ライフサイエンスコーパス: steroid hormone

1 osis that follows the administration of this steroid hormone.

2 s, with progesterone being the most abundant steroid hormone.

3 drosterone, an important naturally occurring steroid hormone.

4 enolone or estrogen, another major mammalian steroid hormone.

5 sion, differentiation, and responsiveness to steroid hormones.

6 nolone, the first 21-carbon precursor of all steroid hormones.

7 ons and understanding of brain modulation by steroid hormones.

8 -disrupting compounds such as pesticides and steroid hormones.

9 receptors to provide the full impact of all steroid hormones.

10 ine production, carbohydrate metabolism, and steroid hormones.

11 cholesterol, a key step in the generation of steroid hormones.

12 and constrained with productions of selected steroid hormones.

13 uronidated estrogen, testosterone, and other steroid hormones.

14 ysiological role in transport and balance of steroid hormones.

15 to changing photoperiod and circulating sex steroid hormones.

16 uberty approaches, and is independent of sex steroid hormones.

17 ed on measuring prenatal androgens and other steroid hormones.

18 involves gonadotrophic hormones and ovarian steroid hormones.

19 of the uterus to decidualise in response to steroid hormones.

20 sma membranes (PMs) and the precursor of all steroid hormones.

21 Estrogen receptors (ER) are activated by the steroid hormone 17beta-estradiol.

22 The current study examined whether the steroid hormone, 17beta-estradiol (E2) can exert long-la

23 is regulated by the interaction between the steroid hormone 20-hydroxy-ecdysone (20E) transferred by

24 yo to bacterial infections and find that the steroid hormone 20-hydroxyecdysone (20-HE) can regulate

25 In this study, we show that the Drosophila steroid hormone 20-hydroxyecdysone (20E) and its nuclear

26 re, we demonstrate a key requirement for the steroid hormone 20-hydroxyecdysone (20E) in the maintena

27 Here we show that the male-transferred steroid hormone 20-hydroxyecdysone (20E) is a key regula

28 c processes, principally orchestrated by the steroid hormone 20-hydroxyecdysone (20E), remains largel

29 t partially mediated by the male-synthetized steroid hormone 20-hydroxyecdysone (20E), which is packa

30 processing and slows down the release of the steroid hormone 20E from the mating plug.

31 roved our understanding of the mechanisms of steroid hormone action on bone and how physiologic, path

32 sed on a validated chemical kinetic model of steroid hormone action, is now used to identify two new

33 It is also a major site of sex steroid hormone action.

34 The steroid hormone-activated glucocorticoid receptor (GR) r

35 The glucocorticoid receptor (GR) is a steroid-hormone-activated transcription factor that modu

36 differences in the serum levels of hexoses, steroid hormones, acylcarnitines, purine, heme, bile aci

37 at constitutively produce the salt-retaining steroid hormone aldosterone and cause millions of cases

38 pharmaceuticals, personal care products, and steroid hormones, all at ng/L levels in surface and drin

39 Cholesterol is responsible for synthesis of steroid hormones and bile acids, which have been recogni

40 vidence suggests that the actions of ovarian steroid hormones and brain-derived neurotrophic factor (

41 We observed no association between steroid hormones and ER(+)/PR(+) disease.

42 d treated wastewater effluent to the load of steroid hormones and other wastewater micropollutants (W

43 , transformation, and attenuation of natural steroid hormones and phytoestrogens and estrogenic activ

44 tween high concentrations of early pregnancy steroid hormones and risk of ER(-)/PR(-) breast cancer i

45 Seven sex steroid hormones and SHBG were quantitated using gas chr

46 Seven sex steroid hormones and SHBG were quantitated using gas chr

47 ally <5%; however, rates were higher for the steroid hormones and some of the more challenging compou

48 with an increase in urinary excretion of sex steroid hormones and their metabolites in humans.

49 These results underscore the role of sex steroid hormones and their receptors in diseases that de

50 n-like growth factor-1, leptin, adiponectin, steroid hormones, and cytokines.

51 ate cancer progression is driven by androgen steroid hormones, and delayed by androgen deprivation th

52 , it is becoming increasingly clear that sex steroid hormones, and in particular the principle female

53 was to elucidate the mechanism by which the steroid hormone androgen regulates YAP1 nuclear entry an

54 ndicate that the transformation processes of steroid hormone are stereoselective in sediment and co-o

55 Steroid hormones are a large family of cholesterol deriv

56 two of the most commonly observed androgenic steroid hormones are androstenedione (AD) and testostero

57 or ionization and localized ion suppression, steroid hormones are difficult to detect.

58 Steroid hormones are essential for carbohydrate metaboli

59 Female steroid hormones are hypothesized to play a protective r

60 recombinant follicle-stimulating hormone and steroid hormones are ineffective.

61 Several endocrine factors, including sex-steroid hormones are known to influence adiponectin secr

62 s in endogenous postmenopausal levels of sex steroid hormones are not substantially related to these

63 Because steroid hormones are often conjugated to glucuronic acid

64 Steroid hormones are pivotal modulators of pathophysiolo

65 ession of endocrine related-cancers in which steroid hormones are powerful mitogenic agents.

66 Steroid hormones are produced throughout the phylogeneti

67 lts indicate that short-term treatments with steroid hormones are sufficient to alter both Lep transc

68 Circulating gonadal steroid hormones are thought to modulate a wide range of

69 Sexual transfer of this steroid hormone as part of a mating plug dramatically ch

70 duction during infusion of deuterium-labeled steroid hormones as tracers; plasma clearance of 100 mg

71 rosterone sulfate (DHEA-S), a small-molecule steroid hormone, as the target analyte.

72 dogenous and exogenous substrates, including steroid hormones, bile acids, and commonly used drugs, s

73 ber intake, which has been shown to decrease steroid hormone bioavailability (decreased blood concent

74 ssion profiles showed that genes involved in steroid hormone biosynthesis (Star, Cyp11a1, and Hsd3b1)

75 ute the dogma that TSPO is indispensable for steroid hormone biosynthesis and viability.

76 sphingolipids have been shown to control the steroid hormone biosynthesis in adrenal glands, indicati

77 Human steroid hormone biosynthesis is the result of a complex

78 hondrial membrane, the rate-limiting step in steroid hormone biosynthesis.

79 Plant steroid hormones brassinosteroids (BRs) regulate plant g

80 Plant steroid hormones, brassinosteroids (BRs), play essential

81 Plant steroid hormones, brassinosteroids (BRs), play essential

82 The plant steroid hormones, brassinosteroids (BRs), play important

83 l plasticity is linked to the actions of sex steroid hormones, but the precise mechanisms are unclear

84 Properly timed production of steroid hormones by endocrine tissues regulates juvenile

85 H4IIE-luc bioassay, effects on production of steroid hormones by use of the H295R steroidogenesis ass

86 Alkylation of a steroid hormone can be achieved.

87 actors, but it has long been recognised that steroid hormones can exert powerful modulatory effects a

88 This study demonstrates that steroid hormones can help reestablish functional neurona

89 Our data imply that steroid hormones can shift the immunological balance in

90 en that Chst10 transfers sulfates to several steroid hormones, Chst10 likely functions in widespread

91 rmone-dependent diseases predominantly alter steroid hormone concentrations (or their actions) in pla

92 Because BDNF and gonadal steroid hormones conjointly influence neuronal growth, s

93 Steroid hormones control important developmental process

94 Steroid hormones control various aspects of brain develo

95 esponsible for the final step generating the steroid hormone cortisol, which controls stress and immu

96 of neuroblast proliferation/quiescence and a steroid hormone cue that is required for temporal transc

97 e present study, a clinically used synthetic steroid hormone, danazol, was investigated for its CS pr

98 Current therapies of steroid hormone-dependent diseases predominantly alter s

99 ce, we used gonadectomy to eliminate gonadal steroid hormone-dependent expression of AVP in the BNST

100 tor complex plays a key coregulatory role in steroid hormone-dependent transcription and is chiefly t

101 The phenotype depends on sex-steroid hormones: dihydrotestosterone treatment of gonad

102 relevant circuit.SIGNIFICANCE STATEMENT Sex steroid hormones drive changes in brain circuits in all

103 nd songbirds is linked to the actions of sex steroid hormones during ontogeny but also in adulthood i

104 ed for cellular uptake of the primary insect steroid hormone ecdysone [2].

105 The steroid hormone ecdysone and its receptor (EcR) play cri

106 tion of autophagy disrupts production of the steroid hormone ecdysone at the time of pupariation not

107 In Drosophila, the steroid hormone ecdysone controls developmental transiti

108 Here, we show that the steroid hormone ecdysone controls the expression of the

109 We show that the steroid hormone ecdysone functions in Drosophila to cont

110 that in Drosophila, endocrine release of the steroid hormone ecdysone is mediated through a regulated

111 The steroid hormone ecdysone is the central regulator of ins

112 Previous research suggested that the steroid hormone ecdysone may play a role in this polyphe

113 Sequential pulses of the steroid hormone ecdysone regulate the major developmenta

114 anscription factors following a pulse of the steroid hormone ecdysone such that different times in wi

115 regulated in a cell-autonomous manner by the steroid hormone ecdysone, through changes in expression

116 The active ovaries of the fly produce the steroid hormone ecdysone, which stimulates the division

117 ogenic differentiation when treated with the steroid hormone ecdysone.

118 the larval-to-pupal molt orchestrated by the steroid hormone ecdysone.

119 and maturation through the secretion of the steroid hormone ecdysone.

120 The insect steroid hormone, ecdysteroid, coordinates growth and mat

121 ormation processes do not necessarily reduce steroid hormone ecotoxicity.

122 nfection, have been well documented, as have steroid hormone effects on the microbiome, which is know

123 ggest that dSTACs functionally mimic gonadal steroid hormones, enabling sirtuins to transduce the cog

124 suggest a transporter-mediated mechanism of steroid hormone entry into the CNS, which may provide im

125 The sex-steroid hormone estradiol (E2) enhances the psychoactive

126 The steroid hormone estrogen is important for brain function

127 under the continuous control of the ovarian steroid hormones, estrogen and progesterone.

128 lpha4 subunits, which is also a PAM site for steroid hormone estrogens such as 17beta-estradiol.

129 Free and conjugated steroid hormones (estrogens, androgens, and progesterone

130 Progesterone (P4) is a natural steroid hormone excreted by humans and animals.

131 e (LH) pulse frequency, implicating abnormal steroid hormone feedback to gonadotropin-releasing hormo

132 and estradiol in the mechanisms by which sex-steroid hormone fluctuations provoke depressive symptoms

133 explore these phenomena for endocrine-active steroid hormones, focusing on examples of conserved bioa

134 It is generally believed that steroid hormones freely diffuse through the plasma membr

135 d BR signalling network and explain how this steroid hormone functions as a master regulator of plant

136 as a representative gene to investigate how steroid hormone, genetic, and epigenetic signals are int

137 pressed glucocorticoid receptors (GRs), this steroid hormone has pleiotropic effects on many cell typ

138 Throughout the animal kingdom, steroid hormones have been implicated in the defense aga

139 ole in the regulation of systemic energy and steroid hormone homeostasis.

140 as the sulfate DHEA-S, is the most abundant steroid hormone in human blood.

141 Cortisol is an important steroid hormone in human physiology.

142 rone (DHEA) is the most abundant circulating steroid hormone in humans, produced by the adrenals, the

143 Testosterone is a key steroid hormone in the development of male reproductive

144 s glucuronidated steroid hormone to regulate steroid hormone in vivo.

145 le and the role of gonadotropins and ovarian steroid hormones in ESR36 expression.

146 tective, but mechanistically unclear role of steroid hormones in female colorectal cancer patients, o

147 sents an analytical method for evaluating 15 steroid hormones in fish tissue.

148 synthesized T rather than cortisol, secreted steroid hormones in response to dibutyryl-cAMP and 22(R)

149 and rapid non-genomic actions of circulating steroid hormones in the brain.

150 of a "window of therapeutic opportunity" for steroid hormones in the brain.

151 a new signaling pathway in the regulation of steroid hormones in the uterus, and to overcome P4 resis

152 likely functions in widespread regulation of steroid hormones in vivo.

153 esponsible for tissue resistance to multiple steroid hormones including glucocorticoids observed in a

154 nzymatic process that terminally inactivates steroid hormones, including estrogens and androgens, the

155 Maternal exposure to increased steroid hormones, including estrogens, androgens or gluc

156 The steroid hormone-induced effect on BKCa channels is a tar

157 s of non-pregnant animals, hypoxia inhibited steroid hormone-induced up-regulation of BKCa channel cu

158 We identified E93, a steroid-hormone-induced transcription factor that downre

159 ing development, cellular reprogramming, and steroid hormone induction.

160 ingle most important precursor for the world steroid hormone industry.

161 ted by psychological stress, but cortisol "a steroid hormone" is known as a potential biomarker for i

162 Cortisol, a steroid hormone, is an important biomarker for psycholog

163 serve as the major source of progesterone, a steroid hormone known to affect the replication of some

164 fate and bioavailability of progesterone, a steroid hormone known to cause endocrine-disrupting effe

165 Pregnancy, parity, and circulating steroid hormone levels are associated with risk of breas

166 method was successfully applied to determine steroid hormone levels in the breast tissue of healthy w

167 Sex steroid hormone levels were measured in 24-h urine sampl

168 -based coloration, cellular immune response, steroid hormone levels, and reproduction.

169 cleus HVC in response to seasonal changes in steroid hormone levels, and send long axonal projections

170 e a significant contributor to environmental steroid hormone loading from cattle feedyards.

171 tent anti-inflammatory and immunosuppressive steroid hormones, mainly produced by the adrenal glands.

172 Steroid hormones mediate critical lineage-specific devel

173 y for implantation is orchestrated by cyclic steroid hormone-mediated signals.

174 lopment, connecting glucose, cholesterol and steroid hormone metabolism with early embryonic cell mov

175 up of steroids with structural similarity to steroid hormones of mammals.

176 e literature evaluating the impact of female steroid hormones on cognition, and the putative mechanis

177 iving rise to the idea that the influence of steroid hormones on early fetal brain development may be

178 has been characterized, the influence of sex steroid hormones on intrinsic cerebellar network dynamic

179 MSP suggests an indirect paracrine effect of steroid hormones on stem cells via the mature neighborin

180 ntal systems employed to study the impact of steroid hormones on the genome.

181 c enzymes metabolize cholesterol, generating steroid hormones or bile acids.

182 We propose that trafficking of steroid hormones out of endocrine cells is not always th

183 ture with E-cadherin fragment expression and steroid hormone pathway activation, whereas ovarian canc

184 we identify a new HSP90 client in the plant steroid hormone pathway: the transcription factor BES1.

185 x 10(-8)), implicating genes involved in sex steroid hormone pathways (FN1, CCDC170, ESR1, SYNE1 and

186 brain development and behavior by regulating steroid hormone permeability across the BBB.

187 In this study, the distribution of steroid hormones, phytoestrogens, and estrogenic activit

188 Steroid hormones play key roles in development, growth,

189 t rather by limiting the availability of the steroid hormone precursor cholesterol in the endocrine c

190 Pregnenolone is a steroid hormone precursor that is synthesized in various

191 dition to serving as the precursor for other steroid hormones, pregnenolone exerts its own effect as

192 Steroid hormones produce adverse effects on biota as wel

193 kews lipid catabolism to enhance cholesterol/steroid hormone production and repress obesity.

194 ovide the critical second messenger to drive steroid hormone production.

195 The altered steroid hormone profile in obese men may contribute to t

196 The blubber steroid hormone profiles of 52 female humpback whales mi

197 The steroid hormone progesterone (P4) mediates many physiolo

198 The steroid hormone progesterone activates CatSper of human

199 The female steroid hormone progesterone regulates ovulation and sup

200 rine gland that synthesizes and secretes the steroid hormone, progesterone, which is vital for establ

201 xpression in response to binding its cognate steroid hormone, progesterone.

202 expression in MB neuroblasts, and extrinsic steroid hormone receptor (EcR) activation boosts E93 lev

203 ogate how DNA recognition diversified in the steroid hormone receptor (SR) family.

204 ding of hAgo2 is analogous to Hsp90-mediated steroid hormone receptor activation.

205 Genes involved in steroid hormone receptor activity and circadian rhythm w

206 aperone and target classes by assaying HSP70/steroid hormone receptor and CDC37/kinase interactions,

207 regated membrane versus nuclear actions of a steroid hormone receptor and demonstrated their in vivo

208 and progesterone receptor (PR) are important steroid hormone receptor biomarkers used to determine pr

209 The protein FKBP52 is a steroid hormone receptor coactivator likely involved in

210 ysine 4 (H3K4me1/2)(5,6), but also acts as a steroid hormone receptor coactivator through mechanisms

211 GT198 protein has been shown as a steroid hormone receptor coregulator and also as a cruci

212 l-by-cell basis by a specific isoform of the steroid hormone receptor ecdysone receptor-B2, for which

213 Mapping of steroid hormone receptor expression revealed that PNA mi

214 exhibited appropriate hormonal regulation of steroid hormone receptor expression.

215 dephosphorylation is required for kinase and steroid hormone receptor release from the chaperone comp

216 In breast and prostate cancers steroid hormone receptor signalling is the principal sti

217 gests a previously unidentified link between steroid hormone receptor signalling pathways and the reg

218 pared within the subgroups defined by cancer steroid hormone receptor status (ER and/or PR positive v

219 ficity of SGTA for additional members of the steroid hormone receptor superfamily and the mechanism b

220 The estrogen receptor (ER) is a steroid hormone receptor that acts as a transcription fa

221 ation between vegetable and fruit intake and steroid hormone receptor-defined breast cancer risk.

222 it intake could be associated with decreased steroid hormone receptor-negative breast cancer risk.

223 ago in the DNA-binding domain of an ancient steroid hormone receptor.

224 rgetable vulnerabilities in MBC, we examined steroid hormone receptors and tumor-infiltrating immune

225 Steroid hormone receptors are ligand-dependent transcrip

226 ide polymorphisms (SNP) in genes for the sex-steroid hormone receptors are not strongly associated wi

227 ynthesis are mediated by the membrane-bound, steroid hormone receptors G protein-coupled estrogen rec

228 The identification of lysine acetylation of steroid hormone receptors has previously been based on t

229 Steroid hormone receptors initiate a genetic program tig

230 ction with chromatin is likely shared by all steroid hormone receptors regardless of their capacity t

231 bility of pesticides to interfere with other steroid hormone receptors such as glucocorticoid recepto

232 otein ZNF764 acts as an enhancer for several steroid hormone receptors, and haploinsufficiency of thi

233 vitro activity, high selectivity over other steroid hormone receptors, and significant antidepressan

234 fferent pathways demonstrated alterations in steroid hormone receptors, steroidogenesis enzymes, and

235 by facilitating the access to chromatin for steroid hormone receptors, such as androgen receptor and

236 the context of transcriptional regulation by steroid hormone receptors, this review focuses on gene-s

237 n and biochemical assays to the evolution of steroid hormone receptors, we show that an ancient hydro

238 cals (EDCs) due to their ability to bind sex-steroid hormone receptors.

239 uitin-protein ligase and as a coactivator of steroid hormone receptors.

240 ignaling proteins including many kinases and steroid hormone receptors.

241 sduction, including many kinases and nuclear steroid hormone receptors.

242 mistry, including differential expression of steroid hormone receptors.

243 nes that modulate the signal transduction of steroid hormone receptors.

244 nes that modulate the signal transduction of steroid hormone receptors.

245 androgen signaling and is conserved in other steroid hormone receptors.

246 or a more comprehensive understanding of how steroid hormones regulate immunity and inflammation, a s

247 Steroid hormones regulate multiple but distinct aspects

248 tial mechanism leading to this dimorphism is steroid hormone regulated synthesis of transcripts encod

249 The brassinosteroid (BR) class of steroid hormones regulates plant development and physiol

250 Therefore, we examined ovarian steroid hormone regulation of GPR64 expression in the mu

251 Glucocorticoids (GCs) are steroid hormones released from the adrenal gland in resp

252 r immune modulation, reproductive cycle, and steroid hormone responsiveness in mice.

253 The affinity of lipidots for steroid hormone-rich areas is of interest to address dru

254 function in mice and possibly adrenocortical steroid hormone secretion in humans, beyond its recently

255 Thus, endogenous steroid hormone signaling in CD8(+) TILs promotes dysfun

256 We investigated the role of steroid hormone signaling in the brain on distinct featu

257 ur findings present a convergence of BMP and steroid hormone signaling pathways in the regulation of

258 l effects are mediated through the canonical steroid hormone signaling pathways.

259 beta and dorsal root ganglion cells and link steroid hormone signaling to insulin release and pain pe

260 r specific genes with important roles in sex steroid hormone signalling and function, and offer uniqu

261 of daf-2 (insulin/IGF-1 signalling), daf-12 (steroid hormone signalling), and eat-2 (putative dietary

262 molecular links between circadian clocks and steroid hormone signalling, although both are important

263 ity, with low levels of gonadotropic and sex steroid hormones, small testes or ovaries, impaired sper

264 Recent evidence has implicated steroid hormones, specifically estrogens, in the rapid m

265 expressed genes were enriched in response to steroid hormone stimulus and immune system development.

266 Sex steroid hormones such as 17beta-estradiol (estradiol) re

267 ral neuromodulators of memory processes, sex steroid hormones such as the potent oestrogen 17beta-oes

268 ole in determining the environmental fate of steroid hormones, such as 17beta-estradiol (E2).

269 Ovarian steroid hormones support the growth and maintenance of U

270 ces to mitochondria (Mito) for initiation of steroid hormone synthesis.

271 nduce free radical damage, which compromises steroid hormone synthesis.

272 increased expression of those of cholesterol/steroid hormone synthesis.

273 ial transport, cholesterol ester storage and steroid-hormone synthesis.

274 Mitofusin-1 and Mitofusin-2 are required for steroid-hormone synthesis.

275 strate androstenedione, unique among several steroid hormones, targeted TRPA1 in peptidergic primary

276 preregistered study tested the effect of the steroid hormone testosterone on moral dilemma judgements

277 al drugs pravastatin and artemether, and the steroid hormone testosterone.

278 RPM8 further confirmed direct binding of the steroid hormone, testosterone, to the TRPM8 protein.

279 ndogenous concentrations of estradiol, a sex steroid hormone that is known to influence UL risk.

280 lly transferred 20-hydroxy-ecdysone (20E), a steroid hormone that is produced by the male accessory g

281 -estradiol (E2 or estrogen) is an endogenous steroid hormone that is well known to exert neuroprotect

282 Estradiol (E2) is a steroid hormone that negatively affects muscle growth in

283 Progesterone is a steroid hormone that plays a central role in the female

284 (BRs) are a group of polyhydroxylated plant steroid hormones that are crucial for many aspects of a

285 Brassinosteroids are plant steroid hormones that control many aspects of plant grow

286 Brassinosteroids (BRs) are steroid hormones that coordinate fundamental development

287 Glucocorticoids are endogenous steroid hormones that regulate essential biological func

288 Glucocorticoids are steroid hormones that repress proinflammatory stimuli, b

289 thesized that Chst10 sulfates glucuronidated steroid hormone to regulate steroid hormone in vivo.

290 MTNL1 has a role in mediating the actions of steroid hormones to promote fiber switching in skeletal

291 Here, we explored whether steroid hormones to which human spermatozoa are exposed

292 the predominant "simple diffusion" model of steroid hormone transport across cell membranes.

293 Here, we used the cross-sex steroid hormone treatment of transsexuals seeking sex re

294 Significant suppression of multiple adrenal steroid hormones was also seen in treated children (redu

295 nvironmental fate of potent endocrine-active steroid hormones, we observed the formation of an intram

296 Elevated concentrations of the steroid hormones were associated with increased risk of

297 ies, males of some Anopheles species produce steroid hormones which are transferred to females during

298 al fluctuations in circulating levels of sex-steroid hormones, which are known to be potent neuromodu

299 Clinical response to glucocorticoids, steroid hormones widely used as pharmaceuticals, varies

300 ferred to clinically as corticosteroids) are steroid hormones with potent anti-inflammatory and immun