ライフサイエンスコーパス: structural difference

1 h can serve as an alternative or additive to structural differences.

2 rated independent of biochemical and spindle structural differences.

3 rthologs is predicted to manifest as notable structural differences.

4 ion of an extra inertial term accounting for structural differences.

5 usually analyzed in 3D for interpretation of structural differences.

6 the larger conformer suggesting considerable structural differences.

7 ed into eight families based on sequence and structural differences.

8 that reported for HlgAB, but with important structural differences.

9 r flap structure-selective nucleases despite structural differences.

10 and mammalian CTDs, which is consistent with structural differences.

11 for SITBs indicated a lack of convergence on structural differences.

12 olymer lengths and linkages and their subtle structural differences.

13 microscopic and physical analyses to reveal structural differences.

14 king it likely that they contribute to these structural differences.

15 uidity in addition to the already determined structural differences.

16 for isomeric carbohydrates with even subtle structural differences.

17 the bovine enzyme, indicating that inherent structural differences affect ligand access in these enz

18 cture can be studied, even revealing gradual structural differences along a peak.

19 re and sulfation pattern of a given GAG, and structural differences among GAGs and among chemokines i

20 le focuses on the pore region, reviewing how structural differences among glutamate receptor subtypes

21 d to specific moieties can identify distinct structural differences among HS sources as well as provi

22 which is astonishingly long, given that the structural differences among the filter conformations ar

23 that observed with cholesterol, although the structural differences among them are subtle.

24 d coils in solution, there exist significant structural differences among them at shorter timescales.

25 entity threshold, performs analysis of their structural differences and clusters them according to th

26 To better understand how the details of structural differences and similarities influence the To

27 investigate the functional impact of the key structural differences and their respective role in the

28 stigate the relationship between age-related structural differences and visual evoked field (VEF) and

29 nsisting of whole-brain activity maps, brain structural differences, and profiles of behavioral abnor

30 equal clustering we study and quantify their structural differences, and using SIS (Susceptible-Infec

31 2D NMR spectroscopic data suggest that structural differences are associated with different cys

32 med by micro-CT of human lung specimens that structural differences are associated with unique S(fSAD

33 Structural differences are clustered in peripheral and s

34 These dramatic structural differences are consistent with the measured

35 nd two isomeric tetrasaccharides with subtle structural differences are distinguished rapidly and acc

36 Remarkably, we find that these structural differences are largely controlled by only tw

37 mouse and Syrian hamster and show that their structural differences are mainly governed by two residu

38 In comparison to the unmodified trimer, structural differences are observed at the interface bet

39 Two main structural differences are observed in that the N-termin

40 remains unclear whether all of the observed structural differences are part of the allosteric mechan

41 cides with a region of the active site where structural differences are seen between tankyrases and o

42 Major structural differences are seen between the full-length

43 otocol offers unique opportunities to detect structural differences arising from various experimental

44 eal pit morphometry to investigate potential structural differences as a function of age and refracti

45 the samples was primarily explained by block structural differences as determined by HPSEC-PAD.

46 nmt3b, or Tet2 did not lead to functional or structural differences at baseline or after toxic injury

47 l three enzymes were solved, revealing major structural differences at the N-terminal domain and dime

48 bria between two sub-states exhibiting small structural differences at the terminal methine bridges A

49 These results suggest a potential structural difference between active and inactive networ

50 ncy with autoimmune aHUS could be due to the structural difference between CFHR1 and the autoantigeni

51 In this study we present an alternative structural difference between cyano- and iodocuprates, w

52 charide composition analysis showed no major structural difference between heparan sulfate from contr

53 y of prothrombin in solution and the drastic structural difference between its alternative conformati

54 gical and biochemical results concerning the structural difference between membrane glycoproteins of

55 Our results indicate that a subtle structural difference between paradox inducers and break

56 This structural difference between the bacterial and host cel

57 Specifically, our study revealed a structural difference between the cell envelopes of L. i

58 One key structural difference between the NOS isoforms is the am

59 g chemical probing analysis, we identified a structural difference between the two 5'UTRs in the high

60 The structural difference between the two hexasaccharides wa

61 monomeric AgamOBP47 revealed that the major structural difference between the two Plus-C proteins lo

62 The minimal primary structural difference between variants was a single amin

63 The most prominent structural differences between Abeta(1-42) oligomers and

64 om the extracellular space to lysosomes, and structural differences between AGs alter the efficiency

65 ay of (14)N and (35)Cl spectra, reveal clear structural differences between all compounds.

66 Despite evolutionary and structural differences between alpha-carboxysomes and be

67 ible evolutionary histories that explain the structural differences between any two genomes can be sa

68 We conclude that despite major structural differences between ATP synthase dimers of ci

69 Based on the structural differences between AVP and AVP-pVIc, we pres

70 The structural differences between bacterial and human prima

71 Subtle structural differences between BCoV and MHV NTDs, primar

72 We show significant structural differences between beta1 and beta3 TM/CT in

73 These results highlight fundamental structural differences between BK and Kv channels in the

74 We propose that the structural differences between bound and unbound forms a

75 Our results about structural differences between DENVs produced in humans

76 nresolvable by other techniques, and reveals structural differences between DHFR and a point mutant (

77 The subtle structural differences between digenite and tetragonal c

78 ence context of 3' splice sites and to small structural differences between drugs.

79 agnetic resonance imaging was used to detect structural differences between groups.

80 esonance spectroscopy was used to reveal the structural differences between H69 with (PsiPsiPsi) and

81 trasaccharide and by taking into account the structural differences between HA, poly-GlcUA, and poly-

82 These data suggest that the structural differences between high- and low-SR synapses

83 Most significant structural differences between HIPK2 and DYRKs included

84 ur results highlight significant dynamic and structural differences between HO2 and HO1 and indicate

85 rm significant and consistent functional and structural differences between hub proteins that are co-

86 In contrast, structural differences between human and shark antibody

87 polymorphisms, but also complex, large-scale structural differences between human individuals and hap

88 on its location within the F structure, and structural differences between its prefusion and postfus

89 is due to changes in AKAP12 localization vs. structural differences between its two variants.

90 lso occurred for Saturn, contributing to the structural differences between Jupiter and Saturn(16-18)

91 isting quantitative model fully explains how structural differences between kinesins alter kinetic ra

92 ces, expression of inflammatory markers, and structural differences between mature hemostatic and gro

93 sequence conservation, there are significant structural differences between microtubules assembled in

94 ond-long atomistic simulations elucidate key structural differences between monomeric ApoE3 and ApoE4

95 ng domains, which allowed us to describe the structural differences between Mre11 bound to exo- and e

96 To explore the hypothesis that structural differences between NaB and VPA account for t

97 The image results from OCT showed structural differences between normal and cancerous tiss

98 The structural differences between oxidized and reduced NQO2

99 To better understand the structural differences between P450s 3A4 and 3A5, the st

100 tion tools are needed to observe more subtle structural differences between particles of different co

101 d within each design without any significant structural differences between phases.

102 It is well established that the structural differences between phospholipids play an imp

103 several new options for visualization of the structural differences between proteins.

104 The minor structural differences between raloxifene and one of its

105 Furthermore, the demonstration that the structural differences between readily degradable and un

106 Despite the minimal structural differences between receptor types, selectivi

107 on is not a general phenomenon of LGICs, and structural differences between receptors may account for

108 There are several intriguing structural differences between resolvase and RuvC, and a

109 on by cryoEM has opened the door to defining structural differences between ribosomes of pathogenic o

110 ke previous hypotheses, we found significant structural differences between SPLUNC1 and BPI.

111 Minor structural differences between substrate- and inhibitor-

112 he canonical maize isoform and with possible structural differences between the apomictic and sexual

113 Structural differences between the C(s)-symmetric single

114 (2+) permeability of NMDA receptors, and the structural differences between the closed and open state

115 This leads to structural differences between the complexes, particular

116 Given that the structural differences between the conductive and inacti

117 These mechanisms involve decreasing structural differences between the effector bound and un

118 n, using Phi-value analysis we show that the structural differences between the hot and cold denature

119 Calculations reveal that the structural differences between the I- and B-forms (the f

120 The polymorphism of HET-s parallels the structural differences between the infectious brain-deri

121 The structural differences between the inward-facing YfkE an

122 face area and surface coverages, rather than structural differences between the iron (oxy)hydroxides.

123 ional structural ensembles, we show that the structural differences between the labeled and unlabeled

124 However, we also noted large structural differences between the orthologues from thes

125 This work reveals long-sought structural differences between the pre-accommodation of

126 tions and interaction modes depending on the structural differences between the RIPs.

127 These structural differences between the RRMs were reinforced

128 ify RNA ligands (aptamers) that could detect structural differences between the secretomes of pancrea

129 This difference is interpreted in terms of structural differences between the synthetic and natural

130 Significant in-lipid structural differences between the two constructs sugges

131 y analyses reveal that there are fundamental structural differences between the two enzymes, and NfnI

132 hetic mechanisms responsible for most of the structural differences between the two metabolites.

133 The structural differences between the two nanosheet assembl

134 connected the binding scaffolds, suggesting structural differences between the various dimer subtype

135 Elucidating the structural differences between their closed and open sta

136 field than DNA, as is predicted based on the structural differences between their helices.

137 transformation of aluminium (oxy)hydroxides, structural differences between them arise from the varia

138 h forms have an alpha + beta fold; the major structural differences between them lie in the beta-shee

139 Galphai1:Ric-8A complex and the magnitude of structural differences between them.

140 tion of the A-tract arrays while maintaining structural differences between them.

141 The structural differences between these complexes of beta(1

142 ansition is surprising in light of the large structural differences between these polymorphs.

143 algorithm that reconciles and preserves key structural differences between these two networks, which

144 We also demonstrate that structural differences between transcript isoforms of th

145 ivity and resolution for detecting localized structural differences between two or more biological pr

146 Furthermore, our results illuminate structural differences between UL144 and HVEM that expla

147 ate the capsid determinants of this process, structural differences between wild-type (wt) AAV2 and a

148 of the chromosome is not likely to be due to structural differences between X chromosomes of European

149 oscopy to gain atomic level insight into the structural differences between Y145Stop prion protein am

150 Our studies demonstrate structural differences between yeast and mammalian micro

151 Despite this structural difference, both two and three disulfide-bond

152 To help explain how these small structural differences can have such a large effect, we

153 We present evidence that despite structural differences, carbamazepine and glibenclamide

154 We now report structural differences caused by amino acid substitution

155 -thiol complexes with moderate but important structural differences commonly found in the environment

156 ae ACE proteins (AnoACE2 and AnoACE3) reveal structural differences compared to human ACE, suggesting

157 s from mice lacking PRMT8 have no detectable structural differences compared with controls; however,

158 odels for the two species according to their structural difference complemented by numerical simulati

159 es" of the unknown: similar compounds with a structural difference confined to a single region of the

160 uctures confirmed the degree to which subtle structural differences could be determined using this me

161 These structural differences could provide insight into their

162 ck of sequence identity and some fundamental structural differences currently designates them as inde

163 The structural differences detected by subtomogram analysis

164 ples of adults, but less is known when these structural differences emerge in youths.

165 functional analysis are consistent with the structural differences evident in the x-ray atomic struc

166 The structural differences exhibited by 3A4 and 3A5 suggest

167 Extremely small structural differences exhibiting collision cross sectio

168 oward depressed CO rates at loci where large structural differences exist between the two parents.

169 onal levels, it has become clear that subtle structural differences exist between the two sides and t

170 Only minor structural differences exist between the W972A RING doma

171 ystal structures of SK1 suggests that subtle structural differences exist in the foot of the lipid-bi

172 s; however, we observe small but significant structural differences for the 1095 procapsid compared t

173 The structural differences found at both Xyn10C-XBD domains

174 hGALT reveals significant structural differences from bacterial GALT homologues in

175 timely in the human olfactory system, whose structural differences from nonprimate macrosmatic speci

176 ecule inhibitor CX-4945, revealing important structural differences from related protein kinases of t

177 E. coli ZapA was determined, identifying key structural differences from the existing ZapA structure

178 ower of this method by (1) extracting subtle structural differences from visually indistinguishable i

179 This is surprising, given that structural differences generally reflect functional diff

180 ely related molecules distinguished by small structural differences, giving rise to individual molecu

181 s in the solid state by introducing a unique structural difference, i.e., an oxovanadium(IV) in a squ

182 We speculate that the distinctive structural difference in the bound complexes of apoCaM-N

183 There was no significant structural difference in the fungal communities between

184 antibiotics) but not to tedizolid because of structural differences in A-ring C5 substituents between

185 Interestingly, despite structural differences in acyl chain composition between

186 uired resistance are attributable in part to structural differences in binding subsites, receptor sub

187 We aimed to investigate whether there are structural differences in children and adults with ADHD

188 Factors, including structural differences in chromanol head and isoprenoid

189 d to available brain or behavioral measures, structural differences in colonic tissue were strongly r

190 andom graphs as a promising model to capture structural differences in confined physical networks.

191 PCE is associated with structural differences in cortical and limbic regions.

192 their unaffected relatives, show widespread structural differences in corticostriatal and limbic net

193 We provide evidence to suggest that structural differences in DsbB oxidases (LpDsbB1 and LpD

194 generation (SHG) imaging microscopy to probe structural differences in fibrillar models of the ovaria

195 Ligand-binding induced structural differences in HER were determined to be loca

196 nd local shape analyses were used to measure structural differences in hippocampi between genotype gr

197 ty for PS(-) lipids, they induce substantial structural differences in lipid bilayers containing each

198 We also found that despite major structural differences in marsupial and eutherian brains

199 This study investigated structural differences in primary visual cortex between

200 se a pH-sensitive loop of FcRn, and identify structural differences in proximity to these hot spot re

201 taneous Raman spectroscopy to understand the structural differences in sense and antisense microRNA-2

202 Poverty is tied to structural differences in several areas of the brain ass

203 ve quaternary structures differ markedly and structural differences in the active site explain the ob

204 Structural differences in the active site region of GCC

205 from MERS-CoV and other human CoVs revealed structural differences in the alpha1 helix alters how th

206 To compare structural differences in the anterior chamber angle (AC

207 closer to this important goal by identifying structural differences in the beta(1)-adrenoceptor in co

208 f their daily experiences and that there are structural differences in the brains of these subjects c

209 This analysis reveals how subtle structural differences in the cage framework affect bind

210 effective anti-infective agents based on the structural differences in the catalytic clefts of ARSs f

211 Structural differences in the chromophore of the red-shi

212 n crystallized in lipidic cubic phase (LCP), structural differences in the Cmpd-1-bound A2AR-BRIL pre

213 ere consistent with known nucleotide-induced structural differences in the Fe protein and indicated t

214 We examined the hypothesis that structural differences in the gut microbiota explain a p

215 tantially higher for the H1 subtype owing to structural differences in the HA stem.

216 y) but differing in their membrane mobility (structural differences in the lipophilic tail).

217 e TcpB TIR domain, which reveals significant structural differences in the loop regions compared with

218 arainfluenza virus 5 (PIV5) F, with the main structural differences in the membrane distal apical loo

219 These structural differences in the Ndc80 complex between diff

220 es in the amygdala bilaterally (but not with structural differences in the Nucleus Accumbens).

221 in translation/accumulation and reverse the structural differences in the Pr loop were found in the

222 genetic variation in DLG4 is associated with structural differences in the preterm infant brain.

223 We propose that structural differences in the subdomains of the Ag43 cla

224 and the diphosphate-specific OprO pores show structural differences in their binding sites situated i

225 rse enzymatic reactions, probably related to structural differences in their respective FAH domains;

226 In conclusion, even small structural differences in these beta-sulfonamide Asp ana

227 om Streptomyces roseosporus, but has notable structural differences in three amino acid residues and

228 Pediatric anxiety was associated with structural differences in vmPFC and hippocampus, regions

229 sum, chronic cannabis use is associated with structural differences in white and gray matter, which w

230 Structural differences, in particular in the DNA strand

231 in ASD may reflect myelination and/or other structural differences including differences in axonal d

232 o be localized in plasma membrane, but their structural differences indicate that they might have dif

233 se proximity to bound analytes so that small structural differences induce distinct (19)F NMR shifts

234 crystalline variants enabled us to identify structural differences induced by the single amino acid

235 Structural differences involving extensive water-mediate

236 The structural difference is located within the cytoplasmic

237 The functional significance of these structural differences is underscored by decreased funct

238 otein, Btl19-13, and found that, despite the structural differences, it can be T3-secreted and can nu

239 The structural differences mandate partitioning of sex and a

240 Considering that their structural differences may affect their physical and oxi

241 ty in cells and in mice, suggesting that the structural differences may play important roles in disea

242 biological activities, in spite of discrete structural differences, may reveal the existence of hydr

243 After adjusting for case-mix and hospital structural differences, model intraclass correlation ind

244 We explain how subtle structural differences, mostly depending on the structur

245 ities and add a functional interpretation to structural differences observed between PDs in different

246 The structural differences observed were specific to the CA

247 Nevertheless, significant structural differences occur in loops connecting the bet

248 Ca(2+)-dependent structural differences occur in the fourth EF-hand (EF4)

249 thick filament formation, and highlight the structural differences occurring between the coiled-coil

250 binding sites for discriminating the subtle structural difference of isomers are urgently needed.

251 The structural difference of the Pd ensembles has a signific

252 lated mitochondrial network, whereas neither structural difference of the peroxisome network, nor alt

253 Moreover, it has been determined that the structural differences of immobilized antibodies (fragme

254 We show that structural differences of miR482/2118 family members in

255 ution mass spectrometry was used to describe structural differences of NKR-P1A receptor.

256 Owing in part to structural differences of NRs, adverse effects of EDCs v

257 d algorithm that quantitatively computes the structural differences of the three-dimensional networks

258 The two tri-DPP molecules with only a structural difference on alkyl substitutions, when blend

259 We investigated consequences of structural differences on resting-state functional conne

260 d-free nanobody-receptor interaction reveals structural differences on the cytoplasmic receptor side

261 -coordinate Fe(II) forms, revealing striking structural differences on the heme-proximal side of the

262 rystallographic studies revealed significant structural differences, particularly in the loop regions

263 structure upon RAG/HMGB1 binding and reveal structural differences, particularly near the heptamer,

264 knot region, and helical spine show distinct structural differences potentially important to signalin

265 onal structures has highlighted key tertiary structural differences, predominantly manifested in acti

266 isoforms vary in toxicity in accordance with structural differences, primarily in the number and patt

267 ed enzymes offer opportunities to reveal how structural differences produce different catalytic activ

268 egregated into parallel sub-bundles and show structural differences related to myelination.

269 rophic calcification processes could explain structural differences seen in GA skeletons and highligh

270 between multiple biogenic amines with remote structural differences six carbon atoms away from the bi

271 soil gammaproteobacteria suggest that these structural differences stem from evolutionary pressure t

272 Minor structural differences such as relative carbon-carbon do

273 atus PSII and spinach PSII, minor electronic structural differences that affect the manganese K-edge

274 t required for polymer export and has unique structural differences that allow the N-terminal deacety

275 of their CAPTR product ions, even for subtle structural differences that are not apparent from ion mo

276 s, but these dyes are not sensitive to local structural differences that distinguish amyloid strains.

277 gamma subunit working as a ratchet but with structural differences that make it a unique control mec

278 s (in the absence of concomitant gray matter structural differences) that predict processing speed.

279 Searching for structural differences, the crystal structure of Fe-SODA

280 pression levels, and (2) despite fundamental structural differences, the mechanisms mediating DNA acc

281 ckbone hydrogen bonds, they display distinct structural differences: the chains are kinked, enabling

282 id A structures and the contribution of each structural difference to the ability of lipid A to activ

283 ertheless, because plant cells exhibit major structural differences to animal cells, the question ari

284 laining kinesin processivity and for mapping structural differences to functional differences in dive

285 s of Bcr-Abl p210, which constitute the only structural differences to p190.

286 These structural differences, together with our molecular dyna

287 Moreover, no structural difference was detected between the phosphate

288 To investigate the functional impact of this structural difference, we compared the structure and fun

289 Baseline and longitudinal structural differences were compared using voxel-based m

290 Muscle structural differences were confirmed by histological an

291 Moreover, these structural differences were observed solely in the right

292 ere, we mainly investigated whether specific structural differences were present in MDD patients with

293 nservation of structure, combined with their structural differences when compared with mammalian suga

294 Plant sphingolipids exhibit structural differences when compared with their mammalia

295 ity properties in gastric fluid due to their structural differences which may explain their different

296 ular modeling and used for the evaluation of structural differences with a Bgl3 that is inhibited by

297 are not truly bulk-like, due to their subtle structural differences with the bulk.

298 cial enzyme in dTTP homeostasis and identify structural differences within the active site that could

299 These findings suggest that there are structural differences within the optic nerve complex be

300 t cognate conformations of receptors display structural differences within their binding site where b