ライフサイエンスコーパス: stage

1 tion during the mid-third instar larval (L3) stage.

2 ms using an in situ thermomechanical testing stage.

3 tion, hepatocellular ballooning and fibrosis stage.

4 lications for the duration of the Hettangian Stage.

5 er therapeutic options for each BCLC-defined stage.

6 more patients were diagnosed at early cancer stage.

7 the disease is usually measured by the tumor stage.

8 , a potentially important developmental life stage.

9 f tau pathology, as assessed by Braak tangle stage.

10 panneuronal expression in the fourth larval stage.

11 hicken BST-2 blocks the virus at the release stage.

12 identified enhancers for each developmental stage.

13 ected regardless of body size or ontogenetic stage.

14 mmunity and environment across various bloom stages.

15 the population characteristics of the other stages.

16 al different tissues and organs at different stages.

17 script during plant growth and developmental stages.

18 ous complex diseases and their developmental stages.

19 tissues from embryonic, fetal, and postnatal stages.

20 from the previously defined T1- and T2-ProSG stages.

21 esia is difficult to detect during its early stages.

22 cal appearance of gliomas or appear at later stages.

23 tend to be affected early during premanifest stages.

24 ility to sense drought at both developmental stages.

25 cohort included patients classified in BCLC stage 0 (9.4%), A (59.5%), B (16.2%), and C (14.9%).

26 cupancy dating to ca. 400 ka (Marine Isotope Stage 11), is one of the very few Middle Pleistocene loc

27 6 in the dorsal pancreatic bud of a Carnegie stage 14 human embryo.

28 hat Notch activation in human tonsil-derived stage 3 (CD34(-)CD117(+)CD94(-)NKp80(-)) and 4A (CD34(-)

29 nd severe, >=30.0) and defined incident CKD (stage 3 or higher) as eGFR<60 ml/min per 1.73 m(2) and >

30 and lowest rate of chronic kidney disease (>=stage 3) from year 1 onwards until study end.

31 lute fibroglandular volume (AFGV)) at Tanner stage 4 (Tanner B4)).

32 disciplinary model of care for patients with stage 5 CKD who want to avoid dialysis, is guided by pat

33 f whom 129 patients were scanned for primary staging, 67 for biochemical recurrence, and 23 for metas

34 ive, collective migration that occurs during Stage 9 of oogenesis.

35 on of cancer has emerged, implicating at all stages a complex and dynamic interaction between tumour

36 apical retinal cell patterning at an earlier stage, accumulate within Sac1(ts) retinal cells due to i

37 rctic glaciation occurred in two consecutive stages across the Eocene-Oligocene transition (EOT): the

38 developed to ensure optimum execution of the stages across two invocations of the pipeline.

39 Any-stage acute kidney injury occurred in 48 of 116 patients

40 cus of this review-is a mid-level processing stage along the ventral visual pathway of the macaque mo

41 leep disorders vary according to the disease stage along with other neuropsychiatric symptoms.

42 proves to be unfeasible, and the "treatment stage alternative" approach, which proposes further ther

43 diversity that is dependent on developmental stage, anatomical region and whether associated with VGL

44 er technology was performed in 110 localized-stage and 556 advanced-stage FL patients.

45 enables detection of lung cancer at an early stage and can reduce the risk of dying from lung cancer.

46 nse, we discuss in broad terms developmental stage and context-dependent functions of lineage-definin

47 mogenous group in terms of age, life history stage and social norms(3,4).

48 rebellar Purkinje cells occurs at an earlier stage and to a greater extent in NPC; therefore, we anal

49 During many stages and conditions in C. elegans, sleep requires a sl

50 ociated astrocytes appeared at early disease stages and increased in abundance with disease progressi

51 tence of refuge areas during intense glacial stages and raise questions concerning understudied migra

52 xible behavior differed across developmental stages and reduced flexible behavior in ASD was driven b

53 nglion cells (RGCs) at various developmental stages and RGCs differentiated in vitro from embryonic r

54 ome-wide losses of variation among the three stages and supports a clear distinction between wild and

55 ion resulted in albinism throughout all life stages and throughout all cells and tissues of this anim

56 We aimed to evaluate prevalence, staging and clinical features correlated with NAFLD amon

57 improvements in diagnostic accuracy for the staging and response assessment of skeletal metastases o

58 F2) restricts influenza virus at the nuclear stage (and perhaps other stages) of the viral life cycle

59 1) associated with lower c (y)pT and c (y)pN stages, and LI, VI, PN, and PD (poor vs other).

60 ring in both initial and progressive disease stages, and preventing truncation may be an effective pr

61 on differences clustering into four temporal stages, and resulting in a gradual increase in membrane

62 not common except in highly susceptible life-stages, and that single infections are the most common s

63 aluated post-LT outcomes, predictors of down-staging, and the impact of LRT in patients with beyond-M

64 findings suggest a paradigm for classifying, staging, and treating these diseases.

65 We staged anthers at every 0.2 mm of development for one wh

66 ate phase in healthy hosts to a lethal lytic stage as host cells become physiologically stressed.

67 rican Joint Committee on Cancer (AJCC) tumor stage at each criterion level was assessed by using Cohe

68 ts) are significantly narrower than of a two-stage baseline method that first estimates the variance

69 detecting diseases of the retina at earlier stages before irreversible structural damage has occurre

70 treatments at different physiological growth stages (before flowering, beginning of flowering, pod-se

71 al for, and the result of, A. fumigatus late-stage biofilm architecture.

72 Therefore, it is essential to identify early-stage biomarkers in those at risk for AD and age-related

73 However, patients with earlier Braak stages (Braak I-IV) did not show elevated tracer uptake

74 Furthermore, patients with early-stage breast cancer who experienced cardiovascular event

75 Fibrosis was staged by a central pathology committee using the Ishak

76 riggers apoptosis during later developmental stages by up-regulating the pro-apoptotic genes reaper a

77 imary analysis) and ARNI therapy initiation (stage C; matched reference).

78 isions about when to use imaging, and inform stage categorization and disease phenotyping among hospi

79 The biofilm lifecycle occurs in three stages: cell attachment, biofilm maturation, and biofilm

80 e 8th edition staging criteria resulted in a stage change for >35% of patients diagnosed with invasiv

81 ved, 473; EAR, 18.2) for advanced- and early-stage cHL, respectively, compared with the general US po

82 Mid stage, congenital defects and neurological lesions in fo

83 ctors of 5-year OS in patients with advanced-stage CRC.Keywords: Abdomen/GI, CT, Comparative Studies,

84 Applying the 8th edition staging criteria resulted in a stage change for >35% of

85 dy of 1386 men with favorable-risk (clinical stage cT1 to cT2bN0M0, prostate-specific antigen [PSA] <

86 and 619 men with unfavorable-risk (clinical stage cT2cN0M0, PSA of 20-50 ng/mL, or Grade Group 3-5)

87 left ventricular assist device implantation (stage D; primary analysis) and ARNI therapy initiation (

88 These sexually committed stages develop from the asexual stages, yet the factors

89 s Plasmodium falciparum sporogonic and blood stage development and impairs Plasmodium berghei develop

90 Men with early-stage disease should not be treated with bone-modifying

91 reated malignancy do not account for current staging, disease biology, or advances in cancer treatmen

92 ion of differential stage susceptibility and stage distribution using a stage-structured Lefkovitch m

93 .1's unique two open states, we report a two-stage E-M coupling mechanism in voltage-dependent gating

94 emical proteomic strategy to track the early-stage entry of ZIKV into host cells.

95 egy for women with newly diagnosed, advanced-stage epithelial ovarian cancer.

96 g the reference standard for prostate cancer staging, especially in advanced disease.

97 embryonic stages through postnatal and adult stages exclusively in a skeletal stem cell population.

98 dvanced NASH (NASH Clinical Research Network stage F3 or F4) were enrolled in 4 multinational clinica

99 s on immune system development in early life stage fishes.

100 rmed in 110 localized-stage and 556 advanced-stage FL patients.

101 ount of all D. melanogaster CS helps set the stage for experimental investigations into their respons

102 These results set the stage for genomics-based approaches in conservation stra

103 euroscience by major discoveries and set the stage for the next 50 years.

104 ile incubation system complete with a mobile stage for XY movement, peristaltic pumps equipped with p

105 Staging for breast cancer now includes anatomic and biol

106 urinary tract (UTUCs) are rare, with poorer stage-for-stage prognosis than urothelial carcinomas of

107 n alternative perspective of normalcy in the stage from abnormal to normal.

108 ho underwent endobronchial ultrasound-guided staging from a single center were included.

109 hylation method that is compatible with late-stage functionalization of drug scaffolds and natural pr

110 Examples are demonstrated of the late-stage functionalization of natural products and drug mol

111 hod can be used for the preparation and late-stage functionalization of pharmaceuticals, as highlight

112 of substrates, including synthesis and late-stage functionalization of scaffolds relevant to medicin

113 triction in reducing BP in patients with CKD stage G3 or G4 and hypertension, we conducted a 6-week,

114 While tumor diagnosis and pathologic staging (gross and microscopic examination of the primar

115 n attempt to increase the plasticity of the "stage hierarchy" approach as well as its adaptability to

116 levels of DDX21 protein were found in 28% of stage I, 21% of stage II, 30% of stage III, and 32% of s

117 eration of Gynaecology and Obstetrics (FIGO) stage IA1 with lymphovascular space invasion, IA2, or IB

118 e one that is associated with the subsequent stage) if the approach linked with the current stage pro

119 ect improvement in outcomes of patients with stage II to IV DAWT compared with historical controls tr

120 protein were found in 28% of stage I, 21% of stage II, 30% of stage III, and 32% of stage IV colorect

121 Stage III is controlled by polymer degradation and invol

122 n patients with resected, BRAF(V600)-mutant, stage III melanoma in the phase 3 COMBI-AD trial.

123 g the highest reported in the literature for stage III NSCLC.

124 d in 28% of stage I, 21% of stage II, 30% of stage III, and 32% of stage IV colorectal cancer cases.

125 t upper lobectomy for remote left upper lobe stage IIIA adenocarcinoma and prior bilateral breast imp

126 d 146 patients with histologically confirmed stage IIIB-IV NSCLC who were treated with immune checkpo

127 Given a single-cell image from one of the stages, ImageAEOT generates an artificial lineage of thi

128 IVF embryos were cultured to the blastocyst stage in vitro or transferred to diabetic and non-diabet

129 ed ion acceleration and creates two distinct stages in the acceleration process associated with the t

130 importance of microbial dormancy and resting stages in the formation of a "buffer" against elevated t

131 stly up-regulated at early post-implantation stages in the primary decidual zone (PDZ) surrounding th

132 ,003) on PET/MRI, leading to a change in TNM staging in 0.5% (5/1,003).

133 Ga-FAPI PET/CT results led to changes in TNM staging in 10 of 19 patients.

134 ificantly increased at the time of metabolic staging in mothers of children with presymptomatic type

135 the NC morphologies at different overgrowth stages indicate that the branching patterns are directed

136 We performed a two-stage individual participant data (IPD) analysis compari

137 ty than ivermectin against hepatic and blood stage infections, respectively.

138 ory and examination, laboratory, and disease staging information were shown using descriptive statist

139 metallaphotoredox-catalysed method for late-stage installation of both tritium and carbon-11 into th

140 sum of boxes score from the CDR(R) Dementia Staging Instrument and in five cognitive domains (episod

141 TAVR, even with baseline impaired eGFR, CKD stage is more likely to stay the same or improve than wo

142 Decreased OC/P RS was found in stage IV Appalachian white males within a subset of stat

143 1% of stage II, 30% of stage III, and 32% of stage IV colorectal cancer cases.

144 iologic factors, although the guidelines for stage IV disease do not account for how these factors ma

145 We retrospectively included 79 patients with stage IV lung carcinomas (n=24), renal carcinomas (n=11)

146 s distributed in 82 normal corneas, 40 early-stage keratoconus and 83 established keratoconus.

147 End-stage kidney disease patients presented frequently sever

148 ndent risk factor for the progression to end-stage kidney failure, cardiovascular morbidity, and prem

149 We diagnose early-stage LA with sensitivity~70-90% and specificity~90-93%

150 of serum metabolic patterns to detect early-stage LA.

151 Among HIV-infected, model of end-stage liver disease (aHR, 1.04; P < 0.001), body mass in

152 End-stage liver disease (ESLD) is a major burden on public h

153 Patients with end-stage liver disease (ESLD) suffer from a high symptom bu

154 rsimonious model consisting of Model for End-Stage Liver Disease (MELD) and LA at admission may predi

155 sick." Our primary outcome was Model for End-Stage Liver Disease (MELD) score at waitlist removal for

156 is of covariance, adjusted for model for end-stage liver disease at time of hospital admission, serum

157 giopathy that progresses to fibrosis and end-stage liver disease by 2 years of age.

158 derived lung epithelial cells to model early-stage lung adenocarcinoma.

159 that, although levels are very low in early-stage lung cancers, ctDNA is present prior to treatment

160 within the whole system (beyond the droplet stage), macroscopic interconnected aggregate clusters fo

161 For cases negative following the first Mohs stage, margin assessments correlated with histopathology

162 niques to purify and profile differentiation stage-matched late erythroblast F cells and non-F cells

163 Microbial resting stages might heavily contribute to microbial biomass and

164 hese elements are as follows: the "treatment stage migration" strategy, which allows moving to anothe

165 asound is an increasingly used complementary staging modality which also allows for diagnostic confir

166 bution of LRS for species described by age + stage models; our analysis starts with estimated vital r

167 The late-stage modification of pharmaceuticals by this method was

168 a longer wavelength, resulted in the second-stage morphology exhibiting termination of lamellae form

169 edly, when overexpressing MMP14 in the early-stage obese adipose tissue, the transgenic mice showed a

170 ected speech in 52 speakers during the acute stage of a left hemisphere stroke.

171 undergo degeneration at the pre-symptomatic stage of Alzheimer's disease (AD).

172 alysis were the etiology of hepatitis B, the stage of Barcelona Clinic Liver Cancer (BCLC) B and C, a

173 ce of excitation and inhibition at the first stage of cerebellar processing.

174 os of excitation and inhibition at the first stage of cerebellar processing.SIGNIFICANCE STATEMENT Th

175 neurons in the brainstem comprise the final stage of descending control of the mammalian peripheral

176 xpression was positively associated with the stage of fibrosis and HCC.

177 in NK cell progenitors, there is an implied stage of human NK cell development in which DNA demethyl

178 at phosphate binding emerged at the earliest stage of protein evolution.

179 re able to regulate osteoclasts at the early stage of rapid palatal expansion and further facilitate

180 d 2017, we analyzed associations between the stage of syphilis (primary vs secondary) and behavioral

181 erapy, supporting the role of NETs in a late stage of TB pathogenesis.

182 f laminin-111 protein therapy at an advanced stage of the disease can have beneficial outcomes.

183 lthy red blood cells (RBCs) during the blood stage of the disease.

184 persion of CINs depends on the developmental stage of the host brain and is limited by the migration

185 The Piacenzian stage of the Pliocene (2.6 to 3.6 Ma) is the most recent

186 f nitrate drives shifts in the dominant life-stage of the population.

187 ut the subcellular localization of the final stage of TPP biosynthesis and the chemical nature of the

188 we define the cell behaviors underlying each stage of vascular remodeling and identify a pathway requ

189 ed ~500 million years ago, during a critical stage of vertebrate evolution when image-forming eyes fi

190 unction across the preclinical and prodromal stages of AD.

191 e of cognitive ability observed in the early stages of Alzheimer's disease (AD).

192 s can have important influences on different stages of biological control programs, including natural

193 known for their role in fission at the late stages of CME, many studies have suggested that dynamin

194 lso plays a regulatory role during the early stages of CME; however, detailed studies regarding isofo

195 regions of the brain, but may affect earlier stages of cognitive processing.

196 step for research on the early life-history stages of corals.

197 During the early stages of cytokinesis, FtsZ protofilaments form a ring-l

198 ic lineage complicates teasing apart at what stages of differentiation autophagy plays a critical rol

199 al regions of South India, each at differing stages of epidemiological transition.

200 -host interaction occurring during the early stages of HIV infection.

201 eral blood CD4(+) T cells of patients at all stages of HIV-1 infection.

202 Identifying early stages of hypersensitivity pneumonitis (HP) is hampered

203 les soon after virus entry and promote early stages of infection.

204 ce of pyrimidine salvage during the earliest stages of infection.

205 gh preventative monitoring programs at early stages of invasion far outweigh the long-term costs asso

206 in NAFLD with advanced compared with earlier stages of liver fibrosis.

207 repulsive molecular brushes during the early stages of mitosis(8), but during mitotic exit the brushe

208 tack may dominate the process during the end stages of mortality in these conifers.

209 Lymphoblast score correlates with the early stages of muscle inflammation identified by histological

210 Different stages of myogenesis are orchestrated and regulated by m

211 nd with high expression during the parasitic stages of nematode development.

212 f lipid rafts by Nef may contribute to early stages of neurodegeneration and pathogenesis in HAND.

213 CDC42 splice variants in regulating distinct stages of neurogenesis.

214 rocessing also plays a central role in later stages of perception.

215 Here, we present a method for separating all stages of Plasmodium-infected erythrocytes through lysis

216 the fMRI response magnitude between adjacent stages of processing in autism: responses are attenuated

217 cle morphology and number density at various stages of processing-above and beyond the information pr

218 Our study may point to distinct stages of progression of COVID-19 lung disease and highl

219 factors repress the Ealpha enhancer at early stages of T cell differentiation, while their decommissi

220 the matrix protein periostin during the late stages of tendon repair, suggesting that persistent NF-k

221 l developments that occur during the various stages of textile manufacturing: from fiber extrusion to

222 We demonstrate which stages of the approach can extract meaningful informatio

223 n capacity; chemokines dominate the earliest stages of the CD8(+)T(M) recall response because of expe

224 ns and political complexity during the later stages of the pre-Columbian era.

225 The main stages of the protocol are data preprocessing and normal

226 sfer chain and stop sever outbreaks in early stages of their appearance.

227 Three stages of thermotropic evolution were monitored continuo

228 romotes immune suppression from the earliest stages of tumor inception to subvert adaptive T cell imm

229 activation of STAT3 and ERK during the later stages of tumorigenesis.

230 MAP20 is expressed during the late stages of vascular bundle development and localizes arou

231 ion-competent and -incompetent developmental stages of Xenopus tadpoles.

232 efficacy of (18)F-rhPSMA-7 PET for primary N-staging of patients with prostate cancer (PC) compared w

233 -1 nuclear import and define the biochemical staging of these steps of infection.

234 irus at the nuclear stage (and perhaps other stages) of the viral life cycle, based on several lines

235 our protocol, we have also demonstrated late-stage olefination and alkynylation of 2-pyridone, contai

236 ments applied at various berry developmental stages on canopy, yield, and free and glycoside-bound te

237 respectively, improved liver fibrosis by one stage or more without worsening of steatohepatitis.

238 ses of mortality due to traits, life history stages, or locations.

239 On univariate survival analysis, TNM stage (p < 0.01), mGPS (p < 0.05), NLR (p < 0.01), MUST

240 as the partner drug to discern whether blood-stage parasite exposure impacts protection against homol

241 ast carbon metabolism are required for blood-stage parasite survival and organelle maintenance.

242 Patients with early-stage PD (duration <3 years) who were not taking dopamin

243 , immunostaining, deep confocal imaging, and staged pharmacological inhibition, we define the cell be

244 ) T cells are critical for controlling acute-stage poliomyelitis (gray matter inflammation), chronic

245 is poorly understood, particularly at early stages preceding neurodegeneration.

246 ract (UTUCs) are rare, with poorer stage-for-stage prognosis than urothelial carcinomas of the urinar

247 An analysis of a >=2-stage progression in MiToS stage showed no difference be

248 The initiation of MSCI is required for stage progression, which enables crossover formation, su

249 Nevertheless, the majority of advanced-stage prostate cancer patients, including those with SPI

250 age) if the approach linked with the current stage proves to be unfeasible, and the "treatment stage

251 score, National Comprehensive Cancer Network stage, PSA level, PSA doubling time, PSA velocity, and t

252 ients undergoing peritoneal dialysis for end-stage renal disease but without cirrhosis were included

253 Patient survival with end-stage renal disease is longer after kidney transplantati

254 oclonal antibody tesidolumab (LFG316) in end-stage renal disease patients awaiting kidney transplant.

255 ive Impairment and Imaging Correlates in End Stage Renal Disease, NCT01883349.

256 mated glomerular filtration rate (eGFR), end-stage renal disease, or death from renal causes), the in

257 educed heart failure hospitalization and end-stage renal disease.

258 ion of diabetes and the leading cause of end-stage renal failure.

259 atin and kinetochores at distinct cell-cycle stages, revealing extensive reorganization of kinetochor

260 ere also significantly associated with Braak stage (|rho| > 0.45, P < 0.01) and Thal phase (rho > 0.5

261 participants who were recruited with a multi-stage sampling technique.

262 choice behavior and decision speed in a two-stage sequential reinforcement-learning task.

263 analysis of a >=2-stage progression in MiToS stage showed no difference between treatment arms during

264 iterature regarding cancer therapies, cancer stage specific prognosis, the kinetics of cancer recurre

265 of these iCGIs is tissue- and developmental stage-specific and, for the first time, we demonstrate t

266 Loss of developmental stage-specific constraint in macrometastases triggered b

267 shed light on strategies for cell type- and stage-specific intervention in cardiac diseases.

268 We constructed developmental stage-specific transcriptional regulatory networks by li

269 he ABA signaling pathway during the seedling stage specifically in darkness.

270 human brain occur in the embryonic and fetal stages-stages that are difficult to access and investiga

271 usceptibility and stage distribution using a stage-structured Lefkovitch matrix model.

272 e transformation at premalignant/preinvasive stages, suggesting that circulating messengers, intercep

273 We explore the interaction of differential stage susceptibility and stage distribution using a stag

274 Comparisons were made with the AJCC staging system and external validation was performed in

275 s better discrimination compared to the AJCC staging system, but also identifies patients at high-ris

276 secutive patients with clinical-radiographic stage T1 to T3, N0 to N3, and M0 NSCLC who underwent end

277 on DNA constitutes a previously unidentified stage, termed here as recycling.

278 In the postanalytical stage, testing results should be carefully interpreted u

279 eloping airway remodelling at a much earlier stage than males.

280 tral reconstructions reveals an intermediate stage that had already lost a large number of genes, inc

281 that Hox expression continues from embryonic stages through postnatal and adult stages exclusively in

282 sphorylate different substrates at different stages, thus enforcing a temporally ordered series of ev

283 In patients with early-stage TNBC, neoadjuvant treatment with atezolizumab in c

284 osphamide as neoadjuvant treatment for early-stage TNBC.

285 th/without NAT and clinical and pathological stage to evaluate rates of downstaging.

286 satory proliferation during the implantation stages to confer embryonic viability.

287 t the risk of RA and identify cases in early stages to prevent or alter disease progression via appro

288 ribed for Toxoplasma gondii, with infectious stages traveling in freshwater runoff and being concentr

289 rivatives and polyaromatics, and in the late-stage trifluoromethylthiolation of medicines and agroche

290 e data provide compelling evidence for early stage TRM fate decisions and the existence of committed

291 modification in P. falciparum asexual blood stages using a suite of biochemical methods.

292 odulation and diverse parasite developmental stages using reverse genetics and holds great potential

293 and is the leading malaria pre-erythrocytic-stage vaccine candidate.

294 s with UrC-ADC before (18)F-FDG PET/CT, Mayo staging was I/II in 8, III in 3, and IV in 10.

295 Here, through four major stages, we extend the original Protocol used to generate

296 imally perturbed in Jag1 mutants until later stages, when ductal remodeling fails, and signs of acina

297 ll differentiation into the final maturation stage, which leads to anovulation.

298 ognostic tool for AD, regardless of clinical stage, which would be of great benefit in clinical pract

299 Transfer of cDC2s isolated from late-stage wounds into healthy skin was sufficient to induce

300 ly committed stages develop from the asexual stages, yet the factors behind this transition are not c