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2 r cells, and primary and induced pluripotent stem cell-derived(6) hematopoietic stem progenitor cells
6 nd single-cell RNA-seq using human embryonic stem cell-derived and embryonic/fetal heart-derived card
7 phB1-ephrin-B1 pathway is disrupted in human stem cell derived astrocyte and mouse models of amyotrop
8 ly showed that maturation of human and mouse stem cell-derived astrocytes - including functional glut
9 t means for expansion of functionally mature stem cell-derived astrocytes for preclinical investigati
11 ns induced AHN deficits but increased neural stem cell-derived astrogliosis, associating with a downr
12 osphoproteomic survey of induced pluripotent stem cell-derived AT2s (iAT2s) infected with SARS-CoV-2
13 with SARS-CoV-2 by using induced pluripotent stem cell-derived AT2s that have been adapted to air-liq
14 mbrane fraction from MYL4-/- human embryonic stem cell derived atrial cells demonstrated increased ph
15 eplacement therapies (such as human islet or stem cell-derived beta cell transplantation) without imm
16 by inactivating key immunogenic epitopes of stem cell-derived beta cells intended for transplantatio
19 on protocol for generating human pluripotent stem-cell-derived beta (SC-beta) cells with improved in
20 ne cell clustering permits the generation of stem-cell-derived beta cells that resemble their endogen
21 migration, and in human induced pluripotent stem cell-derived bipolar mature neurons rotatin localiz
25 ells to generate a human-induced pluripotent stem cell-derived cardiac muscle patch (hCMP), which was
26 ation conducted in human induced pluripotent stem cell-derived cardiac myocytes (hiPSC-CM) demonstrat
27 Expression) and in human-induced pluripotent stem cell-derived cardiac myocytes deficient in SCN5A.
30 rthermore, canonical Wnt activation in human stem cell-derived cardiac progenitors produces functiona
31 tient-derived and isogenic human-pluripotent-stem-cell-derived cardio-myocytes that were genome-edite
32 extracellular potential of human pluripotent stem cell derived cardiomyocyte cells (hPSCs-CMs) for se
33 a patient-derived human induced pluripotent stem cell-derived cardiomyocyte (hiPSC-CM) CACNA1C-p.R51
34 recent advances in human induced pluripotent stem cell-derived cardiomyocyte (hiPSC-CM) technology an
35 and lead to better maturation of pluripotent stem cell-derived cardiomyocyte and novel therapeutic st
37 phenotype in human CPVT induced pluripotent stem cell-derived cardiomyocyte models with different pa
38 due to the maturation defects in pluripotent stem cell-derived cardiomyocyte, its antagonistic effect
39 ature phenotype of human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) is a major
41 7C(+/-) mutants in human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) using CRISP
43 itro experiments showed that human embryonic stem cell-derived cardiomyocytes (hESC-CMs) contain noda
45 trol subjects, and human induced pluripotent stem cell-derived cardiomyocytes (hiPS-CMs), and to char
47 Application of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) as tissue t
49 ling modulators to human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) in vitro ca
51 drug effects with human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) provide new
52 mation analyses in human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) with a hapl
53 K293) cells and in human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), and we des
54 beat amplitude in human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), but D-ala,
55 cardiomyocytes and human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), but potent
57 uman cardiomyocytes, using human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) as the targe
58 ng cardioprotective drugs, human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have been pr
61 previously reported that induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) from patient
62 re presentation of human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) is currently
68 primary limitation in the use of pluripotent stem cell-derived cardiomyocytes (PSC-CMs) for both pati
71 crosstalk between human induced pluripotent stem cell-derived cardiomyocytes and CFs via the atrial/
72 roposed therapy on human induced pluripotent stem cell-derived cardiomyocytes and different pathogeni
73 e EHM from embryonic and induced pluripotent stem cell-derived cardiomyocytes and fibroblasts with or
74 ies in vitro using human induced pluripotent stem cell-derived cardiomyocytes and various in vivo mod
76 ercially available human induced pluripotent stem cell-derived cardiomyocytes are a powerful model fo
77 tal mouse cardiomyocytes and human embryonic stem cell-derived cardiomyocytes are considerably enhanc
78 he use of isogenic human induced pluripotent stem cell-derived cardiomyocytes as a physiologically re
79 The emergence of human induced pluripotent stem cell-derived cardiomyocytes as an in vitro research
80 ing evidence suggests that human pluripotent stem cell-derived cardiomyocytes can affect "heart regen
83 ctional studies on human induced pluripotent stem cell-derived cardiomyocytes demonstrated that the a
86 generate and highly purify human pluripotent stem cell-derived cardiomyocytes displaying physiologica
87 To reveal the disease etiology, we generated stem cell-derived cardiomyocytes from HADHA-deficient hi
88 esis in patient-specific induced pluripotent stem cell-derived cardiomyocytes from NS patients carryi
89 was upregulated in human-induced pluripotent stem cell-derived cardiomyocytes from patients with doxo
90 and epigenomic data from induced pluripotent stem cell-derived cardiomyocytes from seven related indi
91 r, to date, electrophysiological analyses of stem cell-derived cardiomyocytes has largely been limite
93 ological maturation of the human pluripotent stem cell-derived cardiomyocytes in our system recapitul
94 cardiomyocytes and human induced pluripotent stem cell-derived cardiomyocytes in vitro and in vivo in
100 murine hearts and human induced pluripotent stem cell-derived cardiomyocytes provided histologic and
102 cing structural and functional maturation of stem cell-derived cardiomyocytes remains a key challenge
103 mitations of using human induced pluripotent stem cell-derived cardiomyocytes to represent clinical f
104 sodium channels in human induced pluripotent stem cell-derived cardiomyocytes using a high throughput
105 d a functional rescue in induced pluripotent stem cell-derived cardiomyocytes with D130G-CALM2, as sh
106 isolated cardiomyocytes and human embryonic stem cell-derived cardiomyocytes, and functional consequ
108 pe 2 (LQTS2) using human induced pluripotent stem cell-derived cardiomyocytes, KCNQ1 antibodies rever
109 proximately 50 000 human-induced pluripotent stem cell-derived cardiomyocytes, smooth muscle cells, a
110 ith epigenomic data from induced pluripotent stem cell-derived cardiomyocytes, we prioritized candida
119 such as isolated adult and human pluripotent stem cell-derived cardiomyocytes; (2) 2-dimensional in v
120 ayers or small clusters of human pluripotent stem cell-derived cardiomyocytes; (3) 3-dimensional mult
123 TNNT2:p.R286H iPSC-CMs (induced pluripotent stem cells derived cardiomyocytes) show hypercontractili
126 CF-7, MDA-231, and human-induced pluripotent stem-cell-derived cardiomyocytes; hiPSC-CMs) at ~kHz wit
127 mentary studies in human induced pluripotent stem cell derived-cardiomyocytes reveal Cx43 gap junctio
129 en seen as one of the first applications for stem cell-derived cells because of the loss of only a si
131 g and future therapies using bone-marrow- or stem-cell-derived cells for the treatment of neurologica
133 novations that permit generating pluripotent stem cell-derived cerebral organoids from chimpanzee.
134 fferentiation and followed the maturation of stem cell-derived clones using sparse lineage tracing in
135 hen knocked out in human induced pluripotent stem cell derived CMs, these cells exhibit reduced contr
138 ular myocytes, and human induced pluripotent stem cell-derived CMs, decreasing expression of hypertro
139 transcriptome atlas to benchmark pluripotent stem cell-derived cone photoreceptors and an adult Mulle
141 fically, using human neurons (male embryonic stem cell-derived) cultured in the absence of glia to ex
143 een mouse embryonic stem cells and embryonic stem cell-derived definitive endoderm cells, screening 7
144 for the first time that induced pluripotent stem cell-derived dendritic cells (iPS-DCs) with biallel
146 regation and toxicity in induced pluripotent stem cell-derived dopaminergic cultures treated with PD
147 al program in dopamine neurons both in human stem cell-derived dopaminergic neurons and in mice.
148 l of DNA methylation, in induced pluripotent stem cell-derived dopaminergic neurons from patients wit
153 vascular constructs, wherein human embryonic stem cell-derived endothelial cells (hESC-ECs) are seede
155 e, we used comparison of induced pluripotent stem cell-derived endothelial cells (iPSC-ECs) from thre
156 a of stem cell research, induced pluripotent stem cell-derived endothelial cells (iPSC-ECs) have emer
157 our study indicates that induced pluripotent stem cell-derived endothelial cells are useful surrogate
159 e pulmonary arterial and induced pluripotent stem cell-derived endothelial cells from patients with i
160 scular meshes from human induced pluripotent stem cell-derived endothelial cells, opening a way to en
163 fibroblasts, demonstrating a direct role of stem cell-derived exosomes on mouse endothelium at the c
164 e tested the hypothesis that human perinatal stem cell derived extracellular matrix (ECM) promotes hi
167 onstrate that endogenous expression of E4 by stem-cell-derived forebrain excitatory neurons predispos
168 n endocrine-active human-induced pluripotent stem cell-derived foregut epithelial cells and hypothala
169 interneurons (cINs) from induced pluripotent stem cells derived from 14 healthy controls and 14 subje
171 ells differentiated from induced pluripotent stem cells derived from an affected individual showed re
172 Therefore, here we tested the ability of the stem cells derived from bone marrow (BMSC), dental pulp
174 cent in situ hybridization (smFISH) on mouse stem cells derived from haematopoietic tissue to measure
175 arly and functionally similar to trophoblast stem cells derived from human blastocysts or first-trime
176 ll characterized and compared in mesenchymal stem cells derived from human dental pulp (DP-MSCs) and
177 of human bone marrow stem cells (BMSC) with stem cells derived from human dental pulp (DPSC), apical
178 AIP was also tested on induced pluripotent stem cells derived from patients with CPVT with differen
180 This enabled us to discover that neural stem cells, derived from the murine spinal cord and orga
181 r results demonstrate that human pluripotent stem cell-derived glomeruli can develop an appropriate b
183 we characterize human and mouse pluripotent stem cell-derived gray and white matter astrocyte subtyp
185 rimary human hepatocytes (PHHs), pluripotent stem cell-derived hepatocyte-like cells (HLCs), and hepa
186 larly discuss the importance of benchmarking stem cell-derived hepatocyte-like cells to their termina
187 ampus of AD patients, in induced pluripotent stem cell-derived human AD neurons, and in animal AD mod
188 -chip BBB model lined by induced pluripotent stem cell-derived human brain microvascular endothelium
189 ul ante hoc deliberations on the prospect of stem cell-derived human gametes with an eye toward minim
191 ved either endobronchial induced pluripotent stem cell-derived human MSCs (hMSCs) (n = 7) or cell-fre
194 ate that the epithelium of human pluripotent stem-cell-derived human intestinal organoids is globally
204 d subsequent maturation of human pluripotent stem cell-derived kidney organoids after renal subcapsul
206 nction in the transplanted human pluripotent stem cell-derived kidney tissue 1, 2, and 3 weeks after
207 eliability of the model and the capacity for stem cell-derived kidney tissue to recapitulate both nor
208 well as the contractile development of human stem cell-derived laminar cardiac tissues over four week
209 primary mouse and human induced pluripotent stem cell-derived lung epithelial cells to model early-s
211 tically engineered human induced pluripotent stem cell-derived microglia-like cells to show that TREM
212 Taken together, our study illustrates how stem cell derived models can be used to uncover and resc
215 Yet, timely transfusion of haematopoietic-stem-cell-derived monocytic cells in newborn mice is suf
217 cle progenitors mixed with human pluripotent stem cell-derived motor neurons self-organize to form fu
218 sected motor neurons, or induced pluripotent stem cell-derived motor neurons specifically from amyotr
222 ved from Megf10-/- mice, induced pluripotent stem cell-derived myoblasts from MEGF10 myopathy patient
223 old, skeletal muscle tissue, and optogenetic stem cell-derived neural cluster containing motor neuron
224 NIR-based biosensing of neurotransmitters in stem cell-derived neural interfaces present a unique too
226 citation of transplanted induced pluripotent stem cell-derived neural progenitor cells (iPS-NPCs) cou
229 duced CDKL5-mutant human induced pluripotent stem cell-derived neural progenitors, which were subsequ
231 rigger glial competency of human pluripotent stem cell-derived neural stem cells within 5 days and to
232 Joseph disease patients' induced pluripotent stem cells-derived neural stem cells incubated with ibup
234 ata, and our own mouse hippocampal and human stem cell-derived neuron PAC-seq data-strongly supports
235 frontal cortex (PFC) and induced pluripotent stem cell-derived neuronal cultures from patients with s
236 at tau overexpression in induced pluripotent stem cell-derived neurons altered chromatin structure an
237 ted the utility of human induced pluripotent stem cell-derived neurons and astrocytes as tools to sys
238 ed manipulation in human induced pluripotent stem cell-derived neurons and RNAi-based knockdown in Dr
239 vated following infection of human embryonic stem cell-derived neurons and that this activation of JN
240 enomic analyses on human induced pluripotent stem cell-derived neurons at 22, 50 and 78 days (D) post
241 ry after stroke in animal models but whether stem cell-derived neurons become functionally integrated
242 MN2 accumulated in human induced pluripotent stem cell-derived neurons depleted of TDP-43, but not in
243 ocalization was altered in primary and human stem cell-derived neurons expressing ALS-linked FUS vari
245 hippocampal neurons and induced pluripotent stem cell-derived neurons from a patient carrying a null
246 into excitatory neurons, induced pluripotent stem cell-derived neurons from all three patients displa
247 ng pathophysiology using induced pluripotent stem cell-derived neurons from AS patients and unaffecte
248 kin or SLP-2, as well as induced pluripotent stem cell-derived neurons from Parkin mutation carriers,
249 g the landscape of open chromatin regions in stem cell-derived neurons helps functional interpretatio
250 udy using embryonic stem cells and embryonic stem cell-derived neurons indicated that Nf1 RasGAP acti
251 we show that the use of induced pluripotent stem cell-derived neurons of monozygotic twins from pair
252 Overexpression of NLGN4 in human embryonic stem cell-derived neurons resulted in an increase in exc
253 s also apparent in human induced pluripotent stem cell-derived neurons, a disease-relevant cell type.
254 xpression profiling of human neuroepithelial stem cell-derived neurons, stimulated with normal consum
260 utilizing isogenic human-induced pluripotent stem cells-derived neurons from PD patients with autosom
262 we show that endogenous expression of E4 in stem-cell-derived neurons predisposes them to injury and
265 cal NK cells, umbilical cord blood NK cells, stem cell-derived NK cells, NK cell lines, adaptive NK c
266 hange in excitability in induced pluripotent stem cell derived nociceptors with the C110R mutation an
267 of chronic HIF1a accumulation in pluripotent-stem-cell-derived oligodendrocyte progenitors (OPCs), we
270 lucloxacillin and in primary hepatocytes and stem cell-derived organoids from multiple donors treated
274 xacerbated cell death in induced pluripotent stem cell-derived primary human neurons under oxidative
275 zed a protocol to generate human pluripotent stem cell-derived Purkinje cells (hPSC-PCs) that formed
280 ted using clinical-grade induced pluripotent stem cell-derived retinal pigment epithelial cells (iPSC
286 egenerative medicine approaches that utilise stem cell-derived RPE cells to treat conditions such as
288 omatin using sequencing on human pluripotent stem cell-derived SAN-like pacemaker cells and ventricle
289 ell differentiated, while hair follicle (HF) stem cell-derived SCCs frequently exhibit EMT, efficient
290 Recent studies have demonstrated an array of stem cell-derived, self-organizing miniature organs, ter
291 onditions by which human induced pluripotent stem cell-derived sensory neurons can be cultured with r
292 We found that human induced pluripotent stem cell-derived sensory neurons expressed the receptor
293 n either rodent or human induced pluripotent stem cell-derived sensory neurons in vitro potently inhi
294 eled in subject-specific induced pluripotent stem cell-derived sensory neurons in vitro; second, that
295 co-cultures using human induced pluripotent stem cell-derived sensory neurons thus provide insights
296 Dmd C3333Y animals, induced-pluripotent-stem-cell-derived skeletal muscle cells from patients wi
299 te if transplantation of induced pluripotent stem cell derived TM like cells (iPSC-TM) restores TM ce