ライフサイエンスコーパス: stem cell biology

1 i3bp) as a protein important for mesenchymal stem cell biology.

2 s is an important issue in developmental and stem cell biology.

3 l uptake into cells, and also play a role in stem cell biology.

4 e expression regulation in developmental and stem cell biology.

5 echanism in animal body plan development and stem cell biology.

6 nstrate the application of these browsers to stem cell biology.

7 umorigenesis, response to therapy and cancer stem cell biology.

8 to a better understanding of human prostate stem cell biology.

9 is a key outstanding question of systems and stem cell biology.

10 ates, functioning in embryogenesis and adult stem cell biology.

11 or miRNA is emerging as an important tool in stem cell biology.

12 ons to regenerate, as well as innovations in stem cell biology.

13 n experiments was accounted for by facets of stem cell biology.

14 ideal model for this understudied aspect of stem cell biology.

15 attempt to understand how Notch functions in stem cell biology.

16 , together with RNAi, revealed gene roles in stem cell biology.

17 ing has provided unprecedented insights into stem cell biology.

18 has been greatly aided by recent advances in stem cell biology.

19 s but has not been studied in the context of stem cell biology.

20 y desirable in biomedical research including stem cell biology.

21 artilage and an important regulator of crypt stem cell biology.

22 has seen remarkable advances in the field of stem cell biology.

23 reatment, are poised to benefit greatly from stem cell biology.

24 ls (GSCs) have served as a paradigm in niche-stem cell biology.

25 excellent system for in vivo study of adult stem cell biology.

26 a poorly understood but important problem in stem cell biology.

27 ency are rather poorly understood aspects of stem cell biology.

28 similarly controls normal mammary epithelial stem cell biology.

29 and implicates its potential significance in stem cell biology.

30 own for their role in cancer development and stem cell biology.

31 ty is a fundamental issue in both cancer and stem cell biology.

32 ting a combination of tissue engineering and stem cell biology.

33 ated function of Norrin in regulating cancer stem cell biology.

34 form resource for studying hematopoiesis and stem cell biology.

35 idated by considering cancer as a problem in stem cell biology.

36 differentiation are two central questions in stem cell biology.

37 has been one of the most productive areas of stem cell biology.

38 posed ancestral functions of PUF proteins in stem cell biology.

39 epigenetic research on our understanding of stem cell biology.

40 ns between PLZF and Rb could be important in stem cell biology.

41 ding the role of mitochondrial metabolism in stem cell biology.

42 ovide much needed insight into understanding stem cell biology.

43 fundamental challenges in developmental and stem cell biology.

44 he important role of membrane trafficking in stem cell biology.

45 tudy of regeneration, tissue homeostasis and stem cell biology.

46 ertaining to emerging topics of interest for stem cell biology.

47 adult heart disease and the growing field of stem cell biology.

48 nd the understanding of crucial questions of stem cell biology.

49 division and their broader implications for stem cell biology.

50 inent role in controlling several aspects of stem cell biology.

51 study intrinsic mechanisms of hematopoietic stem cell biology.

52 these interactions is key for understanding stem cell biology.

53 chanisms of action of circRNAs, let alone in stem cell biology.

54 ll self-renewal is a fundamental question in stem cell biology.

55 s in neutrophil maturation and hematopoietic stem cell biology.

56 e adult stem cell niches and their impact on stem cell biology.

57 perimental model for the study of epithelial stem cell biology.

58 of maintaining mitochondrial plasticity for stem cell biology.

59 out the role of this unusual carbohydrate in stem cell biology.

60 newal is fundamental to the understanding of stem cell biology.

61 ndation for a more detailed understanding of stem cell biology.

62 er inhibition and provides insights into CML stem cell biology.

63 ng fields such as cancer, developmental, and stem cell biology.

64 an important role in tissue homeostasis and stem cell biology.

65 rface marker, and peculiarly in the field of stem cell biology.

66 dissecting the functions of Fzd subtypes in stem cell biology.

67 ew light on the role of PML in senescence or stem cell biology.

68 can function as epigenetic reprogrammers in stem cell biology.

69 ip systems based on cardiac cell culture and stem cell biology.

70 reimplantation development to instruct human stem cell biology.

71 research concerning Heart-on-a-chip based on stem cell biology.

72 as control of organ size, regeneration, and stem cell biology.

73 ata into knowledge of both developmental and stem cell biology.

74 biology, pharmacology, cancer diagnosis and stem cell biology.

75 egulator, with potential roles in cancer and stem cell biology.

76 y, microbiology, immunology, hematology, and stem cell biology.

77 function in fields such as developmental and stem cell biology.

78 lization for gene-repression applications in stem cell biology.

79 trol of pluripotency is of great interest in stem cell biology.

80 d to DDT were used to evaluate the impact on stem cell biology.

81 modifications that regulate skeletal muscle stem cell biology.

82 sed in research in developmental, cancer and stem cell biology.

83 tein that goes beyond its well-known role in stem cell biology.

84 acteristics remain a fundamental question in stem cell biology.

85 netic regulation have important functions in stem cell biology, although the interactions between the

86 onicle of concepts in the field of epidermal stem cell biology and a historic look at their developme

87 A better understanding of adipose stem cell biology and adipogenesis may lead to novel str

88 Up to present, SPR application in stem cell biology and biomedical sciences was underused.

89 antigen Sca-1 is implicated in murine cancer stem cell biology and breast cancer models, but the role

90 logy, driven both by the intense activity in stem cell biology and by the emergence of systems biolog

91 hmC and TET proteins have been implicated in stem cell biology and cancer, but information on the gen

92 rowth promoting programs relevant to mammary stem cell biology and cancer.

93 Research in stem cell biology and cell reprogramming is rapidly adva

94 lays a crucial role in embryonic and somatic stem cell biology and cell reprogramming.

95 We also discuss how progress in stem cell biology and cellular reprogramming has enabled

96 ltiple CH genes are key regulators of neural stem cell biology and converge in human transcriptional

97 particularly in the fields of neuroscience, stem cell biology and developmental biology.

98 Understanding urothelial stem cell biology and differentiation has been limited b

99 Recent advances in stem cell biology and direct reprogramming, or transdiff

100 l signaling pathways involved in brain tumor stem cell biology and discuss how targeting these molecu

101 lored the role of TSC1 in various aspects of stem cell biology and dissected the extent to which TSC1

102 Despite its well characterized role in stem cell biology and during early development, the role

103 Advances in stem cell biology and engineering allow for the generati

104 enome to facilitate further understanding of stem cell biology and engineering of stem cells for ther

105 , and meta-regression to study the impact of stem cell biology and experimental design on motor and s

106 These data have implications for stem cell biology and for the analysis of the oncogenici

107 is pathway could be of importance for neural stem cell biology and for understanding the pathogenesis

108 ique potential to address diverse aspects of stem cell biology and gametogenesis.

109 important implications for gastrointestinal stem cell biology and H pylori-induced gastric pathology

110 u represents a major step forward in gastric stem cell biology and has potential implications for gas

111 rrent understanding of how Cripto-1 controls stem cell biology and how it integrates with other major

112 out how H. pylori may adapt to and influence stem cell biology and how its intracellular residency co

113 that propose a role for calcium signaling in stem cell biology and human developmental disorders.

114 Here we highlight the importance of mice in stem cell biology and in bringing the world one step clo

115 cription factor having a central function in stem cell biology and in human cancers.

116 play important roles in normal hematopoietic stem cell biology and in the development of both acute a

117 technology has greatly advanced the field of stem cell biology and nurtured our hope to create patien

118 oundation for new avenues of inquiry into GI stem cell biology and of OSTERIX's therapeutic and diagn

119 ndamental questions about human development, stem cell biology and organ regeneration.

120 gies ex vivo Recent advances in the field of stem cell biology and organoid culture systems allow the

121 ving subjects is essential for understanding stem cell biology and physiology.

122 ssion, Wnt signaling in development, cancer, stem cell biology and regeneration, and therapeutics tha

123 unctions of KLFs in mammalian embryogenesis, stem cell biology and regeneration, as revealed by studi

124 rtant model for studies of axial patterning, stem cell biology and regeneration.

125 air follicles are a widely studied model for stem cell biology and regeneration.

126 Research discoveries in the fields of stem cell biology and regenerative medicine are beginnin

127 Rapid advances in stem cell biology and regenerative medicine have opened

128 em cells (iPSCs) are poised to revolutionize stem cell biology and regenerative medicine research, br

129 pluripotent state of ESCs is a key issue in stem cell biology and regenerative medicine, and consequ

130 ) have a number of potential applications in stem cell biology and regenerative medicine, including p

131 poised to have substantial implications for stem cell biology and regenerative medicine.

132 aise previously undescribed implications for stem cell biology and regenerative medicine.

133 lopment remains a fundamental goal impacting stem cell biology and regenerative medicine.

134 s well as applications of these processes to stem cell biology and regenerative medicine.

135 various studies, especially in the fields of stem cell biology and regenerative medicine.

136 re studies that enhance our understanding of stem cell biology and repair mechanisms will provide a p

137 Today, advances in the fields of stem cell biology and signal transduction are being inte

138 substantial advances in our understanding of stem cell biology and some recent important advances in

139 provide new insights with regard to leukemic stem cell biology and suggest possibilities for the deve

140 Profound advances in human stem cell biology and technology, tissue engineering and

141 ur current understanding of small intestinal stem cell biology and the current tools available for st

142 ve intriguing implications for understanding stem cell biology and the evolution of pathogen resistan

143 o unveil adipose developmental cues, adipose stem cell biology and the regulators of adipose tissue h

144 for both niche plasticity in other areas of stem cell biology and the therapeutic use of neural stem

145 ate, and may ultimately be useful to in vivo stem cell biology and therapy.

146 matopoiesis has long served as a paradigm of stem cell biology and tissue homeostasis.

147 order Tricladida, are experimental models of stem cell biology and tissue regeneration.

148 models to study the molecular mechanisms of stem cell biology and tissue regeneration.

149 em cell activity is central to understanding stem cell biology and to developing strategies for the t

150 ning stem cells is critical to understanding stem cell biology and to using stem cells in future rege

151 oscience, hematology, developmental biology, stem cell biology and transgenesis are rapidly emerging.

152 Basic stem cell biology and transplant biology aim to uncover

153 clinical implications in the field of human stem cell biology and transplantation.

154 basic cellular and developmental processes, stem cell biology and tumorigenesis.

155 Despite the wealth of research on stem-cell biology and therapy, there have been few advan

156 rocesses including cellular differentiation, stem cell biology, and cancer development.

157 clearly influence tumorigenesis, pluripotent stem cell biology, and epidermal cell lineage decisions,

158 tosis and promotion of proliferation, cancer stem cell biology, and epithelial-to-mesenchymal transit

159 eshaped our approach to biomedical research, stem cell biology, and human genetics.

160 erizing the effect of this oncogene on human stem cell biology, and in defining its contribution to t

161 as been eclipsed by the rise of genomics and stem cell biology, and in part because it has seemed les

162 ations has dramatically altered the field of stem cell biology, and it has been a major focus of rese

163 ecules will likely provide new insights into stem cell biology, and may ultimately contribute to effe

164 may be important for embryonic development, stem cell biology, and tumor growth.

165 A variety of applications in cancer biology, stem cell biology, apoptosis studies, and high throughpu

166 s contributions to epigenetic regulation and stem cell biology are less explored.

167 NA processing machinery in the regulation of stem cell biology are not well understood.

168 Current models of stem cell biology assume that normal and neoplastic stem

169 retina as an ideal model for studying adult stem cell biology at single cell resolution.

170 t lead to CH, specifically in the context of stem cell biology, based on our current understanding of

171 HSCs represent a paradigm for the study of stem-cell biology, because robust methods for prospectiv

172 The convergence of stem cell biology, bioengineering, and gene editing tool

173 es in biomaterial synthesis and fabrication, stem cell biology, bioimaging, microsurgery procedures,

174 hnological advances in micro/nanotechnology, stem cell biology, biomaterials and tissue decellulariza

175 A central unanswered question in stem cell biology, both in plants and in animals, is how

176 profound understanding of the principles of stem cell biology, but also of its potential pitfalls.

177 revealed a fusion of infection biology with stem cell biology by demonstrating developmental reprogr

178 Epigenetic mechanisms play critical roles in stem cell biology by maintaining pluripotency of stem ce

179 ps, smart algorithms), alongside advances in stem cell biology, cell encapsulation methodologies, and

180 The recent confluence of advances in stem cell biology, cell signaling, genome and computatio

181 e dataset, and led to insights on intestinal stem cell biology, cell type-specific organelle features

182 unctional evidence linking Sox proteins with stem cell biology, cellular reprogramming, and disease w

183 tinued progress in understanding basic human stem cell biology, combined with a better handle on the

184 s to understand how iron exposure influences stem cell biology could be enhanced by establishing plat

185 ntal cues involved in retinal generation and stem cell biology, coupled with extensive surgical resea

186 le to mapped gene expression measurements in stem cell biology, developmental biology, cancer biology

187 iples that have significant implications for stem cell biology, developmental neurobiology, neural pl

188 erve as valuable reagents for studying colon stem cell biology, differentiation, and pathogenesis.

189 have been made in the field of hematopoietic stem cell biology during the past year.

190 KLFs have diverse functions in stem cell biology, embryo patterning, and tissue homoeos

191 Given the rapidly advancing field of stem cell biology, EMBs were subsequently seeded with th

192 ey insights into mammalian developmental and stem cell biology, emphasizing the analytical approaches

193 advances made regarding the role of PRMTs in stem cell biology, epigenetics, splicing, immune surveil

194 demethylase LSD1 plays an important role in stem cell biology, especially in the maintenance of the

195 many questions in both germ cell biology and stem cell biology fields.

196 udy of regeneration, tissue homeostasis, and stem cell biology for over a century, but they have not

197 stem cells cautions against inferring adult stem-cell biology from embryonic studies, and has direct

198 Stem Cell Symposium to discuss 'Quantitative stem cell biology: from molecules to models'.

199 In February 2010, researchers interested in stem cell biology gathered in Keystone, Colorado, USA to

200 a critical perspective on recent advances in stem cell biology, gene therapy, cell cycle regulation a

201 forts in nonmammalian and human development, stem cell biology, genetics, materials science, bioengin

202 For motor outcome, facets of stem cell biology had little detectable effect.

203 years, a new subdiscipline of computational stem cell biology has emerged that synthesizes the model

204 Stem cell biology has experienced explosive growth over

205 s (EPCs) in tandem with emerging concepts in stem cell biology has generated enormous interest and ex

206 In this Perspective, we consider how cardiac stem cell biology has led us into clinical trials, and w

207 Understanding epithelial stem cell biology has major clinical implications for th

208 The role of ROS in stem cell biology has not been fully illustrated and und

209 Stem cell biology has the potential to yield new therapi

210 The field of stem-cell biology has been catapulted forward by the sta

211 Human genetics and stem cell biology have advanced neurobiology for neurode

212 Advances in developmental and stem cell biology have allowed the development of cell-r

213 ibility and fundamental aspects of embryonic stem cell biology have been localized in a genetic conte

214 ces in materials, microscale technology, and stem cell biology have enabled the construction of 3D ti

215 Recent developments in stem cell biology have enabled the study of cell fate de

216 Recent developments in stem cell biology have generated much excitement for bet

217 rs ago, it is only recently that advances in stem cell biology have given new impetus to the "cancer

218 iew how recent advances in developmental and stem cell biology have made it possible to generate comp

219 Recent advancements in the field of stem cell biology have provided a source of human-based

220 Recent advances in epithelial stem cell biology have resulted in the isolation of hair

221 Recent developments in our understanding of stem-cell biology have profoundly influenced the practic

222 strophies, hematopoiesis, cancer, and neural stem cell biology, highlighting the importance of this k

223 ospective studies of leukemia initiation and stem cell biology in a genetic subtype of poor prognosis

224 p53, homologs of which have no known role in stem cell biology in any invertebrate examined thus far.

225 to be practically useful in studying neural stem cell biology in health and disease.

226 nessing substantial strides in understanding stem cell biology in humans; however, major disappointme

227 anisms that regulate tissue regeneration and stem cell biology in these organisms.

228 ion of neuronal lineages and, more recently, stem cell biology in vertebrates.

229 eld at the intersection of developmental and stem cell biology in which a somatic cell is stably repr

230 a transcription factor widely implicated in stem cell biology, in CNS myelination and remyelination.

231 ficant impact in studying various aspects of stem cell biology including the phenomenon of stem cell

232 ights of general relevance to other areas of stem cell biology including the role of cellular interac

233 cal approaches and engineering principles in stem cell biology, including culture systems, preclinica

234 A better understanding of stem cell biology, including embryonic and adult stem ce

235 These deficits affect multiple aspects of stem cell biology, including quiescence, renewal, and di

236 plications for the role of Myc in cancer and stem cell biology, including that of induced pluripotent

237 ress we have made in understanding epidermal stem cell biology is discussed in this article.

238 An important question in stem cell biology is how a cell decides to self-renew or

239 Therefore, a critical question in stem cell biology is how stem cells escape cell division

240 A fundamental yet unexplored question in stem cell biology is how the fate of tissue stem cells i

241 tors, including microRNAs, whose key role in stem cell biology is just emerging.

242 Information about sertuins in stem cell biology is scarce.

243 Stem cell biology is scientifically, clinically, and pol

244 The central tenet of stem cell biology is that within tissues there reside st

245 A key issue in stem cell biology is the differentiation of homogeneous

246 A major goal in stem cell biology is to gain a sufficient understanding

247 A fundamental goal of developmental and stem cell biology is to map the developmental history (o

248 A central issue in stem cell biology is to understand the mechanisms that r

249 A fundamental issue in stem cell biology is whether adult somatic stem cells ar

250 A central question in stem cell biology is whether organ homeostasis is mainta

251 ental yet essentially unexplored question in stem cell biology is whether the stem cell cycle has spe

252 w we discuss some general concepts regarding stem cell biology learned from the study of HSCs with a

253 A major challenge in neuronal stem cell biology lies in characterization of lineage-sp

254 tissue engineering and our understanding of stem cell biology may provide a lifelong solution to the

255 The expanding research field of cancer stem-cell biology may offer a novel clinical apparatus t

256 stem (iPS) cells have brought the science of stem cell biology much closer to clinical application fo

257 essential roles in controlling hematopoietic stem cell biology, myeloid and lymphoid differentiation

258 Areas as diverse as stem cell biology, neurobiology, metabolism, and immunit

259 helial morphogenesis, cytoskeletal dynamics, stem cell biology, neurobiology, physiology, etc.

260 otential importance of AC133 to the field of stem cell biology, nothing is known about the transcript

261 UDH biology, glandular lumen formation, and stem cell biology of the mammary gland.

262 Recent advances in genetics and stem cell biology offer new prospects for cell-based mod

263 Stem cell biology offers advantages to investigators see

264 This review summarizes recent advances in stem cell biology, outlines ongoing clinical trials and

265 siderable advances in the field of embryonic stem cell biology, particularly in the area of pluripote

266 decade with respect to our understanding of stem cell biology, progress has been limited in the deve

267 g in evolutionary and developmental biology, stem cell biology, regeneration and disease.

268 an emerging model species in fields such as stem cell biology, regeneration and evolutionary biology

269 inthes are excellent models for the study of stem cell biology, regeneration and the regulation of sc

270 luence cell behavior, and have importance to stem cell biology, regeneration and transplantation, and

271 s a unifying theme in embryonic development, stem cell biology, regeneration, and cell competition.

272 verse fields, most notably developmental and stem cell biology, regenerative medicine, and cancer bio

273 ll function has significant implications for stem cell biology, repair of lung injuries, and diseases

274 ein arginine methyltransferase with roles in stem cell biology, reprograming, cancer and neurogenesis

275 ng discoveries made recently in the field of stem cell biology, researchers now have improved tools t

276 ypes and that hierarchical models of mammary stem cell biology should encompass bidirectional interco

277 k in limb regeneration, fetal wound healing, stem cell biology, somatic nuclear transfer, and tissue

278 ranscription, the cell cycle, cell death and stem cell biology, studies of metazoan development have

279 Important issues in stem cell biology, such as stem cell niche, homing, and

280 he major advances in fundamental and applied stem cell biology that emerged.

281 has seen incredible advances in the field of stem cell biology that have greatly improved our underst

282 In particular, research in stem cell biology, the cardiomyocyte lineage, and the in

283 In stem cell biology, the dynamic addition and removal of 5

284 e studied AS in a powerful in vivo model for stem cell biology, the planarian Schmidtea mediterranea.

285 h the behavior expected for a tumor based on stem cell biology; this finding has diagnostic and thera

286 plications to drug delivery, drug discovery, stem cell biology, tissue engineering and regenerative m

287 naling pathway that plays important roles in stem cell biology, tissue homeostasis, and cancer develo

288 rugs and the application of gene therapy and stem cell biology to address the genetic abnormalities.

289 slate recent advances in induced pluripotent stem cell biology to clinical regenerative medicine ther

290 ion of molecularly designed biomaterials and stem cell biology to develop stable tissue regeneration.

291 g approaches and the emergent application of stem cell biology to overcome spinal cord injury.

292 For the field of pluripotent stem cell biology to realize its promising future, curre

293 uring embryonic development and for applying stem cell biology to regenerative medicine and disease m

294 of viable intact cells required to translate stem cell biology to regenerative medicine in a simple l

295 helium as well as factors involved in breast stem cell biology tumor initiation and progression.

296 The study of epithelial stem cell biology was aided by the ability to visualize

297 lved, will soon provide a further impetus to stem cell biology with far reaching applications.

298 To connect the transcriptome and stem cell biology, with potential clinical applications,

299 orphogens, which are essential regulators of stem cell biology, yet the structural basis of Wnt signa

300 t and function, CNS immune surveillance, and stem cell biology, yet we know surprisingly little about