ライフサイエンスコーパス: spirometric

1 ociated with chronic respiratory symptoms or spirometric abnormalities and no evidence that the CAPS

2 Health systems in LMICs should focus on all spirometric abnormalities as opposed to obstruction alon

3 9-year cumulative incidence for spirometric abnormalities was 41.8% (number at risk: 576

4 alence estimates of respiratory symptoms and spirometric abnormalities were computed, and bivariate a

5 We assessed chronic respiratory symptoms, spirometric abnormalities, and personal exposure to air

6 igh in LAM (55%), even in patients with mild spirometric abnormalities, and was correlated with airfl

7 frequent in LAM, even in patients with mild spirometric abnormalities.

8 ss disorder [PTSD], and panic disorder), and spirometric abnormalities.

9 ents with elevated screening scores or study spirometric abnormalities.

10 change abnormality in smokers with only mild spirometric abnormalities.

11 ructive pulmonary disease (COPD) but without spirometric airflow obstruction can have respiratory sym

12 may experience respiratory symptoms without spirometric airflow obstruction.

13 improved with cyclosporine, as determined by spirometric analysis (10 events in the cyclosporine grou

14 Spirometric analysis (FEV1, FVC, VC) revealed no signifi

15 Results were combined with spirometric and anthropometric measurements.

16 Spirometric and breath-by-breath gas exchange measuremen

17 and poorly controlled HIV infection worsens spirometric and diffusing capacity measurements, and acc

18 Spirometric and IOS (resistance of the respiratory syste

19 Spirometric and IOS indices of airway function were obta

20 In this prospective study, spirometric and MDCT evaluation was done in 52 consecuti

21 For participants with asthma or COPD, spirometric and MRI measurements were repeated following

22 All daily spirometric and ventilatory changes declined in magnitud

23 Cross-sectional regression analyses using spirometric, anthropometric, and socioeconomic data were

24 Spirometric assessment included forced expiratory volume

25 A single post-bronchodilator spirometric assessment may not be reliable for diagnosin

26 p CT scan, and 2772 had at least 1 follow-up spirometric assessment, over a median of 10 years.

27 Anthropometric and spirometric assessments were undertaken.

28 ateau phase and, therefore, unlikely to show spirometric benefits.

29 or GLI-defined normal spirometry across GOLD spirometric categories.

30 for Chronic Obstructive Lung Disease (GOLD) spirometric category (1-4) on the basis of post-bronchod

31 are prevented from taking a deep breath, the spirometric changes occurring with aerosol MCh challenge

32 ommon treatment options and how clinical and spirometric characteristics affect outcomes is not well

33 It is also unclear which early spirometric characteristics identify individuals at risk

34 ssociated with any demographic, clinical, or spirometric characteristics.

35 Measurements and Main Results: Spirometric classifications using race-specific, multiet

36 For screening participants with spirometric COPD (n = 6,436), there was a twofold increa

37 ne >30 mL/mo) was evaluated by comparing the spirometric course between participants who met or did n

38 l responses in 59 participants meeting PRISm spirometric criteria (post-bronchodilator FEV(1) < 80% p

39 D and COPD severity were defined by standard spirometric criteria and symptomatic tobacco-exposed per

40 findings support consideration of expanding spirometric criteria defining COPD to include pre-BD obs

41 developing COPD who do not meet conventional spirometric criteria for airflow obstruction.

42 e of lung function and to validate the study spirometric criteria for initiation of rescue therapy.

43 tiative for Chronic Obstructive Lung Disease spirometric criteria for lung-function impairment that w

44 et into discrete physiologic groups based on spirometric criteria.

45 severity were defined according to standard spirometric criteria.

46 (20%, 60%, and 100% VC) on the basis of the spirometric data collected from each subject.

47 We retrospectively analyzed spirometric data for 197 single-lung recipients.

48 ue of stage 0-p by retrospectively analyzing spirometric data for 203 adult bilateral lung transplant

49 We have reported normative spirometric data for 3- to 6-year-old children.

50 Spirometric data revealed a mildly diminished FEV(1) and

51 Spirometric data were consistent with higher constrictio

52 Prebronchodilation and postbronchodilation spirometric data were obtained from 560 children in the

53 Acceptable spirometric data were obtained from 728 (58% boys) child

54 cerbations, adverse events, health care use, spirometric data, and high-resolution computed tomograph

55 e for 296 subjects, 188 of whom had complete spirometric data.

56 lung transplant recipients with irreversible spirometric decline and control subjects matched by time

57 IV-AAT attenuates spirometric decline in lung indexes in GOLD stage 2, a s

58 th PRM(fSAD) greater than or equal to 30% at spirometric decline lived on average 2.6 years less than

59 y the risk of death in patients with diverse spirometric decline patterns.

60 PRM(fSAD) at spirometric decline was evaluated as a prognostic marker

61 and provide prognostic information following spirometric decline.

62 r lung transplant recipients presenting with spirometric decline.

63 6% of ACO vs 10.9% of COPD alone) and severe spirometric deficits compared with participants with ast

64 ion-based studies demonstrating incidence of spirometric-defined chronic obstructive pulmonary diseas

65 often patients initially met criteria for a spirometric diagnosis of COPD but then crossed the diagn

66 To determine whether a spirometric diagnosis of mild or moderate COPD is subjec

67 We studied the spirometric effects of albuterol nebulized with heliox d

68 mphysema on CT images in individuals without spirometric evidence of chronic obstructive pulmonary di

69 rs or older when examined and who received a spirometric examination.

70 In the treatment group (n = 50) spirometric, Feno, residual volume (RV)/total lung capac

71 imitation was defined as post-bronchodilator spirometric (FEV1 /FVC) ratio <lower limit of normal.

72 Questionnaire responses and spirometric findings in participating workers were compa

73 Spirometric findings, health status, and dyspnea were al

74 studies were performed both without and with spirometric gating by using a spirometer to trigger scan

75 scanning at 90% of vital capacity (group 2, spirometric gating study).

76 tes is high and unlikely to improve by using spirometric gating.

77 agnostic performance comparable with that of spirometric GOLD staging, and provide further prognostic

78 c decline in lung indexes in GOLD stage 2, a spirometric group commonly outside current IV-AAT commen

79 ly reported COPD and a significant number of spirometric GWAS loci were at least nominally (P < 0.05)

80 GLI-defined spirometric impairment establishes clinically meaningful

81 e indicator of emphysema in subjects without spirometric impairment.

82 ween subject groups and were correlated with spirometric indexes.

83 nd no effects of prenatal supplementation on spirometric indexes.

84 llergic rhinitis (AR) and eczema, as well as spirometric indices and sensitization, were examined usi

85 In contrast, most spirometric indices from either the maximal or the parti

86 revealed evidence of gas trapping but normal spirometric indices in the cyst-positive group.

87 tion, measured by reductions in quantitative spirometric indices including forced expiratory volume a

88 ies of childhood respiratory disease whereas spirometric indices such as the FEF(25-75)/FVC ratio are

89 lly determined by reductions in quantitative spirometric indices, including forced expiratory volume

90 P = .03) but not wheezing symptoms, baseline spirometric indices, or response to bronchodilator.

91 When compared with pre-bronchodilator spirometric indices, the post-bronchodilator values demo

92 Raw were correlated with changes in several spirometric indices.

93 y described genome-wide significant COPD and spirometric loci were associated with emphysema or airwa

94 are utilization, and longitudinally, further spirometric loss, implicating cell-cell interactions or

95 and having a dog or cat) on five measures of spirometric lung function among 8- to 16-year-old subjec

96 The purpose of this study was to evaluate spirometric lung function in normal children ages 3 to 6

97 validated food frequency questionnaire, and spirometric lung function testing.

98 Derivation of regional lung spirometric maps was feasible.Keywords: MR-Imaging, MR-D

99 Forced vital capacity (FVC), a spirometric measure of pulmonary function, reflects lung

100 At the last spirometric measurement (mean [+/-SD] age, 26.0+/-1.8 ye

101 lymphangioleiomyomatosis had improvement in spirometric measurements and gas trapping that persisted

102 sing the accuracy, precision, and quality of spirometric measurements and improving the patient exper

103 Of the 14 patients who had full flow-volume spirometric measurements during infancy, 10 had FEF(25-7

104 The spirometric measurements FEV1, FVC, and the ratio FEV1/F

105 tory volume in 1 second (FEV1), representing spirometric measurements performed from childhood into a

106 A mixed-model analysis of longitudinal spirometric measurements that considered multiple risk f

107 We sought to use spirometric measurements to identify patterns of airway

108 Spirometric measurements were obtained at nursery and da

109 understanding the genetics underlying these spirometric measurements will increase our knowledge of

110 on, fraction of exhaled nitric oxide values, spirometric measurements, asthma control, and treatment

111 of obstruction, as defined by using routine spirometric measurements, can identify obstruction pheno

112 uterol, control subjects showed no change in spirometric measurements, lung attenuation, or bronchial

113 iance revealed no significant differences in spirometric measurements, maximal inspiratory pressure,

114 e excluded if study duration was <1 year, <3 spirometric measurements, or <100 subjects per arm.

115 Secondary endpoints included other spirometric measurements, pulmonary exacerbations, and h

116 study, contributing 61,746 quality-screened spirometric measurements.

117 Two loci previously associated with spirometric measures (GSTCD and PTCH1) were related to F

118 mericans [AA]) to identify associations with spirometric measures (post-bronchodilator FEV1 and FEV1/

119 Associations between spirometric measures and FEV(1) decline and mortality we

120 and further suggest that post-bronchodilator spirometric measures are optimal phenotypes for COPD gen

121 Pulmonary function was characterized by the spirometric measures forced vital capacity (FVC) and for

122 Spirometric measures from a subset of 6,425 never-smokin

123 Spirometric measures from two time points were used to c

124 ammatory response to grain dust, we compared spirometric measures of airflow and bronchoalveolar lava

125 Spirometric measures of lung function are heritable trai

126 edications, and lack of reference values for spirometric measures of lung function in many subgroups

127 Spirometric measures of pulmonary function exhibited hig

128 Spirometric measures of pulmonary function have been sho

129 rous common genetic variants associated with spirometric measures of pulmonary function, including fo

130 se studies, and its sustained improvement of spirometric measures over the 1 mo of testing in the stu

131 ight, body mass index, and smoking status on spirometric measures were adjusted through linear regres

132 The residual spirometric measures were analyzed for linkage to the ge

133 any patients have substantial improvement in spirometric measures with inhaled bronchodilator medicat

134 Associations were also observed for other spirometric measures.

135 tory volume in one second (FEV(1)) and other spirometric measures.

136 tracheal irritation, coughing, or changes in spirometric measures.

137 isoforms may regulate child lung growth and spirometric measures.

138 Lower thresholds of each spirometric metric were associated with increasing adjus

139 aged by using a 64-detector row scanner with spirometric monitoring at total lung capacity and during

140 imaged with a 64-detector row scanner, with spirometric monitoring at total lung capacity and during

141 prevalence of chronic respiratory symptoms, spirometric obstruction, and restriction were 13.6% (95%

142 Conclusions: Prepandemic severe spirometric obstruction, spirometric restriction, and gr

143 th American insulators for whom chest X-ray, spirometric, occupational, and smoking data were collect

144 sequencing) with CLD defined using clinical, spirometric, or radiographic criteria.

145 Spirometric outcomes (FEV(1), forced vital capacity, and

146 of central importance in asthma and proposes spirometric outcomes as core outcomes for all future NIH

147 rea as measured by HRCT and the mean partial spirometric outcomes were highly correlated: FEV(1)p (r(

148 sampling and were followed prospectively for spirometric outcomes.

149 pressive Regimens for management of BOS) and spirometric parameters (ie, FEV1 measurements and derive

150 e EP group was significantly impaired on all spirometric parameters (mean FEV(1) z-score, -1.08 SD [9

151 fy demographic, treatment-related factors or spirometric parameters that may be associated with respo

152 evaluated regarding post-BOS graft survival, spirometric parameters, and preceding airway infections.

153 flows, Asthma Control Questionnaire scores, spirometric parameters, peak expiratory flows, blood eos

154 a higher risk of PPCs compared with a normal spirometric pattern (adjusted odds ratio 2.64, 95% confi

155 ric pattern vs. 6.5% with a mild restrictive spirometric pattern [60 <= forced vital capacity (FVC) <

156 21.2% with a moderate-to-severe restrictive spirometric pattern [FVC < 60% predicted], P for trend t

157 dy, the impact and outcome of an obstructive spirometric pattern identified in transplant recipients

158 creased across the categories of restrictive spirometric pattern severity (6.0% with a normal spirome

159 d = 0.001) was higher across the restrictive spirometric pattern severity.

160 tients with a moderate-to-severe restrictive spirometric pattern should be regarded as high risk for

161 ometric pattern severity (6.0% with a normal spirometric pattern vs. 6.5% with a mild restrictive spi

162 d analyses, a moderate-to-severe restrictive spirometric pattern was associated with a higher risk of

163 dence of PPCs in patients with a restrictive spirometric pattern was higher than that in those with a

164 rence of PPCs in patients with a restrictive spirometric pattern was higher than that in those with n

165 y of 681 adults with a normal or restrictive spirometric pattern who were referred for preoperative e

166 was higher than that in those with a normal spirometric pattern, especially in patients with a moder

167 al population of patients with a restrictive spirometric pattern, few studies have evaluated postoper

168 tients with a moderate-to-severe restrictive spirometric pattern.

169 disease, and family studies have shown that spirometric phenotypes are heritable.

170 loci reported as genome-wide significant for spirometric phenotypes related to airflow limitation or

171 dentify genetic determinants of quantitative spirometric phenotypes, an autosomal 10-cM genomewide sc

172 We investigated whether differences exist in spirometric pulmonary function in healthy children acros

173 of chronic allograft dysfunction exhibiting spirometric, radiological, and histopathological charact

174 pulmonary disease (COPD) is defined by fixed spirometric ratio, FEV(1)/FVC < 0.70 after inhaled bronc

175 The patient had normal spirometric readings, lung volumes, diffusing capacity,

176 esidual volumes are not detected on standard spirometric readings.

177 Spirometric reference values for Caucasians, African-Ame

178 The spirometric response to standard-of-care (SOC) immunosup

179 roid does not preclude a robust clinical and spirometric response to tapering oral prednisone.

180 The prevalence of spirometric restriction was 38.6% using National Health

181 Prepandemic severe spirometric obstruction, spirometric restriction, and greater percentage emphysem

182 We carried out similar analyses for spirometric restriction, chronic cough and chronic phleg

183 Overall, we found no association of spirometric restriction, chronic cough or chronic phlegm

184 rol Test score, >19/25 or 50% increase), (2) spirometric results (FEV1 >/=80% of predicted value or >

185 FEV1, FEF25-75, and FVC were taken from spirometric results and FEF25-75/FVC ratios were obtaine

186 re classified as having CLAD on the basis of spirometric results and were divided into three groups:

187 to assess asthma control in children because spirometric results are many times normal values.

188 There was no difference in baseline spirometric results between the C-C and C-UC groups, exc

189 Spirometric results worsened most often with LDI, and ma

190 Demographic information, spirometric results, ASUI scores, and other asthma quest

191 When interpreting spirometric results, consideration of the pretest probab

192 Spirometric results, dyspnea, and health-related quality

193 of age who are able to produce high-quality spirometric results, the use of GLI-Global equations may

194 tween the two groups regarding age, sex, and spirometric results, whereas there was more profound hyp

195 3% of the subjects, whereas 33.9% had normal spirometric results.

196 re defined using questionnaire responses and spirometric results.

197 CI) 0.26-0.89), which is consistent with the spirometric results.

198 n defined by an FEV(1)/FVC ratio <0.70, with spirometric severity graded from class 1 to class 4 base

199 phan receptor gamma or alpha) increased with spirometric severity, stimulation of lung CD8(+) T cells

200 but neither correlated in concentration with spirometric severity.

201 s method is accurate, it was compared with a spirometric technique.

202 scan, and mixed ventilatory impairment in a spirometric test were revealed.

203 Spirometric tests were done at baseline, at weeks 2, 4,

204 X) has been proposed recently to be a useful spirometric tool for assessing ventilatory patterns and

205 Spirometric, total body plethysmographic, and CT data (a

206 1.13 to 0.85 and improved health status and spirometric values (P<0.001 for all comparisons with pla

207 elation [r(m)] = 0.01, P = .64) or change in spirometric values (range of r(m) values: -0.56 to -0.31

208 ds, univariate analysis demonstrated similar spirometric values and bronchodilator responsiveness in

209 After lung transplantation, spirometric values are routinely followed to assess graf

210 re was a significant but small difference in spirometric values between sitting and standing position

211 n remission differed significantly for all 3 spirometric values compared with the trajectories in tho

212 transfer abnormalities in 80.0% and abnormal spirometric values in 37.6% of patients.

213 Reduced spirometric values in first-degree relatives of early-on

214 dy in which we compared sitting and standing spirometric values in obese individuals.

215 Correlations between spirometric values or RA950 and number of pack-years wer

216 equency of exacerbations, health status, and spirometric values were also assessed.

217 or smokers and nonsmokers were compared with spirometric values, diffusing capacity of the lung for c

218 uberculosis had a negative effect across all spirometric values: FEV(1) -0.41 L (95% CI -0.51 to -0.3

219 hieved, which approach is used for reporting spirometric variables may be of low clinical significanc

220 peak to trough) of mean circadian changes in spirometric variables were 2.0-3.2% of the mesor.

221 od chest illness and within-person change in spirometric volumes between age 35 and 45 yr, adjusting