ライフサイエンスコーパス: spinal cord lesion

1 filtration and demyelination following focal spinal cord lesion.

2 tion of a cohort of injured CST axons past a spinal cord lesion.

3 in and the sensory and motor neurons below a spinal cord lesion.

4 can be accurately quantified within a single spinal cord lesion.

5 , or (3) four to eight brain lesions and one spinal cord lesion.

6 nsplantation of OECs into a demyelinated rat spinal cord lesion.

7 xtacortical or cortical, infratentorial, and spinal cord lesions.

8 D is related to the craniocaudal location of spinal cord lesions.

9 ught to restore neurological function across spinal cord lesions.

10 o the uncertainties about axon sparing after spinal cord lesions.

11 set significantly reduced clinical signs and spinal cord lesions.

12 ents with neurogenic bladder overactivity or spinal cord lesions.

13 vide information on the level and density of spinal cord lesions.

14 l regeneration and functional recovery after spinal cord lesions.

15 zed fibers from regenerating after adult rat spinal cord lesions.

16 large F4/80(+) macrophages/microglia in the spinal cord lesions.

17 rier (BSCB) breakdown, causing microvascular spinal-cord lesions.

18 Subjects who evolved to PPMS had more spinal cord lesions (100%) before symptomatic evolution

19 phalic, 4.3% corticospinal tract), 72.2% had spinal cord lesions (46.3% long transverse myelitis, 36.

20 ed increased sensory axon turning within the spinal cord lesion after SCI with peripheral conditionin

21 In these mice, human T cells infiltrate the spinal cord lesion and directly contact human macrophage

22 afferent axon dynamics after a laser-induced spinal cord lesion and observed massive microglia infilt

23 Despite the prevalence of cervical spinal cord lesions and atrophy, brain pathology seems m

24 they first present with clinically isolated spinal cord lesions and before they have developed sympt

25 Besides age, unequivocal presence of spinal cord lesions and being male predicted evolution t

26 elination in lysolecithin-induced rat dorsal spinal cord lesions and in slice cultures.

27 gether does not result in regeneration after spinal cord lesion, and the minimal sprouting that occur

28 y matter and white matter lesions, including spinal cord lesions, and global and regional cortical th

29 Adult Fischer 344 rats were subjected to spinal cord lesions, and the temporal and spatial expres

30 including: (i) optic nerve lesions; (ii) >=2 spinal cord lesions; and (iii) higher fulfilment of DIS

31 e, oligoclonal bands, and infratentorial and spinal cord lesions are factors associated with an incre

32 arly focal inflammatory disease activity and spinal cord lesions are predictors of very long-term dis

33 d male sex, younger age, and the presence of spinal cord lesions as independent factors that increase

34 Three-day-old rats received a cervical spinal cord lesion at C3, with or without a transplant o

35 ]; GBD 2013 0.215 [0.144-0.307]) and treated spinal cord lesions (below the neck: GBD 2010 0.047 [0.0

36 linium-enhancing (beta = 1.32, P < 0.01) and spinal cord lesions (beta = 1.53, P < 0.01) showed a con

37 iated with central pain, such as strokes and spinal cord lesions, but also disorders such as fibromya

38 ower limb motor function be improved after a spinal cord lesion by re-engaging functional activity of

39 abnormal MRI, at least three T2 brain and/or spinal cord lesions), delays time to conversion to defin

40 Spinal cord lesions detected on MRI hold important diagn

41 he local administration of LPS/IL4/IL13 into spinal cord lesion elicits profound oligodendrogenesis a

42 al areas 3b and 1 occur contralateral to the spinal cord lesion, even when <1% of labeled dorsal colu

43 of this study was to quantify axonal loss in spinal cord lesions from 5 paralyzed (Expanded Disabilit

44 ructural analyses of individual demyelinated spinal cord lesions from chronically infected mice to de

45 male preponderance, longitudinally extensive spinal cord lesions (>3 vertebral segments), and absence

46 large numbers of injured CST axons beyond a spinal cord lesion has never been achieved.

47 eas involvement of the brainstem was common; spinal cord lesions, hemisphere lesions and meningoencep

48 o [HR], 4.04 [95% CI, 2.00-8.15]; P < .001), spinal cord lesions (HR, 5.11 [95% CI, 1.99-13.13]; P =

49 mechanisms involved in scar formation after spinal cord lesion impede the design of effective therap

50 ter by surface tension, and deposited onto a spinal cord lesion in glial fibrillary acidic protein-lu

51 g DRG axons that grew toward the center of a spinal cord lesion in rats.

52 idges at the epicenter of traumatic cervical spinal cord lesions in 24 subacute tetraplegic patients.

53 Increased (18)F-FDG uptake was observed in spinal cord lesions in all diseased rats.

54 quency and characteristics of ring-enhancing spinal cord lesions in neuromyelitis optica spectrum dis

55 nal growth and functional recovery following spinal cord lesions in rodents.

56 ensory cortex after sensory loss produced by spinal cord lesions in the common marmoset (Callithrix j

57 an avenue for evaluating the distribution of spinal cord lesions in various patient groups.

58 These findings show that spinal cord lesions involve both grey and white matter f

59 , CO, USA) with acute flaccid paralysis with spinal-cord lesions involving mainly grey matter on imag

60 ts suggest that prolonged CMCT is related to spinal cord lesion load and that, over time, changes in

61 er time, changes in the CMCT occur only when spinal cord lesion load increases.

62 hown to occur largely independently of focal spinal cord lesion load, which emphasises their relevanc

63 cord cross-sectional area (UCCA), brain and spinal cord lesion loads, and brain atrophy were measure

64 nd experimental autoimmune encephalomyelitis spinal cord lesions, more specifically in reactive astro

65 e sclerosis showed a greater predominance of spinal cord lesions nearer the outer subpial surface com

66 glycoprotein 2A (SV2A) PET imaging to detect spinal cord lesions noninvasively after SCI.

67 also measured brain lesion volume, cervical spinal cord lesion number and cross-sectional area, vibr

68 um-enhancing (odds ratio 3.16, P < 0.01) and spinal cord lesions (odds ratio 4.71, P < 0.01) were ind

69 oglia treated with peptidase inhibitors into spinal cord lesions of adult mice, and found that both t

70 Evaluation of CSF and spinal cord lesions of HAM/TSP patients revealed the pre

71 ation in the brain of cuprizone-fed mice and spinal cord lesions of mice injected with lysolecithin.

72 dren had confluent, longitudinally extensive spinal-cord lesions of the central grey matter, with pre

73 The injured axons regrow into the spinal cord lesion, often traversing the injury site.

74 e presence of important risk factors for MS (spinal cord lesions, oligoclonal bands, and disseminatio

75 The presence of spinal cord lesions on the index scan and CSF-restricted

76 I model, we analyzed the effects of complete spinal cord lesions on the intrinsic electrophysiologica

77 st occur months or years following a stroke, spinal cord lesion or amputation of a limb; a previously

78 is required: (1) nine brain lesions, (2) two spinal cord lesions, or (3) four to eight brain lesions

79 hancing lesions remained significant and new spinal cord lesions over time were associated with secon

80 IS criteria including the optic nerve or >=2 spinal cord lesions performed well in PPMS diagnosis whe

81 pplication of the GSK-3 inhibitor lithium to spinal cord-lesioned rats suppresses the activity of thi

82 onance imaging of the brainstem and cervical spinal cord lesions resulting from damage to LMNs has pr

83 Systemic administration of ibuprofen to spinal cord-lesioned rodents reverses the active RhoA si

84 resence of a cellular fibroblast bridge in a spinal cord lesion site and after a growth factor stimul

85 rophin-3 (NT-3) within and beyond a cervical spinal cord lesion site grafted with autologous bone mar

86 dorsal column sensory axons extend across a spinal cord lesion site if axons are guided by a gradien

87 cellular profiles in close proximity to the spinal cord lesion site, peaking 3 d after injury.

88 prostaglandin E2 are elevated in the chronic spinal cord lesion site.

89 f other myelin-associated inhibitors, within spinal cord lesion sites in vivo.

90 e corticospinal projection within and beyond spinal cord lesion sites, achieving a major unmet goal o

91 ated axons for prolonged time periods within spinal cord lesion sites.

92 anti-scarring agent Decorin, into adult rat spinal cord lesion sites.

93 first myelitis episode was accompanied by a spinal cord lesion spanning >/=3 vertebral segments.

94 gressive multiple sclerosis; (ii) assess the spinal cord lesion spatial distribution and the hypothes

95 AT2 in AQP4-deficient regions of NMO patient spinal cord lesions supports our immunocytochemical and

96 (whole brain and gray matter), and cervical spinal cord lesions (T2LV) and atrophy.

97 Adult rats underwent bilateral dorsal column spinal cord lesions that remove the dorsal corticospinal

98 those which had previously been subjected to spinal cord lesions that transected the axons of the bul

99 However, there is little evidence for spinal cord lesions that would account for alterations i

100 ing lysolecithin-induced focal demyelinating spinal cord lesions, we found that FA synthesis is essen

101 Spinal cord lesions were localized nearest the subpial s

102 Cervical spinal cord lesions were mapped voxel-wise as a function

103 Ring-enhancing spinal cord lesions were more common in NMOSD than other

104 al bands, infratentorial lesions on MRI, and spinal cord lesions, were baseline independent predictor

105 cterized by both focal and spatially diffuse spinal cord lesions with heterogeneous pathologies that

106 enhancing, longitudinally extensive central spinal cord lesions with multifocal subcortical, basal g

107 ntifies patients with severe optic nerve and spinal cord lesions with specific pathological features