ライフサイエンスコーパス: spike

1 mpacts the interaction with SARS-CoV-2 viral spike.

2 tprint are key to stabilizing the pre-fusion spike.

3 sion of and infection with pp-VSV-SARS-CoV-2 spike.

4 events cellular infection with pp-SARS-CoV-2 spike.

5 atitis virus (VSV) expressing the SARS-CoV-2 spike.

6 with a lower likelihood of postoperative IOP spike.

7 envelope and the progressive spacing of the spikes.

8 o association with procedural success or IOP spikes.

9 forms of selectivity use the same number of spikes.

10 nsient GTPase oscillations and RhoA activity spikes.

11 lope studded with crown-like, electron-dense spikes.

12 ile mice of either sex during high-frequency spiking.

13 either sex during repetitive high-frequency spiking.

14 tivate distinct and opposing patterns of NAc spiking.

15 citatory currents that drive more persistent spiking.

16 procedure were mild inflammation (13%), IOP spikes (6%), hyphema, corneal edema, and BCVA loss (all

17 y indication that patients infected with the spike 614G variant have higher COVID-19 mortality or cli

18 and O-glycans had only minor contribution to Spike-ACE2 binding.

19 GC pyramidal neurons, eliciting phase-locked spiking across trials and tastants.

20 and are not characterized by any spontaneous spike activity.

21 Directly comparing synaptic and spiking activity can determine whether this input-output

22 rtal vagal afferents failed to inhibit their spiking activity during glucose infusion, a GLP-1r-depen

23 riments are the first to record synaptic and spiking activity during sharp wave ripple (SWR) events i

24 We recorded spiking activity from single units in the auditory corte

25 Here we recorded spiking activity in 435 neuronal clusters evoked by acou

26 actal (self-similar) fluctuations in ongoing spiking activity in subcortical (lateral geniculate nucl

27 Spiking activity is more likely to occur during E/I imba

28 has been little evidence linking changes in spiking activity that occur prior to a spatially predict

29 th monkeys' behavior and showed uncorrelated spiking activity.

30 te values and arise independent from somatic spiking activity.

31 s showed that MAb binds to the virus surface spike, allowing it to undergo conformational changes and

32 obodies that disrupt the interaction between Spike and ACE2.

33 iated with increased number of spikelets per spike and decreased kernel size.

34 MVA (sMVA) vectors co-expressing SARS-CoV-2 spike and nucleocapsid antigens, two immunodominant anti

35 es necessary for the detection of SARS-CoV-2 spike and nucleoprotein detection was approximately 2 x

36 a flexible up conformation of the RBD on the spike and relies on antibody avidity for neutralization.

37 erformed in vitro antibody selection for the spike and the RBD proteins using both unbiased and biase

38 ositive in the assays with both the trimeric spike and the receptor-binding domain proteins.

39 S proxies, we developed AESP models: one for spiked and another for control soils.

40 ncy of this suspect screening tool to detect spiked and nonspiked chemicals in human blood.

41 To this end, we analyzed a total of 1,027 spikes and 86 seizures.

42 with adaptive learning rate clipping of loss spikes and an auxiliary trainer network.

43 ent source density patterns evoked by Ca(2+) spikes and describe resulting medial-frontal EEG on a ma

44 by the analysis of the impact of interictal spikes and fitting to the neuroimaging data.

45 Both spikes and seizures were associated with intense synchro

46 We used multiple electrodes to record BG spiking and field potentials during normal sleep and in

47 le stimuli were associated with increases in spiking and in gamma-band (40 to 90 Hz) power/connectivi

48 e effects of anesthesia on cortical neuronal spiking and information transfer could help illuminate t

49 ts due to the recent history of postsynaptic spiking and slow changes in postsynaptic excitability.

50 subthreshold or suprathreshold for dendritic spikes), and (3) the stimulation of neighboring synapses

51 The M, spike, and N proteins each accounted for 11%-27% of the

52 AR-mediated Ca(2+)-currents during the spine spike, and ultrastructural data prove NMDAR presence wit

53 CoV), bat CoV HKU5 expressing the SARS-CoV-1 spike, and vesicular stomatitis virus (VSV) expressing t

54 r when the pesticide pulse followed the heat spike, and was buffered by the heat spike when this was

55 t of tDCS on neural oscillations rather than spiking, and findings that tDCS administration to the pr

56 ection (LOD) of M. tuberculosis H37Rv in all spiked animal samples were 2 CFU/ml compared to 15.6 CFU

57 oth of these regions at the top of the viral spike are immunogenic.

58 ed from ongoing presynaptic and postsynaptic spiking are highly uncertain, our results are partially

59 thin this complex proteomics background, BSA spiked at 1:5:10 ratios was detected at ratios of 1.00:4

60 lse negative rate of up to 80% for chemicals spiked at low levels in blood.

61 ncy oscillations in the field potentials and spikes at the theta (8 Hz) band, and that low-frequency

62 was assessed to be in the range 94-125% for spiking at levels approximately 4 and 10 times LOQ.

63 lescent plasma donors, higher levels of anti-spike avidity were associated with older age, male sex,

64 However, the relationship between such a spiking-band power (SBP) and neural activity remains unc

65 nown as Benign Epilepsy with Centro-temporal Spikes (BECTS) or Rolandic Epilepsy, is one of the most

66 However, the spiking behavior of cortical neurons associated with suc

67 Recoveries of the enrichment step from spiked bovine serum albumin digests were >80% for the co

68 The relative recovery values for the spiked breast milk samples were in the acceptable range

69 ly measure protein concentrations in protein-spiked buffer, serum, and urine in seconds with excellen

70 ide a possible mechanism linking spontaneous spike bursts to tonotopic map refinement and further hig

71 ial on the number and magnitude of collision spikes by changing the applied potential in chronoampero

72 Global proteomics shows that the spiked CAII is the only protein with a log(2) ratio cons

73 ctivity at various stages, including somatic spiking, calcium signals at somata and axons, and striat

74 bacterial cells from pure cultures, culture-spiked cattle feces, and culture-spiked ground beef.

75 ormance of the sensor was confirmed using TM spiked chicken soup, resulting in a high percentage reco

76 i retention is confirmed by analyzing the Ni-spiked compact COx samples, whereby an increase of the N

77 ) structure of a neutralizing monoclonal Fab-spike complex revealed an epitope that blocks ACE2 recep

78 the recovery results obtained for different spiked concentrations (20, 30 and 40 ug L(-1)) were rema

79 was observed at less than 3% relative to the spiked control brains), we were unable to detect the oth

80 so an interesting strategy to detect current spikes corresponding to single redox DMPC liposome colli

81 Here we engineered the spike D614G substitution in the USA-WA1/2020 SARS-CoV-2

82 Hamsters infected with SARS-CoV-2 expressing spike(D614G) (G614 virus) produced higher infectious tit

83 n the maximal rates of voltage change during spike depolarization and repolarization.

84 cryosectioned chicken breast with a thallium spike deposited within the tissue.

85 We characterized 100 structure-guided spike designs and identified 26 individual substitutions

86 elow 50 muV(pp), much smaller than a typical spike detection threshold, at optical stimulation of >50

87 LFP events in the DG: high-amplitude dentate spikes (DSs), and a novel event type whose current sourc

88 rydendroid IPSC size depended on presynaptic spike duration rather than amplitude.

89 that attractor dynamics that control neural spiking during mnemonic periods interact with activity-s

90 ell culture and, in contrast to a stabilized spike ectodomain, is tolerant of exposure to temperature

91 bands depending on the area contributing the spikes, exhibited a specific directionality of informati

92 Spike experiments confirm a linear signal response.

93 change of pattern compared to that from the spiked feed.

94 and 45 days after fever onset, pneumonia and spiking fevers remitted, but relapsed after discontinuat

95 Spike fidelity was affected by both presynaptic and post

96 fter training and alters synaptically evoked spike firing and integrative properties of these neurons

97 tionships, back-propagation-activated Ca(2+) spike firing, and a shift in the critical frequency by b

98 ion of synchronous GABA release, synchronous spike firing, and evoked-gamma power increase with lower

99 self depending on a transient suppression of spike firing.

100 stress increases basolateral amygdala (BLA) spike firing.

101 correlations between interictal hippocampal spike frequency during waking and the first cycle of NRE

102 Spikes from inhibitory interneurons (cartwheel cell) and

103 expressing a modified form of the SARS-CoV-2 spike gene in place of the native glycoprotein gene (VSV

104 ls are present together with non-cooperative spike-generating conductances.

105 d altered climbing fiber (CF)-evoked complex spike generation, as well as increased amplitude and fas

106 tein, double stranded RNA, and RNA probe for spike genes were evaluated for the ability to detect FFP

107 SARS-CoV-2 spike glycoprotein (S)-reactive antibodies were detectab

108 milarly to SARS-CoV, SARS-CoV-2 utilises the Spike glycoprotein on the envelope to recognise and bind

109 eocapsid protein and distinct inserts in the spike glycoprotein that appear to be associated with hig

110 receptor-binding domain within its trimeric spike glycoprotein to human angiotensin-converting enzym

111 OVID-19) pandemic, are focused on SARS-CoV-2 spike glycoprotein, the primary target for neutralizing

112 erform structural modeling of the SARS-CoV-2 spike glycoprotein.

113 composed of trimeric full-length SARS-CoV-2 spike glycoproteins and Matrix-M1 adjuvant.

114 es, culture-spiked cattle feces, and culture-spiked ground beef.

115 On POD1, the incidence of IOP spike >40 mmHg was significantly higher at 14.4% in the

116 seline IOP predicted higher odds of POD1 IOP spike >40 mmHg, whereas the presence of HMS was associat

117 the spike protein have demonstrated that the spike has a role in MHV pathogenesis and retrograde axon

118 Persistent neuronal spiking has long been considered the mechanism underlyin

119 tory results for the detection of AMP in the spiked human serum samples.

120 s used alone or in combination with the anti-spike IgG assay to determine baseline status.

121 ad a stronger positive correlation with anti-spike IgG avidity (Spearman rho = 0.386; P < .001) than

122 to the pesticide chlorpyrifos and to a heat spike in the larvae of the mosquito Culex pipiens.

123 in both phosphate buffered saline (PBS) and spiked in E. coli cell lysate.

124 ERBB2 levels spiked in metastatic breast cancer between 10.0 and 4.0

125 r results show that activation of interictal spikes in the hippocampus during sleep and seizures spec

126 nce Material) and recovery experiments after spiking in food samples (Tea, coffee, chocolate, spinach

127 In addition, by spiking in known amounts of HCPs to purified antibody dr

128 treatments, which does not rely on exogenous spike-in chromatin or peak detection to reveal global ch

129 by using telomeric repetitive DNA as native spike-in control.

130 etrospectively renormalizes datasets without spike-in is lacking.

131 a similar magnitude of global changes as the spike-in method does.

132 os of the MS ion responses against the known spiked-in ratios (CVs < 8% for calibration standards).

133 ic neurons (mEC LVa and LVb) as well as fast-spiking inhibitory interneurons receive direct excitator

134 ausally implicate the minority striatal fast-spiking interneuron population as a key component of com

135 ions, we show that networks of striatal fast-spiking interneurons (FSIs) are capable of generating de

136 hat DMS medium spiny neurons (MSNs) and fast-spiking interneurons (FSIs) encoded such information and

137 chanism realizing this enhancement uses fast spiking interneurons (FSIs) in the striatum to train str

138 se from a deficit in the recruitment of fast-spiking interneurons by excitatory inputs during adolesc

139 Parvalbumin-expressing striatal fast-spiking interneurons comprise ~1% of the total neuronal

140 properties closely resembling those of fast-spiking interneurons, consistent with previous transcrip

141 iter SARS-CoV-2 remnant patient specimen was spiked into pooled SARS-CoV-2 RNA-negative specimen remn

142 When multiple proteins were spiked into the real urine, multivariate analysis was ab

143 E2 binding affinity of the entire SARS-CoV-2 spike is comparable to or lower than that of SARS-CoV sp

144 nferring synaptic effects from extracellular spiking is challenging.

145 ching in molecular films show random current spikes, just opposite to the expectation.

146 ced sound-driven firing rates, reduced first-spike latencies and wideband increases in excitability.

147 e standard deviations were <20% at all three spiking levels, while intraday and interday precisions w

148 However, coherence and spike-local field potential (LFP) coupling between the t

149 ivity, we quantified the rate of spontaneous spiking measured by multielectrode arrays at extended ti

150 nt transduction process and the axon hillock spiking mechanism of the olfactory sensory neurons (OSNs

151 fferent nerve, we further build a power-free spiking mechanoreceptor system with a passive piezoelect

152 the ability of endocytic mutants to enhance Spike-mediated fusion with the plasma membrane.

153 l ionization mass spectrometry (TIMS) double-spike method and produce unbiased seawater Pb isotope co

154 ct temporal profiles, we developed a reduced spiking model of sensory cortical circuits that incorpor

155 The model replicated the Ca(2+) spike morphology and its critical frequency plus three o

156 virus and support continuing surveillance of Spike mutations to aid with development of immunological

157 This work unifies balanced spiking networks with Poisson generalized linear models

158 lithiated phase of Li(4) Ti(5) O(12) toward Spiking Neural Network applications, due to the shorter

159 igate the stationary response of networks of spiking neurons as a function of coupling strength.

160 The narrow-spiking neurons showed similar changes but to a lesser d

161 n memristive links between brain and silicon spiking neurons that emulate transmission and plasticity

162 his was not the case for neighboring regular-spiking neurons.

163 uorescence microscopy is used to monitor the spiking of populations of neurons in the brain.

164 ng one tone counterintuitively decreased the spiking of Pyr neurons to a subsequent tone 400 ms later

165 ant had a significant response to SARS-CoV-2 spike or nucleocapsid protein in the ELISPOT assay.

166 dict the development of epilepsy better than spikes or spike ripples and might be useful biomarkers i

167 ow that licking activity strongly shapes the spiking pattern of GC pyramidal neurons, eliciting phase

168 s and entorhinal grid cells exhibit distinct spike patterns in different environments, a circuit func

169 nts and compared these results to the neural spiking patterns recorded in two male monkeys performing

170 asing ~15-fold from the prespike foot to the spike peak.

171 trode and enabled the selective detection in spiked plasma as well as in whole blood samples.

172 Childhood epilepsy with centrotemporal spikes, previously known as Benign Epilepsy with Centro-

173 eline antibody status was determined by anti-spike (primary analysis) and anti-nucleocapsid IgG assay

174 re, we developed metagenomic sequencing with spiked primer enrichment (MSSPE), a method for enriching

175 ictive of survival and IgA against the viral spike protein (S protein) associated with rapid virologi

176 Both SARS-CoV-2 spike protein (S-protein), a critical element of the vir

177 the nucleoprotein (N), the S1 domain of the spike protein (S1), and a lateral flow immunoassay (LFI)

178 ometry assay for the detection of SARS-CoV-2 spike protein and nucleoprotein in a relevant biological

179 Recombinant full-length spike protein and nucleoprotein were digested and proteo

180 ercial antibodies generated against SARS-CoV spike protein and nucleoprotein, double stranded RNA, an

181 protein of SARS-CoV-2 is more sensitive than spike protein antibody for detecting early infection.

182 ibody tests (99.3% and 99.7%) than using the spike protein antibody test (97.8%; P <= 0.002).

183 nteraction surface, which greatly influences Spike protein binding mode.

184 G inhibited angiotensin-converting enzyme 2-spike protein binding to a greater degree than controls.

185 in the receptor-binding domain (RBD) of the spike protein can neutralize the virus.

186 self-amplifying RNA encoding the SARS-CoV-2 spike protein encapsulated within a lipid nanoparticle (

187 The full-length Spike protein functioned inefficiently with all three sy

188 strains that differ in the gene encoding the spike protein have demonstrated that the spike has a rol

189 higher level of sequence variability in the Spike protein interaction surface, which greatly influen

190 We found that the spike protein of PDF2180-CoV, a MERS-like virus found in

191 l responses.RESULTSWe found responses to the spike protein of the 3 common cold coronaviruses in many

192 The spike protein on the surface of SARS-CoV-2 is a major an

193 ts receiving dialysis in July, 2020, using a spike protein receptor binding domain total antibody che

194 oV-2 uses the receptor-binding domain of its spike protein S1 to attach to the host angiotensin-conve

195 , which is triggered by binding of the viral spike protein to angiotensin-converting enzyme 2.

196 ability of plasma to inhibit the binding of spike protein to angiotensin-converting enzyme 2.

197 s disease 2019 (COVID-19) and expressed anti-spike protein trimer immunoglobulin G inhibited angioten

198 l and increasing frequency of the SARS-CoV-2 spike protein variant D614G are suggestive of a selectiv

199 eptor-binding domain (RBD) of the SARS-CoV-2 spike protein was developed and compared to three commer

200 eptor binding domain (RBD) of the SARS-CoV-2 spike protein(1).

201 ies that specifically bind the S1 SARS-CoV-2 spike protein, and block the interaction with the human

202 receptor binding domain (RBD) of SARS-CoV-2 spike protein, and subsequently tested with samples of a

203 to produce a prefusion-stabilized SARS-CoV-2 spike protein, S-2P.

204 piratory syndrome coronavirus 2 (SARS-CoV-2) spike protein, used in a combined cocktail (REGN-COV2) t

205 Based on the sequence of 2019-nCoV spike protein, we apply this predictive framework to pro

206 the immunogenicity of different parts of the spike protein, we performed in vitro antibody selection

207 ssion of strains with a H49Y mutation in the Spike protein, which could be further used as a molecula

208 y, the Wuhan-Hu-1 reference sequence for the Spike protein, which is the basis for different vaccine

209 ctor Bb is increased in the supernatant from spike protein-treated cells.

210 veral ACE2 orthologs bound to the SARS-CoV-2 spike protein.

211 flow immunoassay (LFI) based on full-length spike protein.

212 ing the receptor-binding domain (RBD) of the spike protein.

213 igen-specific T cells against the SARS-CoV-2 spike protein.

214 Spike-protein-reactive T cell lines generated from SARS-

215 estricted the entry mediated by the envelope spike proteins of other human coronaviruses, including t

216 ed similarly to the C-terminal region of the spike proteins of the human endemic coronaviruses 229E a

217 or serum antibodies to the nucleocapsid and spike proteins were analyzed using luciferase immunoprec

218 residues, which are conserved in coronavirus spike proteins, are predicted to be electrostatically fr

219 candidate, NIH-CoVnb-112, blocks SARS-CoV-2 spike pseudotyped lentivirus infection of HEK293 cells e

220 We show that SARS-CoV-2 Spike-pseudotyped virus and genuine SARS-CoV-2 infection

221 We challenge organoids with SARS-CoV-2 spike pseudovirus and live virus to demonstrate viral tr

222 In contrast, we observed a 46% spike rate reduction during SWRs in PV basket cells (PVB

223 el desynchronized brain state with increased spike rate variability, sample entropy, and EMG activity

224 on was mediated by the binding of SARS-CoV-2 spike RBD domain.

225 Notably, IgG against the spike receptor binding domain (RBD) was predictive of su

226 cterized IgG, IgM, and IgA antibodies to the spike receptor binding domain (RBD), S1+S2, nucleocapsid

227 Antibodies targeting the SARS-CoV-2 spike receptor-binding domain (RBD) are being developed

228 Spike recoveries of Cr(VI) are 98-102% and precision bet

229 ar how neocortex maintains this asynchronous spiking regime.

230 ng revealed the presence and location of the spiked region.

231 EPSCs in the KO explain the altered complex spike responses, which degrade information transfer from

232 ngle-unit recordings revealed transient fast spiking responses to the cue and reward in correct trial

233 evelopment of epilepsy better than spikes or spike ripples and might be useful biomarkers in the esti

234 tial EEGs were visually analyzed for spikes, spike ripples, and ripples.

235 Our analysis identified the spike (S) and nucleocapsid (N) proteins as promising tar

236 ive for anti-SARS-CoV-2 antibodies targeting spike (S) and nucleoprotein (N).

237 l models, we demonstrate that the SARS-CoV-2 spike (S) glycoprotein exhibits a high-affinity motif fo

238 rbors a polybasic furin cleavage site in its spike (S) glycoprotein.

239 An interaction between the coronaviral spike (S) protein and its receptor is the primary determ

240 body structures associated with the SARS-CoV spike (S) protein are also evaluated for their potential

241 irus disease 2019 (COVID-19), uses the viral spike (S) protein for host cell attachment and entry.

242 c DNA vaccine targeting the MERS coronavirus Spike (S) protein, the major surface antigen of coronavi

243 nal antibodies (mAbs) against the SARS-CoV-2 spike (S) protein.

244 that target multiple conserved sites on the spike (S) protein.

245 he HCoV-OC43 and HCoV-HKU1 betacoronaviruses spike S2, and the H1N1Ca2009 flu virus hemagglutinin.

246 ent recovery results (94-108%) obtained from spiked sage sample and from cobalamin also validated the

247 The method has been validated using spiked samples (tap water, blood serum, and saliva) and

248 e results derived with FNanoBiT assay of all spiked samples showed a strong correlation to those obta

249 were identified for three QTLs that enhance spike seed setting and grain size using gene expression

250 pore size, which leads to different average spike shapes.

251 both remediated natural soils and Pb-mineral spiked soils were reduced by >90% relative to Pb RBA for

252 ed inhibitory input drive from low-threshold-spiking somatostatin interneurons in adulthood, suggesti

253 ibly run, compare, and benchmark most modern spike sorting algorithms; pre-process, post-process, and

254 st documents community progress in automated spike sorting, and guides neuroscientists to an optimal

255 The temporal dynamics of spike spatial distribution were calculated for each pati

256 Furthermore, this enriched immunodominant spike-specific antibody profile in convalescents was con

257 ke-specific T cell responses correlated with spike-specific antibody responses.

258 Total and spike-specific T cell responses correlated with spike-sp

259 12 analyzed viral Ags, and all patients had Spike-specific T cells.

260 In the ChAdOx1 nCoV-19 group, spike-specific T-cell responses peaked on day 14 (median

261 sy." Initial EEGs were visually analyzed for spikes, spike ripples, and ripples.

262 inje simple spikes, while preserving complex spikes, suggested that eurydendroid IPSC size depended o

263 e of the 1-RBD "up" conformation in the G614 spike, suggesting increased epitope exposure as a mechan

264 comparable to or lower than that of SARS-CoV spike, suggesting that SARS-CoV-2 RBD, albeit more poten

265 ters are permanently switched on by neuronal spiking, switched off by strong hyperpolarization, and r

266 ectrodes show a slightly higher and narrower spike than disk electrodes when measuring exocytosis.

267 y 1,10-diamide substitution stabilizes Boat, spiking the temperature at which Boat and Chair can read

268 ever, that synaptic weight changes caused by spike timing dependent plasticity increase the distance

269 show that previously reported submillisecond spike timing in the avian cortex can be resolved by supe

270 yringeal muscles and that the sensitivity to spike timing increases with speed.

271 ssing windows, and providing a reference for spike timing-based codes.

272 e NAc and determined the role of GSK3beta in spike timing-dependent long-term potentiation (tLTP) in

273 We report that spike-timing dependent LTP at the synapse between PV-INs

274 total thickness of approximately 12 mm and a spiked tissue segment located in its center using transm

275 We use the Joule heating created by current spikes to trigger the insulator-to-metal transition in a

276 reaction times were preceded by enhanced STN spike-to-cortical gamma phase coupling, indicating a rol

277 a statistical method to in vivo multichannel spike trains of dorsal cochlear nucleus neurons to disen

278 In the first module, [Ca2+]i-spike trains require the concerted action of a classical

279 ope and temporal organisation of the [Ca2+]i-spike trains.

280 to reveal cell type-specific differences in spike transmission in vivo Although STP parameters estim

281 Fast-spiking units are nearly all protraction tuned.

282 n purposes, matrix effects were evaluated by spiking VGO samples with deuterated pyrene.

283 ghly context-dependent pattern of cue-driven spiking was also observed in CA3.

284 rovided a high average recovery of 91% after spiking wastewater samples with CIP at a concentration o

285 included the following: periodic discharges, spike-wave complexes, any rhythmic delta other than gene

286 Cells were characterized by spike waveform shape and firing rate.

287 ions of the N-linked glycans from the native spikes were analyzed by mass spectrometry, which reveale

288 Early morning IOP spikes were defined by a higher early morning IOP than t

289 Epileptic spikes were detected automatically.

290 the heat spike, and was buffered by the heat spike when this was the second stressor.

291 Optogenetically suppressing Purkinje simple spikes, while preserving complex spikes, suggested that

292 PAC-Ti(4)O(7) REM was tested with tap water spiked with 0.11 mg L(-1) of nine different HAAs in a si

293 an 93% after processing 7.5 mL blood samples spiked with 100 cancer cells.

294 ated by triplex labeling of a yeast proteome spiked with bovine serum albumin (BSA) over a 10-fold dy

295 Human keratinocyte conditioned media spiked with recombinant cytokines was used as an experim

296 , pretreated human plasma, and urine samples spiked with the same metabolite mixture were used and di

297 gun-proteomics workflow and applied to serum spiked with the sulfopeptides before protein dephosphory

298 by dipping swabs into synthetic nasal fluid spiked with the virus, moving the swab to viral transpor

299 b contamination and samples of clean topsoil spiked with various Pb compounds (i.e., carbonate, chlor

300 of the global glycan density of coronavirus spikes with other viral proteins including HIV-1 envelop