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1 ngivalis 381 renders this strain more immune-stimulatory.
2 under certain conditions IL-10 can be immune stimulatory.
3 st stimulatory and B. licheniformis PGA most stimulatory.
5 of frameshifting is achieved by the combined stimulatory action of a "slippery" sequence, an mRNA pse
6 y cell signaling pathway that determines the stimulatory action of ethanol and identifies HSP-16.48 a
7 rther characterization of Hld suggests GLP-1 stimulatory action of Hld occurs via calcium signaling.
8 r findings suggest that TCF7L2 regulates the stimulatory actions of nicotine on a habenula-pancreas a
9 jor compound of Gram-negative bacteria, with stimulatory activities in some cancer types, but has not
11 out to identify microbial strains with GLP-1 stimulatory activity as potential metabolic disease ther
13 as being of shorter duration, thalamic post-stimulatory activity emerged following a longer latency
14 ng end of polymeric compounds, to the coffee stimulatory activity in cells mediating innate and acqui
15 bsence of an explicit behavioural task, post-stimulatory activity in sensory cortex may play a functi
18 latency than in cortex, indicating that post-stimulatory activity may be generated within auditory co
21 observed a strong correlation between the PP-stimulatory activity of STN1 variants and their abilitie
22 kDa membranes, has previously shown in vitro stimulatory activity on BALB/c mice spleen B lymphocytes
24 A TFIIS mutant variant (TFIISmut) lacks the stimulatory activity to promote RNA cleavage, but instea
26 h Staphylococcus sciuri, which has high Nod2-stimulatory activity, was sufficient to promote robust C
32 s the possible use of gamma irradiation as a stimulatory agent to raise the nutritive value and antio
35 the PGAs, with B. anthracis PGA being least stimulatory and B. licheniformis PGA most stimulatory.
37 ells, T-cell-receptor ligation-along with co-stimulatory and cytokine signals-induces a glycolytic an
38 hat the effects of developmental hypoxia are stimulatory and directed; (2) the up-regulated proteins
40 lthy immune system results from a balance of stimulatory and inhibitory pathways that allow effective
41 T cells co-exist in human cancers and share stimulatory and inhibitory pathways, immunotherapeutic s
42 rious signaling molecules, and supported the stimulatory and inhibitory roles of Shh and Bmp, respect
43 erential sensitivities of Kv7.4 and Kv7.5 to stimulatory and inhibitory signaling and reveal structur
44 g inputs, coreceptors can engage concomitant stimulatory and inhibitory signaling events, which act t
45 es that seek to modulate the balance between stimulatory and inhibitory signals to lead to favorable
46 ese functions are determined by a balance of stimulatory and inhibitory signals, the role of macropha
50 , the fusion proteins showed stronger T cell-stimulatory and reduced IgE-binding capacity and induced
51 yte calcium signaling also altered the acute stimulatory and sedative-hypnotic effects of ethanol.
52 IT cell in complex with MR1 bound to the non-stimulatory and stimulatory compounds showed distinct li
53 erotic lesions and produce less hypocretin-a stimulatory and wake-promoting neuropeptide-in the later
54 In this study, we report that these highly stimulatory antigen-presenting cells also express enhanc
56 be quantitative approaches used to infer the stimulatory capacity of a given pathogen nucleic acid sp
61 modulate MHC binding and selectivity, T cell stimulatory capacity, and susceptibility to processing b
64 of N-WASP reduces the diffusivity of CD19, a stimulatory co-receptor, but not that of FcgammaRIIB, an
66 ex with MR1 bound to the non-stimulatory and stimulatory compounds showed distinct ligand orientation
69 ne transfer that can be either inhibitory or stimulatory, connections between CRISPR-Cas and DNA repa
70 ion, suggesting the importance of the immune-stimulatory context for the induction of this B cell phe
72 and DCD rats were pretreated with vehicle or stimulatory CpG ODN (beating heart control and DCD stimu
73 In this regard, NFAT5 upregulated the Th1-stimulatory cytokine IL-12 in classically activated macr
74 n of TLR7 leads to the production of several stimulatory cytokines, including type I interferons (IFN
76 ifted by about 6 months, and we suggest that stimulatory day lengths and the proliferation of nesting
78 domain with an IGK CAR containing a CD3zeta stimulatory domain, maintained the target specificity of
81 low-up showed no in vitro reactivity against stimulatory donor blood cells on day 360, whereas reacti
83 (~60 nanomolar), whereas the potency of its stimulatory effect is >100 fold higher, than reported, a
84 nction of CtIP to promote MRN, also the DNA2 stimulatory effect is facilitated by CtIP phosphorylatio
87 n intake affect the fasted state of, and the stimulatory effect of a protein-rich meal on, protein ab
89 ted, and expressed HIV-1 Vpr, antagonize the stimulatory effect of a variety of pathogen associated m
92 d evidence that Gnb5 knockout eliminated the stimulatory effect of cell adhesion on Oxo-M-stimulated
93 RK channel activation, tempers the locomotor stimulatory effect of cocaine while also modulating the
97 o the culture in FBS appeared to inhibit the stimulatory effect of FBS on ILY, MsgA, and NanA, althou
99 n in vitro, and IP deficiency diminished the stimulatory effect of indomethacin on STAT6-independent
101 gr1 is both necessary and sufficient for the stimulatory effect of insulin on leptin transcription.
103 bone healing, and we previously reported the stimulatory effect of mechanical loading in vessel remod
104 ATP into a peripheral nerve might mimic the stimulatory effect of nerve injury on the regenerative s
107 -than-expected rate, possibly explained by a stimulatory effect of plasma heparin on antithrombin.
108 ion, the molecular mechanisms underlying the stimulatory effect of platelets on leukocyte transendoth
111 tion site as well as characterization of the stimulatory effect of Tat on P-TEFb catalytic efficiency
112 NBCe1-A can be explained by an unanticipated stimulatory effect of the CAs on an endogenous Na-H exch
113 duce the inhibitory effect of Ca(2+) and the stimulatory effect of thrombomodulin on the rate of zymo
116 nolasiban treatment alone has no significant stimulatory effect on both the myometrium and amnion.
120 metformin and then treated with LCA lost all stimulatory effect on endothelial cell proliferation and
124 entration >500 p.p.m. triggered a pronounced stimulatory effect on vagal bronchopulmonary C-fibres in
125 duced action potential amplitude exceeds the stimulatory effect resulting from the increased action p
131 However, its expression has a detectable stimulatory effect(s) on CHIKV replication, and Fhl1 kno
132 hat the PKC phosphorylation of Nem1 exerts a stimulatory effect, but the phosphorylation of Spo7 has
133 pulse (an asymmetrical bipolar pulse) had a stimulatory effect, evoking larger Ca(2+) responses than
135 l stimulator of exosome secretion, and these stimulatory effects are, in part, mediated by intracellu
141 nflammatory macrophages, as suggested by the stimulatory effects of heterologously expressed guanine
142 a-mediated proinflammatory responses and the stimulatory effects of IL-1beta on house dust mite (HDM)
143 uclear cells by RNA sequencing confirmed the stimulatory effects of NETs, demonstrated NET-induced en
144 f the alpha3beta4 nAChR subtype, reduced the stimulatory effects of nicotine on habenular neurons, an
145 uggest that alpha3beta4* nAChRs regulate the stimulatory effects of nicotine on the mHb-IPn circuit a
148 would be higher in heated mesocosms; (b) the stimulatory effects of warming on cyanobacterial abundan
150 ified the receptors that mediate glutamate's stimulatory effects on the counterregulatory responses,
151 ings support the hypothesis that melatonin's stimulatory effects on vocal-acoustic mechanisms in mids
153 Comparison of the HAX-1 deletion-induced stimulatory effects with those elicited by PLN ablation
156 expression data with the candidate cargo in stimulatory EVs, delineated the potentially targeted bio
157 ilical cord blood-derived CD34(+) HSPCs with stimulatory EVs-altered HSPC transcriptome, including ge
161 acea isolates have been shown to produce two stimulatory factors that can induce tubeworm and coral m
163 9.361 injection also decreased expression of stimulatory Fcgamma receptors, especially FcgammaRIII, a
165 n platform, benefiting from intrinsic immuno-stimulatory features while retaining excellent safety pr
167 ontology enrichment analysis revealed immune-stimulatory function as the most significant enriched bi
168 support a substantially revised model for co-stimulatory function in the primary GC response, with cr
171 ession of known NR4A3 target genes and has a stimulatory functional effect on cell proliferation.
176 2AR) bound to the G protein adenylyl cyclase stimulatory G protein (Gs) captured the complex in a nuc
177 partly identical to the alpha-subunit of the stimulatory G protein (Gsalpha), but the cellular action
178 ich is catalyzed by the alpha-subunit of the stimulatory G protein (Gsalpha), controls renin synthesi
182 ction mutations of GNAL, a gene encoding the stimulatory G-protein Galphaolf, which is critical for a
183 oded protein, Galphaolf, an adenylyl-cyclase-stimulatory G-protein highly enriched in striatal projec
184 se 5 (AC5), which is itself regulated by the stimulatory Galphaolf and inhibitory Galphai proteins.
185 rin) to be among the most highly induced IFN stimulatory genes in activated NK cells, correlating wit
186 d from nondiabetic donors, incubation at non-stimulatory glucose concentrations promotes a shift in v
188 ns of Cre-inducible viral vectors containing stimulatory (hM3Dq) or inhibitory (hM4Di) designer recep
189 its catalytic domain and the J-domain of its stimulatory Hsp40 cochaperone, suggest that PfHsp70-x is
191 re about coexpression of both inhibitory and stimulatory immune checkpoints on individual cells withi
192 objective was to assess anti-progression and stimulatory immune response effects among anthocyanins (
193 ASI aims to induce a regulatory, rather than stimulatory, immune response in order to reduce, or prev
194 served residues within its AAD, and that the stimulatory impact of these modifications is required fo
195 detected an increase in the levels of immune stimulatory inflammatory cytokines, for example, IFN-gam
196 both necessary and sufficient to mediate the stimulatory influence of the flora on myeloid cell longe
198 of the lung milieu, converting an effective stimulatory influenza-reactive environment into a suppre
199 mory-type cells that use amplified low-level stimulatory input, and whose loss of negative coregulato
201 that cancer cell expression of the T-cell co-stimulatory ligand CD80 sensitizes murine tumors to a FA
202 found that biophysical properties of the aTM-stimulatory ligand density, stiffness, and ECM proteins-
203 Engagement of the T cell receptor (TCR) by stimulatory ligand results in the rapid formation of mic
205 nessing the tumor's own production of excess stimulatory ligands to deplete adjacent ECs of the capac
208 e arthritis and were treated with either the stimulatory mAb to LAIR-1 or a hamster IgG control.
214 ust one cycle of treatment induces an immune stimulatory microenvironment harboring more tumor infilt
216 T cells to constitutively express the immune-stimulatory molecule CD40 ligand (CD40L) and explored ef
219 migDC2) that similarly upregulate surface co-stimulatory molecules but express pathogen-specific cyto
222 sed to a diverse range of potentially immune-stimulatory molecules including semi-allogeneic antigens
224 everal pathways of regulation of ILC2s by co-stimulatory molecules such as ICOS, regulatory T cells a
225 ent cells secrete proinflammatory and growth-stimulatory molecules, termed the senescence-associated
226 ass II family, cytokines, chemokines, and co-stimulatory molecules, was significantly altered in tumo
228 ibition of RA signaling within TME increases stimulatory monocyte-derived cells, enhances T cell-depe
230 enhanced migration and permeability of tumor-stimulatory myeloid cells, and suppressed EC-mediated st
232 leading to cell-surface expression of immune stimulatory natural killer group 2D (NKG2D) ligands on t
234 upregulates surface expression of the immune stimulatory NK group 2, member D (NKG2D) ligands ULBP2 a
236 ed responses among host genes with predicted stimulatory or inhibitory effects on HIV expression like
238 ding and ultraviolet radiation, resulting in stimulatory or inhibitory signals via plasma membrane nu
239 ha-cells) plays a bidirectional role, either stimulatory or inhibitory, in glucagon secretion dependi
242 ctivation, but it remains unclear whether co-stimulatory pathways also control T cell differentiation
246 tive immaturity, and challenge the view that stimulatory peptides are the ultimate gatekeepers of pub
247 ription factor HSF-1 played in determining a stimulatory phenotype of Caenorhabditis elegans in respo
248 ses could be ascribed to an increased T cell stimulatory phenotype of TORC2(DC-/-) and not to enhance
249 we determine the solubility profile and true stimulatory potency of Vx-770 towards wild-type (WT) and
250 ever, clinical evidence regarding its immune-stimulatory potential in human Crohn's disease remains s
252 OVs is increasingly focused on their immune stimulatory properties, which may work synergistically w
253 ch as competing non-cognate substrates and a stimulatory protein factor DapF, to achieve the differen
254 g, we identified an immune cell-specific, co-stimulatory receptor B7.2 (CD86) as a co-receptor of lym
256 munoglobulin and ITIM domain (TIGIT), the co-stimulatory receptor CD226 and their ligand PVR are alte
260 gG2b mAb that binds both FcgammaRIIB and the stimulatory receptor FcgammaRIII), by actively immunizin
261 se of CD8(+) effector T cells expressing the stimulatory receptor Klrk1/NKG2D, a decrease in CD4(+) C
262 ns were accompanied by reduced expression of stimulatory receptor Ly49D on educated NK cells and incr
263 nversely, expression of the complementary co-stimulatory receptor of TIGIT, CD226 (DNAM-1) was signif
264 hat applied forces increase the lifetimes of stimulatory receptor-ligand bonds (catch-bond behavior).
266 ptors is counterbalanced by expression of co-stimulatory receptors and it is only SIRPalpha(+) cells
267 46, DNAX accessory molecule-1, and NKG2C and stimulatory receptors such as CD2 and CD11c were express
268 dentify that targeting alternative T-cell co-stimulatory receptors, in particular OX-40 and 4-1BB in
269 ity, upregulates the expression of T-cell co-stimulatory receptors, with the inducible co-stimulator
271 between PRR and ELABELA/apelin, the mutually stimulatory relationship between PRR and COX-2/PGE(2) or
272 basal open probability but did not attenuate stimulatory response to beta-adrenergic agonists when re
274 st tested the sensitivity to d-Amphetamine's stimulatory, reward-enhancing, and primary rewarding eff
275 intercellular adhesion molecule 1, and (3) a stimulatory role for thrombin, the thrombospondin-1/CD36
277 ia to test the hypothesis that calcium has a stimulatory role in skeletal muscle mitochondria not app
280 s is tightly regulated by a combinational co-stimulatory signal, and dominance of negative co-stimula
281 human cells, promoting the expression of co-stimulatory signals and the secretion of pro-inflammator
282 o drive NK cell clonal expansion, additional stimulatory signals controlling their proliferation rema
283 The OX40-OX40L pathway provides crucial co-stimulatory signals for CD4 T cell responses, however th
284 ptor 4-1BB and its ligand 4-1BBL provides co-stimulatory signals for T-cell activation and proliferat
285 ed hydrogel is engineered to present the two stimulatory signals required for T-cell activation-terme
288 ciency can vary enormously between different stimulatory structures, but the features that lead to ef
291 receptors (GPCRs) and thus mice lacking the stimulatory subunit of G-protein (Gsalpha) in osteocytes
294 PD-1 showed increased infiltration of immune stimulatory T cells versus either monotherapy treatment
295 g CTD cell surface proteins were more immune-stimulatory than the parental wild-type strains, consist
296 vate the immune system and the generation of stimulatory TSHR Abs in genetically predisposed individu
297 R has opposing effects on BCC carcinogenesis-stimulatory via mutagenesis and inhibitory via productio
299 tagonistic effects on mitochondrial editing: stimulatory, which requires a catalytic glutamate for mo
300 TSPX, truncation of which renders TSPX to be stimulatory while its transposition to the C-terminus of