ライフサイエンスコーパス: staggered

1 ayer insertion transitions are different but staggered.

2 tribenzylamine-based platforms, which become staggered.

3 Both eclipsed (1a) and staggered (1b) conformations are found in solution; the

4 asimir force phase transitions between these staggered 2D materials induced by the complex interplay

5 In staggered 3-month intervals, ASP teams at 3 hospitals re

6 ure demonstrates that both eclipsed (3a) and staggered (3b) allyl conformation are present.

7 desymmetrized hcb topology and consists of a staggered AB stacking structure with elliptical pores.

8 , resulting in new structures similar to the staggered AB stacking, namely, quasi-AB-stacking structu

9 -438 are weakly correlated along c to form a staggered ABAB stacking that reduces the Coulomb repulsi

10 tive PNA-like conditions, culminating in the staggered abandonment of many major Native American rive

11 We enrolled subjects following single or staggered acetaminophen overdose with normal serum alani

12 asitoid introduction, despite releases being staggered across locations in different years.

13 pseudostratified epithelia, where nuclei are staggered across the tissue, each nucleus migrates apica

14 efined as RV1 and OPV given on the same day; staggered administration as RV1 and OPV given >/=1 day a

15 For staggered administration, we found no evidence that the

16 g and have been extensively characterized as staggered and blunt double-strand breaks.

17 ence-in-differences analysis, exploiting the staggered and selective introduction of voluntary licens

18 probiotic kefir given in combination with a staggered and tapered antibiotic withdrawal regimen may

19 ic data establish that the allyl ligands are staggered and that the trimethylsilyl substituents are i

20 from tetrameric complexes of extended, half-staggered, and antiparallel oriented coiled-coils.

21 its cognate site 5'-ACGCGT-3' as a stacked, staggered, and noncovalent cooperative dimer.

22 A lattice quench is designed to convert the staggered angular momentum, previously thought by expert

23 tronger hyperconjugative interactions in the staggered anti and gauche conformers than the eclipsed s

24 gnetic resonance spectroscopy, to show how a staggered antiparallel coiled-coil 'BASS' (bipolar assem

25 whose shape and volume are consistent with a staggered antiparallel dimer.

26 (f) group bind to the minor groove of DNA as staggered, antiparallel dimers in a sequence-specific ma

27 ve at their cognate DNA sequence as stacked, staggered, antiparallel dimers.

28 The staggered appearance of primary response cytokines direc

29 ion often occurs abruptly, but a slower more staggered approach may also be used.

30 cleotide binding to two subunits, generate a staggered arrangement of ClpX subunits and pore loops ar

31 Our MMM device consists of a staggered arrangement of pillars which enables real-time

32 Crosslinking experiments suggest a staggered arrangement of pore loops in the hexamer and n

33 ide-chains in the primary sequence and the D-staggered arrangement of the triple-helices.

34 he Col108 mini-fibrils are consistent with a staggered arrangement of triple helices having a stagger

35 tions between the triple helices in a 1-unit staggered arrangement.

36 lignment to a stable approximately one-third staggered arrangement.

37 ar fibres comprised of micelle subunits in a staggered arrangement.

38 (or platelets), and (ii) the imbricated, or staggered, arrangement of these lamellea, bound by biopo

39 nts in which the three strands are held in a staggered array by disulfide bonds.

40 t consists of collagen fibrils composed of a staggered array of ultra-long tropocollagen (TC) molecul

41 Staggered arrays of collagen molecules form fibrils, whi

42 structure, the microtubules were arranged in staggered arrays, cross-linked by tau proteins.

43 The magnifications and staggered arrivals of the supernova images probe the cos

44 We measured the impact of staggered ASP implementation on consumption of 18 ASP-ta

45 In addition, to direct staggered assembly of peptides and to foster fibrillogen

46 xtures) from those where odourant onsets are staggered (asynchronous mixtures) down to an onset delay

47 r the lowest-energy triplet excited state of staggered [Au(CN)(2)(-)](2) show the formation of a Au-A

48 plain the diastereoselectivity that involves staggered axial attack on the sp(2) carbon opposite to t

49 and Nb:STO heterojunction, and it exhibited staggered band alignment.

50 istinct semiconductor materials with type II staggered band offset are both in contact with one small

51 y photoemission experiments, that a type-II, staggered, band alignment of ~ 0.4 eV exists between ana

52 ructure shows open protein conformations and staggered base pair conformations, indicating that N7-me

53 omplexes adopt an open protein conformation, staggered base pair, and one active-site metal ion.

54 ilaments, consisting of tightly paired, half-staggered beta strands related by a screw axis, can be f

55 rands, with azobenzene moieties deliberately staggered between the bases that define the complementar

56 wings of Microraptor could have resembled a staggered biplane configuration during flight, where the

57 ning Pro-Hyp-Gly repeating sequences and two staggered bipyridine ligands within the peptide was synt

58 nterlock mechanism that selects the required staggered bond orientation.

59 e, and then catalyse a concerted four-strand staggered break in the DNA substrates whilst forming tra

60 D attacks cytosines on both DNA strands, and staggered breaks are processed to blunt DSBs at the init

61 g is supposed to form circular plasmids with staggered breaks, which can be repaired in Escherichia c

62 Interestingly, CSR induced by staggered but not blunt, double-stranded DNA breaks was

63 o different vectors were infused together or staggered by 1, 3, or 5 weeks, and two-color fluorescent

64 agen molecules, types II and III in register staggered by 4D from another type III molecule.

65 monomer adopt out-of-plane positions and are staggered by about three peptide layers ( approximately

66 ntiparallel coiled coil, with the two chains staggered by only 4 amino acids and displaying hydrophob

67 A crystal lattice comprising uniformly staggered C5H5 rings was found to be lower in energy by

68 chain and the mutation site in a neighboring staggered chain influences the disruption of the standar

69 y in PBDT[2F]T leads to more pronounced, yet staggered, chain stacking, which generally leads to high

70 he 20 bp centred on the midpoint of the 4 bp staggered cleavage made by gyrase to be the 'core' and t

71 calation of the hydrocarbon at either of the staggered cleavage sites or immediately adjacent to the

72 FnCas9 produces staggered cleavage, higher homology-directed repair rate

73 We identified a pair of transient staggered cleavages six base-pairs apart centered around

74 R repertoire is progressively diversified by staggered clonotypic expansion, according to functional

75 nded porous graphitic layers that are either staggered (COF-1, P6(3)/mmc) or eclipsed (COF-5, P6/mmm)

76 In the crystal, 1 forms staggered cofacial dimers (centroid distance of 3.38 A).

77 sites are closely aligned within the quarter-staggered collagen fibril, suggesting a multivalent inte

78 We observe that staggered commutation enables time-reversal symmetry bre

79 sive non-reciprocity based on the concept of staggered commutation.

80 have a high-spin (S = 2) ground state in the staggered configuration (180 degrees rotation angle).

81 TP analogs not pairing with but instead in a staggered configuration relative to 1,N(6)-dA in the ant

82 e six Au(2)(SR)(3) staples are arranged in a staggered configuration, and the Au(38)S(24) framework h

83 nal porous layers that are likely stacked in staggered conformation (hxl topology).

84 emonstrate that the two p53 dimers favored a staggered conformation in which they make favorable inte

85 P-driven proton pumping, indicating that the staggered conformation is compatible with normal enzymat

86 fferent interactions indicates that ethane's staggered conformation is the result of preferential sta

87 rotator at a geometry that destabilizes the staggered conformation of the rotator through van der Wa

88 onverts to the thermodynamically more stable staggered conformation when heated above 85 degrees C.

89 The molecules adopt the staggered conformation with the tertiary fluorine in the

90 s of cyclic alcohols intrinsically prefers a staggered conformation, although the eclipsed conformati

91 ate that [1-(t-Bu)C(9)H(6)](2)Cr exists in a staggered conformation, with Cr-C (av) = 2.32(4) A.

92 t, have no influence on the preference for a staggered conformation.

93 able eclipsed conformation and the preferred staggered conformation.

94 e-chains of residues adopt several specific, staggered conformations, known as rotamers within protei

95 provides the products in their lower energy staggered conformations.

96 on leads to the formation of polymers with a staggered contoured spiral structure.

97 Staggered coupling of the two opposing hexamers position

98 pe hemes arranged in the peculiar shape of a staggered cross that trifurcates the electron flow, pres

99 nd in light of the apparently well-conserved staggered cross-heme wire structural motif in functional

100 However, the orientation of the staggered cross-link can have a significant effect on th

101 ar models suggest that formation of the -GC- staggered cross-link disrupts hydrogen bonding and may a

102 stability of the duplex that contains a -GC- staggered cross-link is 10 degrees C lower than the melt

103 Unlike the -CG- staggered cross-link, in which the cross-linked base pai

104 is seen with the duplex that contains a -CG- staggered cross-link.

105 Mismatched C-C or -CG- staggered cross-linked duplexes that have complementary

106 t just one of the two sites and results in a staggered cut 25-26 nt downstream of the top strand sequ

107 Finally, we discuss how the staggered-cut palindromic target site model can be used

108 lanogaster genome to test predictions of the staggered-cut palindromic target site model for DNA tran

109 tes indicates that DNA transposons recognize staggered-cut palindromic target site motifs (TSMs).

110 We show that IntN1 makes 7 bp staggered cuts on the top and bottom strands.

111 Excision of CTnDOT involves staggered cuts that produce 5 bp chromosomal sequences a

112 Previously we showed that IntN1 makes 7-bp staggered cuts within the NBU1 att sites, and certain mi

113 on occurred with opposing dG/dC but not with staggered dA/dA.

114 A staggered delivery scheme of the two agents (TMRE inject

115 The staggered delivery strategy was evaluated under both nor

116 From the average EH values for staggered dimers and trimers, the excited-state Au-Au an

117 he hydride and a -CH2CH2O(t)Bu ligand with a staggered disposition.

118 hosphate cofactor and the generation of long staggered DNA breaks during transposition.

119 ed and provide evidence supporting a role in staggered DNA double-strand break repair.

120 ds, respectively, and for jointly generating staggered DNA double-strand breaks.

121 Moreover, Cpf1 cleaves DNA via a staggered DNA double-stranded break.

122 it ('/' denotes the cleavage site) producing staggered DNA ends.

123 ed annealing and extension steps to generate staggered DNA fragments and promote crossover events alo

124 n metallic strip with periodic subwavelength staggered double groove arrays supported by a flexible d

125 The break appears to be a staggered double-strand break consistent with an error i

126 (single-strand nicks at Mu ends, joined to a staggered double-strand break in the target), the flanki

127 repeats, suggesting an origin via repair of staggered double-strand breaks.

128 ner than those predicted by the classic half-staggered, double-stranded mechanism, must quickly form.

129 Electrokinetic effects drive the assembly of staggered doublets and triplets of nanorods that are mov

130 es and indicates that most repair events for staggered DSBs, at least in barley, involve the sister c

131 e tetrahydrofuran residues in the (AP)(2)-5'-staggered duplex contrasts with their smooth alignment a

132 e sugar-phosphate backbone in the (AP)(2)-3'-staggered duplex.

133 Waals repulsive interactions and reduces the staggered/eclipsed relative energy difference.

134 A-damaging chemotherapy, we report that time-staggered EGFR inhibition, but not simultaneous coadmini

135 Bottom contact, staggered-electrode indium gallium zinc oxide transistor

136 ges within COF-420 are the main cause of the staggered electronic structure in this square grid of at

137 ible dielectric substrate, leading to unique staggered EM coupling and waveguiding phenomenon.

138 and broad ranges of temperature dependence, staggered-end DNA target cleavage, and a requirement for

139 ersial whether Cas9 generates blunt-ended or staggered-ended breaks with overhangs in the DNA.

140 , suggesting that exoribonucleases generated staggered ends in the absence of specific Mini-III-catal

141 at Cas9-catalyzed DNA cleavage produces 1-bp staggered ends rather than generally assumed blunt ends.

142 '-R on each strand to produce four-base (5') staggered ends.

143 Survival analysis with staggered entry was used to evaluate the effect of HAART

144 2011-2012 was the result of >/=6 temporally staggered events, spanning from 1 reactivation case to a

145 uring the 6.5 years of DCCT; then, both were staggered every fourth year during EDIC with the full co

146 The staggered extension process (StEP) is essentially a modi

147 rounds of evolution using DNA shuffling and staggered extension process (StEP) resulted in modest im

148 R reaction and further diversified through a staggered extension process.

149 that combined antibody chain shuffling and a staggered-extension process to produce unbiased librarie

150 s the result of sampling error or temporally staggered extinctions is unclear.

151 that implemented universal vote-by-mail in a staggered fashion across counties, allowing us to use a

152 metry: Multiple Hox genes are expressed in a staggered fashion along its primary body axis, and the t

153 The program was deployed in a staggered fashion at 19 hospitals between August 1, 2016

154 rge in the United States in a geographically staggered fashion beginning around 2011.

155 g Critical Care implementation occurred in a staggered fashion between October 2011 and November 2012

156 perpendicular to the flow direction and in a staggered fashion in the 450-pL mixing chamber to enhanc

157 and it promotes the molecules to stack in a staggered fashion thereby pairing itself with either a p

158 on strategies implemented prospectively in a staggered fashion.

159 This study was designed as a staggered, fast-track, randomized, antigen and adjuvant

160 mass spectrometry (LC/MS/MS), and eight-way staggered flow injection MS/MS following 384-well plate

161 joining, a substrate containing a model of a staggered free radical-mediated double-strand break, wit

162 e-series microbial RNA-Seq analyses revealed staggered functional responses to diet shifts throughout

163 Scanning tunneling spectroscopy reveals staggered gap (type II) band alignment between adjacent

164 s to form either "straddling-gap" type-I or "staggered-gap" type-II heterojunctions.

165 leghemoglobin is established by a favorable staggered geometry of the proximal histidine.

166 ectrometry (MUX-LC/MS/MS), four-way parallel staggered gradient liquid chromatography tandem mass spe

167 it utilizes a finite-difference method on a staggered grid to solve for the acoustic eigenmodes (fie

168 %-54%) than those who received both vaccines staggered >/=1 day (63%; 57%-70%; P < .001).

169 Here, we report our observations of multiple staggered helical structures of two canonical coiled coi

170 changes in the helical registry that lead to staggered helices have only been proposed for a few spec

171 usual heptad register shift between adjacent staggered helices.

172 f this 'desensitization ring' is mediated by staggered helix contacts between adjacent subunits, whic

173 study we examine the experimental use of the staggered herringbone mixer (SHM) for the signal enhance

174 In this study we examine the use of the staggered herringbone mixer (SHM) to increase the effici

175 annels (called reactor I) and the other with staggered herringbone mixers (called reactor II), were s

176 onfigurations, including the slanted groove, staggered herringbone, and herringbone mixers.

177 e and flanking ion-pairs were used to direct staggered heterodimers.

178 The crystal structure reveals a staggered hula-hoop geometry.

179 dule combining 2 distinct vaccine types in a staggered immunization regimen: one inducing high-titer

180 witch from proliferation to meiotic entry is staggered in late-larval and adult germlines.

181 proposed in which fibrillin-1 molecules are staggered in microfibrils.

182 The ends of the two protofilaments are staggered in relation to each other, suggesting that cap

183 reo-(tBu3SiO)3HTaCHDCHDOEt (2-CHDCHDOEt) are staggered in solution, according to (1)H NMR spectroscop

184 tioned on opposite strands of the duplex and staggered in the 3' (-1 duplex, (AP) 2-1 duplex) or 5' (

185 In the first duplex, the AP residues are staggered in the 3' orientation [-3 duplex, (AP)(2)-3 du

186 le in the second duplex, the AP residues are staggered in the 5' orientation [+3 duplex, (AP)(2)+3 du

187 on the non-complementary strand, leading to staggered instead of blunt DNA breaks.

188 Staggered interruption, whereby nucleos(t)ide reverse tr

189 s of a -CG- or -GC- step are linked to give "staggered" interstrand cross-links were prepared using a

190 options, including varying coverage levels; staggered introductions; and a one-time, large-scale vac

191 We observed that this is achieved through staggered lateral interactions between self-assembly sur

192 The two ring-shaped hexamers are staggered, leading to a kinked axial channel.

193 termini face, and may occur symmetrically or staggered, likely important for the formation of higher-

194 The conjugate forms a staggered linear oligomer that differs substantially fro

195 magnetic monopole crystal is stabilized by a staggered magnetic field in the pyrochlore iridate Ho2Ir

196 es can be reconfined by the application of a staggered magnetic field.

197 poles in a spin ice at equilibrium through a staggered magnetic field.

198 hase, the interaction dominates and produces staggered magnetic ordering.

199 between the external magnetic field and the staggered magnetization enabled by strong spin-orbit int

200 The staggered magnetization of the 5 nm thick CuMnAs layer i

201 of a peak in the spin structure factor and a staggered magnetization that is close to the ground-stat

202 hiopods), and Dfd (in both brachiopods) show staggered mesodermal expression.

203 The ligands bind in a staggered mode with respect to one another creating a si

204 us providing further support for the quarter-staggered model of collagen fibril axial structure.

205 he distances between the C3 centroids of the staggered monomers are at the short end of those normall

206 es to bind in the minor groove of DNA in the staggered motif, and it also increases the binding affin

207 inding of polyamides to DNA in a stacked and staggered motif.

208 These staggered multispecies waves of diel gene transcription

209 Live-imaging shows that the staggered muscle pattern involves attraction to tendon c

210 s spillover excitation generates patterns of staggered neurotransmitter release from different MNTB a

211 mediator of the breakage, processing of the staggered nicks induced by DNA topoisomerase II, includi

212 packaging enzyme of phage lambda, introduces staggered nicks into viral concatemeric DNA to initiate

213 tion mechanism by making a pair of transient staggered nicks invariably at 6-bp spacing as the reacti

214 u polymerase generating a plasmid containing staggered nicks.

215 hains in anatase TiO(2) , thereby shortening staggered octahedron chains to form an amorphous buffer

216 tinct conformations, either eclipsed (1a) or staggered-off (1b).

217 ks and double-strand breaks that were either staggered or blunt.

218 (C-H) bonds determines the preference of the staggered or eclipsed structure as the energy minimum st

219 nteractions that constrain the subunits to a staggered or out-of-phase mode of operation.

220 e of a spectacular ultracold superfluid with staggered orbital currents in optical lattices.

221 dimers are arranged in an anti-parallel and staggered orientation at this site.

222 to ensure that the patchy spheres select the staggered orientation of tetrahedral bonds on nearest-ne

223 In contrast, the staggered orientation of the proximal histidine found in

224 C2 can populate two distinct orientations: a staggered (out-of-register) fibril and an aligned (in-re

225 owed up until death or the end of the study (staggered over 2001-06) by use of direct or proxy interv

226 tial colonization of different haplotypes is staggered over time and when a barrier to colonization i

227 ent of the photosynthetic protein complexes, staggered over two tightly stacked planes.

228 odels and left- and right-handed models with staggered packing in the coiled-coil domains.

229 anded dimeric coiled-coil and whether or not staggered pairing between nonhomologous residues in the

230 e RstR footprints exhibited a characteristic staggered pattern of DNase I-accessible regions that sug

231 Staggered patterns of withdrawal of life-support therapy

232 lanced state via heterozygote advantage (the staggered phase), and (iii) finally, if recombination un

233 pological band structure originates from the staggered phases of sp orbital tunnelling, requiring nei

234 Staggered plantings indicated that interactions likely o

235 broadband coplanar waveguide (CPW) to planar staggered plasmonic waveguide (PSPW) transitions are des

236 des at subwavelength scale enabled by planar staggered plasmonic waveguides (PSPWs).

237 ) pyrimidinone photoadduct in each strand at staggered positions 28 base pairs apart.

238 ctrostatic and hydrogen bond interactions at staggered positions along the linear assembly.

239 ed plasmids in which each strand carried, at staggered positions, a single thymine-thymine pyrimidine

240 etries using molds with rectangular internal staggered posts (mesh, ME), without posts (plain sheet,

241 For peristaltic motor patterns, the staggered premotor temporal pattern determines the phase

242 Regeneration was found to be a staggered process, with only 25% of axons crossing the r

243 erogeneous populations of non-productive and staggered productive intermediates arise at different re

244 the growing season resulted in a gap in the staggered progression of flowering and fruiting in the c

245 tituted vertices of 9 strongly interact in a staggered propellane-like fashion.

246 miner-blind study comparing the effects of a staggered prophylaxis on gingivitis was then conducted,

247 However, this "staggered regeneration" can be temporally compressed by

248 C and Tb'A90C, indicating the existence of a staggered relationship between helices of the two chimer

249 r, the M3 segments from the two subunits are staggered relative to each other in the vertical axis of

250 Individual neurons had transient activation staggered relative to one another in time, forming a seq

251 The formation of collagen fibrils from staggered repeats of individual molecules has become "ac

252 oser than in canonical coiled coils, and are staggered, resulting in a bend.

253 Intriguingly, in this process, the staggered riboflavin dimers do not interact in ground an

254 of rotational substeps, and that stalks form staggered, right-handed coiled coils, are investigated h

255 ization exhibited a spatially and temporally staggered sequence leading to the adult pattern.

256 oreover, C2c1-mediated cleavage results in a staggered seven-nucleotide break of target DNA.

257 It also accommodates staggered sgRNA sequences.

258 nvolve the two FPH-1 molecules in a slightly staggered, side-by-side, and antiparallel arrangement su

259 o an A/T rich sequence of 6 bp in a slightly staggered, side-by-side, and antiparallel arrangement.

260 recently proposed mechanism of inversion via staggered single-strand breaks as well as ectopic recomb

261 the attachment of each element 3' DNA end to staggered sites in the host DNA by element-encoded integ

262 es which were assumed to define the putative staggered sites of cleavage.

263 f a hexagonal lattice, such a state supports staggered spin loop currents in real space.

264 that the single-chain Hamiltonian contains a staggered spin-exchange term.

265 The staggered spin-orbit order spontaneously breaks rotation

266 wo heterocycles at the C-terminal and (ii) a staggered stacking mode in which the N-terminal heterocy

267 nic layers switch from an eclipsed mode to a staggered stacking mode, leading to the discovery of an

268 mamido polyamides bind preferentially in the staggered stacking mode, while the unsubstituted analogu

269 positional isomer of the recently reported "staggered" stannyl-ligated counterpart [Ge18Pd3{Sn(i)Pr3

270 was for 3 months (13 weeks) per center, with staggered start dates to account for seasonal variation.

271 g with MMS for 35 weeks at each center, with staggered start times.

272 The staggered states occur less than 2% of the time and abou

273 a coupled fashion as against the traditional staggered stick-slip motion.

274 sts of charge-ordered Mn(4+) and Mn(3+) with staggered strain-enhanced Jahn-Teller distortions within

275 We found that the preference of the staggered structure over the eclipsed structure of BH(3)

276 Stabilization of the staggered structure through rotation-induced weakening o

277 e favorable, because it will experience only staggered substituents.

278 a positive magnetoresistance that probes the staggered susceptibility of a pseudospin-half square-lat

279 ltered and results in what we have termed a "staggered sweep." It is named for its three-phased traje

280 explains and predicts the annually repeated, staggered, synchronous and bimodal flowering of many tre

281 orm to probe Dirac-like physics in honeycomb staggered systems in such a ubiquitous interaction.

282 ame time organize into laminar patterns with staggered terminations that stack along the septo-tempor

283 s by providing subjects a prophylaxis at two staggered time points.

284 We leveraged the geographically staggered, time-varying rollout of the P4P program to si

285 ates, which are believed to be linked to the staggered titration of key acidic residues.

286 The change from a staggered to a gauche indenyl orientation lowers the sym

287 ed by Ras via a conformational change from a staggered to an eclipsed position of the nonbridging oxy

288 ii) intercalation immediately outside of the staggered Top2 cleavage site, and to a lesser extent in

289 ic positions in a duplex sequence containing staggered Top2 cleavage sites on both strands.

290 orating a Cas9-linked selection marker and a staggered transfection strategy promotes targeting effic

291 ed by subtle energetic differences between a staggered transition state with less torsional strain an

292 hin the bilayer because they assemble into a staggered transmembrane beta-sheet.

293 cyclosporin was 143+/-13 and for RAD 38+/-3.Staggered treatment completely prevented rejection in fo

294 The strategy depends on the formation of a staggered triple helical species facilitated by intercha

295 ental change resulted in a major, temporally staggered turnover event that profoundly reorganized mar

296 an extended conformation most likely with a staggered versus stacked alignment.

297 ive immune responses, respectively, arise in staggered waves of development from distinct progenitors

298 intensity, are illusory when sarcomeres are staggered with respect to one another.

299 es of the two hexagonal layers are partially staggered, with one hexagonal layer rotated by about 16

300 teau with rA8; another proposed a so-called 'staggered zipper' model in which oligo(rA) strands overl