in nature but is convincingly demonstrated f

216 n of these patient and environmental factors speculative in nature but presents an opportunity for fu

217 onal function for specific behaviours remain speculative, in vertebrates and invertebrates.

218 of action of many of the enzymes are at best speculative, indicating a need to develop methods to cha

219 outstanding gaps in the literature and offer speculative insight for questions that remain to be expe

220 nd professionals alike, but may also provide speculative insight into models of care that attenuate t

221 Finally, we share some speculative insights into possible future directions for

222 riant SHELL alleles impact yield, as well as speculative insights into the potential role of SHELL in

223 One possible, albeit speculative, interpretation of these data is that the pr

224 into a discussion about some newer and more speculative interpretations of the data.

225 Both causes of price increase, speculative investment and ethanol conversion, are promo

226 While obviously speculative, it is interesting to consider possible phys

227 the pathophysiology of the myopathy remains speculative, its occurrence appears to be dose related.

228 angiogenesis inhibitors, since there is only speculative knowledge of the target.

229 complexity, most oocytes, for reasons still speculative, lack the major microtubule organizing cente

230 erence in these natural systems has remained speculative, lacking insights from sufficiently complex

231 uld enable faster desiccation in the wake of speculative late ocean scenarios(23).

232 hanistic schemes of its functioning beyond a speculative level.

233 ollective behavior and dynamic assembly; (4) speculative links to equilibrium thermodynamics.

234 xistential risk" narrative, which is largely speculative, may distract from the less dramatic but rea

235 or-driven transport, we devised and tested a speculative means to sidestep these limitations in filop

236 A speculative mechanism for the loss of TBP-induced writhe

237 ase reported here have enabled us to propose speculative mechanisms for color determination in firefl

238 tutions without invoking positive selection, speculative mechanisms, or implausible coincidence.

239 Speculative mechanistic considerations are offered regar

240 We propose a speculative, mechanistic model for linker function based

241 The generally accepted, albeit speculative, mechanistic model in the field postulates t

242 We present a speculative model for diverse functional roles of TFIID

243 A speculative model is presented that may explain the appa

244 A speculative model is proposed, relating current concepts

245 We propose a speculative model of how the T4 gene 59 helicase assembl

246 We have proposed a speculative model of the neurobiology of wisdom involvin

247 We present a speculative model on the possible roles of the ADA/GCN5

248 Our results support a speculative model that when V. cholerae reaches high den

249 We propose a speculative model whereby, during colonization, C. albic

250 Current data suggest a highly speculative model, in which two of the proteins ejected

251 In this speculative model, ligand binding induces dissociation o

252 We suggest several speculative models for the action of SUM1-1 in silencing

253 these recent biophysical studies and provide speculative models that address these unanswered questio

254 lly indirect (toolkits, associated fauna) or speculative (models, actualistic experiments).

255 In re-trade markets scope is given to speculative motives unavailable where goods perish on pu

256 A speculative overview of processes leading to formation o

257 wever, the details of these processes remain speculative owing to the lack of a complete description

258 r knowledge of this state of matter is still speculative, owing to the extreme difficulty in recreati

259 influence the world's biota remains largely speculative, owing to the many ways in which it can dire

260 The authors draw speculative parallels with the alveolar simplification p

261 sm of this essential process remains largely speculative, partly due to lack of knowledge of the pre-

262 eem to be important in relation to the still speculative pathogenesis: (a) increased transcription an

263 We present a speculative pathway of transcriptional activation involv

264 identified known and a number of previously speculative pHis sites inferred by homology, predominant

265 t appear unique to humans, including several speculative possibilities that require further study.

266 the basis of experiences, intuition or even speculative predictions, namely 'rules of thumb'.

267 t are immediately consumed, but they produce speculative price bubbles in resalable asset markets.

268 higher as traders are more likely to accept speculative prices.

269 Speculative rates of lake-level change suggest that the

270 While this hypothesis remains largely speculative, recent studies using different mouse models

271 are computed by multiplying small and highly speculative risk factors by large populations of patient

272 portion increased to 60% when the three more speculative risk factors were considered as well.

273 excess weight, and hypertension, and 2) more speculative risk factors, namely elevated protein intake

274 Here we review known and speculative roles that immune signaling plays in the pos

275 p an algorithm integrating watermarking with speculative sampling, an efficiency technique frequently

276 Explored here is an alternative, albeit speculative, scenario in which hyperinsulinemia and insu

277 es feel so vulnerable to what remain largely speculative scenarios.

278 midylyl-(3',5')-deoxyadenosine, has remained speculative since it was identified a decade ago.

279 sequent stimulus, but this interpretation is speculative since most studies to date have not used tas

280 We propose a speculative "spring" model for Gag3 during assembly.

281 first time a much fuller, if still partially speculative, story of the earliest years of this importa

282 ignificance of these data is discussed and a speculative structural model for this complex is suggest

283 Although speculative, such a paradigm for intratumoral drug deliv

284 nknown number of species, which has led to a speculative taxonomy.

285 Although speculative, the global nature of the decreases in messe

286 beta-rich oligomers in prion pathogenesis is speculative, the misfolding behavior could, in part, exp

287 gh the mechanisms directing targeting remain speculative, the ratio of MSL protein to roX RNA influen

288 ugh the mechanism of the association remains speculative, the results of this study have important cl

289 Although still speculative, the results suggest that the internal conne

290 expert examination for diagnosis of VSD are speculative, the role of echocardiography in such diagno

291 ided behavioral responses to quinine remains speculative, their possible function in oromotor reflex

292 Although still speculative, these emerging concepts, new diagnostic too

293 hydroisocoumarin biosynthesis remain largely speculative today.

294 review is to draw attention to emerging and speculative topics in this field where we posit that foc

295 Patents claiming genes with purely speculative utilities should not be issued, and they pos

296 This Perspective offers a speculative view on the molecular origins and pathophysi

297 Although speculative, we also found evidence that several, potent

298 h heritable polygenic editing (HPE) is still speculative, we completed calculations to discuss the un

299 development seem to be profound, it remains speculative whether the gut microbiota influences extrai

300 rtality they cause in mainland areas remains speculative, with large-scale estimates based on non-sys