ライフサイエンスコーパス: start from

1 roughput imaging flow cytometry are possible starting from 0.5 and 3.0 mL of urine respectively.

2 l activity and C1-INH antigen concentration, starting from 0.5h after first dose of C1-INH and lastin

3 f transcriptional changes in skin during TE, starting from 1 h to 7 days of expansion.

4 vatives (9-diethylbenzo[a]phenoxazin-5-ones) starting from 1-naphthols or 1,3-naphthalenediols.

5 Starting from ~1 ng of high molecular weight DNA, we pro

6 ed per 250 mug/L decrease in serum ferritin, starting from 1250 mug/L.

7 Development Assistance for Health estimates starting from 1990 and domestic health spending estimate

8 1990 and domestic health spending estimates starting from 1995.

9 be obtained by a nonstereoselective approach starting from 2'-F U.

10 Here we show that the enzymatic synthesis starting from 2,4-diethyl pyridinedicarboxylate leads to

11 sembled via double dehydrogenative coupling, starting from 2-aminobenzyl alcohol/1-phenylethanol and

12 Almost 100 references starting from 2012 are cited.

13 dynamics, and multi-functional applications starting from 2015 will be highlighted to deepen underst

14 use of structurally modified NBEs (smNBEs), starting from 2015, has become an important approach to

15 of pesticides in food samples for the period starting from 2016 to 2020.

16 Starting from 231,492 and 190,437 acceptable conformatio

17 ommend the assessment of specific IgG titers starting from 24 months to decide for further doses.

18 led a short synthesis of the natural product starting from 3,5-dibromo-2-pyrone.

19 Starting from 3-hydroxy piperidines, a novel transition-

20 Starting from 3D-printed and laser-cut components, assem

21 methylated pyridines (3-8) was investigated, starting from 4-chloro-3-fluoropyridine.

22 , (i) a six-step classical heterocyclization starting from 5-chloro-1-methyl-4-nitropyrazole and (ii)

23 nted much more distinctly in neural dynamics starting from ~500 ms after stimulus onset.

24 rface area decreased progressively by 30-40% starting from ~6 months of age.

25 The unique capability of this framework, to start from a GMST timeseries and efficiently calculate t

26 EVD outbreaks typically start from a single case of probable zoonotic transmissi

27 A step-up approach starting from a 1-2 food elimination diet and increasing

28 ent, which predicts spray radii distribution starting from a 100 mum radius, we show that surfactants

29 2-N(CH(3) )(2) -functionalized phosphinines, starting from a 3-N(CH(3) )(2) -substituted 2-pyrone and

30 e explored transcriptomic profiles of livers starting from a 910-obese-patient cohort, which was furt

31 ightforward synthesis of azetidine-3-amines, starting from a bench stable, commercial material is pre

32 gashira-Sonogashira multicomponent reactions starting from a bromo-triflato-functionalized psoralen s

33 The strengths of this approach include starting from a clearly defined causal estimand and expl

34 (S)-epsilon-oxapipecolic acid is described, starting from a commercially available glutamate diester

35 ate that a bromonium-induced ring expansion, starting from a common tetrahydrofuran-containing bicycl

36 Starting from a completely inactive structure, the simul

37 Starting from a comprehensive 12-state model of the equi

38 force values but is critically dependent on starting from a configuration with highly elongated amni

39 operty relationships for energetic molecules starting from a crystal structure can be achieved and sh

40 olycyclic halichondrin C1-C14 building block starting from a d-gulono-1,4-lactone-derived intermediat

41 cently, inverse design methods have emerged, starting from a desired property and optimizing a corres

42 Here, starting from a few first principles, we layout biophysi

43 Starting from a fragment derived lead compound, we have

44 Starting from a fragment-sized scaffold, we generated op

45 Starting from a gene list as input, DTG offers automated

46 Starting from a generalised model, we realise disordered

47 dihydropyrazole (DHP) RIP1 kinase inhibitors starting from a high-throughput screen and the lead-opti

48 Starting from a high-throughput screening (HTS) hit of o

49 ccount for the separation of the two domains starting from a homogeneous array of cells, and thus for

50 Starting from a Kdo(2)GlcNAc(2) tetrasaccharide precurso

51 Starting from a known beta-methyltyrosine derivative (8)

52 omputational and structurally enabled design starting from a known kinase hinge binding motif.

53 Starting from a list of polymorphic Alus, TypeTE identif

54 A head-to-head competition of the two pools starting from a low (5 x 10(12)) sequence diversity reve

55 ment and quantitative modeling, we show that starting from a minimal MinE-MinD interaction motif, pat

56 Starting from a murine HCC model, we identify a miRNA ne

57 Starting from a mutant that remains covalently bound to

58 the frequency of life in the universe, even starting from a neutral or pessimistic stance.

59 Starting from a non-selective screening hit, we have ach

60 ness and diversity increased during the year starting from a pioneering community that is gradually s

61 Starting from a platform Rhodobacter sphaeroides RC bear

62 Starting from a preliminary list of 19 potential items,

63 Here we want to do the opposite: starting from a prescribed function, can we find a circu

64 t running, and curved running were simulated starting from a random initial guess to confirm the capa

65 Starting from a screening hit (3), a program to discover

66 Starting from a set of 2284 genes, stepwise filtering fo

67 Force-extension curves were simulated starting from a set of 66 structures with substantial st

68 es has already been independently generated, starting from a set of single-molecule conformations.

69 Starting from a set of variants in variant call format (

70 Starting from a simple alpha,beta-unsaturated ester, an

71 ation for gene sets on interaction networks, starting from a simple phenomenological model of a livin

72 Starting from a single aptamer, we create an array of ap

73 versified library of N-containing compounds, starting from a single carboxylic acid, based on the sel

74 fucosylated and sialylated oligosaccharides starting from a single chemically synthesized tri-N-acet

75 raries spanning a wide range of compositions starting from a single parent copolymer.

76 Starting from a single precursor, the readily available

77 Starting from a single stem cell type, extended pluripot

78 wo cooperative, three-binding-site receptors starting from a single-site-and thus noncooperative-doxo

79 atch up on lost sleep, even though they were starting from a sleep-deprived baseline, suggesting that

80 Starting from a small selection of topographically desig

81 iPt(3)@NiS heteronanostructures is reported, starting from a subsulfido bridged heterobimetallic nick

82 Starting from a two-chain complex structure, structurall

83 On this basis, starting from a virtual screening campaign and subsequen

84 ard Agg 2 and Agg 3 indicate that nucleation starts from a central kinetically trapped state Agg 1 an

85 Often, one starts from a given circuit, and using simulations, asks

86 We present a novel approach that starts from a neuroscientific investigation of insect se

87 Starting from about 4 postnatal weeks, SOD1-G93A and wil

88 used to install a transient chiral auxiliary starting from achiral precursors, which then directs dia

89 veloped for the synthesis of bisphosphinates starting from acyl chlorides.

90 tein cholesterols, systolic and diastolic BP starting from age 18 years for every participant.

91 ion EM density map-guided structure modeling starting from amino acid sequences.

92 A formal synthesis of artemisinin starting from amorphadiene is described.

93 ated pH gradient in a large-scale experiment starting from an agricultural, topsoil removed state.

94 ent game improvement, Foldit players can now-starting from an extended polypeptide chain-generate a d

95 Starting from an extensive range of ketones, it was poss

96 Starting from an in-house proprietary screening hit foll

97 Starting from an in-house purine-based compound, optimiz

98 athways of the apo adenosine receptor (A2A), starting from an inactive conformation, by applying adap

99 ation process has been elucidated for a GPCR starting from an inactive structure only, using a non-bi

100 but are still able to form bipolar spindles, starting from an initial ball that self-organizes in sev

101 Starting from an initial hit molecule, we report its div

102 Starting from an initial structure or set of structures,

103 y a shell assembled by a multiscale process, starting from an integer multiple of 60 viral capsid or

104 ones 41 have been prepared in just two steps starting from anthracene 38.

105 ating the structural identity of metabolites starting from any identified compound.

106 c location of the overlapping deleted region started from approximately 350 kb downstream of GDF6, wh

107 leotide polymorphisms (SNPs) were identified starting from available databases and 260 genotypes anal

108 A wide range of fields, starting from basic research in life sciences and up to

109 emical method to access such hindered amines starting from benchtop-stable iminium salts and cyanohet

110 igh-value specialty chemical building blocks starting from bio-ethanol, which might have an important

111 major congenital anomaly with the follow-up starting from birth that were published in the English l

112 ts along different movement routes in Uganda starting from bordering districts of the DRC to Kampala.

113 d good coverage of the peptide chain termini starting from c'2 and z'2 fragment ions.

114 -step synthesis of a formaldehyde derivative starting from carbon dioxide and hydrogen gas utilizing

115 he synthesis of protected 1,2-amino alcohols starting from carbonyl compounds and alpha-silyl amines.

116 Special catch-up vaccination programs starting from children 2-5 years of age with PCV13 have

117 D along with the error inducing tRNA species starting from Choanoflagellates thus uncovering an impor

118 s of C-C, C-O and C-N bond-forming reactions starting from CO(2) and light.

119 sulfides are regulated across Li-S batteries starting from current collector and active layer coating

120 enopiperidines and bridged benzomorphanones, starting from cyclopropane-fused benzomorphanothiones an

121 neuronal cells compared with ET1 rats alone starting from d1.

122 n tobacco taxes, with annual 12.5% increases starting from December, 2013.

123 al pattern of white matter (WM) degeneration starting from deep brain areas, which is consistent with

124 ed as arising from a multistage process that starts from diamond encapsulation of ferropericlase foll

125 In addition, although cells start from different fates, they rapidly converged on a

126 Several models starting from different initial density values resulted

127 r the first time all aspects of OMS in MOFs, starting from different preparation strategies over theo

128 ctical one-pot procedure for their synthesis starting from easily accessible 1H-pyrazol-5(4H)-ones.

129 motif, common to many cell-surface glycans, starting from either lactose or sucrose as glycosyl dono

130 ) simulations, that magnetotail reconnection starts from electron reconnection in the presence of a s

131 nsformed carbonaceous sulfur hydride system, starting from elemental precursors, with a maximum super

132 Starting from enantioenriched alcohols, the intramolecul

133 Starting from first-principles statistical mechanics, we

134 arious anatomical compartments in the mouse, starting from freshly isolated or frozen cell suspension

135 ] were monitored following temperature jumps starting from fully equilibrated conditions.

136 esis of 5-fluoroalkyl-substituted isoxazoles starting from functionalized halogenoximes is reported.

137 Starting from fundamental thermodynamics and kinetics ph

138 via an alternative cyclopropanation reaction starting from gamma-silyl tertiary alcohols.

139 ylestradiol (EE2) (0.05 and 0.5 mug/kg BW/d) starting from gestational day 6 up to 1 y old according

140 t be indicated for less susceptible bacteria starting from >= 0.125 mg/L to prevent the emergence of

141 We show that starting from hyperpolarized HDO, two-dimensional (2D) p

142 Besides two types of cascade reactions starting from identical materials, through a phenylpropi

143 We report, here, advances starting from identity marking with a genetically encode

144 made to retrieve active state conformations starting from inactive structures, however to date this

145 d tricyclic S-containing indoles is reported starting from indole sulfides tethered with terminal and

146 -amino acids useful for peptide engineering, starting from inexpensive and readily available beta-ala

147 Time to awakening was calculated starting from initial sedation stop following targeted t

148 Here, a top-down process is presented that starts from iron nanoparticles, using dual-metal interbo

149 yclopenta[ b]furan framework was established starting from isatin-derived aldehydes and 2 equiv of 1,

150 urvey results of a real-world social network starting from its point of inception.

151 MEDLINE, Embase, PubMed, and Web of Science starting from Jan 1, 1993, to March 19, 2018.

152 , 963 outpatient adult courses of RT and CRT started from January 7 to June 30, 2019, were evaluated

153 rios for both 4-week and 12-week timeframes, starting from June 26, 2020.

154 Starting from known dual polo-like kinase (PLK)-1-BRD4 i

155 Starting from l-arabinose, key functionalized l- glycero

156 LpxC inhibitors were optimized starting from lead compounds with limited efficacy and s

157 sis of 2,3,4-trideoxy-2,3,4-trifluoroglucose starting from levoglucosan.

158 We track the whole chain of energy flow that starts from light absorption by the individual nanocryst

159 ect access to valuable chiral allylic amines starting from linear or alpha-branched aliphatic primary

160 is related to another fundamental question: Starting from many copies of noisy quantum clocks which

161 ts, haematologists, and vascular specialists starting from May, 2015.

162 lic beta-d-maltose fragment, was synthesized starting from methylpheophorbide-a in seven steps.

163 he assembly of an active Mn(4)CaO(5) cluster starting from Mn(II) and Mn-free PSII.

164 with similar morphology as those formed when starting from monomer solutions.

165 N-C; M=Fe, Co, Ni and Cu) has been developed starting from multivariate metal-organic frameworks (MOF

166 in good yields, using a three-step process, starting from N(tolyl)(3) in a highly divergent manner (

167 ithin different scale of biological material starting from nanometer range to millimeter-sized organs

168 cal synthesis for 1,2,6-thiadiazine 1-oxides starting from NH-sulfonimidamides and propargyl ketones

169 ylation on a multicomponent domino reaction, starting from nonprotected diamines and arylglyoxals.

170 Starting from novel spirocyclic intermediates, we exempl

171 Noticeably, starting from o-nitroaniline derivatives, in the presenc

172 We use simulations starting from one of the largest available real single-c

173 Finally, starting from one or multiple seed genes, a shortest pat

174 ere fed a highly processed, starch-rich diet starting from one week of age through 16 weeks.

175 highly processed, starch-rich diet to calves starting from one week of age through 16 weeks.

176 Starting from one-dimensional genomics and epigenomics d

177 stortion wave is additive-the process always starts from one edge of the helicene and progresses alon

178 ment beyond a 3D printer and a laser cutter, starting from open-source design files and commercially

179 Starting from our previous observations that PP2A (prote

180 Herein, starting from our previous studies, a new family of DDX3

181 eteriorated due to the development of dryout starting from outlet regions and severe two-phase flow i

182 f individual cascading phase transformations starting from parent austenite, and the transformation o

183 ng of polygenic left ventricular hypertrophy starting from patient cells.

184 The second one starts from peptide nucleic acid (PNA) building blocks i

185 generates M1 phases with high surface areas starting from poorly soluble metal oxides.

186 Starting from post-implantation epiblast stem cells (Epi

187 In a wave starting from pouch 2, peridermal cells from the outer s

188 leads to a selective return of BRG1 in cis, starting from pre-existing BRG1 sites that are free of X

189 Starting from previously reported ATM inhibitors, we aim

190 ifunctional compounds, several methodologies starting from propargyl alcohols, acyl derivatives, both

191 Starting from quinoline 2 with weak ATR inhibitory activ

192 unified stochastic modelling approach that, starting from radiation tracks, predicts both the induct

193 Starting from randomly chosen marmoset call features, we

194 em of inferring the full haplotype of a cell starting from read sequencing data is known as haplotype

195 the synthesis of enantiopure InoAz analogues starting from readily available azido glucosides.

196 Starting from readily available compounds as 3-hydroxypr

197 p of the reaction was thoroughly controlled, starting from reagent concentrations and including conju

198 alytically and through extensive simulations starting from real genotypes (UK Biobank, N = 337 K) tha

199 Starting from recent pathological findings, this review

200 Starting from RO6800020 (1), our former gamma-secretase

201 h the experimental results for solid oxides, starting from s- and p-electron oxides.

202 Atomistic molecular dynamics simulations starting from SAS-6 head domain crystallographic structu

203 Rather than starting from scratch, however, it's sometimes possible

204 Starting from simple carboxylic acid building blocks, th

205 on of diverse and valuable amine derivatives starting from simple compounds.

206 ions, in the absence of expensive catalysts, starting from simple reagents, in good to excellent yiel

207 nocatalyzed annulation/O-alkylation strategy starting from simple substrates.

208 cinal alkaloids hyoscyamine and scopolamine, starting from simple sugars and amino acids.

209 However, most current protocols start from single cells suspended in Matrigel, which can

210 recipitates on the microscale formed by MICP starting from single ureolytic E. coli MJK2 cells in 25

211 esis proceeds via a cation-exchange reaction starting from single- and multi-layer Ag(2)S and going t

212 When starting from single-stranded-DNA, DNA is first converte

213 Starting from six commercially available amino acids or

214 incorporated as we go through the pipeline, starting from SNPs and ending at network overlap analyse

215 alide salts, which forces the film formation starts from solution surface.

216 atogenesis and the following spermatogenesis started from spermatogonium is probably regulated by dif

217 How circuits assemble starting from stem cells is a fundamental question in de

218 Starting from such a critical analysis and integrating r

219 Here, we start from the hypothesis that the genetic identity of n

220 We start from the premise that any self-organising system c

221 Protection with lanadelumab started from the first dose and continued throughout the

222 Initially, we started from the synthesis of 4-((3-((4-methoxyphenyl) t

223 structures are accessed in two to four steps starting from the (mostly) commercially available aldehy

224 Starting from the 1,2-bis(N-heterocyclic silylenyl) 1,2-

225 s (MD) and metadynamics (metaMD) simulations starting from the 3.1- angstrom X-ray structure of kappa

226 Here, starting from the addition of small monomers in the PbI(

227 N-formyldemecolcine in Nicotiana benthamiana starting from the amino acids phenylalanine and tyrosine

228 modeling and molecular dynamics simulations, starting from the available crystal structures of HCV NS

229 Starting from the beta-adrenoceptor agonist isoprenaline

230 Here, starting from the chemical master equation describing pr

231 esters could be obtained using this protocol starting from the corresponding trialkyl phosphites and

232 robustness of multilayer biological networks starting from the degree distributions within and betwee

233 using this straightforward one-pot synthesis starting from the easily accessible 1-aminoPDI.

234 , to reach the prefusion state collectively, starting from the experimentally observed half-zippered

235 t interaction via a reverse route (SMSIR) by starting from the final morphology of SMSI (fully-encaps

236 ity-specific representations were detectable starting from the first implementation trial and continu

237 or the first four steps of MbA biosynthesis, starting from the flavonol precursor myricetin, have rec

238 Starting from the full range of each gate voltage, our m

239 tes, which is why we here cover the progress starting from the fundamental electrode/electrolyte requ

240 from the perspective of synthetic chemistry: starting from the fundamentals regarding algorithms and

241 y and facilitates the magnetization reversal starting from the grain boundaries.

242 nd demonstrates that the current practice of starting from the highest potency binder is an ineffecti

243 Starting from the initial distribution of eggs, we estim

244 sm has been proposed for the flagellar motor starting from the inner membrane, with the addition of e

245 nt action to improve prescription practices, starting from the integration of WHO treatment recommend

246 Next, starting from the inward-facing conformation of EcNhaA,

247 the landmark discoveries in the mTOR field, starting from the isolation of rapamycin to the molecula

248 method applies a network diffusion approach, starting from the known disease genes in a heterogenous

249 Starting from the Kubo formula, we derive the analytical

250 Starting from the late 90s, we provide an overview of hi

251 ity is self-generated as a polarisation wave starting from the leading edge of the monolayer and prog

252 Sequential developmental events, starting from the moment of fertilization, are crucial f

253 Starting from the natural history of the disease in huma

254 Starting from the observation that the sulfated glycosam

255 each of the two known states of TtNapA when starting from the opposite state, in support of the rock

256 Starting from the OX1R and OX2R crystal structures bound

257 19 (but not 13) 3'-terminal mRNA nucleotides starting from the P site.

258 significant healing of erosions and plaques starting from the peripheral aspect within 1 to 2 weeks

259 Starting from the plasma membrane with the recognition o

260 The descriptors we evaluate include those starting from the position-specific scoring matrix (PSSM

261 for the inhibition of TRPV4, was identified starting from the previously reported pyrrolidine sulfon

262 Starting from the putative muurolane biological precurso

263 Starting from the recently reported cryogenic electron m

264 MC implants are placed in various locations, starting from the region near where the chordae tendinea

265 Starting from the respective native starches, the modifi

266 Starting from the same data, the use of different acquis

267 Starting from the same kind of data we propose an altern

268 Starting from the same material, it is possible to prepa

269 Starting from the same monoboronic ester intermediates,

270 Starting from the scaffold of a novel class of norovirus

271 Starting from the spectroscopically observed 1,2-mu-pero

272 Starting from the structure models, the nature of chemic

273 Starting from the structure of a known NTSR1 agonist, a

274 Starting from the transcriptome of auxin-deregulated emb

275 lematic circuits of solid-state electronics: starting from the transistor and progressing to ring osc

276 Starting from the vent, Shivlinga's geomicrobiology was

277 species (ROS) increased in human donor lungs starting from the warm-ischemia phase and were associate

278 step cross-coupling and cyclization approach starting from the zincated 4,6-dichloropyrimidine, gave

279 The reaction starts from the coupling between N-tosylhydrazones and 2

280 inspired by Bayesian non-parametrics, which starts from the direct analysis of the observed photon c

281 In chicken dorsal skin, feather formation starts from the midline; then the morphogenetic wave pro

282 The model starts from the photons emitted by a display, which pass

283 o predict the targets of a set of microRNAs, starting from their expression profile.

284 This method starts from thermally drawing SnSe into a flexible fiber

285 Starting from these preliminary results, we report herei

286 Starting from these simulations, we subsequently seed cl

287 Starting from this statement we designed a circuit that

288 d epi-ampelomin B, D, and E was accomplished starting from toluene, through a chemoenzymatic sequence

289 choline (POPC) of hexamers of these peptides starting from transmembrane orientations at neutral pH (

290 e to create indefinitely expanding organoids starting from tumor tissue of individuals suffering from

291 Starting from two peptides that inhibit the NGF/TrkA int

292 Starting from two-band considerations, we develop the co

293 Electron transfer starts from ultrafast reduction of excited FAD to FAD(*-

294 ces, self-replication in the present systems start from units containing only a single nucleobase.

295 achieved in eight steps and 9% overall yield starting from (+)-valencene, leading to a reassignment o

296 t their existing dose as blinded study drug; starting from week 14, patients assigned to continue met

297 en propose a selection of remaining defects, starting from what we know and going toward what is stil

298 tion of complex polysubstituted ring systems starting from widely available heterocyclic amine nucleo

299 Starting from wild-type rats, knockout of tyrosine hydro

300 nd applying them to optimize atom positions, starting from X-ray diffraction (XRD)-determined atomic