ライフサイエンスコーパス: steroidogenic

1 Steroidogenic 17beta-HSD2 inhibition thus enables target

2 sted by ritonavir (LPV/r) is associated with steroidogenic abnormalities.

3 Wild-type StAR increased steroidogenic activity by 7-9-fold compared to mutant R1

4 Elevated latent prenatal steroidogenic activity has been found in the amniotic fl

5 , extending the finding of elevated prenatal steroidogenic activity in autism.

6 the first direct evidence of elevated fetal steroidogenic activity in autism.

7 ituitary-adrenal axis resulting in increased steroidogenic activity in the adrenal cortex and an elev

8 nt lost all cholesterol binding capacity and steroidogenic activity with isolated mitochondria in vit

9 arotenoid-binding protein (CBP), a member of steroidogenic acute regulatory (StAR) protein family wit

10 f PDE8s and PDE4 increased the expression of steroidogenic acute regulatory (StAR) protein.

11 Steroidogenic acute regulatory (StAR) proteins in steroi

12 gulation of progesterone production, such as steroidogenic acute regulatory factor (Star).

13 xpression of the steroidogenic gene products steroidogenic acute regulatory protein (StAR) and melano

14 The steroidogenic acute regulatory protein (StAR) belongs to

15 The steroidogenic acute regulatory protein (StAR) controls t

16 the same promoter region of the CYP17A1 and steroidogenic acute regulatory protein (StAR) genes.

17 gers the interaction of 14-3-3gamma with the steroidogenic acute regulatory protein (STAR) in the cyt

18 The steroidogenic acute regulatory protein (StAR) is require

19 5alpha-THP with the cholesterol transporters steroidogenic acute regulatory protein (StAR) or translo

20 The steroidogenic acute regulatory protein (StAR) simulates

21 Steroidogenic acute regulatory protein (StAR) stimulates

22 In acute stress or hormonal stimulation, steroidogenic acute regulatory protein (StAR) transports

23 of outer mitochondrial membrane 22 (Tom22), steroidogenic acute regulatory protein (StAR), and 3beta

24 eased mRNAs of melanocortin receptor type 2, steroidogenic acute regulatory protein (StAR), and gene

25 ther key steroidogenic transcripts including steroidogenic acute regulatory protein (STAR), cytochrom

26 The steroidogenic acute regulatory protein (StAR), the first

27 Expression of steroidogenic acute regulatory protein (StAR), the rate-

28 e transcription factors c-Fos/c-Jun regulate steroidogenic acute regulatory protein (StAR), which fac

29 tivating protein, STARD10 is a member of the steroidogenic acute regulatory protein (StAR)-related li

30 rial and cytosolic components, including the steroidogenic acute regulatory protein (STAR).

31 steroids in response to stress, requires the steroidogenic acute regulatory protein (StAR).

32 pha); and the hormone-induced PKA substrate, steroidogenic acute regulatory protein (StAR).

33 ndrial cholesterol transport mediated by the steroidogenic acute regulatory protein (StAR).

34 ein levels of SREBP2, HMG-CoA reductase, and steroidogenic acute regulatory protein (StAR; a protein

35 We investigated the involvement of steroidogenic acute regulatory protein (STARD1), a mitoc

36 The expression of steroidogenic acute regulatory protein decreased during

37 attenuated GX sPLA2-dependent inhibition of steroidogenic acute regulatory protein expression and pr

38 was probably explained by reduced testicular steroidogenic acute regulatory protein expression, which

39 sing liver X receptor-mediated activation of steroidogenic acute regulatory protein expression.

40 he reduction of testosterone levels, because steroidogenic acute regulatory protein is crucial for te

41 The Star (steroidogenic acute regulatory protein)-related transfer

42 enesis (evaluated by levels of testosterone, steroidogenic acute regulatory protein, 3beta-hydroxyste

43 K activation and subsequent up-regulation of steroidogenic acute regulatory protein, a steroid transp

44 eceptor accessory protein messenger RNAs and steroidogenic acute regulatory protein, and a reduction

45 ts of cholesterol utilization, including the steroidogenic acute regulatory protein, StAR, a novel LX

46 nal corticosterone levels and an increase in steroidogenic acute regulatory protein, steroidogenic fa

47 nal glands were collected for measurement of steroidogenic acute regulatory protein, steroidogenic fa

48 nd that amino acids 79-271 of LPCAT1 and the steroidogenic acute regulatory protein-related lipid tra

49 ecutive hotdog-fold domains and a C-terminal steroidogenic acute regulatory protein-related lipid tra

50 cific cholesterol carriers, particularly the steroidogenic acute regulatory protein.

51 The steroidogenic acute regulatory-related lipid-transfer (S

52 1-deleted cells and our studies suggest that steroidogenic adrenal cells during foetal stages require

53 press Gli1, a known marker of progenitors of steroidogenic adrenal cells.

54 nown as NR5A1) is a crucial mediator of both steroidogenic and nonsteroidogenic tissue differentiatio

55 Models for steroidogenic and thyroid-related effects could not be d

56 omal cytochromes P450 that catalyze critical steroidogenic and xenobiotic reactions, and to two heme

57 A ToxCast HTS assays for estrogen, androgen, steroidogenic, and thyroid-disrupting mechanisms to clas

58 A ToxCast HTS assays for estrogen, androgen, steroidogenic, and thyroid-disrupting mechanisms to clas

59 anisms of toxicity include disruption of the steroidogenic biosynthesis pathway and oxidative stress.

60 number, distribution, and most importantly, steroidogenic capacity and suggest that abnormal express

61 es exhibited decreased fertility, testicular steroidogenic capacity, and spermatogenesis that were mo

62 These studies reveal the complex nature of steroidogenic cell differentiation during urogenital dev

63 ein are expressed at varying levels in model steroidogenic cell lines and the adrenal, with only low

64 absence of TSPO in different mouse and human steroidogenic cell lines had no effect on steroidogenesi

65 selective HDL CE uptake mediated by SR-BI in steroidogenic cell lines.

66 Import of TSPO into steroidogenic cell mitochondria is regulated by cAMP.

67 The level of import of TSPO into steroidogenic cell mitochondria was increased following

68 etween the mesonephros and the gonad harbors steroidogenic cell precursors that are repressed by the

69 To circumvent this issue, steroidogenic cell-targeting Nr5a1-Cre mice were crossed

70 ed for the first time, rendering adipocyte a steroidogenic cell.

71 two separate origins of adult adrenocortical steroidogenic cells (fetal adrenal cortex and/or the adr

72 Whole bovine tissues, isolated ovarian steroidogenic cells (granulosa, theca, small luteal, and

73 Supporting cells (Sertoli and granulosa) and steroidogenic cells (Leydig and theca-interstitium) are

74 lasts and COS-7 kidney) but not in TSPO-rich steroidogenic cells (MA-10 Leydig) with high basal Tspo

75 ed basal Tspo promoter activity in TSPO-rich steroidogenic cells (MA-10 Leydig), as well as basal and

76 Using isolated mitochondria from steroidogenic cells and cell-free synthesized AS, we fir

77 plantation phenotype to the clock in ovarian steroidogenic cells and distinguishes it from more gener

78 eproduction by its actions to affect ovarian steroidogenic cells and to induce apoptosis of corpus lu

79 idogenic acute regulatory (StAR) proteins in steroidogenic cells are implicated in the delivery of ch

80 Corticotropin was detected in steroidogenic cells arranged in clusters that were disse

81 determination caused ectopic development of steroidogenic cells at the embryonic stage.

82 alpha-OOH can be transported to/into Mito of steroidogenic cells by StAR proteins and therein induce

83 1a1 reporter mice, we definitively show that steroidogenic cells can migrate from the mesonephros int

84 Insl3 showing that they are a population of steroidogenic cells distinct from Leydig cells.

85 ital ridge somatic cells differentiated into steroidogenic cells in both male and female gonads.

86 pin, which is produced by a subpopulation of steroidogenic cells in the hyperplastic adrenals.

87 idogenic cortex, which reduced the number of steroidogenic cells in the zona fasciculata of the adren

88 ed and the somatic cells differentiated into steroidogenic cells instead of supporting cells.

89 recently showed that high levels of TSPO in steroidogenic cells may be due to high constitutive expr

90 ata suggest that elevated TSPO expression in steroidogenic cells may be due to high constitutive expr

91 Steroidogenic cells of the adrenal and gonad are thought

92 irst demonstration via lineage analysis that steroidogenic cells originate from nephrogenous mesenchy

93 cretory and glandular tissues, especially in steroidogenic cells, and its expression is altered in ce

94 about SR-BI posttranslational regulation in steroidogenic cells, we examined the roles of Na(+)/H(+)

95 n other bovine tissues, including follicular steroidogenic cells.

96 teristics of lipid droplets (LDs) in ovarian steroidogenic cells.

97 cretory and glandular tissues, especially in steroidogenic cells.

98 nchyme contributes to both Sertoli cells and steroidogenic cells.

99 steroid-producing fetal Leydig cells and non-steroidogenic cells.

100 hat capsular RSPO3 signals to the underlying steroidogenic compartment to induce beta-catenin signali

101 All steroidogenic components were present, although only ker

102 into two distinct domains before meiosis: a steroidogenic core (the female medulla), overlain by the

103 ic GATA4- and Gli1-positive cells within the steroidogenic cortex, which reduced the number of steroi

104 Co-transfection of non-steroidogenic COS-1 cells with P450c17 and p38 expressio

105 ormation in both steroidogenic MA-10 and non-steroidogenic COS-F2-130 cells that were engineered to m

106 The importance of selectivity over other steroidogenic CYP enzymes, in particular 11beta-hydroxyl

107 It up-regulates the expression of the steroidogenic Cyp11a1 gene in the adrenal in a pathway s

108 econd electron from cytochrome b5, for human steroidogenic CYP17A1, the cytochrome P450 reductase FMN

109 and the catalytic domain of the bifunctional steroidogenic cytochrome P450 17A1 (CYP17A1) were invest

110 for certain structural features of the human steroidogenic cytochrome P450 17A1 (CYP17A1).

111 he cross-reactivity of drugs across multiple steroidogenic cytochrome P450 enzymes, provide a structu

112 ny mutations that are found in patients with steroidogenic diseases, the active site reveals multiple

113 the human fetal testis is insensitive to the steroidogenic effects of phthalates, the effects on germ

114 roendocrine, immunomodulatory, metabolic and steroidogenic effects to that of leptin is consistent wi

115 d residence time is a key factor determining steroidogenic efficacy of TSPO-binding compounds.

116 arvested and assessed for histopathology and steroidogenic end points.

117 used antifungal chemical that inhibits a key steroidogenic enzyme [cytochrome P450(CYP19) aromatase]

118 The steroidogenic enzyme CYP17 is responsible for catalyzing

119 ty of them are differentiated overexpressing steroidogenic enzyme CYP17, a theca cell-specific marker

120 fied enzymes demonstrated involvement of the steroidogenic enzyme cytochrome P450scc (CYP11A1) as wel

121 Cytochrome P450c17, a steroidogenic enzyme encoded by the CYP17A1 gene, cataly

122 ases the mRNA and protein levels of multiple steroidogenic enzyme genes.

123 ralateral slices were treated with steroids, steroidogenic enzyme inhibitors or gonadal tissue itself

124 FSH induction of select steroidogenic enzyme mRNAs, including Cyp19a1, is enhanc

125 levels and enzymatic activity of CYP11A1, a steroidogenic enzyme regulating CD8(+) T-cell conversion

126 ehydrogenase type IV (HSD17B4), coding for a steroidogenic enzyme that converts estradiol (E2) into a

127 The aberrant expression of the steroidogenic enzyme transcripts was detected in CTCs fr

128 Steroidogenic enzyme transcripts were evaluated by quant

129 (4)-abiraterone (D4A), which blocks multiple steroidogenic enzymes and antagonizes the androgen recep

130 s were investigated for mRNA and protein for steroidogenic enzymes and for endogenous synthesis of te

131 Expression of steroidogenic enzymes and GC synthesis in ex vivo organ

132 ortical zonation and defective expression of steroidogenic enzymes as well as renal histology in keep

133 In contrast, the steroidogenic enzymes CYP11A1 and CYP11B1 involved in gl

134 h concomitant reduction in expression of the steroidogenic enzymes CYP11A1, CYP17A1 and HSD17B3, and

135 for Leydig cell maturation and regulation of steroidogenic enzymes in adulthood.

136 ted androgen levels and transcripts encoding steroidogenic enzymes in benign prostate tissue, untreat

137 lism, or altered expression or activities of steroidogenic enzymes in female Cyp2j5 (-/-) mice, but t

138 its effect on the expression of a number of steroidogenic enzymes in the ERbeta ligand metabolic pat

139 ta(4) isomerases (3beta-HSDs), which are key steroidogenic enzymes in vertebrates, and is exclusively

140 Targeted therapy through the inhibition of steroidogenic enzymes may pose an attractive alternative

141 Although the lung expresses all steroidogenic enzymes necessary for de novo synthesis of

142 These steroidogenic enzymes represent targets for complete sup

143 Steroidogenic enzymes required for androgen synthesis fr

144 Mouse lung tissue was found to express steroidogenic enzymes required for the synthesis of cort

145 led that molluscs do not possess many of the steroidogenic enzymes required to make testosterone, nor

146 One of the crucial steroidogenic enzymes, AKR1C3, was significantly elevate

147 he N-terminal TM-helix residues of two human steroidogenic enzymes, CYP 17A1 and CYP 19A1, that are m

148 cloning fragments of the genes encoding two steroidogenic enzymes, CYP17 and CYP19, and examining th

149 CYP2C19, CYP2D6, and CYP3A4 and the crucial steroidogenic enzymes, CYP17 and CYP19.

150 and/or transcriptional repression of several steroidogenic enzymes, in combination with GnRH analogs

151 higher transcript levels for AR and several steroidogenic enzymes, including SRD5A1, SRD5A3, and AKR

152 ases displayed alterations in genes encoding steroidogenic enzymes, including up-regulated expression

153 ition of PDE8s cause increased expression of steroidogenic enzymes.

154 ross all hormones on this latent generalized steroidogenic factor (Cohen's d=0.37, P=0.0009) and this

155 tiation can be replaced by its mouse homolog steroidogenic factor 1 (mSF-1).

156 The elevated level of Steroidogenic Factor 1 (Nr5a1, Sf-1) expression in the m

157 ment, expression of Cyp26b1 is maintained by Steroidogenic Factor 1 (SF-1) and Sex-Determining Region

158 ysiological approaches, we first reveal that steroidogenic factor 1 (SF-1) green fluorescent protein

159 Steroidogenic factor 1 (SF-1) is a transcription factor

160 Steroidogenic factor 1 (SF-1) is an orphan nuclear recep

161 The nuclear receptor steroidogenic factor 1 (SF-1) is essential for adrenal d

162 The nuclear receptor steroidogenic factor 1 (SF-1) is essential for steroidog

163 The transcription factor steroidogenic factor 1 (SF-1) is exclusively expressed i

164 In the central nervous system, steroidogenic factor 1 (SF-1) is required for terminal d

165 We found that mice lacking FOXO1 in steroidogenic factor 1 (SF-1) neurons of the VMH are lea

166 The orphan nuclear receptor steroidogenic factor 1 (SF-1) regulates the differentiat

167 dent on the master transcriptional regulator Steroidogenic Factor 1 (SF-1), and zG-specific Sf-1 dele

168 The steroidogenic factor 1 (SF-1, also known as NR5A1) is a

169 The transcription factor steroidogenic factor 1 (SF-1; also known as NR5A1) is a

170 iver receptor homologue 1 (LRH-1; NR5A2) and steroidogenic factor 1 (SF-1; NR5A1) have therapeutic po

171 including the constitutively active receptor steroidogenic factor 1 (SF-1; NR5A1), is proposed to rep

172 romoting the binding of the nuclear receptor steroidogenic factor 1 (SF1) (Ad4BP, NR5A1) to the promo

173 lective activation of VMH neurons expressing steroidogenic factor 1 (SF1) rapidly inhibits food intak

174 AMH promoter contains two binding sites for steroidogenic factor 1 (SF1), one at -102 and the other

175 pped to the proximal Lhb promoter containing steroidogenic factor 1 (SF1), pituitary homeobox 1 (PTX1

176 vestigate this, we optogenetically activated steroidogenic factor 1 (SF1)-expressing neurons in the d

177 ocortin (POMC)-, single-minded 1 (Sim1)-, or steroidogenic factor 1 (SF1)-expressing neurons in the h

178 , we ectopically activated the Hh pathway in Steroidogenic factor 1 (SF1)-positive somatic cell precu

179 essing the VMH-specific transcription factor steroidogenic factor 1 (SF1).

180 ncer in mice, and that it does so along with steroidogenic factor 1 (SF1, encoded by the gene Nr5a1 (

181 The nuclear receptor steroidogenic factor 1 (Sf1, Nr5a1) is essential for adr

182 The nuclear receptor steroidogenic factor 1 (Sf1, Nr5a1, Ad4bp) is crucial fo

183 The vertebrate nuclear hormone receptor steroidogenic factor 1 (SF1; NR5A1) controls reproductiv

184 significance of COUP-TFII expression in the steroidogenic factor 1 neurons, we generated hypothalami

185 to a subpopulation of neurons expressing the steroidogenic factor 1 transcription factor, known to pl

186 , neuropeptide Y/agouti-related peptide, and steroidogenic factor 1), those of neurons derived from t

187 t of steroidogenic acute regulatory protein, steroidogenic factor 1, and dosage-sensitive sex reversa

188 e in steroidogenic acute regulatory protein, steroidogenic factor 1, and melanocortin type 2 receptor

189 one acetylation, sphingosine is a ligand for steroidogenic factor 1, and nuclear accumulation of cera

190 h) signaling is responsible for transforming steroidogenic factor 1-positive (SF1(+)) progenitors int

191 Steroidogenic factor SF-1, a constitutively active nucle

192 alysis confirmed that one generalized latent steroidogenic factor was driving much of the variation i

193 s show morphofunctional features and adrenal steroidogenic factor, steroid acute regulatory, cytochro

194 Steroidogenic factor-1 (known as NR5A1) is a key regulat

195 signal, cAMP and the orphan nuclear receptor steroidogenic factor-1 (NR5A1).

196 sequences for the orphan nuclear receptors, steroidogenic factor-1 (or NR5A1), and fetoprotein trans

197 Steroidogenic factor-1 (SF-1) and liver receptor homolog

198 rat LC relates inversely to LC expression of steroidogenic factor-1 (SF-1)-dependent genes (StAR, Cyp

199 ceptors liver receptor homolog-1 (LRH-1) and steroidogenic factor-1 (SF-1).

200 (NR5A), liver receptor homolog-1 (LRH-1) and steroidogenic factor-1 (SF-1).

201 The nuclear receptor steroidogenic factor-1 (SF-1, NR5A1) is a key regulator

202 nt of VMH efferent projections, as marked by steroidogenic factor-1 (SF-1; NR5A1).

203 sed the promoter that controls expression of Steroidogenic Factor-1 (SF1) to drive Cre-recombinase-me

204 r (GHR) either in leptin receptor (LepR)- or steroidogenic factor-1 (SF1)-expressing cells were studi

205 depolarizes and increases the firing rate of steroidogenic factor-1 (SF1)-positive neurons in the VMH

206 Because steroidogenic factor-1 and Amh are important for proper

207 ontrol the ability of the protein to bind to steroidogenic factor-1 and the coactivator GCN5 (general

208 To target VMH MC3R expression, we used the steroidogenic factor-1 Cre transgenic mouse.

209 elopment and has been shown to interact with steroidogenic factor-1 in mammals, leading to the suppre

210 CYP17 gene by periodically interacting with steroidogenic factor-1 in response to ACTH signaling.

211 ediated through functional interactions with steroidogenic factor-1 that involve four acidic residues

212 Here, the crystal structures of human NR5A1 (steroidogenic factor-1, SF-1) ligand binding domain (LBD

213 Steroidogenic factor-1-expressing (SF-1-expressing) neur

214 eurons that express the transcription factor steroidogenic-factor 1 (VMN(SF1) neurons) blocks recover

215 Because the expression levels of steroidogenic factors are low and constant over time in

216 hat are noted prior to molecular evidence of steroidogenic failure.

217 rine regulatory role to modulate Leydig cell steroidogenic function.

218 nal morphology that was characterized by non-steroidogenic GATA4- and Gli1-positive cells within the

219 A1 [ABCA1], apoE, SREBP-1c) while preventing steroidogenic gene (StAR) expression.

220 ted germ cell (MNG) induction and suppressed steroidogenic gene expression and testosterone productio

221 sed to identify microRNAs (miRNAs) affecting steroidogenic gene expression under hypoxia.

222 nt of pituitary regulation via modulation of steroidogenic gene expression, and (ii) the role of lept

223 duction but were resistant to suppression of steroidogenic gene expression.

224 sex steroid synthesis by acting directly on steroidogenic gene expression.

225 us Dax-1 downregulates the expression of the steroidogenic gene products CYP11A1 and StAR in both H29

226 The expression of the steroidogenic gene products steroidogenic acute regulato

227 eroidogenic factor 1 (SF-1) is essential for steroidogenic gene transcription.

228 ells resulted in the downregulation of seven steroidogenic genes and one of these, CYP19A1 (aromatase

229 ist increases expression of LRH-1-controlled steroidogenic genes and promotes anti-inflammatory gene

230 hLLCs expressed all steroidogenic genes and proteins important for T biosynt

231 iation-inducing factors in vitro upregulated steroidogenic genes but did not fully induce LC differen

232 that SF1 is a regulator of the expression of steroidogenic genes in all three organs.

233 day 40 pc, followed by initiation of AMH and steroidogenic genes required for androgen production at

234 ted kinase (ERK)1/2, increased expression of steroidogenic genes, and increased neutral lipid storage

235 he SF1 R103Q mutation impaired activation of steroidogenic genes, without affecting synergistic SF-1

236 nd coactivator proteins with the promoter of steroidogenic genes.

237 SF-1 is a key transcription factor for all steroidogenic genes.

238 SPH, increases the transcription of multiple steroidogenic genes.

239 e mRNA expression of CYP17 and several other steroidogenic genes.

240 creased expression of StAR and several other steroidogenic genes.

241 se line we identify and characterize de novo steroidogenic immune cells, defining the global gene exp

242 ely achieved clinical remission, inferring a steroidogenic-independent and MC1R-dispensable anti-prot

243 coelomic epithelium contributes only to non-steroidogenic interstitial cells.

244 e to the adult seminiferous tubules, whereas steroidogenic Leydig cells and other less well character

245 common mechanism in the control of multiple steroidogenic lineages.

246 hypothesized that LDs are a major feature of steroidogenic luteal cells and store cholesteryl esters.

247 Lipid droplets in steroidogenic luteal cells store cholesterol in the form

248 as an important target downstream of PKA in steroidogenic luteal cells.

249 tein S6 kinase 1 (S6K1) signaling pathway in steroidogenic luteal cells.

250 the stimulation of steroid formation in both steroidogenic MA-10 and non-steroidogenic COS-F2-130 cel

251 In the hCG-dependent steroidogenic MA-10 mouse Leydig cell line, the 14-3-3ga

252 Direct estrogenic, androgenic, or steroidogenic mechanisms are unlikely for NAs based on t

253 ngly associated with distinct differences in steroidogenic melanocortin 2 receptor (MC2R) mRNA expres

254 ng adrenocorticotropic hormone (ACTH) or non-steroidogenic melanocortin peptides attenuates proteinur

255 renal gland is a multiendocrine organ with a steroidogenic mesenchymal cortex and an inner catecholam

256 The results indicate that monitoring steroidogenic metabolites in patients with PCa may provi

257 tivity in transfected cells or with isolated steroidogenic mitochondria, nevertheless, can bind as mu

258 motions of lipid droplet (LD) organelles in steroidogenic mouse adrenal cortical (Y-1) cells with CA

259 tely ablated progesterone conversion in both steroidogenic mouse Leydig MA-10 and human adrenal NCI c

260 tosterone ratio, and decreased expression of steroidogenic mRNAs, appropriately modeling primary test

261 ger-like protrusions, and a misexpression of steroidogenic or FLC- and ALC-specific genes.

262 The brain is a steroidogenic organ and is thus dependent on estrogen fo

263 e evolutionarily conserved Hh pathway to the steroidogenic organs, demonstrating how Hh signaling can

264 yed from peripheral tissues to the liver and steroidogenic organs.

265 stimulating hormone (NDP-MSH), a potent non-steroidogenic pan-melanocortin receptor agonist, on the

266 Many key factors within the adrenal steroidogenic pathway have been identified and studied,

267 is the first and rate-limiting enzyme in the steroidogenic pathway, converting cholesterol to pregnen

268 ovel agents capable of inhibiting intracrine steroidogenic pathways within the prostate tumor microen

269 In addition to metabolic and steroidogenic pathways, RNA-sequencing analysis revealed

270 The non-steroidogenic progenitor cells retain their undifferenti

271 Inhibition of calcium signaling in the steroidogenic prothoracic gland results in the accumulat

272 Steroidogenic rates are also critically dependent on the

273 ntally in the rat, our results show that the steroidogenic regulatory network architecture is suffici

274 eveloped a mathematical model of the adrenal steroidogenic regulatory network that accounts for key r

275 r steroidogenesis), and a failure to mount a steroidogenic response to ACTH.

276 The acute steroidogenic response, which produces steroids in respo

277 P2 protein expression and partially restored steroidogenic responses, confirming the requirement of S

278 In primary cultures of steroidogenic small luteal cells (SLCs), LH, and forskol

279 In this study, we have generated steroidogenic-specific Cre-expressing mice to lineage ma

280 mutagenesis, we have provided evidence that steroidogenic SR-BI is a direct target of miRNA-125a and

281 both miRNA-125a and miRNA-455, by targeting steroidogenic SR-BI, negatively regulate selective HDL C

282 ted mice, S-norfluoxetine, a selective brain steroidogenic stimulant (SBSS), in doses (0.45-1.8 mumol

283 Steroidogenic stimulation of mouse MA-10 Leydig cells wi

284 Tcf21-expressing cells give rise only to non-steroidogenic stromal adrenocortical cells, which also e

285 Steroidogenic T cells dysregulate anti-tumor immunity, a

286 idogenesis in CD8(+) T cells, a nonclassical steroidogenic tissue, to a proallergic differentiation p

287 yzes the hydrolysis of cholesteryl esters in steroidogenic tissues and, thus, facilitates cholesterol

288 PDE11A is highly expressed in endocrine steroidogenic tissues, especially the testis, and mice w

289 one precursor that is synthesized in various steroidogenic tissues, in the brain, and in lymphocytes.

290 and pathophysiological processes in several steroidogenic tissues, including the testis, ovary, adre

291 rt into mitochondria, is highly expressed in steroidogenic tissues, metastatic cancer, and inflammato

292 erol is transported into the mitochondria of steroidogenic tissues, the first steroid, pregnenolone,

293 In steroidogenic tissues, upon hormone stimulation, there i

294 nucleotides by phosphodiesterases (PDEs) in steroidogenic tissues.

295 n could potentially influence cancer risk in steroidogenic tissues.

296 l for formation, development and function of steroidogenic tissues.

297 tochondrial cholesterol transport complex in steroidogenic tissues.

298 oncerning mechanisms of their secretion from steroidogenic tissues.

299 ion of SR-BI and miRNA-125a and miRNA-455 in steroidogenic tissues/cells and that both miRNA-125a and

300 P450, subfamily XVII (CYP17A1) and other key steroidogenic transcripts including steroidogenic acute