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1 admission stratum, and 2138 (47%) in the ICU stratum.
2 utions to each country dataset and mortality stratum.
3 e, sparing no nation, ethnicity, or economic stratum.
4 MI reduction, in the full cohort and in each stratum.
5 d ratios (HRs) were calculated for each time stratum.
6 ith radiocontrast administration within each stratum.
7 sidered for those in the low-mortality-score stratum.
8 w-energy context of the enclosing sandy silt stratum.
9 le lightness and body size for each vertical stratum.
10 ntervention did not differ by BMI percentile stratum.
11 ated randomisation list was used within each stratum.
12 s of atherosclerosis in either postmenopause stratum.
13 the estradiol group in either postmenopause stratum.
14 imilar difference was found across each race stratum.
15 muted blocks (block size of six) within each stratum.
16 B radiation) were recorded for each vertical stratum.
17 naptic plasticity adequate for each neuronal stratum.
18 [OAC] treatment recommendation) in each age stratum.
19 domisation with a block size of four in each stratum.
20 g that inequality persists across the social stratum.
21 each point during follow-up and by mortality stratum.
22 admission stratum, and 1547 (84%) in the ICU stratum.
23 ent effect behaves similarly across all risk stratums.
24 es: an upper freshwater-to-moderately saline stratum (0-3 m), an intermediate stratum exhibiting a st
29 Eligible children aged 12 to <18 years (age stratum 1), 2 to <12 years (stratum 2), and >3 months to
30 gible and evaluable patients were accrued to stratum 1, and between Aug 28, 2013, and June 25, 2015,
33 rticipants were included in the HIV-infected stratum (146 [20.5%] were culture positive) and 313 were
34 zation than with medical therapy in the CABG stratum (15.3% vs. 30.3%, p = 0.02), but not in the PCI
35 ore study, 848 (19%) patients were in the ER stratum, 1523 (34%) in the admission stratum, and 2138 (
36 p=0.02), but not in the low-mortality-score stratum (17 [24%] of 72 vs 21 [20%] of 105; adjusted odd
38 o <18 years (age stratum 1), 2 to <12 years (stratum 2), and >3 months to <2 years (stratum 3) had an
39 variable after treatment with HA, whereas in stratum 2, Streptococcus, Veillonella, Rothia, and Granu
40 tion and medical therapy, either in the CABG stratum (26.1% vs. 29.9%, p = 0.41) or in the PCI stratu
41 obial diversity was found to be decreased in stratum 3 (P < 0.05) after treatment with HA compared wi
44 ears (stratum 2), and >3 months to <2 years (stratum 3) had an objectively confirmed diagnosis of VTE
47 was monotherapy in the high-mortality-score stratum (30 [48%] of 63 vs 64 [62%] of 103; adjusted HR
49 halocline (3-3.5 m), and a lower hypersaline stratum (4 m and below) that is euxinic (i.e. anoxic and
50 ients with moderate-to-severe TBI in the ICU stratum, 623 (55%) patients had unfavourable outcome at
51 8) was found in 207 (30%) patients in the ER stratum, 665 (53%) in the admission stratum, and 1547 (8
53 the usual care group in the invasive testing stratum ($8,619 vs. $ 10,734; p < 0.0001), whereas in th
56 SULTSA total of 19 patients were enrolled in stratum A (median age,11 years) and 10 in stratum B (med
57 hs was 40% (95% CI, 22%-73%) for patients in stratum A and 39% (95% CI, 16%-93%) for patients in stra
58 the >/=55-year stratum than in the <55-year stratum, a finding that could be explained by biology, s
60 we introduce a novel similarity measure, the stratum adjusted correlation coefficient (SCC), for quan
61 patients (95% CI, 96%-99%; difference in the stratum-adjusted Mantel-Haenszel proportions of -3.2%; 9
63 oup (relative risk adjusted for birth-weight stratum and center, 1.00; 95% confidence interval [CI],
65 emia peaked at 48% at week 8 in the high PTH stratum and then steadily decreased through month 12.
68 regression models adjusted for sex, weights, stratum, and primary sampling unit were used to analyse
69 lculated for each urologist within each risk stratum, and the association between the physician-level
70 , including uncinate fasciculus and sagittal stratum as a control tract, were registered to the study
76 f two-photon fluorescence lifetime images of stratum basale and stratum granulosum layers of skin.
77 ve care compared with whites in any hospital stratum, but the odds of palliative care for both white
78 Functional groups based on habitat domain (stratum) caught the essential functional differences bet
79 r adjustment for age, gender, socio-economic stratum, city and other IgE levels (adjusted ORs: 2.17;
81 showed that it shrunk the corneocytes in the stratum corneum (p<0.001) and the imaging of the skin ha
82 s of the long periodicity phase (LPP) in the stratum corneum (SC) are studied using bilayer-slab-bila
83 h quantity and spatial distribution of human stratum corneum (SC) lipids from samples collected in vi
84 ges between altered ceramide profiles in the stratum corneum (SC) of patients with atopic dermatitis
86 to puncture the skin, can bypass the skin's stratum corneum (SC) to enter the skin microcirculation
88 iscrete epidermal skin layers, including the stratum corneum (SC), stratum granulosum (SG), stratum b
89 solvents on the outermost layer of skin, the stratum corneum (SC), using polarization transfer solid-
91 ubstantially reduced drug diffusivity in the stratum corneum (the outermost epidermal layer), dominan
92 of interventions with partial removal of the stratum corneum after curettage and microdermabrasion an
94 tion can effectively carry siRNA through the stratum corneum and deposit it at the lower epidermis/up
95 ely, a low permeability of siRNA through the stratum corneum and epidermis has significantly limited
97 e the skin permeation barrier imposed by the stratum corneum and facilitate transcutaneous delivery o
98 by histological analysis showing an impaired stratum corneum and higher cellular infiltration after p
99 e delivery of encapsulated molecules via the stratum corneum and mammary ducts in a formulation-depen
100 eposited significantly more dye via both the stratum corneum and mammary ducts, while the 80% and 70%
101 lved in the physical barrier function of the stratum corneum and provide innate cutaneous host defens
102 to the cornified envelope) is present in the stratum corneum and retains the ability to form covalent
103 lid microneedles, providing microporation of stratum corneum and therefore enhancement of topical dru
104 elivery system that can permeate through the stratum corneum and viable epidermis and efficiently dep
105 within the polymer matrix, breach the skin's stratum corneum barrier and dissolve upon contact with s
106 on due to their ability to bypass the skin's stratum corneum barrier in a minimally-invasive fashion
108 We show that on breakdown of the epidermal stratum corneum barrier, type 2 and type 17 inflammatory
112 This concept is probed using excised human stratum corneum exposed to aqueous solutions of radiolab
114 f keratinocyte SerpinB2 is protection of the stratum corneum from proteolysis via inhibition of uroki
115 permeability barrier homeostasis and reduced stratum corneum hydration, we hypothesized here that epi
116 th ionic and uncharged, partition into human stratum corneum immersed in aqueous solutions to an exte
117 pidermal water loss, increased overt loss of stratum corneum in inflammatory lesions, and impaired st
120 anisotropic brick-and-mortar geometry of the stratum corneum is obtained using the commercial finite
121 trastructural analyses demonstrated abnormal stratum corneum lipid architecture in AD and IV HEEs, in
123 ed changes in skin properties and CCBAs from stratum corneum of healthy human subjects, providing a m
124 Accordingly, the lipid composition of the stratum corneum of Irf6(-/-) skin was abnormal, culminat
125 n, higher protein-to-lipid ratios within the stratum corneum of RHS indicated reduced lipid amounts a
126 strated notable topographical changes in the stratum corneum of skin permeated with CYnLIP that were
128 The impact of the complex structure of the stratum corneum on transdermal penetration is not yet fu
129 evealed interactions between the gel and the stratum corneum or, more specifically, its protein and l
130 ed ductal penetration, but minimally altered stratum corneum penetration as compared to the control s
132 strated downregulation of tight junction and stratum corneum proteins in the skin of patients with se
133 cluding downregulation of tight junction and stratum corneum proteins, even in the absence of clinica
134 orneum in inflammatory lesions, and impaired stratum corneum thickening after phorbol ester treatment
135 markers (filaggrin and loricrin), increased stratum corneum thickness, and significantly reduced T-c
136 inished cholesterol sulfate signal along the stratum corneum toward the migrating epithelial tongue.
138 ecreased intercellular lipid lamellae in the stratum corneum, and aberrant keratinocyte differentiati
139 assessed in culture media and extracts from stratum corneum, epidermis and dermis after 24h, and the
140 ix in the outer layer of mammalian skin, the stratum corneum, has been previously investigated by mul
141 ng the integrity and barrier function of the stratum corneum, particularly during times of skin infla
142 e outermost skin barrier (referred to as the stratum corneum, SC) and subsequent catalytic generation
143 sed to effectively deliver siRNA through the stratum corneum, the major challenge is that this approa
144 ifferentiation and the formation of a mature stratum corneum, which is essential for the skin to prev
145 paired skin barrier function and a defective stratum corneum, with SerpinB2(-/-) mice showing increas
156 ermal changes of the surrounding tissue, the stratum corneum; and information storage is possible in
157 r the baseline antibiotic prescription rate, stratum (county), and potentially confounding patient an
160 tely saline stratum (0-3 m), an intermediate stratum exhibiting a steep halocline (3-3.5 m), and a lo
161 r 100 child-years for LSD versus MSD, by age stratum, for rotavirus was 22.3 versus 5.5 (0-11 months)
163 ts versus 23.06% in NACC; in the 65-69-y age stratum, from 9.42% to 10.39% versus 34.62%; and in the
164 layers, including the stratum corneum (SC), stratum granulosum (SG), stratum basale (SB), and dermis
167 l as stronger staining of cathepsin B in the stratum granulosum of affected individuals than in that
169 minal nucleus (PBG), and interneurons in the stratum griseum superficiale (SGS) that do not project o
174 men, with optimal-normal BP as the reference stratum, hazard ratios for CVD and CHD mortality risk fo
175 d megafauna at four sites within a 900 km(2) stratum in the UK-1 contract area, and at a site ~250 km
176 (CAC) in reclassifying patients from a risk stratum in which statins are recommended to one in which
177 incidence was as follows: in the 60-64-y age stratum, it ranged from 0% to 5.88% in the three populat
178 quitin and mitochondria accumulations in the stratum lacunosum moleculare (SLM) layer, without loss o
179 stimulation of temperoammonic (TA) inputs to stratum lacunosum moleculare of hippocampal area CA1 het
180 adiatum receive both signals, while those in stratum lacunosum-moleculare exclusively receive a gluta
181 ifically targeted to dendritic spines in the stratum lacunosum-moleculare, which form synapses with p
183 diation bacteria, and SR1 in the hypersaline stratum (likely involved in the anaerobic steps of carbo
185 voked by MF stimulation in interneurons from stratum lucidum and stratum radiatum, but not in interne
186 of stratum radiatum interneurons, whereas in stratum lucidum interneurons only GABAergic responses we
187 , the simultaneous MF GABAergic responses of stratum lucidum interneurons, but not of stratum radiatu
188 lutamatergic LTD, which is known to exist on stratum lucidum interneurons, coexists in the same pathw
190 shown that the interneurons of the hilus and stratum lucidum receive this dual monosynaptic input on
191 item EuroQOL scale scores in the noninvasive stratum (mean change of 0.12 for FFRCT vs. 0.07 for usua
192 are; p < 0.0001); in the planned noninvasive stratum, mean costs did not differ when using an FFRCT c
199 ework to estimate summary statistics in each stratum of a binary exposure and in the marginal model u
200 -shaped, and the trends were also similar by stratum of baseline age groups (all p for interaction <
205 building complex architectures in which each stratum of multilayered or stacked films may differ in c
206 e observed between incident hypertension and stratum of noise exposure at frequencies of 250 Hz, 1 kH
208 ess Nr4a2 and occupy a corticoid superficial stratum of the mesopallium, which is clearly comparable
210 wo countries were enrolled into the low-risk stratum of this trial, of whom 49 received c hemotherapy
213 ng the local False Discovery Rate (lFDR) per stratum, or partition, yields the most predictions acros
215 matostatin-expressing cells predominantly in stratum oriens and parvalbumin-expressing cells mostly i
216 transmission to hippocampal interneurons in stratum oriens does not require NMDA receptors and the i
217 ular-spiking interneurons in the hippocampal stratum oriens exhibit a form of long-term potentiation
218 strong high-frequency priming stimulation in stratum oriens inhibits subsequent LTP in the stratum ra
219 on CA1 neurons in the stratum pyramidale and stratum oriens layers of KO hippocampus may contribute t
221 iring patterns, are primarily located in the stratum oriens or pyramidale, have sparsely spiny dendri
222 Conversely, the exact same 5 ms pairing in stratum oriens potentiated both pathways, as did AP-burs
223 nd adenosine receptors counteracted unpaired stratum oriens potentiation following pairing in stratum
224 long-term potentiation (LTP) in hippocampal stratum oriens-alveus (O/A) interneurons requires co-act
227 stribution of the alpha5-GABA(A)R in the CA1 stratum oriens/alveus (O/A) using a combination of immun
228 ) and somatostatin (SOM) interneurons in CA1 stratum oriens/alveus fire during hippocampal theta and
231 ischarged from an emergency room), admission stratum (patients who were admitted to a hospital ward),
233 hway and assigned to the emergency room (ER) stratum (patients who were discharged from an emergency
234 s of the thalamus and anterior hypothalamus, stratum periventriculare of the optic tectum, dorsal teg
236 ositive synaptic sites on CA1 neurons in the stratum pyramidale and stratum oriens layers of KO hippo
237 ty from up to 150 neurons in the hippocampal stratum pyramidale at approximately 1-mm depth within an
242 of stratum lucidum interneurons, but not of stratum radiatum interneurons, displayed a Hebbian form
243 on potentiated MF glutamatergic responses of stratum radiatum interneurons, whereas in stratum lucidu
244 tex (ERC) and CA1 apical neuropil layer [CA1-stratum radiatum lacunosum moleculare (SRLM)] thickness,
245 tratum oriens inhibits subsequent LTP in the stratum radiatum of hippocampal area CA1, potentially by
246 ion in clustered gephyrin is detected in CA1 stratum radiatum of rTMS-treated anaesthetized mice.
247 itatory synapses on pyramidal neurons in the stratum radiatum rarely occurs in hippocampal area CA2.
248 Many interneurons in stratum lucidum and stratum radiatum receive both signals, while those in st
249 ed with preceding presynaptic stimulation in stratum radiatum specifically led to LTP of the paired p
250 sity on CA3 pyramidal cell apical dendrites (stratum radiatum) and an increase in the number of thorn
251 throughout neuronal cell bodies, dendrites (stratum radiatum), and axons (fimbria), but not astrocyt
252 anization, especially in the hippocampal CA1 stratum radiatum, and also diminishes GABA-mediated syna
253 ion in interneurons from stratum lucidum and stratum radiatum, but not in interneurons from stratum l
254 form of GABAergic LTP, while interneurons of stratum radiatum, despite receiving this dual signaling,
260 cation system outperforms the standard three-stratum risk stratification system in predicting the ris
263 , but the predictive capacity of the PERCH 5-stratum score derived from the coefficients was moderate
264 t least two evolutionary strata: a small old stratum shared with M. huetii, and a more recent larger
266 = rest of hospital births) and comparing the stratum specific estimates of every term with their resp
267 ower to detect associated SNPs by estimating stratum-specific false discovery rate (FDR), where strat
270 /=1.5 SD below age, sex, and education-based stratum-specific means on 2 or 3 CERAD assessments or, s
271 dpoint was the proportion of patients with a stratum-specific objective response (partial response or
272 in condensation and margination in the upper stratum spinosum in lesional skin, suggesting impaired i
274 ediate, or high risk using the current three-stratum stratification system endorsed by the National I
275 rement of all current methods that determine stratum structure based on the comparison of gametologou
277 (P for difference = 0.015) in the >/=55-year stratum than in the <55-year stratum, a finding that cou
278 red with M. huetii, and a more recent larger stratum that is probably unique to M. annua and that sto
282 randomly assigned 1:1 in blocks of four per stratum to receive pembrolizumab 200 mg every 3 weeks fo
283 " of mortality was defined a priori for each stratum, to guide the interpretation of interim and fina
284 ; the number of preceding events (predictor, stratum variable); and the within-subject correlation (i
285 the 116 participants in the other secondary stratum was 1.03 (95% CI, 0-2.11; P = .53) and for the e
289 opulation of heterotrophs in the hypersaline stratum (water activities down to 0.762) and a persisten
293 for AMI among total cholesterol (TC) 200-239 stratum were 5.3 (4.89, 5.71) for HCV-positive versus 4.
295 women (20-40 y, n = 38, middle socioeconomic stratum) were recruited in the first trimester of pregna
296 0.0001), whereas in the noninvasive testing stratum, when the cost weight of FFRCT was set to one-ha
297 re explained by body size, hunting modes and stratum, while niche size was influenced by hunting mode
298 andomly assigned (1:1) in blocks of four per stratum with an interactive voice-response and integrate
299 ndomly assigned (1:1:1) in blocks of six per stratum with an interactive voice-response system to rec