ライフサイエンスコーパス: stress to

1 When applying mechanical stress to a bulk metallic glass it responds with elastic

2 ssure approximately parallels the overburden stress to a depth of 17,640 ft (5,377 m) subsea and ther

3 ites not only promotes the interfacial shear stress to a high level and thus results in significantly

4 demonstrate that a 'soft' robot causes less stress to a jellyfish while handling compared to a tradi

5 ved in cross-linked networks by distributing stress to a small fraction of highly strained connected

6 shear-dominant regime requires lower applied stresses to achieve higher cell strains.

7 o significantly blunted the ability of acute stress to activate c-Fos expression within the anterior

8 f mRNA translation occurs pervasively during stress to activate gene expression programs; however, th

9 rats, reduces or blocks the ability of acute stress to activate hindbrain neurons that are immunoreac

10 t couple detection of pathogens and cellular stress to activation of Caspase-1, and consequent IL-1be

11 y that translates laminar flow-induced shear stress to activation of lymphatic sprouting.

12 tivation, thus linking endoplasmic reticulum stress to activation of the NLRP3 inflammasome.

13 nked quantitative and qualitative aspects of stress to adolescent and adult outcomes, a number of que

14 treatments with exogenous ABA or dehydration stress to advance our understanding of the features requ

15 d plPFC and the translation of environmental stress to affective pathology.

16 ly used by the host cell to combat genotoxic stress, to aid its own replication.

17 l that cells detect and respond to oxidative stress to allow adaptation and repair damage, the underl

18 x by MMP14, thereby releasing the mechanical stress to allow for its healthy expansion.

19 es formed, thereby providing sufficient back stress to allow ice shelf thickening.

20 en appears to act in synergy with epithelial stress to allow intraepithelial cytotoxic T cells to kil

21 n factor that undergoes self-cleavage during stress to allow the expression of DNA repair functions a

22 of B-Raf reduces T cell resistance to shear stress to alpha4beta1 integrin ligands vascular cell adh

23 udy that focused on the ability of oxidative stress to alter cysteinyl leukotriene generation.

24 senses metabolic changes during nutritional stress to alter gene expression programs is less known.

25 nt protein deacetylase, senses environmental stress to alter intestinal integrity.

26 respectively, are regulated during oxidative stress to alter O-GlcNAcylation are not fully characteri

27 The biological underpinnings linking stress to Alzheimer's disease (AD) risk are poorly under

28 Although numerous studies link stress to an increase in the incidence of reactivation f

29 highlights the contribution of environmental stress to anhedonia (loss of pleasure and/or motivation)

30 This pathway spans from initial stress to antibiotic target and demonstrates that TA beh

31 cleavage of SIRT1, a mechanism linking cell stress to apoptosis and SIPS.

32 ent (KO) mice endowed with chronic oxidative stress to assess the influence of aging-associated redox

33 of the mouse spermatozoon against oxidative stress to assure fertilizing competence.

34 at such unfavorable topography may present a stress to attached cells.

35 core with ceftriaxone the capacity of acute stress to augment the acquisition of cocaine self-admini

36 agy is turned off during prolonged oxidative stress, to avoid overeating and destruction of essential

37 By applying environmental stress to bacteria in a microfluidic platform, we can co

38 Thus, our data define proteostatic ER stress to be a specific consequence of inadequate BiP av

39 In conclusion, we found stress to be associated with increased fasting glucose l

40 ication of lipid peroxide-mediated oxidative stress to be different in survivors and non-survivors.

41 ecent clinical studies demonstrate oxidative stress to be present early in ADPKD.

42 mechanisms of drug action and resistance was stressed to be essential for the design of new agents an

43 method, which allows for controlled types of stresses to be applied at the interfaces.

44 n a silica cladding allows large anisotropic stresses to be set into the crystalline material so that

45 cks, as well as the causes of these physical stresses, to be identified.

46 oss the range of dehydration from mild water stress to beyond turgor loss point.

47 of a kappa antagonist administered following stress to block forced swim stress-induced reinstatement

48 en both milk samples were subjected to shear stress to break the curd system at constant shear rate,

49 Paclitaxel-induced ER stress to breast cancer (BCa) cells promotes RNF5 associ

50 Stress to calcium metabolism was defined as elevated int

51 activation of JNK or IKK, is pivotal for ER stress to cause hepatic insulin resistance.

52 as miR-451 depletion synergizes with oxidant stress to cause profound anemia in zebrafish embryos.

53 gase that connects metabolic and heavy metal stress to cell cycle regulation.

54 Using a novel apparatus to apply mechanical stress to cell-cell junctions, we showed that knockdown

55 ture measurements have the advantage of less stress to cells.

56 ve suggested one potential mechanism linking stress to cellular aging, disease and mortality in human

57 Brain circuits are plastic and remodeled by stress to change the balance between anxiety, mood contr

58 Application of high fluid shear stress to chondrocytes recapitulates the earmarks of OA,

59 one kinase Tda1 to link external low glucose stress to chromatin regulation.

60 olecular chaperones that respond to cellular stresses to combat protein aggregation.

61 f PTSD and suggests the potential of ongoing stress to compound initial stress reactions and lead to

62 cells actively exert physical forces (solid stress) to compress tumour blood vessels, thus reducing

63 his report we have examined the use of shear stress to condition synthesized material prior to applic

64 groups were exposed to chronic unpredictable stress to confirm findings from the FST.

65 e renin angiotensin system and macrophage ER stress to contribute to the development of hypertension

66 that functions under conditions of metabolic stress to control systemic energy homeostasis and the ov

67 ther high or low stress, caused the cellular stress to converge to a common level.

68 een insufficient study of mechanisms linking stress to CVD or of methods to attenuate stress' patholo

69 cultured endothelial cells exposed to shear stress to decrease CSE expression and treated with solve

70 static conditions or exposed to fluid shear stress to decrease CSE expression; and (3) cultured endo

71 biofilms can generate sufficient mechanical stress to deform and even disrupt soft epithelial cell m

72 s of anxiety-like behavior, and to restraint stress to determine stress responsiveness.

73 ced swim stress that adds to the interaction stress to determine the global contractility or extensib

74 ged the amygdala, a brain region involved in stress, to determine whether its resting metabolic activ

75 rentiation in Streptomyces, connecting ionic stress to development.

76 Coupling of endoplasmic reticulum (ER) stress to dimerisation-dependent activation of the UPR t

77 was activated by extracellular hyperosmotic stress to directly phosphorylate c-Jun in the serine 63

78 dy utilized the sensitivity of semen to heat stress to discriminate the heat-tolerance ability of pig

79 ortex is moderately diminished during normal stress to disinhibit these loci.

80 thway from adverse childhood experiences and stress to disruption of the development of neural system

81 Oxidative stress to E. coli occurred via formation of hydroxyl rad

82 -126 and by the application of laminar shear stress to ECs.

83 ver, the potential for oxidative/nitrosative stress to elicit an autoimmune response or to contribute

84 ibly manipulated between 0-8 GPa compressive stresses to enable systematic and reversible changes in

85 xert harmful effects, ranging from oxidative stress to endothelial dysfunction, nitric oxide disarray

86 f the plant defense system against oxidative stress to engineer tolerant plants in the climate change

87 ptic potentiation after attack and traumatic stress to enhance aggression.

88 K directly activates mTORC2 during energetic stress to enhance cell survival.

89 is a strategy employed by plants exposed to stress to enhance resistance against future stress episo

90 utrients and growth factors and inhibited by stress to ensure that cells grow only during favorable c

91 ost-transcriptional regulation under uranium stress to enter a cellular dormant state, thereby provid

92 protein response and thus directly links ER stress to ER-phagy.

93 ) concentration (c(i) ) modified by salinity stress to estimate g(m) was proposed.

94 the DA system may underlie the propensity of stress to exacerbate psychotic disorders or predispose a

95 revisiae cells treated with and without salt stress to explore population variation and identify cell

96 We used zebrafish with FLD and hepatic ER stress to explore the relationship between Atf6 and stea

97 the symmetry between tensile and compressive stresses to facilitate mesoscale network contraction of

98 were prepared, thermomechanically cycled and stressed to failure under tension.

99 fic regions of the VTA both during and after stress to fuel later escalated cocaine taking and seekin

100 The mechanisms linking ER stress to HACS activation are not known.

101 t the gamble to induce systemic self-harming stress to harm pathogens may not pay off in the end.

102 ses are set into motion that link early life stress to health disorders in the later years?

103 Research relating stress to health has progressed from anecdotal evidence

104 le reviews recent studies connecting chronic stress to health outcomes in parents of children with in

105 had similar aortic dimensions and wall shear stress to healthy volunteers and younger patients with B

106 d, culture, and apply calibrated fluid shear stress to hEMVs (takes 1-7 d); and how to assess vascula

107 response to paraquat (PQ)-induced oxidative stress to identify pre-symptomatic signatures of impendi

108 crease in depression with physician training stress to identify predictors of depression.

109 n Ganges and Prayon plants in response to Cd stress to identify transporter genes that were more high

110 er the NLRP3 inflammasome connects metabolic stress to IL-1beta-mediated inflammation and provides a

111 Application of fluid shear stress to immortalized osteoblasts from Pkd1(null/null)

112 ts define a pathway linking vascular oxidant stress to immune activation and aortic stiffening and pr

113 uture decades, we can expect deficit-related stress to increase and consequently Douglas fir growth t

114 s to acute stress, and blunts the ability of stress to increase anterior pituitary release of adrenoc

115 Importantly, nitrogen interacted with heat stress to increase bleaching severity up to twofold when

116 r 1 (HSF1) mediates the cellular response to stress to increase the production of heat shock protein

117 rated rats were subjected to water avoidance stress (to induce visceral hypersensitivity), then given

118 st-menopausal women underwent a passive heat stress to induce hot flushes at baseline and follow-up.

119 es suggest that FAAH is required for chronic stress to induce hyperactivity and structural remodeling

120 FC derived from tumour cells is required for stress to induce lymphatic remodelling and that this dep

121 lin C leaves the nucleus following cytotoxic stress to induce mitochondrial fragmentation and apoptos

122 ground, Rps27l disruption triggers ribosomal stress to induce p53 and apoptosis, whereas under Trp53(

123 in enterocytes integrates multiple different stresses to induce regeneration.

124 which is activated upon heat shock and other stresses to induce the expression of molecular chaperone

125 ertilization interacted with competition and stress to influence biomass and changes in height, respe

126 nonsynonymous OXTR SNP interacted with early stress to influence relevant behavioral stress reactivit

127 Critically, rs12938031 interacted with stress to influence reward learning: both behaviorally a

128 rnight fast by blocking the ability of acute stress to inhibit food intake, and by attenuating stress

129 ctivation, to clarify the relationship of ER stress to intra-acinar trypsinogen activation in pancrea

130 degrees C following 60 min 42 degrees C heat stress to investigate specifically the early events in t

131 tant exhibiting constitutive plastid osmotic stress to investigate the molecular and genetic pathways

132 (Populus x canescens) were exposed to water stress to investigate xylem sap sulfate and ABA, stomata

133 etabolic derangement and excessive oxidative stress to ion channel/transporter dysfunction that predi

134 However, the coupling of ER stress to IRE1 oligomerization and activation has remain

135 ex vivo perfusion of arterial laminar shear stress to isolated veins further confirmed the correlati

136 involvement in adaptive threat-biases under stress, to its chronic engagement in anxiety disorders i

137 ory activation of autophagy during prolonged stress to keep the levels of this process under a safe a

138 autophagy is the missing link from oxidative stress to LHON pathogenesis.

139 suggest a novel mechanism linking oxidative stress to ligand-independent cleavage of p75(NTR), resul

140 but the molecular mechanisms that link this stress to lignification remain largely unknown.

141 e heart under conditions of in vivo cellular stress to likely modulate vascular responses to neurohor

142 e lithium distribution by applying different stresses to lithium alloy materials.

143 is a technique for applying local mechanical stresses to living cells.

144 escence microscopy, we applied defined shear stress to low- or high-affinity LFA-1 and imaged the spa

145 ts performed better than the wild type under stress to maintain a favorable instantaneous water use e

146 be protected from genotoxic and proteotoxic stress to maintain a healthy pool throughout life(1-3).

147 litating DNA replication under conditions of stress to maintain genomic integrity.

148 nd survival in vivo by resolving replicative stress to maintain genomic stability.

149 s the distribution and magnitude of traction stresses to maintain a constant strain energy.

150 ases degrading collagen are activated during stress to make proline available, and proline oxidase, t

151 eptibility of mutants sensitive to oxidative stress to MalE-LacZ lethality indicates that ROS contrib

152 To test this, we used abiotic stresses to manipulate the availability of reducing powe

153 her temperatures, bringing increased drought stress to many ecosystems.

154 clinical evidence linking specific types of stress to maternal inflammatory load during pregnancy.

155 d be focused during periods of environmental stress to maximize removal efficiency.

156 with the radiotracer injections at rest and stress to measure blood flow.

157 endotoxin (LPS) model of evoked inflammatory stress to measure plasma IL-1 receptor antagonist (IL1RA

158 G was computed as the ratio of imposed shear stress to measured shear strain.

159 Whether Nox4 acts as a sensor of energy stress to mediate activation of autophagy is unknown.

160 acid (ABA) is induced in response to abiotic stress to mediate plant acclimation to environmental cha

161 the monolayer edge better align velocity and stress to migrate faster toward the open space.

162 The mechanism that couples shear stress to migration has not been fully elucidated.

163 al stability of nanobeams under high tensile stress to minimize thermal buckling effects, therefore k

164 sessile organisms can adapt to environmental stress to mitigate its adverse effects.

165 re exists a window of opportunity even after stress to mitigate its impact with a second surge of exo

166 It is proposed that stress to mitochondria of individual RGCs is a major tri

167 ngs suggest that CaMKII could couple disease stress to mitochondrial injury.

168 ession networks before and after exposure to stress to model the effect of stress on mutational robus

169 Ball-milling utilizes mechanical stress to modify properties of carbon nanotubes (CNTs) i

170 Similarly, the ability of acute stress to modulate amygdala FAAH and AEA in both rats an

171 N is the critical link that allows oxidative stress to modulate nSMase2 phosphorylation and function.

172 esponse transducer IRE1alpha under genotoxic stress to modulate repair programs and sustain cell surv

173 in reproductive tissues in response to heat stress to modulate resource allocation dynamics.

174 inuously reorganize, adapting in response to stress to modulate the calcium signaling apparatus.

175 An analytic model for the strength, or stress to move a dislocation, owing to the random field

176 l the channel banks create just enough shear stress to move the median-sized gravel particles on the

177 importance of cell contractility and tissue stress to multicellular vertex formation and resolution,

178 the ratio of horizontal compressive tectonic stresses to near-surface gravitational stresses is relat

179 The cumulative science linking stress to negative health outcomes is vast.

180 ated molecular patterns (SAMPs)" coupling ER stress to NF-kappaB-dependent inflammation.

181 dent of frequency offset, and (d) reduce the stress to NMR hardware (e.g., cryoprobes).

182 ative effects on water retention from carbon stressed to nonstressed hosts.

183 ther oncogenes, BRAF(V600E) causes oncogenic stress to normal cells, leading to growth arrest (senesc

184 f control on behavior, led even controllable stress to now produce functional desensitization of DRN

185 es, ultimately describing a vicious cycle of stress to obesity to stigma to stress.

186 s suggested defense reactions towards biotic stress to occur which did not lead to adequate responses

187 is definition to include the transmission of stress to offspring via early postnatal care, as animal

188 strategy based on tolerating the effects of stress to one of escaping the stress via reproduction.

189 in its toxicity profile from mainly membrane stress to one that exhibited not only sustained membrane

190 ing to multiple insults, including oxidative stress to orchestrate apoptotic and autophagic cell deat

191 at activate innate immunity, thus connecting stress to organ-specific inflammation.

192 riments use thermal, chemical, or mechanical stress to perturb the folding equilibrium for examining

193 Intriguingly, while application of oxidative stress to phase I and II iron-limited cells similarly ox

194 oles in the signaling steps that link biotic stresses to plant defense responses and growth changes.

195 r rapidly fluctuating light conditions cause stress to plants.

196 uopathies, but the consequences of genotoxic stress to postmitotic neurons are poorly understood.

197 hurricane symptomatology and interacted with stress to predict externalizing symptoms.

198 ly exacerbating and buffering the effects of stress, to predict anthropometry during childhood, and b

199 Research links psychosocial stress to premature telomere shortening and accelerated

200 chondria must buffer the risk of proteotoxic stress to preserve bioenergetics, but the role of these

201 endothelial cells during elevated oxidative stress to preserve functional viability of the intima.

202 d in response to DNA lesions and replication stress to preserve genome integrity.

203 al for targeting IL-33, ILC2s, and oxidative stress to prevent and/or treat asthma development relate

204 kinase Rad53 is activated during replication stress to prevent fork collapse, an essential but poorly

205 quickly adjusted in response to replication stress to prevent genome instability.

206 Multiple pathways counteract DNA replication stress to prevent genomic instability and tumorigenesis.

207 egrity by clearance of individual HSCs after stress to prevent propagation of damaged stem cells.

208 uitinases associate more with Rsp5 upon heat-stress to prevent the assembly of K63-linked ubiquitin o

209 amaged areas from the increase in mechanical stress to prevent/mitigate failure.

210 deacetylase (HDAC) inhibition, caused adult stress to produce changes similar to those induced by ad

211 e, seasonal and annual streamflow, and water stress) to projections of future climate.

212 t deoxyuridine could abrogate ROS-induced ER stress to promote cancer cell survival.

213 Our study demonstrated that HFD induces ER stress to promote chondrocyte death and subchondral bone

214 ast-Thbs4, emerged after induction of tissue stress to promote fibrosis in the absence of smooth musc

215 transmits structural changes in response to stress to promote holdase activity is unknown.

216 a/delta can repress this oncogene-induced ER stress to promote senescence in accordance with its role

217 tifs are sufficient to bear normal and shear stress to promote significant and tunable adhesive prope

218 the translational landscape during cellular stress to promote survival.

219 cellular anabolic signals and antagonizes ER stress to promote T cell metabolic fitness.

220 pression is up-regulated in response to cell stress to protect against pathological cell death in mul

221 at shock proteins, during times of oxidative stress to protect against proteotoxicity.

222 ance vessels develop resilience to oxidative stress to protect functional integrity and tested this h

223 nd respond dynamically to pH and temperature stresses to protect client proteins from aggregation.

224 2/RelB and IKK2-p65, is activated by various stresses to protect or damage the liver, in context-spec

225 re was no indication of diminished oxidative stress to proteins or lipids, and no evidence for anti-i

226 on the GR, monitoring the level of cellular stress to redirect glucocorticoid-regulated signaling th

227 Here, we show that cells can sense nitrogen stress to reduce target of rapamycin complex-1 (TORC1) a

228 aR is phosphorylated in response to membrane stress to regulate downstream target operons.

229 ow NOD1 and NOD2 sense microbes and cellular stress to regulate host responses that can affect diseas

230 switch, which is activated during oxidative stress to regulate the balance between cell survival by

231 ts highlight the role of FoxO in limiting ER stress to regulate Tsc1 mutant overgrowth.

232 ient status, growth factor availability, and stress, to regulate cellular and organismal growth.

233 red on the intricacies of how cells use such stresses to regulate their internal mechanical integrity

234 regulated proteolysis of cTnI during cardiac stress to remove the unique cardiac N-terminal extension

235 undant molecular responses to neutralize the stress, to repair the damage and to eventually grow insi

236 and can be activated in response to diverse stresses to replenish all blood cell types.

237 x transrepressor directly transduces osmotic stress to repress stomatal development to improve plant

238 cardial perfusion reserve (MPR, the ratio of stress to rest MBF).

239 obtained from our previous rest study by the stress-to-rest TIAC ratio obtained from the rest-stress

240 a means of reducing the effect of oxidative stress to RPE cells in age-related macular degeneration.

241 olded protein response/endoplasmic reticulum stress to secretory optimization, coordinated with cell

242 ted within blood vessels by high-fluid shear stresses to selectively target drugs to sites of vascula

243 hile hydrogen peroxide distributes oxidative stress to sensitize the network to mitochondrial critica

244 suggesting the role of endocannabinoids and stress to sexual differentiation of the brain and cerebe

245 gated to a conjugated state under mechanical stress to significantly change their properties, we deve

246 ne inactivation of Rps27l triggers ribosomal stress to stabilize Mdm2, which degrades Mdm4 to reduce

247 ndividuals with a history of repeated social stress to substance abuse behaviors.

248 CREB dysfunction, and promote survival under stress to support the hypothesis that lower molecular we

249 advances have allowed the study of oxidative stress to tackle fundamental questions and have provided

250 s the first study (to our knowledge) to link stress to telomere length in a non-WEIRD population, our

251 for a mechanism linking cumulative childhood stress to telomere maintenance, observed already at a yo

252 ecological momentary assessment of patients' stress to test hypotheses about clonidine's behavioral m

253 We examined the effects of a modest heat stress to test the hypothesis that SSNA responses could

254 cation of an external vibrational mechanical stress to that tissue.

255 echanism to eliminate cells during metabolic stress to the advantage of a multicellular organism.

256 In the case of local salt stress to the Arabidopsis thaliana root, Ca(2+) wave pro

257 Initial damage or stress to the coral via other competitive mechanisms is

258 meability can be modulated by applying shear stress to the droplet interfaces, inducing flow parallel

259 tivity of bortezomib by promoting additional stress to the endoplasmic reticulum of MM cells.

260 n inhibitor of tumor progression by altering stress to the endoplasmic reticulum, down-regulating per

261 des insight into a new paradigm linking cell stress to the immune response, and serves as a template

262 n appear to link energy balance and cellular stress to the intracellular signal transduction pathways

263 caspase-2-dependent mechanism that relays ER stress to the mitochondria to promote inflammation, inte

264 redox regulatory switch that links oxidative stress to the modulation of TDP-43 and its downstream ta

265 sive folding" design to apply conformational stress to the monomeric state.

266 ted States recover from acid deposition, the stress to the most susceptible populations of native col

267 ministering a peptide that reduces oxidative stress to the mouse model.

268 y TRPM2 as a key factor that links oxidative stress to the NLRP3 inflammasome activation.

269 the nucleus by applying a transient tensile stress to the nuclear membrane.

270 e not only for contribution of mitochondrial stress to the pathology of ITP, but also clinical potent

271 Functional radiography provides the maximum stress to the pelvic floor, resulting in levator ani rel

272 that link pathogen recognition and cellular stress to the processing of the proinflammatory cytokine

273 owth, and a molecular mechanism linking this stress to the regulation of growth in developing organs,

274 sHSPs) are preferentially translocated under stress to the sarcomeres.

275 oxic, conformal therapy, to deliver acoustic stress to the tumor for immune priming.

276 cell-free virus did not reflect the level of stress to the VZV-infected cell that was seen after inoc

277 that is proportional (at constant interface stress) to the -1/3 power of this rate.

278 ellular status information, such as cellular stress, to the integrity of microtubules in order to ins

279 evant conditions, ranging from environmental stresses to the biotechnological production of small mol

280 et exert minimal mechanical and inflammatory stresses to the vessel wall.

281 gic effects, but the neural circuits linking stress to these responses are not well understood.

282 fficient, defined as the ratio of protrusive stress to tissue-substrate friction, that allows classif

283 ction was observed in the transmission of ER stress to TLR4 KO macrophages, consistent with the fact

284 1P1 responds to S1P as well as laminar shear stress to transduce flow-mediated signaling in endotheli

285 chanism for potentially translating membrane stress to transport regulation.

286 logies to use nanoparticle-induced oxidative stress to treat disease in a site-specific fashion.

287 atin-remodelling factor that is activated by stress to trigger aberrant gene expression and cardiac m

288 ecules that exacerbate LIP-induced oxidative stress to trigger ferroptosis.

289 anched actin networks builds up a sufficient stress to trigger sustained motility.

290 se motors generate sufficient thick-filament stress to trigger the transition to its long-periodicity

291 consecutive MDE it may take lower levels of stress to trigger these neurotoxic pathways, leading to

292 ability of cortisol, released in response to stress, to trigger a cascade of adaptive genomic and non

293 therapeutic potential of blocking Chop or ER stress to unleash T cell-mediated antitumor immunity.

294 r the past 2 decades, the contribution of ER stress to various forms of liver diseases has been exami

295 ins in the endoplasmic reticulum (ER) causes stress to which an unfolded protein response is activate

296 Available data suggest that the cold stress to which laboratory mice are ubiquitously subject

297 epending on the function of the cells or the stress to which they are exposed.

298 epending on the function of the cells or the stress to which they are exposed.

299 l pathway, but rather one guided by uniaxial stress, to which the nanothreads consistently align.

300 Finally, by applying heat stress to whole seedlings, we address the longstanding q