ライフサイエンスコーパス: spotlight

1 curated in this retrospective cohort study (SPOTLIGHT).

2 regulator of autoimmunity has come into the spotlight.

3 oncept of adenovirus oncolysis back into the spotlight.

4 ut is inconsistent with a simple attentional spotlight.

5 dvanced and landed interferons (IFNs) in the spotlight.

6 , potential hydrogen exporters move into the spotlight.

7 neurophysiological proxy of the attentional spotlight.

8 lling for different sizes of the attentional spotlight.

9 eceptor tyrosine kinase ligand bias into the spotlight.

10 are propelling mental health into the global spotlight.

11 elivery systems for phytochemicals are under spotlight.

12 ent events have pushed RNA research into the spotlight.

13 ing of 6mA in eukaryotes, 6mA is back in the spotlight.

14 demic has put the clinical laboratory in the spotlight.

15 c thrust the field of public health into the spotlight.

16 velopment plans for the region back into the spotlight.

17 ced Raman spectroscopy (TERS) now enters the spotlight.

18 e 2-foci division of attention or a circular spotlight.

19 nued unabated albeit largely out of the main spotlight.

20 l modeling have kept surface plasmons in the spotlight.

21 ended effects is just coming to the national spotlight.

22 st, we applied global metabolic profiling to spotlight 32 metabolites whose uptake or secretion kinet

23 acquisition time of 0.062 s per pixel with a Spotlight 400, PerkinElmer) and 64-scan (acquisition tim

24 an (acquisition time of 4 s per pixel with a Spotlight 400, PerkinElmer) infrared images, two deep le

25 The results spotlight a major role for pol V and minor roles for pol

26 ings from the conference attendee survey and spotlight a new disability support grant from the Britis

27 tation causes sensitivity to iron depletion, spotlighting a critical role for GrxD under conditions t

28 and facilitates its proteolytic degradation, spotlighting a novel step that potentially modulates Wnt

29 ough in situ crystallographic analysis while spotlighting a rare metastable crystalline phase.

30 Collectively, this review spotlights a diverse body of research examining an often

31 overning the RSV entry machinery, this study spotlights a molecular mechanism of broad RSV resistance

32 Our comprehensive study spotlights a previously unrecognized clock component of

33 onstruction of a phytopathogenic microbe, we spotlight an unusual respiration machinery as a potentia

34 nformation being pulled into the attentional spotlight and bestowed with enhanced processing.

35 e dramatic events drew PML squarely into the spotlight and generated considerable interest from the m

36 ty and food security are increasingly in the spotlight and increasingly intertwined.

37 , the agent learned to control its attention spotlight and learned the catch task.

38 hidden part of the blood proteome via novel SpotLight approach.

39 This spotlight article discusses recent advances, mechanisms

40 This Spotlight article discusses some of the dominant themes

41 This Spotlight article discusses the different factors that a

42 This Spotlight article is a commentary on the early nuclear t

43 This Spotlight article looks at the original rationale behind

44 In this spotlight article we discuss the broader context for the

45 This Spotlight article will describe the state of progress of

46 In this Spotlight article, Meritxell Huch and Juergen Knoblich b

47 In this Spotlight article, we advocate a developmental biology t

48 In this short Spotlight article, we define the breadth and expected im

49 In this Spotlight article, we discuss these species-specific dif

50 In this Spotlight article, we provide an overview of some of the

51 In this Spotlight article, we review the current understanding o

52 In this short Spotlight article, we summarise advances and challenges

53 ts have emerged, and D4 is once again in the spotlight as a novel target for both addiction and Parki

54 Messenger RNA vaccines have come into the spotlight as a promising and adaptive alternative to con

55 al complications brought this virus into the spotlight as causing an infection of global public healt

56 s ATP factories, mitochondria have taken the spotlight as important regulators of cellular homeostasi

57 Glia have moved into the spotlight as participants in synaptic signaling.

58 Micro-ribonucleic acids (miRNAs) are in the spotlight as post-transcriptional regulators of gene exp

59 Such markets have been in the spotlight as sources of zoonotic viruses, for example, a

60 ular; drug-responsive T cells, firmly in the spotlight as the mediators of these reactions.

61 re in the SARS-CoV-2 spike protein, has been spotlighted as a factor key to facilitating infection an

62 nome are highly conserved and have thus been spotlighted as a promising therapeutic target to combat

63 dielectric-metal structure has recently been spotlighted as a superior platform for strong light-matt

64 ased extracellular serotonin, and points the spotlight at a potentially critical player in the pathol

65 nd environmental crises were recently in the spotlight at a United Nations (UN) conference in Qatar.

66 wever, that targeting AXL has come under the spotlight because of ever accumulating evidence of its s

67 class of materials that have been under the spotlight because of their diverse structural varieties

68 Here, we spotlight both the promise and the urgency of a converge

69 analysis, we present a Python package named Spotlight, building on established Rietveld packages suc

70 This issue has been pushed into the spotlight by recent clinical trials of new technologies

71 s from the Ipc seem to act as an attentional spotlight by selectively boosting the propagation of ret

72 automated imaging of multiple specimens, as spotlighted by a quantitative multi-scale analysis of br

73 ut pulmonary research firmly into the global spotlight, challenging previously held notions of respir

74 Our findings spotlight cloud-surface coupling as a key factor for ACI

75 onally conceptualized as a static continuous spotlight, contemporary models of attention highlight it

76 ever, put TRP channels and astrocytes in the spotlight, describe their ability to modulate the activi

77 This Spotlight discusses the state of current in vitro model

78 on T cell receptors (TCRs) are under recent spotlight due to the growing appreciation of the roles o

79 Polymer solar cells have been spotlighted due to their potential for low-cost manufact

80 Once obscure, the cilium has come into the spotlight during the past decade.

81 We spotlight emerging techniques and approaches employed in

82 This Spotlight examines the role of ASCT in the era of novel

83 Notably, in Alzheimer's disease, GLTD spotlights extremely long synaptic genes at chromosomal

84 This Spotlight focuses on new knowledge of the role of Escher

85 In this Spotlight, focusing on microcephaly as a case study, we

86 by bringing tRNA-based therapy back into the spotlight for future investigations to assess the effica

87 Recent advances bring TCF1 into the spotlight for its versatile, context-dependent functions

88 inogen activation has traditionally held the spotlight for many decades as the central pathogenic eve

89 irculating tumor DNA (ctDNA) has been in the spotlight for the last decade, less is known about circu

90 chalcogenides (TMDs) have been placed in the spotlight for their advantageous properties for catalyti

91 cells, basophils have recently come into the spotlight for their role in the initiation of Type-2 imm

92 ion and computational prediction models, are spotlighted for their potential to revolutionize polydie

93 We developed a reporter, SPOTlight, for brainwide imaging of ISR state with cellu

94 ew study of anther lobe formation shifts the spotlight from epidermal wall extensibility to the elast

95 Spotlight further enables the efficient design of refine

96 The metaphor of the "spotlight" has long been used to describe spatial attent

97 derpinnings of the locus of this attentional spotlight have been relatively well studied, less is kno

98 Overall, we spotlight how the balanced production of distinct member

99 Taken together, our results spotlight how widespread gene duplications can provide m

100 ental questions emerged and are still in the spotlight: how bacteria organize their chromosomes to fi

101 arning architectures frequently captures the spotlight; however, the significance of specimen process

102 In this Spotlight, I highlight the opportunities for development

103 In this Spotlight, I provide my perspective on the events that o

104 Chemical interrogation spotlights IAV HA as a major druggable target for small-

105 MIPs came into the spotlight in 1993 when they were dubbed "antibody mimics

106 sting existence in obscurity into the bright spotlight in cell biology and medicine.

107 des B cells have increasingly moved into the spotlight in multiple sclerosis (MS) research.

108 ntion, tracking a stimulus with an attention spotlight in order to solve a catch task.

109 veral decades ago, uromodulin has gained the spotlight in recent years, since the discovery that muta

110 Peroxynitrite has come into the spotlight in recent years.

111 dy of literature brings these enzymes to the spotlight in the field of virology.

112 o regulate the rates of iron absorption, the spotlight in the past decade has been placed on the syst

113 chiatric illness, increasingly in the public spotlight in the United States due its prevalence in the

114 ndemic has thrust immunology into the public spotlight in unprecedented ways.

115 s, then, through synchronization, they would spotlight information that may be critical for control o

116 ns were investigated: (1) does splitting the spotlight into multiple foci incur an overhead cost that

117 SPOTLIGHT is a global, randomised, placebo-controlled, d

118 The spotlight is now on dysfunctional adiposity as a precurs

119 The spotlight is now shifting to the phosphatidylinositide 3

120 The spotlight is now shifting towards emphasizing both focal

121 Then the spotlight is shone on the sophisticated fabrication meth

122 The focus of this Spotlight is to showcase the rich plant fossil record op

123 Although CaMKII may have taken the spotlight, it is a member of a large family of diverse a

124 fective organelles, has entered the research spotlight largely owing to the discovery of the protein

125 The surprising efficiency of the multiple spotlight mechanism supports the emerging view that spat

126 across the same spatial extent, the multiple spotlight mechanism, which ignores intervening stimuli,

127 This Essay spotlights methodological innovations that have enabled

128 but our findings transcended these regions, spotlighting modifications dispersed across a gamut of c

129 ed the way for certain polymers to be in the spotlight, namely sequence-defined polymers such as mess

130 ed the same number of stimuli, splitting the spotlight neither impaired performance nor diminished BO

131 ase and ribonucleotide reductase, while also spotlighting new enzymes, such as the mitochondrial prol

132 Sirtuin 6 (SIRT6) has been in the spotlight of aging research because progeroid phenotypes

133 stics acquired under a peripherally deployed spotlight of attention are systematically biased by sacc

134 in gaze localization, we have shown that the spotlight of attention at this scale can reach a strikin

135 responsive neurons corresponds to the mental spotlight of attention via modulation of ongoing visual

136 a sources, one of which reflects the "visual spotlight of attention" and the other reflects attention

137 opagate through the cortex, by generating a "spotlight of attention".

138 could signal the arrival of gaze (and/or of spotlight of attention) in a new position in the periper

139 ulated by attention representing the "visual spotlight of attention." By contrast, a parietal alpha s

140 LD is in the cross-spotlight of cognitive neuroscience and sleep research a

141 day, where 2D halide perovskites are in the spotlight of current research, offering characteristics

142 inflammatory diseases and has moved into the spotlight of drug discovery.

143 f MS patients, bringing NK cells back to the spotlight of MS pathology.

144 n be produced with kits are currently in the spotlight of radiopharmacy and nuclear medicine.

145 his newly proposed treatment has been in the spotlight of the lay public, the popular media, and the

146 nanomaterials and nanocomposites are in the spotlight of the search for novel concepts for integrati

147 ic nuclei play a key role in controlling the spotlight of visual attention.

148 al neurons, and thus redistribution of local spotlights of activity in neocortical circuits, while pr

149 The results failed to support a unitary "spotlight" of attention.

150 assignment is guided by the location of the "spotlight" of selection, where the selected region becom

151 sponses to all stimuli that fall within the "spotlight" of spatial attention, whether or not the stim

152 in artificial intelligence (AI) places a new spotlight on a long-standing question: how can we best d

153 ng data, both in mice and in humans, put the spotlight on a new subset of T helper (Th) cells, in par

154 of chemokine receptors in disease have put a spotlight on atypical chemokine receptor 3 (ACKR3).

155 The recent regulatory spotlight on continuous monitoring (CM) solutions and th

156 using macromolecular approaches, including a spotlight on cutting-edge materials that respond to envi

157 Single-cell approaches have shone a spotlight on discrete context-specific tissue macrophage

158 Our aim is to put a spotlight on distinctive molecular features in a field t

159 eve this dream, which has cast a significant spotlight on elite soccer players who possess exceptiona

160 and asymptomatic individuals has turned the spotlight on healthcare interventions that involve aeros

161 issue of Blood, Hassan et al have turned the spotlight on hematopoietic stem cell transplantation (HC

162 We shine a spotlight on his seminal work describing how the innate

163 This puts a spotlight on holographic methods for the quantitative mo

164 We shine a spotlight on how this work has inspired the development

165 logical advances, it is anticipated that the spotlight on HSP, alone or in combination with other str

166 Further putting a spotlight on IDRs are recent discoveries of functionally

167 This article casts a clinical spotlight on important challenges and dilemmas encounter

168 The effect of ASAP1 on actin dynamics puts a spotlight on its function as a central signaling molecul

169 The COVID pandemic has put a spotlight on laboratory medicine, showcasing how vital d

170 A lively musical shines a stylized spotlight on Marie Curie's extraordinary life.

171 The present review throws a spotlight on new and emerging food safety concerns in vi

172 iew of senescence in fracture healing with a spotlight on osteoimmune cross-talk provides a promising

173 This event placed a spotlight on recent intense (exceeding Category 4 or 5 o

174 egal system and certainly cast a much-needed spotlight on scientific evidence in the courtroom.

175 repreneurship and place, I demonstrate how a spotlight on stability illuminates a resolution to the m

176 This Review puts the spotlight on such cyclophanes, illuminating both the che

177 This collaborative review shines a spotlight on technologies that will be crucial to interr

178 Here we shine a spotlight on the calcitonin and PACAP (PAC(1)) receptor

179 ad to more robust humoral immunity has put a spotlight on the capacity for early antibodies to augmen

180 The COVID-19 pandemic is shining a spotlight on the field of immunology like never before.

181 Furthermore, we place a spotlight on the increasing importance of DOSY NMR being

182 By doing so, we aim to put the spotlight on the most important element of glycobiology:

183 el epidemics of obesity and diabetes shine a spotlight on the potential for therapeutic manipulation

184 deeply-rooted daily patterns but also put a spotlight on the role of computational modeling in scien

185 Recent studies have put the spotlight on the wide gap between the complexity of Tau

186 Here we put a spotlight on their mechanisms of action, studies that le

187 In the last section of this review, we put a spotlight on this burgeoning area of microglial research

188 In this Focus Review, we put the spotlight on very recent insights into the fascinating w

189 With the spotlight on work, one might wonder where all the occupa

190 phosphorylation of histones has been in the spotlight only recently.

191 overt attention as a limited resource, zoom, spotlight, or weighting of visual information.

192 y fractured horizontal wells has been in the spotlight over the last ten years because of the signifi

193 ningeal immunity has recently come under the spotlight owing to the characterization of meningeal lym

194 ne interactions, has recently come under the spotlight owing to the characterization of meningeal lym

195 Bile acids are increasingly appearing in the spotlight owing to their novel impacts on various host p

196 We spotlight possible explanations for and consequences of

197 Our findings spotlight potential susceptibility loci within circadian

198 late-stage fluorination strategies, with the spotlight primarily focused on single-atom modifications

199 The low added burden of SpotLight proteome analysis makes it attractive for use

200 th the zoom lens, and (2) does splitting the spotlight provide a benefit relative to the zoom lens by

201 This Spotlight provides an accessible introduction to single-

202 rather than fueling unquestioning decisions, spotlighting punishers' decision-making processes may en

203 The goal is to spotlight recent advancements, identify common themes, a

204 olated multivariate brain asymmetry patterns spotlighted regions typically thought to subserve latera

205 This review spotlights research related to ethical and unethical beh

206 This spotlight review focuses on the second-generation immuno

207 This spotlight review focuses on the second-generation protea

208 This Spotlight review highlights such factors and their emerg

209 iverge from the experimental setup staged to spotlight satellite cells.

210 ormation supports public health decisions by spotlighting segments of the population where outbreaks

211 grees of freedom in a deformed molecule, and spotlight selected applications of quantum mechanochemic

212 This study spotlights several important considerations in DNA cryst

213 al attention has often been analogized to a 'spotlight' shining on the item of relevance.

214 We spotlight specific examples that have facilitated and en

215 ht, with subsequent interference of followed spotlight, stroboscopic illumination, high-temperature s

216 Here, we report findings from the SPOTLIGHT study (NCT04186845), assessing the performance

217 h invertebrate and vertebrate animals, while spotlighting success and potential for bio-inspired manm

218 Summary: This Spotlight summarizes conclusions from The Company of Bio

219 eed for efficient energy storage systems has spotlighted supercapacitors and nanostructured porous ca

220 This Spotlight synthesises key concepts emerging from recent

221 tention has long been postulated to act as a spotlight that increases the salience of visual stimuli

222 onceptualize spatial attention as a blinking spotlight that sequentially samples visual space.

223 viable therapeutic target in HER2(+) LC and spotlight the benefits of targeting the tumorigenic tran

224 Then, we spotlight the complexity of organellar (i.e., mitochondr

225 Although not yet approved worldwide, here we spotlight the current data for imetelstat and where it m

226 These data show that crossreactive TCRs can spotlight the evolutionarily conserved features of TCR-M

227 ulatory and developmental diversity but also spotlight the HNF+ subtype's reliance on FGFR signaling.

228 discrimination are widespread, our findings spotlight the importance of drawing people's attention t

229 We also spotlight the key evidence for underappreciated XPO1 fun

230 identify key gaps in each of these areas and spotlight the need for more research bridging molecular

231 ising palm oil demands in sub-Saharan Africa spotlight the need to consider informal economies when i

232 To contextualize these mechanisms, we spotlight the nervous system, a tissue enriched in regul

233 Subsequently, we spotlight the potential of enzymes, in particular, polys

234 Preliminary clinical data spotlight the stomach as a potential dose-limiting organ

235 We spotlight the structural principles identified in ECMs,

236 re for veterans with advanced kidney disease spotlight the substantial challenges of cross-system use

237 entful trends observed for RNase k6 serve to spotlight the unique nature of EDN and ECP and the unusu

238 ucture-function relationships of enzymes and spotlight the use of NMR spectroscopy and MD simulations

239 e Tools and Resources for the Community," we spotlight the work of several BRAIN investigator teams w

240 e proteins by x-ray crystallography and have spotlighted the critical need for alternative approaches

241 Pathway analysis spotlighted the significance of these genes in processes

242 ria, effective treatments are still limited, spotlighting the need for investigation of the neural su

243 activation driven by PI3Ka driver mutations, spotlighting the PI3Ka double (multiple) activating muta

244 vation driven by PI3Kalpha driver mutations, spotlighting the PI3Kalpha double (multiple) activating

245 By spotlighting the roles of socioecology and genetics, our

246 The story spotlights the actions of a charity in the transition fr

247 This review spotlights the Babesia duncani in culture-in mouse (ICIM

248 Our investigation spotlights the interplay between genetic variation and s

249 Our work spotlights the lasting effects of social injustices on t

250 This review article spotlights the principle of DIC with its effect on vitam

251 the dual nature of biomolecular condensates, spotlighting their role in cancer, particularly concerni

252 kinetics, and chemical/radiolytic stability spotlight this hydrophilic class of ligands as exception

253 dal anti-inflammatory drugs have been in the spotlight this year.

254 kely to emerge from the shadows and into the spotlight to elucidate how the somatic mutation of antib

255 also speed up enzymatic turnover--turning a spotlight to the fact that its actual role in enzymatic

256 sing a seeded nonnegative matrix regression (SPOTlight) to deconvolute the dynamic landscape of cell-

257 open-source computational tools, Giotto and SPOTlight, to increase resolution and measure cell-cell

258 studied, less is known about the size of the spotlight: to what extent can the attentional field be b

259 t of the literature on this topic shines the spotlight toward melanocytes, the focus of this paper is

260 This tutorial review turns the spotlight towards mechanochemical research in the field

261 We report the results of the SPOTLIGHT trial, which investigated the efficacy and saf

262 ng such tasks: the "zoom lens" and "multiple spotlights." Two key questions were investigated: (1) do

263 Three spotlights underpin this debt: 1) a severe contrast in d

264 This finding of two spotlights was obtained within a single cortical hemisph

265 In this Spotlight, we argue that, as developmental biologists, w

266 In this Spotlight, we describe the achievements by developmental

267 In this brief Spotlight, we describe the developmental significance of

268 In this Spotlight, we draw together insights and proposals discu

269 In this Spotlight, we explore recent in vivo findings, primarily

270 In this Spotlight, we focus on the role of HDTFs during embryoge

271 In this Spotlight, we hear first-hand accounts from five scienti

272 In this brief Spotlight, we highlight some of the technical developmen

273 In this spotlight, we highlight this important advance in the fi

274 In this short Spotlight, we present the mechanisms generating bi- and

275 In this Spotlight, we provide a historical perspective and a non

276 In this Spotlight, we provide an introduction to machine learnin

277 In this spotlight, we review technical issues that compromise si

278 In this Spotlight, we will discuss the recently described compli

279 synuclein gene family recently came into the spotlight, when one of its members, alpha-synuclein, was

280 Nitric oxide is back in the spotlight with a new series of studies showing that it p

281 ard a specific biological target, shares the spotlight with an emerging and alternative polypharmacol

282 olism of bacteriophage T4 has moved into the spotlight with its clear mechanistic precedents.

283 We demonstrate Spotlight with the analysis of uranium molybdenum and Ti

284 described, the crystalloids are back in the spotlight, with recent discoveries pointing to an import