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1 ions (i.e., licking either a left or a right spout).
2 citric acid, quinine, and water) from a lick spout.
3 monitored by a capacitive touch-sensor water spout.
4 ock (0.35 mA) on Day 5 after approaching the spout.
5 gue kinematics in mice drinking from a water spout.
6 resulted in hypometric licks that missed the spout.
8 ced with a water reward but responses to the spout after a negative conditional stimulus (CS-) were n
9 nd the ratio of air flow rate to the minimum spouting air flow rate (Q)) on the residual enzyme activ
11 rtheless, most biological assays of vascular spouting are conducted in a static mechanical milieu.
16 in nonessential behaviors (e.g., licking on spouts beyond the period of reward delivery) and were sl
18 mesolimbic dopamine signals during the multi-spout brief-access task that display strong correlations
19 Belize, Central America, has yielded several spouted ceramic vessels that contain residues from the p
21 ry similar to the conserved core fold of the SPOUT-class methyltransferases but contains a novel exte
25 Herein, we describe current knowledge of SPOUT enzyme structure, domain architecture, and key ele
26 the process of substrate recognition by the SPOUT enzymes will be critical for defining many facets
27 ossessing the trefoil knot characteristic of SPOUT enzymes, Trm10 does not share the same quaternary
28 (such as cabbage, cauliflower, and brussels spouts), exhibits antitumor effects through poorly defin
29 e or key sequences with other members of the SPOUT family, suggesting a novel mechanism of catalysis.
30 that YOR021C is the first known MTase with a SPOUT fold that methylates a substrate other than RNA (p
33 imbic areas as rabbits learned to approach a spout for water reinforcement after a tone (CS+) and to
34 Here we show that mice trained to lick a dry spout in order to receive intra-gastric infusions of a f
35 e obtain a sugar water reward if they lick a spout in the presence of the rewarded odorant and avoid
36 The entrained particles eventually cause the spout interface to break, producing a thin coat of contr
38 L30e-like amino-terminal domain (NTD) and a SPOUT methyltransferase family catalytic carboxyl-termin
39 s and the discovery of the dependence of one SPOUT methyltransferase on metal ion binding for catalys
40 th a new sequence alignment that divides the SPOUT methyltransferase superfamily into four major clad
42 et)-dependent alpha/beta-knot superfamily of SPOUT methyltransferases (MTases), with a high structura
46 erestingly, Yor021c belongs to the family of SPOUT methyltransferases that, to date, have only been s
47 member of the alpha/beta-knot superfamily of SPOUT MTases in the RlmH or COG1576 family with bound Ad
55 ferase (Trm10) is a member of the SpoU-TrmD (SPOUT) superfamily of methyltransferases, and Trm10 homo
56 ingual kinematics as mice drank from a water spout that unexpectedly changed position during licking,
57 ponses yielding oral contact with a drinking spout that was inserted into the conditioning chamber af
60 or fatty acids of residues from three small, spouted vessels that were found in Bronze and Iron Age g
61 aracteristics and structures of the original spouting vessels (stalks) from the choroid, polypoidal s
62 Transanal resection of an elongated IPAA spout was performed on 58 patients; abdominoperineal mob
63 n was apparent, and after 4 weeks, extensive spouting was observed throughout the entire dorsal horn,
65 ch task, ferrets were rewarded for licking a spout when they heard a target tone amid a sequence of r
66 to associate tastants sampled from a central spout with different actions (i.e., licking either a lef