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1 ale) and type of gametogenesis (oogenesis or spermatogenesis).
2 the MRT-mediated TSE for the preservation of spermatogenesis.
3 h Hbs1 to regulate multiple processes during spermatogenesis.
4 ue would be needed for the effective TSE for spermatogenesis.
5 germ cells which plays an essential role in spermatogenesis.
6 fore, and concurrent with, the initiation of spermatogenesis.
7 ng the replication errors that accrue during spermatogenesis.
8 mpromise the blood-testis barrier, impairing spermatogenesis.
9 tion of the retrogene encoding RBMXL2 blocks spermatogenesis.
10 oduction, as well as exocrine function, with spermatogenesis.
11 al stem cells (SSCs) are essential for adult spermatogenesis.
12 rans retinoic acid (ATRA) is instrumental to spermatogenesis.
13 ropriate splicing of key genes necessary for spermatogenesis.
14 and open to intercellular traffic throughout spermatogenesis.
15 ssion occurred in the post-meiotic stages of spermatogenesis.
16 substitute the wild type protein for normal spermatogenesis.
17 These genomes abruptly disappear during spermatogenesis.
18 s timely activation of germline genes during spermatogenesis.
19 nes that are preferentially expressed during spermatogenesis.
20 TB-BM axis by modulating BTB dynamics during spermatogenesis.
21 ession pattern but is subject to MSCI during spermatogenesis.
22 same pathway in either the nervous system or spermatogenesis.
23 pathways are tightly coordinated to support spermatogenesis.
24 ng MPA is teratogenic and may also influence spermatogenesis.
25 s are activated to enable the progression of spermatogenesis.
26 hey commit to, and prepare for, oogenesis or spermatogenesis.
27 ranscription of over 4000 genes during human spermatogenesis.
28 coordinates with DNA methylation to regulate spermatogenesis.
29 ng RNA biogenesis, transposon silencing, and spermatogenesis.
30 (piRNAs) and their role in TE regulation in spermatogenesis.
31 RNAs, most of them previously not linked to spermatogenesis.
32 mitosis-meiosis transition is essential for spermatogenesis.
33 ve effects of the GCY-35 hyperoxia sensor on spermatogenesis.
34 is appeared to be more sensitive compared to spermatogenesis.
35 cluding steroid biosynthesis, apoptosis, and spermatogenesis.
36 ndent transmission of DNA methylation during spermatogenesis.
37 trolling the earliest cell fate decisions in spermatogenesis.
38 ould reseal the disrupted BTB and reinitiate spermatogenesis.
39 s reduced substantially during post-pubertal spermatogenesis.
40 ground, which demonstrate similar defects in spermatogenesis.
41 ignificance of ubiquitin modification during spermatogenesis.
42 4b(Sox2)) mouse, to investigate its roles in spermatogenesis.
43 ential roles for AGO-bound small RNAs during spermatogenesis.
44 and subsequent germ cell development during spermatogenesis.
45 e to give rise to spermatocytes and maintain spermatogenesis.
46 deling to a condensed state is a hallmark of spermatogenesis.
47 ial differentiation, which is a key step for spermatogenesis.
48 nally is required for kidney development and spermatogenesis.
49 e deletion study revealed a role for PRL2 in spermatogenesis.
50 o marks retarded histone removal during late spermatogenesis.
51 lized H3K36 demethylation during meiosis and spermatogenesis.
52 ound small RNAs, are essential for mammalian spermatogenesis.
53 riants with a large effect in the process of spermatogenesis.
54 ically required during the meiotic stages of spermatogenesis.
55 mouse, and are reduced in men with impaired spermatogenesis.
56 e past six decades: testis determination and spermatogenesis.
57 d(+/+) mice, indicating that PPARD modulates spermatogenesis.
58 The infertility results from defects in spermatogenesis.
59 that may be altered in males with disrupted spermatogenesis.
60 matozoa and to the elaborate organization of spermatogenesis.
61 during development, long before oogenesis or spermatogenesis.
62 de is working in concert with EB1 to support spermatogenesis.
63 spermatocytes and is a critical regulator of spermatogenesis.
64 or stem cell engraftment and regeneration of spermatogenesis.
65 or stem cells led to sustained donor-derived spermatogenesis.
66 o-spermatogonia (SG) serve as the gateway to spermatogenesis.
67 ce defects in the upper airway, and abnormal spermatogenesis.
68 ion of somatic niche cells, and the onset of spermatogenesis.
69 ensure the unidirectional differentiation of spermatogenesis.
70 esult in the inability to maintain long-term spermatogenesis.
71 but little is known about their roles during spermatogenesis.
72 tuned by the level of gene expression during spermatogenesis.
73 acquired, or idiopathic factors that impair spermatogenesis.
74 is important for metabolic tailoring during spermatogenesis.
75 n to be associated with RE expression during spermatogenesis.
76 matin organization in male germ cells during spermatogenesis.
77 ups of mRNAs expressed at specific stages of spermatogenesis.
78 th and docking to the plasma membrane during spermatogenesis.
79 activation of select mRNAs in later steps of spermatogenesis.
80 d by Sertoli cells, thus leading to impaired spermatogenesis.
81 le gonad, is essential for the completion of spermatogenesis.
82 complex, results in a meiotic arrest during spermatogenesis.
83 and cooperates with the PIWI pathway during spermatogenesis.
84 for Smed-TTBK-d in postmeiotic regulation of spermatogenesis.
85 the RNA surveillance complex Pelota-Hbs1 in spermatogenesis, a function that could be conserved in m
86 rovides cytoprotection to maintain mammalian spermatogenesis, a highly thermosensitive process that m
88 s associated with increased risk of impaired spermatogenesis among nonirradiated male survivors of ch
89 results highlight interesting variations in spermatogenesis among the hymenopteran insects, and toge
90 vivo and exhibit gene expression related to spermatogenesis and diminished proliferation, a hallmark
91 These biomolecules are now known to support spermatogenesis and effectively enhance paracellular and
93 underpin the spatiotemporal coordination of spermatogenesis and ensure its prodigious output in adul
95 xpression of Rpl10 in spermatocytes restores spermatogenesis and fertility in Rpl10l-deficient mice.
97 ters but became infertile due to collapse of spermatogenesis and loss of undifferentiated spermatogon
102 emale germ cells are usually produced during spermatogenesis and oogenesis, which take place in the t
105 tes the transcription of genes essential for spermatogenesis and pre-configures sperm with a chromati
106 ody, spermatid development and completion of spermatogenesis and provide an avenue for the developmen
107 cantly fewer gonocytes and exhibit defective spermatogenesis and reduced sperm count as young adults.
108 We found that loss of PRL1 does not affect spermatogenesis and reproductive ability of male mice, l
109 e mice, genetic ablation of Pramef12 arrests spermatogenesis and results in sterility which can be re
110 ehensive survey of the functions of Huwe1 in spermatogenesis and reveal Huwe1's critical role as a mo
112 ns to stimulate or enhance oocyte production-spermatogenesis and sperm quality abnormalities are much
114 to simulated microgravity on Earth disrupts spermatogenesis and testicular testosterone synthesis in
115 lls is essential for the lifelong support of spermatogenesis and the development and lifelong health
116 tochondrial DNA, as has been observed during spermatogenesis and the early stages of embryogenesis.
117 mosome 21, the chromatin condensation during spermatogenesis and the extensive epigenetic reprogrammi
118 udy indicates that the meiosis of first wave spermatogenesis and the following spermatogenesis starte
119 -13 signaling impacts gene expression during spermatogenesis and the sperm's mitochondria, thereby in
121 rranted to determine how this SNP influences spermatogenesis and to assess its clinical utility in ch
124 OX gene cluster may function in normal human spermatogenesis and we provide evidence that it is impai
127 xactly how drive males compensate for failed spermatogenesis, and how such compensation may trade-off
128 results show that CUL4B is indispensable to spermatogenesis, and it functions cell autonomously in m
129 sing over, its functional specialization for spermatogenesis, and its high degree of sequence amplifi
130 hormones, small testes or ovaries, impaired spermatogenesis, and lack of ovulation in male and femal
133 ted tolerance of aneuploidy during mammalian spermatogenesis, and the surprisingly robust ability of
134 increased germ cell apoptosis and disrupted spermatogenesis, and whether these effects are mediated
137 itotic proliferation precedes meiosis during spermatogenesis, are observed in a wide variety of organ
138 ferous epithelium in mammalian testis during spermatogenesis, are tightly coordinated by biologically
141 after depletion of mitofusins Mfn1 and Mfn2, spermatogenesis arrests due to failure to accomplish a m
143 ese are SSCs that contribute to steady state spermatogenesis as well as regeneration following chemic
144 ensitive expressions, testicular physiology, spermatogenesis, as well as its role in male fertility i
146 n2 (-/-);Cetn3 (GT/GT) double-knockout mice, spermatogenesis-associated 7 (SPATA7), a key organizer o
149 s led to substantial up-regulation of a male spermatogenesis-associated protein 5-like gene (NlSPATA5
151 gest that overexpression of Cx43 reinitiated spermatogenesis at least through the steps of meiosis to
153 is spatially and temporally regulated during spermatogenesis being most highly expressed in the haplo
154 n and the temporal distribution of phases of spermatogenesis between juvenile (born that season) and
156 st be strongly selected to enable successful spermatogenesis, both driving the response away from ess
157 Ptbp2 is also abundantly expressed during spermatogenesis, but its role in this developmental prog
158 ef increase in temperature, cells undergoing spermatogenesis, but not oogenesis, activate transposons
159 antiapoptotic relative BCL-W is required for spermatogenesis, but was considered dispensable for all
161 n essential role during the meiotic stage of spermatogenesis by compensating for MSCI-mediated transc
162 addition to PRL2, PRL1 is also required for spermatogenesis by downregulating PTEN and promoting Akt
163 veal for the first time that PPARD regulates spermatogenesis by modulating the function of Sertoli ce
168 mical screening on a complex process such as spermatogenesis could be facilitated by cell culture app
170 ound that Grasp55-deficient mice suffer from spermatogenesis defects similar to Jam-C knockout mice.
171 )) resulted in complete male infertility and spermatogenesis defects, including deformed acrosomal fo
172 t spermiation, a physiological checkpoint in spermatogenesis, determines the egress and tolerogenicit
173 years old), whilst juveniles that commenced spermatogenesis did so later in the year than adults, in
176 V, could reversibly induce the impairment of spermatogenesis, disruption of BTB integrity, and germ c
177 e proteins involved in processes relevant to spermatogenesis; e.g. stress protection and cell surviva
178 d (v) M. daubentonii commenced and completed spermatogenesis earlier than M. nattereri in the equival
179 ) older males (aged >=4 years old) commenced spermatogenesis earlier than young adult males (aged 1-3
180 emale germ cell divisions after the onset of spermatogenesis, even young fathers contribute three tim
181 e results illuminate a novel role for MK2 in spermatogenesis, expand the repertoire of RNA-binding pr
182 tosterone production, and observed that many spermatogenesis features were impaired at 160 microg/ml
185 lly depleted, and can be replaced to promote spermatogenesis from surviving (host) spermatogonia.
186 et of endogenous proteins through RCs during spermatogenesis, from two-cell diploid spermatogonia to
187 autosome (so-called large-X theory); second, spermatogenesis genes are enriched on the autosomes but
188 As specifically targeting the down-regulated spermatogenesis genes is significantly up-regulated in h
192 the role of mitochondria in later stages of spermatogenesis has been investigated in depth, the role
194 he age of onset of male puberty and rates of spermatogenesis have likely had in hominids (great apes)
195 rgans with rapidly evolving pathways such as spermatogenesis, immune response, mother-fetus interacti
196 -based single-cell RNA-Sequencing to profile spermatogenesis in adult animals and at multiple stages
197 onia in insects, and its expression promotes spermatogenesis in germ cells when they are present in a
203 hat BRD7 is involved in male infertility and spermatogenesis in mice, and BRD7 defect might be associ
204 I-PpoI is expressed from a transgene during spermatogenesis in mosquitoes, the paternal X chromosome
205 tance of this alternative MPC complex during spermatogenesis in placental mammals remains unknown.
207 approaches to visualize landmark aspects of spermatogenesis in the jewel wasp Nasonia vitripennis, a
210 ith high transfection efficacy would perturb spermatogenesis, in particular, spermatid adhesion (i.e.
212 ies and differences in expression throughout spermatogenesis, including the stem/progenitor pool of s
213 MIWI catalytic activity is required for spermatogenesis, indicating that piRNA-guided cleavage i
214 atic cells but is not absolutely required in spermatogenesis, indicating tissue-specific roles in cen
221 ysis of germline substitutions suggests that spermatogenesis is a highly reparative process, with the
225 enance of undifferentiated spermatogonia and spermatogenesis is dependent on tightly co-ordinated tra
226 standing of the cell biology and genetics of spermatogenesis is difficult for most species because it
228 n mice, our current understanding of primate spermatogenesis is limited to populations defined by sta
229 n comparison to oogenesis in many organisms, spermatogenesis is particularly sensitive to small tempe
235 ecifically, in the testis there is a lack of spermatogenesis, lack of leydig cells and lack of mature
238 repetitive sequence expression during human spermatogenesis may play a role in regulating chromatin
239 , functions in diverse activities, including spermatogenesis, metabolism and stem cell self-renewal a
242 n this Primer, we summarize the processes of spermatogenesis occurring in two pivotal model animals -
245 important during oogenesis, had no effect on spermatogenesis or male fertility under normal condition
246 lection of Y chromosome-bearing sperm during spermatogenesis or male fetuses early in the course of c
250 defines the nuclear piRNA pool during mouse spermatogenesis, our findings uncover an unexpected conc
251 n gene expression are well known to modulate spermatogenesis, posttranscriptional mechanisms are less
252 s commonly expressed in somatic lineages and spermatogenesis-progenitor cells undergo repression in a
255 f piRNA biogenesis, transposon silencing and spermatogenesis, protecting the germline genome in mice.
256 -cell transcriptomic data of human and mouse spermatogenesis provide evidence that this widespread tr
257 hism suggests that temperature stress during spermatogenesis provides a unique opportunity for transp
258 ated in germ cells during multiple stages of spermatogenesis, ranging from the pachytene to the round
259 he role of the sex chromosomes in regulating spermatogenesis (recent reviews [17-20]), most studies d
265 tant spe-45 worms seemed to normally undergo spermatogenesis (spermatid production by meiosis) and sp
266 first wave spermatogenesis and the following spermatogenesis started from spermatogonium is probably
270 olves reproductive organs can cause impaired spermatogenesis, testosterone deficiency, and physical s
271 lity, testicular steroidogenic capacity, and spermatogenesis that were more severely impaired than th
272 the first transcriptomic atlas of A. gambiae spermatogenesis that will expand the available toolbox f
276 the distribution of genetic novelties across spermatogenesis, this study provides a deeper understand
277 erferes with the completion of oogenesis and spermatogenesis through sexually dimorphic mechanisms: i
278 lectively destroying the X-chromosome during spermatogenesis, through the activity of a naturally-occ
279 spermatogonial stem cell (SSC) that supports spermatogenesis throughout adult life resides within the
280 Spermatogonial stem cells (SSCs) maintain spermatogenesis throughout adulthood through balanced se
281 ead, HP1E primes paternal chromosomes during spermatogenesis to ensure faithful segregation post-fert
283 ogenesis, the postmeiotic phase of mammalian spermatogenesis, transcription is progressively represse
284 re we conducted a genetic study for impaired spermatogenesis utilizing whole-genome sequencing data f
289 und that the initiation of meiosis following spermatogenesis was not affected and the germ cells were
292 roaches with a novel in vitro model of human spermatogenesis, we demonstrate that exposure to PBB153,
293 oiting experimental advantages of Drosophila spermatogenesis, we found that the Wdb subunit localizes
294 gate the role of the phospho-GRTH species in spermatogenesis, we generated a GRTH Knock-In (KI) trans
295 on of histones is important at many steps in spermatogenesis, we performed a complete characterizatio
296 nal mechanisms upon which TAF4b functions in spermatogenesis, we used two-hybrid screening to identif
299 atogonial stem cells (SSCs) are the basis of spermatogenesis, which is dependent on the ability to se
300 ZCWPW1, which is tightly co-expressed during spermatogenesis with Prdm9, as an essential meiotic reco