ライフサイエンスコーパス: spontaneous breathing

1 were not significantly different compared to spontaneous breathing.

2 more rapid titration from the ventilator to spontaneous breathing.

3 tween total activity and diastolic BP during spontaneous breathing.

4 n between MSNA and diastolic pressure during spontaneous breathing.

5 ng pattern changed little after 2 minutes of spontaneous breathing.

6 ess during mechanical ventilation and during spontaneous breathing.

7 e lightly anesthetized with halothane during spontaneous breathing.

8 d retractor muscles could be measured during spontaneous breathing.

9 atients successfully completed the trials of spontaneous breathing.

10 hase, aimed to avoid derecruitment and allow spontaneous breathing.

11 n, mice were anesthetized and studied during spontaneous breathing.

12 ventilation during 7 days after the onset of spontaneous breathing.

13 range of the expiratory plume compared with spontaneous breathing.

14 g a proportional assist ventilator, PAV) and spontaneous breathing.

15 decreasing end-expiratory lung volume during spontaneous breathing.

16 the fine-scale modulations that occur during spontaneous breathing.

17 st that under supine resting conditions with spontaneous breathing: (1) R-R variability at all measur

18 dal volume during both T-piece breathing and spontaneous breathing 15 mins after extubation (p < .05)

19 expiratory diaphragmatic contraction during spontaneous breathing, 2) reduce expiratory flow and mak

20 r driving pressure (and tidal volume) versus spontaneous breathing (28.0 +/- 0.5 vs. 10.3 +/- 0.6 cm

21 flow velocity were measured during 5 min of spontaneous breathing, 30 mmHg lower body suction to sim

22 hs min-1) and volumes (0.5-1.0 l) and during spontaneous breathing across the physiological range of

23 ositive end-expiratory pressure both without spontaneous breathing activity (0.029 [0.027-0.030] vs 0

24 vs 0.044 [0.041-0.065]; p = 0.004) and with spontaneous breathing activity (0.032 [0.028-0.043] vs 0

25 e of four groups (n = 6/group; 12 hr): 1) no spontaneous breathing activity and positive end-expirato

26 ve end-expiratory pressure - 4 cm H2O, 2) no spontaneous breathing activity and positive end-expirato

27 itive end-expiratory pressure + 4 cm H2O, 3) spontaneous breathing activity and positive end-expirato

28 itive end-expiratory pressure + 4 cm H2O, 4) spontaneous breathing activity and positive end-expirato

29 Spontaneous breathing activity did not increase global l

30 ing mechanical ventilation, independent from spontaneous breathing activity.

31 er toward dependent zones in the presence of spontaneous breathing activity.

32 stomy at ICU discharge was a faster start of spontaneous breathing after tracheotomy was performed.

33 g HF-SCS is similar to that occurring during spontaneous breathing and (b) differential descending sy

34 tor-supported patients who failed a trial of spontaneous breathing and 11 patients who tolerated a tr

35 tor-supported patients who failed a trial of spontaneous breathing and 14 patients who tolerated such

36 We hypothesized that during both spontaneous breathing and controlled mechanical ventilat

37 chlieren optical system were analyzed during spontaneous breathing and different nasal high-flow rate

38 nce (bias) ranging from -54 to 612 ms during spontaneous breathing and from -52 to 714 ms during mech

39 -expiration decreased from 24% to 16% during spontaneous breathing and from 32% to 18% during control

40 ventral portion of the 3rd interspace during spontaneous breathing and HF-SCS following C2 spinal sec

41 cal use of APRV has been shown to facilitate spontaneous breathing and is associated with decreased p

42 inspiratory lung conductance (G(Li)) during spontaneous breathing and quantitative radioisotope V/Q

43 intermittent mandatory ventilation, assisted spontaneous breathing, and biphasic positive airway pres

44 ty associated with loss of consciousness, of spontaneous breathing, and of circulation.

45 tion only; and h) NVSBA group, nonventilated spontaneous breathing animals.

46 After resuming of spontaneous breathing, animals were randomly assigned to

47 During loaded spontaneous breathing, arterial pH decreased from 7.42 +

48 uld increase inspiratory tidal volume during spontaneous breathing, assessed using whole-body plethys

49 1 +/- 12 vs. -9 +/- 10 vs. -7 +/- 11 ml from spontaneous breathing at 30%, 60% and 80% W(max) , respe

50 ml min(-1) during PAV breathing compared to spontaneous breathing at 80% W(max) (P < 0.0001).

51 ed with transpulmonary driving pressure from spontaneous breathing at lower (r = 0.850; p = 0.032) bu

52 overed from respiratory failure and achieved spontaneous breathing at the same rate as younger patien

53 transdiaphragmatic pressure decreased during spontaneous breathing by >10%, 2) expiratory flow was re

54 powder synthetic lung surfactant may assist spontaneous breathing by providing noninvasive surfactan

55 who had normal lung compliance values during spontaneous breathing (C(Lspont)), C(W)/C(Lspont) was si

56 CU, the interpretation of PPV is unreliable (spontaneous breathing, cardiac arrhythmias) or doubtful

57 However, in severe lung injury, spontaneous breathing caused a significant increase in a

58 In all animals, spontaneous breathing caused pendelluft during early inf

59 groups: 1) acutely anesthetized control, 2) spontaneous breathing control, 3) spontaneously breathin

60 following ventilatory protocols for 4 hours: spontaneous breathing (control group), mechanical ventil

61 Blood flow groups were compared during spontaneous breathing, conventional mechanical ventilati

62 however, in animals with severe lung injury, spontaneous breathing could worsen lung injury, and musc

63 Analysis of patients with and without spontaneous breathing, defined by the mode of mechanical

64 ansplantation, those supported via ECMO with spontaneous breathing demonstrated improved survival com

65 tor-supported patients who failed a trial of spontaneous breathing developed a progressive decrease i

66 eper understanding of the pathophysiology of spontaneous breathing during acute respiratory distress

67 t change in tidal volume) that was caused by spontaneous breathing during mechanical ventilation.

68 In adjusted analysis, spontaneous breathing during the first 2 days was not as

69 Spontaneous breathing effort during mechanical ventilati

70 e lung protective and injurious potential of spontaneous breathing effort during positive pressure ve

71 d higher plateau pressure and more excessive spontaneous breathing effort, resulting in the highest t

72 During spontaneous breathing, expiratory diaphragmatic contract

73 nce on endogenous NK1 activation depended on spontaneous breathing frequency and the modulatory state

74 In mild lung injury, spontaneous breathing improved oxygenation and lung aera

75 In contrast, 6 hrs of spontaneous breathing in anesthetized animals did not al

76 echanical ventilation, followed by trials of spontaneous breathing in appropriate patients and notifi

77 Although these results support the use of spontaneous breathing in patients with acute respiratory

78 ury; no one has yet evaluated the effects of spontaneous breathing in severe lung injury.

79 ul tests were followed by two-hour trials of spontaneous breathing in those who met the criteria.

80 We investigated the effects of spontaneous breathing in two different severities of lun

81 During spontaneous breathing, inspiratory loading was achieved

82 n endotracheal catheter during CPAP-assisted spontaneous breathing (intervention group) or after conv

83 Spontaneous breathing is common in patients with acute r

84 While spontaneous breathing is key to weaning, excessive respi

85 Spontaneous breathing is not associated with worse outco

86 ositive end-expiratory pressure and enhanced spontaneous breathing may increase the proportion of tid

87 After 15 mins of spontaneous breathing, mechanical ventilation was instit

88 by minimally invasive methods that allow for spontaneous breathing might be safer and more effective

89 from 30 mechanically ventilated patients in spontaneous breathing mode.

90 We report that after spontaneous breathing movements are stopped by administr

91 pread was 0.99, 2.18, 2.92, and 4.1 m during spontaneous breathing, nasal high-flow of 20 L/min, nasa

92 During the trial of spontaneous breathing, O2 demand was similar in the two

93 Our findings imply that the spontaneous breathing of nucleosomal DNA together with t

94 ure spread to the amygdala may cause loss of spontaneous breathing of which patients are unaware, and

95 est that amygdala seizures may cause loss of spontaneous breathing of which patients are unaware-a co

96 ded after a weaning readiness test involving spontaneous breathing on a T-piece or low levels of vent

97 ntilation was categorized into four classes: spontaneous breathing or continuous positive airway pres

98 sure support ventilation, +2.3% (9.5) during spontaneous breathing or continuous positive airway pres

99 observed in the 7th interspace during either spontaneous breathing or HF-SCS.

100 s nonlinear P/V relationships present during spontaneous breathing or mechanical ventilation.

101 with 4-hr low tidal volume ventilation with spontaneous breathing or without spontaneous breathing (

102 The benefits of spontaneous breathing over muscle paralysis have been pr

103 Spontaneous breathing parameters showed significantly lo

104 noninvasive ventilation sessions than during spontaneous breathing periods (p < 0.05) as a result of

105 This approach was extended to the spontaneous breathing pre-extubation trial.

106 cm H2O continuous positive airway pressure, spontaneous breathing, preextubation trial when associat

107 lation with spontaneous breathing or without spontaneous breathing (prevented by a neuromuscular bloc

108 l gradients of activity were observed during spontaneous breathing prior to C2 section.

109 adjusted such that inspired volumes matched spontaneous breathing (Protocol 1).

110 During PAV breathing compared to spontaneous breathing, Q decreased by -1.0 +/- 1.3 vs. -

111 Under light anesthesia and spontaneous breathing, rats underwent UHS phase I of 75

112 We used the reduction in PET(CO2) below spontaneous breathing required to produce apnea (DeltaPE

113 without respiratory complications or without spontaneous breathing, resulting in rebreathing of gases

114 aphragm pacing and a 45-min period of loaded spontaneous breathing, separated by a 20-min recovery pe

115 cord was clamped when infants showed regular spontaneous breathing, stable heart rates greater than 1

116 es inserted near the phrenic nerves to mimic spontaneous breathing (STIM).

117 e movement greater during HF-SCS compared to spontaneous breathing, stimulus amplitude during HF-SCS

118 ction, ratings of effort were greater during spontaneous breathing than during mechanical ventilation

119 al carbon dioxide pressure (PET(CO2)) during spontaneous breathing, the apnea-hypopnea threshold for

120 During spontaneous breathing, these data were observed: minute

121 in; p = 0.0001) and the change in VO(2) from spontaneous breathing to mechanical ventilation was sign

122 H2O, and reduced the contribution of patient spontaneous breathing to total driving pressure by 57.0%

123 peptic ulcer prophylaxis (0.46 [0.38-0.57]), spontaneous breathing trial (0.81 [0.76-0.86]), family c

124 ed shorter ventilation times until the first spontaneous breathing trial (1 [0-15] vs. 9 [1-51] h; P

125 tly shorter median times to first successful spontaneous breathing trial (1.0 vs. 4.0 d; P < 0.0001),

126 e rate ratio, 1.57; 95% CI, 1.45-1.71) and a spontaneous breathing trial (incidence rate ratio, 1.24;

127 tion and an increased time to achieve a 2-hr spontaneous breathing trial (p < .0001).

128 nzodiazepine dose was associated with failed spontaneous breathing trial (p<.01) and delirium (p=.05)

129 of mechanical ventilation (MV), and greater spontaneous breathing trial (SBT) implementation.

130 management, and patient perception during a spontaneous breathing trial (SBT) might be related to ex

131 eaning failure was defined as failure of the spontaneous breathing trial (SBT) or the need for MV wit

132 Although the Spontaneous Breathing Trial (SBT) provides a measure of

133 erable controversy exists regarding the best spontaneous breathing trial (SBT) technique to use.

134 in 200 patients was analyzed in relation to spontaneous breathing trial (SBT) weaning.

135 er pressure support ventilation and during a spontaneous breathing trial (SBT).

136 ; p = 0.004) and decreased odds of passing a spontaneous breathing trial (soluble suppression of tumo

137 In patients undergoing a first spontaneous breathing trial after at least 24 hours of M

138 determined before and at the end of a 60-min spontaneous breathing trial and 4 hrs after extubation.

139 thing trial, a primary analysis included all spontaneous breathing trial and a secondary analysis inc

140 ose was independently associated with failed spontaneous breathing trial and extubation, and subseque

141 an extubation readiness testing bundle and a spontaneous breathing trial as part of the bundle met Mo

142 To assess whether lung derecruitment during spontaneous breathing trial assessed by lung ultrasound

143 t <or=25% of patients successfully completed spontaneous breathing trial but did not proceed to immed

144 ocol (n=154) underwent daily screening and a spontaneous breathing trial by respiratory and nursing s

145 patients receiving mechanical ventilation, a spontaneous breathing trial consisting of 30 minutes of

146 er extubation immediately after a successful spontaneous breathing trial is associated with clinical

147 Postextubation distress after a successful spontaneous breathing trial is associated with increased

148 End-spontaneous breathing trial lung ultrasound scores were

149 tion of aeration changes during a successful spontaneous breathing trial may accurately predict poste

150 a secondary analysis included only the first spontaneous breathing trial of each patient.

151 ot occurred despite successful completion of spontaneous breathing trial on >or=1 occasion, a rate th

152 oped acute respiratory failure (failure of a spontaneous breathing trial or successful breathing tria

153 d 1,122 (34%) patients had a full 30-120 min spontaneous breathing trial performed.

154 ty, and feasibility of protocols using daily spontaneous breathing trial plus pressure support ventil

155 Adoption and implementation of a common spontaneous breathing trial protocol across multiple int

156 oring of esophageal pressure swings during a spontaneous breathing trial provides additional guidance

157 ltrasound performed at the end of the failed spontaneous breathing trial showed a pattern consistent

158 er failed or were not yet ready to undergo a spontaneous breathing trial to automated or protocolized

159 Most respondents (96.1%) reported relying on spontaneous breathing trial to guide decision for extuba

160 The time for the first spontaneous breathing trial to occur was significantly s

161 o undertake a spontaneous breathing trial, a spontaneous breathing trial to test ventilator liberatio

162 ung ultrasound and echocardiography during a spontaneous breathing trial uncovered an unexpected caus

163 : Prompt extubation after a first successful spontaneous breathing trial was associated with more ven

164 Loss of lung aeration during the successful spontaneous breathing trial was observed only in group 2

165 or and not by the patient until a successful spontaneous breathing trial was performed or for up to 7

166 echanical ventilatory support before another spontaneous breathing trial was performed.

167 hen first meeting established criteria for a spontaneous breathing trial was significantly greater du

168 groups, and the median time to pass a 2-hour spontaneous breathing trial was similar between both the

169 Patients passing the spontaneous breathing trial were eligible for an extubat

170 Patients with hypercapnia at the end of the spontaneous breathing trial were excluded.

171 The percentage of patients undergoing a spontaneous breathing trial when first meeting establish

172 ontaneous breathing trials were analyzed, 21 spontaneous breathing trial with weaning-induced pulmona

173 Implementation of a best practice (spontaneous breathing trial) may be necessary for, but b

174 same calendar day after the first successful spontaneous breathing trial).

175 1) withholding extubation after a successful spontaneous breathing trial, 2) extubation failure withi

176 Fourteen patients failed the spontaneous breathing trial, 86 were extubated, 57 were

177 Because some patients performed several spontaneous breathing trial, a primary analysis included

178 daily screening for readiness to undertake a spontaneous breathing trial, a spontaneous breathing tri

179 patients, identifies patients earlier for a spontaneous breathing trial, and shortens the duration o

180 During spontaneous breathing trial, extravascular lung water in

181 After passing a spontaneous breathing trial, however, older patients req

182 Before and at the end of spontaneous breathing trial, we recorded pulmonary arter

183 for ideal body weight, 0.97 (0.93-1.01) for spontaneous breathing trial-induced changes in plasma pr

184 Spontaneous breathing trial-induced increases in extrava

185 determine the opportune moment to conduct a spontaneous breathing trial.

186 determine whether a patient may advance to a spontaneous breathing trial.

187 Patients passing the screen received a 2-hr spontaneous breathing trial.

188 ed within 24 hours of their first successful spontaneous breathing trial.

189 ompt extubation after their first successful spontaneous breathing trial.

190 cute brain injury who had a first successful spontaneous breathing trial.

191 either failed or did not meet criteria for a spontaneous breathing trial.

192 We performed a second 60-minute T-tube spontaneous breathing trial.

193 Twenty-one patients who failed a first spontaneous breathing trial.

194 ater than or equal to 18 mm Hg at the end of spontaneous breathing trial.

195 ty-six patients were assessed at their first spontaneous breathing trial: 63% had diaphragm dysfuncti

196 ts had 3,486 safety screens for conducting a spontaneous breathing trial; 2072 (59%) patients failed

197 d extubation within 7 days after the initial spontaneous-breathing trial, as well as reintubation wit

198 lator-free days) at day 28 after the initial spontaneous-breathing trial.

199 ress syndrome (47% vs 52%; p = 0.28) and for spontaneous breathing trials (55% vs 51%; p = 0.27).

200 r testing extubation readiness or conducting spontaneous breathing trials (B) were reported in 57%, w

201 ct of transitions of care on compliance with spontaneous breathing trials (odds ratio, 1.00; 95% CI,

202 eaning protocol incorporating daily screens, spontaneous breathing trials (SBT), and prompts to careg

203 at included a daily screen (DS) coupled with spontaneous breathing trials (SBTs) and physician prompt

204 Daily spontaneous breathing trials (SBTs) are the best approac

205 rding physicians for the completion of daily spontaneous breathing trials (SBTs) in three academic ho

206 ional parameters to determine the success of spontaneous breathing trials (SBTs) may fail to detect i

207 ated spontaneous awakening trials (SATs) and spontaneous breathing trials (SBTs) might prevent VAEs.

208 Ts)-ie, daily interruption of sedatives-with spontaneous breathing trials (SBTs).

209 akefulness is associated with the outcome of spontaneous breathing trials (SBTs).

210 extraction were measured immediately before spontaneous breathing trials and at 60 minutes after spo

211 ng protocols should be in place that include spontaneous breathing trials and criteria for initiating

212 that daily sedation interruption paired with spontaneous breathing trials improved 1-year survival, w

213 umption index increased significantly during spontaneous breathing trials in the failure group.

214 ous breathing trials and at 60 minutes after spontaneous breathing trials initiation.

215 High respiratory variability during spontaneous breathing trials is independently associated

216 Only 55% of passing spontaneous breathing trials resulted in liberation from

217 s (ie, interruption of sedatives) with daily spontaneous breathing trials results in better outcomes

218 ements were made before and 30 minutes after spontaneous breathing trials that lasted up to 60 minute

219 In primary analysis, 36 spontaneous breathing trials were analyzed, 21 spontaneo

220 venous oxygen saturation (DeltaScvO2) during spontaneous breathing trials were independently associat

221 Practices for spontaneous breathing trials were variable in 29% of Can

222 akening trials (daily sedation vacation plus spontaneous breathing trials) as a quality improvement p

223 Despite protocols incorporating spontaneous breathing trials, 31% of ICU patients experi

224 trategies with spontaneous awakening trials, spontaneous breathing trials, and early mobility and sle

225 management to spontaneous awakening trials, spontaneous breathing trials, and ICU early mobility and

226 , and 21.1% for lung-protective ventilation, spontaneous breathing trials, and neuromuscular blockade

227 prophylaxis, stress ulcer prophylaxis, daily spontaneous breathing trials, and sedative interruptions

228 edian values of respiratory variables during spontaneous breathing trials, and the change in airway p

229 at night, a practice associated with failed spontaneous breathing trials, coma, and delirium.

230 le consists of spontaneous awakening trials, spontaneous breathing trials, coordination of awakening

231 , daily screens for weaning readiness, daily spontaneous breathing trials, early resuscitation in sep

232 ther evidence-based ICU practices, including spontaneous breathing trials, ICU early mobility program

233 with three evidence-based processes of care (spontaneous breathing trials, lung-protective ventilatio

234 tions related to the methods and duration of spontaneous breathing trials, measures of respiratory mu

235 Both groups used pressure support, included spontaneous breathing trials, used a common positive end

236 and central venous oxygen saturation, during spontaneous breathing trials, were independent predictor

237 Extubation after successful spontaneous breathing trials.

238 olam, or propofol; daily sedation stops; and spontaneous breathing trials.

239 ter, less demanding ventilation strategy for spontaneous breathing trials.

240 o communicate, the following day, and before spontaneous breathing trials.

241 d weaning failure and presupposed the use of spontaneous breathing trials.

242 tolerated, coupled with daily assessment for spontaneous breathing trials.

243 nd echocardiography findings acquired during spontaneous breathing trials.

244 iochemistry exams, were collected during two spontaneous breathing trials.

245 B" for Both Spontaneous Awakening Trials and Spontaneous Breathing Trials; "C" for Choice of Analgesi

246 Spontaneous-breathing trials can be performed with the u

247 tly more ventilator-free days at day 28 than spontaneous-breathing trials performed with a T-piece.

248 s who had a high risk of extubation failure, spontaneous-breathing trials performed with PSV did not

249 c cardiac or respiratory disease) to undergo spontaneous-breathing trials performed with the use of e

250 d into 3 groups and followed up for 6 hours: spontaneous breathing ventilation (SBV, n = 5), continuo

251 phragm thickening fraction during unassisted spontaneous breathing was +17% and -14%, respectively, P

252 Effort of spontaneous breathing was assessed by the respiratory ra

253 Effort of spontaneous breathing was assessed by the respiratory ra

254 Spontaneous breathing was associated with increased vent

255 In animals with mild lung injury, spontaneous breathing was beneficial to lung recruitment

256 ndent lung inflation during paralysis versus spontaneous breathing was estimated.

257 te to tidal volume in spinally injured rats, spontaneous breathing was measured in anesthetized C2 he

258 Spontaneous breathing was present in 67% of patients wit

259 chanical ventilation, expiratory time during spontaneous breathing was prolonged less than 20% of tha

260 Assisted spontaneous breathing was the most comfortable mode of v

261 at the level of support we imposed, assisted spontaneous breathing was the most comfortable mode of v

262 Patients with spontaneous breathing were older and had lower acute res

263 hout acute lung injury, and the influence of spontaneous breathing with continuous positive airway pr

264 % during four breathing patterns compared to spontaneous breathing, with the greatest changes during