ライフサイエンスコーパス: spliced transcript

1 even epsilon553del7-CHRNE yields a normally spliced transcript.

2 produced a large amount of the alternatively spliced transcript.

3 n of a processed gene that originated from a spliced transcript.

4 sed pseudogene possibly resulting from a mis-spliced transcript.

5 plicing of a retained intron in the normally spliced transcript.

6 obe that is consistent with an alternatively spliced transcript.

7 ther depended on the sequence of the mature, spliced transcript.

8 cific patterns and some having alternatively spliced transcripts.

9 he HYDIN gene are expressed in alternatively spliced transcripts.

10 s the 3' cistron, has been found to generate spliced transcripts.

11 hows the same mutations and no alternatively spliced transcripts.

12 e 12q12 gives rise to multiple alternatively spliced transcripts.

13 R gene is expressed as several alternatively spliced transcripts.

14 but can generate at least two differentially spliced transcripts.

15 ldehyde reductase gene has two alternatively spliced transcripts.

16 veral oppositely imprinted and alternatively spliced transcripts.

17 bly assembled into a number of alternatively spliced transcripts.

18 f intron-containing RNAs to otherwise poorly spliced transcripts.

19 gh-throughput quantitation of differentially spliced transcripts.

20 (Z) locus and expresses three alternatively spliced transcripts.

21 both the cNTS and rNTS as two alternatively spliced transcripts.

22 ained transcripts are less stable than fully spliced transcripts.

23 man cDNA of about 5 kb and two alternatively spliced transcripts.

24 nd polysome association of HIV unspliced and spliced transcripts.

25 id level and generates several alternatively spliced transcripts.

26 y the expression of multiple HPV18-specific, spliced transcripts.

27 ted by the presence of several alternatively spliced transcripts.

28 kb and gives rise to multiple differentially spliced transcripts.

29 me produces constitutively and alternatively spliced transcripts.

30 ed low-magnitude upregulation of hundreds of spliced transcripts.

31 ttribute to preferential decay of aberrantly spliced transcripts.

32 d the potential interaction of alternatively spliced transcripts.

33 kipping events, which may reflect aberrantly spliced transcripts.

34 S activity in a diverse set of alternatively spliced transcripts.

35 ntron 54, decreasing the levels of correctly spliced transcripts.

36 ned within the transcriptional unit of novel spliced transcripts.

37 k genes and dynamic changes in alternatively spliced transcripts.

38 ,766 genes and 67,453 of their alternatively spliced transcripts.

39 er sequences by deep sequencing successfully spliced transcripts.

40 nor site that reduces the level of correctly-spliced transcripts.

41 A novel peptide is encoded by alternatively spliced transcripts.

42 ide (SSP), and are produced by alternatively spliced transcripts.

43 firms the presence of multiple alternatively spliced transcripts.

44 TCs) comprised the majority of alternatively spliced transcripts.

45 ding precursors of regulated or suboptimally spliced transcripts.

46 o proteins (p31 and p37) from differentially spliced transcripts.

47 y facilitate identification of alternatively spliced transcripts.

48 polymorphism in exon 4 and the alternatively spliced transcripts a and b of the CCND1 gene encoding c

49 in exon 5, with the result that incompletely spliced transcripts accumulate to high levels at the mut

50 n-containing protein, produces alternatively spliced transcripts across inbred strains of mice, and i

51 We identified an alternatively spliced transcript acted upon by both NAS and NMD, indic

52 nscriptome RNA-seq dataset, we developed the Spliced Transcripts Alignment to a Reference (STAR) soft

53 development, gives rise to an alternatively spliced transcript [alternative messenger RNA (alt-mRNA)

54 ther TNL genes, RPS6 generates alternatively spliced transcripts, although the alternative transcript

55 Ocat encodes a 5.5-kb spliced transcript and is transcribed in the opposite or

56 We report here that both the spliced transcript and its encoded protein are readily d

57 PEG1-AS is a spliced transcript and was detected as a strong 2.4-kilo

58 (2) 116 hypothetical genes had alternatively spliced transcripts and 187 genes displayed polyadenylat

59 ion, we found that a subset of alternatively spliced transcripts and 5'-extended mRNAs with NMD-elici

60 r in strain C57BL/6J results in 5% correctly spliced transcripts and a lethal phenotype.

61 iously unidentified amelogenin alternatively spliced transcripts and demonstrated that exon-8-encoded

62 Developing a full catalog of alternatively spliced transcripts and determining each of their functi

63 Alternatively spliced transcripts and exon scrambling were detectable

64 ges in coding genes, including alternatively spliced transcripts and noncoding RNAs.

65 igation described the presence of abnormally spliced transcripts and point mutations of TSG101 in bre

66 These unspliced and spliced transcripts and putative proteins encoded by SPV

67 tina-specific genes, including alternatively spliced transcripts and to prioritize candidate genes wi

68 ma1 and L(d)/Fc mu genes generated correctly spliced transcripts and were capable of secreting chimer

69 human cell lines with numerous alternatively spliced transcripts, and a full-length human coding regi

70 proteins appear to arise from alternatively spliced transcripts, and are thus identical, except the

71 ional CYP3A5*3 expression from alternatively spliced transcripts, and validation of a morpholino-base

72 Spliced transcripts (apart from the most abundant transc

73 not usually annotated as genes but produced spliced transcripts (approximately 25% success rate).

74 At least three of these alternately spliced transcripts are differentially expressed in diff

75 Two alternatively spliced transcripts are expressed, which differ in 129 b

76 Numerous alternatively spliced transcripts are generated from the gene for the

77 cSHMT proteins expressed from alternatively spliced transcripts are inactive as well.

78 r restrictions on the export of incompletely spliced transcripts are overcome by a viral protein, Rev

79 RNA sequence analysis, several alternatively spliced transcripts are significantly changed.

80 A large number of alternative spliced transcripts are synthesized from the PML gene, r

81 ential effects of a variant on alternatively spliced transcripts, as well as the difficulty in assess

82 some differentially expressed alternatively spliced transcripts belonged to myosin and myotilin gene

83 F 50a gene product (which is produced from a spliced transcript), but activates that of ORF 50b (an u

84 db/db mice also produce this alternatively spliced transcript, but with a 106 nt insertion that pre

85 ialyltransferase gene not only overexpressed spliced transcripts, but also produced high levels of un

86 lines identified nuwt transcripts, including spliced transcripts, but functionality, if any, remains

87 V1-infected mice and measured viral 757/3139 spliced transcripts by TaqMan reverse transcription-PCR

88 morphism G/A870 results in two alternatively spliced transcripts, CD1a and CD1b.

89 hat is highly transcribed in roots and whose spliced transcript constitutes a target mimic for miR171

90 S mutation (c.661-31T-->G) and alternatively spliced transcripts containing 81, 246, 358, and 523 nuc

91 ; and variants 2-5, a group of alternatively spliced transcripts containing some unique untranslated

92 xpressed (until approximately week 15), with spliced transcripts continuing to be expressed at later

93 at changes in the abundance of alternatively spliced transcripts contribute to complex trait variatio

94 An EBV LMP2A-like spliced transcript crossing the terminal repeats encodes

95 This alternatively spliced transcript, Delta7-SMN, encodes a truncated prot

96 Two alternatively spliced transcripts derived from the mH2A1 locus are res

97 teins are 91% identical, their alternatively spliced transcripts differ.

98 wever, the Delta1b and Delta1d alternatively spliced transcripts, due to deletions within the first e

99 his way reducing the number of alternatively spliced transcripts duplicate genes produce.

100 changes in RNA expression and alternatively spliced transcripts during human cortical development.

101 cancer cells, leading to the production of a spliced transcript, E6*I, of E6.

102 ESTs which derive from spliced or partially spliced transcripts either contain intron sequences or a

103 Moreover, the alternatively spliced transcripts encode proteins that lack the transm

104 The utility of this method was assessed for spliced transcripts encoded by the human Na+-K+-2Cl- cot

105 The spliced transcript encodes a protein product of 302 amin

106 Interestingly, the spliced transcript encodes a variant of gC that lacks it

107 The fully spliced transcript encodes K-bZIP, the KSHV homologue of

108 Relish, Aedes Relish has three alternatively spliced transcripts encoding different proteins.

109 on, many loci produce multiple alternatively spliced transcripts encoding proteins that may serve sep

110 There are four alternatively spliced transcripts, encoding three proteins with differ

111 These cDNAs represent differently spliced transcripts ending at different polyadenylation

112 ymocyte subsets, with the Vbeta5.1(L)-8.2(V) spliced transcript expressed earliest as well as most st

113 s in a reduction of a specific alternatively spliced transcript expressed from the early gene region

114 ressed genes and the number of alternatively spliced transcripts expressed per gene, and that the cel

115 ressed genes and the number of alternatively spliced transcripts expressed per gene, which represent

116 In addition, alternatively spliced transcripts, expressed only by the murine gene,

117 We identified an alternative spliced transcript for B-type natriuretic peptide (BNP)

118 -length open reading frames of alternatively spliced transcripts for a large number of human genes an

119 We identified alternatively spliced transcripts for both KCNE1 and KCNE3, including

120 We also identified new spliced transcripts for certain genes and evaluated thei

121 were the most frequently found alternatively spliced transcripts for REA and IF content.

122 Alternatively spliced transcripts for the S3 and alternatively polyade

123 A survey of alternatively spliced transcripts found that, in the rgh3 mutant, a fr

124 In contrast, the normally spliced transcript from wild-type CHRNE and the exon 6-s

125 A total of 166 alternatively spliced transcripts from 125 genes were significantly di

126 ected on their IF content, 269 alternatively spliced transcripts from 219 genes were differentially e

127 Our results not only show that differently spliced transcripts from a gene result in totally opposi

128 ns, (2) generates all possible alternatively spliced transcripts from expressed RNA-Seq data, (3) ana

129 binds to new binding sites on differentially spliced transcripts from genes that are linked to ALS.

130 in the human genome, including alternatively spliced transcripts from known genes and potential novel

131 ble-stranded RNAs formed by hybridization of spliced transcripts from protein-coding genes to antisen

132 by the down-regulation of the HIV-1-specific spliced transcript generating a 1.2-kbp reverse transcri

133 BACE1 proteins translated from alternatively spliced transcripts have dramatically reduced beta-secre

134 In both linear and circular mis-spliced transcripts, HNRNPM preferentially binds to GU-r

135 ase in the number of predicted alternatively spliced transcripts; however, validation of these predic

136 isoform of Erbin encoded by an alternatively spliced transcript in human tissues lacks this SID and f

137 of Met kinase that lead to an alternatively spliced transcript in lung cancer, which encodes a delet

138 An increased level of aberrantly spliced transcript in the reticulocytes of the probands

139 The first approach, RT-PCR, detected spliced transcripts in a wide range of embryonic and adu

140 s enzyme generates a number of alternatively spliced transcripts in addition to the fully spliced for

141 ome sequences yielded a set of alternatively spliced transcripts in four angiosperm genomes: three di

142 Here, the authors assess DGKalpha spliced transcripts in human LAgP neutrophils.

143 pecific differential ratios of alternatively spliced transcripts in indica rice under Cd stress, and

144 ected elevated levels of these alternatively spliced transcripts in individuals with minor spliceosom

145 quences, leading to the inclusion of falsely spliced transcripts in RNA-seq experiments.

146 accumulation of full-length yet incompletely spliced transcripts in the chromatin fraction, suggestin

147 RT show the presence of multiple alternately spliced transcripts in these tissues, corresponding to f

148 PCR) assay, we identified several abnormally spliced transcripts in which MLL exons were joined in an

149 hromatin and produces several differentially spliced transcripts, including a novel isoform, PARP-e,

150 sease gene, expression of this alternatively spliced transcript is also enhanced.

151 cterially challenged fish but only the fully spliced transcript is detectable in blood.

152 Detecting alternatively spliced transcripts is difficult when they are rare.

153 generate eQTLs when one of the alternatively spliced transcripts is preferentially targeted by the no

154 The aberrantly spliced transcript lacked 57 bases, including a second i

155 spleen exclusively express an alternatively spliced transcript lacking exon 13.

156 q-like globular domain, and an alternatively spliced transcript lacking exon 5 (EEG-1S) encodes a sig

157 gth RNA and abundant levels of an aberrantly spliced transcript lacking exon 7.

158 S7 + 2T > G allele produces an alternatively spliced transcript lacking exons 4-7, encoding an in-fra

159 reduction is due to production of aberrantly spliced transcripts lacking either exon 6 or exons 6 and

160 Alternatively spliced transcripts lacking exon 7 sequences encode a st

161 mere dysfunctional CMP identified aberrantly spliced transcripts linked to pathways relevant to MDS p

162 This alternatively spliced transcript may contribute to KSHV adaptive immun

163 nctional domains suggests that alternatively spliced transcripts may regulate Mxi1 functional activit

164 ducible antigen expression and alternatively spliced transcripts may represent additional ways of gen

165 RT-PCR analysis uncovered two differentially spliced transcripts, "mcal-A" and "mcal-B." The two tran

166 ene locus encodes at least two alternatively spliced transcripts, MCG10 and MCG10as.

167 Compared with constitutively spliced transcripts, most aberrant transcripts accumulat

168 d STING(-/-) mice had 1,350 and 80 copies of spliced transcripts/mug RNA, respectively, while no vira

169 and functional analysis of an alternatively spliced transcript of human AQP4, AQP4-Delta4, that lack

170 one spanning the 3'-UTR of an alternatively spliced transcript of SUMF1, p = 3.24 x 10(-8)), had gen

171 on concomitant induction of an alternatively spliced transcript of the cat-2 gene encoding high affin

172 differential expression of an alternatively spliced transcript of the RNA-binding protein TIAR in hu

173 We observed that the alternatively spliced transcripts of a subset of these genes, involved

174 forms are generated from three alternatively spliced transcripts of C9orf72; a long form (C9-L) and a

175 inally, reduced expression and alternatively spliced transcripts of DvABCB1 were identified in a mCry

176 Three alternatively spliced transcripts of p33ING1 encode p47ING1a, p33ING1b

177 Preliminary searches for alternatively spliced transcripts of Pcdh15 identified novel splice va

178 In contrast, one of the alternatively spliced transcripts of the bcl-x gene codes for the prot

179 hat the relative abundances of alternatively spliced transcripts of the calcium regulatory protein tr

180 We have previously described alternatively spliced transcripts of the human C2 gene.

181 Wnt gene, Wnt10a, and for two alternatively spliced transcripts of Wnt10b, as well as analyses of th

182 Alternatively spliced transcripts often encode functionally distinct p

183 euromuscular SMA phenotype is an incorrectly spliced transcript or transcripts involved in establishi

184 y leading to undetectable levels of properly spliced transcripts or the corresponding protein.

185 that express more variants of alternatively spliced transcripts per gene are those that have higher

186 ants have been compared to the alternatively spliced transcripts predicted by an EST clustering progr

187 Two alternatively spliced transcripts, psiHLAO1 and psiHLAO2, of a copper-

188 A spliced transcript putatively encoding a truncated versi

189 ue, we present EASTR (Emending Alignments of Spliced Transcript Reads), a software tool that detects

190 sly are distinct products from alternatively spliced transcripts remains to be determined.

191 These proteins are encoded by unspliced and spliced transcripts, respectively, from the p5 promoter

192 ) with absent or minute amounts of correctly spliced transcripts, respectively.

193 a novel, abundantly expressed, alternatively spliced transcript resulting from the inclusion of a 155

194 regulated because of the accumulation of mis-spliced transcripts resulting from erroneous SON-mediate

195 -untranslated region (UTR) of an alternative spliced transcript SERPINF1-012 RNA-seq analysis demonst

196 set-2 encodes two alternatively spliced transcripts, set-2(l) and set-2(s), both of whic

197 cells, and the corresponding differentially spliced transcripts show distinct expression patterns in

198 is it works in genomic space, not simply in spliced transcript space as some similar tools do.

199 e gene, HemT, that encodes two alternatively spliced transcripts specific to hematopoietic cells (Hem

200 Many tissues also produce translatable spliced transcript (SpORF2).

201 eQTL) or relative abundance of alternatively spliced transcripts (sQTL).

202 n of a third accessory protein from a doubly spliced transcript suggests that MMTV is the first murin

203 The sequence of AtCutAp encoded by the fully spliced transcript suggests that the precursor consists

204 We have identified a spliced transcript that contains sequences from the HCMV

205 tate cancer cells expressed an alternatively spliced transcript that encodes a 45-kDa glycosylated pr

206 We identified an alternatively spliced transcript that encodes a form of mouse OB-R wit

207 RNA that encodes the M1 matrix protein and a spliced transcript that encodes the M2 ion channel.

208 obrevin is encoded by a 2.5-kb alternatively spliced transcript that is found throughout the brain.

209 tients, enhances expression of an aberrantly spliced transcript that skips the preceding 101 bp exon

210 , and by identifying candidate alternatively spliced transcripts that are differentially expressed ac

211 transcripts (BARTs), a set of alternatively spliced transcripts that are highly abundant in NPC but

212 acterised by a specific set of alternatively spliced transcripts that code for proteins involved in t

213 First, we identified alternatively spliced transcripts that differ in frequency between mic

214 2 86, that are translated from alternatively spliced transcripts that differ in their 3' ends.

215 s-specific and tissue-specific alternatively spliced transcripts that encode proteins with modified c

216 sence of additional alternatively initiated, spliced transcripts that encode RTA.

217 The DPPX gene encodes alternatively spliced transcripts that generate single-spanning transm

218 tion response that upregulates alternatively spliced transcripts that have skipped offending prematur

219 yses identified a small set of alternatively spliced transcripts that may underlie environmental adap

220 r TH2 lineage consists of four alternatively spliced transcripts that regulate the expression of TH2

221 ations is the up-regulation of alternatively spliced transcripts that skip the PTC.

222 In the spliced transcript, the same sequences interact with nuc

223 To ensure specific amplification of spliced transcripts, the primers used for real-time nest

224 w that despite the presence of alternatively spliced transcripts, the protein from the fully spliced

225 The ability of alternatively spliced transcripts to encode different protein isoforms

226 genes encode a large number of alternatively spliced transcripts to produce a series of related neuro

227 and IE2(579aa), produced from differentially spliced transcripts under control of the ie1/ie2 promote

228 The major alternatively spliced transcript utilized a less favorable acceptor sp

229 In addition, an alternatively spliced transcript variant of Ptgds missing exon 3 corre

230 that overexpressed TrkB is an alternatively spliced transcript variant of TrkB (TrkBT1) with a uniqu

231 part, direct the expression of alternatively spliced transcript variants (FGF1.A, -1.B, -1.C, and -1.

232 additional transposons and produces two mis-spliced transcript variants (r15A and r15B).

233 es, 65,167 transcripts, 31,909 alternatively spliced transcript variants and 2,367 non-coding genes/n

234 robe, indicating that a stable, incompletely spliced transcript was accumulating.

235 Using this approach, an abnormally spliced transcript was identified that contains an extra

236 However, only the early multiply spliced transcript was measurably translated.

237 uman tissues revealed that the alternatively spliced transcript was present in all of the samples, an

238 ration of Xenopus oocytes, the alternatively spliced transcript was unable to promote maturation.

239 Evidence for additional alternatively spliced transcripts was obtained from de novo junction d

240 ological significance of these alternatively spliced transcripts, we expressed various transcripts in

241 anscripts were considerably less stable than spliced transcripts, we found a global stabilization of

242 Two spliced transcripts were cloned from human bone marrow a

243 Normally spliced transcripts were generally the prominent transcr

244 Many alternatively spliced transcripts were identified, including groups la

245 Several alternatively spliced transcripts were identified, including one that

246 Four alternatively spliced transcripts were identified: an extension of exo

247 Consensus and alternatively spliced transcripts were induced by lipopolysaccharide i

248 h varieties and, in some cases, incompletely spliced transcripts were observed.

249 All other alternatively spliced transcripts were rare.

250 Alternatively spliced transcripts were regulated differently throughou

251 -exon minigene, and millions of successfully spliced transcripts were sequenced after transfection of

252 press full-length mRNA and two alternatively spliced transcripts, whereas thymus and spleen exclusive

253 ied in Col-0, but not Mt-0, leading to a mis-spliced transcript which could explain the low expressio

254 ses increased expression of an alternatively spliced transcript, which encodes a previously unrecogni

255 his novel gene expresses three alternatively spliced transcripts, which encode gene products differen

256 ) splice variants, among other alternatively spliced transcripts, which is exacerbated by cool temper

257 resulting in nuclear detention of partially spliced transcripts, which may be exploited to modulate

258 is performed against both primary as well as spliced transcripts will be invaluable in elucidating th

259 Alternatively spliced transcripts with 5' variable sequences, three of

260 BDNF is generated by multiple, alternatively spliced transcripts with different 5'- and 3'UTRs.

261 human IRF5 exists as multiple alternatively spliced transcripts with distinct function(s), it is imp

262 protein annotation policy for alternatively spliced transcripts with more divergent predicted protei

263 Gtl2 encodes multiple alternatively spliced transcripts with no apparent open reading frame.

264 anscripts in CBs, which only stored nonfully spliced transcripts with retained introns.

265 o transcript analysis revealed an aberrantly spliced transcript, with intron 44 retained in the mRNA,

266 e stimulation increased the level of exitron-spliced transcripts, with optogenetic activation leading

267 This exon 2-spliced transcript would give rise to a truncated p73 pr

268 ZmHSF12 encodes two alternative spliced transcripts: ZmHSF12-1 and ZmHSF12-2; overexpres