ライフサイエンスコーパス: strong base

1 ditions for C-N coupling reactions (heat and strong base).

2 ions (visible light, ambient temperature, no strong base).

3 ement over existing protocols that require a strong base.

4 , we show that MeOH is produced when using a strong base.

5 but override the Heck pathway by employing a strong base.

6 alkylated at 2-N with methyl propenoate and strong base.

7 e dissolution of the PSi nanocrystallites in strong base.

8 air and moisture, and even resist acids and strong bases.

9 reported to be resistant to deprotonation by strong bases.

10 uted quinuclidines are screened as potential strong bases.

11 ecourse to protecting-group manipulations or strong bases.

12 and effectively making phosphines and amines strong bases.

13 ification conditions; recovery was poor with strong bases (0.2 and 0.5 M KOH) and best with weak base

14 (3 m HCl or 3 m H(2) SO(4) for one week), a strong base (20 m NaOH for one week), and boiling water

15 The reaction does not require strong base/acid or sulfur/selenium reagents and can be

16 n, and the unknown) were best recovered with strong base after 6 hours of saponification at room temp

17 After treatment with KO(t)Bu as a strong base, all but the two least acidic compounds were

18 id functionality with an organically soluble strong base and (ii) heteroconjugation of anions of carb

19 an epoxidase that oxygenates vitamin K to a strong base and a carboxylase that uses the base to carb

20 ential treatment of H-phosphinothioates by a strong base and a primary alkyl iodide constitutes an al

21 m in which an aqueous medium that contains a strong base and a small organic molecule acting as a hyd

22 out during methylation in the presence of a strong base and by liquid extraction of the per-O-methyl

23 is reported that dimsyl anion, formed from a strong base and DMSO (solvent), is responsible for induc

24 e title reaction, which include the use of a strong base and N-mono- or N,N'-disubstituted 3,3-diamin

25 SDVB-based strong acid cation exchangers and strong base and weak base anion exchangers were evaluate

26 hough this protecting group is stable toward strong bases and nucleophiles, long reaction times are r

27 ODN synthesis, deprotection is achieved with strong bases and nucleophiles.

28 mild oxidative conditions without using any strong bases and nucleophiles.

29 he benzylation of alkynes without the use of strong bases and/or organometallics.

30 echanism where MeMgCl acts as a nucleophile, strong base, and Lewis acid possibly explains the format

31 ic chemistry as the drawbacks of traditional strong base- and acid-mediated etherifications have beco

32 After AS18 latex coating, the strong base anion exchange capacity was on the order of

33 imilar or better than commercially available strong base anion exchange resins.

34 aternary ammonium-functionalized HAIX resin (strong base anion exchange, SBA) to a tertiary amine ver

35 articles (CaF2-Eu) with either TEVA resin or strong base anion-exchange resin (Dowex 1 x 8-400(Cl)).

36 Strong bases are avoided in this desaturation approach,

37 f octamethylcyclotetrasiloxane (D(4)) with a strong base as the catalyst.

38 and a benzyl electrophile in the presence of strong bases at high temperatures.

39 m the molecular dynamics simulations, reveal strong base-base interactions in the junction that criti

40 not merely by the need for an exceptionally strong base, but by the inherent instability of the resu

41 sted probase strategy is devised, in which a strong base can be generated in situ from silylamide (pr

42 reaction involving cryogenic temperature and strong base conditions.

43 useful compounds by not requiring the use of strong base, cryogenics, or an anhydrous and inert atmos

44 uterium exchange experiment has shown that a strong base (DABCO) facilitates the deprotonation reacti

45 ing group strategy in which non-nucleophilic strong-base (DBU) labile nucleobase protecting groups an

46 This method avoids the use of strong base, does not necessitate inert or low temperatu

47 ong periods in significant concentrations of strong base (e.g., >/=10 mM NaOH).

48 This electrochemical method does not require strong base, exogenous expensive transition metal cataly

49 atalyst or a stoichiometric activating agent/strong base/external additive.

50 ed SAMs either requires inert atmosphere and strong base for deprotonation of imidazolium precursors

51 rementioned model organisms still provides a strong base for dissecting light responses in such speci

52 the inner wall of capillary, pretreated with strong base for hydrolyzing the ester.

53 ive, or correlational designs that provide a strong base for understanding the validity and reliabili

54 hyl chlorofluoroacetate, when treated with a strong base, forms an alpha-chloro-alpha-fluorocarbanion

55 This model will serve as a strong base from which to develop a systems biology unde

56 eatment of CYP4B1, CYP4F3, and CYP4A5/7 with strong base generated a new, chromatographically distinc

57 In the presence of strong base, however, N-protected indazoles are prone to

58 treatment with tert -butyl hydroperoxide and strong base in acetonitrile to generate a metastable com

59 s to reducible 1,3-cyclohexadienes without a strong base in its oxidized thioquinone methide form.

60 f weak base character, about the same as the strong base ion exchange capacity.

61 ryl fluorides at ambient temperature without strong base is demonstrated.

62 he case of photosynthetic water oxidation, a strong base is postulated to facilitate the deprotonatio

63 B(C6 F5)4], was simply deprotonated with the strong base K(N(SiMe3 )2 ) to give 5.

64 ntrast, addition of a second equivalent of a strong base leads to S-N cleavage and production of an {

65 Whereas standard strong bases (n-BuLi, s-BuLi/TMEDA, n-BuLi/t-BuOK, TMPMg

66 Hence, we used a strong base, NH(3), in positive mode to produce NH(4)(+)

67 innings of health and health inequalities; a strong base of international support from the Diaspora J

68 eloped for the determination of concentrated strong bases ([OH-] = 1-10 M).

69 k, moderate, good/strong, and very good/very strong based on results.

70 s was categorized as "weak", "moderate", or "strong", based on estimate of effect sizes, heterogeneit

71 ry inert and can only be activated by a very strong base or a metal catalyst.

72 d for dry environment, addition of exogenous strong base or restricting synthetic steps.

73 operates under mild conditions without using strong bases or acids.

74 iguous C-C bonds and eliminates the need for strong bases or expensive metal catalysts.

75 The latter could be rearranged with strong base, oxidized, and deprotected to the desired o-

76 posed that a weak base (cysteine) produces a strong base (oxygenated KH(2)) capable of generating the

77 resence of catalytic amounts of the nonionic strong bases P(RNCH(2)CH(2))(3)N (R = Me, i-Pr, i-Bu) in

78 ntaining single-stranded RNA (ssRNA) free of strong base pairing interactions can be created either b

79 A-mRNA interactions identified by CLASH have strong base-pairing potential and are highly enriched fo

80 h binds U1 small nuclear RNP (snRNP) through strong base-pairing with U1 snRNA.

81 enriched in clay and the other, OM, using 29 strong bases (pKa > 8).

82 ooxidation of isopropanol in the presence of strong base (potassium t-butoxide) with an onset potenti

83 um compounds synthesized on treatment with a strong base produce the 1,4-imino tautomer whose UV spec

84 In this approach, the strong base produced will be transient and not be in exc

85 the crystallinity of M(2)CO(3) and engenders strong base reactivity at intermediate temperatures.

86 arnesyl group is not stable to the excess of strong base required for rearrangement of a vinyl phosph

87 esyl lactone was not stable to the excess of strong base required for the rearrangement.

88 droxybutanoate carbonate) in the presence of strong base results in a stepwise unzipping of the polym

89 ve and ferrocyanide positive electrolytes in strong base shows stable cycling performance, with over

90 Strong-base stability of the photolabile linker allowed

91 Strong base stacking at the 3'-RNA terminus can compensa

92 rget protein binds to the aptamer probe, the strong base stacking effect can lead to a favorable and

93 pared with C3'-endo/anti conformers and very strong base stacking in fd DNA; hydrogen-bonding interac

94 e natural DNA context revealed exceptionally strong base stacking propensity for both.

95 ementarity, extensive protein side-chain and strong base-stacking interactions for the guanine moiety

96 xyurea and methyl methanesulfonate, and is a strong base substitution and frameshift mutator.

97 In the presence of strong bases such as NaOt-Bu, KOt-Bu, and NaH, clean for

98 th pK(a) measurements, the requirement for a strong base suggests that the deprotonation of a six-coo

99 tes a free hydroxide ion as an exceptionally strong base that is required to deprotonate the gamma-ca

100 arious functional groups that react with the strong bases that are typically used in Pd-catalyzed C-N

101 These reactions avoid using oxidants or strong bases, thus, tolerating various functional groups

102 nveniently, without the need for an external strong base to generate the NHC by deprotonation of an a

103 rate chemical hydrolysis procedures--using a strong base to recover xanthophylls and a weak base to r

104 vivo, recognizing a special DNA context with strong base-unpairing propensity.

105 ated the formation of enolate anions without strong base use.

106 no lactone, in part, because only 1 equiv of strong base was required.

107 m alcohols, phenols, thiols and alkynes with strong bases, we successfully synthesized a library of n

108 ide complexes, which makes the newly studied strong base-weak acid reaction essentially different fro

109 Typical reaction conditions involve either a strong base, which limits the scope of substrates, or an

110 ffect of pH on the sorption coefficients for strong bases with pK(a) > 7 was small, within 0.3 log un

111 substitution reaction upon treatment with a strong base, yielding either cycloalkylphosphine derivat