ライフサイエンスコーパス: structural protein

1 cer-promoter interactions do not employ this structural protein.

2 ized by an interaction with a scaffolding or structural protein.

3 erves as anti-oxidative enzyme but also as a structural protein.

4 is, glycogen accumulation, and alteration of structural proteins.

5 ly composed of spidroins, a unique family of structural proteins.

6 rus containing the chikungunya virus (CHIKV) structural proteins.

7 viral DNA replication and synthesis of viral structural proteins.

8 is confirmed downregulation of metabolic and structural proteins.

9 tion (Hyp-Ara) found abundantly on cell wall structural proteins.

10 d in series through a network of elastic and structural proteins.

11 pressing premembrane and envelope Zika virus structural proteins.

12 t of five conserved genes that encode virion structural proteins.

13 rate, or the molecular interactions of viral structural proteins.

14 dramatic conformational changes within viral structural proteins.

15 saging the tc-VLPs on cells expressing CCHFV structural proteins.

16 neration genetically engineered self-healing structural proteins.

17 (VLVs) that contain VSV G but no other viral structural proteins.

18 transcription factors are regulated by these structural proteins.

19 alpains, and proteolytic breakdown of muscle structural proteins.

20 cleavable element between the capsid and PE2 structural proteins.

21 on and packaging of key viral regulators and structural proteins.

22 or family member proteins and Zika virus non-structural proteins.

23 ssembly by interacting with all of the other structural proteins.

24 Dengue non-structural protein 1 (NS1 DENV) is considered a biomarke

25 Non-structural protein 1 (NS1) facilitates flavivirus acquis

26 GNS1) and to favor specific detection of non-structural protein 1 (NS1) of dengue fever.

27 Bluetongue virus (BTV) non-structural protein 1 (NS1) regulates viral protein synth

28 ce (RNAi) suppressor activity of the IAV non-structural protein 1 (NS1), reported over a decade ago(2

29 ence mechanisms via the virulence factor non-structural protein 1 (NS1).

30 Influenza B virus encodes non-structural protein 1 (NS1B) that binds human ISG15 and p

31 se polyproteins at three sites releasing non-structural protein 1 (nsp1), nsp2, and nsp3.

32 atial relationships between nsP3 and the non-structural protein 1 (nsP1).

33 , a C terminally extended version of its non-structural protein 1, the expression of which enhances n

34 Non-structural protein 15 (Nsp15) has emerged as a promising

35 In SARS coronaviruses, the non-structural protein 16 (nsp16), in conjunction with nsp10

36 predominantly comprised of a BTV-encoded non-structural protein 2 (NS2).

37 identified a natural polymorphism in the non-structural protein 2 A (NS2A) that increase the virulenc

38 Non-structural protein 3 (nsp3) is the largest nsp in the co

39 The non-structural protein 3 (nsP3) plays essential roles during

40 ncodes the conserved macro domain within non-structural protein 3.

41 human STAT2 (hSTAT2) in complex with the non-structural protein 5 (NS5) of Zika virus (ZIKV) and deng

42 The non-structural protein 5A (NS5A) is a hepatitis C virus (HCV

43 HCV non-structural protein 5A (NS5A) is a multifunctional protei

44 Non-structural protein 5B (NS5B) is the RNA-dependent RNA po

45 ther heterogeneity in phosphorylation of key structural proteins alters tissue integrity and organ fu

46 ow collagen, the most abundant extracellular structural protein, alters its organization during fibro

47 restriction modification enzymes, and virion structural proteins, although the specific traits and se

48 orylation may partition F17's functions as a structural protein and mTOR regulator.

49 in the 0 and +1 frames to produce the viral structural proteins and a +1 overlapping open reading fr

50 s require dynamic interactions between viral structural proteins and a variety of cellular factors.

51 y viruses to balance levels of enzymatic and structural proteins and by eukaryotic cells to enable is

52 ds, which are assembled from seven different structural proteins and composed of several core protein

53 imary neuronal cells that concentrates viral structural proteins and is a major site of capsid envelo

54 s integrity by controlling the expression of structural proteins and protecting Sertoli cells from ea

55 diseases, and yet most of their genes encode structural proteins and proteins involved in their repli

56 he CD4 T cell epitopes are derived from HCMV structural proteins and provide a population protection

57 roduce diverse protein products that include structural proteins and regulatory factors(1,2).

58 viral late genes, which generates capsid and structural proteins and requires the coordination of six

59 By screening the three structural proteins and seven nonstructural proteins pre

60 oth of which require the concerted action of structural proteins and sortases for their polymerizatio

61 suggest a tight interdependency between Gag structural proteins and the protease during the developm

62 tails concerted interactions among the viral structural proteins and the RNA genome.

63 JE patients were mostly CD4(+) and targeted structural proteins and the secreted protein NS1.

64 The Gag protein is the main retroviral structural protein, and its expression alone is usually

65 rotein 2A (NS2A protein) recruits viral RNA, structural proteins, and protease to the site of virion

66 ha phosphorylation, the translation of viral structural proteins, and virus production.

67 rotein, intracellular/extracellular enzymes, structural proteins, anti-stress/anti-disease protein, e

68 N-Glycosylation of the major structural proteins (archaellins) is important for their

69 ontrast to primary DENV2 infection, in which structural proteins are a minor component of the respons

70 e.g., secretory tissues, tissues abundant in structural proteins) are also tissues in which gene expr

71 gene encoding filaggrin (FLG), an epidermal structural protein, are the strongest risk factor identi

72 d concentration of individual regulatory and structural proteins as filopodia elongate and subsequent

73 ur model therefore describes the dynamics of structural proteins as they localize and assemble at the

74 These viruses encode conserved replicase and structural proteins as well as more diverse accessory pr

75 on were identified in spike and nucleocapsid structural proteins as well as the 3' untranslated regio

76 ueprints for capsids with the same number of structural proteins, as well as for capsid architectures

77 hat contains more than 450 subunits of seven structural proteins assembling into a prolate head and a

78 ng the potential risk of ADE associated with structural protein-based ZIKV vaccines.

79 sis and limiting the production of the viral structural proteins but had little effect on viral repli

80 he viral genome and the genes encoding viral structural proteins, by binding to and oligomerizing on

81 Here, we reconstruct the core structural protein (CA) of an HML2 retrovirus, assemble

82 vage of viral C-prM-E polyprotein into three structural proteins (capsid, premembrane, and envelope),

83 ater resulting in reduced pH in proximity of structural proteins causing protein denaturation.

84 llular localization of caveolae and caveolar structural proteins CAV-1 and Cavin-1 and that these def

85 Anthocyanin biosynthesis structural proteins chalcone synthases and flavonone 3-h

86 s identified preservation of epitopes of the structural protein collagen I.

87 The MutaBind server maps mutations on a structural protein complex, calculates the associated ch

88 We found that caveolin-1, a structural protein component of caveolar membranes, is a

89 Until now, the identity of the main structural protein components of the basal layer was unk

90 iginal soft tissue structures and the native structural proteins comprising them can persist across g

91 To determine which structural proteins conferred host range specificity, ch

92 In the insect cuticle, structural proteins (CPs) and the polysaccharide chitin

93 The VP40 matrix protein is a key structural protein critical for Ebola virus budding.

94 Here, we evaluate two non-enzymatic structural protein crosslinking mechanisms, Fenton chemi

95 We examined the roles of two chromatin structural proteins, Ctcf (CCCTC-binding factor) and Hmg

96 rgeted proteomics to quantify amounts of the structural proteins CURVATURE THYLAKOID1 (CURT1), includ

97 nfection-related proteins, including several structural proteins derived from the liver extracellular

98 Our findings indicate that structural proteins destined for the ciliary axoneme are

99 us-like particles (VLPs), comprised of viral structural proteins devoid of genetic material, are tuna

100 into the individual functions of a viral non-structural protein during infection with a medically imp

101 the relative expression of structural to non-structural proteins during different phases of the viral

102 DMD patients lack the expression of the structural protein dystrophin caused by mutations within

103 y (DMD) is caused by absence of the integral structural protein, dystrophin, which renders muscle fib

104 Finally, we discovered that ZIKV structural proteins (E, prM, and C) are major targets of

105 that FLIm parameters linked to the amount of structural proteins (e.g. collagen, elastin) and lipids

106 IgG avidity, and IgG response to the 3 viral structural proteins (E1, E2, and C), reflected by immuno

107 a putative fusion peptide (FP) in the major structural protein E2 of classical swine fever virus (CS

108 Structural protein-encoding genes constitute a large fra

109 2), and a fragment of the type III secretion structural protein EscC (pVAX-56.2), was able to induce

110 knockdown of RPLP1/2 reduced levels of DENV structural proteins expressed from an exogenous transgen

111 loss and reduced lipid synthesis enzyme and structural protein expression up to 96 hours postburn.

112 owever, TMPRSS2 overexpression decreased MHV structural protein expression, release of infectious par

113 ucleotide-dependent processes, expression of structural proteins, fatty acid and lipid metabolism in

114 y coordinated molecular system involving the structural protein filaggrin (FLG).

115 ings underscore the importance of retroviral structural proteins for integration site selection and t

116 Shank3 is a structural protein found predominantly at the postsynapt

117 Collagens are an important family of structural proteins found in the extracellular matrix wi

118 t cell culture-derived HCV (HCVcc) harboring structural proteins from a diverse array of HCV genotype

119 The finding suggests that recombinant structural proteins from heterologous expression have po

120 Structural proteins from naturally occurring materials a

121 In this work, we assessed the four structural proteins from SARS-CoV-2 for their ability to

122 proteins are translated from genomic RNA and structural proteins from subgenomic RNA.

123 amma-Catenin (Plakoglobin), a well-described structural protein functioning at the adherens junctions

124 The prototype foamy virus (PFV) structural protein GAG associates with chromosomes via a

125 The retroviral structural protein Gag binds to the inner leaflet of the

126 otably, our previous study showed that HIV-1 structural protein Gag colocalizes with a group of uropo

127 PM association of the main structural protein Gag depends on its myristoylated MA d

128 interaction of the viral RNA genome with the structural protein Gag facilitates virion assembly and p

129 The retroviral structural protein Gag has three major domains.

130 to virions, and RNA interacts with the viral structural protein Gag in the cytoplasm.

131 However, the structural protein Gag is the only component required fo

132 The structural protein Gag is the only viral component requi

133 In polarized T cells, HIV-1 structural protein Gag localizes to the plasma membrane

134 We previously showed that the HIV-1 structural protein Gag localizes to the uropod, a rear-e

135 Binding of the retroviral structural protein Gag to the cellular plasma membrane i

136 The correct ratio of the HIV-1 structural protein Gag to the envelope protein (Env) is

137 comitant with recruitment of the major HIV-1 structural protein Gag to the site of cell-cell contact.

138 The structural protein Gag, found in all retroviruses, is a

139 embly, determined by the localization of the structural protein Gag, vary in a cell-type-dependent ma

140 ing, initiated by oligomerization of the HIV structural protein Gag.

141 first spacer peptide (SP1) of the precursor structural protein, Gag.

142 cently, frameshift mutations in the caveolar structural protein gene Caveolin-1 (CAV-1) were identifi

143 F) density, sweat gland innervation index of structural protein gene product 9.5 (SGII[PGP9.5]) and p

144 Even deletions of one of the known structural protein genes that is present in all known fu

145 d transcription-associated genes and several structural protein genes.

146 , at 24 h postsurgery the mRNA expression of structural proteins (GFAP and AQP4) was compromised.

147 The Golgi structural protein GM130 is responsible for connecting d

148 s in the antibody responses to specific PEDV structural proteins have important implications in the d

149 Many globular and structural proteins have repetitions in their sequences

150 ts yielded 37 peptides from housekeeping and structural proteins (i.e., GroEL, EF-TU, rpL7/L2 and the

151 nant polypeptides derived from the four PEDV structural proteins, i.e., spike (S), nucleocapsid (N),

152 e six RNA segments encoding the prototypical structural proteins identified in other quaranjaviruses,

153 nse supports a central role for this nuclear structural protein in cellular homeostasis.

154 Here, we show that actin, the most abundant structural protein in eukaryotes, binds the LL-37 host d

155 P. destructans, and that collagen, the major structural protein in mammals, is actively degraded by t

156 f many proteins, including collagen, the key structural protein in mammals.

157 Protein zero (P0) is the major structural protein in peripheral myelin, and mutations i

158 P30 plays an integral role as a cross-linked structural protein in the formation of lightweight rigid

159 ased tension biosensor for nesprin-2G, a key structural protein in the LINC complex, which physically

160 the ribosome and drives translation of viral structural proteins in a factor-independent manner.

161 Keratin is one of the most important structural proteins in nature to be used as biomaterial

162 nome-length chimeric HCV RNAs encoding GBV-B structural proteins in place of equivalent HCV sequences

163 e arrangement of collagen, elastin and other structural proteins in space and time embodies our tissu

164 amin B1 (LMNB1) constitutes one of the major structural proteins in the lamina mesh.

165 The progressive breakdown of structural proteins, in particular, medial elastin, is r

166 t intrinsic defects in the expression of key structural proteins including cytokeratin-10 and loricri

167 adenovirus vector expressing hepacivirus non-structural proteins induces effective immunity in majori

168 N-RESEMBLING CHLOROPLAST PROTEIN, a proposed structural protein influential in starch granule initiat

169 tion that binds to the ACTN2 gene, a crucial structural protein inside the cardiac sarcolemma (Hi-C i

170 How HSV-1 structural proteins interact with ESCRT components and w

171 omains of gE/gI promote the sorting of viral structural proteins into proximal axons to begin axonal

172 e SDVs and regulating the insertion of other structural proteins into the SDV.

173 er, the results suggest that Sfp1 is a major structural protein involved in footprint cohesion and po

174 ading frames in common that appear to encode structural proteins involved in interaction with the hos

175 For retroviruses, the Gag structural protein is the primary driver of virus partic

176 does not suppress the expression of HIV non-structural proteins, it has been proposed that a constit

177 including receptors, transcription factors, structural proteins, kinases, and metabolic enzymes.

178 Within this context, unique structural proteins known as reflectins have recently at

179 We describe the quantitative distribution of structural proteins, known and previously undescribed pr

180 The human papillomavirus (HPV) major structural protein L1 composes capsomers that are linked

181 uric syndromes resulting from defects in GBM structural proteins (laminin beta2 or collagen alpha3 IV

182 changes are highly diverse, with examples in structural protein levels, the DNA repair machinery, and

183 pping, we found that polymorphisms in JHM.WU structural protein M and nonstructural replicase protein

184 ral entry but rather on a combination of the structural protein M and nonstructural replicase-associa

185 We hypothesized that HIV structural proteins may contribute to lymphomagenesis di

186 Together, these findings reveal that nuclear structural proteins may exert bimodal transcriptional ef

187 s then assessed by 2 predictive scores and a structural protein modelling.

188 oV-2 directed T-cell immunotherapy targeting structural proteins, most importantly membrane protein,

189 found that two fragments of the myofibrillar structural protein myomesin-3 (MYOM3) are abnormally pre

190 nct myocardial subpopulations expressing the structural proteins myosin heavy chain alpha and myosin

191 he threshold for loss of solubility, and the structural proteins, myosin and actin, lost their native

192 potent newly identified inhibitors were KSHV structural proteins, namely ORF22 (glycoprotein H), ORF2

193 We present immunohistochemical data of structural proteins (NF200, Ankyrin G, and Myelin) and i

194 genase function in plants, expression of the structural proteins NifD and NifK will be an absolute re

195 The viral non-structural protein NS1, rather than a viral surface prot

196 The DENV non-structural protein NS4B and subgenomic flavivirus RNA in

197 that TRIM14 interacted with HCV encoded non-structural protein NS5A and could strongly induce its de

198 en its antibody response in three common non-structural protein (NSP) ELISAs and its age.

199 i-subunit RNA-synthesis complex of viral non-structural proteins (nsp) responsible for the replicatio

200 ow that binding of the rotavirus-encoded non-structural protein NSP2 to viral ssRNAs results in the r

201 y, for the first time, suggests that the non-structural protein NSs of CCHFV, a member of the genus N

202 SFSTV non-structural protein (NSs) has been shown to block type I

203 nce depends on the interferon antagonist non-structural protein (NSs), which remains poorly character

204 53BP1 interacts with the structural protein NuMA, which controls 53BP1 diffusion.

205 the cleavage of type II collagen, the major structural protein of articular cartilage.

206 Mutations in collagen II, a main structural protein of cartilage, are associated with var

207 Caveolin-3 is the major structural protein of caveolae in muscle.

208 colocalized with caveolin-1 (Cav-1), the key structural protein of caveolae.

209 y interacts with caveolin-1 (Cav-1), the key structural protein of caveolae.

210 e alpha3 chain of laminin 332 (LAMalpha3), a structural protein of epidermal/epithelial basement memb

211 ession is inhibited by apolipoprotein B, the structural protein of low-density lipoprotein, which bin

212 The major structural protein of MLV particles, Gag, frequently co-

213 ratory show that the ExsY protein is a major structural protein of the exosporium basal layer of B. c

214 h PMA, and upon viral budding, ASP becomes a structural protein of the HIV-1 envelope.

215 Elastin is an essential structural protein of the lungs.

216 Circoviral capsid protein is the only structural protein of the virion that plays an essential

217 Caveolins (CAVs) are structural proteins of caveolae that function as signali

218 ther, we demonstrate for the first time that structural proteins of KSHV can counteract p53-induced a

219 Virions composed of the structural proteins of one flavivirus and the genomic RN

220 subgenomic RNA could readily be packaged by structural proteins of the DENV2 strain 16681, productio

221 lex pathways that often converge on the main structural proteins of the nucleus, the lamins.

222 We produced recombinant WNV with the structural proteins of the NY99 or Eg101 strain (NY-WT o

223 esence of MoRF regions in structural and non-structural proteins of Zika virus using an aforementione

224 ed by a layer of phospholipids and the small structural protein oleosin.

225 lassify phage ORFs into ten major classes of structural proteins or into an "other" category.

226 mbers of the order Nidovirales express their structural protein ORFs from a nested set of 3' subgenom

227 reassemble the key proteolytic product, the structural protein p24 (CA), into a distinct, mature hex

228 lls (hASCs) by knocking down 2 primary cilia structural proteins, polycystin-1 and intraflagellar pro

229 Here, we show that if a given structural protein positively regulates its own gene exp

230 ne of the 'hit' peptoids bound to plectin, a structural protein, predominantly expressed intracellula

231 VP24 protein, a structural protein present in all family members, blocks

232 (viral RNA, certain replicases, and certain structural proteins) present in/on the intercellular nan

233 Our designed sequences are based on a structural protein produced in squid suction cups that h

234 n natural systems, directed self-assembly of structural proteins produces complex, hierarchical mater

235 Structural protein:protein interaction studies reveal th

236 as the site for coat assembly; and SpoIVA, a structural protein recruited by SpoVM that uses ATP hydr

237 indings reveal distinct roles for Zap70 as a structural protein regulating integrin-mediated control

238 sign and structure-property relationships of structural proteins remains unclear.

239 ng the two viral polypeptides to release non-structural proteins required for viral replication.

240 Junctophilin-2 (JP2) is a structural protein responsible for jSR/T-tubule docking.

241 es called ribbons, composed primarily of the structural protein Ribeye.

242 l analysis also revealed the presence of HCV structural proteins, RNA, and apolipoproteins in the Gol

243 2p/Snf2p, interacts with the heterochromatin structural protein Sir3p.

244 ne from both nonstructural protein (nsP) and structural protein (sP) open reading frames (ORFs).

245 The detection of antibodies against the structural proteins (SP) of the capsid can be used to mo

246 he detection of antibodies (Ab) against FMDV structural proteins (SP) using virus neutralization test

247 esidues absent from previous biochemical and structural protein studies.

248 in AD is caused by phosphorylation of Golgi structural proteins, such as GRASP65, which is induced b

249 ence for adaptive evolution, particularly of structural proteins, suggesting that most viral lineages

250 mutations did not affect RNA replication or structural protein synthesis but had deleterious effects

251 onal protein modifications, and their target structural protein TCHH are all involved in hair shaft f

252 he maturation stage, and thus knowledge of a structural protein template that could guide enamel mine

253 kerin modules to repeated cohesin modules of structural proteins termed scaffoldins.

254 replication capacity driven by Gag, a major structural protein that is a significant determinant of

255 s appears to be the first example of a viral structural protein that is also involved in the transcri

256 The VP40 matrix protein is a key viral structural protein that is critical for virion egress.

257 These data show that ATF5 is an essential structural protein that is required for the interaction

258 encode the nucleocapsid (N) protein, a major structural protein that plays multiple roles in the viru

259 ciated vertical filaments, are the essential structural proteins that anchor and organize both types

260 Collagens are large structural proteins that are prevalent in mammalian conn

261 Cytoskeletons are cell structural proteins that closely relate to migration, an

262 Structural proteins that connect the cell to its niche,

263 PH1 functions as a hub linking key motor and structural proteins that contain intrinsically disordere

264 D88-dependent abnormalities in expression of structural proteins that contribute to skin barrier func

265 ammals, prohibitins (PHBs) are considered as structural proteins that form a scaffold-like structure

266 Neurofilaments (Nf) are major structural proteins that occur exclusively in neurons.

267 llular matrix (ECM) is a complex assembly of structural proteins that provides physical support and b

268 factors regulate the expression of the lens structural proteins, the crystallins.

269 , solute transport, signal transduction, and structural proteins, the hypothesis naturally arises tha

270 ClO2 inactivates MS2 by degrading its structural proteins, thereby disrupting the ability of M

271 e oxidizing capsular protein thiols and as a structural protein, tightly controlled expression of fun

272 ed to truncating mutations in the sarcomeric structural protein titin (TTNtv).

273 ere, we present templated crystallization of structural proteins to nanofabricate hierarchically stru

274 s viral RNA, certain replicases, and certain structural proteins to neighboring cells.

275 is accuracy, we uncover interactions between structural proteins, transcription factors, epigenetic m

276 differentiated neurons by facilitating viral structural protein translation.IMPORTANCE Mosquito-borne

277 Proteomics identified structural protein vimentin as an additional VEGF-HO-1 t

278 capsid assembly, namely, trafficking of the structural proteins (VP) to the nuclear site of assembly

279 The thirteen-residue peptide binds to major structural protein VP1 with single-digit nanomolar affin

280 MEV nonstructural proteins (NS1 and NS2) and structural proteins (VP1 and VP2), we demonstrated that

281 proteins (NS1, 11-kDa, and 7.5-kDa) and two structural proteins (VP1 and VP2).

282 During infection, B19V expresses two structural proteins, VP1 and VP2, and three nonstructura

283 derived from the BK polyomavirus (BKV) minor structural proteins VP2/3 that is a potent inhibitor of

284 onstructural proteins (NSPs) 2, 5, and 6 and structural proteins (VPs) 1, 2, 3, and 6.

285 involving nonstructural proteins (NSPs) and structural proteins (VPs).

286 However, the translation of structural proteins was impaired, phosphorylation of the

287 virions with DENV2 strain New Guinea C (NGC) structural proteins was not possible, despite the very h

288 tability and steady-state levels of two T4SS structural proteins were affected by a homolog of tail-s

289 lycolytic process and decrease in myocardial structural proteins were differentially expressed compar

290 The genes coding for structural proteins were more permissive to mutations.

291 ) currents as well as decrease in myocardial structural proteins were observed in LV.

292 mained unaffected, whereas the levels of PSI structural proteins were severely diminished, indicating

293 The Gag structural proteins were the most abundant viral protein

294 fic deletion of CTCF (a ubiquitous chromatin structural protein) were generated to explore the role o

295 l to study the molecular neighborhood of any structural protein whose interactions change either duri

296 Collagen is a structural protein whose internal cross-linking critical

297 d blood - with a focus on a few key abundant structural proteins whose expression dynamics have been

298 -dependent RNA-polymerase, glycoprotein, non-structural protein with a Zinc-Finger domain and a nucle

299 ced viral assembly and induced clustering of structural proteins with non-structural HCV proteins, in

300 nd that deviations in the composition of key structural proteins within MRL/MpJ vs C57Bl/6 tendons oc