ライフサイエンスコーパス: stem cell factor

1 BMC) after priming with fibroblast membranal stem cell factor.

2 YAP1 gene encodes a potent new oncogene and stem cell factor.

3 w stromal cells with IL-15, IL-7, Flt3L, and stem cell factor.

4 ulin-like growth factor-I and membrane-bound stem cell factor.

5 eptor tyrosine kinase, KIT, the receptor for stem cell factor.

6 r mast cells were exposed to the Kit ligand, stem cell factor.

7 ated with mutations in KIT, the receptor for stem cell factor.

8 te-macrophage colony-stimulating factor plus stem cell factor.

9 al stromal cells supplemented with IL-15 and stem cell factor.

10 tro in response to IL-7, erythropoietin, and stem cell factor.

11 rously than EL cells in response to IL-3 and stem cell factor.

12 t auto-phosphorylation induced by the ligand stem cell factor.

13 had relatively higher levels of M-CSF and of stem cell factor.

14 cell line supplemented with human G-CSF and stem cell factor.

15 to granulocyte colony-stimulating factor and stem cell factor.

16 ember, APLP2, showed no correlation to these stem cell factors.

17 epithelial differentiation and inhibitors of stem cell factors.

18 Stem cell factor (10 ng/mL) alone was unable to induce m

19 stored Foxn1 expression along with ccl25 and stem cell factor A number of putative targets of miR-205

20 In contrast, the cytokine stem cell factor, a regulator of mast cell differentiati

21 educed colony-forming activity and increased stem-cell-factor activation of the phosphoinositide-3-ki

22 Treatment with stem cell factor/AMD3100 led to a greater increase in ci

23 x N1 (Foxn1), and its two regulated targets, stem cell factor and ccl25, following stress.

24 th and retention factors, most significantly stem cell factor and CXCL12, which act preferentially to

25 ective Erk and Akt activation in response to stem cell factor and diminished thrombopoietin-evoked Er

26 -15Ralpha(-/-) mice were cultured with IL-7, stem cell factor and flt3 ligand, followed by IL-15, the

27 dgehog, bone morphogenetic protein 4 (BMP4), stem cell factor and hypoxia.

28 ing their immortalization in the presence of stem cell factor and IL-3.

29 Stem cell factor and IL-4 upregulated C5aR2 expression o

30 Stem cell factor and IL-6 were found to be minimal requi

31 te into CCA tumor microenvironment via c-Kit/stem cell factor and increase tumor progression, angioge

32 Stem cell factor and its receptor, KIT, are central to m

33 ggests a possible competition for the ligand Stem cell factor and offers the chance of curing early-s

34 activates transcription of the gene encoding stem cell factor and that mice lacking the cognate recep

35 volunteers were cultured in the presence of stem cell factor and thrombopoietin.

36 epletion of C/EBPdelta reduced expression of stem cell factors and stemnness markers, sphere formatio

37 thrombopoietin synergize with low levels of stem-cell factor and fibronectin to sustain HSC self-ren

38 expansion in the presence of erythropoietin, stem cell factor, and dexamethasone.

39 wth factors, basic fibroblast growth factor, stem cell factor, and endothelin-3, along with exposure

40 actor, alpha-melanocyte stimulating hormone, stem cell factor, and fibroblast growth factor-2 in skin

41 of cytokines (interleukin-7, interleukin-15, stem cell factor, and fms-like tyrosine kinase-3 ligand)

42 Our previous work demonstrated that BMP4, stem cell factor, and hypoxia act in concert to promote

43 mbinations of dexamethasone, erythropoietin, stem cell factor, and interleukin-3.

44 early hemopoietic cytokines such as FLT3-L, stem cell factor, and M-CSF maybe relevant in LCH pathog

45 ial growth factor, fibroblast growth factor, stem cell factor, and stromal cell-derived factor-1, whe

46 B is required for mast cell migration toward stem cell factor, and that TGF-beta1 reduced this migrat

47 promoted CSC self-renewal, the expression of stem cell factors, and CSC proliferation.

48 cl-2 upregulation, which was blocked by anti-stem cell factor antibody alone, the phosphatidylinosito

49 Erythropoietin and stem cell factor are the key cytokines that regulate ear

50 locyte-colony-stimulating factor (G-CSF) and stem cell factor at days 17 to 20 of parabiosis and were

51 Inhibition of CCA stem cell factor blocked MC migration and MC/EMT/ECM in

52 it expression when administered 3 days after stem cell factor, by which time surface Kit levels had r

53 Samd14-Enh stimulated stem cell factor/c-Kit signaling, which promotes erythro

54 matopoietic stem/progenitor cell regulation (stem cell factor/c-Kit), and c-Kit rescued Samd14 loss-o

55 m that depends, at the molecular level, on a stem cell factor/c-kit-mediated signaling axis.

56 ore, MSCs enhanced CSC proliferation via the stem cell factor/cKit and SDF1/CXCR4 pathways (P<0.0001)

57 Conversely, in the absence of IL-7 and stem cell factor, cNK cells were generated but ILC22 cel

58 the differentiation of interleukin-3 (IL-3)/stem cell factor (colony-forming unit [CFU]-IL3)-driven

59 fetal liver cells (FLC), erythropoietin- or stem cell factor-dependent Akt activation is greatly red

60 Moreover, proper stem cell factor-dependent cofilin activation via dephos

61 fibroma genesis, delineate the physiology of stem cell factor-dependent hematopoietic cells and their

62 The stem cell factor-dependent multipotent progenitor cell l

63 tor, growth hormone, parathyroid hormone, or stem cell factor each stimulates greater donor osteoblas

64 Treatment with the stem cell factor enhanced transcript levels of STIM1 and

65 and (CXCL)12-abundant reticular (CAR) cells, stem cell factor-expressing cells, nestin-expressing cel

66 and progenitor cells and reduced CXCL12 and stem cell factor expression in CAR cells but did not ind

67 AR cell development, upregulating CXCL12 and stem cell factor expression.

68 -fold reduction in response to a cocktail of stem cell factor, flt3 ligand, and thrombopoietin.

69 red on MS-5 stromal cells in the presence of stem cell factor, Flt3-L, interleukin 7 (IL-7), and IL-3

70 d up to 2 hours after their stimulation with stem cell factor, Fms-like tyrosine kinase 3 ligand, int

71 combinant mouse FLT3-L and recombinant mouse stem cell factor followed by recombinant mouse IL-5 alon

72 n vivo to directly activate transcription of stem cell factor FoxD3, initiating the neural crest prog

73 mal stem cell proliferation via its putative stem cell factor function, but it is not known if BMI1 m

74 rent time points in controls (n=10) and upon stem cell factor gene transfer (n=13) after myocardial i

75 Stem cell factor gene transfer induces c-kit(+) stem/pro

76 iated lncRNA activated the promoters of core stem cell factor genes and enhanced fibroblast reprogram

77 mma(null)) mouse strain that expressed human stem cell factor, granulocyte-macrophage colony-stimulat

78 e-bound tyrosine kinase and the receptor for stem cell factor, has also been shown to play a critical

79 d C3orf58 as a novel hypoxia and Akt induced stem cell factor (HASF) secreted from mesenchymal stem c

80 overexpression of membrane-associated human stem cell factor (hSCF) enhances epicardial activation,

81 immunodeficient common gamma chain-deficient stem cell factor (huNSG) mice exhibited robust engraftme

82 on mutations in Kit receptors or Kit ligand (stem cell factor), ICC failed to develop in various regi

83 h of myeloid progenitors in an interleukin 3/stem cell factor (IL-3/SCF)-dependent manner in vitro wh

84 ony-stimulating factor or the combination of stem cell factor, IL-3, and IL-6.

85 Furthermore, in the presence of the stem cell factors, IL-33 did induce an MK2/3-, ERK1/2- a

86 pression of human GM-CSF, interleukin-3, and stem cell factor in a NOD/SCID-IL2Rgamma(null) backgroun

87 o measured significantly increased IL-16 and stem cell factor in KC saliva samples compared to health

88 hh produced in the dorsal region of the AGM, stem cell factor in the ventral and lateral regions, and

89 rine and human MCs and a regulatory role for stem cell factor in their expression.

90 growth factor, stromal-derived factor 1, and stem cell factor in tumor xenografts.

91 adjacent TBs and that both organs coexpress stem cell factors in subsets of label-retaining cells.

92 and ALDH1, the most significantly activated stem-cell factors in DCIS stem-like cells, are direct ta

93 vascular cell adhesion molecule 1, SDF-1 and stem cell factor increased phospho-c-kit levels, and AMD

94 Moreover, growth factors including stem cell factor increased transcription of the Mcl-1 ge

95 Furthermore, stem cell factor induced LHPC proliferation, whereas gra

96 ted mast cells, absence of P38alpha inhibits stem cell factor-induced activation of Akt and ERK, whic

97 ith mature cells was selectively enhanced by stem cell factor-induced activation of GSK3beta.

98 ll progenitor cells as well as by regulating stem cell factor-induced migration of fully differentiat

99 mily genes and of transcriptional targets of stem cell factor-induced signaling.

100 Stem cell factor-induced survival of TC-32 cells was als

101 existence of a tissue microenvironment where stem cell factors influence cell survival, inflammation,

102 re performed with CCA cells treated with the stem cell factor inhibitor.

103 t whereas Rac1 activity is up-regulated upon stem cell factor, integrin, or CXCL12 stimulation, R-Ras

104 or four cytokines (Flt3L + thrombopoietin + stem cell factor + interleukin 3).

105 , ESCs were cultured in methylcellulose with stem cell factor, interleukin (IL)-3, and IL-6.

106 ole for 3 hematopoietic stem cell cytokines: stem cell factor, interleukin-3, and stromal derived fac

107 ne-bound stem cell factor, releasing soluble stem cell factor into the cell culture supernatant at a

108 Stem cell factor is another important hematopoietic cyto

109 The KIT receptor whose ligand is the stem cell factor is necessary for mast cell development,

110 he erythropoietic factors erythropoietin and stem cell factor is preserved in CCBE1 null embryos, but

111 ore, addition of fibroblast growth factor or stem cell factor is unnecessary using 2i-LIF.

112 T activation, through binding of its ligand, stem cell factor, is crucial for normal mast cell growth

113 e transmembrane tyrosine kinase receptor for stem cell factor, is required for melanocyte and mast ce

114 th factor, platelet-derived growth factor B, stem cell factor (kit ligand), stromal-derived factor 1,

115 Kit receptor tyrosine kinase expression and stem cell factor/Kit signaling, while preventing respons

116 on MAPK signaling or on upregulation of the stem cell factor Klf4, whereas Pax6 upregulation was sig

117 nserved domains with the induced pluripotent stem cell factor Lin28 in mammals.

118 sis by activating NF-kappaB and inducing the stem cell factor Lin28B.

119 ession and in directly interacting with this stem cell factor, linking MUC1-C with function of the PR

120 This process required membrane-localized stem cell factor (m-SCF) in megakaryocytes, which was re

121 atus: granulocyte colony-stimulating factor, stem cell factor, monokine induced by interferon-gamma (

122 iously that c-kit ligation by membrane-bound stem cell factor (mSCF) boosts IL-6 production in dendri

123 downstream target genes including well-known stem cell factors Nanog and Oct 3/4.

124 /Tai-dependent genes, including the germline stem cell factors nanos and piwi.

125 d up-regulation of stem cell markers (Bmi-1, stem cell factor, Notch-1, Nanog, nestin, ABCG2, and Oct

126 ved in invasion such as MMP9, PAI-1, and the stem cell factor OCT-3/4.

127 d on AhR and its ability to downregulate the stem cell factor Oct4.

128 f miR-34a and miR-145, which in turn repress stem cell factors OCT4, KLF4, LIN28A, and SOX2 and preve

129 C1s upregulates expression of the Kit ligand stem cell factor on these cells.

130 hosphorylation in mast cells stimulated with stem cell factor or interleukin-3, in serum-stimulated f

131 increased migratory behavior in response to stem cell factor or interleukin-8, which was associated

132 lacked mast cells through defects in either stem cell factor or its receptor, Kit.

133 We found a regenerative response because of stem cell factor overexpression characterized by an enha

134 .03); and decreased oncostatin M (P = 0.04), stem cell factor (P = 0.05), and stromal cell-derived fa

135 ween responders and non-responders including stem cell factor, platelet-derived growth factor, and in

136 ), the closest Xenopus homologs of mammalian stem cell factor Pou5f1 (Oct4).

137 nduced at least in part through upregulating stem cell factor production.

138 the activation of KIT following ligation by stem cell factor promotes a diversity of mast cell respo

139 Mechanistically, DAB2IP is able to suppress stem cell factor receptor (c-kit or CD117) gene expressi

140 Agents targeting stem cell factor receptor (C-KIT), platelet-derived grow

141 nal stromal tumors (GISTs) are prototypes of stem cell factor receptor (c-KIT)-driven cancer.

142 r binding protein-3 (IGFBP3), could modulate stem cell factor receptor (c-kit+), stem cell antigen-1

143 of Cajal (ICC) and often contain activating stem cell factor receptor (Kit) or platelet-derived grow

144 R), platelet-derived growth factor receptor, stem cell factor receptor (KIT), and colony-stimulating

145 s the Abelson (Abl), Arg (abl-related gene), stem cell factor receptor (Kit), and platelet-derived gr

146 o-B cells, particularly those expressing the stem cell factor receptor c-Kit, readily underwent apopt

147 GIST) patients who do not express the mutant stem cell factor receptor c-kit.

148 These were positive for the stem cell factor receptor c-kit.

149 (CSC) markers, including high levels of the stem cell factor receptor c-Kit.

150 ulation of the hyaluronate receptor CD44 and stem cell factor receptor CD117 (c-kit), a tyrosine kina

151 ess the hyaluronan receptor CD44, as well as stem cell factor receptor CD117 (c-kit).

152 ffinity receptor for IgE [FcepsilonRI]), the stem cell factor receptor KIT, the IL-4 system, and both

153 Here we identify CD117 (c-kit, stem cell factor receptor) as a new marker of a rare adu

154 The expression of stem cell factor receptor, c-Kit, was low basally in car

155 tor tyrosine kinase c-Kit, also known as the stem cell factor receptor, plays a key role in several d

156 of the related receptor tyrosine kinase KIT/stem cell factor receptor.

157 as platelet-derived growth factor receptors, stem-cell factor receptor, glial cell line-derived neuro

158 platelet-derived growth factor receptor, and stem-cell factor receptor.

159 A and protein for soluble and membrane-bound stem cell factor, releasing soluble stem cell factor int

160 Kit receptor tyrosine kinase and its ligand, stem cell factor, respectively.

161 Poorer STAT5 inducers in culture (IL-4 or stem cell factor) result in less IL-13 production on IL-

162 The increased expression of stem cell factor resulted in Kit-mediated proliferative

163 cent young CSCs can be stimulated in situ by stem cell factor reversing the aging myopathy.

164 Here we examine the role of stem cell factor (SCF or Kit ligand) on the early- to mi

165 We have created a stable stem cell factor (SCF) -dependent human MC line, ROSA(KI

166 Stem cell factor (SCF) acts in synergy with antigen to e

167 cord blood-derived progenitors cultured with stem cell factor (SCF) alone express intragranular trypt

168 hage colony-stimulating factor (GM-CSF), and stem cell factor (SCF) also stimulated Nbs1 expression.

169 is identified a subset of secreted proteins (stem cell factor (SCF) and CCL5) induced by ErbB2 expres

170 ed CD34(+) cells cultured in the presence of stem cell factor (SCF) and FMS-like tyrosine kinase 3 li

171 he therapeutic effects of the combination of stem cell factor (SCF) and granulocyte-colony stimulatin

172 serial passage in liquid culture containing stem cell factor (SCF) and interleukin-3 (IL-3), produce

173 oduce mast cells when stimulated in vitro by stem cell factor (SCF) and interleukin-3 (IL-3).

174 Although stem cell factor (SCF) and its receptor c-kit are consti

175 progenitors are generally assumed to require stem cell factor (SCF) and KIT signaling during differen

176 but these effects were largely abolished by stem cell factor (SCF) and maximal suppression required

177 GF-I)-dependent production of membrane-bound stem cell factor (SCF) and may involve regeneration from

178 Despite their opposite effects on growth, stem cell factor (SCF) and transforming growth factor be

179 locyte colony-stimulating factor (G-CSF) and stem cell factor (SCF) are potential new therapies to am

180 of secretion upon c-jun deletion, identified stem cell factor (SCF) as a c-Jun target gene.

181 Surprisingly, stem cell factor (SCF) as the MC-supportive mediator par

182 Stem cell factor (SCF) binds and activates the receptor

183 Stem cell factor (SCF) binds to and activates the KIT re

184 ed in response to CCL2 when cultured in IL-3+stem cell factor (SCF) but not when cultured in IL-3 alo

185 Expression of stem cell factor (SCF) by these cells is necessary for t

186 Rb), bone morphogenic protein 4 (BMP-4), and stem cell factor (SCF) constituted a common cytokine sig

187 locyte colony-stimulating factor (G-CSF) and stem cell factor (SCF) could promote myocardial regenera

188 KIT K509I progenitors cultured in stem cell factor (SCF) demonstrated a 10-fold expansion

189 locyte-colony stimulating factor (G-CSF) and stem cell factor (SCF) in a humanized murine model of Fr

190 In the present studies the role of stem cell factor (SCF) in mediating eosinophil and fibro

191 Stem Cell Factor (SCF) initiates its multiple cellular r

192 Stem cell factor (SCF) is a cytokine important for the s

193 Stem cell factor (SCF) is a growth factor that acts thro

194 Stem cell factor (SCF) is a growth factor that is involv

195 While stem cell factor (SCF) is abundant in the CNS and is che

196 The receptor for stem cell factor (SCF) is expressed on mast cells and he

197 ies local neutralization of allergen-induced stem cell factor (SCF) leads to decreased production of

198 We demonstrate that stem cell factor (SCF) mRNA and protein are highly induc

199 hage colony-stimulating factor (GM-CSF), and stem cell factor (SCF) on the experimental genesis of a

200 e effects were reversed by neutralization of stem cell factor (SCF) or cell adhesion molecule 1 (CADM

201 est synergistic proliferation in response to stem cell factor (SCF) plus GM-CSF.

202 Stem cell factor (SCF) promotes synergistic cellular pro

203 ural analyses of the extracellular region of stem cell factor (SCF) receptor (also designated KIT) in

204 Both populations contain similar levels of stem cell factor (SCF) receptor (c-Kit) but only the CD3

205 xpressed at high levels in MCC tumors is the stem cell factor (SCF) receptor tyrosine kinase, c-Kit.

206 Stem cell factor (SCF) regulates MC development and viab

207 Neutralization of stem cell factor (SCF) secreted by leukemic cells inhibi

208 Most murine gastric ICC depend on stem cell factor (SCF) signaling but can also be maintai

209 tential repressor of gamma-globin gene after stem cell factor (SCF) stimulation in cultured human adu

210 a response that is potentiated by binding of stem cell factor (SCF) to its receptor Kit.

211 gineered to express membrane-bound FLT3L and stem cell factor (SCF) together with CXCL12 induce the s

212 Stem cell factor (SCF) was secreted by differentiated tu

213 brane-bound tyrosine kinase and receptor for stem cell factor (SCF) with a crucial role in hematopoie

214 MCs was then correlated with skin levels of stem cell factor (SCF), a critical MC differentiation fa

215 Although stem cell factor (SCF), a cytokine, is known to be impor

216 Stem cell factor (SCF), a key factor in the propagation

217 Stem cell factor (SCF), a ligand of the c-kit receptor,

218 cursor cells resulted in potent induction of stem cell factor (SCF), an important pro-angiogenic fact

219 ice after stimulation with the c-Kit ligand, stem cell factor (SCF), an important regulator of mast c

220 nt, and are exposed to interleukin-6 (IL-6), stem cell factor (SCF), and chemokines such as CXCL12 (O

221 K(4) (palmitoyl-3-cysteine-serine-lysine-4), stem cell factor (SCF), and cross-linked IgE, respective

222 or CML CD34+ cells supplemented with G-CSF, stem cell factor (SCF), and granulocyte macrophage-colon

223 e myeloid-activating factors erythropoietin, stem cell factor (SCF), and hepatocyte growth factor (HG

224 ed negatively by the mast cell growth factor stem cell factor (SCF), and its expression was not detec

225 erived factor-1 (SDF-1), its receptor CXCR4, stem cell factor (SCF), and its receptor c-Kit on sectio

226 cultures and the addition of thrombopoietin, stem cell factor (SCF), and macrophage colony stimulatin

227 show that activation of c-Kit by its ligand, stem cell factor (SCF), cooperates with alpha4 integrin

228 Stem cell factor (SCF), erythropoietin (Epo), and GATA-1

229 rogenitors with interleukin 7 (IL-7), IL-15, stem cell factor (SCF), FLT-3L, and murine fetal liver c

230 Treatment with stem cell factor (SCF), Flt3-ligand (FL), IL-3, and GM-C

231 is activated after wild-type (WT) Kit binds stem cell factor (SCF), is constitutively active in cell

232 The KIT ligand, stem cell factor (SCF), is critical for mast cell expans

233 EGF), platelet-derived growth factor (PDGF), stem cell factor (SCF), macrophage-stimulating protein (

234 surface expression of c-Kit and its ligand, stem cell factor (SCF), on DCs.

235 ting factor (G-CSF)+Flt-3 ligand (FL), G-CSF+stem cell factor (SCF), or G-CSF alone starting 4 hours

236 Receptor tyrosine kinase Kit and its ligand, stem cell factor (SCF), play a critical role in the grow

237 Kit, the receptor for stem cell factor (SCF), plays a critical role in the pro

238 in promoting chemotaxis of mast cells toward stem cell factor (SCF), the ligand for KIT receptor.

239 Here, we show that stem cell factor (SCF), the ligand for KIT, induces the

240 or bone marrow (BM) HSCs using low levels of stem cell factor (SCF), thrombopoietin (TPO), insulin-li

241 preconditioning increases the expression of stem cell factor (SCF), which is critical for HSC engraf

242 hematopoietic repopulating cells from either stem cell factor (SCF)- and granulocyte-colony stimulati

243 his study, we provide evidence that blocking stem cell factor (SCF)-c-kit signaling is sufficient to

244 o determine the effect of these cytokines on stem cell factor (SCF)-dependent human mast cell product

245 t E2a/Pbx1 induces immortal proliferation of stem cell factor (SCF)-dependent pro-T thymocytes by a m

246 tosis in cultured human MCs, which depend on stem cell factor (SCF)-induced or constitutive KIT activ

247 The decrease in stem cell factor (SCF)-mediated survival in the GSK3beta

248 responses correlated with the inhibition of stem cell factor (SCF)-stimulated activation of extracel

249 cifically blocks binding of the c-kit ligand stem cell factor (SCF).

250 ch was largely independent of the effects of stem cell factor (SCF).

251 e that can be maintained in medium including stem cell factor (SCF).

252 PC mobilization with Flt3 ligand (Flt3L) and stem cell factor (SCF).

253 e and in complex with its activating ligand, stem cell factor (SCF).

254 largely controlled by the cytokines IL-3 and stem cell factor (SCF).

255 ctor (G-CSF), or a combination of G-CSF plus stem cell factor (SCF).

256 high transcript levels of Rars, Cxcl12, and stem cell factor (Scf).

257 tors required for HSC maintenance, including stem cell factor (SCF).

258 i-c-kit antibody, suggesting that endogenous stem cell factor (SCF)/c-kit interaction synergizes with

259 In this study, through analysis of the stem cell factor (SCF)/c-kit ligand receptor pair, we de

260 t the gamma position plus stimulation of the stem cell factor (SCF)/c-Kit pathway yielded high levels

261 The stem cell factor (SCF)/Kit system has served as a classi

262 equires the stimulation of axon outgrowth by Stem Cell Factor (SCF, also known as Steel Factor).

263 d activation are regulated, respectively, by stem cell factor (SCF; also known as Kit ligand) and by

264 Stem cell factor (SCF; also known as KITL) is a key nich

265 Among the candidate factors, stem- cell factor (SCF) is expressed by various human an

266 (caspase-8) and proliferation (IL-6, IL-15, stem cell factor [SCF]).

267 ptor [-R], AKT2, phosphorylated AKT [p-AKT], stem cell factor [SCF], and PDGF) were performed.

268 5) in response to 5 cytokine/growth factors (stem cell factor [SCF], Flt-3/Flk-2 ligand [FL], granulo

269 etic cytokines (interleukin-7 [IL-7], Flt3L, stem cell factor [SCF], ThPO, and IL-6) from bone marrow

270 d the obligate growth factor for mast cells, stem cell factor, SCF, is not induced.

271 by the actions of c-Kit ligand (also called stem cell factor; SCF) and fetal liver kinase 2 ligand (

272 ge colony-stimulating factors (GM-CSFs), and stem cell factors (SCFs) may be candidate treatments for

273 Pretreatment of mBMMCs with stem cell factor significantly down-regulated expression

274 -regulatory pathway cooperate to recruit the stem cell factor SOX2 in expanding and sustaining the ac

275 Expression of the stem cell factor SOX2 was repressed by DACH1, and SOX2 e

276 phenotype involves its ability to induce the stem cell factor SOX2.

277 f a set of genes, including most notably the stem cell factor SOX9, that promote proliferation and a

278 In line with these activities, upon stem cell factor stimulation, murine bone marrow-derived

279 st cells, and these were further enhanced by stem cell factor stimulation.

280 trastructural features and dependency on Kit/stem cell factor system.

281 ransgenic expression of human membrane-bound stem cell factor Tg(hu-mSCF)] would increase levels of h

282 Thus, Mam, like Hh, is a crucial stem cell factor that acts selectively on FSCs in the ov

283 Cdx2 competes with Oct4, a stem cell factor that determines commitment to the embry

284 Cdx2, a stem cell factor that determines commitment to the extra

285 e promoters of Sox2 and Pou5f1, two critical stem cell factors that are required for the maintenance

286 rom Lgr5(+) stem cells, which expressed Kitl/stem cell factor, the ligand for cKit.

287 lation with a mixture containing IL-3, IL-6, stem cell factor, thrombopoietin, and Flt3 ligand induce

288 , and urticaria, is used in conjunction with stem cell factor to generate CD34(+) cell-derived primar

289 s not known if BMI1 may also act as a cancer stem cell factor to promote cancer development.

290 tion as receptors of the R-spondin family of stem cell factors to potentiate Wnt/beta-catenin signali

291 mma chain (gammac(-/-)) and carrying a human stem cell factor transgene were engrafted with human hem

292 c-endothelial signaling, including neuritin, stem cell factor, vascular endothelial growth factor (VE

293 ro culture of bone marrow cells in IL-3 plus stem cell factor, we found that the addition of IFN-gamm

294 Degranulation by codeine was attenuated by stem cell factor, whereas the opposite was found for Fce

295 Cholangiocytes secrete stem cell factor, which functions via the MC growth fact

296 hage colony-stimulating factor (GM-CSF) plus stem cell factor, which was partially blocked by Survivi

297 hwann cells or ST88-14 cells stimulated with stem cell factor, whose receptor is also overexpressed i

298 HuMCs were cultured in stem cell factor with or without IL-6.

299 viable mast cells after culture in IL-3 plus stem cell factor, with profound apoptosis occurring as t

300 a group of three proteins (Apo AI, IL-12 and stem cell factor) yielded accuracy of 81.3%, sensitivity