ライフサイエンスコーパス: steroid hormone receptor

1 ago in the DNA-binding domain of an ancient steroid hormone receptor.

2 of this peptide require interaction with the steroid hormone receptor.

3 duction molecules, in particular kinases and steroid hormone receptors.

4 members of the thyroid hormone subfamily of steroid hormone receptors.

5 promoting transcriptional activation by the steroid hormone receptors.

6 a eukaryotic transcriptional coactivator for steroid hormone receptors.

7 cals (EDCs) due to their ability to bind sex-steroid hormone receptors.

8 may regulate the transcriptional activity of steroid hormone receptors.

9 0/Hsc70) family proteins that interacts with steroid hormone receptors.

10 ogy domains of p85alpha, and extend to other steroid hormone receptors.

11 mechanism even in the presence of functional steroid hormone receptors.

12 ressors that mediate inducible repression by steroid hormone receptors.

13 t for activation of heterologously expressed steroid hormone receptors.

14 uitin-protein ligase and as a coactivator of steroid hormone receptors.

15 sor of the transcriptional activity of other steroid hormone receptors.

16 he activity of the tyrosine kinase v-Src and steroid hormone receptors.

17 esidues, is likely to be general for all the steroid hormone receptors.

18 70/Hsc70 family proteins that interacts with steroid hormone receptors.

19 n carcinomas, its expression is regulated by steroid hormone receptors.

20 ncentrations and differential expressions of steroid hormone receptors.

21 ion factors, which are members of the orphan steroid hormone receptors.

22 ignaling proteins including many kinases and steroid hormone receptors.

23 ell-established canonical machine regulating steroid hormone receptors.

24 y acting as transcriptional coactivator with steroid hormone receptors.

25 sduction, including many kinases and nuclear steroid hormone receptors.

26 mistry, including differential expression of steroid hormone receptors.

27 nes that modulate the signal transduction of steroid hormone receptors.

28 nes that modulate the signal transduction of steroid hormone receptors.

29 vo SMTNL1 selectively binds PR and not other steroid hormone receptors.

30 androgen signaling and is conserved in other steroid hormone receptors.

31 ulators has been established for the nuclear steroid hormone receptors.

32 volved in the maturation of many kinases and steroid hormone receptors.

33 ed receptors, receptor tyrosine kinases, and steroid hormone receptors.

34 ranscriptions 3 and 5 (STAT3 and STAT5), and steroid hormone receptors.

35 consistently produces a gain of function in steroid hormone receptors.

36 r younger patients with tumours that express steroid-hormone receptors.

37 amily, which was named SpSHR2 (S. purpuratus Steroid Hormone Receptor 2).

38 The broad distribution of sex steroid hormone receptors across diverse cell types and

39 by inhibiting p53 activity and by enhancing steroid hormone receptor action.

40 ding of hAgo2 is analogous to Hsp90-mediated steroid hormone receptor activation.

41 Genes involved in steroid hormone receptor activity and circadian rhythm w

42 aperone and target classes by assaying HSP70/steroid hormone receptor and CDC37/kinase interactions,

43 regated membrane versus nuclear actions of a steroid hormone receptor and demonstrated their in vivo

44 ers, it is likely no longer under control of steroid hormone receptors and becomes aberrantly express

45 and several other proteins, including Raf-1, steroid hormone receptors and certain tyrosine kinase gr

46 protein that binds the zinc finger region of steroid hormone receptors and enhances Sp1- and androgen

47 role of ATP hydrolysis in the maturation of steroid hormone receptors and kinases in vivo.

48 han 100-fold receptor selectivity over other steroid hormone receptors and LG120920 (7b) demonstrated

49 ety of proteins in eukaryotic cells, such as steroid hormone receptors and many other signal transduc

50 SRA is selective for steroid hormone receptors and mediates transactivation v

51 diverse cellular client proteins, including steroid hormone receptors and multiple oncogenic kinases

52 behavior in female rats and its influence on steroid hormone receptors and neurotransmitters in the f

53 mber of cellular signaling proteins, such as steroid hormone receptors and oncogene tyrosine kinases.

54 LECs express several steroid hormone receptors and PIBF1.

55 on of signal-transducing molecules including steroid hormone receptors and protein kinases.

56 mplex assembly of client proteins, including steroid hormone receptors and selected kinases.

57 t by members of the glucocorticoid family of steroid hormone receptors and suggest a model for the re

58 concentrations than previously observed with steroid hormone receptors and suggests that Cys2His2 zin

59 ding domain has shown it is similar to other steroid hormone receptors and that ligand binding alters

60 , which is required for interactions between steroid hormone receptors and the architectural HMG prot

61 reminiscent of hormone binding to classical steroid hormone receptors and the reverse of the pose ad

62 d hormones mediated by classic intracellular steroid hormone receptors and those mediated by a signal

63 A1 (FOXA1) modulates the transactivation of steroid hormone receptors and thus may influence tumor g

64 rgetable vulnerabilities in MBC, we examined steroid hormone receptors and tumor-infiltrating immune

65 otein ZNF764 acts as an enhancer for several steroid hormone receptors, and haploinsufficiency of thi

66 vitro activity, high selectivity over other steroid hormone receptors, and significant antidepressan

67 rsors, mediate their effects via non-classic steroid hormone receptors, and suggest that their develo

68 to its previously described interaction with steroid hormone receptors, and that it carries out some

69 ptors regulated by AKR1C members include the steroid hormone receptors (androgen, estrogen, and proge

70 of IgE synthesis by HC were inhibited by the steroid hormone receptor antagonist RU-486.

71 Models for Cdc37p regulation of steroid hormone receptors are discussed.

72 Sex steroid hormone receptors are expressed in the colon and

73 Steroid hormone receptors are ligand-binding transcripti

74 Steroid hormone receptors are ligand-dependent transcrip

75 ide polymorphisms (SNP) in genes for the sex-steroid hormone receptors are not strongly associated wi

76 Recognition sites for steroid hormone receptors are present in the 5' flanking

77 e signaling has focused on the mechanisms of steroid hormone receptors as they act as signaling molec

78 glucocorticoids and thyroid hormone use the steroid hormone receptor binding domain of CBP to stimul

79 and progesterone receptor (PR) are important steroid hormone receptor biomarkers used to determine pr

80 Ds) regulate the occupancy and activation of steroid hormone receptors by converting potent steroid h

81 including p53, Hox transcription factors and steroid hormone receptors, by increasing their affinity

82 etroviral Zn-coordinating residues (CCHC) to steroid hormone receptor (CCCC) or transcription factor

83 Unlike the steroid hormone receptor coactivator 1 (SRC1), beta-cate

84 e repression effect of Ear-2 was reversed by steroid hormone receptor coactivator 1.

85 PV mouse), we investigated the effect of the steroid hormone receptor coactivator 3 (SRC-3) on RTH.

86 The protein FKBP52 is a steroid hormone receptor coactivator likely involved in

87 osophila gene, named taiman, which encodes a steroid hormone receptor coactivator related to AIB1.

88 ysine 4 (H3K4me1/2)(5,6), but also acts as a steroid hormone receptor coactivator through mechanisms

89 Best established as components of steroid hormone receptor complexes, it is now clear that

90 Similar to certain unliganded steroid hormone receptor complexes, the unliganded aryl

91 activity and is a component of a subclass of steroid hormone receptor complexes.

92 GT198 protein has been shown as a steroid hormone receptor coregulator and also as a cruci

93 mone transcriptional effects are mediated by steroid hormone receptor coregulators that also modify a

94 ation between vegetable and fruit intake and steroid hormone receptor-defined breast cancer risk.

95 The 26S proteasome modulates steroid hormone receptor-dependent gene transcription at

96 -4,9-dien-3- one) pretreatment, suggesting a steroid hormone receptor-dependent process.

97 Gene regulation by steroid hormone receptors depends on the particular char

98 l-by-cell basis by a specific isoform of the steroid hormone receptor ecdysone receptor-B2, for which

99 expression in MB neuroblasts, and extrinsic steroid hormone receptor (EcR) activation boosts E93 lev

100 has implicated the gene encoding the nuclear steroid hormone receptor ESRRG as a candidate gene for C

101 Steroid hormone receptor expression observed in vitro pa

102 Mapping of steroid hormone receptor expression revealed that PNA mi

103 noids in a three-dimensional matrix, a lower steroid hormone receptor expression, and higher telomera

104 exhibited appropriate hormonal regulation of steroid hormone receptor expression.

105 bed MCP-1 mRNA, whereas other members of the steroid hormone receptor family did not.

106 Androgen receptor (AR) is a member of the steroid hormone receptor family of molecules.

107 receptor (VDR), a member of the nuclear and steroid hormone receptor family, have been linked to hum

108 rategy is extendable to other members of the steroid hormone receptor family.

109 rogen receptor alpha, is a new member of the steroid hormone receptor family.

110 mal cell proliferation and the expression of steroid hormone receptors for estrogen (ESR1, also known

111 ous studies linking CRT to downregulation of steroid hormone receptor function led us to examine its

112 The nuclear and steroid hormone receptors function as ligand-dependent t

113 Steroid hormone receptors function classically in the nu

114 ynthesis are mediated by the membrane-bound, steroid hormone receptors G protein-coupled estrogen rec

115 id hormone receptor (T3R) is a member of the steroid hormone receptor gene family of nuclear hormone

116 interactions of four distinct clients, i.e., steroid hormone receptors (glucocorticoid receptor and m

117 g sites, each of which are overlapped by two steroid hormone receptor half-sites, and a shared AP1 co

118 The identification of lysine acetylation of steroid hormone receptors has previously been based on t

119 The estrogen receptor (ER), a steroid hormone receptor important in female physiology,

120 nd support the important role of nuclear sex steroid hormone receptors in modulating social behaviors

121 ts suggest a new functional paradigm whereby steroid hormone receptors in particular and ID proteins

122 between high mobility group box proteins and steroid hormone receptors in regulating tissue-specific

123 l for studying transcriptional regulation by steroid hormone receptors in the context of chromatin.

124 there are also non-nuclear subpopulations of steroid hormone receptors, including estrogen receptors

125 east cancer cell growth in part by targeting steroid hormone receptors, including progesterone recept

126 Steroid hormone receptors initiate a genetic program tig

127 Gene activation by steroid hormone receptors involves the recruitment of th

128 pha knockout (ERKO) mice suggested that this steroid hormone receptor is required in the mammary stro

129 -dependent transactivation by several of the steroid hormone receptors is potentiated by the Hsp90-as

130 ce the activation pathway for p60(v-src) and steroid hormone receptors is similar, the present study

131 the first transcription factors, other than steroid hormone receptors, known to be required for ovar

132 igned Cys(2)-His(2) zinc finger proteins and steroid hormone receptor ligand binding domains.

133 However, with the exception of steroid hormone receptors, little information exists abo

134 fferential splicing effects, suggesting that steroid hormone receptors may simultaneously control gen

135 ediated, at least in part, through a classic steroid hormone receptor mechanism.

136 a related protein, CAPERbeta, regulate both steroid hormone receptor-mediated transcription and alte

137 A activator (SRA) is an RNA that coactivates steroid hormone receptor-mediated transcription in vitro

138 Constitutive steroid hormone receptor mRNA levels were determined for

139 specific labeling for either type of gonadal steroid hormone receptor mRNA.

140 it intake could be associated with decreased steroid hormone receptor-negative breast cancer risk.

141 tumors, protein kinases are upregulated and steroid hormone receptors often function independently o

142 sted that the signature motif, LXXLL, within steroid hormone receptor p160 coregulators may play impo

143 sal women with axillary lymph node-positive, steroid hormone receptor-positive breast cancer (1,503 e

144 ctive adjuvant approaches for premenopausal, steroid hormone receptor-positive breast cancer.

145 The ligand-binding domains of steroid hormone receptors possess a conserved structure

146 tyrosine kinase growth factor receptors, and steroid hormone receptors, possibly by virtue of its abi

147 ated through interactions of SMTNL1 with the steroid hormone receptor PR-B.

148 on to enhancing or repressing transcription, steroid hormone receptors rapidly transduce kinase activ

149 Our data suggest that activated steroid hormone receptors recruit coregulators to the ta

150 ction with chromatin is likely shared by all steroid hormone receptors regardless of their capacity t

151 These results indicate that steroid hormone receptor-regulated transcription and pre

152 dephosphorylation is required for kinase and steroid hormone receptor release from the chaperone comp

153 A search for possible coactivators for steroid hormone receptors resulted in identification of

154 egions within the hormone binding domains of steroid hormone receptors resulting in different biologi

155 data from a combinatorial DMS of an ancient steroid hormone receptor's capacity to activate transcri

156 t of specific ELMs and their PTMs within the steroid hormone receptor (SHR) family, while highlightin

157 Steroid hormone receptors (SHR) are crucial regulators o

158 its ability to potentiate transactivation by steroid hormone receptors (SHR).

159 Steroid hormone receptors (SHRs) and nuclear receptors (

160 Steroid hormone receptors (SHRs) are ligand-activated tr

161 They also identify CCNA2 as a coregulator of steroid hormone receptor signaling and suggest that impa

162 In breast and prostate cancers steroid hormone receptor signalling is the principal sti

163 gests a previously unidentified link between steroid hormone receptor signalling pathways and the reg

164 ogate how DNA recognition diversified in the steroid hormone receptor (SR) family.

165 Steroid hormone receptors (SRs) are ligand-activated tra

166 Steroid hormone receptors (SRs) are transcription factor

167 pared within the subgroups defined by cancer steroid hormone receptor status (ER and/or PR positive v

168 fferent pathways demonstrated alterations in steroid hormone receptors, steroidogenesis enzymes, and

169 trong interaction with AR but not with other steroid hormone receptors such as estrogen receptor alph

170 bility of pesticides to interfere with other steroid hormone receptors such as glucocorticoid recepto

171 show that the nuclear export pathway used by steroid hormone receptors such as GR is distinct from th

172 enhance the transcriptional activity of some steroid hormone receptors such as the androgen receptor

173 ver of many transcription factors, including steroid hormone receptors such as the estrogen receptor

174 by facilitating the access to chromatin for steroid hormone receptors, such as androgen receptor and

175 Transcription activation by steroid hormone receptors, such as the androgen receptor

176 sspeptin neurons in the hypothalamus express steroid hormone receptors, suggesting hormone action on

177 ficity of SGTA for additional members of the steroid hormone receptor superfamily and the mechanism b

178 nuclear receptors that belong to the thyroid-steroid hormone receptor superfamily.

179 osophila encode transcription factors in the steroid hormone receptor superfamily.

180 ranscription factors that are members of the steroid hormone receptor superfamily.

181 C-1 is a coactivator for many members of the steroid-hormone receptor superfamily of ligand-inducible

182 ted receptor alpha (PPAR) is a member of the steroid/hormone receptor superfamily that mediates the p

183 The estrogen receptor (ER) is a steroid hormone receptor that acts as a transcription fa

184 MR is a steroid hormone receptor that detects circulating glucoc

185 Thus there exist pools of transmembrane steroid hormone receptors that are efficient signaling m

186 Like other steroid hormone receptors, the regulation of target gene

187 the context of transcriptional regulation by steroid hormone receptors, this review focuses on gene-s

188 f transcriptional coactivators interact with steroid hormone receptors to enhance ligand-dependent tr

189 beyond the important cell nuclear actions of steroid hormone receptors to include signaling pathways

190 eins may use distinct mechanisms to modulate steroid hormone receptor transactivation.

191 ate that the ability of hPRA to transrepress steroid hormone receptor transcriptional activity and it

192 ligand-dependent transdominant repressor of steroid hormone receptor transcriptional activity.

193 efine the mechanism by which hPR-A modulates steroid hormone receptor transcriptional activity.

194 nection between the stress MAPK pathways and steroid hormone receptor VDR expression and thereby offe

195 teroidogenic enzymes, down-stream signal and steroid hormone receptors was assessed by Real-time PCR.

196 urrently, transcript expression of the three steroid hormone receptors was studied by reverse transcr

197 n and biochemical assays to the evolution of steroid hormone receptors, we show that an ancient hydro

198 All steroid hormone receptors were found in key brain region

199 e crosstalks between androgen, estrogen, and steroid hormone receptors, whereas the presence of estro

200 as probes for the structure and function of steroid hormone receptors which contain Cys2Cys2 zinc fi

201 ding pocket is larger than the corresponding steroid hormone receptors, which allows T0901317 to adop

202 ese gonadal hormones are mediated by nuclear steroid hormone receptors, which are crucial for integra

203 that treatment of human cancer cells having steroid hormone receptors with the appropriate hormone,

204 l imaging has revealed the rapid mobility of steroid hormone receptors within nuclei and their dynami