ライフサイエンスコーパス: stabilization

1 ing reduced to half after a period of weight stabilization.

2 involved in T cell activation-dependent mRNA stabilization.

3 and biochemical (serum calcium, calcitriol) stabilization.

4 DAC development in the absence of robust p53 stabilization.

5 pm binding affinity, consistent with overlap stabilization.

6 mechanism for HC.HA cross-linking and matrix stabilization.

7 migrated to oil-water interface for emulsion stabilization.

8 ombinational DNA repair and replication fork stabilization.

9 ltered despite apparent systemic hemodynamic stabilization.

10 se deficits can be attenuated by microtubule stabilization.

11 as a prerequisite for the intersubunit cross stabilization.

12 ctions such as nutrient cycling and sediment stabilization.

13 en, which could explain hypoxia-induced IRP2 stabilization.

14 ions and demonstrate the need for pump laser stabilization.

15 le-shot readout of the protected qubit under stabilization.

16 ptic plasticity is necessary for place field stabilization.

17 actin and the EB1, which is important for MT stabilization.

18 sis, activity decreases to ensure attachment stabilization.

19 gical p38 inhibition resulted in Osx protein stabilization.

20 ling strong enough to require inhibition for stabilization.

21 through early adulthood followed by disease stabilization.

22 ghlighting the importance of the macrocyclic stabilization.

23 main are important for FBXL16-mediated C-MYC stabilization.

24 tion, triphosphate binding, and RNA template stabilization.

25 duced cell survival, as a consequence of MYC stabilization.

26 stabilizer, thus perfecting transition-state stabilization.

27 role in dendritic arbor and dendritic spine stabilization.

28 ticles is an important parameter in oil foam stabilization.

29 the foundation for subsequent selection and stabilization.

30 lectivity through selective transition state stabilization.

31 by promoting TSC1-TSC2 dimerization and TSC2 stabilization.

32 microbial processes, and soil organic matter stabilization.

33 entation of a personalized approach for mood stabilization.

34 in the ipsilateral axon, to prevent Hebbian stabilization.

35 ponses, prosurvival, and endothelial barrier stabilization.

36 lagens leading to extracellular matrix (ECM) stabilization.

37 ct interactions with RNA resulting in mutual stabilization.

38 r improves phenotypes associated with G4-DNA stabilization.

39 y the PPsome complex also contribute to mRNA stabilization.

40 d instrument, (2) lung function optimization/stabilization, (3) patient/provider agreement regarding

41 iation with microtubule ends and microtubule stabilization [6, 7].

42 the inter-ring angle and the extent of LUMO stabilization about the diketophophanyl scaffold.

43 progression of fundus alterations and their stabilization after disease remission.

44 /d diet for 8 wk, followed by 4 wk of weight stabilization and a 9-mo weight loss maintenance program

45 entifies DINO as a critical mediator of TP53 stabilization and activation in HPV16 E7-expressing cell

46 allizable fragment (Fc) domain for increased stabilization and avidity, the most optimal ACE2 recepto

47 key role by assisting with transition state stabilization and by reducing the pK(a) of the nucleophi

48 RISP inhibition, RyR2/FKBP12.6 complex stabilization and Ca(2+) release blockade may be potenti

49 ach may be broadly applicable to the kinetic stabilization and characterization of other weak functio

50 ly remain unknown because nonsuitable sample stabilization and chromatographic separation methods con

51 accompanied by both a significant energetic stabilization and decreased nuclease sensitivity as unim

52 ereby accelerating SOC turnover through both stabilization and destabilization mechanisms.

53 minal domain in CLASP2 that promotes both MT stabilization and early infection.

54 of competing fate programs precede cell fate stabilization and final commitment.

55 best known for their role in regulating the stabilization and function of actin thin filaments in mu

56 Tiam1 is a key regulator of DG granule cell stabilization and function within hippocampal circuits.

57 ion while Ser62 phosphorylation leads to its stabilization and functional activation.

58 quitin proteasome system responsible for SRF stabilization and KLF4 repression and is required for th

59 ent-forming proteins in bacteria function in stabilization and localization of proteinaceous complexe

60 ounter cell stress conditions and thrive for stabilization and maturation.

61 ral penetrating trauma, allowed for surgical stabilization and minimal solicitation of the area to av

62 tations, resulting in Wnt ligand-independent stabilization and nuclear accumulation of betacatenin.

63 host factor that enables HIV-1 to induce MT stabilization and promote early infection in natural tar

64 ther, these findings suggest that the unique stabilization and regulation of the p53 protein may cont

65 e cell autonomous mechanisms that facilitate stabilization and repair of damaged sarcolemmal membrane

66 ings reveal mechanisms of chaperone-mediated stabilization and secretion of two distinct families of

67 ting mechanisms of soil organic carbon (SOC) stabilization and SOC response to climate change.

68 a prerequisite for phase locking, frequency stabilization and stability transfer among optical carri

69 patients with SSc-ILD have better chances of stabilization and survival, a relentlessly progressive c

70 ypoxia and provides new findings on HIFalpha stabilization and the FN matrix in the context of renal

71 components and SERCA2b, resulting in SERCA2b stabilization and thermogenesis.

72 suggested that the combination of Pickering stabilization and thymol addition to the oil phase can b

73 clusters particularly contribute to cohesin stabilization and transcriptional regulation.

74 of Wnt signaling entails betacatenin protein stabilization and translocation to the nucleus to regula

75 determine if oral NAC can provide long-term stabilization and/or improvement in visual function in p

76 and proximity of substrate, transition-state stabilization, and active-site incorporation will be dis

77 is a crucial chaperone in maintaining mutp53 stabilization, and by using an in silico approach, we bu

78 molecular events involved in CCP initiation, stabilization, and curvature generation.

79 water filtration, nutrient cycling, habitat stabilization, and food web enhancement, but causes have

80 ng the identified METTL3-mediated FOXO3 mRNA stabilization, and overexpression of FOXO3 restores m(6)

81 engineering, affinity purification, chemical stabilization, and quantitative mass spectrometry to inv

82 ed a reduced annual relapse rate, disability stabilization, and reduced brain atrophy after 3 years o

83 G4 formation (folding), stabilization, and unfolding must be regulated to coordi

84 ther it results from plasticity increases or stabilization, and whether facilitation results from lea

85 During movement, however, periods of stabilization are interspersed with non-compensatory sac

86 en assumed that alternative mechanisms of OM stabilization are present(5).

87 wound healing and suggest topical mast cell stabilization as a potentially successful treatment for

88 drogen bonds provides significant structural stabilization as demonstrated by comparison to control s

89 res cortical MT plus ends to enable filament stabilization, as a host factor that enables HIV-1 to in

90 iomaterials exploiting the CH-pai bond-based stabilization, as exemplified by an enzyme-resistant hyd

91 Thermodynamic stabilization at high concentrations and kinetic barrier

92 for the reaction with large transition state stabilization at relatively low OEEFs.

93 ether vestibular pathways contribute to head stabilization at such high frequencies.

94 s work provides an unusual example of mutual stabilization between metal clusters and a self-assemble

95 sigma-interactions, augmented by dispersive stabilization between the alkane ligand and the anion mi

96 op strategies for mine remediation and waste stabilization by accelerating the biogeochemical cycling

97 tudy was to evaluate the effect of Pickering stabilization by biopolymer-based particles (bioparticle

98 at energy dissipation and freshwater content stabilization by eddies increased in the late-2000s.

99 t the relationship between o-quinone methide stabilization by electronic effects provided by the subs

100 anic matter suggests either redox control or stabilization by formation of organometallic complexes f

101 irect microbial pathogens killing and matrix stabilization can occur simultaneously.

102 fur-aromatic interactions provide additional stabilization compared to purely hydrophobic interaction

103 ith WT apoA-I and comparable PON1 activation/stabilization compared with reconstituted HDL (WT apoA-I

104 Most interestingly, the degree of stabilization correlates with the hydrophilicity of the

105 mation and found that the degree of tetramer stabilization depends on the site of the covalent tether

106 important in microbiota studies and that the stabilization device may be useful in maintaining microb

107 Here, we evaluated the ability of a stabilization device to preserve canine fecal samples un

108 Improvements in encephalopathy and medical stabilization did not rapidly normalize rhythms.

109 tionalize scenarios where predicted anomeric stabilization does not occur.

110 uences, we mapped a short ~80-amino-acid UTX stabilization domain (USD) that promotes UTX stability i

111 hibitors by comparing hydrated excess proton stabilization during proton transport in M2 with the int

112 tail recognition, which likely leads to mRNA stabilization during the editing process and impedes spo

113 d to have permitted both lordosis and pelvic stabilization during upright walking are not present in

114 molecule corrector Lumacaftor exerts a helix stabilization effect not only on the E217G mutant hairpi

115 This stabilization effect was specific to ATP6V0C, as overexp

116 ty functional theory calculations, revealing stabilization effects of intermolecular hydrogen bonding

117 30 to 37 degrees C enhances the hydrophobic stabilization effects of retinol.

118 al) delocalization and (energetic) resonance stabilization embedded in VB theory provides a natural a

119 cer frequently occurs as a result of protein stabilization, emphasizing the importance of identificat

120 s accompanied by a large increase in the pai-stabilization energy upon adduct formation.

121 After 35 days of MPB growth and stabilization, four M. liliana were added to each chambe

122 The energetic stabilization, however, is not strong enough to overcome

123 afficking of incoming viral cores through MT stabilization.IMPORTANCE While microtubules (MTs) have l

124 ived LA models to explore the dynamics of RD stabilization in fibrotic regions and generate maps of R

125 rate that APAP treatment leads to HIF-2alpha stabilization in hepatic MPhis and that HIF-2alpha subse

126 translation and ubiquitin-dependent protein stabilization in melanoma.

127 At the molecular level, HIFalpha stabilization in oligodendroglia does not perturb Wnt si

128 of microbial necromass N, its turnover, and stabilization in soil remain poorly understood.

129 An additional Rh-H...C stabilization in some intermediates or transition states

130 and depend on TbSAS-6 and TbBLD10 for their stabilization in the basal body.

131 Without this LNP-mediated stabilization, in Arabidopsis lnp1-1 lnp2-1 mutant cells

132 The extent of stabilization increased with number of Nm modifications

133 icted clinical worsening after 1 year (Fabry stabilization index >20%, P=0.034).

134 and NMR, providing insight into why tetramer stabilization inhibits amyloid assembly.

135 The mechanisms proposed to explain the stabilization involve either mesoscale eddy activity tha

136 lecular dynamics simulation suggest that the stabilization is induced by the coupling between enhance

137 The mechanism of Rad53-dependent fork stabilization is not known.

138 contributes to stabilization of 8N, but this stabilization is not revealed by kinetic studies.

139 ive concentration leads to enhanced packing, stabilization (jamming) and point sintering with phase c

140 romotes DG granule cell dendrite and synapse stabilization late in development.

141 for TA likely affect protein folding and/or stabilization, leading to decreased WNT signaling and co

142 ctions between OM and soil minerals and this stabilization may be of increasing importance in permafr

143 a can nucleate directly through an acid-base stabilization mechanism to form ammonium nitrate particl

144 We present a stabilization method involving the synthesis of DNA bric

145 e model MIMICS (The MIcrobial-MIneral Carbon Stabilization model), which we compared to the widely us

146 calculations attribute this to a significant stabilization of 5 via Ru -> Zn donation.

147 tationally, the t-butyl group contributes to stabilization of 8N, but this stabilization is not revea

148 odification has been ascribed principally to stabilization of a fluoride leaving group (LG) in covale

149 In this study, we report the epitaxial stabilization of a new interfacial phase formed during p

150 essing required for LTM, which relies on the stabilization of a newly synthesized mRNA by a class of

151 The results suggest stabilization of a particularly interesting ground state

152 motes elevation of PI3,5P2, in part, through stabilization of a protein complex that includes its opp

153 In this well-selected system, production and stabilization of a radical species were simultaneously f

154 Herein, we report the stabilization of a remarkably short beta-sheet by incorp

155 ries in zero field is a prerequisite for the stabilization of a skyrmion phase, and discuss how the a

156 by vessel loss and formation, and selective stabilization of a subset of new vessels.

157 Stabilization of a transiently expressed immediate early

158 tropomyosin is essential for its role in the stabilization of actin-tropomyosin filaments in cells.

159 ect cell-cell interaction on adjacent cells, stabilization of adjacent cell surface receptors on the

160 find that the adhered molecules improve the stabilization of an 'atop-bound' CO intermediate (that i

161 We show that stabilization of an active state is dependent on TALI, i

162 s suggest that the retention of activity and stabilization of an enzyme may be balanced by tuning the

163 his study demonstrates that a PRMT1-mediated stabilization of BCL2 mRNA contributes to therapeutic re

164 this methylation enhanced HSP70 binding and stabilization of BCL2 mRNA through AU-rich elements in 3

165 es for the maturation of neural circuits and stabilization of behavior.

166 Disruption of APC results in pathologic stabilization of beta-catenin and oncogenesis.

167 sitivity to GSK3 inhibition is likely due to stabilization of beta-catenin in cohesin-mutant cells, a

168 for proper hindgut morphogenesis, as ectopic stabilization of beta-catenin in the ventral hindgut via

169 rug development that go beyond the metabolic stabilization of bioactive peptides.

170 et-like behavior induced by the trapping and stabilization of charges around defects in the material.

171 The stabilization of cyanidin-3-glucoside (CYG) through bind

172 3 uses a unique two-pronged mechanism in its stabilization of Cyclin D1 to drive cell-cycle and cance

173 mediated by the counterions that promote the stabilization of cylindrical instead of spherical micell

174 The stabilization of dendrites and spines during neuronal ma

175 The growth and stabilization of dendritic spines is thought to be essen

176 iam1, we demonstrate that Tiam1 promotes the stabilization of DG granule cell dendritic arbors, spine

177 Crucial for stabilization of EGFR asymmetric dimer is a "latch" form

178 These insights about the stabilization of energy-storing charge-separated states

179 These results demonstrated that stabilization of Env trimer conformation with BMS-529 im

180 irects the RZZ complex to minimize premature stabilization of erroneous attachments, whereas a decrea

181 We propose that Pop-mediated stabilization of Est1 binding to TLC1 is a pre-requisite

182 electrochemically induced precipitation and stabilization of fresh urine was successfully demonstrat

183 th Arg517 and Asn513 providing electrostatic stabilization of G-T*.

184 In cancer cells, stabilization of G4 DNAs leads to replication stress and

185 ifunctional hybrid nanomaterials through the stabilization of gold nanoparticles with thiol-functiona

186 In one previous approach, stabilization of grain boundaries through relaxation and

187 provide insights into the immobilization and stabilization of halide perovskite semiconductors and de

188 was no further progression of her LSCD, and stabilization of her ocular surface was achieved.

189 90alpha (HSP90alpha) expression, leading to stabilization of HIF1alpha.

190 f F-actin bundles required for the sustained stabilization of highly contractile actomyosin structure

191 le Env conformation is stabilized.Importance Stabilization of HIV-1 Env State 2A has been shown to se

192 re recommendations about the recognition and stabilization of hospital patients at risk for developin

193 CNF1-mediated RhoC activation modulated the stabilization of hypoxia-inducible factor 1alpha (HIF1al

194 Prolyl hydroxylase inhibitors (PHI) promote stabilization of hypoxia-inducible factor-1 alpha and af

195 o promote poly(A) tail (PAT) lengthening and stabilization of individual mRNAs presumably by protecti

196 es osmolytes and hypertonicity, resulting in stabilization of its ID regions.

197 lf5-regulated ubiquitin ligase FBXW7 ensures stabilization of its putative protein substrate IFN-gamm

198 ld be a promising intervention for the acute stabilization of late-stage plaques.

199 Here, we showed that the stabilization of lipase upon MPCI to polymer brush surfa

200 review focuses on the recent progress on the stabilization of LMA with nonaqueous electrolytes and re

201 ence of p53 was mediated by accumulation and stabilization of mature SREBP2.

202 d as a novel mechanism in the maintenance of stabilization of meiotic STAG3 cohesin complex and the m

203 ectively resulting in increased survival and stabilization of metabolic indices.

204 Dramatic effects are observed, including a stabilization of metastable polymorphs, a depression of

205 the favourable synthetic conditions for the stabilization of metastable TMD crystals and at stimulat

206 ule bundle formation and participates in the stabilization of microtubules.

207 en recognized for its unique function in the stabilization of mRNA, which is associated with inflamma

208 P2), a key regulator of cortical capture and stabilization of MTs, interacts with incoming HIV-1 part

209 eveals that ERK inhibition promotes enhanced stabilization of NANOG protein after mitosis.

210 evices, and it may also be leveraged for the stabilization of novel phases and functionalities not ac

211 educed propensity toward aggregation and the stabilization of oligomeric intermediates did not always

212 nteresting option for physical and oxidative stabilization of omega-3 emulsions, while SPH could be u

213 gression and identified one that affects the stabilization of p53.

214 2) apoA-I displayed increased activation and stabilization of paraoxonase 1 (PON1) activity (mumol/mi

215 Stabilization of PGE(2) level by 15-hydroxyprostaglandin

216 which describes the formation, dynamics and stabilization of place fields.

217 mine the properties required for binding and stabilization of poliovirus.

218 aining, and the decrease was associated with stabilization of pre-sleep learning.

219 he accumulation of adenosine but also on the stabilization of pro-inflammatory extracellular ATP to r

220 Stabilization of protein-protein interactions (PPIs) hol

221 These include covalent FBDD, FBDD for the stabilization of proteins or protein-protein interaction

222 curring post-translational modifications for stabilization of purified GPCR in detergent micelles.

223 identifies the relevance of disorder in the stabilization of QSLs.

224 substrate binding cleft as well as selective stabilization of reaction intermediates at the scissile

225 fied nucleotides have been implicated in the stabilization of RNA structure and regulation of ribosom

226 that biased RTK ligands induce differential stabilization of RTK dimers, here, we seek to test this

227 than spliced transcripts, we found a global stabilization of spliced mRNAs upon T cell activation, a

228 a novel role of UBR5 in B-cell maturation by stabilization of spliceosome components during B-cell de

229 ctenyl succinate groups' content resulted in stabilization of starch structure, which was confirmed b

230 the building of artificial cortices for the stabilization of synthetic cells.

231 On brain MRI, within 1 year there was stabilization of T2/FLAIR abnormalities, and after 2 yea

232 l resolution of diffusion MRI abnormalities, stabilization of T2/FLAIR MRI abnormalities, and partial

233 cers, a phenomenon we term cross-interaction stabilization of TFs.

234 a1 signaling through direct binding with and stabilization of TGFBR1 in lung fibroblasts.

235 s in the binding affinity originate from the stabilization of the (E)-boronic acids and the destabili

236 we conclude that the E340A mutation causes a stabilization of the Ca(2+) sites in a more occluded sta

237 d state structures thus show in both cases a stabilization of the cationic silicon center through an

238 f the locked superstructure reveals a 100-mV stabilization of the conduction band energy when compare

239 ral phase transitions, enhanced disorder and stabilization of the cubic phase even for a small amount

240 s and are explicable largely in terms of the stabilization of the developing dipole in the transition

241 VV Vif are required for cofactor binding and stabilization of the E3 ligase complex, such as the zinc

242 P1 bind Ku, promoting Ku multimerization and stabilization of the initial synaptic event for NHEJ.

243 ional theory (DFT) calculations revealed the stabilization of the key intermediate, OCHO*, through in

244 In all cases, the stabilization of the low-spin state is due to the pai-ac

245 suggested to be involved in crosslinking and stabilization of the lubricating superficial layer of ca

246 ed by deubiquitination by USP5, resulting in stabilization of the m(6)A methyltransferase complex.

247 assical hydrogen bonding was involved in the stabilization of the Michael adduct intermediate.

248 efficients are enough to provide for kinetic stabilization of the morphology against demixing at RT.

249 Stabilization of the MT is dependent in part on its acet

250 p of the ligating acetic acid is crucial for stabilization of the palladacyclic intermediate.

251 d] imidazolium} chloride (2) is used for the stabilization of the palladium metal center.

252 revealed a clemastine-induced thermodynamic stabilization of the Plasmodium TRiC delta subunit, sugg

253 Overall, the Dp3sam-C8 ester presents a stabilization of the quinoidal base (blue color) at neut

254 ies of NH...pai interactions involved in the stabilization of the secondary and tertiary protein stru

255 show that genetic depletion or pharmacologic stabilization of the septin cytoskeleton significantly i

256 d rapid evaluation of ligand-induced thermal stabilization of the triple helix, which correlated with

257 Ge(2) Cd triangles plays a vital role in the stabilization of the whole structure.

258 lysine 9 (H3K9) methyltransferase Ehmt1 and stabilization of the zinc finger TF Zic2 at enhancers an

259 Furthermore, we provide evidence for the stabilization of these outer domain interactions through

260 domain of adiponectin, relying on structural stabilization of this domain by bound metal ions.

261 lence the ITCH expression, and result in the stabilization of TP73 protein, which mediated the apopto

262 act of zeolite confinements results from the stabilization of transition state provided by the confin

263 he time before treatment start and after the stabilization of treatment effect following commencement

264 t start; this point represented the point of stabilization of treatment effect, after the maximum tre

265 The posttranslational stabilization of UNC5B by PyST is regulated by the inter

266 Then, stabilization of uncoated/coated nanoliposomes by spray-

267 quired for developmental myelination through stabilization of VHL via K63-linked ubiquitination.

268 Inhibitory stabilization offers a dynamic, fast and flexible compen

269 Modern treatment of ICH focuses on rapid stabilization, often requiring urgent treatment of mass

270 SP2 C-terminal mutant is unable to induce MT stabilization or promote early HIV-1 infection.

271 After stabilization, patients with NVUGIB should undergo endos

272 -MS2 and phiX174-in surface waters and waste stabilization ponds by integrating solar irradiance and

273 oxidized C, respectively, indicate different stabilization processes than at organo-organic interface

274 aphylaxis in humans and mice, whereas PGE(2) stabilization protects against anaphylactic reactions.

275 Virion stabilization required binding of long GlcNAc polymers o

276 en demand and supply-side options in climate stabilization scenarios.

277 ggesting that granularity may promote memory stabilization.SIGNIFICANCE STATEMENT Studying hippocampa

278 ons is crucial to control POM self-assembly, stabilization, solubility, and function.

279 meres, accrued DNA damage, and exhibited p53 stabilization, successfully restored hepatocyte formatio

280 LAIR MRI abnormalities, and partial clinical stabilization, supportive of treatment response.

281 Importantly, microtubule stabilization suppressed multipolarity by improving both

282 Unlike mechanisms of RNA stabilization that depend on direct competition for bind

283 opose a model of Gram-negative cell envelope stabilization that includes cell cycle control and an ex

284 cted molecular adaptation for supercomplexes stabilization that relies on the presence of COX1 indepe

285 lycosylation, perhaps through conformational stabilization that restricts access to N-linked glycosyl

286 aturating inhibitor varies linearly with cap stabilization - the correlation is linear because the ra

287 This work demonstrates the value of enzyme stabilization through computational library design.

288 he electronic structure uncovered electronic stabilization through the opening of a shell-closing gap

289 and plasmids with roles ranging from plasmid stabilization to biofilm formation and persistence.

290 APP at the cell surface promotes ferroportin stabilization to decrease intraneuronal iron.

291 terization by CryoEM reveals a lipid-induced stabilization to the channel, resulting in a 3D reconstr

292 hown that Cx46/50 in turn imparts long-range stabilization to the dynamic local lipid environment tha

293 The electronic stabilization together with the inner core geometric sta

294 lso observed that age-dependent loss of HIF1 stabilization under hypoxia is a phenomenon conserved ac

295 However, HIFalpha stabilization using hypoxia mimetics, does not recapitul

296 ranularity during windows of putative memory stabilization was associated with long-term memory speci

297 For video stabilization, we adopt a novel brightness-invariant opt

298 fungal necromass N production, turnover, and stabilization, we incubated (15) N-labeled bacterial and

299 ubset of patients (n = 88) who achieved mood stabilization with lithium monotherapy, we explored the

300 Therefore, Em stabilization with TREK-1 activators may represent a nov

301 gression and propose that ANG replacement or stabilization would benefit pre-symptomatic ANG-ALS pati