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1 echanically and chemically stable and can be sterilized.
2 vidence that vaccine-induced immunity is not sterilizing.
5 000 units (10 ng) of enzyme is sufficient to sterilize a culture of approximately 10(7) group A strep
6 encies that might have led to the failure to sterilize a specific case containing a partial lot of th
7 nfection was established, recapitulating the sterilizing activities of human latent tuberculosis infe
8 ity, low cytotoxicity, potent broad-spectrum sterilizing activity against a panel of gram-positive an
10 hroughput screen have potent, broad-spectrum sterilizing activity against Gram-positive and Gram-nega
13 sing levels of incomplete neutralization the sterilizing activity diminishes.IMPORTANCE Multiple anti
15 To test this hypothesis we evaluated the sterilizing activity of improved once-weekly rifapentine
17 This model may be useful for screening the sterilizing activity of novel anti-tuberculosis drugs, a
19 The pharmacological basis for the in vivo sterilizing activity of the drug has remained obscure an
22 s are known to copulate with and effectively sterilize Ae. aegypti females by causing them to reject
23 hough her B anthracis bacteremia was rapidly sterilized after initiation of antibiotic therapy, viabl
24 In addition, the potential use of SGHVs as sterilizing agents for house fly control and the deleter
25 ng the inhibitory effects of IP-10 and other sterilizing agents for post-PCR sterilization of amplico
26 t drug, S the population susceptible only to sterilizing agents, t the day of sputum collection as re
27 ntravitreous injection of lysostaphin (0.1%) sterilized all eyes of immunized and nonimmune rabbits w
28 erapy (4 -9 hours postinfection) lysostaphin sterilized all MRSA 301-infected corneas, whereas untrea
30 0, the pharmacy began compounding and filter-sterilizing amino acid solution for adult PN using nonst
34 This semi-opaque polymer that can be easily sterilized and recycled provides low background noise fo
39 des studied, including non-pore-formers, had sterilizing antimicrobial activity against at least some
44 Daily volumes were 30 to 40 ml of filter-sterilized, bicarbonate-buffered solutions that containe
45 a growth medium of prereduced, anaerobically sterilized brain-heart infusion with 2% horse serum.
46 ngs indicate that residual DNA can remain in sterilized bronchoscopes and can be a source of false-po
49 by a modified solvent evaporation technique, sterilized by 25 kGy of gamma-irradiation, and character
51 restores oocyte production in wild-type mice sterilized by chemotherapy, as well as in ataxia telangi
52 ) Filipino ethnic food chicken breast Adobo, sterilized by exposure to high-dose gamma rays (25 kGy)
53 plemented with synthetic uraninite (UO2(s)), sterilized by gamma-irradiation, and then subjected to a
55 uture sterility as a result of the need of a sterilizing cancer therapy might avoid this fate by engr
57 culture conversion at 2 months indicates the sterilizing capacity and potential of regimens to shorte
59 atment reagent (SR) was also studied for its sterilizing capacity, stability, and effect on assay sen
64 compound known to drive the Fenton reaction, sterilizes cultures of drug-susceptible and drug-resista
66 ndard to determine when antibiotics induce a sterilizing cure has confounded the development of new a
68 r cells, which raises the possibility that a sterilizing cure of HIV-1 infection, which has previousl
69 when designing therapies for a functional or sterilizing cure to HIV.IMPORTANCE The latent viral rese
70 The consensus reached was that a complete sterilizing cure, i.e., viral eradication from the host,
71 itself or by the patient's immune system, a "sterilizing cure." Although administered within the cont
73 a-particle emitters, and their potential for sterilizing disseminated tumor cells (DTCs), it is criti
74 -beam (E-beam) irradiation equivalent to the sterilizing dosage used by the U.S. Postal Service and t
76 e useful predictors of rapid bactericidal or sterilizing drug activity, and would expedite the licens
77 apy in that they are more susceptible to the sterilizing drug, rifampin, than to the bactericidal dru
79 y containment facility, we show that the key sterilizing drugs rifampicin and pyrazinamide efficientl
81 tial macrofilaricidal and a modest permanent sterilizing effect after 4 or more consecutive treatment
84 drug exposures, to identify bactericidal and sterilizing effect rates, and to identify exposures asso
85 llow fiber studies for both bactericidal and sterilizing effect, with inoculum spiked with 0.5% rifam
87 protects Drosophila neotestacea against the sterilizing effects of a parasitic nematode, both in the
88 Our quantification of macrofilaricidal and sterilizing effects of ivermectin should be incorporated
89 tion between these species in nature and the sterilizing effects of male accessory gland products asy
92 HIV-1 and other viruses), antibacterial self-sterilizing fabrics (which kill antibiotic-resistant bac
93 OdsH from D. mauritiana (OdsHmau) acts as a sterilizing factor by associating with the heterochromat
94 e E. coli in MacConkey agar was inhibited by sterilized feather meal (p = 0.01) and by the antimicrob
96 le Ae. albopictus can competitively mate and sterilize females at a level adequate to suppress a fiel
98 Only one of the containers with an adapted sterilizing filter (2.1%) became contaminated with Staph
103 echnique (ISDT)-would eliminate incompletely sterilized fragments of skin from the culture specimen a
105 . strain Wigar10 was isolated from a surface-sterilized garlic bulb (Allium sativum var. Purple Strip
108 pathogen's ability to overcome a potentially sterilizing immune response in the vector mosquito.
112 , the results suggest protective rather than sterilizing immunity after recovery from hepatitis C.
115 s infection through a natural route provided sterilizing immunity against both homologous and heterol
117 targeted deletion at the BAD1 locus confers sterilizing immunity against experimental lethal pulmona
120 ination with inactivated virus, resulting in sterilizing immunity against homologous challenge and fu
122 programmed cell death mechanisms, directing sterilizing immunity against intracellular bacterial pat
124 N1 (rPIV5-H5) from the H5N1 subtype provided sterilizing immunity against lethal doses of HPAI H5N1 i
125 fluenza (HPAI) virus H5N1 (PIV5-H5) provides sterilizing immunity against lethal doses of HPAI H5N1 i
126 dose of the B/Bris att candidate stimulated sterilizing immunity against lethal homologous challenge
127 T cells in the blood that predicts long-term sterilizing immunity against liver-stage infection.
129 nduced antibodies are protective and provide sterilizing immunity against P. falciparum infection whe
130 proaches do not provide efficient long-term, sterilizing immunity against Plasmodium infections in hu
133 when delivered in Montanide ISA 51, induced sterilizing immunity against sporozoite challenge in C57
134 ate and adaptive responses were required for sterilizing immunity against the modified strain, and co
135 common sites of infection, can achieve near-sterilizing immunity against viral infections by reversi
136 gn and passive antibody therapies to provide sterilizing immunity and control blood-stage parasites.
137 t to develop as a vaccine: it does not offer sterilizing immunity and its mode of action relies on Fc
139 inees showed significant (P = 0.03) apparent sterilizing immunity and no detectable viral loads.
140 TRAP130-138-specific CD8(+) T cells provide sterilizing immunity and reduce liver parasite burden af
141 uction, classical macrophage activation, and sterilizing immunity are elicited in response to infecti
142 IV(SF162P3), showing that PGT121 can mediate sterilizing immunity at serum concentrations that are si
143 question for vaccine development is whether sterilizing immunity at the level of the oviduct is esse
145 shed early in the infection not only prevent sterilizing immunity but also represent a major obstacle
147 TB-like diseases in humans and animals elude sterilizing immunity by residing within an intracellular
149 2 weeks, 10 of 12 monkeys exhibited apparent sterilizing immunity despite a mismatch of Env sequences
150 obulin G purified from this animal conferred sterilizing immunity following passive transfer to macaq
151 by vaccination that fall short of providing sterilizing immunity impact disease progression or influ
153 antiviral neutralizing IgG, known to confer sterilizing immunity in pig-tailed monkeys, has been use
154 , the strongly neutralizing MAb b12 provided sterilizing immunity in seven of seven animals, b6 in ze
157 ble to provide the type of antibody-mediated sterilizing immunity induced by traditional vaccines.
159 ibuting to bacterial persistence and lack of sterilizing immunity may be the low quality of memory ce
160 s of the week 22 challenge but also with the sterilizing immunity observed in 5 of 5 SIV239Deltanef-i
162 all respiratory organs, providing completely sterilizing immunity that protected against challenge in
165 ssive transfer of anti-HIV-1 NAbs conferring sterilizing immunity to macaques has been used to determ
166 ing in malaria endemic areas fail to develop sterilizing immunity to malaria infection has led to the
168 of a tuberculosis (TB) vaccine that induces sterilizing immunity to Mycobacterium tuberculosis infec
170 ty/04 att-H1N1 vaccine candidate resulted in sterilizing immunity upon an aggressive intratracheal ch
171 However, the mechanism of protection is not sterilizing immunity via elimination of the inoculum as
174 lowing vaccination with a LAIV that provided sterilizing immunity were below the level considered pro
175 a dramatic effect on the extent of apparent sterilizing immunity when challenge occurs relatively ea
176 , compared to 12 of 12 monkeys with apparent sterilizing immunity when challenge virus was matched in
177 genome integration indicates that persistent sterilizing immunity will be needed for a successful vac
178 cially, a single dose of 10-del ZIKV induced sterilizing immunity with a saturated neutralizing antib
181 rophylaxis (PrEP), potential benefits beyond sterilizing immunity, and a discussion of future approac
182 hat vaccine-primed B cells are essential for sterilizing immunity, and the results indicate that the
183 lammation, and pathology but does not confer sterilizing immunity, as evidenced by detection of viral
184 gainst future infection but does not provide sterilizing immunity, as evidenced by HBcore- and polyme
185 ins unresolved: lymphocytes are required for sterilizing immunity, but their presence during the earl
186 ombinant vectors, although unable to provide sterilizing immunity, can control viremia and prevent di
187 fections result from evasion or avoidance of sterilizing immunity, extend the timeframe of virus tran
188 s contains bacterial spread without inducing sterilizing immunity, therefore benefitting both host an
189 f six animals showed complete protection and sterilizing immunity, while for one animal in each group
203 of a new technology into the procedure which sterilizes(inactivates) PCR amplicons, and thereby overc
204 , short-range radiation emissions capable of sterilizing individual cells with one to three traversal
206 at IEC Ifnlr1 expression is required for the sterilizing innate immune effects of IFN-lambda by exten
207 od of pest control involving mass release of sterilized insects that reduce the wild population throu
210 ion of the vessels was performed with filter-sterilized isotonic and hypertonic solutions that contai
211 VM plus ALB was no better than IVM alone for sterilizing, killing adult worms, or achieving sustained
212 VM plus ALB was no better than IVM alone for sterilizing, killing of adult worms or achieving sustain
213 n of V. cholerae into a nutrient-poor filter sterilized lake water (FSLW) microcosm promoted a shift
214 pletely restored upon addition of 3% surface sterilized leaves of P. gracilior, suggesting the implan
215 erimental models of human and mouse malaria, sterilizing liver stage immunity that blocks progression
216 tter equipped to design vaccines that elicit sterilizing, long-lasting immunity without inducing immu
218 ill eliminate burdens of manually sexing and sterilizing males, thereby reducing overall effort and i
220 veloped world often use autoclave systems to sterilize medical instruments and equipment and process
225 r thermal processing, i.e. pasteurized milk, sterilized milk, UHT fresh milk and recombined milk (UHT
229 sistant Mycobacterium tuberculosis (Mtb) and sterilizes Mtb in vitro combined with rifampicin or ison
230 We also show that all three FQs struggle to sterilize non-replicating bacteria residing in caseum.
231 is study was to evaluate a new technique for sterilizing nonlumen electrophysiology catheters that us
232 zation may provide a cost-effective means of sterilizing nonlumen electrophysiology catheters without
233 Periodontal disease was induced by placing a sterilized nylon (000) thread ligature around the cervix
235 uation in which the habitable zone was fully sterilized on Earth, at least since the termination of p
237 3-CO(2) laser in periodontal pockets did not sterilize or substantially reduce subgingival bacterial
242 from the incubations were used to inoculate sterilized parent soils to assess the microbial communit
245 s that virus choice should focus more on its sterilizing power rather than transmission efficiency.
248 RV144 "Thai" trial showing potential modest sterilizing protection by nonneutralizing antibody respo
250 While neutralizing antibodies can provide sterilizing protection from HIV infection via their vari
251 1 therapeutic regimen can provide apparently sterilizing protection from infection following a rigoro
252 dy 2G12 is of particular interest due to the sterilizing protection it provides from viral challenge
253 um levels of 2F5 IgG were more predictive of sterilizing protection than measured vaginal levels.
256 ver following a high-dose challenge and ~50% sterilizing protection with a low-dose challenge compare
258 d subjecting soil mesocosms to either filter-sterilized rain (no dispersal) or unfiltered rain (dispe
260 re both rapidly bactericidal (isoniazid) and sterilizing (rifampin and pyrazinamide), and ethambutol
262 Bouteloua gracilis seeds were planted in sterilized sand with (inoculated) and without (controls)
263 en we inoculated those soil microbiomes into sterilized soil and grew chrysanthemum as a focal plant.
268 euse of disposable syringes and inadequately sterilized syringes resulted in 39% of all injections be
269 ssociated with infection, thereby enabling a sterilizing T cell response to develop and resolve the i
270 l therapy as observed in this cohort did not sterilize testing; however, no pretreated organisms iden
271 , often residing in macrophages that neither sterilize the bacilli nor allow them to cause disease.
275 or new TB drugs that rapidly and effectively sterilize the tissues and are thus able to shorten the d
276 oviding continuous antibiotic prophylaxis to sterilize the urine and thus prevent recurrent infection
277 n antibiotic treatments that can effectively sterilize the urine, recent studies demonstrate that uro
278 mes during the first billion years, may have sterilized the Earth, and required the process to start
279 y electrogenic Cl(-) secretion, hydrates and sterilizes the crypt, thus reducing bacterial adherence.
284 cessed in one of two methods: (a) soils were sterilized then inoculated with parent soil microbes to
286 ogies that can be manufactured conveniently, sterilized to minimize contamination and enhance shelf-l
287 pment of new drug regimens that allow rapid, sterilizing treatment of tuberculosis has been limited b
288 sorbed dose distributions are inefficient in sterilizing tumors and become proportionately less effec
289 ions of 50 and 100 micrograms/ml effectively sterilized up to 10(11) amplicons, the compound was inhi
290 r both groups, the surgical instruments were sterilized using full-cycle, steam sterilization, with a
292 changes in HeLa cells incubated with filter-sterilized whole-cell lysates of reference and monkey Ca
293 The instruments for the first group were sterilized with equipment located adjacent to the operat
296 iomass of M. aeruginosa (high-pressure steam sterilized) with an additional 10 g/L of glucose as an e