ライフサイエンスコーパス: spinal nerve

1 al consequences that follow injury to the L5 spinal nerve.

2 cord from single C-fiber afferents in the L4 spinal nerve.

3 taneous activity after transection of the L5 spinal nerve.

4 rve after ligation and transection of the L5 spinal nerve.

5 uting fibers come primarily from the injured spinal nerve.

6 e situated in characteristic regions of each spinal nerve.

7 uropathic pain induced by ligation of the L5 spinal nerve.

8 in the neural tube, or the fasciculation of spinal nerves.

9 ighboring, uninjured afferents from adjacent spinal nerves.

10 fasciculation of several cranial nerves and spinal nerves.

11 as induced by ligation of the left L(5)/L(6) spinal nerves.

12 itary chemoreceptor cells innervated only by spinal nerves.

13 nd the dorsal fin papillae are innervated by spinal nerves.

14 were removed with attached dorsal roots and spinal nerves.

15 located only on areas innervated by cervical spinal nerves.

16 duced increase in TH-IR fibres within lumbar spinal nerves.

17 pheral nerves by tight ligation of the L5/L6 spinal nerves.

18 c rats with tight ligations of the L5 and L6 spinal nerves.

19 2) that develop predominantly on cranial and spinal nerves.

20 ide, which receives both uninjured L4 and L5 spinal nerves.

21 d by conduction defects and demyelination in spinal nerves.

22 in the lumbar dorsal root ganglia and lumbar spinal nerves 14 days following continuous intrathecal i

23 oved along with the dorsal root (DR) and the spinal nerve 7-14 days after spinal nerve ligation in th

24 nd cut proximal to the previously ligated L5 spinal nerve -- a process which would transect the regen

25 trophy in brainstem, spinal cord tracts, and spinal nerves accompanied by cerebellar hypoplasia was o

26 s of the right trigeminal nerve and cervical spinal nerve afferents.

27 nerve fiber recordings were made from the L4 spinal nerve after ligation and transection of the L5 sp

28 central processes of sensory neurons (in the spinal nerve and dorsal root), ganglionic transplantatio

29 diamidino yellow) were injected into the L5 spinal nerve and DRG, respectively, the number of double

30 f sympathetic neurons projecting to both the spinal nerve and DRG.

31 ted in the dorsal root ganglion of the third spinal nerve and enter the brainstem through its dorsal

32 and requires neurogenic signaling involving spinal nerves and activation of cardiac sensory and symp

33 ed in the Schwann cell lineage in developing spinal nerves and in adult trigeminal and sciatic nerves

34 in their environment to navigate through the spinal nerves and plexus.

35 ee-dimensional T2-weighted sequence to cover spinal nerves and plexus.

36 as sensory and motoneuron axons meet in the spinal nerves and travel into the limb, sensory axons re

37 pproach that targets peripheral (cranial and spinal) nerves and utilizes their afferent pathways as s

38 ung model (i.e., tight ligation of L5 and L6 spinal nerves) and a diabetic neuropathy model (i.e., st

39 of neuropathic pain (ligations of the L5/L6 spinal nerves) and explored the relative contributions o

40 atory changes in the central nervous system, spinal nerves, and dorsal root ganglia (DRG) of rhesus m

41 , at the nerve/CNS interfaces of cranial and spinal nerves, and in somitic/intersomitic regions along

42 ateral motor column (LMC) motor axons within spinal nerves are defasciculated as they grow toward the

43 suggesting that signals from other uninjured spinal nerves are involved.

44 Following root avulsion, spinal nerves are physically disconnected from the spina

45 using all 5, 2 (C5 + C6) or 1 (isolated C6) spinal nerve as the donor nerves.

46 he compound action potential recorded in the spinal nerves, as well as the paw withdrawal threshold.

47 hold afferents proximal to the axotomized L5 spinal nerve attenuated the spontaneous activities in L4

48 aluated in axons of the sciatic nerve and in spinal nerve axons after in vivo electroporation.

49 In IB4+ spinal nerve axons, 20% of CaMKIV was colocalized with t

50 following groups of rats: (1) untreated; (2) spinal nerve axotomy (SNA), L5 SNA 1 week earlier; (3) m

51 avid lesions not only were found in impinged spinal nerves but also were associated with nonspinal ca

52 haryngeal/vagal nerve, and cutaneous rami of spinal nerves, but not by the facial nerve.

53 The ancestral long-tailed spinal nerve configuration was hypothesized from brown a

54 ells and other endoneurial components of rat spinal nerve contain serine racemase, and western blot a

55 directly supports the hypothesis that the L4 spinal nerve contributes to L5 ligation neuropathic pain

56 dystonia musculorum mouse, exhibiting rapid spinal nerve degeneration, dystonic movements, and sever

57 rimates which had a tight ligation of the L7 spinal nerve demonstrated a variety of neuropathic sympt

58 that uninjured C-fiber nociceptors in the L4 spinal nerve develop spontaneous activity after transect

59 gnathous pattern was not observed, such that spinal nerve development extends through the pygostyle r

60 ar appearance and attenuation of cranial and spinal nerve development.

61 initial position of a cutaneous axon in the spinal nerves does not strictly determine its subsequent

62 s nerves showed increased intermixing in the spinal nerves, due to errors in pathfinding and also to

63 duces regeneration, remyelination of severed spinal nerve fibres, and functional recovery.

64 nd found it important for the development of spinal nerve growth toward their muscle targets, suggest

65 h and selective trochlear and first cervical spinal nerve guidance abnormalities.

66 fibers, but not C fibers, in the injured L5 spinal nerve have been shown to develop spontaneous acti

67 ombined bilateral transection of the 'genito-spinal' nerves (i.e. pelvic, hypogastric and pudendal).

68 dance paradigm to explore the role of the L4 spinal nerve in L5 ligation nociception.

69 Ligation and transection of the L5 spinal nerve in the rat lead to behavioral signs of pain

70 tivity produced by ligation of the L5 and L6 spinal nerves in rats.

71 truncations of the ventral rami of cervical spinal nerves in the infected region.

72 iac ganglia, or on the rostral three somatic spinal nerves, in fixed specimens of the channel catfish

73 Using this spinal nerve injection approach, PEI/DNA polyplexes were

74 This study aimed to develop a spinal nerve injection strategy to deliver polyethylenim

75 vering PEI/DNA polyplexes to DRG neurons via spinal nerve injection.

76 e (ODN) was administered intrathecally to L5 spinal nerve injured rats to reduce the expression of sp

77 features of MNs following different types of spinal nerve injury (i.e., axotomy and avulsion) in the

78 site for ectopic discharge generation after spinal nerve injury and separate mechanisms seem to be i

79 Spinal nerve injury in rats increased serine-394 phospho

80 he study suggests that plasticity related to spinal nerve injury produces widespread alteration in gl

81 Our data indicated that spinal nerve injury resulted in time-dependentalpha2delt

82 At various times after spinal nerve injury, dorsal root ganglia (DRGs) from inj

83 d at both sites and in the spinal cord after spinal nerve injury.

84 All patients developed paralysis of spinal nerve-innervated muscles.

85 otor nerve guidance but is required to guide spinal nerves innervating the pectoral fins, equivalent

86 re-routing of afferent fibers from the third spinal nerve into the hypoglossal nerve.

87 d number, respectively, and migration of the spinal nerves into the forelimb bud has been modified.

88 eration, and three types of ligation on left spinal nerve (L4, L4 and L5, L5) were performed in rats.

89 Using the segmental spinal nerve (L5) ligation model of neuropathic pain, th

90 when DiI crystals were placed on the somatic spinal nerves, labeled primary afferents terminated in t

91 After peripheral nerve injury at the spinal nerve level, some axotomized afferent neurons dev

92 ically evoked responses of spinal neurons in spinal nerve ligated (SNL) rats or hindpaw levels of end

93 ked responses of spinal neurones in control, spinal nerve ligated and sham operated halothane-anaesth

94 es in control, hindpaw carrageenan inflamed, spinal nerve ligated and sham-operated rats were studied

95 responses of spinal dorsal horn neurones in spinal nerve ligated rats is reported.

96 y of post-discharge responses to baclofen in spinal nerve ligated rats.

97 d, significantly (P = 0.02) more neurones of spinal nerve-ligated (SNL) rats responded to brush compa

98 and immunohistochemical staining methods in spinal nerve-ligated neuropathic rats.

99 pression with or without dorsal rhizotomy in spinal nerve-ligated rats and its correlation with tacti

100 root ganglia (DRG) and dorsal spinal cord of spinal nerve-ligated rats with neuropathic pain, suggest

101 a in a variety of rat pain models including: spinal nerve ligation (ED(50) = 47 mg/kg, i.p.), sciatic

102 kinase (JNK) in neuropathic pain produced by spinal nerve ligation (SNL) (L5).

103 5-HT3 receptor antagonists in rats following spinal nerve ligation (SNL) but not sham operation.

104 Axonal injury by spinal nerve ligation (SNL) elevated SOCE and I(CRAC).

105 rats and in rats that had received L5 and L6 spinal nerve ligation (SNL) immediately before injection

106 p-regulated in A-fiber sensory neurons after spinal nerve ligation (SNL) in mice.

107 in 5-HT(2A)R-induced hyperexcitability after spinal nerve ligation (SNL) in rat.

108 Spinal nerve ligation (SNL) in rats significantly increa

109 on mechanical allodynia following unilateral spinal nerve ligation (SNL) in rats.

110 In this study, immunoblotting showed that spinal nerve ligation (SNL) induced a delayed and sustai

111 Furthermore, spinal nerve ligation (SNL) induced persistent neuropath

112 Spinal nerve ligation (SNL) injury in rats pretreated wi

113 ioral and neuroanatomical consequences of L5 spinal nerve ligation (SNL) injury.

114 Using the spinal nerve ligation (SNL) model of neuropathic pain, w

115 PPQ) model of acute visceral pain, and a rat spinal nerve ligation (SNL) model of neuropathic pain.

116 ty and neuropathic pain behaviors in the rat spinal nerve ligation (SNL) model.

117 dependent flush as well as the hot plate and spinal nerve ligation (SNL) models of acute and neuropat

118 20 was also studied in the rat hot plate and spinal nerve ligation (SNL) models of acute and neuropat

119 ur present study, we examined the effects of spinal nerve ligation (SNL) on the number of neurons in

120 erve injury caused by the fourth lumbar (L4) spinal nerve ligation (SNL) or chronic constriction inju

121 Spinal nerve ligation (SNL) produced expected tactile an

122 lated from neuropathic rats induced by L5/L6 spinal nerve ligation (SNL) via electrophysiological and

123 ury models: sciatic nerve transection (SNT), spinal nerve ligation (SNL), and chronic constriction in

124 mized neurons from rats made hyperalgesic by spinal nerve ligation (SNL), basal K(ATP) channel activi

125 After spinal nerve ligation (SNL), both wild-type (WT) and KO

126 C-fiber-evoked potentials in rats receiving spinal nerve ligation (SNL), but not in uninjured rats.

127 verses neuropathic pain behavior after L5/L6 spinal nerve ligation (SNL), implicating a critical func

128 olving Sprague Dawley rats, we reported that spinal nerve ligation (SNL), in addition to causing allo

129 o rat model of neuropathy, unilateral lumbar spinal nerve ligation (SNL), to characterize the distrib

130 FA)-induced chronic inflammatory pain and L5 spinal nerve ligation (SNL)-induced neuropathic pain in

131 ed protein response (UPR) activation in a L5 spinal nerve ligation (SNL)-induced rat neuropathic pain

132 in rats with mechanical allodynia induced by spinal nerve ligation (SNL).

133 rsal root ganglion (DRG) neurons after L5/L6 spinal nerve ligation (SNL).

134 scade in vivo to trigger pain behavior after spinal nerve ligation (SNL).

135 mal hypersensitivity were induced in rats by spinal nerve ligation (SNL).

136 ts in DRG neurons is downregulated following spinal nerve ligation (SNL).

137 ws or intrathecally was tested in rats after spinal nerve ligation (SNL).

138 5th lumbar (L5) dorsal root ganglia after L5 spinal nerve ligation (SNL).

139 reduced hypersensitivity in rats after L5-L6 spinal nerve ligation (SNL).

140 njury: chronic constriction injury (CCI) and spinal nerve ligation (SNL).

141 We observed that spinal nerve ligation (SNL, L5) in male Sprague Dawley r

142 L5 spinal nerve ligation did not alter the number of GABA(B

143 Spinal nerve ligation did not significantly alter alpha-

144 Spinal nerve ligation in rats significantly increased th

145 ot (DR) and the spinal nerve 7-14 days after spinal nerve ligation in the rat.

146 e not been thoroughly investigated following spinal nerve ligation in the rat.

147 -4 (TSP4), using a neuropathic pain model of spinal nerve ligation injury.

148 Sustained neuropathic pain induced by spinal nerve ligation is accompanied by D1R and met-enke

149 A modified spinal nerve ligation method was used to induce the dege

150 ing, and attenuated tactile allodynia in the spinal nerve ligation model of neuropathic pain (ED(50)=

151 reverse thermal hyperalgesia in vivo in the spinal nerve ligation model of neuropathic pain with exc

152 ciceptive responses of spinal neurons in the spinal nerve ligation model of neuropathic pain.

153 anical and thermal stimuli in vivo using the spinal nerve ligation model of neuropathic pain.

154 D50 of 8 and 5.1 mg/kg, respectively, in rat spinal nerve ligation neuropathic pain model.

155 The effect of spinal nerve ligation on alpha-CTX MII-induced mechanica

156 This study examined the effect of spinal nerve ligation on different populations of immuno

157 logical studies were performed 14-18 d after spinal nerve ligation or sham surgery, and the effects o

158 as 1, but with much lower doses, in a rodent spinal nerve ligation pain model.

159 The data suggest that spinal nerve ligation produced attenuated glutamate upta

160 Spinal nerve ligation produces a unilateral loss of alph

161 e (vector QHGAD67) 7 days after selective L5 spinal nerve ligation reversed mechanical allodynia and

162 Peripheral nerve injury in a rat model (spinal nerve ligation) of neuropathic pain triggers spro

163 nd thermal hyperalgesia in a standard Chung (spinal nerve ligation) rat neuropathic pain model.

164 utely isolated from normal rats (no previous spinal nerve ligation) responded to either mATP or ATP.

165 ivo studies in a rat neuropathic pain model (spinal nerve ligation) showed dose-dependent antiallodyn

166 cally characterized neurons in the RVM after spinal nerve ligation, a model of neuropathic pain that

167 RVM neurons were studied 7-14 d after spinal nerve ligation, and classified as "on-cells," "of

168 G was extensive as early as 2 days after the spinal nerve ligation, and the sprouted fibers were almo

169 dorsal horn was dramatically increased after spinal nerve ligation, and this was abolished by saporin

170 After spinal nerve ligation, axotomized neurons had less I(h)

171 vity was lost in the hind paw ipsilateral to spinal nerve ligation, but maintained in the contralater

172 in-43 (GAP-43) in the L5 DRG 1 week after L5 spinal nerve ligation, indicated sprouting of sympatheti

173 After spinal nerve ligation, MMP-9 shows a rapid and transient

174 ion in naive, sham-operated and neuropathic (spinal nerve ligation, SNL) rats using in vivo electroph

175 Following either sham surgery, or spinal nerve ligation, spinal muscimol inhibited Abeta-,

176 nglionic neurons was greatly increased after spinal nerve ligation, suggesting the increased number o

177 AM1241 was also active in blocking spinal nerve ligation-induced tactile and thermal hypers

178 on in the sciatic nerve of the rat following spinal nerve ligation.

179 Sprague-Dawley rats underwent left L5 and L6 spinal nerve ligation.

180 ared nerve injury, chronic constriction, and spinal nerve ligation.

181 discharges of injured sensory neurons after spinal nerve ligation.

182 lmost all ectopic discharges originate after spinal nerve ligation.

183 gesia and allodynia in the hind paw after L5 spinal nerve ligation.

184 n a rat model of neuropathic pain induced by spinal nerve ligation.

185 development of mechanical allodynia after L5 spinal nerve ligation.

186 n the absence of injury and 2 weeks after L5 spinal nerve ligation.

187 tions such as peripheral inflammation and L5 spinal nerve ligation.

188 ute to mechanical hypersensitivity following spinal nerve ligation.

189 ; AXO, partial sciatic nerve ligation; PSNL, spinal nerve ligation; SNL or chronic constriction injur

190 bset of animals also underwent unilateral L5 spinal nerve ligature to induce sustained neuropathic pa

191 dy suggests that treating uninjured adjacent spinal nerves may be used to manage chronic neuropathic

192 bundles as the axons course distally in the spinal nerves; more distally, some bundles join to again

193 ipsilateral gray rami where they entered the spinal nerves near the L4 and L5 DRG.

194 By cutting the gray rami to the spinal nerves near the lumbar sensory ganglia, we avoide

195 odel of the cranial nerves and anterior-most spinal nerves of early X. laevis tadpoles.

196 Early spinal nerves of embryos lacking the CD40L receptor (Cd4

197 e injured DRGs (defined as DRGs with injured spinal nerves) of living SNL rats.

198 by removing a small segment of the L4 or L5 spinal nerve on one side.

199 Unilateral ligation of the L4 spinal nerve or unilateral sciatic nerve ligation was al

200 ligation of the left fifth and sixth lumbar spinal nerves or streptozotocin-induced diabetic neuropa

201 ems may use the neural crest, the developing spinal nerves, or both, to establish this segmental patt

202 the number of TH-IR fibres within the lumbar spinal nerves (P < 0.01, Student's t test).

203 growing axons is an essential mechanism for spinal nerve patterning.

204 Spinal nerve projections influence auditory responses, a

205 outing from the proximal part of the injured spinal nerve (regenerative collateral sprouting).

206 Ligation of lumbar spinal nerves resulted in elevated dynorphin in the ipsi

207 Studies of potentials for dorsal spinal nerve root axons to regrow into the spinal cord i

208 ther (1) a ventral dural leak, (2) a leaking spinal nerve root diverticulum, or (3) a direct CSF-veno

209 ved by MRI imaging which demonstrated lumbar spinal nerve root enhancement and clumping or lesions.

210 nce and degree of lumbar disk herniation and spinal nerve root impingement.

211 obability of generating true tracts for each spinal nerve root of the brachial plexus, at different f

212 een identified in myelinated axons of lumbar spinal nerve roots in rabbit and rat on the basis of RNa

213 tor artemin after crush injury of the dorsal spinal nerve roots in rats.

214 Paravertebral block of the spinal nerve roots provides similar analgesia to thoraci

215 higher vertebrates is segmented to align the spinal nerve roots with the vertebrae.

216 focal axonal damage to the brainstem and the spinal nerve roots, found in 11 cases but not in control

217 rve roots in addition to the spinal cord and spinal nerve roots.

218 nflammation in the posterior spinal cord and spinal nerve roots.

219 s as axoplasmic whole mounts and delipidated spinal nerve roots.

220 ce imaging (MRI) evidence of grossly swollen spinal nerve roots.

221 G 1-20 weeks after ligation of the L5 and L6 spinal nerves, sham surgery, or no surgery.

222 length of stay compared to open surgery for spinal nerve sheath tumor resection.

223 Spinal nerve sheath tumors are slow-growing neoplasms th

224 Patients diagnosed with spinal nerve sheath tumors between 2004 and 2017 were id

225 A total of 5,968 patients with spinal nerve sheath tumors were identified: 202 (3.4%) u

226 nded LOS in patients undergoing resection of spinal nerve sheath tumors.

227 The effect of lumbar spinal nerve (SN) transection on estimates of neuron num

228 Ligation of the L5 spinal nerve (SNL) on one side in adult rats produces an

229 sham surgery or tight ligation of L5 and L6 spinal nerves (SNL).

230 njury induced through tight ligation of L5/6 spinal nerves (SNL).

231 ensitivity after acute transection of the L5 spinal nerve (SNT) in awake rats.

232 aphy (EMG) can be used to predict whether C5 spinal nerve stumps are healthy and eligible for graftin

233 city, respectively, in predicting healthy C5 spinal nerve stumps eligible for grafting were 93% (233

234 Healthy C5 spinal nerve stumps eligible for grafting with preceding

235 st in the prediction of healthy graftable C5 spinal nerve stumps in acute adult brachial plexus injur

236 t, and rhomboid EMG in predicting healthy C5 spinal nerve stumps that are eligible for grafting.

237 functional magnetic stimulation (FMS) of the spinal nerves (T1-L5) to obtain maximum expiratory funct

238 Ligation of two (L5-L6) of the three spinal nerves that form the sciatic nerve produces a par

239 ugh grafts were invaded by branches of local spinal nerves, these neurites were rarely found near ect

240 vely and the sympathetic nervous system from spinal nerves, thoracic to sacral inclusively.

241 ge spatial coverage and high resolution from spinal nerve to ankle level: four slabs per leg, each wi

242 ting along the blood vessels and cranial and spinal nerves to various parts of the meninges surroundi

243 hed a new passive transfer mouse model by L5 spinal nerve transection (L5SNT; modified Chung's model)

244 at microglial Gi DREADD activation inhibited spinal nerve transection (SNT)-induced microglial reacti

245 microglia and monocytes in a mouse model of spinal nerve transection (SNT).

246 Rats received either an L5 spinal nerve transection distal to the DRG or an L5 nerv

247 and proportion of FAAH-IR DRG occurred after spinal nerve transection injury but not after chronic in

248 histochemistry, we performed a unilateral L5 spinal nerve transection on male Wistar rats and measure

249 activation and cytokine expression after L5 spinal nerve transection or sham surgery.

250 G on mechanical allodynia associated with L5 spinal nerve transection were compared.

251 n similar to those seen following peripheral spinal nerve transection.

252 ; 15%), cranial nerves (two of 20; 10%), and spinal nerves (two of four; 50%).

253 above the known level of entry of the genito-spinal nerves was combined with bilateral vagotomy.

254 ber of TH-IR fibres within the L3, L4 and L5 spinal nerves was significantly higher in LIF-treated an

255 ligation of the left fifth and sixth lumbar spinal nerves, we found a >17-fold, time-dependent incre

256 trast agent-enhanced spinal vasculature, and spinal nerves were all well rendered alongside surroundi

257 The L(4) and L(5) spinal nerves were ligated in Sprague-Dawley rats.

258 After the L5 and L6 spinal nerves were ligated on one side, three different

259 ery, the DRGs with attached dorsal roots and spinal nerves were removed and ectopic discharges were r

260 , SNA plus loose ligation of the adjacent L4 spinal nerve with inflammation-inducing chromic gut; and