ライフサイエンスコーパス: steroidogenic factor 1

1 n the adrenal strategy and is independent of steroidogenic factor-1.

2 StAR transcription by lipoproteins requires steroidogenic factor-1.

3 Cotransfection of C/EBPalpha or -beta and steroidogenic factor 1, a transcription factor required

4 Steroidogenic factor-1/adrenal 4-binding protein (SF-1/A

5 Leydig cell differentiation by up-regulating Steroidogenic Factor 1 and P450 Side Chain Cleavage enzy

6 Because steroidogenic factor-1 and Amh are important for proper

7 ontrol the ability of the protein to bind to steroidogenic factor-1 and the coactivator GCN5 (general

8 identified through its interaction with SF1 (steroidogenic factor 1) and has been demonstrated to be

9 the Wnt signaling pathway, beta-catenin and steroidogenic factor 1, and chromatin immunoprecipitatio

10 t of steroidogenic acute regulatory protein, steroidogenic factor 1, and dosage-sensitive sex reversa

11 e in steroidogenic acute regulatory protein, steroidogenic factor 1, and melanocortin type 2 receptor

12 one acetylation, sphingosine is a ligand for steroidogenic factor 1, and nuclear accumulation of cera

13 pting recruitment of beta-catenin at or near steroidogenic factor 1 binding sites present in multiple

14 al and depend on the orphan nuclear receptor steroidogenic factor-1, but the placental strategy for t

15 To target VMH MC3R expression, we used the steroidogenic factor-1 Cre transgenic mouse.

16 Steroidogenic factor-1-expressing (SF-1-expressing) neur

17 mbryonic invalidation of the Prkar1a gene in steroidogenic factor-1-expressing cells leads to the dev

18 abundance of mRNA for P450scc, P450c17, and steroidogenic factor 1 in SEB-1 sebocytes and sebaceous

19 more abundant than mRNA for both P450c17 and steroidogenic factor 1 in sebaceous glands and SEB-1 cel

20 elopment and has been shown to interact with steroidogenic factor-1 in mammals, leading to the suppre

21 CYP17 gene by periodically interacting with steroidogenic factor-1 in response to ACTH signaling.

22 Steroidogenic factor-1 (known as NR5A1) is a key regulat

23 opulation sharing a community of origin with steroidogenic factor-1 lineage.

24 arbon receptor (AhR)-binding sites and three steroidogenic factor-1 motifs that are associated with c

25 tiation can be replaced by its mouse homolog steroidogenic factor 1 (mSF-1).

26 significance of COUP-TFII expression in the steroidogenic factor 1 neurons, we generated hypothalami

27 The elevated level of Steroidogenic Factor 1 (Nr5a1, Sf-1) expression in the m

28 Steroidogenic factor-1 (NR5A1) plays a central role in t

29 signal, cAMP and the orphan nuclear receptor steroidogenic factor-1 (NR5A1).

30 sequences for the orphan nuclear receptors, steroidogenic factor-1 (or NR5A1), and fetoprotein trans

31 oxin reductase, and the transcription factor steroidogenic factor 1, P450scc converts cholesterol to

32 h) signaling is responsible for transforming steroidogenic factor 1-positive (SF1(+)) progenitors int

33 ns expressing pro-opiomelanocortin (POMC) or steroidogenic factor 1 (SF-1) alters feeding behavior an

34 lear receptor NR5A subfamily, which includes steroidogenic factor 1 (SF-1) and liver receptor homolog

35 Here, we report that steroidogenic factor 1 (SF-1) and liver receptor homolog

36 ment, expression of Cyp26b1 is maintained by Steroidogenic Factor 1 (SF-1) and Sex-Determining Region

37 Products of steroidogenic factor 1 (SF-1) and Wilms' tumor 1 (WT1) g

38 It contains a steroidogenic factor 1 (SF-1) element (-668) that binds

39 Cooperative participation of multiple steroidogenic factor 1 (SF-1) elements with the downstre

40 ysiological approaches, we first reveal that steroidogenic factor 1 (SF-1) green fluorescent protein

41 The orphan nuclear receptor steroidogenic factor 1 (SF-1) is a critical developmenta

42 Steroidogenic factor 1 (SF-1) is a transcription factor

43 Steroidogenic factor 1 (SF-1) is an orphan nuclear recep

44 Steroidogenic factor 1 (SF-1) is an orphan nuclear recep

45 Steroidogenic factor 1 (SF-1) is an orphan nuclear recep

46 The nuclear receptor steroidogenic factor 1 (SF-1) is essential for adrenal d

47 The nuclear receptor steroidogenic factor 1 (SF-1) is essential for steroidog

48 The transcription factor steroidogenic factor 1 (SF-1) is exclusively expressed i

49 The orphan nuclear receptor steroidogenic factor 1 (SF-1) is expressed in the adrena

50 In the central nervous system, steroidogenic factor 1 (SF-1) is required for terminal d

51 regulated, we monitored their expression in steroidogenic factor 1 (SF-1) knock-out mice.

52 We found that mice lacking FOXO1 in steroidogenic factor 1 (SF-1) neurons of the VMH are lea

53 The orphan nuclear receptor steroidogenic factor 1 (SF-1) regulates the differentiat

54 sponsiveness to 8-Br-cAMP in the presence of steroidogenic factor 1 (SF-1) when placed behind a minim

55 aled two motifs resembling binding sites for steroidogenic factor 1 (SF-1), a member of the orphan nu

56 Steroidogenic factor 1 (SF-1), an orphan member of the i

57 dent on the master transcriptional regulator Steroidogenic Factor 1 (SF-1), and zG-specific Sf-1 dele

58 as that of another orphan nuclear receptor, steroidogenic factor 1 (SF-1), that is required for deve

59 form the VMH is the orphan nuclear receptor, steroidogenic factor 1 (SF-1), which can be detected in

60 nteractions with the orphan nuclear receptor steroidogenic factor 1 (SF-1).

61 it is regulated by the transcription factor, steroidogenic factor 1 (SF-1).

62 The steroidogenic factor 1 (SF-1, also known as NR5A1) is a

63 toire by examining beta-catenin (CTNNB1) and steroidogenic factor 1 (SF-1, NR5A1), a transcription fa

64 restricted expression is driven, in part, by steroidogenic factor 1 (SF-1, NR5A1), which stimulates T

65 The transcription factor steroidogenic factor 1 (SF-1; also known as NR5A1) is a

66 Steroidogenic factor 1 (SF-1; Nr5a1) and liver receptor

67 iver receptor homologue 1 (LRH-1; NR5A2) and steroidogenic factor 1 (SF-1; NR5A1) have therapeutic po

68 including the constitutively active receptor steroidogenic factor 1 (SF-1; NR5A1), is proposed to rep

69 Two transcription factors, steroidogenic factor-1 (SF-1) and early growth response-

70 Steroidogenic factor-1 (SF-1) and liver receptor homolog

71 inding sites for the orphan nuclear receptor steroidogenic factor-1 (SF-1) are occupied in vitro by u

72 Analysis of a patient heterozygous for the steroidogenic factor-1 (SF-1) gene suggested that reduce

73 The nuclear receptor steroidogenic factor-1 (SF-1) has been implicated as a d

74 a regulation of the phosphorylation state of steroidogenic factor-1 (SF-1) in mediating ACTH/cAMP-dep

75 Steroidogenic factor-1 (SF-1) is a phospholipid-sensing

76 Steroidogenic factor-1 (SF-1) is an orphan nuclear recep

77 hypoglycemic stimulation of GABAergic neuron steroidogenic factor-1 (SF-1) mRNA.

78 conservation of a sequence homologous to the steroidogenic factor-1 (SF-1) regulatory element of cyto

79 Among these, the orphan receptor steroidogenic factor-1 (SF-1) was found to potently tran

80 ear receptor that represses transcription by steroidogenic factor-1 (SF-1), a factor that regulates e

81 he LHbeta gene in vitro through synergy with steroidogenic factor-1 (SF-1), a protein required for go

82 have implicated the orphan nuclear receptor, steroidogenic factor-1 (SF-1), and the early growth resp

83 clin D2 as well as inhibin-alpha, aromatase, steroidogenic factor-1 (SF-1), cholesterol side chain (S

84 The orphan nuclear receptor, steroidogenic factor-1 (SF-1), is expressed in the pitui

85 trophoretic mobility-shift analyses a distal steroidogenic factor-1 (SF-1)-binding site that is essen

86 rat LC relates inversely to LC expression of steroidogenic factor-1 (SF-1)-dependent genes (StAR, Cyp

87 2(R)-OHC), 25-OHC, and 27-OHC each increased steroidogenic factor-1 (SF-1)-mediated StAR gene transac

88 red for synergistic activation by NGFI-A and steroidogenic factor-1 (SF-1).

89 ceptors liver receptor homolog-1 (LRH-1) and steroidogenic factor-1 (SF-1).

90 (NR5A), liver receptor homolog-1 (LRH-1) and steroidogenic factor-1 (SF-1).

91 Here, we demonstrate that a conserved steroidogenic factor-1 (SF-1)/NR5A1 binding enhancer is

92 The nuclear receptor steroidogenic factor-1 (SF-1, NR5A1) is a key regulator

93 nt of VMH efferent projections, as marked by steroidogenic factor-1 (SF-1; NR5A1).

94 Here, the crystal structures of human NR5A1 (steroidogenic factor-1, SF-1) ligand binding domain (LBD

95 romoting the binding of the nuclear receptor steroidogenic factor 1 (SF1) (Ad4BP, NR5A1) to the promo

96 latory protein 2) was identified using mouse steroidogenic factor 1 (SF1) as bait in a yeast two-hybr

97 out mice lacking the orphan nuclear receptor steroidogenic factor 1 (SF1) exhibit a complex endocrine

98 d ERK2 signaling in neurons that express the steroidogenic factor 1 (SF1) in the VMH in energy homeos

99 eutherian mammals, such as mice and humans, steroidogenic factor 1 (SF1) plays important roles in th

100 lective activation of VMH neurons expressing steroidogenic factor 1 (SF1) rapidly inhibits food intak

101 The expression of steroidogenic factor 1 (Sf1), a nuclear receptor essenti

102 AMH promoter contains two binding sites for steroidogenic factor 1 (SF1), one at -102 and the other

103 pped to the proximal Lhb promoter containing steroidogenic factor 1 (SF1), pituitary homeobox 1 (PTX1

104 Mutations were introduced into conserved steroidogenic factor 1 (SF1)- and SOX9-binding sites wit

105 vestigate this, we optogenetically activated steroidogenic factor 1 (SF1)-expressing neurons in the d

106 ocortin (POMC)-, single-minded 1 (Sim1)-, or steroidogenic factor 1 (SF1)-expressing neurons in the h

107 , we ectopically activated the Hh pathway in Steroidogenic factor 1 (SF1)-positive somatic cell precu

108 essing the VMH-specific transcription factor steroidogenic factor 1 (SF1).

109 ncer in mice, and that it does so along with steroidogenic factor 1 (SF1, encoded by the gene Nr5a1 (

110 The nuclear receptor steroidogenic factor 1 (Sf1, Nr5a1) is essential for adr

111 The nuclear receptor steroidogenic factor 1 (Sf1, Nr5a1, Ad4bp) is crucial fo

112 The vertebrate nuclear hormone receptor steroidogenic factor 1 (SF1; NR5A1) controls reproductiv

113 sed the promoter that controls expression of Steroidogenic Factor-1 (SF1) to drive Cre-recombinase-me

114 r (GHR) either in leptin receptor (LepR)- or steroidogenic factor-1 (SF1)-expressing cells were studi

115 depolarizes and increases the firing rate of steroidogenic factor-1 (SF1)-positive neurons in the VMH

116 ption from a -966 StAR promoter in which the steroidogenic factor-1 site at -135 was abolished, indic

117 ediated through functional interactions with steroidogenic factor-1 that involve four acidic residues

118 , neuropeptide Y/agouti-related peptide, and steroidogenic factor 1), those of neurons derived from t

119 to a subpopulation of neurons expressing the steroidogenic factor 1 transcription factor, known to pl

120 eurons that express the transcription factor steroidogenic-factor 1 (VMN(SF1) neurons) blocks recover

121 ytochrome P450 17-hydroxylase (P450c17), and steroidogenic factor 1 was documented in human facial sk