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1 cancer and encodes a protein that acts as a steroid receptor coactivator.
2 interacts with LXXLL motifs (NR box) in p160 steroid receptor coactivators.
3 plicing in a manner differing from the other steroid receptor coactivators.
5 receptor beta (TRbeta) gene that cannot bind steroid receptor coactivator 1 (SRC-1) and Src-1(-/-) mi
6 gh inhibition of PR-dependent recruitment of steroid receptor coactivator 1 (SRC-1) and subsequent hi
7 e also demonstrate that UBCH7 interacts with steroid receptor coactivator 1 (SRC-1) and that UBCH7 co
8 cooperation of the coactivators CBP/p300 and steroid receptor coactivator 1 (SRC-1) and the p300/CBP-
9 nce analysis reveals that RAC3 is related to steroid receptor coactivator 1 (SRC-1) and transcription
12 oic acid receptor, CREB-binding protein, and steroid receptor coactivator 1 (SRC-1) in cell transfect
14 y less ability than dexamethasone to trigger steroid receptor coactivator 1 (SRC-1) recruitment and h
15 risk HPV type 16 (HPV16) E7 oncoprotein with steroid receptor coactivator 1 (SRC-1), an essential com
16 nterestingly, this domain corresponds to the steroid receptor coactivator 1 (SRC-1)-interacting domai
22 coactivators, CREB-binding protein (CBP) and steroid receptor coactivator 1 (SRC-1, a member of the p
24 coid receptor interacting protein 1 (GRIP1), steroid receptor coactivator 1 (SRC-1a), and SRC-1e bind
25 eciphered a previously unappreciated role of Steroid receptor coactivator 1 (SRC1) in defining the li
26 tion, antibodies directed against the cloned steroid receptor coactivator 1 (SRC1) recognize ERAP160.
27 -dependent recruitment of a peptide from the steroid receptor coactivator 1 (SRC1) to the nuclear rec
28 iquitination greatly enhanced recruitment of steroid receptor coactivator 1 (SRC1), a coactivator cri
29 ement binding protein binding protein (CBP), steroid receptor coactivator 1 (SRC1), and protein argin
30 n and corresponds precisely with the minimal steroid receptor coactivator 1 (SRC1)-interacting domain
33 lular nuclear receptor coactivators, such as steroid receptor coactivator 1 and p300/CREB-binding pro
34 ARQ48 aggregates sequester mitochondria and steroid receptor coactivator 1 and stain positively for
36 ation of VDR with the coactivators GRIP1 and steroid receptor coactivator 1 in vitro but had little o
37 ed the transcriptional coactivators p300 and steroid receptor coactivator 1 less efficiently than ros
38 TCO-mediated interaction between CAR and the steroid receptor coactivator 1 or the glucocorticoid rec
39 D bound to DAC and the fourth LXXLL motif of steroid receptor coactivator 1 reveals that the GR ligan
40 tryptophan-299 to activate hPXR; 5) recruits steroid receptor coactivator 1 to hPXR; 6) activates hPX
41 ated the recruitment of TTF-1, p65, CBP, and steroid receptor coactivator 1 to the TBE region of the
51 CI, Gao and colleagues present evidence that steroid receptor coactivators 1 and 2 (SRC-1 and SRC-2)
53 r, cotransfection of SNURF with prototypical steroid receptor coactivators 1, 2, and 3 that contain L
54 Also, coactivator binding studies with a steroid receptor coactivator-1 (receptor interaction dom
56 that includes the histone acetyltransferases steroid receptor coactivator-1 (SRC-1) and CREB binding
59 to interact with two other coactivators, the steroid receptor coactivator-1 (SRC-1) and the peroxisom
60 activated receptor binding protein (PBP) and steroid receptor coactivator-1 (SRC-1) are required for
61 mouse liver cDNA library and have identified steroid receptor coactivator-1 (SRC-1) as a PPAR transcr
63 25 amino acid residue fragment of the human steroid receptor coactivator-1 (SRC-1) containing one LX
66 coactivators CREB-binding protein (CBP) and steroid receptor coactivator-1 (SRC-1) for maximal activ
67 tigated further the coactivator functions of steroid receptor coactivator-1 (SRC-1) in terms of its f
68 yzed roles of CREB-binding protein (CBP) and steroid receptor coactivator-1 (SRC-1) in TTF-1 regulati
72 o part of the active receptor complex is the steroid receptor coactivator-1 (SRC-1) which interacts w
75 hat interacts only with coactivators such as steroid receptor coactivator-1 (SRC-1), RU486-bound PR b
76 During the decade since the discovery of steroid receptor coactivator-1 (SRC-1), the first authen
77 lpha), which requires co-activators, such as steroid receptor coactivator-1 (SRC-1), to facilitate th
78 ude p300 and CREB-binding protein (CBP), the steroid receptor coactivator-1 (SRC-1)-related family of
87 r activator RNA 1 (SRA1) that is part of the steroid receptor coactivator-1 acetyltransferase complex
88 , nuclear receptor coactivators p300/CBP and steroid receptor coactivator-1 act individually as well
90 e interactions of hCAR with the coactivators steroid receptor coactivator-1 and glucocorticoid recept
91 eases the functional interaction between the steroid receptor coactivator-1 and hPXR but not mouse PX
92 rinsic activity of p160 coactivators such as steroid receptor coactivator-1 and promoted the interact
93 y between PBP and other coactivators such as steroid receptor coactivator-1 and that PBP plays a crit
94 ently identified to be highly related to the steroid receptor coactivator-1 and transcriptional inter
95 , transcriptional intermediate factor 2, and steroid receptor coactivator-1 are expressed in specific
96 e nuclear receptor interacting domain of the steroid receptor coactivator-1 as a model for exploring
97 and promoted the interaction between PR and steroid receptor coactivator-1 in a mammalian two-hybrid
101 ene and also remarkably reduces basal MR and steroid receptor coactivator-1 recruitment, unraveling a
103 t insulin facilitated the recruitment of the steroid receptor coactivator-1 to the SREBP-1c promoter.
104 interaction with fatty acid metabolites and steroid receptor coactivator-1 while increasing PPARalph
105 ion of the complex between ERR gamma and the steroid receptor coactivator-1, and led to an inhibition
107 d to spironolactone, finerenone inhibits MR, steroid receptor coactivator-1, and RNA polymerase II bi
108 glucose increased PPARalpha interaction with steroid receptor coactivator-1, DNA binding, and transac
109 functional synergy of the p160 coactivators [steroid receptor coactivator-1, glucocorticoid receptor
110 to bind the IL-4 promoter in the presence of steroid receptor coactivator-1, indicating that PPARalph
111 element-binding protein-binding protein and steroid receptor coactivator-1, participate in both the
112 BD interacted with the C-terminal portion of steroid receptor coactivator-1, they did not enhance the
113 ion of the retinoid X receptor decreases the steroid receptor coactivator-1-dependent thyroid hormone
114 icoid-receptor-interactive protein-1(GRIP-1)/steroid-receptors coactivator-1 (SRC-1)) without breakin
115 ly of nuclear receptor coactivators, such as steroid receptor coactivator 1a and glucocorticoid recep
116 gate binding and dissociation of full-length steroid receptor coactivator-1a (SRC1a) from full-length
118 of the oncogenic transcriptional coregulator steroid receptor coactivator 2 (SRC-2), also known as NC
119 rs that block the association of TRbeta with steroid receptor coactivator 2 (SRC2), we identified a n
120 ding between VDR and a fluorescently labeled steroid receptor coactivator 2 peptide was applied to di
121 corporated them into a sequence derived from steroid receptor coactivator 2, which interacts with est
123 t-binding protein (CREB)-binding protein and steroid receptor coactivators 2 and 3 was decreased in f
124 reviously demonstrated the potential role of steroid receptor coactivator-2 (SRC-2) as a co-regulator
125 sly shown that the transcriptional regulator steroid receptor coactivator-2 (SRC-2) controls activati
126 y androgen receptor (AR) and its coregulator steroid receptor coactivator-2 (SRC-2) enhances mitochon
129 es and in HepG2 cells reduced recruitment of steroid receptor coactivator-2 by RORalpha at an endogen
135 that ERK3 interacted with and phosphorylated steroid receptor coactivator 3 (SRC-3), an oncogenic pro
136 rect interaction of the liganded TRbeta with steroid receptor coactivator 3 (SRC-3), which recruits p
140 e of an active complex of DNA-bound ERalpha, steroid receptor coactivator 3 (SRC-3/NCOA3), and a seco
142 proteins, including androgen receptor (AR), steroid receptor coactivator 3 (SRC3) and BRD4, for degr
143 of purified full-length PR and intact CoRs, steroid receptor coactivator 3 (SRC3) and p300, as compl
144 as a model, we have investigated the role of steroid receptor coactivator 3 (SRC3) in gene activation
145 Here, we report that the ER coactivator steroid receptor coactivator 3 (SRC3) is also a coactiva
147 enced by histone acetylation and require the steroid receptor coactivator 3 (SRC3), which mediates in
148 ctivation of gene expression was enhanced by steroid receptor coactivator 3 coactivator, and required
150 ied in breast cancer 1 (AIB1), also known as steroid receptor coactivator 3 or NCOA3, is a transcript
151 parate assays, both the recruitment of SRC3 (steroid receptor coactivator 3, a transcriptional coacti
152 gh-throughput screening to identify SMIs for steroid receptor coactivator-3 (SRC-3 or AIB1), a large
153 In the present study, we find that high steroid receptor coactivator-3 (SRC-3) expression is cor
155 Molecular Cell, Yu et al. reported that the steroid receptor coactivator-3 (SRC-3) has a novel cytop
156 ctivator amplified in breast cancer 1 (AIB1)/steroid receptor coactivator-3 (SRC-3) have been shown t
157 ent study aimed to elucidate the role of the steroid receptor coactivator-3 (SRC-3) in thyroid carcin
158 oncogene amplified in breast cancer 1 (AIB1)/steroid receptor coactivator-3 (SRC-3) induces mammary t
166 y also caused a failure in downregulation of steroid receptor coactivator-3 (SRC-3), a potent ERalpha
172 sphorylated alternate-spliced isoform of the steroid receptor coactivator-3 (SRC-3Delta4) bridges EGF
173 d crystallographic studies, we identify that steroid receptor coactivator-3 (SRC3) (also named as amp
174 exes did not readily recruit the coactivator steroid receptor coactivator-3 (SRC3) or ER to the PS2 p
175 er region for recruiting nuclear coactivator steroid receptor coactivator-3 and p300 for histone epig
176 ociated with the displacement of ERalpha and steroid receptor coactivator-3 from the target EBRs lead
177 shown that TR recruits the coactivator SRC3 (steroid receptor coactivator-3) and that coactivator rec
178 ceptor-associated coactivator 3 (RAC3)/AIB-1/steroid receptor coactivator-3, a nuclear coregulator an
182 R function by selectively competing with the steroid receptor coactivator AIB1 but not GRIP1 or SRC1
185 eroid receptors, it has been identified as a steroid receptor coactivator, and was thought not to be
186 s reactivation of mutant p53, stimulation of steroid receptor coactivators, and induction of protein
187 enotypes indicate that these two families of steroid receptor coactivators are not functionally equiv
188 sferase (HAT) domain, EIA-binding domain and steroid-receptor coactivator binding domains of CBP.
190 xes, DRIP (VDR-interacting protein) and SRC (steroid receptor coactivator), during keratinocyte diffe
191 or complex disassembly by methylation of the steroid receptor coactivator family coactivators and p30
196 ominent among these coactivators is the SRC (steroid receptor coactivator) family, which consists of
197 refore, SRC-3, a third member of a family of steroid receptor coactivators, has a distinct tissue dis
199 a novel function of Cdc25B that serves as a steroid receptor coactivator in addition to its role as
202 the most active members inhibit the ERalpha/steroid receptor coactivator interaction with K i's in t
203 ty and the C-terminal region (containing the steroid receptor coactivator/p160-binding region and the
204 s induced by GR signaling, and the important steroid receptor coactivator PELP1 was also found to be
205 (Pol II), estrogen receptor alpha (ERalpha), steroid receptor coactivator proteins (SRC), and acetyla
206 een the AR N and C termini or recruitment of steroid receptor coactivator proteins (SRC-1 or -2), alt
209 ctivator REGgamma directs degradation of the steroid receptor coactivator SRC-3 by the 20S proteasome
210 ctivator REGgamma directs degradation of the steroid receptor coactivator SRC-3 by the 20S proteasome
212 in the recruitment of RNA polymerase II and steroid receptor coactivators SRC-2 and SRC-3, and chang
214 ne (JH) receptor, Methoprene-tolerant (Met), steroid receptor coactivator (SRC) and GATAa but not ecd
215 tivators, VDR-interacting protein (DRIP) and steroid receptor coactivator (SRC) at different stages o
216 mains of transcription factors, those of the steroid receptor coactivator (SRC) family are poorly cha
217 invasion, and metastasis, including the p160 steroid receptor coactivator (SRC) family composed of SR
219 ne receptor (TR) include members of the p160/steroid receptor coactivator (SRC) family of proteins, p
221 ied of these coactivators are members of the steroid receptor coactivator (SRC) family, SRC-1, TIF2/G
224 the bHLH transcription factors studied, the steroid receptor coactivator (SRC) showed the most sever
225 cetyltransferase complexes, such as p300/CBP-steroid receptor coactivator (SRC), as well as the multi
226 rene-tolerant transcription factor (Met) and steroid receptor coactivator (SRC), would be expressed c
229 lencing mediator for retinoid and thyroid or steroid receptor coactivator (SRC)-1 with RARalpha versu
230 OOH-terminal interaction and are enhanced by steroid receptor coactivator (SRC)-1, whereas the bicalu
231 gamma) regulate bone metabolism, and because steroid receptor coactivator (SRC)-2 (TIF-2) enhances ER
233 phosphorylation signaling pathway involving steroid receptor coactivator (Src)-mitogen-activated pro
235 ne receptors involves the recruitment of the steroid receptor coactivator (SRC)/p160 coactivator LXXL
236 R FXXLF motif binding and the recruitment of steroid receptor coactivator (SRC)/p160 coactivator LXXL
237 further dissect the roles of members of the steroid receptor coactivator (SRC)/p160 family in PR-med
238 eam target of progesterone receptor (PR) and steroid receptor coactivator (SRC-1) action in the uteru
241 growth pathways on which cancer cells rely, steroid receptor coactivators (SRC-1, SRC-2, and SRC-3)
243 interplay and demonstrated that it requires steroid receptor coactivators (SRC-2, SRC-3) and the med
245 man (Tai) protein is homologous to the human steroid-receptor coactivators SRC1-3 and activates trans
246 ray by immunofluorescence were two different steroid receptor coactivators (SRC1 and CBP) with acetyl
247 B-613, a potent small molecule stimulator of steroid receptor coactivators (SRCs) attenuates patholog
248 gate functional relationships between PR and steroid receptor coactivators (SRCs) in distinct cell ty
250 of nuclear receptors and suggested that the steroid receptor coactivators (SRCs) play an important r
254 cription factors, and their association with steroid receptor coactivators (SRCs) upon binding to DNA
259 ranscription that is a member of a family of steroid receptor coactivators that includes SRC-1 and tr
260 ry gland development observed previously for steroid receptor coactivator type 1 (SRC-1) and SRC-3 fe
263 ruitment of yellow fluorescent protein (YFP)-steroid receptor coactivators (YFP-SRC-1 and YFP-CREB bi